CN111526873B - 用于调节微生物定殖的经取代的二苯乙炔 - Google Patents

用于调节微生物定殖的经取代的二苯乙炔 Download PDF

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Publication number
CN111526873B
CN111526873B CN201880055664.4A CN201880055664A CN111526873B CN 111526873 B CN111526873 B CN 111526873B CN 201880055664 A CN201880055664 A CN 201880055664A CN 111526873 B CN111526873 B CN 111526873B
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formulation
group
penicillin
compounds
antibiotic
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CN201880055664.4A
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Chinese (zh)
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CN111526873A (zh
Inventor
K·M·麦克圭勒
C·蔡
E·L·普罗茨尼克
A·M·麦克科米克
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Bio Mandix Co ltd
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Bio Mandix Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
    • A01N35/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aldehyde or keto groups, or thio analogues thereof, directly attached to an aromatic ring system, e.g. acetophenone; Derivatives thereof, e.g. acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Enzymes And Modification Thereof (AREA)
CN201880055664.4A 2017-07-27 2018-07-26 用于调节微生物定殖的经取代的二苯乙炔 Active CN111526873B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762537661P 2017-07-27 2017-07-27
US62/537,661 2017-07-27
US201862676676P 2018-05-25 2018-05-25
US62/676,676 2018-05-25
PCT/US2018/043833 WO2019023425A1 (en) 2017-07-27 2018-07-26 SUBSTITUTED TOLANES FOR THE MODULATION OF MICROBIAL COLONIZATION

Publications (2)

Publication Number Publication Date
CN111526873A CN111526873A (zh) 2020-08-11
CN111526873B true CN111526873B (zh) 2025-03-04

Family

ID=65040339

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880055664.4A Active CN111526873B (zh) 2017-07-27 2018-07-26 用于调节微生物定殖的经取代的二苯乙炔

Country Status (13)

Country Link
US (2) US11351126B2 (https=)
EP (1) EP3658128A4 (https=)
JP (1) JP7266597B2 (https=)
KR (1) KR102620652B1 (https=)
CN (1) CN111526873B (https=)
AU (1) AU2018306420B2 (https=)
BR (1) BR112020001619A2 (https=)
CA (1) CA3070427A1 (https=)
IL (1) IL272188B (https=)
MX (1) MX2020001043A (https=)
MY (1) MY204404A (https=)
SG (1) SG11202000708SA (https=)
WO (1) WO2019023425A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11351126B2 (en) * 2017-07-27 2022-06-07 BioMendics, LLC Substituted tolans for the modulation of microbial colonization
KR102407606B1 (ko) * 2020-04-27 2022-06-10 경희대학교 산학협력단 송악 추출물을 포함하는 바이오필름 형성 억제용 조성물

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3840527A (en) 1971-08-16 1974-10-08 Riker Laboratories Inc Haloalkylsulfonamido-substituted tolan and stilbene compounds
US5420361A (en) * 1992-02-05 1995-05-30 Bio-Technical Resources Formulation of and dehydration of hydroxylated diphenyl acetylenes
US6599945B2 (en) 2000-08-15 2003-07-29 Northeastern Ohio Universities College Of Medicine Methods for treating subjects infected with a herpes virus
KR101076018B1 (ko) 2003-01-08 2011-10-21 유니버시티 오브 워싱톤 항균제
US8530512B2 (en) * 2004-10-18 2013-09-10 Aaron P. Monte Broad spectrum gram-positive antimicrobials and anthelmintics with efficacy against drug-resistant strains and Mycobacterium species
TWI519508B (zh) * 2007-06-12 2016-02-01 Achaogen Inc 抗菌劑
US8716355B2 (en) * 2007-06-20 2014-05-06 Kent State University Hydroxylated tolans and related compounds in the treatment of a cancer
WO2009126700A1 (en) * 2008-04-08 2009-10-15 Kent State University Hydroxylated tolans and related compounds as cosmetics or therapeutics for skin conditions
IT1399222B1 (it) 2010-01-28 2013-04-11 Pittiruti Catetere per la somministrazione parenterale di fluidi biomedicali
CN101914080B (zh) * 2010-08-05 2012-10-03 上海交通大学 苯并呋喃-3-甲酮取代苯基类化合物及其制备和应用
EP2750625A4 (en) 2011-08-31 2015-08-19 Univ Columbia REDUCTION OF BIOFILMS ON MEDICAL DEVICES
KR20170141705A (ko) * 2015-04-08 2017-12-26 바이오멘딕스, 엘엘씨 상처 치유를 조절하기 위한 제형 및 방법
US11351126B2 (en) * 2017-07-27 2022-06-07 BioMendics, LLC Substituted tolans for the modulation of microbial colonization

Also Published As

Publication number Publication date
US20220296538A1 (en) 2022-09-22
MY204404A (en) 2024-08-27
IL272188B (en) 2022-08-01
AU2018306420B2 (en) 2024-02-15
KR102620652B1 (ko) 2024-01-03
AU2018306420A1 (en) 2020-02-06
EP3658128A1 (en) 2020-06-03
JP7266597B2 (ja) 2023-04-28
BR112020001619A2 (pt) 2020-07-21
US20200206154A1 (en) 2020-07-02
IL272188A (en) 2020-03-31
KR20200087122A (ko) 2020-07-20
MX2020001043A (es) 2020-08-17
WO2019023425A1 (en) 2019-01-31
US11351126B2 (en) 2022-06-07
EP3658128A4 (en) 2021-04-21
JP2020529471A (ja) 2020-10-08
SG11202000708SA (en) 2020-02-27
CN111526873A (zh) 2020-08-11
CA3070427A1 (en) 2019-01-31

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