CN111569034A - External traditional Chinese medicine for treating arthralgia and preparation method thereof - Google Patents
External traditional Chinese medicine for treating arthralgia and preparation method thereof Download PDFInfo
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Abstract
The invention relates to the field of traditional Chinese medicine external preparations, in particular to an external traditional Chinese medicine for treating arthralgia and a preparation method thereof. The formula is mainly characterized by wild nature of pungent and warm drugs, treats the defect of extreme cold, has the effects of warming and dredging cold, promoting qi and blood circulation, dredging channels and collaterals, relieving exterior syndrome and cold, removing blood stasis and relieving pain, and is suitable for treating soft tissue injury, limb dysfunction after fracture healing, shoulder, neck, lumbocrural pain, knee joint pain and the like.
Description
Technical Field
The invention relates to the field of traditional Chinese medicine external preparations, in particular to an external traditional Chinese medicine for treating arthralgia and a preparation method thereof.
Background
Wind-damp arthralgia is a disease caused by wind-cold-dampness, mainly manifested by pain, soreness, numbness, heaviness of limbs and joints, and movement disorder. The main symptoms of rheumatic arthralgia are joint pain, morning stiffness, joint swelling and tenderness, joint swelling and pain, joint deformity and dysfunction. The cold pain, which is caused by cold in the joints, is a problem that no good method is available in the medical field so far. The syndrome of arthralgia after injury is the predicate of traditional Chinese medicine. It is caused by trauma (contusion, sprain, strain), injury of body surface tissue structure, damage of joint fence, wind-cold-dampness pathogen entering due to deficiency, blood stasis, cold and wind-dampness combining into arthralgia, entering into joint, blocking channels and collaterals, stagnation of qi and blood, and obstruction of arthralgia, so it is painful. The joint of the injury is affected by the change of weather, and the pain is relieved by warmth and increased by coldness, so the patient is said to have the feeling of cold entering the bone and be in a bad sense.
Disclosure of Invention
In order to solve the problems, the invention provides an external traditional Chinese medicine for treating arthralgia and a preparation method thereof.
In order to achieve the purpose, the invention adopts the technical scheme that:
a topical Chinese medicine for the treatment of rheumatalgia is prepared from semen Strychni, radix Aconiti Kusnezoffii, radix Aconiti, rhizoma arisaematis, rhizoma Pinelliae, herba asari, herba Speranskiae Tuberculatae, Curcuma rhizome, Olibanum, Myrrha, lignum sappan, yellow wine and appropriate amount of adjuvants by mixing.
Further, the external traditional Chinese medicine is cream-shaped and is mainly prepared from the following raw materials in parts by weight:
3-4 parts of nux vomica, 1.5-2 parts of raw kusnezoff monkshood root, 1-2 parts of raw radix aconiti, 2-3 parts of raw arisaema consanguineum schott, 2-3 parts of raw pinellia ternate, 1.5-2 parts of asarum, 2-3 parts of garden balsam stem, 2-3 parts of turmeric, 2-3 parts of frankincense, 2-3 parts of myrrh, 1.2-1.5 parts of sappan wood and 2-3 parts of yellow wine.
Furthermore, the auxiliary materials at least comprise azone, vaseline and yellow wine.
Preferably, the feed is mainly prepared from the following raw materials in parts by weight:
3 parts of nux vomica, 1.5 parts of raw kusnezoff monkshood root, 1 part of raw common monkshood mother root, 2 parts of raw arisaema, 2 parts of raw pinellia tuber, 1.5 parts of manchurian wildginger, 2 parts of garden balsam stem, 2 parts of turmeric, 2 parts of frankincense, 2 parts of myrrh, 1.2 parts of sappan wood and 2 parts of yellow wine.
Preferably, the feed is mainly prepared from the following raw materials in parts by weight:
4 parts of nux vomica, 2 parts of raw kusnezoff monkshood root, 2 parts of raw common monkshood mother root, 3 parts of raw arisaema, 3 parts of raw pinellia tuber, 2 parts of manchurian wildginger, 3 parts of garden balsam stem, 3 parts of turmeric, 3 parts of frankincense, 3 parts of myrrh, 1.5 parts of sappan wood and 3 parts of yellow wine.
