CN111467420A - 一种治疗甲状腺肿瘤的中药组合物 - Google Patents
一种治疗甲状腺肿瘤的中药组合物 Download PDFInfo
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Abstract
本发明提供了一种治疗甲状腺肿瘤的中药组合物，组分包括：络石藤、黄药子、夏枯草、雷公藤、猫爪草、半夏、地锦草、水红花子、八月札、草河车、半枝莲和川芎。所述治疗甲状腺肿瘤的中药组合物中草河车具有清热解毒，止痉，止痛的功效，并且常被用作抗癌治疗，具有广泛抗癌的作用；所述半枝莲功能为清热解毒、活血化瘀、利水消肿，主治毒蛇咬伤、疔疮疖肿、肝炎、肿瘤等病症，猫爪草具有化痰散结，解毒消肿，用于瘰疬痰核，疔疮、解毒消肿；川芎具有活血行气，祛风止痛，用于血瘀气滞痛证，头痛、风湿痹痛；通过上述中药组合物调理，能够扶正固本，活血化瘀，清热解毒、解散消肿，益气养阴，对甲状腺肿瘤有很好的治疗效果，且无副作用。
Description
技术领域
本发明属于中医中药技术领域，具体涉及一种治疗甲状腺肿瘤的中药组合物。
背景技术
甲状腺肿瘤属于祖国医学中“石瘿”、“肉瘿”、“气瘿”等“瘿瘤”的范畴，甲状腺肿瘤患者的发病多与情志因素密切相关，由于长期情志不舒，忧思郁怒，肝郁化火，灼津成痰，痰气郁热互结于颈部则颈部肿胀；或脾失健运，痰湿内生，随肝火上逆博结于颈部则肿；气病及血，痰浊阻络则气滞痰瘀互结，近年来甲状腺肿瘤的发病率逐渐增高，特别是在内分泌系统肿瘤和头颈部肿瘤中发病率跃居第一位，在人体所有恶性肿瘤中，甲状腺癌所占比例接近1％。甲状腺肿瘤包括甲状腺腺瘤和甲状腺癌，与后者相比，甲状腺腺瘤通常指呈良性生长的瘤性组织，并有完整的包膜包裹。甲状腺良性肿瘤主要包括甲状腺腺瘤、甲状腺囊肿、结节性甲状腺肿，其中结节性甲状腺肿发病率较高，在我国发病率约为4-7％，并且可恶变为甲状腺癌或同时伴发甲状腺癌。甲状腺肿瘤通常发病隐匿，以甲状腺结节表现者居多，不易早期发现，患者可能偶然会触摸到颈部单个或多个、质硬、高低不平、不对称性的肿块，多数并无自觉不适。疾病进展后可因肿物增大压迫临近组织器官，产生一系列的临床症状，从而影响患者生活质量。近年来国内外对甲状腺肿瘤的治疗方法不断更新，主要的治疗有手术、内分泌药物治疗、碘放射治疗及基因治疗等，不仅花费昂贵，且复发率高、副作用明显，其治疗效果并不尽人意，因此，其药物上的改进和创新势在必行。
发明内容
本发明的目的是提供一种治疗甲状腺肿瘤的中药组合物，以达到治疗甲状腺肿瘤，减少副作用的目的。
为实现上述目的，技术方案如下：
一种治疗甲状腺肿瘤的中药组合物，所述组合物的组分包括：络石藤、黄药子、夏枯草、雷公藤、猫爪草、半夏、地锦草、水红花子、八月札、草河车、半枝莲和川芎。
按质量份计，所述组合物的组分包括：络石藤10-18份、黄药子20-35份、夏枯草13-25份、雷公藤15-25份、猫爪草10-16份、半夏15-23份、地锦草10-23份、水红花子15-27份、八月札14-21份、草河车5-13份、半枝莲9-18份和川芎11-17份。
按质量份计，所述组合物的组分包括：络石藤12-16份、黄药子22-31份、夏枯草16-23份、雷公藤17-21份、猫爪草12-15份、半夏16-20份、地锦草13-19份、水红花子17-23份、八月札16-18份、草河车7-11份、半枝莲11-16份和川芎13-16份。
