CN111568979A - Health-care compound essential oil for improving immunity - Google Patents

Health-care compound essential oil for improving immunity Download PDF

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CN111568979A
CN111568979A CN202010529467.0A CN202010529467A CN111568979A CN 111568979 A CN111568979 A CN 111568979A CN 202010529467 A CN202010529467 A CN 202010529467A CN 111568979 A CN111568979 A CN 111568979A
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parts
essential oil
compound essential
oil
rhizoma atractylodis
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王健英
张磊
赵咏芳
洪燕龙
胡晓娟
张宝军
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Shanghai University of Traditional Chinese Medicine
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Shanghai University of Traditional Chinese Medicine
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Abstract

The invention discloses a health compound essential oil for improving immunity, which comprises the following components in parts by mass: 8-12 parts of wormwood, 4-9 parts of rhizoma atractylodis, 2-4 parts of dried orange peel, 3-5 parts of mangnolia officinalis, 0.5-1.5 parts of rhizoma acori graminei, 0.5-1.5 parts of flos caryophyllata, 0.5-1.5 parts of cinnamon bark, 0.5-1.5 parts of liquorice, 0.5-1.5 parts of rhizoma atractylodis macrocephalae, 0.4-0.6 part of agilawood and 90-95 parts of base oil. After various traditional Chinese medicines are reasonably mixed, the solution has aromatic smell, can generate positive influence on a human body, can improve the immunity of the human body, is natural, mellow and not greasy after being smelled for a long time, can add 2-5 drops of +200ml of clean water according to the individual smell, and can expand fragrance by a fragrance expanding machine; and 10 drops of compound essential oil and 10ml of base oil can be used, and a proper amount of hands are taken to rub the base oil and then massage the base oil on the skin or acupuncture points, so that the application range is wide.