Preferably, the feed is mainly prepared from the following raw materials in parts by weight:
3.5 parts of nux vomica, 1.75 parts of raw kusnezoff monkshood root, 1.5 parts of raw radix aconiti, 2.5 parts of raw arisaema consanguineum schott, 2.5 parts of raw pinellia ternate, 1.75 parts of asarum, 2.5 parts of garden balsam stem, 2.5 parts of turmeric, 2.5 parts of frankincense, 2.5 parts of myrrh, 1.35 parts of sappan wood and 2.5 parts of yellow wine.
The invention also provides a preparation method of the external traditional Chinese medicine for treating arthralgia, which comprises the following steps:
s1, weighing the following components in parts by weight: 3-4 parts of nux vomica, 1.5-2 parts of raw kusnezoff monkshood root, 1-2 parts of raw radix aconiti, 2-3 parts of raw arisaema consanguineum schott, 2-3 parts of raw pinellia ternate, 1.5-2 parts of asarum, 2-3 parts of garden balsam stem, 2-3 parts of turmeric, 2-3 parts of frankincense, 2-3 parts of myrrh, 1.2-1.5 parts of sappan wood and 2-3 parts of yellow wine;
s2, washing the weighed semen qianzi, raw radix aconiti kusnezoffii, raw radix aconiti, raw rhizoma arisaematis, raw pinellia ternate, asarum, garden balsam stem, turmeric, frankincense, myrrh and sappan wood, crushing to 80-120 meshes, and mixing with yellow wine and stirring uniformly to obtain traditional Chinese medicine powder for later use;
s3, weighing the following components in percentage by mass: mixing vaseline 14.3% and distilled water 40%, stirring and dissolving to obtain phase A;
s4, weighing the following components in percentage by mass: 1% of azone, 8% of glycerol and 29.5% of distilled water are uniformly mixed to be used as a phase B for standby;
s5, weighing 7.2% of the traditional Chinese medicine powder according to the mass ratio, dissolving in the phase B, heating to 80 ℃, slowly stirring, and uniformly mixing to obtain a phase C;
s6, slowly adding the phase C into the phase A, stirring at a high speed for 3-5 min, and uniformly mixing; cooling to 65-75 ℃, slowly stirring, and defoaming; continuously cooling to 40-50 ℃, continuously and slowly stirring, and stopping stirring after cooling to room temperature;
s7, grinding the mixture until the particle fineness is less than 5 mu m, and inputting the mixture into a high-speed stirrer to carry out high-speed strong stirring to obtain an emulsion semi-finished product;
s8, carrying out vacuum degassing treatment on the obtained milky semi-finished product, filling and sterilizing to obtain the product.
The formula is mainly characterized by wild nature of pungent and warm drugs, treats the defect of extreme cold, has the effects of warming and dredging cold, promoting qi and blood circulation, dredging channels and collaterals, relieving exterior syndrome and cold, removing blood stasis and relieving pain, and is suitable for treating soft tissue injury, limb dysfunction after fracture healing, shoulder, neck, lumbocrural pain, knee joint pain and the like.
The cream is convenient to apply, can promote the absorption of the medicine, reduce the stimulation to the skin and avoid the rash and the like caused by plaster application.
Detailed Description
The present invention will be described in detail with reference to specific examples. The following examples will assist those skilled in the art in further understanding the invention, but are not intended to limit the invention in any way. It should be noted that variations and modifications can be made by persons skilled in the art without departing from the spirit of the invention. All falling within the scope of the present invention.
