CN107320584B - A topical medicine for treating rheumatoid diseases and preparation method thereof - Google Patents
A topical medicine for treating rheumatoid diseases and preparation method thereof Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
- A61K36/126—Drynaria
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/237—Notopterygium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Abstract
The invention discloses an external medicine for treating rheumatoid disease and a preparation method thereof, wherein the formula comprises the following fresh medicinal materials and dry medicinal materials in parts by weight: 20-32 parts of vitex negundo; 18-20 parts of cinnamomum kanehirae leaves; 16-22 parts of Tuniuqi; 3-8 parts of honeysuckle branches; 8-15 parts of vitis amurensis; dry medicinal materials: 2-5 parts of notopterygium root; 3-6 parts of rhizoma cibotii; 2-5 parts of rhizoma drynariae; 3-8 parts of oyster shell, the formula has scientific compatibility, and all the components supplement each other. The external medicine is prepared into liquid medicine after medicinal material preparation, sealing, leaching, heating and filtering, is used for treating rheumatoid arthritis, has targeted active ingredients in the liquid medicine, can change stiffness, resist atrophy, soften veins and vessels, promote qi and blood circulation and resist rheumatic factors, can be directly applied externally in the treatment process, is simple, convenient and safe, has no side effect, is not easy to relapse, and achieves the noninvasive reversible healing effect. Provides a new medicine selection for clinic.
Description
Technical Field
The invention relates to a Chinese herbal medicine composition formula, in particular to an external medicine for treating rheumatoid diseases and a preparation method thereof.
Background
At present, the rheumatic arthritis and the rheumatoid arthritis are common chronic and stubborn common diseases and frequently encountered diseases. The clinical manifestations are joint swelling and pain or wandering pain, numbness of limbs, joint deformation, movement obstruction, some even life-long residual wastes, and serious harm to people's health. Such patients are currently on the rise. The early stage mainly comprises synovium inflammation, synovium congestion, swelling and fibrin exudation to form joint effusion, typical inflammatory cell infiltration is carried out in the synovium, then joint cartilage and bone tissues are involved, finally, the joint is strong and straight, the joint of a patient shows red, swollen, hot, painful and movement disorder, joint deformity is more and more obvious, rheumatoid factors of the patient are positive, and X-ray examination shows obvious abnormal expression.
Rheumatoid arthritis is a synovitis-based joint pathology caused by an autoimmune response caused by several infectious diseases. The treatment of rheumatoid arthritis in western medicine is mainly oral medication, salicylic acid preparation such as aspirin is the first choice, and indomethacin and the like are the second choice, and the operation treatment can be carried out on patients in advanced stage.
In summary, no specific therapy is available in the aspect of treating rheumatism and rheumatoid diseases, so the inventor of the present invention strives to develop a traditional Chinese medicine external patch for treating both symptoms and root causes of the disease.
Disclosure of Invention
In view of the above, the invention aims to provide a reversible non-invasive externally applied medicine for treating rheumatoid diseases and a preparation method thereof, wherein the medicine has the effects of clearing and activating the channels and collaterals, promoting blood circulation to remove blood stasis, dispelling wind and removing dampness.
In order to achieve the purpose, the technical scheme of the invention is as follows:
an external medicine for treating rheumatoid diseases is prepared from fresh medicinal materials and dry medicinal materials, wherein the fresh medicinal materials and the dry medicinal materials are correspondingly prepared from the following components in parts by weight:
fresh medicinal materials:
20-32 parts of vitex negundo;
18-20 parts of cinnamomum kanehirae leaves;
16-22 parts of Tuniuqi;
3-8 parts of honeysuckle branches;
8-15 parts of vitis amurensis;
(II) dry medicinal materials:
2-5 parts of notopterygium root;
3-6 parts of rhizoma cibotii;
2-5 parts of rhizoma drynariae;
3-8 parts of oyster shells.
