CN111419845A - 应用控制食欲不振的化合物的组合物和方法 - Google Patents

应用控制食欲不振的化合物的组合物和方法 Download PDF

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Publication number
CN111419845A
CN111419845A CN202010001164.1A CN202010001164A CN111419845A CN 111419845 A CN111419845 A CN 111419845A CN 202010001164 A CN202010001164 A CN 202010001164A CN 111419845 A CN111419845 A CN 111419845A
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China
Prior art keywords
carmorelin
composition
day
serum
animals
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Pending
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CN202010001164.1A
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English (en)
Chinese (zh)
Inventor
B·佐勒斯
L·罗兹
E·海宁
G·德瓦拉杰
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Aratana Therapeutics Inc
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Aratana Therapeutics Inc
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Publication of CN111419845A publication Critical patent/CN111419845A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/111Aromatic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • A23K20/132Heterocyclic compounds containing only one nitrogen as hetero atom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • A23K20/137Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/10Feeding-stuffs specially adapted for particular animals for ruminants
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/20Feeding-stuffs specially adapted for particular animals for horses
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/40Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Feed For Specific Animals (AREA)
  • Dermatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN202010001164.1A 2012-09-27 2013-09-27 应用控制食欲不振的化合物的组合物和方法 Pending CN111419845A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261706164P 2012-09-27 2012-09-27
US61/706,164 2012-09-27
CN201380061931.6A CN105072909A (zh) 2012-09-27 2013-09-27 应用控制食欲不振的化合物的组合物和方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201380061931.6A Division CN105072909A (zh) 2012-09-27 2013-09-27 应用控制食欲不振的化合物的组合物和方法

Publications (1)

Publication Number Publication Date
CN111419845A true CN111419845A (zh) 2020-07-17

Family

ID=50339468

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202010001164.1A Pending CN111419845A (zh) 2012-09-27 2013-09-27 应用控制食欲不振的化合物的组合物和方法
CN201380061931.6A Pending CN105072909A (zh) 2012-09-27 2013-09-27 应用控制食欲不振的化合物的组合物和方法

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CN201380061931.6A Pending CN105072909A (zh) 2012-09-27 2013-09-27 应用控制食欲不振的化合物的组合物和方法

Country Status (18)

Country Link
US (1) US11090292B2 (enExample)
EP (3) EP2906041A4 (enExample)
JP (2) JP6779618B2 (enExample)
KR (6) KR20230097201A (enExample)
CN (2) CN111419845A (enExample)
AR (2) AR092713A1 (enExample)
AU (2) AU2013323349B2 (enExample)
BR (1) BR112015006282B1 (enExample)
CA (1) CA2886091C (enExample)
DK (1) DK3524260T3 (enExample)
ES (1) ES2959427T3 (enExample)
MX (2) MX2015003564A (enExample)
NZ (2) NZ746394A (enExample)
PL (1) PL3524260T3 (enExample)
PT (1) PT3524260T (enExample)
RU (1) RU2648958C2 (enExample)
TW (3) TWI667024B (enExample)
WO (1) WO2014052780A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2011105611A1 (ja) 2010-02-26 2013-06-20 ラクオリア創薬株式会社 悪液質を治療するためのグレリン受容体作動物質
US10039813B2 (en) 2012-02-07 2018-08-07 Massachusetts Institute Of Technology Use of antagonists of ghrelin or ghrelin receptor to prevent or treat stress-sensitive psychiatric illness
PL3524260T3 (pl) 2012-09-27 2023-11-27 Elanco Animal Health Incorporated Kompozycje farmaceutyczne do leczenia braku apetytu
US9724396B2 (en) 2013-03-15 2017-08-08 Massachusetts Institute Of Technology Use of antagonists of growth hormone or growth hormone receptor to prevent or treat stress-sensitive psychiatric illness
BR112017016078A2 (pt) * 2015-01-28 2018-04-03 Aratana Therapeutics Inc composições e métodos para uso crônico de um composto de ganho de peso
WO2016138099A1 (en) 2015-02-24 2016-09-01 Massachusetts Institute Of Technology Use of ghrelin or functional ghrelin receptor agonists to prevent and treat stress-sensitive psychiatric illness
MX388206B (es) * 2016-11-11 2025-03-19 Hills Pet Nutrition Inc Composiciones y métodos de alimento para mascotas.

