CN111437326A - Traditional Chinese medicine composition for avoiding plague and preventing infection and external preparation and application thereof - Google Patents

Traditional Chinese medicine composition for avoiding plague and preventing infection and external preparation and application thereof Download PDF

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CN111437326A
CN111437326A CN202010466882.6A CN202010466882A CN111437326A CN 111437326 A CN111437326 A CN 111437326A CN 202010466882 A CN202010466882 A CN 202010466882A CN 111437326 A CN111437326 A CN 111437326A
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chinese medicine
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程亚伟
丁一
陈磊
李景君
林尤海
程亚博
袁冬梅
王珊
颜芬
杨媛
王紫薇
李丽
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Chinese Medicine Hospital Of Hainan Province
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Abstract

The invention provides a traditional Chinese medicine composition for avoiding plague and preventing influenza, an external preparation and application thereof, wherein the active components of the traditional Chinese medicine composition comprise a mixed traditional Chinese medicine A and a mixed traditional Chinese medicine B, and the mixed traditional Chinese medicine A comprises the following raw material medicines in parts by weight: 8-12 parts of angelica dahurica, 8-12 parts of rhizoma acori graminei, 8-15 parts of ageratum and 8-15 parts of folium artemisiae argyi; the mixed traditional Chinese medicine B comprises the following raw material medicines in parts by weight: 8-12 parts of rhizoma atractylodis, 5-12 parts of clove and 5-12 parts of fructus evodiae; the weight ratio of the mixed traditional Chinese medicine A to the mixed traditional Chinese medicine B is 2-5: 1. in the formula, the folium artemisiae argyi and the agastache rugosus are fragrant and avoid dirt and are monarch drugs together, the radix angelicae, the rhizoma atractylodis and the rhizoma acori graminei are fragrant and activate spleen and resolve dampness and are ministerial drugs together, the clove and the fructus evodiae are pungent in flavor, warm in nature and open orifices and are fragrant and harmonized stomach, and are adjuvant drugs together, so that the effects of fragrant and avoiding dirt and resolving turbidity, activating spleen and resolving dampness and harmonizing stomach are achieved together, and the effects of avoiding plague and.

Description

Traditional Chinese medicine composition for avoiding plague and preventing infection and external preparation and application thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for avoiding plague and preventing influenza, and an external preparation and application thereof.
Background
Common cold is a common cold which is a common cold disease with the main clinical manifestations of lung-defense dysfunction, nasal obstruction, watery nasal discharge, sneezing, headache, aversion to cold, fever, general malaise, etc. caused by wind-evil or virus running in time. The temperature changes greatly when seasons change, and cold is easy to catch cold. The traditional Chinese medicine sachet can be absorbed through respiratory tract or skin to play the role of preventing and treating diseases. The traditional Chinese medicine sachet can be worn on person, and can also be placed in a pocket, a car, indoors, a pillow edge and the like, thereby being very convenient. However, the traditional Chinese medicine sachet has poor effect of avoiding plague and preventing influenza, and the traditional Chinese medicine composition prepared by the invention can obviously reduce the times of cold.
Disclosure of Invention
In view of the above, the invention provides a traditional Chinese medicine composition for avoiding plague and preventing influenza, and an external preparation and application thereof.
The technical scheme of the invention is realized as follows: a Chinese medicinal composition for preventing pestilence and influenza comprises mixed Chinese medicinal materials A and B,
the mixed traditional Chinese medicine A comprises the following raw material medicines in parts by weight: 8-12 parts of angelica dahurica, 8-12 parts of rhizoma acori graminei, 8-15 parts of ageratum and 8-15 parts of folium artemisiae argyi;
the mixed traditional Chinese medicine B comprises the following raw material medicines in parts by weight: 8-12 parts of rhizoma atractylodis, 5-12 parts of clove and 5-12 parts of fructus evodiae;
the weight ratio of the mixed traditional Chinese medicine A to the mixed traditional Chinese medicine B is 2-5: 1.
preferably, the mixed traditional Chinese medicine A also contains the following raw material medicines in parts by weight: 8-12 parts of mint, 8-12 parts of eupatorium and 8-12 parts of purple perilla.
Preferably, the weight ratio of the mixed traditional Chinese medicine A to the mixed traditional Chinese medicine B is 2: 1.
a traditional Chinese medicine composition external preparation for avoiding plague and preventing influenza comprises any one of the traditional Chinese medicine compositions for avoiding plague and preventing influenza.
