CN115300569A - Traditional Chinese medicine composition for treating rheumatic bone pain and muscle injury and application thereof - Google Patents

Traditional Chinese medicine composition for treating rheumatic bone pain and muscle injury and application thereof Download PDF

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CN115300569A
CN115300569A CN202210886702.9A CN202210886702A CN115300569A CN 115300569 A CN115300569 A CN 115300569A CN 202210886702 A CN202210886702 A CN 202210886702A CN 115300569 A CN115300569 A CN 115300569A
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parts
root
traditional chinese
chinese medicine
muscle injury
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何军
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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    • A61K31/125Camphor; Nuclear substituted derivatives thereof
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    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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Abstract

The invention discloses a traditional Chinese medicine composition for treating rheumatic ostealgia and muscle injury, which comprises the following raw materials in parts by weight: 2 to 6 parts of borneol, 5 to 10 parts of camphor, 5 to 10 parts of myrrh, 2 to 10 parts of safflower, 6 to 10 parts of drynaria rhizome, 5 to 10 parts of pubescent angelica root, 5 to 10 parts of teasel root, 5 to 10 parts of medicinal cyathula root, 5 to 10 parts of dried rehmannia root, 5 to 10 parts of pinellia tuber, 5 to 10 parts of dragon's blood, 5 to 10 parts of angelica, 5 to 10 parts of szechuan lovage rhizome, 5 to 10 parts of manchurian wildginger, 5 to 10 parts of dahurian angelica root, 5 to 10 parts of raw arisaema tuber, 6 to 10 parts of vegetable oil, 2 to 10 parts of sea dragon, 2 to 10 parts of sea horse, 5 to 10 parts of paniculate swallowwort root, 5 to 10 parts of cassia twig, 5 to 10 parts of vietnamese sophora root, 5 to 10 parts of atractylodes rhizome, 5 to 10 parts of yellow lead, 2 to 10 parts of common monkshood mother root, 2 to 10 parts of amur corktree bark and 2 to 10 parts of amur corktree bark. The invention can effectively improve local blood circulation, has the effects of promoting blood circulation by removing blood stasis, clearing away heat and toxic materials, removing dampness and promoting granulation, is used for treating rheumatic ostealgia, has obvious curative effect on muscle injury, has low cost, does not generate scar hyperplasia after treatment, and has good popularization and application values.

Description

Traditional Chinese medicine composition for treating rheumatic bone pain and muscle injury and application thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating rheumatic bone pain and muscle injury and application thereof.
Background
Rheumatism pain, muscle injury, traumatic injury and the like are common clinical phenomena, wherein the rheumatism and rheumatoid diseases are pains caused by wind-cold accumulation in a body in long-term labor and work, joint pain, lumbago, foot pain, osteoarticular pain and the like are externally shown to seriously prevent the body health, and the muscle injury is mainly pain caused by skeletal muscle injury swelling and related soft tissue and connective tissue damage caused by various factors such as overworking, obstacle bump, traumatic injury and the like.
The main purpose of the medicine after the rheumatism bone pain and the muscle injury is to resist swelling and blood stasis caused by pain, improve the body immunity function through the blood stasis, and ensure the recovery of the motor functions of each system, each limb and the body of a patient. At present, the treatment of the rheumatic bone pain and the muscle injury mainly adopts modes of operation, oral administration or injection of pain-relieving and inflammation-diminishing medicines and the like, although the treatment can effectively treat diseases and promote wound healing, the defects of high price, great body injury caused by the operation, painful treatment process, scars left after healing and the like exist. At present, some Chinese herbal medicines are also used for adjuvant therapy clinically, but the effect is not ideal.
Disclosure of Invention
The technical problem to be solved by the invention is to provide a traditional Chinese medicine composition for treating rheumatic bone pain and muscle injury with good curative effect and application.
