CN111544296B - Light energy storage bag for blood products - Google Patents

Light energy storage bag for blood products Download PDF

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Publication number
CN111544296B
CN111544296B CN202010562430.8A CN202010562430A CN111544296B CN 111544296 B CN111544296 B CN 111544296B CN 202010562430 A CN202010562430 A CN 202010562430A CN 111544296 B CN111544296 B CN 111544296B
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Prior art keywords
bag body
light
blood
inner bag
blood product
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CN202010562430.8A
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CN111544296A (en
Inventor
王倩
刘伟
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Sichuan Provincial Peoples Hospital
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Sichuan Provincial Peoples Hospital
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Priority to CN202010562430.8A priority Critical patent/CN111544296B/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10Bag-type containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02Blood transfusion apparatus
    • A61M1/0272Apparatus for treatment of blood or blood constituents prior to or for conservation, e.g. freezing, drying or centrifuging
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves

Abstract

The invention provides a blood product light energy storage bag, which relates to the technical field of medical equipment and comprises an inner bag body and an outer bag body. Wherein the outer bag body is wrapped on the periphery of the inner bag body. The inner space of the inner bag body is used for containing the blood products to be preserved. An interlayer is also formed between the outer bag body and the inner bag body, so that a certain setting space is provided for the luminous component. The light emitting component is arranged in the interlayer and can emit weak light to the blood contained in the inner bag body in the electrified state, and even the weak light irradiates on the blood product. Therefore, the biological stimulation effect of weak light is utilized to generate a certain activation effect on the blood product, so that the blood can keep a certain activity, namely, the activity of blood components can be maintained for a long time after the blood product is separated from a specific preservation environment, thereby improving the preservation time of the blood product after the blood product is separated from the body, facilitating the taking of subsequent clinical medical treatment, further improving the yield in the temporary preservation and transportation processes and improving the treatment effect.

Description

Light energy storage bag for blood products
Technical Field
The invention relates to the technical field of medical equipment, in particular to a blood product light energy storage bag.
Background
With the development of economy, intensive research into basic medicine has been conducted, and medical auxiliary equipment has become an indispensable role in medical procedures. In clinical medicine in particular, many operations or treatments require transfusion, and the manner of transfusion is classified into whole blood transfusion or component transfusion depending on the missing blood component of the patient. Whether whole blood transfusion or component transfusion, more medical auxiliary equipment is needed, for example, a needle tube is needed in the blood sampling stage; in the preservation stage, a preservation bag and the like are needed; in the blood transfusion stage, an intravenous injection and the like are required. Because the timing of donor delivery and the timing of patient demand often are difficult to match in real time, the collected blood product needs to be preserved for a period of time to cope with the clinical demands that may occur at any time. However, with the lengthening of the preservation time, the blood cells in the blood product are gradually inactivated and die, so that the clinical treatment effect is difficult to be expected. In order to improve the effect of surgery or therapy, it is necessary to improve the quality of blood products as much as possible during preservation, and therefore, how to preserve blood products has become a focus of medical attention.
The existing blood products are usually placed in transparent plastic bags and stored in a freezer at a low temperature to reduce the metabolism level of blood cells, even in transportation, the blood products are required to be placed in a specific preservation environment protected from light at a low temperature, otherwise, once the blood products are separated from the specific preservation environment, the blood products are extremely easy to deteriorate due to massive inactivation and death of the blood cells, so that the preservation time of the blood products is short, and the use is inconvenient.
Disclosure of Invention
The invention aims to overcome the defects in the prior art, and provides a blood product light energy storage bag which can improve the activity of components in the blood product or obtain certain quantity, property and state change by means of weak light irradiation of the blood product, so that the storage time of the blood product in storage and use is prolonged, and even the quantity, property and function of the blood component in storage can be changed and improved according to clinical expectations and demands.
In order to achieve the above purpose, the technical scheme adopted by the embodiment of the invention is as follows:
in one aspect of an embodiment of the present invention, there is provided a blood product light energy storage bag comprising: an inner bag and an outer bag wrapped with the inner bag; the inner bag body is used for accommodating blood products; an interlayer is formed between the outer bag body and the inner bag body, a light-emitting component is arranged in the interlayer, and the light-emitting component is used for emitting weak light towards the inner bag body.