Example 1
An external traditional Chinese medicine for treating arthralgia is prepared by the following steps:
s1, weighing the following components in parts by weight: 3 parts of nux vomica, 1.5 parts of raw kusnezoff monkshood root, 1 part of raw common monkshood mother root, 2 parts of raw arisaema, 2 parts of raw pinellia ternate, 1.5 parts of manchurian wildginger, 2 parts of garden balsam stem, 2 parts of turmeric, 2 parts of frankincense, 2 parts of myrrh, 1.2 parts of sappan wood and 2 parts of yellow wine;
s2, washing the weighed semen qianzi, raw radix aconiti kusnezoffii, raw radix aconiti, raw rhizoma arisaematis, raw pinellia ternate, asarum, garden balsam stem, turmeric, frankincense, myrrh and sappan wood, crushing to 80-120 meshes, and mixing with yellow wine and stirring uniformly to obtain traditional Chinese medicine powder for later use;
s3, weighing the following components in percentage by mass: mixing vaseline 14.3% and distilled water 40%, stirring and dissolving to obtain phase A;
s4, weighing the following components in percentage by mass: 1% of azone, 8% of glycerol and 29.5% of distilled water are uniformly mixed to be used as a phase B for standby;
s5, weighing 7.2% of the traditional Chinese medicine powder according to the mass ratio, dissolving in the phase B, heating to 80 ℃, slowly stirring, and uniformly mixing to obtain a phase C;
s6, slowly adding the phase C into the phase A, stirring at a high speed for 3-5 min, and uniformly mixing; cooling to 65-75 ℃, slowly stirring, and defoaming; continuously cooling to 40-50 ℃, continuously and slowly stirring, and stopping stirring after cooling to room temperature;
s7, grinding the mixture until the particle fineness is less than 5 mu m, and inputting the mixture into a high-speed stirrer to carry out high-speed strong stirring to obtain an emulsion semi-finished product;
s8, carrying out vacuum degassing treatment on the obtained milky semi-finished product, filling and sterilizing to obtain the product.
Example 2
An external traditional Chinese medicine for treating arthralgia is prepared by the following steps:
s1, weighing the following components in parts by weight: 4 parts of nux vomica, 2 parts of raw kusnezoff monkshood root, 2 parts of raw common monkshood mother root, 3 parts of raw arisaema, 3 parts of raw pinellia tuber, 2 parts of manchurian wildginger, 3 parts of garden balsam stem, 3 parts of turmeric, 3 parts of frankincense, 3 parts of myrrh, 1.5 parts of sappan wood and 3 parts of yellow wine;
s2, washing the weighed semen qianzi, raw radix aconiti kusnezoffii, raw radix aconiti, raw rhizoma arisaematis, raw pinellia ternate, asarum, garden balsam stem, turmeric, frankincense, myrrh and sappan wood, crushing to 80-120 meshes, and mixing with yellow wine and stirring uniformly to obtain traditional Chinese medicine powder for later use;
s3, weighing the following components in percentage by mass: mixing vaseline 14.3% and distilled water 40%, stirring and dissolving to obtain phase A;
s4, weighing the following components in percentage by mass: 1% of azone, 8% of glycerol and 29.5% of distilled water are uniformly mixed to be used as a phase B for standby;
s5, weighing 7.2% of the traditional Chinese medicine powder according to the mass ratio, dissolving in the phase B, heating to 80 ℃, slowly stirring, and uniformly mixing to obtain a phase C;
s6, slowly adding the phase C into the phase A, stirring at a high speed for 3-5 min, and uniformly mixing; cooling to 65-75 ℃, slowly stirring, and defoaming; continuously cooling to 40-50 ℃, continuously and slowly stirring, and stopping stirring after cooling to room temperature;
s7, grinding the mixture until the particle fineness is less than 5 mu m, and inputting the mixture into a high-speed stirrer to carry out high-speed strong stirring to obtain an emulsion semi-finished product;
s8, carrying out vacuum degassing treatment on the obtained milky semi-finished product, filling and sterilizing to obtain the product.