The technical problem solved by the invention is realized by adopting the following technical scheme:
a traditional Chinese medicine composition for treating rheumatic bone pain and muscle injury comprises the following raw materials in parts by weight: 2 to 6 parts of borneol, 5 to 10 parts of camphor, 5 to 10 parts of myrrh, 2 to 10 parts of safflower, 6 to 10 parts of drynaria rhizome, 5 to 10 parts of pubescent angelica root, 5 to 10 parts of teasel root, 5 to 10 parts of medicinal cyathula root, 5 to 10 parts of dried rehmannia root, 5 to 10 parts of pinellia tuber, 5 to 10 parts of dragon's blood, 5 to 10 parts of angelica, 5 to 10 parts of szechuan lovage rhizome, 5 to 10 parts of manchurian wildginger, 5 to 10 parts of dahurian angelica root, 5 to 10 parts of raw arisaema tuber, 6 to 10 parts of vegetable oil, 2 to 10 parts of sea dragon, 2 to 10 parts of sea horse, 5 to 10 parts of paniculate swallowwort root, 5 to 10 parts of cassia twig, 5 to 10 parts of vietnamese sophora root, 5 to 10 parts of largehead atractylodes rhizome, 5 to 10 parts of yellow kusnezoff monkshood root, 2 to 10 parts of common monkshood mother root, 2 to 10 parts of amur corktree bark and 2 to 10 parts of amur corktree bark.
Preferably, the traditional Chinese medicine composition consists of the following raw materials in parts by weight: 2 parts of borneol, 5 parts of camphor, 5 parts of myrrh, 2 parts of safflower, 6 parts of drynaria rhizome, 6 parts of pubescent angelica root, 6 parts of teasel root, 6 parts of medicinal cyathula root, 6 parts of dried rehmannia root, 6 parts of pinellia tuber, 5 parts of dragon's blood, 32663;, 5 parts of rhizome of Sichuan lovage, 5 parts of asarum, 5 parts of dahurian angelica root, 5 parts of raw arisaema root, 9 parts of vegetable oil, 2 parts of sea dragon, 2 parts of sea horse, 6 parts of paniculate swallowwort root, 6 parts of cassia twig, 5 parts of subprostrate sophora, 5 parts of atractylodes, 8 parts of yellow lead, 3 parts of common monkshood mother root, 3 parts of kusnezoff monkshood root and 2 parts of amur corktree bark.
Further, the radix aconiti is prepared radix aconiti kusnezoffii.
Further, the vegetable oil is medical tung oil.
The invention also relates to application of the traditional Chinese medicine composition in preparing a medicine for treating rheumatic bone pain and muscle loss.
Furthermore, the dosage form of the medicine is plaster.
Further, the preparation method of the plaster comprises the following steps: weighing the raw materials in proportion, crushing the raw materials except the vegetable oil to obtain traditional Chinese medicine powder, mixing the traditional Chinese medicine powder, the vegetable oil and a proper amount of water, decocting the mixture with small fire to obtain pasty ointment, and preparing the ointment into a sheet-shaped plaster.
The application method of the plaster comprises the following steps: cleaning the affected part with alcohol, heating until the plaster is slightly viscous, and applying on the affected part, wherein the plaster is applied within a small range slightly exceeding the affected part, and changing the plaster every 2 days until healing.
In the invention:
borneol: pungent, bitter and slightly cold; the functional indications are as follows: induce resuscitation and refresh mind, relieve swelling and alleviate pain.
Camphor: pungent and hot; the functional indications are as follows: dispel heat and alleviate pain, induce resuscitation and avoid filth.
Myrrh: bitter, pungent and mild, the main function is: promoting blood circulation to arrest pain, eliminating swelling and promoting granulation
Safflower: warm, pungent and functional indications: promoting blood circulation, dredging channels, removing blood stasis, and relieving pain.
Rhizoma drynariae: bitter taste, warm nature, pain relieving, and muscle and bone strengthening.
The pubescent angelica is pungent, bitter and slightly warm; the functional indications are as follows: dispelling pathogenic wind, removing dampness, dispelling cold, and relieving pain.
Teasel root: bitter, pungent, sweet and slightly damp; the functional indications are as follows: strengthen tendons and bones, regulate blood vessels, and stop metrorrhagia and metrostaxis.
Radix cyathulae: sweet and slightly bitter; the functional indications are as follows: to smooth the joints.