Optionally, the blood product light energy storage bag further comprises a first connecting piece, one end of the first connecting piece is connected with the outer surface of the inner bag body, and the other end of the first connecting piece is connected with the inner surface of the outer bag body.
Optionally, the light emitting component is a light strip, and the light strip is arranged around the periphery of the inner bag body.
Optionally, the light strip includes a first light strip and a second light strip, the first light strip is wound around the outer periphery of the inner bag body along a first direction, the second light strip is wound around the outer periphery of the inner bag body along a second direction, and the first direction and the second direction are intersected.
Optionally, the luminous component comprises a plurality of luminous pieces arranged on the inner surface of the outer bag body, and the luminous pieces are uniformly distributed along the inner surface of the outer bag body.
Optionally, an insulation layer is also arranged on the outer bag body.
Optionally, the inner bag body is a transparent bag body, and the outer bag body is a shading bag body.
Optionally, an observation window is further arranged on the outer bag body close to the output end.
Optionally, the blood product light energy storage bag further comprises a storage battery, the storage battery is arranged in the interlayer, and the storage battery is electrically connected with the light emitting component.
Optionally, a communicating pipe is arranged on the inner bag body, the communicating pipe passes through the outer bag body to be communicated with the outside, and a sealer is arranged at a pipe orifice of the communicating pipe.
The beneficial effects of the invention include:
the invention provides a blood product light energy storage bag, which comprises an inner bag body and an outer bag body. Wherein, the outer bag body is sleeved on the periphery of the inner bag body. The inner space of the inner bag body is used for containing the blood products to be preserved. An interlayer is also formed between the outer bag body and the inner bag body, therebyAnd a certain setting space is provided for the luminous component. The luminous component is arranged in the interlayer and can emit weak light to the blood product contained in the inner bag body in the electrified state, the weak light is irradiation light which does not cause irreversible damage when directly irradiating the surface of the organism, the wavelength can be 280-10000nm, especially 380-2000nm, and the power output to the irradiated part is 0.01-90mW/cm 2 In between, by adjusting the irradiation time, the energy density thereof, for example, red light having a wavelength of 635.+ -. 5nm, can be adjusted. There is a great deal of evidence that when the blood product is irradiated by weak light, light quanta in the laser are absorbed by components in the blood product and converted into internal energy, so that the effect of activating the components in the blood product is achieved, and the blood product can keep certain activity in an active mode, namely, a certain retarding or blocking effect is achieved on the inactivation trend of blood cells, or certain quantity, property and state change are obtained. Red light can also enhance the immune function of red blood cells. Thereby further improving the preservation quality of the blood product under the same preservation period or prolonging the preservation time of the blood product when the blood product is in a preservation environment. After the blood product is separated from the preservation environment, the activity of the components in the blood product can be maintained for a long time, so that the preservation time of the blood product after being separated from the specific preservation environment is prolonged, more treatable time is provided for clinical medical treatment, and the effect of operation or treatment is effectively improved. Meanwhile, the yield in the preservation and transportation processes can be improved, and even the quantity, the property and the function of blood components in the preservation can be changed and improved according to clinical expectations and demands.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are needed in the embodiments will be briefly described below, it being understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and other related drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic view of a blood product light energy storage bag according to an embodiment of the present invention;
FIG. 2 is a schematic diagram showing a second embodiment of a light energy storage bag for blood products;
FIG. 3 is a third schematic view of a light energy storage bag for blood products according to an embodiment of the present invention;
fig. 4 is a schematic diagram of a structure of a light energy storage bag for blood products according to an embodiment of the present invention.
Icon: 100-an outer bag body; 101-an inner bag body; 102-a lamp strip; 1021-a first light strip; 1022-a second light band; 103-a first connection; 104-a light emitting member; 105-communicating tube.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments of the present invention. The components of the embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the invention, as presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. It should be noted that, under the condition of no conflict, the features of the embodiments of the present invention may be combined with each other, and the combined embodiments still fall within the protection scope of the present invention.
It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further definition or explanation thereof is necessary in the following figures.
In the description of the present invention, it should be noted that the directions or positional relationships indicated by the terms "upper", "lower", "inner", "outer", etc. are merely for convenience in describing the present invention and for simplifying the description, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," "third," and the like are used merely to distinguish between descriptions and should not be construed as indicating or implying relative importance.
