CN111345326A - Natural plant disinfection effervescent tablet and preparation method thereof - Google Patents

Natural plant disinfection effervescent tablet and preparation method thereof Download PDF

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Publication number
CN111345326A
CN111345326A CN202010242307.8A CN202010242307A CN111345326A CN 111345326 A CN111345326 A CN 111345326A CN 202010242307 A CN202010242307 A CN 202010242307A CN 111345326 A CN111345326 A CN 111345326A
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parts
effervescent
tablet
powder
natural plant
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陈卫东
陈艳丽
蒲济林
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GANSU VOCATIONAL & TECHNICAL COLLEGE OF NONFERROUS METALLURGY
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GANSU VOCATIONAL & TECHNICAL COLLEGE OF NONFERROUS METALLURGY
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/34Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/06Oxygen or sulfur directly attached to a cycloaliphatic ring system
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/12Asteraceae or Compositae [Aster or Sunflower family], e.g. daisy, pyrethrum, artichoke, lettuce, sunflower, wormwood or tarragon
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/28Myrtaceae [Myrtle family], e.g. teatree or clove
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/40Liliopsida [monocotyledons]
    • A01N65/42Aloeaceae [Aloe family] or Liliaceae [Lily family], e.g. aloe, veratrum, onion, garlic or chives
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/40Liliopsida [monocotyledons]
    • A01N65/44Poaceae or Gramineae [Grass family], e.g. bamboo, lemon grass or citronella grass
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/40Liliopsida [monocotyledons]
    • A01N65/48Zingiberaceae [Ginger family], e.g. ginger or galangal

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pest Control & Pesticides (AREA)
  • Botany (AREA)
  • Toxicology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a natural plant disinfection effervescent tablet and a preparation method thereof, belonging to the field of disinfectants. The effervescent disinfectant tablet comprises folium Eucalypti Robustae, herba Cymbopogonis Citrari, folium Artemisiae Argyi, rhizoma Zingiberis recens, Bulbus Allii Cepae, Bulbus Allii, herba Verbenae, effervescent disintegrant and binder. The invention adopts a plurality of natural Chinese herbal medicine plants as raw materials to prepare the disinfection effervescent tablet, has wide raw material sources, low cost, good disinfection and sterilization effect of the finished product, no harm and stimulation to human bodies, no pollution to the environment, convenient carrying and storage, and is not easy to cause fire because of adopting low-concentration alcohol in the dilution use process.

Description

Natural plant disinfection effervescent tablet and preparation method thereof
Technical Field
The invention belongs to the field of disinfectants, and particularly relates to a natural plant disinfection effervescent tablet and a preparation method thereof.
Background
The disinfectant is used for killing pathogenic microorganisms on a transmission medium, so that the requirement of harmlessness is met, the pathogenic microorganisms are killed out of a human body, the transmission path of infectious diseases is cut off, and the purpose of controlling the infectious diseases is achieved.
The disinfectant can be divided into a sterilizing agent, a high-efficiency disinfectant, a middle-efficiency disinfectant and a low-efficiency disinfectant according to the action level. The sterilizing agent can kill all microorganisms to meet the sterilizing requirement, and comprises formaldehyde, glutaraldehyde, ethylene oxide, peracetic acid, hydrogen peroxide, chlorine dioxide, chlorine, copper sulfate, quicklime, ethanol and the like. The disinfectant is usually called chemical disinfectant, has simple synthesis process and low price, but has certain toxicity and irritation and corrosiveness to human bodies.
The effervescent tablet is different from the common tablet, and the effervescent tablet uses the reaction of organic acid and alkali carbonate as an effervescent disintegrant, is put into water, and immediately generates an effervescent reaction to generate and release a large amount of carbon dioxide gas which is boiled, so the effervescent tablet is named. The prescription of the effervescent tablet consists of main drugs, diluent, adhesive, disintegrant, lubricant and other auxiliary materials.
