CN111588808A - Traditional Chinese medicine skin disinfectant fluid and preparation method thereof - Google Patents

Traditional Chinese medicine skin disinfectant fluid and preparation method thereof Download PDF

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Publication number
CN111588808A
CN111588808A CN202010246751.7A CN202010246751A CN111588808A CN 111588808 A CN111588808 A CN 111588808A CN 202010246751 A CN202010246751 A CN 202010246751A CN 111588808 A CN111588808 A CN 111588808A
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parts
chinese medicine
traditional chinese
skin
glycerol
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马润林
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Jiangsu Qianbao Biotechnology Co ltd
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Jiangsu Qianbao Biotechnology Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
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    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/534—Mentha (mint)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/898—Orchidaceae (Orchid family)
    • A61K36/8984—Dendrobium
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    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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Abstract

The invention discloses a traditional Chinese medicine skin disinfectant fluid and a preparation method thereof, the disinfectant fluid consists of traditional Chinese medicine extracting solution, chlorhexidine acetate, PEG400, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan, glycerol, povidone iodine, lecithin powder, a water-soluble coupling agent, a skin care agent and plasma water, and the components in parts by weight are as follows: 20-35 parts of traditional Chinese medicine extracting solution; 3-7 parts of chlorhexidine acetate; 5-10 parts of PEG 400; 2-5 parts of sodium dodecyl sulfate; 3-7 parts of polyhexamethylene guanidine hydrochloride; 1-4 parts of chitosan; 6-12 parts of glycerol; 8-15 parts of glycerol; 5-10 parts of povidone iodine; 3-7 parts of lecithin powder. The traditional Chinese medicine extract is used as a raw material, has the advantages of obvious effect, low cost, detumescence, acesodyne, obvious sterilization and bacteriostasis effects, can be quickly absorbed by skin, does not generate strong stimulation to the skin, does not cause damage to subcutaneous tissues, and simultaneously has the functions of moistening the skin, improving the recovery rate of the skin and preventing various skin diseases.

Description

Traditional Chinese medicine skin disinfectant fluid and preparation method thereof
Technical Field
The invention relates to the technical field of disinfectant fluid, in particular to traditional Chinese medicine skin disinfectant fluid and a preparation method thereof.
Background
Skin refers to the tissue of the body surface outside the muscle, which is the largest organ of the human body and mainly plays the roles of protecting the body, perspiring, sensing cold and heat and pressure, the skin covers the whole body, various tissues and organs in the body are prevented from being invaded by physical, mechanical, chemical and pathogenic microorganisms, the skin of people and higher animals consists of three layers of epidermis, dermis and subcutaneous tissue, and disinfectant water is needed when the skin is disinfected, but the existing disinfectant water is not ideal in bacteriostatic effect, and simultaneously, the skin is easy to be irritated to cause skin allergy.
Disclosure of Invention
The invention aims to provide traditional Chinese medicine skin disinfectant fluid and a preparation method thereof, and aims to solve the problems in the background art.
In order to achieve the purpose, the invention provides the following technical scheme: a traditional Chinese medicine skin disinfectant fluid is composed of traditional Chinese medicine extracting solution, chlorhexidine acetate, PEG400, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan, glycerol, povidone iodine, lecithin powder, a water-soluble coupling agent, a skin care agent and plasma water, and comprises the following components in parts by weight: 20-35 parts of traditional Chinese medicine extracting solution; 3-7 parts of chlorhexidine acetate; 5-10 parts of PEG 400; 2-5 parts of sodium dodecyl sulfate; 3-7 parts of polyhexamethylene guanidine hydrochloride; 1-4 parts of chitosan; 6-12 parts of glycerol; 8-15 parts of glycerol; 5-10 parts of povidone iodine; 3-7 parts of lecithin powder; 10-15 parts of a water-soluble coupling agent; 4-10 parts of a skin care agent; 100 portions and 150 portions of plasma water.
Preferably, the traditional Chinese medicine extracting solution is obtained by steaming and filtering raw materials, and the raw materials consist of honeysuckle, mint, angelica dahurica, selfheal, houttuynia cordata, asarum, isatis root, gastrodia elata, dendrobium, garden balsam stem, patchouli and macrocyclic triterpenoid saponin, and the traditional Chinese medicine extracting solution comprises the following components in parts by weight: 10-15 parts of honeysuckle; 8-15 parts of mint; 3-7 parts of radix angelicae; 6-12 parts of selfheal; 2-5 parts of houttuynia cordata; 1-4 parts of asarum; 15-22 parts of isatis root; 2-6 parts of gastrodia elata; 4-10 parts of dendrobium; 3-7 parts of garden balsam stem; 2-5 parts of cablin potchouli herb; 8-15 parts of macrocyclic triterpenoid saponin.
