CN111588810A - Traditional Chinese medicine composition for treating calculus - Google Patents

Traditional Chinese medicine composition for treating calculus Download PDF

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Publication number
CN111588810A
CN111588810A CN202010593432.3A CN202010593432A CN111588810A CN 111588810 A CN111588810 A CN 111588810A CN 202010593432 A CN202010593432 A CN 202010593432A CN 111588810 A CN111588810 A CN 111588810A
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traditional chinese
chinese medicine
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medicine composition
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仲崇允
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/24Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/59Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/69Polygalaceae (Milkwort family)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/04Drugs for disorders of the urinary system for urolithiasis

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Abstract

The invention discloses a traditional Chinese medicine composition for treating calculi, which is prepared from the following raw material medicines in parts by weight: frangipani, Japanese polygala, abelmoschus manihot, longtube ground ivy herb, Japanese climbing fern herb, phyllanthus urinaria, creeping dichondra, achyranthes aspera, field euphorbia stem, common nepenthes, sunflower, Sichuan valley root and felwort. According to the traditional Chinese medicine composition for treating the calculus, through mutual matching and coordination of the raw materials, the traditional Chinese medicine composition has the effects of clearing heat and removing toxicity; promoting urination and treating stranguria; promoting blood circulation and removing blood stasis; has the efficacy of detumescence and the like, and has good curative effect on the calculus.

