CN101564350A - Soft package of instantaneous matching type medical inner bag with a plurality of chambers - Google Patents
Soft package of instantaneous matching type medical inner bag with a plurality of chambers Download PDFInfo
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- CN101564350A CN101564350A CNA2008100932477A CN200810093247A CN101564350A CN 101564350 A CN101564350 A CN 101564350A CN A2008100932477 A CNA2008100932477 A CN A2008100932477A CN 200810093247 A CN200810093247 A CN 200810093247A CN 101564350 A CN101564350 A CN 101564350A
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Abstract
The invention provides a soft package (1)of an instantaneous matching type medical inner bag with a plurality of chambers. The soft package (1) comprises an outer bag (2) and an inner bag (3); the outer bag (2) separates the inner bag (3) from the outside; the inner bag (3) is provided with a combined cover (12) used for sealing; the combined cover (12) comprises an infusing part (5), one end of the infusing part (5) is hermetically arranged on an opening (17) of an inner bag body (4); and inner holes communicated with the inner bag (3) are disposed along the length direction of the infusing part (5). The soft package is characterized in that the inner bag (3) also comprises at least one easy-open type separation zone (20); the easy-open type separation zone divides the inner bag (3) into at least two chambers (4, 8); the chambers are respectively used for storing different medicaments; and inactive gas is filled in an isolated space between the outer bag (2) and the inner bag (3).
Description
Technical field
The present invention relates to a kind of flexible package, particularly the flexible package of relevant a kind of instant matched medical multicell inner bag with powder charge product inner bag.
Background technology
Usually a lot of drug containers are only adorned a kind of medicine, infusion vessel especially, and in this container, add other medicine in use as required, and this is that undesirable timeliness changes or reaction because some medicaments are if can occur when cooperating in advance.Concerning liquid-liquid mixing is used, for example cooperate amino acid transfusion and glucose infusion liquid the back to preserve in advance, long meeting of mixed liquor time one produces reaction and brown stain.Mix use for powder-liquid, for example the powdery antibiotic has only when use just to add mixing with it in the transfusion to, otherwise curative effect and safety just are a problem.The way of generally adding medicament at present is to adopt the dosing needle tubing, complete operation process under aseptic condition, and need repeat repeatedly just can finish, extremely inconvenient.
For overcoming the above problems, a lot of trials have been done in the industry, just disclose the soft bag of powder-liquid and liquid-liquid double-chamber transfusion respectively as Chinese utility model 03253629.1 and 200520126797.6, be respectively equipped with the preserving chamber of preserving two kinds of medicaments, each preserving chamber is isolated by isolating with soft closure.Mix under aseptic condition by opening the isolation sealing of isolating each preserving chamber, make the medicament that is kept in each preserving chamber during use.
Yet above-mentioned packed in flexible pouchy is a kind of simple packing, allows promptly join operation safely and easily between the medicament in a soft bag, does not but solve timeliness effect or the reaction problem of packing to single medicament itself.
Present jumbo Western medicine medicinal liquid generally adopts PVC and non-PVC bag.Because all the transit dose to steam and oxygen is bigger for medicinal PVC and non-PVC composite membrane, to the steady quality generation adverse influence of medicinal liquid (comprising herb liquid), shortened the quality guarantee period of medicine, reduced the safety of medicine.In addition, adopt simple flexible package in being transported to a series of processes of use, to damage easily at present, also brought unsafe factor.
For this reason, application number is that 200710017686.5 Chinese patent application has been done some trials, it relates to the outer package application that nontoxic clad aluminum foil is used for PVC or the packed infusion preparation of non-PVC-soft, this application adopts double casing, in inner packing, outer package is opaque composite aluminium film bag with liquid medicine filling, puts into different types of PVC or packed infusion preparation of finishing of non-PVC-soft of having packed in the bag, add antioxidant simultaneously and charge into nitrogen or evacuation, compound membrane bag seals the most at last.Opaque material is adopted in the outer package of this application, can't carry out medically necessary clarity test.In addition, must add antioxidant and nitrogen simultaneously between two bags, or add antioxidant and evacuation simultaneously, the latter is unfavorable for shockproof and protection to internal bag.Also have, the influence to the pH value of some medicinal liquid under higher temperature of the outer bag of nontoxic clad aluminum foil is bigger, and especially Chinese medicine as SHENQI FUZHENG ZHUSHEYE, Oleum Curcumae medicinal liquid or Radix Notoginseng total glycosides preparation etc., is unfavorable for promoting the use of.