Further, a method for preparing an external medicine for treating rheumatoid disease, comprising the steps of:
(1) preparing medicinal materials: respectively crushing dry medicinal materials of notopterygium root, east Asian tree fern rhizome, drynaria rhizome and oyster shell into sawdust, and filling the components into a container according to the corresponding weight parts of the formula for later use;
(2) sealing and leaching: adding rice wine with the alcohol concentration of 50-60% Vol into a container according to the weight part ratio, wherein the ratio of the total amount of the fresh medicinal materials and the dry medicinal materials to the rice wine is as follows: 1: (2.0-2.8), completely soaking the medicinal materials in rice wine, further sealing the container at the normal temperature of 20-30 ℃ for 2-3 months, taking out the mixed liquid of the medicine residues and the leaching liquor into a pot when the clear liquid in the container is in the color of strong coffee, and waiting for boiling;
(3) the liquid medicine is prepared: and (3) heating in an open manner, boiling the open pot filled with the mixed solution by using a strong fire, then decocting for 2-2.5 hours by using a medium fire until the volume of the mixed solution is concentrated to 65-75% of the initial volume before heating, then stopping heating, and filtering by using sterilized gauze to remove medicine residues to obtain clear liquid medicine with the color of strong coffee for later use.
An external medicine for treating rheumatoid diseases is prepared from fresh medicinal materials and dry medicinal materials in parts by weight:
fresh medicinal materials:
25 parts of vitex negundo;
25 parts of cinnamomum kanehirae leaves;
20 parts of Tuniuqi;
5 parts of honeysuckle branches;
10 parts of vitis amurensis;
(II) dry medicinal materials:
notopterygium root 3 parts;
4 parts of rhizoma cibotii;
3 parts of rhizoma drynariae;
5 parts of oyster shell.
Further, a method for preparing an external medicine for treating rheumatoid disease, comprising the steps of:
(1) preparing medicinal materials: picking and cleaning fresh medicinal materials including vitex negundo, cinnamomum kanehirae, radix achyranthis bidentatae, honeysuckle branches and vitis vinifera, and naturally airing the surface moisture of the fresh medicinal materials; meanwhile, dry medicinal materials of notopterygium root, east Asian tree fern rhizome, drynaria rhizome and oyster shell are respectively crushed into sawdust, and the components are put into a container according to the corresponding weight parts of the formula for standby;
(2) sealing and leaching: adding rice wine with the alcohol concentration of 50-60% Vol into a container according to the weight part ratio, wherein the ratio of the total amount of the fresh medicinal materials and the dry medicinal materials to the rice wine is as follows: 1: (2.0-2.8), completely soaking the medicinal materials in rice wine, further sealing the container at the normal temperature of 20-30 ℃ for 2-3 months, taking out the mixed liquid of the medicine residues and the leaching liquor into a pot when the clear liquid in the container is in the color of strong coffee, and waiting for boiling;
(3) the liquid medicine is prepared: and (3) heating in an open manner, boiling the open pot filled with the mixed solution by using a strong fire, then decocting for 2-2.5 hours by using a medium fire until the volume of the mixed solution is concentrated to 65-75% of the initial volume before heating, then stopping heating, and filtering by using sterilized gauze to remove medicine residues to obtain clear liquid medicine with the color of strong coffee for later use.
The use method of the liquid medicine obtained in the step (3) is as follows:
wetting the medical cotton sheet with the liquid medicine, covering the affected part with the medical cotton, covering with a preservative film, heating to 40 deg.C with a thermotherapy device, maintaining the temperature at 40 deg.C for 60-90 min, and stopping treatment.
After the technical scheme is adopted, the external medicine for treating rheumatoid diseases is composed of fresh medicinal materials including 20-32 parts of vitex negundo, 18-20 parts of cinnamomum kanehirae, 16-22 parts of rhizoma smilacis glabrae, 3-8 parts of honeysuckle branches and 8-15 parts of vitis vinifera, and dry medicinal materials including 2-5 parts of notopterygium root, 3-6 parts of rhizoma cibotii, 2-5 parts of rhizoma drynariae and 3-8 parts of oyster shell. Wherein, the vitex is bitter in taste, warm in nature and non-toxic, and can remove the cold and heat between bones, promote stomach qi circulation, relieve cough and dyspnea; the Cinnamomum kanehirae Hayata leaf contains triterpenes and has the function of activating nerve cell growth capacity; tuniu seven is pungent in flavor and mild in nature, and can dispel wind, dredge collaterals, dissipate blood stasis and relieve pain; the honeysuckle branches are sweet in taste and cold in nature and are used for clearing away heat and toxic materials, dispelling wind and dredging collaterals; the vitis amurensis is sweet and smooth and can relax muscles and tendons and strengthen bones; notopterygii rhizoma has warm nature and cold and dampness eliminating effects, and can be used for treating upper limb rheumatalgia; rhizoma Cibotii is bitter and sweet in taste and warm in nature, and can be used for treating rheumatic arthralgia, soreness and weakness of waist and knees and weakness of lower limbs; rhizoma Drynariae is bitter in taste, warm in nature, and has effects of invigorating kidney, promoting blood circulation, and stopping bleeding, and can be used for treating kidney deficiency, chronic diarrhea, lumbago, and rheumatalgia; oyster shell mainly contains inorganic components such as calcium carbonate, and has effects of tranquilizing mind, suppressing yang hyperactivity, nourishing yin, softening and resolving hard mass, astringing and inducing astringency. The formula of the invention has scientific compatibility, and the components supplement each other. The effective components in the liquid medicine prepared by the invention have pertinence, can change rigidity, resist atrophy, soften tendon and vessel vessels, promote qi and blood circulation and resist rheumatism factors, can be directly externally applied in the treatment process, is simple, convenient and safe, has no side effect, is not easy to relapse, and achieves the non-invasive reversible healing effect. Provides a new medicine selection for clinic.