Example 3
An external traditional Chinese medicine for treating arthralgia is prepared by the following steps:
s1, weighing the following components in parts by weight: 3.5 parts of nux vomica, 1.75 parts of raw kusnezoff monkshood root, 1.5 parts of raw radix aconiti, 2.5 parts of raw arisaema, 2.5 parts of raw pinellia ternate, 1.75 parts of asarum, 2.5 parts of garden balsam stem, 2.5 parts of turmeric, 2.5 parts of frankincense, 2.5 parts of myrrh, 1.35 parts of sappan wood and 2.5 parts of yellow wine;
s2, washing the weighed semen qianzi, raw radix aconiti kusnezoffii, raw radix aconiti, raw rhizoma arisaematis, raw pinellia ternate, asarum, garden balsam stem, turmeric, frankincense, myrrh and sappan wood, crushing to 80-120 meshes, and mixing with yellow wine and stirring uniformly to obtain traditional Chinese medicine powder for later use;
s3, weighing the following components in percentage by mass: mixing vaseline 14.3% and distilled water 40%, stirring and dissolving to obtain phase A;
s4, weighing the following components in percentage by mass: 1% of azone, 8% of glycerol and 29.5% of distilled water are uniformly mixed to be used as a phase B for standby;
s5, weighing 7.2% of the traditional Chinese medicine powder according to the mass ratio, dissolving in the phase B, heating to 80 ℃, slowly stirring, and uniformly mixing to obtain a phase C;
s6, slowly adding the phase C into the phase A, stirring at a high speed for 3-5 min, and uniformly mixing; cooling to 65-75 ℃, slowly stirring, and defoaming; continuously cooling to 40-50 ℃, continuously and slowly stirring, and stopping stirring after cooling to room temperature;
s7, grinding the mixture until the particle fineness is less than 5 mu m, and inputting the mixture into a high-speed stirrer to carry out high-speed strong stirring to obtain an emulsion semi-finished product;
s8, carrying out vacuum degassing treatment on the obtained milky semi-finished product, filling and sterilizing to obtain the product.
Test examples
100 recorded patients suffering from rheumatic arthralgia who try the product are 45 men and 55 women, and the patients are 26 years old and 72 years old at the minimum; 30 cases of arthritis and rheumatoid arthritis; knee joint and leg joint pain 20 cases; 32 cases of lumbago; shoulder and neck pain 18 cases. Treatment with the formulation prepared in example 3; when in use, the medicament is uniformly smeared on an affected part for 1 time every day, 10 times are taken as a course of treatment, 3 courses of treatment are continuously used, the improvement conditions of relevant symptoms and physical signs of rheumatic arthralgia of a test user are observed, and the test effect is evaluated according to the following standards:
controlling the disease condition: after 3 courses of treatment, the symptoms such as pain disappear, the joint moves normally, and other objective examination indexes are basically normal;
the effect is shown: after 3 courses of treatment, the symptoms such as pain disappear, joint movement is not limited, and other objective examination indexes are obviously improved;
the method has the following advantages: after 3 courses of treatment, the symptoms such as pain and the like basically disappear, the joint movement is slightly limited, and other objective examination indexes are improved;
and (4) invalidation: after 3 courses of treatment, the symptoms such as pain and joint movement are not obviously improved, and other objective examination indexes are not improved.
The experimental results are as follows: the medicament provided by the invention has good relieving and treating effects on rheumatic arthralgia. Wherein the effective rate for arthritis and rheumatoid arthritis is 80%, the effective rate for shoulder and neck pain is 83.3%, the effective rate for knee joint and leg joint pain is 90%, and the effective rate for lumbago is 75%.
The foregoing description of specific embodiments of the present invention has been presented. It is to be understood that the present invention is not limited to the specific embodiments described above, and that various changes or modifications may be made by one skilled in the art within the scope of the appended claims without departing from the spirit of the invention. The embodiments and features of the embodiments of the present application may be combined with each other arbitrarily without conflict.
Claims (7)
1. An external traditional Chinese medicine for treating arthralgia is characterized in that: is prepared from semen Strychni, radix Aconiti Kusnezoffii, radix Aconiti, rhizoma arisaematis, rhizoma Pinelliae, herba asari, herba Speranskiae Tuberculatae, Curcuma rhizome, Olibanum, Myrrha, lignum sappan, yellow wine and appropriate amount of adjuvants.
2. The external traditional Chinese medicine for treating arthralgia according to claim 1, which is characterized in that: the external traditional Chinese medicine is cream-shaped and mainly prepared from the following raw materials in parts by weight:
3-4 parts of nux vomica, 1.5-2 parts of raw kusnezoff monkshood root, 1-2 parts of raw radix aconiti, 2-3 parts of raw arisaema consanguineum schott, 2-3 parts of raw pinellia ternate, 1.5-2 parts of asarum, 2-3 parts of garden balsam stem, 2-3 parts of turmeric, 2-3 parts of frankincense, 2-3 parts of myrrh, 1.2-1.5 parts of sappan wood and 2-3 parts of yellow wine.