Summary of the invention
Therefore, task of the present invention is a kind of flexible package of instant matched medical multicell inner bag, it adopts the inflatable structure between inner bag and the outer bag, can intercept steam and oxygen effectively, prolonged the quality guarantee period of medicament, improved the safety that medicament uses, and had and be convenient to transportation and non-damageable advantage.
For this reason, the invention provides a kind of flexible package of instant matched medical multicell inner bag, comprise outer bag and inner bag, described outer bag separates the inner bag and the external world; Inner bag has the composite cover of sealing; Described composite cover comprises infusion spare, one end of this infusion spare is encapsulated on the opening of inner bag body, and this infusion spare has the endoporus that is communicated with inner bag at its length direction, it is characterized in that: inner bag also comprises at least one easy-opening seal isolation band, described at least one easy-opening seal isolation band is divided at least two chambers with inner bag, be used for storing different medicaments respectively, and and outside described the bag and inner bag between be filled with inertness gas in the insulating space.
According to the present invention, described inertness gas is nitrogen or noble gas.Also can be added with oxygen absorbent or desiccant in by insulating space described.Described at least one easy-opening seal isolation band is the weak tape splicing of being made up of heat-sealable area.Certainly, also tape splicing a little less than the weak tape splicing of cold enclosed and/or the cold enclosed formed by convex strip portions and recessed portion of easy-opening seal isolation band.Described easy-opening isolation strip also can be compound easy-opening seal isolation band.
The applicant finds, is filled with inertness gas in the sealed space outside described between bag and the inner bag and just intercepts steam and oxygen basically effectively.Inertness gas can be nitrogen, also can be noble gas.Add oxygen absorbent and can further strengthen above effect.
Be understood that, be filled with gas in the sealed space between bag and the inner bag outside and help damping and insulation blocking, particularly in transportation, improved the safety of medicine.
According to a further general feature of the present invention, outer bag and inner bag are transparent, and described inner bag is made by non-PVC composite membrane, and outer bag is selected PE film material for use.
In addition, the outer surface both sides that the chamber of powder medicine is housed are attached with lighttight thin film, and at least one layer film can be peeled off.
Description of drawings
Below, further describe the present invention referring to accompanying drawing, wherein:
Fig. 1 is the sketch map according to the flexible package of instant matched medical multicell inner bag of the present invention;
Fig. 2 is the exploded view of first embodiment of the inner bag of medical liquor soft package shown in Figure 1, and wherein composite cover up;
Fig. 3 is second embodiment front view of the inner bag of medical liquor soft package shown in Figure 1, and wherein composite cover down;
Fig. 4 is the cutaway view of second embodiment of inner bag shown in Figure 3 along the A-A line;
Fig. 5 is the cutaway view of the isolation strip between each chamber of inner bag of the present invention;
Fig. 6 is the cutaway view of the isolation strip between each chamber of another kind of inner bag of the present invention.
The specific embodiment
At first with reference to Fig. 1, it shows the sketch map of the flexible package of instant matched medical multicell inner bag of the present invention.Described packing is totally represented with 1, comprises the outer bag 2 and the inner bag 3 of band tearing port 9, and they are by transparent material.Inner bag 3 comprises an easy-opening seal isolation band 20, and inner bag 3 is divided into two chambers 4,8, is used for storing two kinds of different medicaments respectively.This isolation strip 20 can be opened, and makes can mix in inner bag 3 between the medicament in order to using.Inner bag 3 also has the composite cover 12 with the inner bag sealing.Described inner bag 3 is generally made by known medical non-PVC composite membrane.Outer bag 2 can be made by the high barrier material with resistance oxygen water resistance characteristic.As a kind of selection, the material of outer bag 2 also can be the same with the material of inner bag 3.