Detailed Description
In order to further explain the technical solution of the present invention, the present invention is explained in detail by the following specific examples.
Preparation of liquid medicine
The formula of the external medicine for treating rheumatoid disease comprises a fresh medicinal material and a dry medicinal material, wherein the fresh medicinal material and the dry medicinal material are correspondingly composed of the following components in parts by weight:
fresh medicinal materials:
20-32 parts of vitex negundo;
18-20 parts of cinnamomum kanehirae leaves;
16-22 parts of Tuniuqi;
3-8 parts of honeysuckle branches;
8-15 parts of vitis amurensis;
(II) dry medicinal materials:
2-5 parts of notopterygium root;
3-6 parts of rhizoma cibotii;
2-5 parts of rhizoma drynariae;
3-8 parts of oyster shells.
The dosage of the above components of the external medicine of the invention can be adjusted adaptively according to the difference of different individuals, and the dosage can be controlled within the range of the above weight parts.
As a preferred embodiment, the fresh medicinal materials and the dry medicinal materials respectively comprise the following components in parts by weight:
fresh medicinal materials:
25 parts of vitex negundo;
25 parts of cinnamomum kanehirae leaves;
20 parts of Tuniuqi;
5 parts of honeysuckle branches;
10 parts of vitis amurensis;
(II) dry medicinal materials:
notopterygium root 3 parts;
4 parts of rhizoma cibotii;
3 parts of rhizoma drynariae;
5 parts of oyster shell.
A topical medicine for treating rheumatoid diseases is prepared by the following steps:
(1) preparing medicinal materials: picking and cleaning fresh medicinal materials including vitex negundo, cinnamomum kanehirae, radix achyranthis bidentatae, honeysuckle branches and vitis vinifera, and naturally airing the surface moisture of the fresh medicinal materials; simultaneously, respectively crushing dry medicinal materials of notopterygium root, east Asian tree fern rhizome, drynaria rhizome and oyster shell into sawdust, and filling 25 parts of dried oyster, 25 parts of cinnamomum kanehirae, 20 parts of rhizoma gastrodiae, 5 parts of honeysuckle branches, 10 parts of vitis amurensis, 3 parts of crushed notopterygium root, 4 parts of east Asian tree fern rhizome, 3 parts of drynaria rhizome and 5 parts of oyster shell into a container for later use;
(2) sealing and leaching: adding rice wine with the alcohol concentration of 50-60% Vol into a container according to the weight part ratio, wherein the ratio of the total amount of the fresh medicinal materials and the dry medicinal materials to the rice wine is as follows: 1: (2.0-2.8), completely soaking the medicinal materials in rice wine, further, sealing the container at the normal temperature of 20-30 ℃ for 2-3 months, finally forming upper-layer clear liquid and lower-layer medicine dregs deposited at the bottom of the container in the container, and taking out the mixed liquid of the medicine dregs and the leaching liquor in a pot for boiling when the clear liquid in the container, namely the leaching liquor, is in the color of strong coffee;
(3) the liquid medicine is prepared: and (3) heating in an open manner, boiling the open pot filled with the mixed solution by using a strong fire, then decocting for 2-2.5 hours by using a medium fire until the volume of the mixed solution is concentrated to 65-75% of the initial volume before heating, preferably 70%, then stopping heating, and filtering by using sterilized gauze to remove medicine residues to obtain the concentrated coffee clear liquid medicine. During filtering, the clear liquid medicine can be obtained by filtering for a plurality of times according to the filtering condition for later use.