Preferably, the water-soluble coupling agent consists of carbomer, ethylene diamine tetraacetic acid, organic acid, mica powder, hydroxyethyl cellulose, calcium triethyl diamine tetraacetate, nonylphenol polyoxyethylene ether, histidine, lactic acid, glycerol and distilled water, and the water-soluble coupling agent comprises the following components in parts by weight: 8-15 parts of carbomer; 3-7 parts of ethylene diamine tetraacetic acid; 1-3 parts of organic acid; 2-5 parts of mica powder; 3-9 parts of hydroxyethyl cellulose; 4-6 parts of triethyl diamine tetraacetate calcium; 4-10 parts of nonylphenol polyoxyethylene ether; 5-8 parts of histidine; 3-8 parts of lactic acid; 15-25 parts of glycerol; 40-55 parts of distilled water.
Preferably, the skin care agent consists of glycerin, saponin essence, a coupling agent, liquid paraffin, essence, collagen, hydroxyethyl cellulose, dibutyl phthalate and deionized water, and comprises the following components in parts by weight: 6-10 parts of glycerol; 30-50 parts of saponin essence; 13-20 parts of a coupling agent; 2-6 parts of liquid paraffin; 3-7 parts of essence; 2-8 parts of collagen; 3-9 parts of hydroxyethyl cellulose; 3-10 parts of dibutyl phthalate; 40-80 parts of deionized water.
A preparation method of traditional Chinese medicine skin disinfectant fluid comprises the following steps:
A. ball milling: respectively putting chlorhexidine acetate, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan and lecithin powder into a ball mill for ball milling treatment, wherein the ball milling particle size is 80-150 meshes;
B. soaking: putting chlorhexidine acetate, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan and lecithin powder in a box body in parts by weight, then adding traditional Chinese medicine extracting solution, PEG400, glycerol, povidone iodine, a water-soluble coupling agent, a skin care agent and plasma water in parts by weight, and soaking for 25-40 d;
C. and (3) precipitation: pouring the soaked mixed solution into a precipitation box, and precipitating for 20-30 h;
D. taking clear liquid: pouring the suspension into a filling machine from the filter screen;
E. filling: filling the clear liquid in the filling machine into a bottle;
F. and packaging and warehousing after the inspection is qualified.
Preferably, the box body in the step B is matched with a heating device, the heating device is an infrared heater, a graphite furnace or an electron beam heater, the heating temperature is 30-50 ℃, and meanwhile, the stirring is carried out once every 20-30h in the step B, and the stirring time is 8-15 min.
Compared with the prior art, the invention has the following beneficial effects:
the traditional Chinese medicine extract is used as a raw material, has the advantages of obvious effect, low cost, detumescence, acesodyne, obvious sterilization and bacteriostasis effects, can be quickly absorbed by skin, does not generate strong stimulation to the skin, does not cause damage to subcutaneous tissues, and simultaneously has the functions of moistening the skin, improving the recovery rate of the skin and preventing various skin diseases.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The first embodiment is as follows:
a traditional Chinese medicine skin disinfectant fluid is composed of traditional Chinese medicine extracting solution, chlorhexidine acetate, PEG400, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan, glycerol, povidone iodine, lecithin powder, a water-soluble coupling agent, a skin care agent and plasma water, and comprises the following components in parts by weight: 20 parts of traditional Chinese medicine extracting solution; 3 parts of chlorhexidine acetate; PEG4005 parts; 2 parts of sodium dodecyl sulfate; 3 parts of polyhexamethylene guanidine hydrochloride; 1 part of chitosan; 6 parts of glycerol; 8 parts of glycerol; 5 parts of povidone iodine; 3 parts of lecithin powder; 10 parts of a water-soluble coupling agent; 4 parts of a skin care agent; 100 parts of plasma water.
The traditional Chinese medicine extract is used as a raw material, has the advantages of obvious effect, low cost, obvious effects of detumescence, acesodyne, sterilization and bacteriostasis, and capability of being quickly absorbed by skin, does not generate strong stimulation to the skin, does not cause injury to subcutaneous tissues, and simultaneously has the functions of moistening the skin, improving the recovery rate of the skin and preventing various skin diseases.