Fig. 2 is the exploded view of first embodiment of the inner bag of medical liquor soft package shown in Figure 1, and wherein chamber 4,8 is used to store two kinds of different medicinal liquids.Described composite cover 12 further comprise cover 6, infusion spare 5 and the plug 18 between lid 6 and infusion spare 5, see also Fig. 2.The structure of infusion spare 5 is structure commonly used.One end of this infusion spare 5 is encapsulated on the opening 17 of inner bag body 4, and this infusion spare 5 has the endoporus that is communicated with inner bag 3 at its length direction.Infusion spare 5 and plug 18 are made by known medical material, and wherein the material of infusion spare 5 can be identical or inequality with the material of inner bag 3.If it is inequality, preferably chemical compatible.If chemistry is inconsistent, then compatilizer is added at least wherein a kind of material, be used to improve two kinds of bond vitrifieds between the material.
For ease of filling, be provided with closed infusion tube 7 at the edge of the chamber 8 of an end opposite with composite cover 12.Certainly, a closed infusion tube also can be established in addition in 4 edge in the chamber, but has generally been replaced by infusion spare 5.
The effect of outer bag 2 is with inner bag 3 and isolated from atmosphere.The material of outer bag 2 is the material with resistance oxygen, water preventing ability, but transparent, to use lamp inspection.Be filled with inertness gas in the insulating space between this external described outer bag 2 and the inner bag 3.Inertness gas is preferably nitrogen, but noble gas also suits.
The applicant finds, is filled with inertness gas in the sealed space outside described between bag and the inner bag and just intercepts steam and oxygen basically effectively.
After taking above measure, just can intercept steam and oxygen effectively.In order to reach better effect, consider the oxygen that the residual oxygen that may occur or infiltration are come in, between inner bag 3 and outer bag 2, add oxygen absorbent, even put into desiccant etc.These are all at thought range of the present invention.
Please referring to Fig. 3 and 4, be second embodiment of the inner bag of medical liquor soft package shown in Figure 1, wherein chamber 8 is used to adorn powder medicine 25, and generally is used for liquid drug 26 near the chamber 4 of composite cover 12.The structure of inner bag 3 is the same with first embodiment basically, and two outsides that difference is to adorn the chamber 8 of powder medicine are attached with lighttight thin film 23 and 22, because a lot of powder medicine need keep in Dark Place.In addition, at least one layer film 23,22nd can be peeled off.As shown in Figure 4, easy-opening seal isolation band is the weak tape splicing 20a that is made up of heat-sealable area, and this also is applicable to first embodiment.Just can open this weak tape splicing 20a that forms by heat-sealable area by extruding inner bag 3.
Fig. 5 and 6 shows other version of easy-opening seal isolation band respectively, belongs to the weak tape splicing of cold enclosed.As shown in Figure 5, the cross section is set on the side's pellicular front 3a in one of pellicular front in opposite directions in inner bag 3 is circular convex strip portions 27, simultaneously recessed the portion 28 that the cross section is a U-shaped is set on the opposing party's face 3b, constitutes easy-opening seal isolation band 20b by the releasable cooperation of strain.The benefit of this isolation strip is, constituting under the situation of easy-opening seal isolation band 20a by the pellicular front heat seal, for example if medicament powder or drop are dispersed to heat seal face, often can not get enough heat sealing strengths.In contrast, if adopt the isolation strip 20b of described concavo-convex cooperation,, also can obtain to seal reliably intensity even disperse under the situation of convex strip portions 27 and recessed portion 28 at medicament.