Dried rehmannia root, radix rehmanniae is sweet and cold; the functional indications are as follows: clear heat and cool blood, nourish yin and promote the production of body fluid.
Pinellia tuber seed: pungent and warm; the functional indications are as follows: resolve phlegm and dissipate nodulation, resolve swelling and dissipate nodulation.
Dragon's blood: sweet, salty and neutral; the functional indications are as follows: promoting blood circulation, removing blood stasis, relieving pain, stopping bleeding, promoting the generation of vital energy and healing wound.
32663 and alive: pungent, bitter and warm; the functional indications are as follows: relieve exterior syndrome, dispel cold, expel dampness and alleviate pain.
Ligusticum wallichii: pungent and warm; the functional indications are as follows: promote blood circulation and move qi, dispel wind and dredge collaterals to relieve pain.
Asarum: pungent and warm; the functional indications are as follows: dispel wind, release exterior syndrome, dispel cold and alleviate pain.
Radix angelicae: pungent and warm; the functional indications are as follows: dispel wind, alleviate pain, relieve swelling, expel pus, moisten skin and relieve itching.
Rhizoma arisaematis: pungent, bitter and warm; the functional indications are as follows: dry dampness and resolve phlegm, dispel the symptoms of spasmolysis, resolve swelling and dissipate nodulation.
Sea dragon: sweet, salty and warm; the functional indications are as follows: relieving swelling, dispersing pathogen accumulation, promoting blood circulation, removing blood stasis, relieving inflammation and pain
Sea horse: sweet, salty and warm; the functional indications are as follows: dissipating stagnation and relieving swelling, swelling of waist and legs, carbuncle, swelling, sore and furuncle.
Paniculate swallowwort root: pungent and warm; the functional indications are as follows: dispel wind, dredge collaterals, detoxify and relieve itching.
Cassia twig: pungent, sweet and slightly wet; the functional indications are as follows: induce sweating to expel pathogenic factors from the muscles, warm and dredge meridians, strengthen yang and transform qi.
Subprostrate sophora root: bitter and cold; the functional indications are as follows: clear heat and remove toxicity, relieve sore throat and relieve swelling.
Bishu: pungent, bitter and warm; the functional indications are as follows: dry dampness and strengthen spleen, dispel wind and remove dampness, improve eyesight.
Yellow lead: pungent, bitter and warm; the functional indications are as follows: detoxication, removing putrefaction, astringing dampness, healing wound, subduing phlegm and relieving convulsion
Radix aconiti: pungent, salty and warm; the functional indications are as follows: dispel wind and dampness, relieve pain by anesthesia, resolve swelling and remove putridity.
Kusnezoff monkshood root: pungent, bitter and hot; the functional indications are as follows: dispel wind and remove dampness, warm meridians and relieve pain, resolve swelling and remove putridity.
And (3) golden cypress: bitter and cold, main indications of functions: purging pathogenic fire and removing toxic substances; clear heat and dry dampness.
Medical tung oil: sweet, pungent and cold; the functional indications are as follows: to visit and spit wind-phlegm, it is externally used to treat scabies and tinea.
Has the beneficial effects that: the traditional Chinese medicine considers that the rheumatism pain, the muscle injury and the traumatic injury can cause qi stagnation and blood stasis, the stasis is not smooth, the stasis is smooth and the pain is caused, the qi stagnation is dampness accumulation, and the dampness accumulation is soft and the pain is caused. Clinical tests prove that after the Chinese herbal medicine and the ointment prepared from the Chinese herbal medicine are used for treating patients suffering from rheumatic pain, muscle injury and traumatic injury, the Chinese herbal medicine can effectively improve local blood circulation, does not generate the problem of scar hyperplasia after treatment, and has the advantages of low cost, remarkable curative effect, easy use process of patients and less damage to organisms.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described in the following combined with the specific embodiments.