In one aspect of an embodiment of the present invention, and with reference to FIG. 1, there is provided a blood product light energy storage bag comprising: an inner bag 101 and an outer bag 100 wrapped around the inner bag 101; the inner bag 101 is used for accommodating blood products; an interlayer is formed between the outer bag 100 and the inner bag 101, and a light emitting assembly is disposed in the interlayer, and the light emitting assembly is used for emitting weak light toward the inner bag 101.
For example, as shown in fig. 1, an outer bag 100 is wrapped around the outside of an inner bag 101, and a sandwich, i.e., a cavity, is formed between the inner and outer bags. The light emitting component (i.e. the light strip 102 in fig. 1) is arranged in the interlayer, and the light emitting component is electrified, so that the light emitting component emits weak light, the weak light irradiates on the blood product in the inner bag body 101, and the biostimulation effect of the weak light on the blood product is utilized, namely, when the blood product is irradiated by the weak light, the light quanta in the laser can be absorbed by the components of the blood product and converted into internal energy, so that the effect of activating the components of the blood product is achieved, and the blood product can keep certain activity in an active mode, namely, the inactivation trend of the components of the blood product (the components inevitably die gradually after the blood product is separated from the body) plays a certain role in retarding or blocking. Therefore, when the blood products are in the preservation environment, the preservation quality of the blood products under the same preservation period can be further improved or the preservation time of the blood products can be prolonged, and the shortage of the blood products in the existing blood warehouse in quantity can be relieved to a certain extent due to the prolongation of the preservation time. After the blood product is separated from a specific preservation environment, weak light irradiation can be continuously provided for the blood product, the weak light irradiation is performed on the blood product, living cells in the blood product can be effectively activated and maintained, the yield of preservation and transportation of the blood product after the blood product is separated from the body can be improved, the blood product can be kept to have certain activity by means of the stimulation, further the preservation time is prolonged, more treatable time is provided for clinical medical treatment, and the effect of operation or treatment is effectively improved. Meanwhile, the blood product light energy storage bag in the application can be directly improved on the basis of the existing blood product storage bag, and is used as the inner bag body 101, and the outer bag body 100, the related light-emitting components and other structures are correspondingly arranged on the inner bag body, so that the blood product light energy storage bag has the related functions in the application, and has the advantages of simple structure and low manufacturing cost, and is suitable for being popularized and used in a large range.
When the blood product is irradiated by weak light, on the one hand, the activation of the weak light can reduce the alpha 1-antitrypsin and alpha 2-globulin level, so that the fibrinolytic system is activated and fibrinogen is reduced. Simultaneously, chromophores in the blood product can be activated and metabolized to be increased. Thus, components in the blood product are effectively activated, such as the structure and the function of cell membranes are changed, the distribution of membrane enzymes, receptors and surface charges is changed, the stability of the membrane is improved, and the deformability of red blood cells is enhanced.
On the other hand, when the blood product is left for a long period of time, coagulation occurs, mainly because of aggregation of erythrocytes in the blood product. The main factors affecting the aggregation index of erythrocytes are long-chain bridging between erythrocytes and reduction of the surface charge of erythrocytes, while the main factors affecting long-chain bridging between erythrocytes are fibrinogen content, and the more fibrinogen, the stronger bridging between erythrocytes, the stronger the aggregation ability of erythrocytes. Fibrinogen is produced primarily by the plasminogen-plasmin system, where plasminogen activator is composed of a variety of biological enzymes whose direction of displacement of protein molecules is specific, where the movement of the nuclei in the protein is in conformational motion, and the energy required to rotate about a single bond is much lower than the energy required to rotate about a long bond or change the angle between bonds. If the electron energy level changes, conformational movement of the nucleus occurs, and the electrons and conformational interaction result in the enzyme catalyzing, so that when the frequency of laser irradiation approaches the natural frequency of certain energy levels of the plasminogen activator molecule, electrons in the plasminogen activator molecule will transition between these energy levels. Thereby leading the nucleus in the plasmin activator molecule to move to generate allosteric effect, providing power for the fractal catalysis process of enzyme, activating the plasmin-plasmin system, decomposing more plasmin in plasma, dissolving the fibrin in plasma, reducing bridging fibrin acted between red blood cells, reducing the aggregation capability of the red blood cells, and simultaneously reducing the viscosity and blood sedimentation of blood. Meanwhile, as the activity of the red blood cells is increased, the immunity is improved, and the movement of the red blood cells is enhanced so as not to be easy to gather. Namely, the activity of components in the blood product is effectively improved by activating the activities of various enzymes, improving the rheology of blood, increasing the expression of related genes and the like.