The traditional Chinese medicine extracting solution is obtained by boiling and filtering raw materials, and the raw materials consist of honeysuckle, mint, angelica dahurica, selfheal, houttuynia cordata, asarum, isatis root, gastrodia elata, dendrobe, garden balsam stem, patchouli and macrocyclic triterpenoid saponin, and the components in parts by weight are as follows: 10 parts of honeysuckle; 8 parts of mint; 3 parts of radix angelicae; 6 parts of selfheal; 2 parts of houttuynia cordata; 1 part of asarum; 15 parts of isatis root; 2 parts of gastrodia elata; 4 parts of dendrobium; 3 parts of garden balsam stem; 2 parts of cablin potchouli herb; 8 parts of macrocyclic triterpenoid saponin.
The water-soluble coupling agent comprises carbomer, ethylene diamine tetraacetic acid, organic acid, mica powder, hydroxyethyl cellulose, calcium triethyl diamine tetraacetate, nonylphenol polyoxyethylene ether, histidine, lactic acid, glycerol and distilled water, and comprises the following components in parts by weight: 8 parts of carbomer; 3 parts of ethylene diamine tetraacetic acid; 1 part of organic acid; 2 parts of mica powder; 3 parts of hydroxyethyl cellulose; 4 parts of triethyl diamine tetraacetate; 4 parts of nonylphenol polyoxyethylene ether; 5 parts of histidine; 3 parts of lactic acid; 15 parts of glycerol; and 40 parts of distilled water.
The skin care agent consists of glycerin, saponin essence, a coupling agent, liquid paraffin, essence, collagen, hydroxyethyl cellulose, dibutyl phthalate and deionized water, and comprises the following components in parts by weight: 6 parts of glycerol; 30 parts of saponin essence; 13 parts of a coupling agent; 2 parts of liquid paraffin; 3 parts of essence; 2 parts of collagen; 3 parts of hydroxyethyl cellulose; 3 parts of dibutyl phthalate; 40 parts of deionized water.
A preparation method of traditional Chinese medicine skin disinfectant fluid comprises the following steps:
A. ball milling: respectively putting chlorhexidine acetate, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan and lecithin powder into a ball mill for ball milling treatment, wherein the ball milling particle size is 80 meshes;
B. soaking: putting chlorhexidine acetate, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan and lecithin powder in a box in parts by weight, then adding traditional Chinese medicine extracting solution, PEG400, glycerol, povidone iodine, a water-soluble coupling agent, a skin care agent and plasma water in parts by weight, and soaking for 25 d;
C. and (3) precipitation: pouring the soaked mixed solution into a precipitation box, and precipitating for 20 hours;
D. taking clear liquid: pouring the suspension into a filling machine from the filter screen;
E. filling: filling the clear liquid in the filling machine into a bottle;
F. and packaging and warehousing after the inspection is qualified.
And (C) matching the box body in the step (B) with a heating device, wherein the heating device is an infrared heater, the heating temperature is 30 ℃, and meanwhile, stirring is carried out once every 30 hours in the step (B), and the stirring time is 8 min.
Example two:
a traditional Chinese medicine skin disinfectant fluid is composed of traditional Chinese medicine extracting solution, chlorhexidine acetate, PEG400, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan, glycerol, povidone iodine, lecithin powder, a water-soluble coupling agent, a skin care agent and plasma water, and comprises the following components in parts by weight: 28 parts of a traditional Chinese medicine extracting solution; 5 parts of chlorhexidine acetate; PEG 4007 parts; 3 parts of sodium dodecyl sulfate; 5 parts of polyhexamethylene guanidine hydrochloride; 2 parts of chitosan; 9 parts of glycerol; 12 parts of glycerol; 8 parts of povidone iodine; 5 parts of lecithin powder; 12 parts of a water-soluble coupling agent; 7 parts of a skin care agent; 125 parts of plasma water.
The traditional Chinese medicine extract is used as a raw material, has the advantages of obvious effect, low cost, obvious effects of detumescence, acesodyne, sterilization and bacteriostasis, and capability of being quickly absorbed by skin, does not generate strong stimulation to the skin, does not cause injury to subcutaneous tissues, and simultaneously has the functions of moistening the skin, improving the recovery rate of the skin and preventing various skin diseases.