Preferably, the external preparation of the traditional Chinese medicine composition is one of sachet and pill.
The application of the traditional Chinese medicine composition in preparing the medicines for avoiding plague and preventing infection is provided.
Compared with the prior art, the invention has the beneficial effects that:
in the formula, the folium artemisiae argyi and the agastache rugosus are fragrant and avoid dirt and are monarch drugs together, the radix angelicae, the rhizoma atractylodis and the rhizoma acori graminei are fragrant and activate spleen and resolve dampness and are ministerial drugs together, the clove and the fructus evodiae are pungent in flavor, warm in nature and open orifices and are fragrant and harmonized stomach, and are adjuvant drugs together, so that the effects of fragrant and avoiding dirt and resolving turbidity, activating spleen and resolving dampness and harmonizing stomach are achieved together, and the effects of avoiding plague and. The traditional Chinese medicine composition has the advantages that the angelica dahurica, the acorus gramineus, the agastache rugosus and the folium artemisiae argyi are used together to achieve the effects of aromatic defense against dirt and eliminating evil, the rhizoma atractylodis, the clove and the fructus evodiae are used together to achieve the effects of aromatic spleen activating and dampness resolving, and the two groups of traditional Chinese medicines are scientifically matched, so that the traditional Chinese medicine composition is high in cold prevention effect. In addition, the mint, the eupatorium and the perilla are also added as adjuvant drugs, so that the effects of enhancing the fragrance and activating the spleen and enhancing the effects of avoiding plague and preventing infection are enhanced.
Detailed Description
In order to better understand the technical content of the invention, specific examples are provided below to further illustrate the invention.
The experimental methods used in the examples of the present invention are all conventional methods unless otherwise specified.
The materials, reagents and the like used in the examples of the present invention can be obtained commercially without specific description.
The basic conditions of the main raw material drugs are described in the Chinese pharmacopoeia, the Chinese dictionary and the Chinese herbal medicine.
Radix angelicae: [ PROPERTIES AND FLAVOUR ] pungent and warm. [ GUIJING ] enters stomach, large intestine and lung meridians. [ FUNCTIONS ] can dispel wind, remove dampness, relieve pain, relieve swelling, and expel pus. Can be used for treating common cold, headache, supraorbital bone pain, nasal obstruction, nasosinusitis, toothache, leucorrhea, and pyocutaneous disease with swelling and pain.
Rhizoma Acori Graminei (character and taste) is pungent, bitter and slightly warm. [ GUIJING ] can be attributed to heart, liver and spleen meridians. [ FUNCTIONS ] can resolve phlegm, induce resuscitation, remove dampness, promote the circulation of qi, dispel wind, relieve arthralgia, dissipate stagnation and alleviate pain. Can be used for treating fever unconsciousness, phlegm syncope, abdominal distention and pain, rheumatalgia, phlegm obstruction of heart, improving blood rheological property, resisting thrombosis, and resisting myocardial ischemia.
Mint: [ PROPERTIES AND FLAVOUR ] pungent and cool. [ GUIJING ] enters lung and liver meridians. [ FUNCTIONS ] can disperse wind-heat. Clear head and eyes, promote eruption. Can be used for treating wind-heat type common cold, headache, conjunctival congestion, pharyngitis, aphtha, rubella, measles, and chest and hypochondrium swelling.
And (3) ageratum: [ PROPERTIES AND FLAVOUR ] pungent and slightly warm. [ GUIJING ] enters lung, spleen and stomach meridians. [ FUNCTIONS ] can promote the flow of qi, regulate the middle warmer, remove dirt, and eliminate dampness. It is used to treat common cold with summer-heat and dampness, cold and heat, headache, fullness and distention in chest and abdomen, emesis, diarrhea, malaria, dysentery, and halitosis.
Herba Eupatorii: [ PROPERTIES AND FLAVOUR ] pungent and mild. [ GUIJING ] can enter spleen, stomach and lung meridians. [ FUNCTIONS ] can dispel dampness with aromatics, activate the spleen, stimulate the appetite, relieve exterior syndrome and relieve summer-heat. Can be used for treating damp stagnation, gastric fullness, emesis, halitosis, sialorrhea, summer-heat dampness, headache, and chest distress.