Firstly, the weak light is distinguished by the intensity of biological effect generated after the weak light irradiates the biological tissue, and the weak light can be 280-10000nm, especially 380-2000nm, with the power output of 0.01-90mw/cm based on the irreversible damage to the target tissue (namely, the light which only positively and beneficially promotes and stimulates the biological tissue) 2 Between them. The laser light is not limited to stimulated radiation in this application, but may be other luminescence types of spontaneous radiation, etc., such as neon lights, fluorescent lights, LED lights, etc. For ease of understanding, the following will be described schematically by taking a weak laser (other types of light are similar to weak lasers) as an example (not to be understood as limiting the application), and the weak laser is not used for measuring the intensity of the laser by its own physical parameters in medicine, but is distinguished by the intensity of biological effects generated after the laser acts on biological tissues. The weak laser in the application refers to a laser with a weak response level which can not cause irreversible damage to target tissues when the organism is directly irradiated by low-intensity laser, and the laser stimulates the organism to generate a series of physiological and biochemical response reactions, plays a role in regulating, enhancing or inhibiting, and achieves the aim of activating cell activity. It is different from strong laser, and features low output energy and no light-heat effect, so that the local temp. rise caused by weak laser is not more than 0.1-0.75 deg.C, and the biological change of local tissue can not be caused. Weak laser generally refers to a power output of between 10 and 90mw and an energy density of between 1 and 4J/cm at the irradiation site 2
Second, the weak laser may be He-Ne laser (wavelength at 632.8 nm), gaAlAs laser (wavelength 820)830 nm), gaAs lasers (wavelength 904 nm), and so forth. Parameters of dim light: wavelengths are typically 632.8, 820, 830 or 904nm; the power is 10-90mw (a few can be less than 10mw or more than 100 mw); the waveform is continuous wave and pulse wave (1-4000 Hz); the energy density is 1-4J/cm 2
Third, the light emitting device may be a he—ne laser, a semiconductor laser, an LED lamp, or the like.
Fourth, the inner bag 101 and the outer bag 100 may be flexible bags, or the inner bag 101 may be a flexible bag, and the outer bag 100 may be a bag with a certain strength, so as to form a certain protection effect on the inner bag 101. For example, in one embodiment, the outer bag 100 and the inner bag 101 may be made of polyvinyl chloride (Polyvinyl chloride, PVC) material, which has the characteristics of high mechanical strength and good softness and elasticity. In addition, in another embodiment, the outer bag 100 and the inner bag 101 may be made of 1, 2-tetraphenyl ethylene (Thermoplastic Elastomer, TPE) which is mainly characterized by high elasticity, high strength and high rebound resilience, and at the same time, the main composition of the material is C 26 H 20 Therefore, the material also has the characteristics of environmental protection, no toxicity, safety, weather resistance, fatigue resistance, temperature resistance and the like. When the outer bag 100 is a bag having a certain strength, it may be made of polypropylene (PP), which has not only chemical resistance and good high abrasion resistance, but also toughness of high strength, so that the finished product thereof can have a certain strength, thereby forming good protection capability for the inner flexible inner bag 101.
Fifth, correspondingly, in order to further ensure the stability of the arrangement of the light emitting component, the light emitting component may be fixedly arranged or detachably arranged on the outer surface of the inner bag body 101, or may be fixedly arranged or detachably arranged on the inner surface of the outer bag body 100.
Further, for the arrangement form of the above-described light emitting assembly, one example is: the light-emitting component only comprises weak light with fixed wavelength and fixed power output, and is arranged in an interlayer between the inner bag body 101 and the outer bag body 100, when a blood product is arranged in the inner bag body 101, the light-emitting component can emit the weak light with the specific wavelength and the specific power output to the blood product by controlling a switch button connected with the light-emitting component to be in an open state, so that the effect of activating the activity of the components in the blood product is achieved. Because of the different blood components used for whole blood transfusion and component transfusion, blood products also generally include a variety of plasma products of different components, such as platelet products, clotting factor products, fibrinogen products, and the like. In order to further improve the effect of weak light on the activation of the blood products, the weak light which is more suitable for the blood products with different components can be arranged, so that the scientificity and the flexibility of the light energy storage bag for the blood products in the application are further improved from the aspect of using effect. Meanwhile, different marks corresponding to blood products with different components can be arranged on the outer surface of the outer bag body 100 of the blood product light energy storage bag, for example, different colors can be used for distinguishing, and colors, symbols, fonts and the like can be used for distinguishing, so that confusion is not easy to occur in actual use, and the convenience in use is improved.