The traditional Chinese medicine extracting solution is obtained by boiling and filtering raw materials, and the raw materials consist of honeysuckle, mint, angelica dahurica, selfheal, houttuynia cordata, asarum, isatis root, gastrodia elata, dendrobe, garden balsam stem, patchouli and macrocyclic triterpenoid saponin, and the components in parts by weight are as follows: 10-15 parts of honeysuckle; 8-15 parts of mint; 5 parts of radix angelicae; 9 parts of selfheal; 2 parts of houttuynia cordata; 3 parts of asarum; 17 parts of isatis root; 4 parts of gastrodia elata; 7 parts of dendrobium; 5 parts of garden balsam stem; 4 parts of cablin potchouli herb; 10 parts of macrocyclic triterpenoid saponin.
The water-soluble coupling agent comprises carbomer, ethylene diamine tetraacetic acid, organic acid, mica powder, hydroxyethyl cellulose, calcium triethyl diamine tetraacetate, nonylphenol polyoxyethylene ether, histidine, lactic acid, glycerol and distilled water, and comprises the following components in parts by weight: 11 parts of carbomer; 5 parts of ethylene diamine tetraacetic acid; 2 parts of organic acid; 4 parts of mica powder; 6 parts of hydroxyethyl cellulose; 5 parts of triethyl diamine tetraacetate; 7 parts of nonylphenol polyoxyethylene ether; 6 parts of histidine; 5 parts of lactic acid; 20 parts of glycerol; 47 parts of distilled water.
The skin care agent consists of glycerin, saponin essence, a coupling agent, liquid paraffin, essence, collagen, hydroxyethyl cellulose, dibutyl phthalate and deionized water, and comprises the following components in parts by weight: 8 parts of glycerol; 40 parts of saponin essence; 17 parts of a coupling agent; 4 parts of liquid paraffin; 5 parts of essence; 5 parts of collagen; 6 parts of hydroxyethyl cellulose; 6 parts of dibutyl phthalate; 60 parts of deionized water.
A preparation method of traditional Chinese medicine skin disinfectant fluid comprises the following steps:
A. ball milling: respectively putting chlorhexidine acetate, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan and lecithin powder into a ball mill for ball milling treatment, wherein the ball milling particle size is 110 meshes;
B. soaking: putting chlorhexidine acetate, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan and lecithin powder in a box in parts by weight, then adding traditional Chinese medicine extracting solution, PEG400, glycerol, povidone iodine, a water-soluble coupling agent, a skin care agent and plasma water in parts by weight, and soaking for 32 d;
C. and (3) precipitation: pouring the soaked mixed solution into a precipitation box, and precipitating for 25 h;
D. taking clear liquid: pouring the suspension into a filling machine from the filter screen;
E. filling: filling the clear liquid in the filling machine into a bottle;
F. and packaging and warehousing after the inspection is qualified.
And (C) matching the box body in the step (B) with a heating device, wherein the heating device is a graphite furnace, the heating temperature is 40 ℃, and meanwhile, stirring is carried out once every 25 hours in the step (B), and the stirring time is 12 min.
Example three:
a traditional Chinese medicine skin disinfectant fluid is composed of traditional Chinese medicine extracting solution, chlorhexidine acetate, PEG400, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan, glycerol, povidone iodine, lecithin powder, a water-soluble coupling agent, a skin care agent and plasma water, and comprises the following components in parts by weight: 35 parts of traditional Chinese medicine extracting solution; 7 parts of chlorhexidine acetate; 10 parts of PEG 40010; 5 parts of sodium dodecyl sulfate; 7 parts of polyhexamethylene guanidine hydrochloride; 4 parts of chitosan; 12 parts of glycerol; 15 parts of glycerol; 10 parts of povidone iodine; 7 parts of lecithin powder; 15 parts of a water-soluble coupling agent; 10 parts of a skin care agent; 150 parts of plasma water.
The traditional Chinese medicine extract is used as a raw material, has the advantages of obvious effect, low cost, obvious effects of detumescence, acesodyne, sterilization and bacteriostasis, and capability of being quickly absorbed by skin, does not generate strong stimulation to the skin, does not cause injury to subcutaneous tissues, and simultaneously has the functions of moistening the skin, improving the recovery rate of the skin and preventing various skin diseases.