Just can increase Kaifeng intensity by the wall thickness that strengthens recessed portion 28.In addition, be provided with at the mating surface of convex strip portions 27 or recessed portion 28 and small concavo-convexly also can strengthen Kaifeng intensity.
The shape of convex strip portions 27 and recessed portion 28 is not subjected to above-mentioned restriction, as long as convex strip portions 27 and recessed portion 28 releasably cooperate.For example in Fig. 6, the cross section of convex strip portions 27 is hook-type, recessed portion 28 is set to have the fastening piece 28a that convex strip portions 27 is fastened simultaneously, thereby constitutes easy-opening seal isolation band 20c.Need to prove, be installed on pellicular front 3a, the 3b after convex strip portions 27 and recessed portion 28 can make separately, also can be integrally formed with pellicular front 3a, 3b respectively.If desired, with convex strip portions 27 and recessed the 28 corresponding pellicular front 3a of portion, be provided with respectively on the outer surface of 3b and be convenient to grab the device of pinching, for example draw ring 29, are convenient to open the seal isolation band.
The insider understands, can adopt a kind of compound easy-opening seal isolation band, is used for more reliable sealing.The sealing isolation strip is made up of the isolation strip 20b as shown in Figure 5 of two vicinities.Described two isolation strip can also be forms shown in Figure 6 or be made up of the isolation strip 20a of weak heat seal.In addition, this compound easy-opening seal isolation band also can be by above isolation strip 20a, and the combination in any of 20b and 20c also is a spirit according to the invention.
If do not consider clarity test, outer bag 2 can use opaque material, is in the light being used for.But the applicant finds, if adopt nontoxic clad aluminum foil, its influence to the pH value of some medicinal liquid under higher temperature is bigger, and Chinese medicine especially is as SHENQI FUZHENG ZHUSHEYE, Oleum Curcumae medicinal liquid or Radix Notoginseng total glycosides preparation.Therefore, the applicant does not recommend nontoxic clad aluminum foil to be used for the present invention.
Should be appreciated that it is exemplary and nonrestrictive more than describing.For having read those skilled in the art described above, many embodiment except given example and application will be conspicuous.For example the isolation strip of the present invention's employing can be more than two, thereby isolates at least three chambers, is used at least three kinds of different liquors of fill and/or powder.A kind of form or multi-form combination can be adopted in described isolation strip.Thus, protection scope of the present invention determine should not be limited to above description, but should determine with reference to follow-up claim and whole whole schemes that are equal to, can predict and expect that should give such claim.
Claims (10)
1. the flexible package (1) of an instant matched medical multicell inner bag comprises outer bag (2) and inner bag (3), and described outer bag (2) separates inner bag (3) with the external world; Inner bag (3) has the composite cover (12) of sealing; Described composite cover (12) comprises infusion spare (5), one end of this infusion spare (5) is encapsulated on the opening (17) of inner bag body (4), and this infusion spare (5) has the endoporus that is communicated with inner bag (3) at its length direction, it is characterized in that: inner bag (3) also comprises at least one easy-opening isolation strip (20), described at least one easy-opening isolation strip (20) is divided at least two chambers (4 with inner bag (3), 8), be used for storing different medicaments respectively, and and outside described, be filled with inertness gas in the insulating space between bag (2) and the inner bag (3).
2. packing according to claim 1 (1) is characterized in that, described inertness gas is nitrogen.
3. packing according to claim 1 (1) is characterized in that, described inertness gas is noble gas.
4. packing according to claim 1 (1) is characterized in that, is added with oxygen absorbent described in by insulating space.
5. packing according to claim 1 (1) is characterized in that, outer bag (2) and inner bag (3) are transparent, and the material of described outer bag (2) is the material with resistance oxygen, water preventing ability.
6. packing according to claim 1 (1) is characterized in that, and tape splicing a little less than weak tape splicing (20a) that described easy-opening isolation strip (20) is formed for heat-sealable area and/or the cold enclosed formed by convex strip portions (27) and recessed portion (28) (20b, 20c).
