CN106938031A - 一种甲状腺瘤的治疗药物 - Google Patents

一种甲状腺瘤的治疗药物 Download PDF

Info

Publication number
CN106938031A
CN106938031A CN201710204283.5A CN201710204283A CN106938031A CN 106938031 A CN106938031 A CN 106938031A CN 201710204283 A CN201710204283 A CN 201710204283A CN 106938031 A CN106938031 A CN 106938031A
Authority
CN
China
Prior art keywords
parts
medicine
root
thyroid
thyroid adenoma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201710204283.5A
Other languages
English (en)
Inventor
李先强
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201710204283.5A priority Critical patent/CN106938031A/zh
Publication of CN106938031A publication Critical patent/CN106938031A/zh
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
    • A61K36/195—Strobilanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315—Isatis, e.g. Dyer's woad
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/344—Codonopsis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/748—Oldenlandia or Hedyotis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

本发明公开了一种甲状腺瘤的治疗药物，医药技术领域，解决甲状腺瘤的病理分析和治疗药物问题，其特征是按下面各中药质量份比组合而成：莪术15份、白花蛇舌草15份、海藻10份、菊花20份、桑白皮20份、党参15份、牛膝18份、板兰根15份、冬瓜皮20份、鸡内金15份、连翘15份、生地15份、甘草8份。

