CN111387216A - Air sterilization and disinfection composition - Google Patents

Air sterilization and disinfection composition Download PDF

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Publication number
CN111387216A
CN111387216A CN202010296537.2A CN202010296537A CN111387216A CN 111387216 A CN111387216 A CN 111387216A CN 202010296537 A CN202010296537 A CN 202010296537A CN 111387216 A CN111387216 A CN 111387216A
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chlorite
disinfection
composition
chlorine dioxide
air
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Inventor
刘志强
万成松
卢广文
李国柱
张绪茂
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Guangdong Technetium Pharmaceutical Technology Research Institute Co ltd
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Guangdong Technetium Pharmaceutical Technology Research Institute Co ltd
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Priority to CN202010296537.2A priority Critical patent/CN111387216A/en
Publication of CN111387216A publication Critical patent/CN111387216A/en
Priority to CN202110388982.6A priority patent/CN113142250A/en
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/06Oxygen or sulfur directly attached to a cycloaliphatic ring system
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/22Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Pest Control & Pesticides (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Disinfection, Sterilisation Or Deodorisation Of Air (AREA)

Abstract

The invention belongs to the field of disinfection articles, and relates to a composition for air sterilization and disinfection. The air sterilization and disinfection composition comprises the following components: 50-75 wt% of a powder comprising a chlorite and an acidic substance; 1 to 5.5% by weight of menthol; 2-8% by weight of catnip powder; the balance of auxiliary materials. The air sterilization and disinfection composition disclosed by the invention is a composite component, has a mixture capable of generating chlorine dioxide and traditional Chinese medicine components which are matched with each other, and has the effects of soothing the nerves and relieving exterior syndrome while enhancing the sterilization and disinfection effects. Compared with single-component chlorine dioxide disinfectant, the novel composition provided by the invention is not only suitable for sterilizing and disinfecting air, but also has a protection function on influenza, respiratory virus infection and the like.