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CA2095786A1 (en) 1992-05-08 1993-11-09 Franco J. Vaccarino Method of stimulating appetite
TW432073B (en) 1995-12-28 2001-05-01 Pfizer Pyrazolopyridine compounds
EP1159964B1 (en) 2000-05-31 2009-10-28 Pfizer Products Inc. Use of growth hormone secretagogues for stimulating gastrointestinal motility
EP1181933A3 (en) 2000-06-29 2002-04-10 Pfizer Products Inc. Use of growth hormone secretagogues for stimulating or increasing appetite
US8309603B2 (en) * 2004-06-07 2012-11-13 University Of Tennessee Research Foundation SARMs and method of use thereof
US7476653B2 (en) 2003-06-18 2009-01-13 Tranzyme Pharma, Inc. Macrocyclic modulators of the ghrelin receptor
US7491695B2 (en) * 2003-06-18 2009-02-17 Tranzyme Pharma Inc. Methods of using macrocyclic modulators of the ghrelin receptor
WO2005097173A2 (en) * 2004-04-07 2005-10-20 Gastrotech Pharma A/S Use of ghrelin for the treatment of hyperthyroidism
WO2006045313A2 (en) * 2004-10-27 2006-05-04 Gastrotech Pharma A/S Uses of secretagogues for treatment of organ transplant patients
JP2009514824A (ja) * 2005-11-02 2009-04-09 ネステク ソシエテ アノニム 雄の哺乳動物における体脂肪の蓄積を低減するためのイソフラボン組成物及びその使用方法
JP5325092B2 (ja) * 2006-03-13 2013-10-23 リアット・ミンツ 悪液質および/または食欲不振症および/または食欲不振症−悪液質および/または栄養失調および/または脂肪異栄養症および/または筋肉消耗および/または食欲−刺激を治療するためのグレリンスプライス変異体の使用
NZ576470A (en) 2006-09-27 2012-09-28 Ipsen Pharma Sas Analogs of ghrelin substituted at the n-terminal
JP2008127377A (ja) * 2006-11-24 2008-06-05 Jichi Medical Univ Ghs−r作動薬を含有してなるメタボリックシンドローム又は高血圧症の予防・治療剤。
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Publication number Publication date
EP2906041A2 (en) 2015-08-19
EP3524260B1 (en) 2023-09-13
CA2886091A1 (en) 2014-04-03
NZ707174A (en) 2018-10-26
AU2013323349B2 (en) 2016-09-15
KR20220003640A (ko) 2022-01-10
RU2015114996A (ru) 2016-11-20
TWI732158B (zh) 2021-07-01
WO2014052780A2 (en) 2014-04-03
JP2016500660A (ja) 2016-01-14
AU2016216741B2 (en) 2018-02-15
KR20210009438A (ko) 2021-01-26
TW201924680A (zh) 2019-07-01
AU2013323349A1 (en) 2015-05-07
JP2018117625A (ja) 2018-08-02
PT3524260T (pt) 2023-10-13
DK3524260T3 (da) 2023-10-09
JP6779618B2 (ja) 2020-11-04
US11090292B2 (en) 2021-08-17
CN105072909A (zh) 2015-11-18
JP6796097B2 (ja) 2020-12-02
EP4302825A3 (en) 2024-07-03
KR20250048114A (ko) 2025-04-07
TW202106298A (zh) 2021-02-16
BR112015006282B1 (pt) 2021-11-23
MX2022015141A (es) 2023-02-01
KR20230097201A (ko) 2023-06-30
ES2959427T3 (es) 2024-02-26
WO2014052780A3 (en) 2014-06-26
KR20190143484A (ko) 2019-12-30
PL3524260T3 (pl) 2023-11-27
BR112015006282A2 (pt) 2017-07-04
RU2648958C2 (ru) 2018-03-28
AR092713A1 (es) 2015-04-29
AU2016216741A1 (en) 2016-09-15
US20140088139A1 (en) 2014-03-27
NZ746394A (en) 2019-01-25
EP3524260A1 (en) 2019-08-14
KR20150058345A (ko) 2015-05-28
AR123902A2 (es) 2023-01-25
TW201417812A (zh) 2014-05-16
TWI667024B (zh) 2019-08-01
EP2906041A4 (en) 2016-10-26
EP4302825A2 (en) 2024-01-10
MX2015003564A (es) 2015-11-16
CA2886091C (en) 2021-11-30

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