7. packing according to claim 1 (1) is characterized in that, at least one chamber (8) are equipped with powder medicine.
8. packing according to claim 7 (1) is characterized in that, the described outer surface both sides that the chamber (8) of powder medicine is housed are attached with lighttight thin film (23) and (22).
9. packing according to claim 8 (1) is characterized in that, the described lighttight thin film of one deck (23,22) can be peeled off at least.
10. packing according to claim 1 (1) is characterized in that, described easy-opening isolation strip (20) is compound easy-opening seal isolation band.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100932477A CN101564350A (en) | 2008-04-23 | 2008-04-23 | Soft package of instantaneous matching type medical inner bag with a plurality of chambers |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100932477A CN101564350A (en) | 2008-04-23 | 2008-04-23 | Soft package of instantaneous matching type medical inner bag with a plurality of chambers |
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| Publication Number | Publication Date |
|---|---|
| CN101564350A true CN101564350A (en) | 2009-10-28 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008100932477A Pending CN101564350A (en) | 2008-04-23 | 2008-04-23 | Soft package of instantaneous matching type medical inner bag with a plurality of chambers |
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| CN (1) | CN101564350A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102600187A (en) * | 2011-01-19 | 2012-07-25 | 四川科伦药物研究有限公司 | Amino acid glucose injection packaged by double-cavity bag and preparation method thereof |
| CN105287205A (en) * | 2014-06-20 | 2016-02-03 | 华仁药业股份有限公司 | Packaging method for amino acid injection |
| CN106344405A (en) * | 2015-12-29 | 2017-01-25 | 广州市健之堂医疗器械有限公司 | Precision filtering infusion container |
| WO2017107601A1 (en) * | 2015-12-26 | 2017-06-29 | 胡绍勤 | Sealing device |
| WO2017113905A1 (en) * | 2015-12-29 | 2017-07-06 | 胡绍勤 | Infusion container |
| CN109078214A (en) * | 2018-10-09 | 2018-12-25 | 刘伶俐 | Sputum chlorination equipment and sterilization method for respiratory passage infectious disease patients |
| CN111544296A (en) * | 2020-06-18 | 2020-08-18 | 四川省人民医院 | Blood products light energy keeps bag |
-
2008
- 2008-04-23 CN CNA2008100932477A patent/CN101564350A/en active Pending
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102600187A (en) * | 2011-01-19 | 2012-07-25 | 四川科伦药物研究有限公司 | Amino acid glucose injection packaged by double-cavity bag and preparation method thereof |
| CN102600187B (en) * | 2011-01-19 | 2014-07-02 | 四川科伦药物研究有限公司 | Amino acid glucose injection packaged by double-cavity bag and preparation method thereof |
| CN105287205A (en) * | 2014-06-20 | 2016-02-03 | 华仁药业股份有限公司 | Packaging method for amino acid injection |
| WO2017107601A1 (en) * | 2015-12-26 | 2017-06-29 | 胡绍勤 | Sealing device |
| WO2017107602A1 (en) * | 2015-12-26 | 2017-06-29 | 胡绍勤 | Sealed device |
| CN106344405A (en) * | 2015-12-29 | 2017-01-25 | 广州市健之堂医疗器械有限公司 | Precision filtering infusion container |
| WO2017113904A1 (en) * | 2015-12-29 | 2017-07-06 | 胡绍勤 | Precision filtering infusion container |
| WO2017113905A1 (en) * | 2015-12-29 | 2017-07-06 | 胡绍勤 | Infusion container |
| CN109078214A (en) * | 2018-10-09 | 2018-12-25 | 刘伶俐 | Sputum chlorination equipment and sterilization method for respiratory passage infectious disease patients |
| CN111544296A (en) * | 2020-06-18 | 2020-08-18 | 四川省人民医院 | Blood products light energy keeps bag |
| CN111544296B (en) * | 2020-06-18 | 2024-03-12 | 四川省人民医院 | Light energy storage bag for blood products |
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Application publication date: 20091028 |