Purple perilla: [ PROPERTIES AND FLAVOUR ] pungent and warm. [ GUIJING ] enters lung and spleen meridians. [ FUNCTIONS ] can dispel cold, relieve exterior syndrome, regulate qi, and strengthen the middle warmer. Can be used for treating wind-cold type common cold, headache, cough, and fullness and distention of chest and abdomen.
Folium artemisiae argyi: [ PROPERTIES AND WESTERN PROPERTIES ] is pungent, bitter and warm; has little toxicity. [ GUIJING ] enters liver, spleen and kidney meridians. [ FUNCTIONS ] can dispel cold, alleviate pain, warm meridians and stop bleeding. Can be used for treating lower abdomen psychroalgia, irregular menstruation, infertility due to cold womb, hematemesis, epistaxis, metrorrhagia, metrostaxis, and pregnancy bleeding; it can be used for treating skin pruritus. Vinegar moxa charcoal warms the channels to stop bleeding. Can be used for treating hemorrhage due to deficiency cold.
Rhizoma atractylodis: [ PROPERTIES AND WESTERN ] is pungent, bitter and warm. [ GUIJING ] can enter spleen, stomach and liver meridians. [ FUNCTIONS ] can eliminate dampness, invigorate spleen, dispel wind, dispel cold, and improve eyesight. Can be used for treating abdominal distention, diarrhea, edema, tinea pedis, paralysis 36484m, rheumatalgia, common cold due to wind-cold evil, and night blindness.
Clove: [ PROPERTIES AND FLAVOUR ] pungent and warm. [ GUIJING ] can enter spleen, stomach, lung and kidney meridians. [ FUNCTIONS ] can warm the middle-jiao, check adverse rise of qi, tonify kidney, and strengthen yang. Can be used for treating deficiency-cold of spleen and stomach, singultus emesis, anorexia vomiting and diarrhea, psychroalgia of heart and abdomen, and sexual impotence due to kidney deficiency.
Evodia fruit: [ PROPERTIES AND FLAVOUR ] pungent, bitter and hot; has little toxicity. [ GUIJING ] enters liver, spleen, stomach and kidney meridians. [ FUNCTIONS ] can dispel cold, alleviate pain, check adverse rise of qi, arrest vomiting, strengthen yang and arrest diarrhea. Can be used for treating syncope headache, cold hernia abdominal pain, cold dampness loempe, menstrual abdominal pain, emesis, acid regurgitation, morning diarrhea, and aphtha; hypertension is caused.
Example 1
A Chinese medicinal composition for preventing pestilence and influenza comprises mixed Chinese medicinal materials A and B,
the mixed traditional Chinese medicine A is prepared from the following raw material medicines in parts by weight: 8 parts of angelica dahurica, 12 parts of rhizoma acori graminei, 8 parts of ageratum and 15 parts of folium artemisiae argyi;
the mixed traditional Chinese medicine B is prepared from the following raw material medicines in parts by weight: 8 parts of rhizoma atractylodis, 12 parts of clove and 5 parts of fructus evodiae;
the weight ratio of the mixed traditional Chinese medicine A to the mixed traditional Chinese medicine B is 2: 1.
according to the weight parts, the raw material medicines are crushed and then put into a sachet medicine bag to prepare the traditional Chinese medicine sachet.
Example 2
A Chinese medicinal composition for preventing pestilence and influenza comprises mixed Chinese medicinal materials A and B,
the mixed traditional Chinese medicine A is prepared from the following raw material medicines in parts by weight: 12 parts of angelica dahurica, 8 parts of rhizoma acori graminei, 15 parts of ageratum and 8 parts of folium artemisiae argyi;
the mixed traditional Chinese medicine B is prepared from the following raw material medicines in parts by weight: 12 parts of rhizoma atractylodis, 5 parts of clove and 12 parts of fructus evodiae;
the weight ratio of the mixed traditional Chinese medicine A to the mixed traditional Chinese medicine B is 5: 1.
and (3) crushing the raw materials according to the weight parts, and then filling into a sachet medicinal bag to obtain the traditional Chinese medicine sachet.