The traditional Chinese medicine extracting solution is obtained by boiling and filtering raw materials, and the raw materials consist of honeysuckle, mint, angelica dahurica, selfheal, houttuynia cordata, asarum, isatis root, gastrodia elata, dendrobe, garden balsam stem, patchouli and macrocyclic triterpenoid saponin, and the components in parts by weight are as follows: 15 parts of honeysuckle; 15 parts of mint; 7 parts of radix angelicae; 12 parts of selfheal; 5 parts of houttuynia cordata; 4 parts of asarum; 22 parts of isatis root; 6 parts of gastrodia elata; 10 parts of dendrobium; 7 parts of garden balsam stem; 5 parts of cablin potchouli herb; and 15 parts of macrocyclic triterpenoid saponin.
The water-soluble coupling agent comprises carbomer, ethylene diamine tetraacetic acid, organic acid, mica powder, hydroxyethyl cellulose, calcium triethyl diamine tetraacetate, nonylphenol polyoxyethylene ether, histidine, lactic acid, glycerol and distilled water, and comprises the following components in parts by weight: 15 parts of carbomer; 7 parts of ethylene diamine tetraacetic acid; 3 parts of organic acid; 5 parts of mica powder; 9 parts of hydroxyethyl cellulose; 6 parts of triethyl diamine tetraacetate; 10 parts of nonylphenol polyoxyethylene ether; 8 parts of histidine; 8 parts of lactic acid; 25 parts of glycerol; 55 parts of distilled water.
The skin care agent consists of glycerin, saponin essence, a coupling agent, liquid paraffin, essence, collagen, hydroxyethyl cellulose, dibutyl phthalate and deionized water, and comprises the following components in parts by weight: 10 parts of glycerol; 50 parts of saponin essence; 20 parts of a coupling agent; 6 parts of liquid paraffin; 7 parts of essence; 8 parts of collagen; 9 parts of hydroxyethyl cellulose; 10 parts of dibutyl phthalate; 80 parts of deionized water.
A preparation method of traditional Chinese medicine skin disinfectant fluid comprises the following steps:
A. ball milling: respectively putting chlorhexidine acetate, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan and lecithin powder into a ball mill for ball milling treatment, wherein the ball milling particle size is 80-150 meshes;
B. soaking: putting chlorhexidine acetate, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan and lecithin powder in a box in parts by weight, then adding traditional Chinese medicine extracting solution, PEG400, glycerol, povidone iodine, a water-soluble coupling agent, a skin care agent and plasma water in parts by weight, and soaking for 40 d;
C. and (3) precipitation: pouring the soaked mixed solution into a precipitation box, and precipitating for 30 hours;
D. taking clear liquid: pouring the suspension into a filling machine from the filter screen;
E. filling: filling the clear liquid in the filling machine into a bottle;
F. and packaging and warehousing after the inspection is qualified.
And (C) matching the box body in the step (B) with a heating device, wherein the heating device is an electron beam heater, the heating temperature is 50 ℃, and meanwhile, stirring is carried out once every 20 hours in the step (B), and the stirring time is 15 min.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. A traditional Chinese medicine skin disinfectant fluid is characterized in that: the disinfectant fluid consists of traditional Chinese medicine extracting solution, chlorhexidine acetate, PEG400, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan, glycerol, povidone iodine, lecithin powder, a water-soluble coupling agent, a skin care agent and plasma water, and comprises the following components in parts by weight: 20-35 parts of traditional Chinese medicine extracting solution; 3-7 parts of chlorhexidine acetate; 5-10 parts of PEG 400; 2-5 parts of sodium dodecyl sulfate; 3-7 parts of polyhexamethylene guanidine hydrochloride; 1-4 parts of chitosan; 6-12 parts of glycerol; 8-15 parts of glycerol; 5-10 parts of povidone iodine; 3-7 parts of lecithin powder; 10-15 parts of a water-soluble coupling agent; 4-10 parts of a skin care agent; 100 portions and 150 portions of plasma water.
2. The traditional Chinese medicine skin disinfectant fluid according to claim 1, which is characterized in that: the traditional Chinese medicine extracting solution is obtained by steaming and filtering raw materials, and the raw materials consist of honeysuckle, mint, angelica dahurica, selfheal, houttuynia cordata, asarum, isatis root, gastrodia elata, dendrobe, garden balsam stem, patchouli and macrocyclic triterpenoid saponin, and the traditional Chinese medicine extracting solution comprises the following components in parts by weight: 10-15 parts of honeysuckle; 8-15 parts of mint; 3-7 parts of radix angelicae; 6-12 parts of selfheal; 2-5 parts of houttuynia cordata; 1-4 parts of asarum; 15-22 parts of isatis root; 2-6 parts of gastrodia elata; 4-10 parts of dendrobium; 3-7 parts of garden balsam stem; 2-5 parts of cablin potchouli herb; 8-15 parts of macrocyclic triterpenoid saponin.