Example 1
The traditional Chinese medicine composition for treating rheumatic bone pain and muscle injury comprises the following raw materials in parts by weight: 4 parts of borneol, 6 parts of camphor, 6 parts of myrrh, 3 parts of safflower, 7 parts of drynaria rhizome, 6 parts of pubescent angelica root, 6 parts of teasel root, 6 parts of medicinal cyathula root, 6 parts of dried rehmannia root, 6 parts of pinellia tuber, 6 parts of dragon's blood, 32663;, 7 parts of Huo, 6 parts of Szechuan lovage rhizome, 10 parts of manchurian wildginger, 6 parts of dahurian angelica root, 5 parts of raw arisaema tuber, 9 parts of medical tung oil, 3 parts of sea dragon, 3 parts of sea horse, 6 parts of paniculate swallowwort root, 6 parts of cassia twig, 10 parts of subprostrate sophora, 10 parts of atractylodes, 6 parts of yellow lead, 3 parts of common monkshood mother root, 3 parts of kusnezoff monkshood root and 5 parts of amur corktree bark.
The traditional Chinese medicine composition is prepared into plaster, and the preparation method of the plaster comprises the following steps: weighing the raw materials in proportion, crushing the raw materials except the vegetable oil to obtain traditional Chinese medicine powder, mixing the traditional Chinese medicine powder, the vegetable oil and a proper amount of water, decocting the mixture with small fire to obtain pasty ointment, and preparing the ointment into a sheet-shaped plaster.
The application method of the plaster comprises the following steps: cleaning the affected part with alcohol, heating until the plaster is slightly viscous, and applying on the affected part, wherein the plaster is applied within a small range slightly exceeding the affected part, and one plaster is replaced every 48-72 h until healing.
Example 2
The traditional Chinese medicine composition for treating rheumatic bone pain and muscle injury comprises the following raw materials in parts by weight: 6 parts of borneol, 6 parts of camphor, 7 parts of myrrh, 3 parts of safflower, 7 parts of drynaria rhizome, 6 parts of pubescent angelica root, 6 parts of teasel root, 6 parts of medicinal cyathula root, 8 parts of dried rehmannia root, 6 parts of pinellia tuber, 10 parts of dragon's blood, 32663;, 5 parts of rhizome of Sichuan lovage, 6 parts of szechuan lovage, 5 parts of asarum, 5 parts of dahurian angelica root, 5 parts of raw arisaema tuber, 8 parts of medical tung oil, 5 parts of sea dragon, 5 parts of sea horse, 6 parts of paniculate swallowwort root, 6 parts of cassia twig, 10 parts of subprostrate sophora, 5 parts of atractylodes, 7 parts of yellow lead, 4 parts of common monkshood mother root, 5 parts of kusnezoff monkshood root and 4 parts of amur corktree bark.
The traditional Chinese medicine composition is prepared into plaster, and the preparation method of the plaster comprises the following steps: weighing the raw materials in proportion, crushing the raw materials except the vegetable oil to obtain traditional Chinese medicine powder, mixing the traditional Chinese medicine powder, the vegetable oil and a proper amount of water, decocting the mixture with small fire to obtain pasty ointment, and preparing the ointment into a sheet-shaped plaster.
The application method of the plaster comprises the following steps: cleaning the affected part with alcohol, heating until the plaster is slightly viscous, and changing one plaster at 48-72 hr until the plaster is healed.
Example 3
The traditional Chinese medicine composition for treating rheumatic bone pain and muscle injury in the embodiment is prepared from the following raw materials in parts by weight: 2 parts of borneol, 5 parts of camphor, 5 parts of myrrh, 2 parts of safflower, 6 parts of drynaria rhizome, 6 parts of pubescent angelica root, 6 parts of teasel root, 6 parts of medicinal cyathula root, 6 parts of dried rehmannia root, 6 parts of pinellia tuber, 5 parts of dragon's blood, 32663;, 5 parts of rhizome of Sichuan lovage, 5 parts of asarum, 5 parts of dahurian angelica root, 5 parts of raw arisaema root, 9 parts of vegetable oil, 2 parts of sea dragon, 2 parts of sea horse, 6 parts of paniculate swallowwort root, 6 parts of cassia twig, 5 parts of subprostrate sophora, 5 parts of atractylodes, 8 parts of yellow lead, 3 parts of common monkshood mother root, 3 parts of kusnezoff monkshood root and 2 parts of amur corktree bark.