络石藤，味苦，辛，性微寒；归心，肝，肾经；具有通络止痛，凉血清热，解毒消肿的功效，主治风湿痹痛，腰膝酸痛，筋脉拘挛，咽喉肿痛，疔疮肿毒，跌打损伤，外伤出血等症状。
黄药子，味苦、辛，性凉；归肝、胃、心、肺经；具有解毒消肿，化痰散结，凉血止血的功效；主治甲状腺肿大，淋巴结结核，咽喉肿痛，吐血，咯血，百日咳，癌肿，外用治疮疖等。
夏枯草，味辛、苦，性寒；归肝、胆经；具有清热泻火，明目，散结消肿的功效；主治适用于淋巴结核、甲状腺肿、乳痈、头目眩晕、口眼歪斜、筋骨疼痛、肺结核、血崩、带下、急性传染性黄疸型肝炎及细菌性痢疾等。现代药理研究表明，夏枯草有降低血压的作用，并能扩张血管，其所含芦丁有抗炎作用，并能降低血管通透性，减少脆性，降低肝脂。夏枯草还有抵制癌细胞的作用。
雷公藤，味苦、辛，性凉；具有祛风除湿、通络止痛、消肿止痛、解毒杀虫的功效；主治湿热结节、癌瘤积毒，临床上用其治疗麻风反应、类风湿性关节炎等疾病。
猫爪草，味甘辛，性温；归肝，肺经；具有：攻毒杀虫，祛风止痛的功效；主治疮疡肿毒，乳痈，瘰疬，顽癣瘙痒，癌肿；风湿痹痛，牙痛，风疹瘙痒等病症。
半夏，味辛，性温；归脾经、胃经、肺经；具有燥湿化痰、降逆止呕、消痞散结的功效；外用消肿止痛，主治湿痰、寒痰证，呕吐；心下痞，结胸，梅核气；瘿瘤，痰核，痈疽肿毒，毒蛇咬伤等。
地锦草，味辛，性平；归肺经、肝经、胃经、大肠经、膀胱经；具有清热解毒，利湿退黄，活血止血的功效，主治痢疾；泄泻；黄疸；咳血；吐血；尿血；便血；崩漏；乳汁不下；跌打肿痛及热毒疮疡等。
水红花子，味咸，性微寒；归肝、胃经；具有散血消瘕，消积止痛，利水消肿的功效；主治瘕瘕痞块，瘿瘤，食积不消，胃脘胀痔，水肿腹水等疾病。
八月札，味甘，性寒；归肝、脾、肾经；具有舒肝理气，活血，散瘀止痛，除烦利尿的功效；主治肝胃气痛，胃热食呆，烦渴，亦白痢疾，腰痛，胁痛，疝气，绝经，子宫下坠等疾病。
草河车，味苦，性凉；归心经、肝经、肺经、胃经、大肠经；具有败毒抗癌、消肿止痛、清热定惊、镇咳平喘的功效；主治痈肿肺痨久咳、跌打损伤、蛇虫咬伤、淋巴结核、骨髓炎等病症。
半枝莲，味辛，性平；归肺经、肝经、肾经；具有清热解毒、活血化瘀、利尿，消肿止痛，抗癌的功效，主治阑尾炎、肝炎、胃痛、早期肝癌、肺癌、子宫颈癌、乳腺炎等病症。
川芎，味辛，性温；归肝、胆经；具有行气开郁，祛除风燥湿，活血止痛的功效，主治风冷头痛旋晕，胁痛腹疼，寒痹筋挛，经闭，难产，产后瘀阻块痛，痈疽疮疡，还可用于治疗月经不调，经闭痛经，瘕腹痛，胸胁刺痛，跌扑肿痛，头痛，风湿痹痛等病症。
本发明的有益效果是：提供了一种治疗甲状腺肿瘤的中药组合物，所述治疗甲状腺肿瘤的中药组合物中草河车具有清热解毒，止痉，止痛的功效，并且常被用作抗癌治疗，具有广泛抗癌的作用；所述半枝莲功能为清热解毒、活血化瘀、利水消肿，主治毒蛇咬伤、疔疮疖肿、肝炎、肿瘤等病症，猫爪草具有化痰散结，解毒消肿，用于瘰疬痰核，疔疮、解毒消肿；川芎具有活血行气，祛风止痛，用于血瘀气滞痛证，头痛、风湿痹痛；通过本发明所述中药组合物调理，能够扶正固本，活血化瘀，清热解毒、解散消肿，益气养阴，对甲状腺肿瘤有很好的治疗效果，且无副作用。
具体实施方式