Description

Air sterilization and disinfection composition
Technical Field
The invention belongs to the field of disinfection articles, and relates to a composition for air sterilization and disinfection.
Background
Chlorine dioxide (ClO)2) Is a gas from yellow green to orange yellow, and is a safe and nontoxic green disinfectant which is internationally recognized. At present, chlorine dioxide is mainly used for bleaching pulp and paper, fiber, wheat flour and starch and disinfecting and sterilizing drinking water. Chlorine gas is used as a disinfectant, and some toxic byproducts are easily generated in the sterilization and disinfection process. Chlorine dioxide is a strong oxidant, and the available chlorine of the chlorine dioxide is 2.6 times of that of chlorine. In addition, chlorine dioxide does not react with organic matters in water to generate toxic and harmful organic chloride, so that chlorine dioxide gradually replaces chlorine gas to become a widely used sterilizing disinfectant.
A large number of foreign experimental studies show that chlorine dioxide is a safe and nontoxic disinfectant, has no carcinogenic, teratogenic and mutagenic effects, and does not generate chlorination reaction with organic matters during disinfection to generate organic chloride or other toxic substances capable of generating 'causing three effects'. However, chlorine dioxide is extremely strong in oxidizing power and should be avoided at high concentrations (> 500 ppm). When the concentration is lower than 500ppm, the influence on the human body can be ignored, and when the concentration is lower than 100ppm, the influence on the human body can not be generated, including the physiological and biochemical influences. It has no sensitization effect on skin. The concentration of chlorine dioxide used conventionally is far below 500ppm, generally only about tens of ppm. Therefore, chlorine dioxide is also internationally recognized as a safe, non-toxic, green disinfectant.
At present, chlorine dioxide is widely applied to the fields of disinfection of drinking water, sterilization of air, disinfection of kitchen utensils and food machinery equipment, disinfection of aquaculture and livestock breeding, formaldehyde removal of house furniture, odor removal and the like. However, chlorine dioxide has the limitations of difficult preparation, unstable properties, and explosiveness, which limits the mass production and application of chlorine dioxide. Industrial production of chlorine dioxide requires complex processes and specialized equipment, is explosive and does not allow compressed gas transport. Chlorine dioxide is very active, extremely unstable and difficult to store, and is generally prepared in situ at present. When a large amount of chlorine dioxide is continuously used, the chlorine dioxide generator can be used for generating chlorine dioxide and then directly introducing the chlorine dioxide into a using system, but the existing chlorine dioxide generator is not suitable for a system with relatively small using amount and dispersed using objects.
Most chlorine dioxide releasing agents are currently achieved in a more acidic solution by using so-called "stable chlorine dioxide solutions" or industrial sodium chlorite via an acidification process. However, these chlorine dioxide-releasing agents have a low utilization of less than 30%, which not only wastes large amounts of raw materials, but also large amounts of unconverted ClO2-Remain in the chlorine dioxide solution and the harmful ClO2-Are difficult to eliminate naturally. Thus, these chlorine dioxide-releasing agents are unacceptable as disinfectants.
Disclosure of Invention
The invention aims to provide an air sterilization and disinfection composition which can slowly release chlorine dioxide gas, has long duration and complete reaction, and has continuous sterilization and disinfection effects on the air of the surrounding environment.
The air sterilization and disinfection composition comprises the following components: 50-75 wt% of a powder comprising a chlorite and an acidic substance; 1 to 5.5% by weight of menthol; 2-8% by weight of catnip powder; the balance of auxiliary materials.
According to a further feature of the present invention, the air disinfecting composition comprises a powder of chlorite and an acidic material in a ratio of 1: 3-7 (weight ratio) of the above-mentioned materials.
Preferably, the chlorite is selected from: sodium chlorite, potassium chlorite, magnesium chlorite.
Preferably, the acidic substance is selected from: citric acid, citrate, boric acid, borate, oxalic acid, phosphoric acid, phosphate, dodecylbenzenesulfonic acid, sodium bisulfate, and sodium bicarbonate.
Preferably, the adjuvant comprises a stabilizer selected from the group consisting of: calcium carbonate, sodium thiosulfate, sodium percarbonate, sodium chloride and calcium oxide.
The air sterilization and disinfection composition is further characterized by also comprising 1-2 wt% of perfume.
Preferably, the perfume is derived from one or more of the following raw materials: lavender, jasmine, lemon essence, rose and sandalwood.
The air sterilization and disinfection composition has the following beneficial effects: the composition is a composite component, has a mixture capable of generating chlorine dioxide and traditional Chinese medicine components, and has the effects of calming the nerves and relieving exterior syndrome while enhancing the sterilization and disinfection effects. Compared with single-component chlorine dioxide disinfectant, the novel composition provided by the invention is not only suitable for sterilizing and disinfecting air, but also has a protection function on influenza, respiratory virus infection and the like.
Detailed Description
The present invention will be described in further detail below with reference to specific examples. The specific embodiments are provided to facilitate a better understanding of the present invention and are not intended to limit the present invention in any way.
The first embodiment is as follows: preparation of air sterilization and disinfection composition
Composition 1: 0.5 g of sodium chlorite, 1.5 g of citric acid, 0.22 g of menthol, 0.32 g of schizonepeta powder and 1.46 g of auxiliary materials, and the total weight is 4 g.
Composition 2: 0.45 g of sodium chlorite, 1.79 g of citric acid, 0.13 g of menthol, 0.2 g of schizonepeta powder and 1.43 g of auxiliary materials, and the total weight is 4 g.
Composition 3: 0.5 g of sodium chlorite, 2.5 g of citric acid, 0.04 g of menthol, 0.08 g of schizonepeta powder and 0.88 g of auxiliary materials, and the total weight is 4 g.
Composition 4: 0.2 g of sodium chlorite, 1.2 g of citric acid, 0.1 g of menthol, 0.04 g of schizonepeta powder and 0.46 g of auxiliary materials, and the total amount is 2 g.
Composition 5: 0.45 g of sodium chlorite, 3.15 g of citric acid, 0.33 g of menthol, 0.48 g of schizonepeta powder and 1.59 g of auxiliary materials, and the total weight is 6 g.
Composition 6: 2.8 g of sodium chlorite, 19.6 g of citric acid, 1.65 g of menthol, 2.4 g of schizonepeta powder and 3.55 g of auxiliary materials, and the total amount is 30 g.
Composition 7: 2.8 g of sodium chlorite, 19.6 g of citric acid, 1.65 g of menthol, 2.4 g of schizonepeta powder, 0.3 g of lemon essence and 3.25 g of auxiliary materials, and the total amount is 30 g.
Composition 8: 2.8 g of sodium chlorite, 19.6 g of citric acid, 1.65 g of menthol, 2.4 g of schizonepeta powder, 0.6 g of lemon essence and 2.95 g of auxiliary materials, and the total amount is 30 g.
The sodium chlorite used in this example may be replaced with potassium chlorite or magnesium chlorite.
The citric acid used in this example can be replaced by the following acidic substances: citrate, boric acid, borate, oxalic acid, phosphoric acid, phosphate, dodecylbenzene sulfonic acid, sodium bisulfate, sodium bicarbonate.
The auxiliary materials used in this embodiment may be selected from: calcium carbonate, sodium thiosulfate, sodium percarbonate, sodium chloride and calcium oxide.
The air sterilization and disinfection composition is further characterized by also comprising 1-2 wt% of perfume.
The lemon essence used in this embodiment may be other flavors, such as those derived from lavender, jasmine, rose, sandalwood, etc.
The components are mixed to obtain the air sterilization and disinfection composition.
Example two: effect experiment of the air sterilizing and disinfecting composition
Compositions 1 to 6 prepared in example one were selected and packed in a breathable bag for effect experiments.
The detection basis is as follows: GB 15979-2002 sanitary Standard for Disposable sanitary articles.
Detecting the environment: the temperature is 20-30 ℃, and the relative humidity is 50-75%.
These compositions were tested to provide sustained release of chlorine dioxide, menthol volatiles, and catmint volatiles.
And (3) detection results: the bacteriostasis rate of the escherichia coli is more than 99.9%; the bacteriostasis rate of staphylococcus aureus is more than 99.9 percent.
Figure 306072DEST_PATH_IMAGE001
Menthol is the major component of essential oils of peppermint and peppermint, and exists in both free and esterified states. Menthol is used as an aromatizer for toothpastes, perfumes, beverages, candies, and the like; it can be used as irritant in medicine, and has effects of refreshing and relieving itching. The menthol can be obtained by purifying natural peppermint crude oil or by synthesis.
Menthol is one of the components of exterior-releasing medicines, can disperse exterior pathogens and release exterior syndromes, and has the effects of sweating, relieving fever, resisting inflammation and easing pain. Menthol is a fat-soluble substance that has a damaging effect on the viral envelope. Menthol is a volatile aromatic substance, promotes the release of chlorine dioxide, and plays a role in expanding and dredging nasal mucosa.
Herba schizonepetae is one of the commonly used herbal medicines for sweating and relieving fever, and can be used for relieving phlegm, dispelling wind and cooling blood, and treating influenza, headache, cold and heat, sweating and vomiting.
The invention adopts the combination of the menthol and the schizonepeta, because the schizonepeta also has the same exterior-releasing effect as the menthol, and meanwhile, the schizonepeta is added to adjust the using amount of the menthol in the composition, so that the schizonepeta-containing composition is suitable for people with strong menthol allergy, and can avoid the excessive stimulation of the menthol.