3. The external traditional Chinese medicine for treating arthralgia according to claim 1, which is characterized in that: the auxiliary materials at least comprise azone, vaseline and yellow wine.
4. The external traditional Chinese medicine for treating arthralgia according to claim 2, which is characterized in that: the health-care food is mainly prepared from the following raw materials in parts by weight:
3 parts of nux vomica, 1.5 parts of raw kusnezoff monkshood root, 1 part of raw common monkshood mother root, 2 parts of raw arisaema, 2 parts of raw pinellia tuber, 1.5 parts of manchurian wildginger, 2 parts of garden balsam stem, 2 parts of turmeric, 2 parts of frankincense, 2 parts of myrrh, 1.2 parts of sappan wood and 2 parts of yellow wine.
5. The external traditional Chinese medicine for treating arthralgia according to claim 2, which is characterized in that: the health-care food is mainly prepared from the following raw materials in parts by weight:
4 parts of nux vomica, 2 parts of raw kusnezoff monkshood root, 2 parts of raw common monkshood mother root, 3 parts of raw arisaema, 3 parts of raw pinellia tuber, 2 parts of manchurian wildginger, 3 parts of garden balsam stem, 3 parts of turmeric, 3 parts of frankincense, 3 parts of myrrh, 1.5 parts of sappan wood and 3 parts of yellow wine.
6. The external traditional Chinese medicine for treating arthralgia according to claim 2, which is characterized in that: the health-care food is mainly prepared from the following raw materials in parts by weight:
3.5 parts of nux vomica, 1.75 parts of raw kusnezoff monkshood root, 1.5 parts of raw radix aconiti, 2.5 parts of raw arisaema consanguineum schott, 2.5 parts of raw pinellia ternate, 1.75 parts of asarum, 2.5 parts of garden balsam stem, 2.5 parts of turmeric, 2.5 parts of frankincense, 2.5 parts of myrrh, 1.35 parts of sappan wood and 2.5 parts of yellow wine.
7. A preparation method of an external traditional Chinese medicine for treating arthralgia is characterized by comprising the following steps: the method comprises the following steps:
s1, weighing the following components in parts by weight: 3-4 parts of nux vomica, 1.5-2 parts of raw kusnezoff monkshood root, 1-2 parts of raw radix aconiti, 2-3 parts of raw arisaema consanguineum schott, 2-3 parts of raw pinellia ternate, 1.5-2 parts of asarum, 2-3 parts of garden balsam stem, 2-3 parts of turmeric, 2-3 parts of frankincense, 2-3 parts of myrrh, 1.2-1.5 parts of sappan wood and 2-3 parts of yellow wine;
s2, washing the weighed semen qianzi, raw radix aconiti kusnezoffii, raw radix aconiti, raw rhizoma arisaematis, raw pinellia ternate, asarum, garden balsam stem, turmeric, frankincense, myrrh and sappan wood, crushing to 80-120 meshes, and mixing with yellow wine and stirring uniformly to obtain traditional Chinese medicine powder for later use;
s3, weighing the following components in percentage by mass: mixing vaseline 14.3% and distilled water 40%, stirring and dissolving to obtain phase A;
s4, weighing the following components in percentage by mass: 1% of azone, 8% of glycerol and 29.5% of distilled water are uniformly mixed to be used as a phase B for standby;
s5, weighing 7.2% of the traditional Chinese medicine powder according to the mass ratio, dissolving in the phase B, heating to 80 ℃, slowly stirring, and uniformly mixing to obtain a phase C;
s6, slowly adding the phase C into the phase A, stirring at a high speed for 3-5 min, and uniformly mixing; cooling to 65-75 ℃, slowly stirring, and defoaming; continuously cooling to 40-50 ℃, continuously and slowly stirring, and stopping stirring after cooling to room temperature;
s7, grinding the mixture until the particle fineness is less than 5 mu m, and inputting the mixture into a high-speed stirrer to carry out high-speed strong stirring to obtain an emulsion semi-finished product;
s8, carrying out vacuum degassing treatment on the obtained milky semi-finished product, filling and sterilizing to obtain the product.
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