以下各步骤仅用以说明本发明的技术方案，而非对其限制；尽管参照前述各步骤对本发明进行了详细的说明，但本领域的普通技术人员应当理解：其依然可以对前述各步骤所记载的技术方案进行修改，或者对其中部分或者全部技术特征进行等同替换；而这些修改或者替换，并不使相应技术方案的本质脱离本发明各步骤技术方案的范围。
实施例1
一种治疗甲状腺肿瘤的中药组合物，所述中药组合物各组分具体的质量份数包括：络石藤12份、黄药子22份、夏枯草16份、雷公藤17份、猫爪草12份、半夏16份、地锦草13份、水红花子17份、八月札16份、草河车7份、半枝莲11份和川芎13份。
实施例2
一种治疗甲状腺肿瘤的中药组合物，所述中药组合物各组分具体的质量份数包括：络石藤16份、黄药子31份、夏枯草23份、雷公藤21份、猫爪草15份、半夏20份、地锦草19份、水红花子23份、八月札18份、草河车11份、半枝莲16份和川芎16份。
实施例3
一种治疗甲状腺肿瘤的中药组合物，所述中药组合物各组分具体的质量份数包括：络石藤14份、黄药子27份、夏枯草21份、雷公藤19份、猫爪草14份、半夏18份、地锦草16份、水红花子20份、八月札17份、草河车9份、半枝莲14份和川芎15份。
实施例4利用本发明治疗良性甲状腺肿瘤的临床效果
诊断标准:
1.颈前区肿物，无或伴有甲亢临床表现；
2.体检显示颈前区肿块随吞咽上下活动；
3.颈部B超提示甲状腺良性肿瘤；
4.甲状腺功能正常或有甲亢表现。
全部观察病例共60例，其中男女各30人，60个病例均患有上述症状的甲状腺肿瘤，其中肿瘤直径分布在1-5cm，平均长度为2.2cm左右，所有观察病例均未经其他方法治疗，然后平均分为3组，分别服用上述实施例1-3中所述的中药组合物，其中服用方法为：分别将上述实施例1-3所述的一种治疗甲状腺肿瘤的中药组合物，按照各组分所添加的质量份数分别放入到药罐中，加水没入，盖上盖子，用文火对药罐中的药液煎制两个小时，熬制成汤剂，每天一服，2个月为一个疗程，连续使用三个疗程后观察疗效。
其中疗效判定为治愈：颈前肿物消失，B超检查甲状腺未见占位；有效：肿物缩小，症状减轻，B超检查缩小1/3-2/3以上；无效：治疗三个疗程后肿物无变化或继续增大，临床症状存在，B超检查无明显变化或逐渐增大。
治疗结果如表1所示，可以看出实施例1、实施例2和实施例3分别对甲状腺肿瘤具有很好的治疗效果，治愈率高达70％，经后续观察无其他副作用且没有复发，因此本发明所述的中药组合物对甲状腺肿瘤具有肿瘤有很好的治疗效果，且无副作用。
表1
| 项目 | 治愈 | 有效 | 无效 |
| 实施例1 | 70％ | 25％ | 5％ |
| 实施例2 | 65％ | 30％ | 5％ |
| 实施例3 | 70％ | 30％ | 0 |
Claims (6)
1.一种治疗甲状腺肿瘤的中药组合物，其特征在于，所述组合物的组分包括：络石藤、黄药子、夏枯草、雷公藤、猫爪草、半夏、地锦草、水红花子、八月札、草河车、半枝莲和川芎。
2.根据权利要求1中所述的治疗甲状腺肿瘤的中药组合物，其特征在于，按质量份计，所述组合物的组分包括：络石藤10-18份、黄药子20-35份、夏枯草13-25份、雷公藤15-25份、猫爪草10-16份、半夏15-23份、地锦草10-23份、水红花子15-27份、八月札14-21份、草河车5-13份、半枝莲9-18份和川芎11-17份。