Description

Traditional Chinese medicine composition for treating calculus
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating calculus.
Background
Calculus is a solid mass formed in the lumen of a catheter or in the lumen of a luminal organ (e.g., kidney, ureter, gall bladder, etc.) in the body. It is mainly found in gallbladder, bladder and renal pelvis, and also in pancreatic duct, salivary duct, etc. Calculus is composed of inorganic salts or organic substances. The stone generally has a core consisting of exfoliated epithelial cells, bacterial mass, parasite eggs or bodies, fecal mass or foreign matter, and inorganic salts or organic matter deposited layer by layer on the core. Calculus can cause obstruction of the lumen, affecting the drainage of fluid from the affected organs, causing pain, bleeding or secondary infection. At present, no specific medicine for treating calculus exists.
Disclosure of Invention
The invention aims to improve the defects of the prior art and provide the traditional Chinese medicine composition for treating the calculus, which can effectively improve or even eliminate the clinical symptoms of patients and has the characteristics of obvious treatment effect, short treatment period, no toxic or side effect and the like.
Urinary calculus belongs to the categories of 'urolithiasis' and 'sand stranguria' in the 'stranguria syndrome' of traditional Chinese medicine. The Donghan Zhang machine is specifically described in the Jingui diabetes stranguria-treating syndrome-collateral-flow treatment of diabetes, which is characterized by: stranguria is caused by the urinary bladder being in the form of a millet, wiry and urgent lower abdomen, which leads to pain in the umbilicus. "in turn indicates: when heat is in the lower energizer, it can cause hematuria and stranguria. The accurate description in Tang Dynasty Sun Simiao (Beiji Qianjin essentials prescription) is also included: shilin is a disease with pain in the stem and retention of urine. "Song Dynasty" Danxi Xin Fa "said: "all stranguria caused by kidney deficiency and bladder heat generation, water and fire were not mixed, bladder was urgent, and there was no desire to go out and stop dripping of the chylous sandstone … … when urination was too hard, even choking between them . "all stranguria should be characterized by frequent and urgent urination, dribbling pain, spasm of lower abdomen, and pain in the umbilical abdomen. Urinary calculus with the symptom of stranguria and discharge of sand and stone can be diagnosed as stranguria; if the patient suffers from burning pain due to red heat or accompanied by heat, the patient should be diagnosed with heat stranguria; stranguria with bloody urine can be diagnosed when it is painful. For calculus, heat-clearing and toxicity-removing; promoting urination and treating stranguria; promoting blood circulation, removing blood stasis and relieving swelling, thereby achieving the purpose of thorough cure.
Based on the theory, the invention provides a traditional Chinese medicine for treating calculus, which is prepared from the following raw material medicines in parts by weight: 5-10 parts of frangipani; 7-15 parts of polygala japonica; 9-18 parts of abelmoschus manihot seeds; 15-30 parts of longtube ground ivy herb, climbing fern herb, phyllanthus urinaria, creeping dichondra, achyranthes aspera, field euphorbia stem, pitcher plant, sunflower and Sichuan valley root; 30-60 parts of Chinese alpine rush
In a preferred embodiment, the traditional Chinese medicine composition for treating calculus comprises the following raw material medicines in parts by weight: 10 parts of frangipani; 15 parts of Japanese polygala; 18 parts of abelmoschus manihot seeds; 30 parts by weight of longtube ground ivy herb, climbing fern herb, phyllanthus urinaria, creeping dichondra, achyranthes aspera, field euphorbia stem, pitcher plant, sunflower and Sichuan valley root; orthosiphon aristatus (Bull.) Radde 60 weight parts
Wherein, the Chinese alpine rush: sweet in taste; diluting; slightly bitter; is cool in nature. Clearing heat and promoting diuresis; treating stranguria and removing urinary calculus. Can be used for treating urinary calculus; gallstones, and the like.
Common nepenthes: sweet in taste; diluting; and (6) cooling. Entering the lung; a bladder; the stomach meridian. Moistening lung to arrest cough; clearing heat, promoting diuresis and removing calculus; detoxify and detumescence. Can be used for treating lithangiuria.
And (3) carrying out scutellariae pterocarpus: astringent and cool. Diminish inflammation, induce diuresis, clear heat and expel stones. It can be used for treating urinary tract infection, lithangiuria, cystitis, etc.
Herba Glechomae: pungent, slightly bitter and slightly cold in flavor. It enters liver, kidney and bladder meridians. Induce diuresis to treat stranguria, clear away heat and toxic material, dissipate blood stasis and relieve swelling. It can be used for treating heat stranguria and urolithic stranguria. Can make urine become acidic, and dissolve calculus under alkaline condition.
Herba talinae: pungent and mild in flavor. Clear heat and promote diuresis, remove toxicity and relieve swelling. Can be used for treating urinary system infection and urinary calculus.
Abelmoschus manihot seed: sweet and cold in nature. Clear heat and remove toxicity, moisten dryness and smooth intestines. Can be used for treating dysuria, edema, lithangiuria, etc.
Phyllanthus urinaria L: slightly bitter, sweet and cool. Clear heat and induce diuresis, improve eyesight and remove food retention. Can be used for treating nephritis, edema, urinary system infection, calculus, etc.
B, Baijie vine: is bitter in taste; is cold. Entering the lung; the large intestine; the liver meridian. Clearing away heat and toxic materials; dispelling pathogenic wind and relieving pain; induce diuresis to treat stranguria. Can be used for treating urinary tract infection and lithangiuria.
Achyranthes aspera: slightly bitter and cool. Clear heat, remove toxicity, induce diuresis. Can be used for treating urinary calculus, nephritis, edema, etc.
Egg flower: sweet in taste; slightly bitter; is cool in nature. Entering the lung; the large intestine channel. Clearing away heat; removing dampness; relieving summer-heat. Can be used for treating lithangiuria, etc
Japanese milkwort herb: slightly pungent and warm. Promoting blood circulation, removing blood stasis, eliminating phlegm, relieving cough, removing toxic substance, and relieving pain. Can be used for treating urinary calculus.
Herba talinae: pungent and mild in flavor. Clear heat and promote diuresis, remove toxicity and relieve swelling. Can be used for treating hepatitis, cholecystitis, dysentery, nephritis, edema, urinary system infection, urinary calculus, tonsillitis, and traumatic injury.
Sunflower: bland in flavor and mild in taste. Clear heat and induce diuresis, relieve cough and relieve asthma. Can be used for treating difficult and painful urination, lithangiuria, etc.
Sichuan valley root: sweet, bland and slightly cold in flavor. Clear heat, remove dampness by diuresis, kill parasites. Can be used for treating urinary tract infection and lithangiuria.
The invention is prepared from Chinese traditional herbal medicines, and the traditional Chinese medicine for effectively treating calculi is formed by orderly matching certain natural extracts with definite components and clear effects according to a plurality of principles of traditional Chinese medicine treatment based on syndrome differentiation and modern medicine.
The invention can run through the whole process of calculus treatment, treats both principal and secondary aspects of diseases, is not easy to relapse, is safe and reliable, has no obvious toxic and side effects, is convenient for patients to insist on taking for a long time, has no adverse reaction for the patients after taking the medicine for years, and tracks the blood examination to be normal.
The traditional Chinese medicine composition has the advantages of easily available raw materials, simple process, low cost and high efficiency, and is beneficial to pharmaceutical enterprises for medicine production and quality control; the product has low price and is easy to be accepted by patients.
The traditional Chinese medicine composition has a remarkable effect of treating the calculus, and clinical experiment results show that the formula is used for treating the calculus, one dose of the traditional Chinese medicine composition is taken every day, 100 ml of water is decocted, the traditional Chinese medicine composition is divided into two parts, one part is taken in the morning and the evening, one month is taken as a treatment course, the traditional Chinese medicine composition takes effect in one treatment course generally, and the calculus is basically cured in two to four treatment courses. The cure rate is 92 percent, and the total effective rate is 100 percent.
The invention also provides an oral preparation prepared from the traditional Chinese medicine composition for treating calculi, which comprises oral liquid, tablets, capsules, pills and the like, wherein the preferable dosage forms are tablets and capsules, and one dose is taken every day in the morning and at night.
The traditional Chinese medicine composition can be prepared into various dosage forms. For example, the decocted liquid medicine is sterilized and disinfected and then packaged to prepare oral liquid; or concentrating the decoction, oven drying, adding pharmaceutically acceptable adjuvants, and making into tablet, capsule, pill, etc.
The medically acceptable auxiliary materials comprise starch, dextrin, sodium carboxymethylcellulose, polyethylene glycol, calcium hydrophosphate, sodium alginate, potassium sorbate and the like.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the present invention in any way, and it will be apparent to those skilled in the art that the above description of the present invention can be applied to various modifications, equivalent variations or modifications without departing from the spirit and scope of the present invention.