Example 3
A Chinese medicinal composition for preventing pestilence and influenza comprises mixed Chinese medicinal materials A and B,
the mixed traditional Chinese medicine A is prepared from the following raw material medicines in parts by weight: 10 parts of angelica dahurica, 10 parts of rhizoma acori graminei, 10 parts of ageratum and 10 parts of folium artemisiae argyi;
the mixed traditional Chinese medicine B is prepared from the following raw material medicines in parts by weight: 10 parts of rhizoma atractylodis, 10 parts of clove and 10 parts of fructus evodiae;
the weight ratio of the mixed traditional Chinese medicine A to the mixed traditional Chinese medicine B is 2: 1.
and (3) crushing the raw materials according to the weight parts, and then filling into a sachet medicinal bag to obtain the traditional Chinese medicine sachet.
Example 4
The difference between the embodiment and embodiment 3 is that the mixed traditional Chinese medicine A also contains the following raw material medicines: mint, eupatorium and perilla.
A Chinese medicinal composition for preventing pestilence and influenza comprises mixed Chinese medicinal materials A and B,
the mixed traditional Chinese medicine A is prepared from the following raw material medicines in parts by weight: 10 parts of angelica dahurica, 10 parts of grassleaf sweelflag rhizome, 10 parts of mint, 10 parts of ageratum, 10 parts of fortune eupatorium herb, 10 parts of purple perilla and 10 parts of Chinese mugwort leaf;
the mixed traditional Chinese medicine B is prepared from the following raw material medicines in parts by weight: 10 parts of rhizoma atractylodis, 10 parts of clove and 10 parts of fructus evodiae;
the weight ratio of the mixed traditional Chinese medicine A to the mixed traditional Chinese medicine B is 2: 1.
and (3) crushing the raw materials according to the weight parts, and then filling into a sachet medicinal bag to obtain the traditional Chinese medicine sachet.
Comparative example 1
The difference between the comparative example and the example 3 is that the agastache rugosus is replaced by the same amount of storax, the rhizoma acori graminei is replaced by the same amount of radix curcumae, and the fructus evodiae is replaced by the same amount of pepper.
Storax: [ PROPERTIES AND FLAVOUR ] pungent and warm. Meridian tropism [ meridian tropism ] meridian tropism is heart and spleen meridian tropism. [ FUNCTIONS ] can be used for treating theft, removing filth, and relieving pain. Can be used for treating apoplexy, phlegm syncope, sudden syncope, chest and abdomen psychroalgia, and epilepsy.
Turmeric root-tuber: [ PROPERTIES AND WESTERPHIES ] is pungent, bitter and cold in nature. [ GUIJING ] enters liver, heart and lung meridians. [ FUNCTIONS ] can promote the circulation of qi, dispel blood stasis, clear away the heart-fire, relieve depression, promote the function of gallbladder, and relieve jaundice. Can be used for treating amenorrhea, dysmenorrhea, chest and abdomen distention and pain, pricking pain, fever unconsciousness, epilepsy, jaundice, and dark urine.
Chinese prickly ash: [ CHARACTERISTIC FLAVOR ] is pungent and warm in nature. [ GUIJING ] pertains to the spleen, stomach and kidney meridians. [ FUNCTIONS ] can warm the middle energizer to relieve pain, kill parasites to relieve itching. Can be used for treating abdominal psychroalgia, emesis, diarrhea, abdominal pain due to parasitic infestation, and ascariasis; it can be used for treating eczema and pruritus.
Comparative example 2
The difference between the comparative example and the example 3 is that the weight ratio of the mixed traditional Chinese medicine A to the mixed traditional Chinese medicine B is 0.1: 1.
comparative example 3
The difference between the comparative example and the example 3 is that the weight ratio of the mixed traditional Chinese medicine A to the mixed traditional Chinese medicine B is 10: 1.
the traditional Chinese medicine sachet prepared by the method is applied to clinic:
1. more than 10 cases of cold in the last year are collected, and 320 cases of repeated cold patients are collected, wherein the age is 6-40 years old. The collected cases meet the diagnosis standard of traditional Chinese medicine syndrome, refer to "internal medicine of traditional Chinese medicine" for treating cold ", and simultaneously meet the diagnosis standard of common cold of" practical internal medicine "of western medicine. The test groups are randomly grouped, namely the test group 1 to the test group 8, and 40 cases are formed in each group. The gender distribution, mean age for each group are shown in the following table:
Figure BDA0002512956010000061
the patients in each group have no statistical difference in age, sex and the like and are comparable.