Description

Health-care compound essential oil for improving immunity
Technical Field
The invention relates to essential oil, in particular to guard compound essential oil for improving immunity.
Background
Cang Zhu is pungent and bitter in flavor and warm in nature. It enters spleen, stomach and liver meridians. Has the effects of eliminating dampness, strengthening spleen, dispelling pathogenic wind, dispelling cold, and improving eyesight. Can inhibit growth of fungi, bacteria and viruses, and can be used for sterilizing air.
Rhizoma Atractylodis-rhizome, as a medicine for activating spleen, is bitter, warm, pungent and strong in property, and has the effects of drying dampness, resolving turbidity and relieving pain.
Tangerine peel, bitter and pungent in flavor, warm in nature, regulating qi and strengthening spleen, drying dampness and resolving phlegm, is used for abdominal fullness and distention, poor appetite, vomiting and diarrhea, cough and profuse sputum.
Magnolia officinalis, cortex Magnolia officinalis, is pungent in flavor and warm in nature, and has effects of activating qi-flowing, eliminating dampness, warming spleen and stomach, relieving pain, and lowering adverse qi and relieving asthma. The Magnolia officinalis decoction has strong antibacterial effect on Staphylococcus, Streptococcus, Bacillus dysenteriae, Pasteurella and Vibrio cholerae; but also has a certain relieving effect on striated muscle stiffness.
The rhizoma acori graminei-rhizoma acori graminei volatile oil (beta-asarone) has the effect of dilating the coronary vessels of the guinea pig at a certain concentration. It is often used for treating coronary heart disease and pulmonary heart disease, and is also related to its mechanism of increasing coronary blood flow, tranquilizing, improving digestive function, relieving asthma and cough.
Flos Caryophylli has antibacterial, antifungal, anthelmintic, stomach invigorating, and analgesic effects.
Cinnamon bark, pungent in flavor, warm in nature. Has the effects of warming spleen and stomach, dispelling cold, relieving exterior syndrome and inducing perspiration. Can be used for treating headache, aversion to cold, stomach cold, chest distress, etc. caused by affection of exogenous wind-cold. Can inhibit bacteria strongly.
Licorice root, radix Glycyrrhizae is commonly used for weakness of spleen and stomach, lassitude, hypodynamia, palpitation, shortness of breath, cough, profuse sputum, spasm and pain of abdomen and limbs, carbuncle, swelling, sore and toxicity, and for alleviating toxicity and intensity of drugs.
Bai Zhu-invigorating spleen, replenishing qi, drying dampness to induce diuresis, checking sweating, and preventing miscarriage. They belong to the category of qi tonics under deficiency-tonifying herbs.
Chenxiang has the actions of moving qi and alleviating pain, warming middle energizer and arresting vomiting, absorbing qi and relieving asthma. It is commonly used for chest and abdomen distention, stuffy pain, stomach cold, vomiting, hiccup, deficiency of the kidney, dyspnea with rapid and urgent respiration.
Disclosure of Invention
In order to solve the problems, the invention discloses a health compound essential oil for improving immunity.
The technical scheme of the invention is as follows: a guard compound essential oil for improving immunity comprises the following components by mass: 8-12 parts of wormwood, 4-9 parts of rhizoma atractylodis, 2-4 parts of dried orange peel, 3-5 parts of mangnolia officinalis, 0.5-1.5 parts of rhizoma acori graminei, 0.5-1.5 parts of flos caryophyllata, 0.5-1.5 parts of cinnamon bark, 0.5-1.5 parts of liquorice, 0.5-1.5 parts of rhizoma atractylodis macrocephalae, 0.4-0.6 part of agilawood and 90-95 parts of base oil.
Further, the compound essential oil for defending comprises the following components in mass: 10 parts of wormwood, 5 parts of rhizoma atractylodis, 3 parts of dried orange peel, 2 parts of mangnolia officinalis, 1 part of rhizoma acori graminei, 1 part of flos caryophyllata, 1 part of cinnamon bark, 1 part of liquorice, 1 part of rhizoma atractylodis macrocephalae, 0.5 part of agilawood and 90 parts of base oil.
Further, the compound essential oil for defending comprises the following components in mass: 11 parts of wormwood, 4 parts of rhizoma atractylodis, 4 parts of dried orange peel, 3 parts of mangnolia officinalis, 0.8 part of rhizoma acori graminei, 1.2 parts of flos caryophyllata, 1.1 parts of cinnamon bark, 1.2 parts of liquorice, 0.7 part of rhizoma atractylodis macrocephalae, 0.5 part of agilawood and 92 parts of base oil.
Further, the compound essential oil for defending comprises the following components in mass: 12 parts of wormwood, 8 parts of rhizoma atractylodis, 1 part of dried orange peel, 4 parts of mangnolia officinalis, 1 part of rhizoma acori graminei, 1.2 parts of flos caryophyllata, 1 part of cinnamon bark, 0.9 part of liquorice, 1 part of rhizoma atractylodis macrocephalae, 0.6 part of agilawood and 94 parts of base oil.
Further, the preparation method of the health compound essential oil comprises the following steps:
the method comprises the following steps: extracting rhizoma Atractylodis, pericarpium Citri Tangerinae, cortex Magnolia officinalis, rhizoma Acori Graminei, and Atractylodis rhizoma by supercritical carbon dioxide extraction to obtain volatile oil;
step two: extracting volatile oil from flos Caryophylli, cortex Cinnamomi, and Glycyrrhrizae radix by steam distillation;
step three: steam distilling to obtain volatile oil, and collecting steam condensate of folium Artemisiae Argyi to obtain folium Artemisiae Argyi water extractive solution;
step four: adding the above extracts into base oil according to components, mixing and stirring to obtain essential oil.
Further, the carbon oxide supercritical extraction method in the first step comprises the following extraction conditions: the temperature is 40-50 ℃ and the pressure is 6-30 MPa.
Further, the steam distillation method in the second step comprises the following operation methods: adding flos Caryophylli, cortex Cinnamomi, Glycyrrhrizae radix and distilled water into volatile oil extractor, and extracting by steam distillation for 4-6 hr to obtain volatile oil and residue.
Further, the steam distillation method in the third step comprises the following operation method: adding folium Artemisiae Argyi and distilled water into volatile oil extractor, and extracting by steam distillation for 4-6 hr to obtain volatile oil and residue.
Advantageous effects