Related patents related to disinfection effervescent tablets are disclosed in the prior art, for example, CN110810436 discloses a disinfection effervescent tablet and a preparation method and application thereof, and the components of the disinfection effervescent tablet comprise potassium monopersulfate, organic acid, carbonate and effervescent tablet auxiliary materials. CN103907598 discloses a chlorine disinfectant effervescent tablet, which comprises isocyanuric acid chloride, an effervescent agent, a lubricant and an adhesive, wherein the isocyanuric acid chloride is prepared from sodium dichloroisocyanurate and trichloroisocyanuric acid according to a weight ratio of 1 (0.5-3). CN101496530 provides a hydantoin compound effervescent disinfectant tablet and its preparation method, the compound effervescent disinfectant tablet comprises hydantoin bromine-containing compounds, antibacterial Chinese medicinal extracts and effervescent tablet accessories, wherein the antibacterial Chinese medicinal extracts concentration is 1g of effervescent tablets containing 0.1-10 g of crude drugs, 3-30 wt%, hydantoin bromine-containing compounds 0.1-30 wt%, and the balance effervescent tablet accessories. The disinfection effervescent tablets are mainly organic chemical components, have obvious effects but high toxicity, are very easy to damage the respiratory system and the digestive system of a human body when being sprayed in the air, and harm the environment. Therefore, it is very important to research a disinfectant which is non-toxic and harmless to human bodies and the environment, has no side effect and has good sterilization effect.
Disclosure of Invention
The invention aims to provide a natural plant disinfection effervescent tablet and a preparation method thereof aiming at the defects of the existing disinfection effervescent tablet.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows: a natural plant disinfection effervescent tablet is prepared from the following components in parts by mass: 15-20 parts of eucalyptus robusta leaves, 10-20 parts of lemongrass, 10-15 parts of folium artemisiae argyi, 5-20 parts of ginger, 10-15 parts of onion, 5-20 parts of garlic, 1-15 parts of verbena, 20-40 parts of effervescent disintegrant and 5-10 parts of adhesive.
Preferably, the natural plant disinfection effervescent tablet is prepared from the following components in parts by mass: 17.5 parts of eucalyptus robusta leaves, 15 parts of lemongrass, 12.5 parts of folium artemisiae argyi, 15 parts of ginger, 12 parts of onion, 12 parts of garlic, 10 parts of verbena, 30 parts of effervescent disintegrant and 6 parts of adhesive.
The invention also provides a preparation method of the natural plant disinfection effervescent tablet, which comprises the following steps:
s1, cleaning folium Eucalypti Robustae, herba Cymbopogonis Citrari, folium Artemisiae Argyi, rhizoma Zingiberis recens, Bulbus Allii Cepae, Bulbus Allii, and herba Verbenae, oven drying, weighing, mixing, pulverizing into powder in a low temperature ultrafine pulverizer to obtain main drug powder, adding ethanol, ultrasonic pulverizing in an ultrasonic cell pulverizer, concentrating, and vacuum spray drying to obtain main drug extract powder;
s2, uniformly mixing the main material extract powder with the effervescent disintegrant and the adhesive, and putting the mixture into a tablet press for tabletting to obtain a finished product of 2-4 g/tablet.
Preferably, in step S1, the temperature of the low-temperature ultrafine pulverizer during the pulverization treatment is from-10 ℃ to-50 ℃.
Preferably, in step S1, the volume concentration of ethanol is 30-80%, and the dosage is 2-5 times of the mass of the main drug powder.
Preferably, in the step S1, the temperature used for the ultrasonic treatment in the ultrasonic cell crusher is 30 to 65 ℃, and the treatment time is 60 to 120 min.
The use method of the natural plant disinfection effervescent tablet comprises the following steps: the natural plant disinfection effervescent tablets are diluted in 100-1000 ml of ethanol solution with volume concentration not higher than 15%, and then sprayed into the air.
In some embodiments of the invention, the natural plant disinfection effervescent tablet further comprises, by mass, 1 to 2 parts of natural borneol, 0.1 to 0.5 part of elsholtzia volatile oil, 0.1 to 0.3 part of costus root volatile oil, 0.2 to 0.4 part of mint volatile oil, and 3 to 20 parts of hydroxypropyl- β -cyclodextrin.