Description

一种甲状腺瘤的治疗药物
技术领域
本发明涉及一种甲状腺瘤的治疗药物，特别涉及以中医中药组合治疗的药物，属于医学技术领域。
背景技术
甲状腺肿瘤是头颈部常见的肿瘤，女性多见。症状为颈前正中肿块，随吞咽活动，部分病人还有声音嘶哑和吞咽困难、呼吸困难。甲状腺肿瘤种类多，有良性和恶性，一般来说，单个肿块，生长较快的恶性可能性大，年龄越小的甲状腺肿块恶性可能性大。由于症状明显，患者一般都能及时就诊。
甲状腺是位于人体颈部甲状软骨下方，气管两旁，形状似蝴蝶，犹如盾甲，所以称之为甲状腺。甲状腺分为左右两叶和峡部。左右两叶位于喉下部与器官上部的两侧面。上端自甲状软骨的中点，下端至第6气管软骨环，有时达胸骨上窝或胸骨后。甲状腺有合成、贮存和分泌甲状腺素的功能，其结构单位为滤泡。甲状腺素是一种含碘酪氨酸的有机结合碘，有四碘酪氨酸(T4)和三碘酪氨酸(T3)两种，合成完毕后便与甲状腺球蛋白结合，贮存在甲状腺滤泡中。释放入血的甲状腺素与血清蛋白结合，其中90%为T4，10%为T3。甲状腺素的主要作用是：加快全身细胞利用氧的效能，加速蛋白质、碳水化合物和脂肪的分解，全面增高人体的代谢，增加热量产生；‚促进人体的生长发育，主要在出生后影响脑和长骨。
甲状腺良性肿瘤很常见，在颈部肿块中，甲状腺瘤约占50%。一般无明显症状，当瘤体较大时，会因为压迫气管、食管、神经而导致呼吸困难、吞咽困难、声音嘶哑等症状，当肿瘤合并出血而迅速增大时会产生局部胀痛。因甲状腺良性肿瘤有恶变可能，一部分虽然是良性，但呈“热结节”（即高功能性），所以需要积极治疗。
甲状腺恶性肿瘤中最常见的是甲状腺癌(Thyroid carcinoma)，极少数可有恶性淋巴瘤及转移瘤，甲状腺癌占全身恶性肿瘤的1%。除髓样癌外，绝大部分甲状腺癌起源于滤泡上皮细胞。甲状腺癌的发病率与地区、种族、性别有一定关系。美国的甲状腺癌发病率较高，根据统计，1973-2002年间，美国甲状腺癌的年发生率由十万分之3.6增加到十万分之8.7，大约增加了2.4倍（P<0.001）,而且这种趋势仍然在逐年增长。国内的甲状腺癌发病率较低，据统计，其中男性约0.8-0.9/10 万，女性约2.0-2.2/10万。
由甲状腺腺瘤或多发的胶性结节所致。单个或多个，可与甲状腺肿同时并存或单独出现。腺瘤一般呈圆或椭圆形，质地大多比周围甲状腺组织硬，无压痛。在扫描图上显示摄I功能为正常、增加或减低；甲状腺显像分别为“温结节”“热结节” “冷结节”。甲状腺摄I率可正常或偏高。肿瘤发展缓慢，临床上大多无症状，但是部分病人发生功能亢进症状。
放射性核素治疗(131碘治疗)：对于乳头状癌、滤泡癌，术后应用碘适合于 45岁以上病人、多发性癌灶、局部侵袭性肿瘤及存在远处转移者。主要是破坏甲状腺切除术后残留的甲状腺组织，对高危病例有利于减少复发和死亡率。应用碘治疗目的是：①破坏残留甲状腺内隐匿微小癌；‚易于使用核素检测复发或转移病灶；③术后随访过程中，增加用状腺球蛋白作为肿瘤标记物的价值。
发明内容
以中医学观点分析甲状腺瘤，属于内部阴虚火旺，外入风邪，痰郁气结，治疗应以清热解毒、祛风拔毒、疏肝理气、软坚散结之中药结合服用治疗，必收到明显之疗效。
一种甲状腺瘤的治疗药物是按下面各中药质量份比组合而成：莪术15份、白花蛇舌草15份、海藻10份、菊花20份、桑白皮20份、党参15份、牛膝18份、板兰根15份、冬瓜皮20份、鸡内金15份、连翘15份、生地15份、甘草8份。
下面分析一种甲状腺瘤的治疗药物中各中药的药性功效。中药莪术破血行气、消积止痛、 散结、破血祛瘀 、行气止痛。白花蛇舍草的功效: 清热解毒, 活血利尿；用于扁桃体炎、咽喉炎、尿路感染、盆腔炎、阑尾炎、肝炎、菌痢、毒蛇咬伤、肿瘤。海藻能抑制肿瘤、 保健、增强免疫力、抗癌、抗肿瘤、抗凝血、 减肥、防止血栓形成。菊花清热解毒、清肝明目、降血压、消除癌细胞、扩张冠状动脉和抑菌的作用，长期饮用能增加人体钙质、调节心肌功能、降低胆固醇，适合中老年人和预防流行性结膜炎时饮用。桑白皮为桑科植物桑的根皮，属于清热祛邪之良药，功效: 泻肺平喘, 利水消肿；用于肺热咳喘, 面目浮肿, 小便不利等症。党参的主要功效是补中益气，功能补脾益肺，适用于各种气虚不足者，四肢无力，食欲不振，大便稀溏，也宜使用党参。牛膝功效: 逐瘀通经, 补肝肾, 强筋骨, 利尿通淋, 引血下行；牛膝是少有的既补兼散的中药，主治: 腰膝酸痛、肾虚亏损。板兰根清热解毒，凉血利咽；用于肺胃热盛所致的咽喉肿痛、口咽干燥，能预防感冒、保健、清热解毒 、凉血、 去火、增强免疫力。冬瓜皮也是清热解毒功效很好的药食两用食品，冬瓜皮有清肝热、抗病毒、消炎消肿功效，并且冬瓜皮口感清香。鸡内金能健脾开胃，消食化积，用于脾胃不和引起的食积胀满，饮食停滞，鸡内金散瘀化结之功效特强，不但用于肾结石，对人体内其它部位的结聚性肿结也有很强的散结化解之功效，但鸡内金温性，需配合清热之中药使用。连翘清热，解毒，散结，消肿；治温热，丹毒，斑疹，痈疡肿毒，瘰疬。生地清肝热、清凉血液，养阴生津。甘草是一种补益中草药；它主治清热解毒，祛痰止咳、脘腹等症状，有补脾益气，健脾胃之功效，调和诸药缓解毒性之功效。
一种肺泡蛋白沉着症的治疗药物发明的有益效果是：发明人以中医学观点分析肺泡蛋白沉着症，属于内部阴虚火旺，外入邪毒，热毒蕴结、胸中大气下陷、瘀血阻络、痰浊不化，治疗应以清热解毒、祛风拔毒、补益肺气、逐瘀化痰的中药结合服用治疗，收到明显之治疗效果。
具体实施方式
一种肺泡蛋白沉着症的治疗药物是按下面各中药质量份比组合而成：菊花20份、桑白皮20份、党参15份、牛膝18份、板兰根15份、冬瓜皮20份、鸡内金15份、白花蛇舌草15份、连翘15份、生地15份、海藻10份、甘草8份。根据上述药物份量比例，一种肺泡蛋白沉着症的治疗药物适合于一个患者服用的一个剂量药量是按下面各中药质量组合而成：菊花20克、桑白皮20克、党参15克、牛膝18克、板兰根15克、冬瓜皮20克、鸡内金15克、白花蛇舌草15克、连翘15克、生地15克、海藻10克、甘草8克。使用方法：与适量的清水煎汤内服药汤，重症者日服一剂量，连服一星期基本消除症状，一星期后可两天服用一剂量，继续服用两个星期以上巩固疗效。

Claims (1)

1.一种甲状腺瘤的治疗药物，其特征是按下面各中药质量份比组合而成：莪术15份、白花蛇舌草15份、海藻10份、菊花20份、桑白皮20份、党参15份、牛膝18份、板兰根15份、冬瓜皮20份、鸡内金15份、连翘15份、生地15份、甘草8份。
CN201710204283.5A 2017-03-30 2017-03-30 一种甲状腺瘤的治疗药物 Withdrawn CN106938031A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710204283.5A CN106938031A (zh) 2017-03-30 2017-03-30 一种甲状腺瘤的治疗药物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710204283.5A CN106938031A (zh) 2017-03-30 2017-03-30 一种甲状腺瘤的治疗药物