Another embodiment: the light-emitting component comprises a plurality of low-light generators (which can be light bands 102 or light beads) with different wavelengths and different output powers, and the low-light generators are reasonably arranged in the interlayer (so that the blood products in the inner bag body 101 can be uniformly irradiated). Meanwhile, a mode selection knob, a touch screen, a mode key and the like can be further arranged on the outer bag body 100 and connected with the light-emitting component, so that the blood product light energy storage bag can flexibly select a corresponding mode according to the type of blood product filled in the blood product light energy storage bag during use, the activation effect of the blood product light energy storage bag can be improved, and the use range and the automation degree of the blood product light energy storage bag can be also improved. The following will schematically illustrate the mode selection knob, which corresponds to both a mode and B mode, and may be provided with an off mode, i.e. a power-off mode. In use, the corresponding mode may be selected according to the type of blood product being loaded. In addition, there may be four modes, five modes, etc. (as with the three modes described above) so that the blood product light energy storage bag of the present application can support a greater variety of different compositions of blood products. In order to further reduce the manufacturing and use costs, the outer bag 100 and the inner bag 101 may be detachably connected (e.g., by a connection such as a zipper or a velcro), and the manufacturing and use costs may be reduced by using the outer bag 100 and the light emitting assembly several times.
Optionally, the blood product light energy storage bag further includes a first connector 103, one end of the first connector 103 is connected to the outer surface of the inner bag body 101, and the other end is connected to the inner surface of the outer bag body 100.
For example, referring to fig. 2, a first connecting piece 103 is further disposed in the interlayer, and the inner bag body 101 is connected with the outer bag body 100 through the first connecting piece 103, so that a certain connection relationship is formed between the inner bag body and the outer bag body, and mutual rotation between the inner bag body 101 and the outer bag body 100 can be effectively prevented, so that phenomena such as winding and dislocation are avoided. Meanwhile, the weak light emitted by the light-emitting component can be more stable in irradiating the blood product, and the situation that the weak light emitted by the light-emitting component is difficult to effectively irradiate the blood product due to rotation between the inner bag body and the outer bag body in the transportation process and the like is avoided. The stability of the blood product light energy storage bag in the embodiment when the blood product is stored is improved, namely the yield of the blood product in transportation or use is improved. It should be noted that the form of the first connector 103 may be various, and there are no specific restrictions in this application, and two of them will be schematically shown by way of example below:
as shown in fig. 2, when the first connecting piece 103 is a glue column, a plurality of first connecting pieces can be arranged in the interlayer, the arrangement positions can be as shown in fig. 2, only one circle of first connecting pieces is arranged between the inner bag body 101 and the outer bag body 100, the arrangement mode can effectively save raw materials, reduce manufacturing cost, and is suitable for scenes with weaker vibration environments, for example, blood collection is performed in a blood donation point, and after collection is completed, the blood product light energy storage bag in the application is placed in a low-temperature environment of a blood station blood bank for storage, so that subsequent use is facilitated. Meanwhile, the setting positions can be uniformly distributed along the outer surface of the inner bag body 101, so that the inner bag body and the outer bag body can be uniformly limited at each position through the connection of the rubber columns, relative shaking between the two bag bodies is reduced, the device is suitable for scenes with stronger vibration environments, for example, after collection is completed, the device is placed on a place meeting the regulations for storage, and then long-distance transportation is needed when transportation is needed, the strength of the bag bodies can be enhanced, and the yield of blood products in transportation is further improved.
The inner bag 101 in the present application may be a conventional blood storage bag, and a transparent bag is generally used. Meanwhile, the outer bag 100 may be provided as an openable and closable bag, and the specific form of opening and closing may be that one side has an opening, or that three sides have openings (in this form, when opening, the opposite side walls of the outer bag 100 may be completely spread with the fourth side as a rotation center), and then the existing blood storage bag is placed therein, and the side of the outer bag 100 provided with the opening is closed, thereby achieving weak light irradiation. The convenience in use is further improved, and the cost in use can be effectively reduced.