Further, adding a small amount of absolute ethyl alcohol into the natural borneol, the elsholtzia volatile oil, the elecampane volatile oil and the mint volatile oil for dissolving, adding the dissolved natural borneol, the elsholtzia volatile oil, the elecampane volatile oil and the mint volatile oil into an aqueous solution of hydroxypropyl- β -cyclodextrin, uniformly mixing, placing the mixture into an ultrasonic cell crusher for ultrasonic treatment, performing ultrasonic treatment for 20-40min, performing vacuum freeze drying, crushing, sieving by 80-200 meshes to obtain traditional Chinese medicine inclusion powder, uniformly mixing the traditional Chinese medicine inclusion powder with the main material extraction powder, the effervescent disintegrant and the adhesive, and then placing the mixture into a tablet tabletting machine for tabletting to obtain a finished product of.
In summary, due to the adoption of the technical scheme, the invention has the beneficial effects that: the invention adopts a plurality of natural Chinese herbal medicine plants as raw materials to prepare the disinfection effervescent tablet, has wide raw material sources, low cost, good disinfection and sterilization effect of the finished product, no harm and stimulation to human bodies, no pollution to the environment, convenient carrying and storage, and is not easy to cause fire because of adopting low-concentration alcohol in the dilution use process.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Example 1
Weighing 15 parts of eucalyptus robusta leaves, 10 parts of lemongrass, 10 parts of folium artemisiae argyi, 5 parts of ginger, 15 parts of onion, 10 parts of garlic and 5 parts of verbena according to the mass parts, cleaning and drying the components in advance, freezing the raw materials to-10 ℃ in an ultramicro crusher, grinding the raw materials into powder to obtain main medicine powder, adding ethanol with the volume concentration of 50%, controlling the ultrasonic temperature at 60 ℃ in an ultrasonic cell crusher, carrying out ultrasonic treatment for 30min, concentrating, and carrying out freeze drying in a vacuum spray dryer to obtain main material extract powder. And uniformly mixing the main material extract powder, 25 parts of effervescent disintegrant and 15 parts of adhesive, and putting the mixture into a tablet press for tabletting to obtain a finished product of 2 g/tablet.
When in use, 1 tablet of the effervescent disinfectant tablet is diluted in 1000ml of 15% ethanol solution with volume concentration, and then sprayed into the air, so that disinfection and sterilization can be realized.
Example 2
Weighing 20 parts of eucalyptus robusta leaves, 15 parts of lemongrass, 10 parts of folium artemisiae argyi, 5 parts of ginger, 10 parts of onion, 5 parts of garlic and 10 parts of verbena according to the mass parts, cleaning and drying the components in advance, freezing the raw materials to-50 ℃ in an ultramicro crusher, grinding the raw materials into powder to obtain main material powder, adding ethanol with the volume concentration of 30%, controlling the ultrasonic temperature at 50 ℃ in an ultrasonic cell crusher, carrying out ultrasonic treatment for 90min, concentrating, and carrying out freeze drying in a vacuum spray dryer to obtain main material extract powder. And uniformly mixing the main material extract powder, 30 parts of effervescent disintegrant and 10 parts of adhesive, and putting the mixture into a tablet tabletting machine for tabletting to obtain a finished product of 4 g/tablet.
When in use, 1 disinfection effervescent tablet of the embodiment is put into 500ml of ethanol solution with volume concentration of 15 percent for dilution, and then is sprayed into the air, thus disinfection and sterilization can be realized.
Example 3
Weighing 17.5 parts of cleaned and dried eucalyptus robusta leaves, 15 parts of lemongrass, 12.5 parts of folium artemisiae argyi, 15 parts of ginger, 12 parts of onion, 12 parts of garlic, 10 parts of verbena, 30 parts of effervescent disintegrant, 6 parts of adhesive, 2 parts of natural borneol, 0.5 part of elsholtzia volatile oil, 0.3 part of elecampane volatile oil, 0.4 part of mint volatile oil and 20 parts of hydroxypropyl- β -cyclodextrin according to the mass parts, freezing folium eucalypti robusta, lemongrass, folium artemisiae argyi, ginger, onion, garlic and verbena raw materials in an ultramicro crusher to-30 ℃ and then crushing into powder to obtain main medicine powder, adding ethanol with the volume concentration of 50% into the main medicine powder, controlling the ultrasonic temperature at 40 ℃ and the ultrasonic time at 30min, concentrating, freeze-drying in a vacuum spray dryer to obtain main material extract powder, dissolving hydroxypropyl- β -cyclodextrin into a proper amount of water to obtain an aqueous solution of hydroxypropyl- β -cyclodextrin, taking the natural borneol, volatile oil, the essential oil, the peppermint volatile oil, the essential oil, the auxiliary material extract powder, the auxiliary material, the aqueous solution, the.