The traditional Chinese medicine composition is prepared into plaster, and the preparation method of the plaster comprises the following steps: weighing the raw materials in proportion, crushing the raw materials except the vegetable oil to obtain traditional Chinese medicine powder, mixing the traditional Chinese medicine powder, the vegetable oil and a proper amount of water, decocting the mixture with small fire to obtain pasty ointment, and preparing the ointment into a sheet-shaped plaster.
The application method of the plaster comprises the following steps: cleaning the affected part with alcohol, heating until the plaster is slightly viscous, and changing one plaster at 48-72 hr until the plaster is healed.
Comparative example 1
The traditional Chinese medicine composition for treating rheumatic bone pain and muscle injury comprises the following raw materials in parts by weight: 2 parts of borneol, 2 parts of camphor, 2 parts of myrrh, 2 parts of safflower, 2 parts of drynaria rhizome, 2 parts of pubescent angelica root, 2 parts of teasel root, 2 parts of medicinal cyathula root, 2 parts of dried rehmannia root, 2 parts of pinellia tuber, 2 parts of dragon's blood, 32663;, 2 parts of rhizome of Sichuan lovage, 2 parts of asarum, 2 parts of dahurian angelica root, 2 parts of arisaema tuber, 2 parts of vegetable oil, 2 parts of sea dragon, 2 parts of sea horse, 2 parts of paniculate swallowwort root, 2 parts of cassia twig, 2 parts of subprostrate sophora, 2 parts of atractylodes, 2 parts of yellow lead, 10 parts of common monkshood mother root, 10 parts of wild aconite root and 2 parts of amur corktree bark.
The traditional Chinese medicine composition is prepared into plaster, and the preparation method of the plaster comprises the following steps: weighing the raw materials in proportion, crushing the raw materials except the vegetable oil to obtain traditional Chinese medicine powder, mixing the traditional Chinese medicine powder, the vegetable oil and a proper amount of water, decocting the mixture with small fire to obtain pasty ointment, and preparing the ointment into a sheet-shaped plaster.
When the embodiment is applied, the medicine is retained on the surface of the skin, the residue is more, the subsequent cleaning is difficult, the practical application is limited, the curative effect is certain, and the effect is not obvious.
In order to verify the experimental effect of the invention, more than 400 cases of patients with symptoms of rheumatic pain, muscle injury and traumatic injury in clinic are treated and observed in succession, wherein 300 patients in adults comprise light and heavy patients, and 150 patients in children comprise light and heavy patients. After the plaster is used, the effective rate reaches up to 100 percent, the problem of scar hyperplasia does not occur after healing, and the curative effect is obvious. Wherein the formulation of example 3 is most efficacious.
The treatment results are comprehensively judged according to the description of the patient, visual observation and CT inspection results.
Typical cases and efficacy:
case 1: he Mou, male, age 52. In 04 months in 2020, the patient who is a diabetic falls on the right foot by driving a motorcycle, has a large open wound surface, does not hurt bones but has a deep wound surface and can see white bones, the pain surface of the patient is cleaned, the plaster of the embodiment 3 of the invention is applied, the dressing is changed every 72 hours, and the patient is cured in 9 days. After healing, no scar is generated.
Case 2: nie Mou, a man, a person in Qingquan Zhengda village in Guidong county, hunan province, nie is a pig killer, four pig killers slip on a heavy site when the pig is grabbed at four night of 5 months and 4 days in 2022 years, the waist is sprained due to excessive force in pulling, no trauma is caused, the pain is severe, and the waist can not rise up directly, so that the pig can be healed after being pasted with the plaster of the embodiment 3 of the invention.
Case 3: he Mou, male, 57 year old. When the house is decorated at home and the staircase is painted, the bridge plate is broken and falls onto the edge of the stair step in the Qingquan Zhenshan county in Guidong county, hunan province in 2022 months. According to the diagnosis of DR2 shooting results of county hospitals, the L1 vertebral body deforms, changes in a wedge shape, compresses by about 2/3, is accompanied by hyperosteogeny, changes the medicine every 48 hours, is continuously applied with the plaster of the embodiment 3 of the invention, and is basically cured after being continuously applied for 2 months. The method can be used for continuously constructing the foundation construction at present.