Second, typical case
Case 1: gender women, age 44, onset 2012 early;
the joints of the ring finger, the middle finger and the two fingers are deformed and stiff and cannot move, the knee joints of the feet are seriously swollen and cannot be bent or straightened, the neck is stiff, the shoulders are painful, the wrist elbow joint is swollen, the movement is limited, the heartbeat is accelerated, the chest pain and the back pain are caused, the breath is short, the long-term dependence on the medicine is maintained, and the rheumatoid disease is diagnosed by a plurality of hospitals.
The treatment process with the liquid medicine of the invention is as follows: the medical cotton in a sheet shape with the thickness of 3-5 mm is soaked with the liquid medicine, the cotton soaked with the liquid medicine is preferably dry and wet without dripping, then the cotton is covered on an affected part, a preservative film is covered on the affected part, the cotton is heated to 40 ℃ by a thermotherapy device, the temperature of 40 ℃ is maintained, the heating time is kept for 60-90 min, and the morning and evening are treated for 2 times. Therefore, after 5-7 days, the joint of the affected part is not painful under the state of static and no violent movement; after 15 days, the affected joint starts to move actively, the heartbeat tends to be stable, and the digestive system in the endocrine system returns to be normal; after 50 days, the application treatment of the liquid medicine is stopped, the liquid medicine does not depend on the original medicine (before the treatment by using the liquid medicine of the invention) to be taken for maintenance, and reversible cure is achieved; after 4 months, the joints of all affected parts of the body are normal as before the disease occurs, and the body is not abnormal until now after repeated visits.
Case 2: sex men, age 50 years, time of onset 2009 and 10 months;
the fingers of both feet are bent, the hip joints are swollen and deformed, the fingers of both hands are stiff, the shoulders are painful, the spine is stiff and painful, the hands are weak to lift, the patients are diagnosed with rheumatoid disease through a plurality of hospitals, and the patients are maintained after taking the medicine for a long time.
The treatment process with the liquid medicine of the invention is as follows: the medical cotton in a sheet shape with the thickness of 3-5 mm is soaked with the liquid medicine, the cotton soaked with the liquid medicine is preferably dry and wet without dripping, then the cotton is covered on an affected part, a preservative film is covered on the affected part, the cotton is heated to 40 ℃ by a thermotherapy device, the temperature of 40 ℃ is maintained, the heating time is kept for 60-90 min, and the morning and evening are treated for 2 times. After 5-7 days, the joints are not painful under the condition of no violent movement, after 15-20 days, the joints start to move, original medicine taking is reduced, swelling is eliminated, after 40-50 days, all original medicine taking is stopped, application and treatment of the liquid medicine are stopped, and the state of an illness is recovered to more than six months; after 4 months, the body of the patient is recovered to be normal before the disease without sequela, and noninvasive and reversible healing is achieved. By revisit, the patients are healthy and normal.
The invention adopts a method of combining cold soaking and hot dipping when preparing the liquid medicine. Firstly, soaking the medicinal materials in rice wine in proportion by adopting a cold soaking method, wherein the rice wine comprises ethanol and water, according to the principle of 'similarity and intermiscibility', the ethanol in the rice wine can dissolve nonpolar and weak polar components in the medicinal materials, and the water can dissolve polar components in the medicinal materials. After cold soaking, the invention adopts a hot dipping method to heat and leach the mixed liquor of the medicine and the wine after cold soaking, so that the effective components in the medicinal materials are fully leached, and the medicine property of the medicinal materials is fully activated. Most of the alcohol volatilizes after heating, so that the concentration of the effective components of the traditional Chinese medicinal materials in the liquid medicine is increased. Can be transferred to the affected joint of the body after the treatment by heating the active ingredient thermotherapy device. The formula of the invention has scientific compatibility, and the components supplement each other. The liquid medicine prepared by the invention has the advantages of pertinence, rigidity relieving, atrophy resisting, nodulation relieving, tendon and vessel softening, ligament softening, inflammation diminishing, qi and blood circulation promoting, immunity improving, rheumatism resisting factor, no injection in the treatment process, direct external application, simplicity, safety and no side effect.
The invention provides an external medicine for treating rheumatoid disease, a formula and a preparation method thereof, the external medicine is used for treating rheumatoid arthritis, and the follow-up revisit of patients shows that the medicine has excellent curative effect, easy absorption, quick effect, obvious drug effect, difficult relapse and simple and convenient use, and provides a new medicine selection for clinic. Avoids various inconveniences brought by oral administration or operation, is easy to be accepted by patients and has good curative effect.
The above examples are not intended to limit the formulation and method of the present invention, and any suitable changes or modifications made by those skilled in the art should be considered as not departing from the scope of the present invention.