2. The application method and the treatment course are as follows: the traditional Chinese medicine sachets of examples 1-4 and comparative examples 1-3 and the control group (main traditional Chinese medicine components: radix angelicae, rhizoma atractylodis, fructus evodiae, herba agastaches, calamus, fructus tsaoko, borneol and the like) are respectively used in the test group 1-8 correspondingly, and each sachet bag contains about 25 g of traditional Chinese medicine. Each person wears 1 sachet per day, smells before nose for 3-4 times every day, each time for 2-3 minutes, and puts on the edge of pillow when sleeping. The sachet was changed 1 time every 10 days and was used continuously for 3 months.
3. Criteria for judging therapeutic effects
The effect is shown: during the use of the sachet, there was no cold.
The method has the following advantages: during the use of the sachet, the number of cold is reduced by more than 50%, and the cold symptoms are alleviated.
And (4) invalidation: the cold frequency is not reduced, and the cold symptoms are not improved.
4. Therapeutic results
Figure BDA0002512956010000062
The clinical conditions show that the traditional Chinese medicine sachet disclosed by the embodiment 1-4 of the invention has an obvious effect on preventing cold, the significant efficiency is more than 72.5%, and the total effective rate is more than 97.5%.
5. Typical cases
Medical record 1: wangzhi, male, 11 years old, Pinsu is susceptible to cold, if there is cold in the relatives around, Wangzhi will also have cold after contacting with it, the cold is more than 10 times in the last year, for the traditional Chinese medicine sachet in the embodiment 3 of the invention to carry with, smell 3-4 times before the nose every day, each time 2-3 minutes, put on the edge of the pillow when sleeping; the sachet was periodically replaced every 10 days and was continuously used for 3 months. During the use period of the sachet, Wangzhi has no cold.
Medical record 2: liu Yi, male, 35 years old, Pinsu physique deviation, susceptibility to cold, cold more than 10 times in the last year, the traditional Chinese medicine sachet of embodiment 4 of the invention is carried with, smells 3-4 times before the nose every day, each time for 2-3 minutes, and is placed on the edge of the pillow when sleeping; the sachets were replaced periodically every 10 days. In winter, all 4 people working in the same office with Liu get influenza, but Liu never gets influenza. During the use of the sachet, Liu somebody has no cold.
6. And (4) adverse reaction observation: in the treatment observation cases, no adverse reaction is found.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (6)

1. A Chinese medicinal composition for preventing pestilence and influenza is characterized in that its active ingredients comprise mixed Chinese medicine A and mixed Chinese medicine B,
the mixed traditional Chinese medicine A comprises the following raw material medicines in parts by weight: 8-12 parts of angelica dahurica, 8-12 parts of rhizoma acori graminei, 8-15 parts of ageratum and 8-15 parts of folium artemisiae argyi;
the mixed traditional Chinese medicine B comprises the following raw material medicines in parts by weight: 8-12 parts of rhizoma atractylodis, 5-12 parts of clove and 5-12 parts of fructus evodiae;
the weight ratio of the mixed traditional Chinese medicine A to the mixed traditional Chinese medicine B is 2-5: 1.
2. the traditional Chinese medicine composition for avoiding plague and preventing influenza according to claim 1, wherein the mixed traditional Chinese medicine A further comprises the following raw material medicines in parts by weight: 8-12 parts of mint, 8-12 parts of eupatorium and 8-12 parts of purple perilla.
3. The traditional Chinese medicine composition for avoiding plague and preventing influenza according to claim 1 or 2, wherein the weight ratio of the mixed traditional Chinese medicine A to the mixed traditional Chinese medicine B is 2: 1.
4. a Chinese medicinal composition external preparation for preventing and treating pestilence and cold, which is characterized by comprising the Chinese medicinal composition for preventing and treating pestilence and cold of any one of claims 1 to 3.
5. The external preparation of a Chinese medicinal composition for preventing and treating pestilence and influenza according to claim 4, wherein the external preparation of a Chinese medicinal composition is one of sachet and pill.
6. Use of the Chinese medicinal composition of any one of claims 1 to 3 in the preparation of a medicament for preventing pestilence and cold.
CN202010466882.6A 2020-05-28 2020-05-28 Traditional Chinese medicine composition for avoiding plague and preventing infection and external preparation and application thereof Pending CN111437326A (en)

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