Case 4: zhou Mou, a woman, a person in town of Tuchuan county, jiangxi province, has pain in the rheumatism plaster of feet and knees for more than ten years, and has no effect when going to medical treatment everywhere, after the plaster disclosed by the embodiment 1 of the invention is applied for 6 months and 7 days in 2022 years, the effect is obvious, the plaster is continuously applied for one time in 6 months and 15 days, and the result is completely recovered after return visit in 7 months and 15 days.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (7)

1. A traditional Chinese medicine composition for treating rheumatic bone pain and muscle injury is characterized by comprising the following raw materials in parts by weight: 2 to 6 parts of borneol, 5 to 10 parts of camphor, 5 to 10 parts of myrrh, 2 to 10 parts of safflower, 6 to 10 parts of drynaria rhizome, 5 to 10 parts of pubescent angelica root, 5 to 10 parts of teasel root, 5 to 10 parts of medicinal cyathula root, 5 to 10 parts of dried rehmannia root, 5 to 10 parts of pinellia tuber, 5 to 10 parts of dragon's blood, 5 to 10 parts of angelica, 5 to 10 parts of szechuan lovage rhizome, 5 to 10 parts of manchurian wildginger, 5 to 10 parts of dahurian angelica root, 5 to 10 parts of raw arisaema tuber, 6 to 10 parts of vegetable oil, 2 to 10 parts of sea dragon, 2 to 10 parts of sea horse, 5 to 10 parts of paniculate swallowwort root, 5 to 10 parts of cassia twig, 5 to 10 parts of vietnamese sophora root, 5 to 10 parts of largehead atractylodes rhizome, 5 to 10 parts of yellow kusnezoff monkshood root, 2 to 10 parts of common monkshood mother root, 2 to 10 parts of amur corktree bark and 2 to 10 parts of amur corktree bark.
2. The traditional Chinese medicine composition for treating rheumatic bone pain and muscle injury according to claim 1, which is prepared from the following raw materials in parts by weight: 2 parts of borneol, 5 parts of camphor, 5 parts of myrrh, 2 parts of safflower, 6 parts of drynaria rhizome, 6 parts of pubescent angelica root, 6 parts of teasel root, 6 parts of medicinal cyathula root, 6 parts of dried rehmannia root, 6 parts of pinellia tuber, 5 parts of dragon's blood, 32663;, 5 parts of rhizome of Sichuan lovage, 5 parts of asarum, 5 parts of dahurian angelica root, 5 parts of raw arisaema root, 9 parts of vegetable oil, 2 parts of sea dragon, 2 parts of sea horse, 6 parts of paniculate swallowwort root, 6 parts of cassia twig, 5 parts of subprostrate sophora, 5 parts of atractylodes, 8 parts of yellow lead, 3 parts of common monkshood mother root, 3 parts of kusnezoff monkshood root and 2 parts of amur corktree bark.
3. The Chinese medicinal composition for treating rheumatic bone pain and muscle injury according to claim 1, wherein the radix aconiti is prepared radix aconiti chuanxiong.
4. The Chinese medicinal composition for treating rheumatic bone pain and muscle injury according to claim 1, wherein the vegetable oil is medical tung oil.
5. The use of the Chinese medicinal composition of claim 1 in the preparation of a medicament for the treatment of rheumatic bone pain and muscle loss.
6. The use according to claim 5, wherein the medicament is in the form of a plaster.
7. The use according to claim 6, wherein the plaster is prepared by a process comprising: weighing the raw materials in proportion, pulverizing the raw materials except vegetable oil to obtain traditional Chinese medicine powder, mixing the traditional Chinese medicine powder, the vegetable oil and a proper amount of water, decocting with slow fire to obtain paste, and making the paste into sheet plaster.
CN202210886702.9A 2022-07-26 2022-07-26 Traditional Chinese medicine composition for treating rheumatic bone pain and muscle injury and application thereof Pending CN115300569A (en)

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