3. The traditional Chinese medicine skin disinfectant fluid according to claim 1, which is characterized in that: the water-soluble coupling agent comprises carbomer, ethylene diamine tetraacetic acid, organic acid, mica powder, hydroxyethyl cellulose, calcium triethyl diamine tetraacetate, nonylphenol polyoxyethylene ether, histidine, lactic acid, glycerol and distilled water, and comprises the following components in parts by weight: 8-15 parts of carbomer; 3-7 parts of ethylene diamine tetraacetic acid; 1-3 parts of organic acid; 2-5 parts of mica powder; 3-9 parts of hydroxyethyl cellulose; 4-6 parts of triethyl diamine tetraacetate calcium; 4-10 parts of nonylphenol polyoxyethylene ether; 5-8 parts of histidine; 3-8 parts of lactic acid; 15-25 parts of glycerol; 40-55 parts of distilled water.
4. The traditional Chinese medicine skin disinfectant fluid according to claim 1, which is characterized in that: the skin care agent is composed of glycerol, saponin essence, a coupling agent, liquid paraffin, essence, collagen, hydroxyethyl cellulose, dibutyl phthalate and deionized water, and comprises the following components in parts by weight: 6-10 parts of glycerol; 30-50 parts of saponin essence; 13-20 parts of a coupling agent; 2-6 parts of liquid paraffin; 3-7 parts of essence; 2-8 parts of collagen; 3-9 parts of hydroxyethyl cellulose; 3-10 parts of dibutyl phthalate; 40-80 parts of deionized water.
5. A preparation method of traditional Chinese medicine skin disinfectant fluid is characterized by comprising the following steps: the preparation method comprises the following steps:
A. ball milling: respectively putting chlorhexidine acetate, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan and lecithin powder into a ball mill for ball milling treatment, wherein the ball milling particle size is 80-150 meshes;
B. soaking: putting chlorhexidine acetate, sodium dodecyl sulfate, polyhexamethylene guanidine hydrochloride, chitosan and lecithin powder in a box body in parts by weight, then adding traditional Chinese medicine extracting solution, PEG400, glycerol, povidone iodine, a water-soluble coupling agent, a skin care agent and plasma water in parts by weight, and soaking for 25-40 d;
C. and (3) precipitation: pouring the soaked mixed solution into a precipitation box, and precipitating for 20-30 h;
D. taking clear liquid: pouring the suspension into a filling machine from the filter screen;
E. filling: filling the clear liquid in the filling machine into a bottle;
F. and packaging and warehousing after the inspection is qualified.
6. The method for preparing a Chinese medicinal skin disinfectant fluid according to claim 5, wherein the method comprises the following steps: and B, matching the box body in the step B with a heating device, wherein the heating device is an infrared heater, a graphite furnace or an electron beam heater, the heating temperature is 30-50 ℃, and meanwhile, stirring is carried out once every 20-30h in the step B, and the stirring time is 8-15 min.
CN202010246751.7A 2020-03-31 2020-03-31 Traditional Chinese medicine skin disinfectant fluid and preparation method thereof Pending CN111588808A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104435607A (en) * 2014-11-28 2015-03-25 成都顺发消洗科技有限公司 Chinese herbal medicine skin mucosa disinfectant
CN105412879A (en) * 2015-12-21 2016-03-23 青岛拓联信息技术有限公司 Traditional Chinese herbal medicine disinfectant fluid
CN105497460A (en) * 2016-02-25 2016-04-20 杨甫进 Disinfectant for disinfecting skins

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104435607A (en) * 2014-11-28 2015-03-25 成都顺发消洗科技有限公司 Chinese herbal medicine skin mucosa disinfectant
CN105412879A (en) * 2015-12-21 2016-03-23 青岛拓联信息技术有限公司 Traditional Chinese herbal medicine disinfectant fluid
CN105497460A (en) * 2016-02-25 2016-04-20 杨甫进 Disinfectant for disinfecting skins

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