The herba elsholtziae volatile oil, the radix aucklandiae volatile oil and the mint volatile oil are extracted by a supercritical CO2 extraction method.
When in use, 1 tablet of the effervescent disinfectant tablet is diluted in 1000ml of 15% ethanol solution with volume concentration, and then sprayed into the air, so that disinfection and sterilization can be realized.
Test examples
The natural plant disinfection effervescent tablets prepared in example 3 are diluted and then subjected to a microorganism killing test.
The test conditions are as follows: under the condition of water bath at 20 ℃, 0.5ml of bacterial suspension and 5ml of the diluted disinfectant of experimental example 3 are added into a sterile test tube and mixed, and the action time is as follows: 5. 10, 20 min; wherein, the selected test bacteria strains are staphylococcus aureus, streptococcus A and escherichia coli, and the average killing logarithm value is calculated after the viable bacteria are cultured and counted.
Time of action Staphylococcus aureus Group A streptococcus Escherichia coli
5min 6.0 5.0 5.6
10min 8.3 7.6 7.4
20min 13.1 12.6 12.2
The natural plant disinfection effervescent tablet of the embodiment 3 of the invention has the average killing logarithm value of not less than 6.0 to staphylococcus aureus, the average killing logarithm value of not less than 5.0 to streptococcus A and the average killing logarithm value of not less than 5.6 to escherichia coli after being diluted.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included within the scope of the present invention.

Claims (9)

1. The natural plant disinfection effervescent tablet is characterized by being prepared from the following components in parts by mass: 15-20 parts of eucalyptus robusta leaves, 10-20 parts of lemongrass, 10-15 parts of folium artemisiae argyi, 5-20 parts of ginger, 10-15 parts of onion, 5-20 parts of garlic, 1-15 parts of verbena, 20-40 parts of effervescent disintegrant and 5-10 parts of adhesive.
2. The natural plant disinfection effervescent tablet of claim 1, which is prepared from the following components in parts by mass: 17.5 parts of eucalyptus robusta leaves, 15 parts of lemongrass, 12.5 parts of folium artemisiae argyi, 15 parts of ginger, 12 parts of onion, 12 parts of garlic, 10 parts of verbena, 30 parts of effervescent disintegrant and 6 parts of adhesive.
3. A method for preparing natural plant disinfectant effervescent tablets as claimed in claim 1, comprising the steps of:
s1, cleaning folium Eucalypti Robustae, herba Cymbopogonis Citrari, folium Artemisiae Argyi, rhizoma Zingiberis recens, Bulbus Allii Cepae, Bulbus Allii, and herba Verbenae, oven drying, weighing, mixing, pulverizing into powder in a low temperature ultrafine pulverizer to obtain main drug powder, adding ethanol, ultrasonic pulverizing in an ultrasonic cell pulverizer, concentrating, and vacuum spray drying to obtain main drug extract powder;
s2, uniformly mixing the main material extract powder with the effervescent disintegrant and the adhesive, and putting the mixture into a tablet press for tabletting to obtain a finished product of 2-4 g/tablet.
4. A method as claimed in claim 3, characterized by: in the step S1, the temperature of the low-temperature ultrafine grinder during the grinding treatment is-10 to-50 ℃.
5. A method as claimed in claim 3, characterized by: in the step S1, the volume concentration of the ethanol is 30-80%, and the dosage of the ethanol is 2-5 times of the mass of the main medicine powder.
6. A method as claimed in claim 3, characterized by: in the step S1, the temperature adopted for ultrasonic treatment in the ultrasonic cell crusher is 30-65 ℃, and the treatment time is 60-120 min.
7. A method of using the natural plant effervescent disinfectant tablet as claimed in claim 1, wherein: the natural plant disinfection effervescent tablets are diluted in 100-1000 ml of ethanol solution with volume concentration not higher than 15%, and then sprayed into the air.