Claims (7)

1. An air disinfecting composition comprising: 50-75 wt% of a powder comprising a chlorite and an acidic substance; 1 to 5.5% by weight of menthol; 2-8% by weight of catnip powder; the balance of auxiliary materials.
2. An air disinfecting composition as claimed in claim 1, wherein: the powder is prepared from chlorite and an acidic substance according to the weight ratio of 1: 3-7 (weight ratio) of the above-mentioned materials.
3. An air disinfecting composition as claimed in claim 1 or claim 2 wherein the chlorite is selected from: sodium chlorite, potassium chlorite, magnesium chlorite.
4. An air sterilizer composition according to claim 1 or 2, wherein: the acidic substance is selected from: citric acid, citrate, boric acid, borate, oxalic acid, phosphoric acid, phosphate, dodecylbenzenesulfonic acid, sodium bisulfate, and sodium bicarbonate.
5. An air disinfecting composition as claimed in claim 1, wherein: the auxiliary material comprises a stabilizer selected from: calcium carbonate, sodium thiosulfate, sodium percarbonate, sodium chloride and calcium oxide.
6. An air disinfecting composition as claimed in claim 1, wherein: and 1-2 wt% of perfume.
7. An air disinfecting composition as claimed in claim 1, wherein: the spice is one or more than one of the following raw materials: lavender, jasmine, lemon essence, rose and sandalwood.
CN202010296537.2A 2020-04-15 2020-04-15 Air sterilization and disinfection composition Pending CN111387216A (en)

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CN202110388982.6A CN113142250A (en) 2020-04-15 2021-04-12 Air sterilization and disinfection composition

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CN117530291A (en) * 2023-11-10 2024-02-09 广州荃智美肤生物科技研究院有限公司 Activation-free slow-release air disinfectant and preparation method thereof

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