Publications (1)

Publication Number Publication Date
CN106938031A true CN106938031A (zh) 2017-07-11

Family

ID=59463519

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710204283.5A Withdrawn CN106938031A (zh) 2017-03-30 2017-03-30 一种甲状腺瘤的治疗药物

Country Status (1)

Country Link
CN (1) CN106938031A (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109541239A (zh) * 2018-12-21 2019-03-29 云南农业大学 一种基于甲状旁腺素血液生化标记选育武定鸡的方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101152538A (zh) * 2007-09-15 2008-04-02 尹克华 治疗甲状腺瘤的中药
CN101537113A (zh) * 2008-03-21 2009-09-23 北京汉潮联创中药科技有限公司 一种治疗甲状腺瘤的中药制剂
CN102357229A (zh) * 2011-11-01 2012-02-22 朱有信 治疗甲状腺瘤的中药
CN103977181A (zh) * 2014-06-01 2014-08-13 李玉丽 一种治疗甲状腺瘤的药物及制备方法
CN105169011A (zh) * 2015-08-31 2015-12-23 秦冬妹 一种治疗甲状腺瘤的药物
CN105287901A (zh) * 2015-11-27 2016-02-03 黄德禄 一种治疗甲状腺瘤的中药丸
CN106109917A (zh) * 2016-08-05 2016-11-16 牟清海 一种治疗甲状腺瘤的外用理疗液

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101152538A (zh) * 2007-09-15 2008-04-02 尹克华 治疗甲状腺瘤的中药
CN101537113A (zh) * 2008-03-21 2009-09-23 北京汉潮联创中药科技有限公司 一种治疗甲状腺瘤的中药制剂
CN102357229A (zh) * 2011-11-01 2012-02-22 朱有信 治疗甲状腺瘤的中药
CN103977181A (zh) * 2014-06-01 2014-08-13 李玉丽 一种治疗甲状腺瘤的药物及制备方法
CN105169011A (zh) * 2015-08-31 2015-12-23 秦冬妹 一种治疗甲状腺瘤的药物
CN105287901A (zh) * 2015-11-27 2016-02-03 黄德禄 一种治疗甲状腺瘤的中药丸
CN106109917A (zh) * 2016-08-05 2016-11-16 牟清海 一种治疗甲状腺瘤的外用理疗液

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109541239A (zh) * 2018-12-21 2019-03-29 云南农业大学 一种基于甲状旁腺素血液生化标记选育武定鸡的方法

Similar Documents

Publication Publication Date Title
CN102824445B (zh) 一种治疗十二指肠溃疡的中药组合物
CN103520670A (zh) 治疗新生儿黄疸的中药组合物
CN111097030A (zh) 一种治疗肿瘤及缓解肿瘤疼痛的中药组合及制备方法
CN106938031A (zh) 一种甲状腺瘤的治疗药物
CN108686121A (zh) 一种治疗肿瘤的中药组合物
CN104162093A (zh) 治疗乳腺癌的中药制剂及其制备方法
CN103520656A (zh) 一种治疗胰腺癌的中药组合物
CN103432269A (zh) 一种治疗放射性肠炎的中药制剂
CN104825817B (zh) 一种具有抗肿瘤作用的中药制剂
CN103520506A (zh) 一种治疗乳腺癌的中药组合物
CN102895392B (zh) 一种治疗十二指肠溃疡的中药
CN102688451B (zh) 一种治疗酒精性脂肪肝的中药组合物
CN105233208A (zh) 一种治疗心力衰竭的中药制剂
CN103877397B (zh) 一种治疗放射性肺损伤的药物及制备方法
CN104083708A (zh) 治疗肩周炎的中药软膏
CN104524535B (zh) 一种治疗慢性肺源性心脏病的中药组合物及其制备方法
CN103893348B (zh) 一种治疗放射性皮肤损伤的中药药膏及制备方法
CN104721740A (zh) 一种治疗淋巴结核、淋巴瘤的中药组合物
CN104800693B (zh) 一种治疗肺癌的中药组合物
CN104758620A (zh) 胆囊炎患者疏肝利胆剂及制备方法
CN104606391A (zh) 一种治疗十二指肠溃疡的中药组合物
CN104043026A (zh) 一种用于治疗胃溃疡、减少药物依赖的药物组合物
CN115282247A (zh) 一种用于治疗癌症晚期的中药及其制备方法
CN113925947A (zh) 一种治疗肝癌的中药配方
CN112370519A (zh) 一种治疗癌症的组合物、制备方法及其应用

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20170711