8. The natural plant disinfection effervescent tablet of claim 1, further comprising 1-2 parts by mass of natural borneol, 0.1-0.5 part by mass of elsholtzia volatile oil, 0.1-0.3 part by mass of elecampane volatile oil, 0.2-0.4 part by mass of mint volatile oil, and 3-20 parts by mass of hydroxypropyl- β -cyclodextrin.
9. A process for preparing a natural plant effervescent disinfectant tablet as claimed in claim 8, comprising the steps of:
s1, cleaning folium Eucalypti Robustae, herba Cymbopogonis Citrari, folium Artemisiae Argyi, rhizoma Zingiberis recens, Bulbus Allii Cepae, Bulbus Allii, and herba Verbenae, oven drying, weighing, mixing, pulverizing into powder in a low temperature ultrafine pulverizer to obtain main drug powder, adding ethanol, ultrasonic pulverizing in an ultrasonic cell pulverizer, concentrating, and vacuum spray drying to obtain main drug extract powder;
s2, adding natural borneol, elsholtzia volatile oil, elecampane volatile oil and mint volatile oil into a small amount of absolute ethyl alcohol for dissolving, adding the dissolved mixture into a water solution of hydroxypropyl- β -cyclodextrin, uniformly mixing, placing the mixture into an ultrasonic cell crusher for ultrasonic treatment, carrying out ultrasonic treatment for 20-40min, carrying out vacuum freeze drying, crushing, and sieving by 80-200 meshes to obtain traditional Chinese medicine inclusion powder;
s3, uniformly mixing the traditional Chinese medicine inclusion powder with the main material extraction powder, the effervescent disintegrant and the adhesive, and putting the mixture into a tablet tabletting machine for tabletting to obtain a finished product of 2-4 g/tablet.
CN202010242307.8A 2020-03-31 2020-03-31 Natural plant disinfection effervescent tablet and preparation method thereof Pending CN111345326A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112450230A (en) * 2020-11-03 2021-03-09 南京植创生物技术研究院有限公司 Compound plant disinfectant and preparation method thereof
CN113170803A (en) * 2021-04-29 2021-07-27 中国人民解放军联勤保障部队第九〇九医院 Household compound distillate for preventing pestilence and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102845486A (en) * 2012-08-14 2013-01-02 青岛叁鼎卫生制品有限公司 Herbal disinfectant
CN106538638A (en) * 2016-11-02 2017-03-29 李湘钰 A kind of Chinese medicine antiseptic and preparation method thereof
CN106665671A (en) * 2016-12-30 2017-05-17 南宁天亮精细化工有限责任公司 Eucalyptus robusta sterilization spray for dwelling houses
CN106719955A (en) * 2016-12-24 2017-05-31 张涉应 A kind of plant disinfectant
CN110896969A (en) * 2018-09-17 2020-03-24 中国医学科学院药用植物研究所 Green slow-release disinfection effervescent tablet and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102845486A (en) * 2012-08-14 2013-01-02 青岛叁鼎卫生制品有限公司 Herbal disinfectant
CN106538638A (en) * 2016-11-02 2017-03-29 李湘钰 A kind of Chinese medicine antiseptic and preparation method thereof
CN106719955A (en) * 2016-12-24 2017-05-31 张涉应 A kind of plant disinfectant
CN106665671A (en) * 2016-12-30 2017-05-17 南宁天亮精细化工有限责任公司 Eucalyptus robusta sterilization spray for dwelling houses
CN110896969A (en) * 2018-09-17 2020-03-24 中国医学科学院药用植物研究所 Green slow-release disinfection effervescent tablet and preparation method thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
周秋丽编著: "《现代中药基础研究与临床》", 30 June 2012, 天津科技翻译出版公司 *
江西药科学校革委会编: "《中草药学 试用教材》", 31 January 1971, 江西新华印刷厂 *
熊辅信等: "《中药现代研究荟萃》", 31 May 2002, 云南科学技术出版社 *
薛广波: "《现代消毒学》", 31 July 2002, 人民军医出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112450230A (en) * 2020-11-03 2021-03-09 南京植创生物技术研究院有限公司 Compound plant disinfectant and preparation method thereof
CN113170803A (en) * 2021-04-29 2021-07-27 中国人民解放军联勤保障部队第九〇九医院 Household compound distillate for preventing pestilence and preparation method thereof

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Application publication date: 20200630