After various traditional Chinese medicines are reasonably mixed, the solution has aromatic smell, can generate positive influence on a human body, can improve the immunity of the human body, is natural, mellow and not greasy after being smelled for a long time, can add 2-5 drops of +200ml of clean water according to the individual smell, and can expand fragrance by a fragrance expanding machine; and 10 drops of compound essential oil and 10ml of base oil can be used, and a proper amount of hands are taken to rub the base oil and then massage the base oil on the skin or acupuncture points, so that the application range is wide.
Detailed Description
The invention provides a health compound essential oil for improving immunity.
A guard compound essential oil for improving immunity comprises the following components by mass: 8-12 parts of wormwood, 4-9 parts of rhizoma atractylodis, 2-4 parts of dried orange peel, 3-5 parts of mangnolia officinalis, 0.5-1.5 parts of rhizoma acori graminei, 0.5-1.5 parts of flos caryophyllata, 0.5-1.5 parts of cinnamon bark, 0.5-1.5 parts of liquorice, 0.5-1.5 parts of rhizoma atractylodis macrocephalae, 0.4-0.6 part of agilawood and 90-95 parts of base oil.
The preparation method of the defending compound essential oil comprises the following steps:
the method comprises the following steps: extracting rhizoma Atractylodis, pericarpium Citri Tangerinae, cortex Magnolia officinalis, rhizoma Acori Graminei, and Atractylodis rhizoma by supercritical carbon dioxide extraction to obtain volatile oil;
step two: extracting volatile oil from flos Caryophylli, cortex Cinnamomi, and Glycyrrhrizae radix by steam distillation;
step three: steam distilling to obtain volatile oil, and collecting steam condensate of folium Artemisiae Argyi to obtain folium Artemisiae Argyi water extractive solution;
step four: adding the above extracts into base oil according to components, mixing and stirring to obtain essential oil.
The carbon oxide supercritical extraction method in the first step comprises the following extraction conditions: the temperature is 40-50 ℃, and the pressure is 6-30 MPa; the steam distillation method in the second step comprises the following operation methods: adding flos Caryophylli, cortex Cinnamomi, Glycyrrhrizae radix and distilled water into volatile oil extractor, and extracting by steam distillation for 4-6 hr to obtain volatile oil and residue; the steam distillation method in the third step comprises the following operation methods: adding folium Artemisiae Argyi and distilled water into volatile oil extractor, and extracting by steam distillation for 4-6 hr to obtain volatile oil and residue.
Example 1: fragrance sleep-aid effect test
Expanding fragrance and smelling: adding 10-20 drops of clean water and 100ml of clean water according to the smell of an individual, and expanding the fragrance by using a fragrance expanding machine. 5 groups are respectively set, 6 persons in each group are evaluated at different concentrations, and the results are as follows:
Figure BDA0002534860410000051
through investigation, experimenters generally react, after the compound essential oil is used, the sleep quality is improved, the mood is relieved, the fragrance is pleasant, the mood becomes joyful, and the air can be purified and regulated.
Example 2: test for absorption Effect
Gentle stroking: 1-3ml of compound essential oil and 10ml of base oil (jojoba oil), and kneading with hands, and massaging skin or acupuncture points. 5 groups are respectively set, 6 persons in each group are evaluated at different concentrations, and the results are as follows:
Figure BDA0002534860410000052
experimental data show that the compound essential oil has good absorption effect after use, and the skin is smooth and fragrant, and has moderate viscosity.
Example 3: 3% concentration compound oil, 28 days bacteriostasis challenge experiment method: the following bacteria and molds were added to the samples, respectively: 2x106cfu/ml Staphylococcus aureus Staphyloccocusaueus ATCC6538, 2x106cfu/ml Pseudomonas aeruginosa ATCC9027, 1x106cfu/ml E.coli Escherichia coli ATCC8739, 3X105cfu/ml Candida albicans CandidaalbicasATCC 10231, 4x105cfu/ml Aspergillus niger ATCC16404 (to simulate the worst production environment), and the number of colonies was measured after 7 days, 14 days, and 28 days at 37 ℃ in the incubator, respectively.
The experimental results are as follows:
Figure BDA0002534860410000061
the detection shows that the compound essential oil has no obvious character difference after the incubator and before the test, and all physical and chemical indexes and sanitary indexes of the compound essential oil accord with corresponding national standards.
Example 4: the experimental method for the influence of the compound oil on the immune function of the mouse comprises the following steps: a male mouse of clean grade is taken as a research object, the stomach is continuously drenched with compound oil of different doses for two weeks, and changes of NO and NOS in serum, spleen IL2 and IL6 are measured and analyzed.
The experimental results are as follows: serum NO levels and spleen IL2, IL6(n ═ 8) in mice of different treatment groups
Figure BDA0002534860410000062
There was a change in the levels of IL2 and IL6 in serum NO and spleen in each group compared with the blank group, with the levels in the high concentration group being significantly increased (*P is less than 0.01). The compound oil can be used as a bioactive substance to regulate the secretion of body cell factors and improve the body immunoregulation function.
Example 5: test of moisturizing Effect
The toner prepared by the embodiment of the invention is randomly selected from 100 volunteers for trial, and the compound essential oil is randomly used on one cheek of the left cheek or the right cheek of each volunteer and is used as an experimental group; one cheek of the volunteer, which was not used with the compound essential oil of the present invention, was used as a control group. The trial time is one month, and during the trial period, the skin cleaning cosmetics can be normally used, and other skin care cosmetics are not used so as not to influence the test result.
The score after use was 0-10, 0 parts was poor and 10 parts was very good, as shown in the statistical table below:
fragrance Absorbency of skin Moisture retention of skin Elasticity of skin
Control group 2.5 6.2 4.3 6.8
Experimental group 9.8 9.6 9.7 9.4
Through investigation, compared with a control group, the skin of the volunteer in the experimental group is obviously more moist and elastic, and the skin absorptivity is better. Meanwhile, the volunteers in the experimental group generally reflect that the compound essential oil disclosed by the invention is pleasant in fragrance and excellent in sensory experience.
Although the present invention has been described with reference to a preferred embodiment, it should be understood that various changes, substitutions and alterations can be made herein without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (8)