In addition, the first connecting member 103 may be a protrusion provided on the inner wall of the outer bag 100 and a groove provided on the outer wall of the inner bag 101, respectively, so that the outer bag 100 and the inner bag 101 form a stable connection relationship by interference fit of the protrusion and the groove. At the same time, the inner bag body 101 and the outer bag body 100 are convenient to split when needed. Alternatively, the light emitting assembly is a light band 102, and the light band 102 is disposed around the outer circumference of the inner bag 101.
For example, as shown in fig. 1, the light emitting component may be a light band 102, that is, emits weak light in a manner of using a linear light source, and in order to enable the light band 102 to have a good biostimulation effect on the blood product in the inner bag 101, the light band 102 may be disposed in a manner of surrounding the outer circumference of the inner bag 101. Thereby ensuring that the blood product in the inner bag 101 is always well irradiated with weak light. The manner in which the light band 102 surrounds the inner bag 101 is not particularly limited, and may be, for example, a spiral winding manner or a manner in which a plurality of annular bands are wound in the following embodiments. So long as it can ensure that the blood product is always irradiated with a sustained weak light.
Alternatively, the light strip 102 includes a first light strip 1021 and a second light strip 1022, the first light strip 1021 is wound around the outer circumference of the inner bag 101 in a first direction, and the second light strip 1022 is wound around the outer circumference of the inner bag 101 in a second direction, the first direction and the second direction intersecting.
For example, the light bands 102 may further include a plurality of light bands 1021 around the outer circumference of the inner bag 101 along the first direction, as shown in fig. 3, when the first light bands 1021 are provided in a spiral wound form, only one light band may be provided, and in order to further improve uniformity of weak light irradiation, the second light bands 1022 may also be provided in one light band, and directions in which the two light bands 102 spirally extend intersect, so that uniform weak light irradiation is formed on the blood product in the inner bag 101 in a crossed structure, wherein, in order to ensure the overall irradiation, both the starting end and the ending end of the first light band 1021 and the second light band 1022 should be provided at positions of both ends of the inner bag 101. In this embodiment, the inner bag 101 may be an existing blood bag (the existing blood bag is a bag similar to an infusion bag and is generally made of transparent plastic), and is combined with the outer bag 100, so that the first light band 1021 and the second light band 1022 may be disposed on the inner wall of the outer bag 100 for further improving the recycling rate of the outer bag 100 and the convenience of replacement of the inner bag 101, but the light emitting directions of the first light band 1021 and the second light band 1022 are corresponding to the blood products in the inner bag 101. Thereby not only improving the yield of the blood products, but also effectively reducing the manufacturing cost of the blood product light energy storage bag, and being convenient for the large-scale application of the blood product light energy storage bag.
When the ring-shaped winding is performed in the manner of fig. 1, in order to ensure that the blood product in the inner bag 101 is uniformly irradiated with weak light, a plurality of first lamp bands 1021 may be provided and may be disposed in parallel with each other. Similarly, the second light strips 1022 may be disposed in parallel with each other. And the corresponding first lamp strip 1021 and second lamp strip 1022 are perpendicular (not shown), so that a grid-shaped irradiation structure (refer to a grid-shaped structure in which the first direction and the second direction are intersected in fig. 3) is formed, and the requirement of the blood product on uniform weak light irradiation is met. Meanwhile, when the inner bag 101 is an existing blood bag, the first and second lamp bands 1021 and 1022 may be provided on the inner wall of the outer bag 100, as required when the above spiral arrangement is required.
Optionally, the light emitting assembly includes a plurality of light emitting members 104 disposed on the inner surface of the outer bag 100, and the plurality of light emitting members 104 are uniformly disposed along the inner surface of the outer bag 100.
For example, as shown in fig. 4, the light emitting assembly may also be a plurality of light emitting members 104 disposed on the inner surface (i.e. inner wall) of the outer bag 100, that is, a point light source is used to emit weak light, such as LED lamp particles. The bag is integrated with the outer bag body 100, so that the space required by the interlayer can be reduced, the space utilization rate of the inner bag body 101 is improved, and the volume of the blood product light energy storage bag is effectively reduced. Meanwhile, when the outer bag 100 is a flexible bag, it is also possible to have as little influence on the flexibility thereof as possible. In order to enable the blood products stored in the inner bag 101 to be uniformly and stably irradiated with weak light, a plurality of LED lamp particles can be uniformly arranged on the inner wall of the outer bag 100, so that the same weak light can be emitted to the inner bag 101 from all angles in the electrified state. It should be noted that, the light emitting member 104 may be disposed on a side wall of the inner wall of the outer bag 100, and when in use, the side wall provided with the light emitting member 104 should be disposed downward, that is, in fig. 4, the light energy storage bag for blood products is turned over by 180 degrees, so that weak light irradiates from bottom to top, and blood can be uniformly received. Further, the luminous elements 104 may be provided on the inner walls of both sides of the outer bag 100.