3.根据权利要求2中所述的治疗甲状腺肿瘤的中药组合物，其特征在于，按质量份计，所述组合物的组分包括：络石藤12-16份、黄药子22-31份、夏枯草16-23份、雷公藤17-21份、猫爪草12-15份、半夏16-20份、地锦草13-19份、水红花子17-23份、八月札16-18份、草河车7-11份、半枝莲11-16份和川芎13-16份。
4.根据权利要求3中所述的治疗甲状腺肿瘤的中药组合物，其特征在于，按质量份计，所述所述组合物的组分包括：络石藤12份、黄药子22份、夏枯草16份、雷公藤17份、猫爪草12份、半夏16份、地锦草13份、水红花子17份、八月札16份、草河车7份、半枝莲11份和川芎13份。
5.根据权利要求3中所述的治疗甲状腺肿瘤的中药组合物，其特征在于，按质量份计，所述所述组合物的组分包括：络石藤16份、黄药子31份、夏枯草23份、雷公藤21份、猫爪草15份、半夏20份、地锦草19份、水红花子23份、八月札18份、草河车11份、半枝莲16份和川芎16份。
6.根据权利要求3中所述的治疗甲状腺肿瘤的中药组合物，其特征在于，按质量份计，所述所述组合物的组分包括：络石藤14份、黄药子27份、夏枯草21份、雷公藤19份、猫爪草14份、半夏18份、地锦草16份、水红花子20份、八月札17份、草河车9份、半枝莲14份和川芎15份。
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103520507A (zh) * | 2013-10-25 | 2014-01-22 | 王小薇 | 一种治疗甲状腺癌的中药组合物 |
| CN104161952A (zh) * | 2014-08-19 | 2014-11-26 | 大连圣弘医药有限公司 | 治疗甲状腺肿瘤的中药组合物及其制备方法 |
| CN104398831A (zh) * | 2014-12-10 | 2015-03-11 | 孙娅萍 | 一种治疗甲状腺癌的中药配方 |
| CN107115494A (zh) * | 2017-04-18 | 2017-09-01 | 吴冬梅 | 香附消瘿汤剂 |
-
2020
- 2020-04-30 CN CN202010364140.2A patent/CN111467420A/zh active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103520507A (zh) * | 2013-10-25 | 2014-01-22 | 王小薇 | 一种治疗甲状腺癌的中药组合物 |
| CN104161952A (zh) * | 2014-08-19 | 2014-11-26 | 大连圣弘医药有限公司 | 治疗甲状腺肿瘤的中药组合物及其制备方法 |
| CN104398831A (zh) * | 2014-12-10 | 2015-03-11 | 孙娅萍 | 一种治疗甲状腺癌的中药配方 |
| CN107115494A (zh) * | 2017-04-18 | 2017-09-01 | 吴冬梅 | 香附消瘿汤剂 |
Non-Patent Citations (2)
| Title |
|---|
| 姜兆俊: "中药治愈甲状腺腺瘤12例报告", 《中国临床医生》 * |
| 李宇宏: "辨证治疗甲状腺肿块180例", 《湖南中医杂志》 * |
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