Claims (4)
1. The external medicine for treating rheumatoid diseases is characterized in that a formula comprises a fresh medicinal material and a dry medicinal material, wherein the fresh medicinal material and the dry medicinal material are correspondingly prepared from the following components in parts by weight:
fresh medicinal materials:
20-32 parts of vitex negundo;
18-20 parts of cinnamomum kanehirae leaves;
16-22 parts of Tuniuqi;
3-8 parts of honeysuckle branches;
8-15 parts of vitis amurensis;
picking and cleaning fresh medicinal materials including vitex negundo, cinnamomum kanehirae, radix achyranthis bidentatae, honeysuckle branches and vitis vinifera, and naturally airing the surface moisture of the fresh medicinal materials;
(II) dry medicinal materials:
2-5 parts of notopterygium root;
3-6 parts of rhizoma cibotii;
2-5 parts of rhizoma drynariae;
3-8 parts of oyster shells.
2. The method for producing an external preparation for treating rheumatoid disease according to claim 1, characterized by comprising the steps of:
(1) preparing medicinal materials: respectively crushing dry medicinal materials of notopterygium root, east Asian tree fern rhizome, drynaria rhizome and oyster shell into sawdust, and filling the components into a container according to the corresponding weight parts of the formula for later use;
(2) sealing and leaching: adding rice wine with the alcohol concentration of 50-60% Vol into a container according to the weight part ratio, wherein the ratio of the total amount of the fresh medicinal materials and the dry medicinal materials to the rice wine is as follows: 1: (2.0-2.8), completely soaking the medicinal materials in rice wine, further sealing the container at the normal temperature of 20-30 ℃ for 2-3 months, taking out the mixed liquid of the medicine residues and the leaching liquor into a pot when the clear liquid in the container is in the color of strong coffee, and waiting for boiling;
(3) the liquid medicine is prepared: and (3) heating in an open manner, boiling the open pot filled with the mixed solution by using a strong fire, then decocting for 2-2.5 hours by using a medium fire until the volume of the mixed solution is concentrated to 65-75% of the initial volume before heating, then stopping heating, and filtering by using sterilized gauze to remove medicine residues to obtain clear liquid medicine with the color of strong coffee for later use.
3. An external medicine for treating rheumatoid diseases, which is characterized in that: the formula comprises fresh medicinal materials and dry medicinal materials, wherein the fresh medicinal materials and the dry medicinal materials are correspondingly prepared from the following components in parts by weight:
fresh medicinal materials:
25 parts of vitex negundo;
25 parts of cinnamomum kanehirae leaves;
20 parts of Tuniuqi;
5 parts of honeysuckle branches;
10 parts of vitis amurensis;
(II) dry medicinal materials:
notopterygium root 3 parts;
4 parts of rhizoma cibotii;
3 parts of rhizoma drynariae;
5 parts of oyster shell.
4. A method of preparing an external medicament for the treatment of rheumatoid disease as claimed in claim 3, which comprises the steps of:
(1) preparing medicinal materials: respectively crushing dry medicinal materials of notopterygium root, east Asian tree fern rhizome, drynaria rhizome and oyster shell into sawdust, and filling the components into a container according to the corresponding weight parts of the formula for later use;
(2) sealing and leaching: adding rice wine with the alcohol concentration of 50-60% Vol into a container according to the weight part ratio, wherein the ratio of the total amount of the fresh medicinal materials and the dry medicinal materials to the rice wine is as follows: 1: (2.0-2.8), completely soaking the medicinal materials in rice wine, further sealing the container at the normal temperature of 20-30 ℃ for 2-3 months, taking out the mixed liquid of the medicine residues and the leaching liquor into a pot when the clear liquid in the container is in the color of strong coffee, and waiting for boiling;
(3) the liquid medicine is prepared: and (3) heating in an open manner, boiling the open pot filled with the mixed solution by using a strong fire, then decocting for 2-2.5 hours by using a medium fire until the volume of the mixed solution is concentrated to 65-75% of the initial volume before heating, then stopping heating, and filtering by using sterilized gauze to remove medicine residues to obtain clear liquid medicine with the color of strong coffee for later use.
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| CN100998656A (en) * | 2006-01-13 | 2007-07-18 | 闫长群 | Medicated wine for tonifying bone and removing obstruction in channels |
| CN105998273A (en) * | 2016-07-25 | 2016-10-12 | 商共朝 | External medicinal liquor for curing rheumatism |
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