Optionally, an insulation layer is further provided on the outer bag 100.
For example, in order to further improve the yield and preservation time of the blood product, an insulation layer may be disposed on the outer bag 100, so that the inner bag 101 wrapped in the outer bag 100 is at a suitable temperature for preservation as much as possible, and in combination with the weak light irradiation in the foregoing embodiment, the preservation time of the blood product may be effectively improved. It should be noted that, the heat insulation layer may be made of heat insulation material of the outer bag 100, or may be a heat insulation structure layer provided on an outer wall of the outer bag 100, or a heat insulation structure layer provided on an inner wall of the outer bag 100, or may be provided on both sides of the outer bag 100.
Optionally, the inner bag 101 is a transparent bag, and the outer bag 100 is a light shielding bag.
For example, in order to further increase the illuminable area of the inner bag 101, so that weak light can provide stable illumination for each blood product, the inner bag 101 may be configured as a transparent bag (i.e., a transparent material through which light can pass). In order to avoid the deterioration of the blood product caused by the direct irradiation of external light, the outer bag 100 may be a light-shielding bag (i.e. opaque material), so that the biological stimulation of weak light is utilized to prolong the preservation time of the blood product in the inner bag 101 and avoid the influence of external light on the blood product. It should be noted that, in this embodiment, the inner bag 101 may be an existing blood bag, and may be combined with the light-shielding outer bag 100 (may be provided with the first connector 103, the light band 102, the light emitting member 104, etc. in other embodiments), so as to improve the yield of the blood product and the application range of the blood product light energy storage bag in this embodiment. Meanwhile, besides the above-mentioned material that the outer bag body 100 body is made of opaque material, a light shielding layer may be further disposed on the outer bag body 100, where the light shielding layer may reflect light or absorb light, so as to achieve the purpose of shielding light.
Optionally, an observation window is further disposed on the outer bag 100 near the output end.
For example, an observation window may be further provided on the light-shielding outer bag 100, so that a medical care or an operator can observe the relevant status information of the blood product in the inner bag 101 from the outside through the observation window, for example, observe the residual amount of the blood product in the inner bag 101 through the observation window, or observe whether the color of the blood product in the inner bag 101 is normal through the observation window, and primarily judge whether the blood product is deteriorated. The observation window can be a hollowed window, can be square, rectangle, round and the like, and can be 0.5 square centimeter, 1 square centimeter and the like; the observation window can also be composed of a hollowed-out area and a cover plate made of transparent materials, wherein the size of the hollowed-out area is matched with that of the hollowed-out area, so that the inner part of the outer bag body 100 is sealed, and the dustproof and waterproof capabilities of the outer bag body are enhanced. In addition, in order to be convenient for control the state when using, and because blood bag its output when using down, the blood product in the internal bag body 101 is through the output through the transfer line into the patient in, so, can set up the position setting of viewing window in the one side that is close to the output to be convenient for control the surplus of blood product in the blood product light energy storage bag. The specific position, size and specific form of the observation window are not limited in the application.
Optionally, the blood product light energy storage bag further comprises a storage battery, the storage battery is arranged in the interlayer, and the storage battery is electrically connected with the light emitting component.
For example, a battery may be further provided in the interlayer between the inner bag 101 and the outer bag 100, and the battery may be electrically connected to the light emitting module to supply power to the light emitting module under certain conditions. In addition, a switch can be arranged between the storage battery and the light-emitting component, and whether the light-emitting component emits weak light can be controlled by controlling the on and off of the switch. Meanwhile, the control switch can also be an adjusting switch, so that the light emitting component is controlled to emit weak light with different powers through the position of the adjusting switch. The storage battery may be a chargeable and dischargeable storage battery, and the outer bag 100 is provided with a charging interface electrically connected to the chargeable and dischargeable storage battery, so that the storage battery may be directly charged by external charging when necessary. And the tedious operation of frequently replacing the storage battery is avoided.