1. A defending compound essential oil for improving immunity is characterized in that: the composition comprises the following components in parts by mass: 8-12 parts of wormwood, 4-9 parts of rhizoma atractylodis, 2-4 parts of dried orange peel, 3-5 parts of mangnolia officinalis, 0.5-1.5 parts of rhizoma acori graminei, 0.5-1.5 parts of flos caryophyllata, 0.5-1.5 parts of cinnamon bark, 0.5-1.5 parts of liquorice, 0.5-1.5 parts of rhizoma atractylodis macrocephalae, 0.4-0.6 part of agilawood and 90-95 parts of base oil.
2. The compound essential oil for improving immunity according to claim 1, which is characterized in that: the compound essential oil for protection comprises the following components in parts by mass: 10 parts of wormwood, 5 parts of rhizoma atractylodis, 3 parts of dried orange peel, 2 parts of mangnolia officinalis, 1 part of rhizoma acori graminei, 1 part of flos caryophyllata, 1 part of cinnamon bark, 1 part of liquorice, 1 part of rhizoma atractylodis macrocephalae, 0.5 part of agilawood and 90 parts of base oil.
3. The compound essential oil for improving immunity according to claim 1, which is characterized in that: the compound essential oil for protection comprises the following components in parts by mass: 11 parts of wormwood, 4 parts of rhizoma atractylodis, 4 parts of dried orange peel, 3 parts of mangnolia officinalis, 0.8 part of rhizoma acori graminei, 1.2 parts of flos caryophyllata, 1.1 parts of cinnamon bark, 1.2 parts of liquorice, 0.7 part of rhizoma atractylodis macrocephalae, 0.5 part of agilawood and 92 parts of base oil.
4. The compound essential oil for improving immunity according to claim 1, which is characterized in that: the compound essential oil for protection comprises the following components in parts by mass: 12 parts of wormwood, 8 parts of rhizoma atractylodis, 1 part of dried orange peel, 4 parts of mangnolia officinalis, 1 part of rhizoma acori graminei, 1.2 parts of flos caryophyllata, 1 part of cinnamon bark, 0.9 part of liquorice, 1 part of rhizoma atractylodis macrocephalae, 0.6 part of agilawood and 94 parts of base oil.
5. The compound essential oil for improving immunity according to claim 1, which is characterized in that: the preparation method of the defending compound essential oil comprises the following steps:
the method comprises the following steps: extracting rhizoma Atractylodis, pericarpium Citri Tangerinae, cortex Magnolia officinalis, rhizoma Acori Graminei, and Atractylodis rhizoma by supercritical carbon dioxide extraction to obtain volatile oil;
step two: extracting volatile oil from flos Caryophylli, cortex Cinnamomi, and Glycyrrhrizae radix by steam distillation;
step three: steam distilling to obtain volatile oil, and collecting steam condensate of folium Artemisiae Argyi to obtain folium Artemisiae Argyi water extractive solution;
step four: adding the above extracts into base oil according to components, mixing and stirring to obtain essential oil.
6. The compound essential oil for improving immunity according to claim 1, which is characterized in that: the carbon oxide supercritical extraction method in the first step comprises the following extraction conditions: the temperature is 40-50 ℃ and the pressure is 6-30 MPa.
7. The compound essential oil for improving immunity according to claim 1, which is characterized in that: the steam distillation method in the second step comprises the following operation methods: adding flos Caryophylli, cortex Cinnamomi, Glycyrrhrizae radix and distilled water into volatile oil extractor, and extracting by steam distillation for 4-6 hr to obtain volatile oil and residue.
8. The compound essential oil for improving immunity according to claim 1, which is characterized in that: the steam distillation method in the third step comprises the following operation methods: adding folium Artemisiae Argyi and distilled water into volatile oil extractor, and extracting by steam distillation for 4-6 hr to obtain volatile oil and residue.
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CN115414283A (en) * 2022-09-26 2022-12-02 广东新会宝皮宝陈皮文化有限公司 Pericarpium citri reticulatae essential oil massage oil and preparation method and application thereof

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111568966A (en) * 2020-06-11 2020-08-25 上海中医药大学 Antibacterial liquid medicine capable of improving immunity of organism
CN115212258A (en) * 2021-06-04 2022-10-21 广州汽车集团股份有限公司 Vehicle-mounted fragrance and preparation method thereof
CN115414283A (en) * 2022-09-26 2022-12-02 广东新会宝皮宝陈皮文化有限公司 Pericarpium citri reticulatae essential oil massage oil and preparation method and application thereof
CN115414283B (en) * 2022-09-26 2023-11-28 广东新会宝皮宝陈皮文化有限公司 Pericarpium citri reticulatae essential oil massage oil and preparation method and application thereof

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