Claims (4)

1. The traditional Chinese medicine for treating calculi is characterized by comprising the following raw material medicines in parts by weight: 5-10 parts of frangipani; 7-15 parts of polygala japonica; 9-18 parts of abelmoschus manihot seeds; 15-30 parts of longtube ground ivy herb, climbing fern herb, phyllanthus urinaria, creeping dichondra, achyranthes aspera, field euphorbia stem, pitcher plant, sunflower and Sichuan valley root; 30-60 parts of Chinese alpine rush.
2. The traditional Chinese medicine for treating calculi as claimed in claim 1, which is characterized by comprising the following raw material medicines in parts by weight: 10 parts of frangipani; 15 parts of Japanese polygala; 18 parts of abelmoschus manihot seeds; 30 parts by weight of longtube ground ivy herb, climbing fern herb, phyllanthus urinaria, creeping dichondra, achyranthes aspera, field euphorbia stem, pitcher plant, sunflower and Sichuan valley root; 60 parts of Chinese alpine rush.
3. An oral preparation for treating calculi, which is characterized by being prepared from the traditional Chinese medicine composition of any one of claims 1 or 2.
4. The oral preparation for treating calculi according to claim 3, which is characterized by comprising oral liquid, tablets, capsules and pills, preferably oral liquid and tablets.
CN202010593432.3A 2020-06-27 2020-06-27 Traditional Chinese medicine composition for treating calculus Pending CN111588810A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104056091A (en) * 2014-06-18 2014-09-24 合肥瑾翔医药科技有限公司 Traditional Chinese medicine decoction for treating pharyngolaryngitis
CN105079333A (en) * 2014-05-14 2015-11-25 黄思齐 Medicine for treating urinary calculi
CN105535914A (en) * 2016-01-30 2016-05-04 王廷波 Traditional Chinese medicine composition for treating cholecystitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105079333A (en) * 2014-05-14 2015-11-25 黄思齐 Medicine for treating urinary calculi
CN104056091A (en) * 2014-06-18 2014-09-24 合肥瑾翔医药科技有限公司 Traditional Chinese medicine decoction for treating pharyngolaryngitis
CN105535914A (en) * 2016-01-30 2016-05-04 王廷波 Traditional Chinese medicine composition for treating cholecystitis

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