Optionally, a communicating pipe 105 is provided on the inner bag 101, the communicating pipe 105 passes through the outer bag 100 to communicate with the outside, and a sealer is provided at a pipe orifice of the communicating pipe 105.
As an example, as shown in fig. 4, a communicating pipe 105 may be further disposed on the inner bag 101, one end of the communicating pipe 105 is communicated with the inner space of the inner bag 101, and the other end is communicated with the outside, that is, one end of the communicating pipe 105 extends into the inner bag 101, and the other end passes through the interlayer between the outer bag 100 and the inner bag 101 and the structure of the bag wall of the outer bag 100 body. In order to ensure the tightness of the inner space of the inner bag 101, a sealer may be provided at the spout of the end of the communication tube 105 communicating with the outside. The sealer may be medical grade polyvinyl chloride (PVC), medical rubber, etc., and may be wrapped around the outer wall of the communication tube 105, or may be filled in the internal passage of the communication tube 105.
In actual use, when blood products need to be input into the inner bag 101, an operator firstly removes the sealer at the orifice of the communicating tube 105, then communicates one end of the communicating tube 105, which communicates with the outside, with the blood products, and guides the blood products to flow into the space in the inner bag 101 through the pipe of the communicating tube 105, and finally installs the sealer at the orifice, thereby completely sealing the inner space of the inner bag 101. When the blood product is required to be output to the outside, the infusion tube may be directly inserted into the sealer, so that the blood inside the inner bag 101 is output to the outside through the infusion tube. The sealer may be removed from the orifice of the communication pipe 105 and then output to the outside. Through the arrangement of the communicating pipe 105 and the sealer, an operator can conveniently input blood products into the inner bag body 101 or output the blood products in the inner bag body 101 to the outside, and good tightness of the blood products in the inner bag body 101 can be further ensured.
The above description is only of the preferred embodiments of the present invention and is not intended to limit the present invention, but various modifications and variations can be made to the present invention by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (6)

1. A blood product light energy storage bag comprising: an inner bag body and an outer bag body wrapped with the inner bag body; the inner bag body is used for accommodating blood products; an interlayer is formed between the outer bag body and the inner bag body, and a luminous layer is arranged in the interlayerThe light-emitting component is used for emitting weak light towards the inner bag body, the wavelength of the weak light is 380-2000nm, and the power output of the weak light is 10-90mw/cm 2 The energy density of the weak light is 1-4J/cm 2 So that the local temperature rise caused by the weak light is not more than 0.1-0.75 ℃;
the outer bag body is detachably connected with the inner bag body; the inner bag body is a transparent bag body, the outer bag body is a shading bag body, the shading bag body is used for reflecting light, and the inner bag body and the outer bag body are flexible bag bodies; the bag further comprises a first connecting piece, wherein one end of the first connecting piece is connected with the outer surface of the inner bag body, and the other end of the first connecting piece is connected with the inner surface of the outer bag body;
the light-emitting assembly comprises a sandwich layer, a light-emitting assembly, a storage battery and a control circuit, wherein the sandwich layer is arranged between the light-emitting assembly and the storage battery;
and an observation window is further arranged on the outer bag body close to the output end.
2. A blood product light energy storage bag according to claim 1 wherein the light emitting assembly is a light strip disposed around the outer periphery of the inner bag body.
3. A blood product light energy storage bag according to claim 2, wherein the light strip comprises a first light strip and a second light strip, the first light strip being wrapped around the outer periphery of the inner bag body in a first direction, the second light strip being wrapped around the outer periphery of the inner bag body in a second direction, the first direction and the second direction intersecting.
4. A blood product light energy storage bag according to claim 1 wherein the light emitting assembly comprises a plurality of light emitting members disposed on the inner surface of the outer bag body, the plurality of light emitting members being disposed uniformly along the inner surface of the outer bag body.
5. A blood product light energy storage bag according to claim 1, wherein a heat insulating layer is further provided on the outer bag body.
6. A blood product light energy storage bag according to any one of claims 1 to 5 wherein a communicating tube is provided on the inner bag body, the communicating tube communicating with the outside through the outer bag body, and a sealer is provided at the mouth of the communicating tube.
CN202010562430.8A 2020-06-18 2020-06-18 Light energy storage bag for blood products Active CN111544296B (en)

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