CN111317756A - A Chinese medicinal composition liquid blasting bead for mask and its preparation method - Google Patents
A Chinese medicinal composition liquid blasting bead for mask and its preparation method Download PDFInfo
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- CN111317756A CN111317756A CN202010321154.6A CN202010321154A CN111317756A CN 111317756 A CN111317756 A CN 111317756A CN 202010321154 A CN202010321154 A CN 202010321154A CN 111317756 A CN111317756 A CN 111317756A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/01—Deodorant compositions
- A61L9/012—Deodorant compositions characterised by being in a special form, e.g. gels, emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/01—Deodorant compositions
- A61L9/013—Deodorant compositions containing animal or plant extracts, or vegetable material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2209/00—Aspects relating to disinfection, sterilisation or deodorisation of air
- A61L2209/20—Method-related aspects
- A61L2209/21—Use of chemical compounds for treating air or the like
Abstract
A Chinese medicinal liquid composition for gauze mask explodes pearl and its preparation method, involve the medical technical field, after the Chinese medicinal liquid composition prepared of the invention explodes the pearl and is pinched, because the Chinese medicinal liquid composition has effects of antibacterial, antiviral and fresh smell, Chinese medicinal liquid composition especially Chinese medicinal volatile oil is applied to the gauze mask, can freshen the air, can suck the volatile oil into the respiratory tract, block the invasion of virus in the air to the human body, Chinese medicinal volatile oil enters the blood circulation system through the mucosa of respiratory tract and pulmonary capillary, realize the virus protection to eyes, oral area indirectly, etc., the invention has easy to operate, safe non-toxic, convenient and fashionable characteristic, conform to people's frequent use habit at present, there are very large market prospects.
Description
Technical Field
The invention relates to the technical field of medicines, in particular to a traditional Chinese medicine combination liquid blasting bead for a mask and a preparation method thereof.
Background
As known, a mask is a sanitary product, and generally refers to a device worn at the mouth and nose for filtering air entering the mouth and nose to block harmful gas, smell and spray from entering and exiting the mouth and nose of a wearer, and is made of gauze or paper. The mask can effectively intercept particles with different sizes, reduce diseases caused by air pollution and block the occurrence of spreading diseases. The mask has a certain filtering function on air entering the lung, and has a very good effect when being worn in respiratory infectious diseases and working in environments polluted by dust and the like. Particularly, the recent global outbreak of novel coronavirus makes the mask wearing become the standard of people.
The popping beads, also called as aromatic pills, brittle capsules and beads, are sealed brittle capsules formed by wrapping essence and flavor with high molecular polymers, and are mainly applied to cigarette products at present.
According to the search, no patent application for applying the popple made of the volatile oil of the traditional Chinese medicine to the mask exists at present, and no report for realizing the health care function by combining the popple and the mask is found. Therefore, how to provide the traditional Chinese medicine combination liquid blasting bead for the mask and the preparation method thereof become a long-term technical demand of technical personnel in the field.
Disclosure of Invention
The traditional Chinese medicine combination liquid blasting bead for the mask and the preparation method thereof are provided for overcoming the defects in the background art, the traditional Chinese medicine combination liquid blasting bead prepared by the invention can release the smell of the traditional Chinese medicine combination liquid after being pinched and blasted, the liquid medicine is safely, effectively and directly acted in the whole respiratory tract range, and the effects of refreshing air, relieving headache and dizziness, cough, excessive phlegm, pharynx itch, dry mouth and the like can be achieved through the blood circulation system of a human body.
In order to achieve the above purpose, the invention adopts the following technical scheme:
the traditional Chinese medicine combination liquid blasting bead for the mask comprises the following components in percentage by mass:
1-3 parts of eucalyptus oil;
1-3 parts of peppermint oil;
1-3 parts of spruce oil;
6-10 parts of edible gel;
3-7 parts of edible gelatin.
The traditional Chinese medicine composition liquid for the mask explodes the beads, and the edible gel is preferably 8 parts.
The traditional Chinese medicine combination liquid for the mask is preferably 5 parts of edible gelatin.
A preparation method of a traditional Chinese medicine combination liquid blasting bead for a mask comprises the following steps:
firstly, weighing the following raw materials in percentage by mass:
firstly, weighing 1-3 parts of eucalyptus oil, 1-3 parts of peppermint oil, 1-3 parts of spruce oil, 6-10 parts of edible gel and 3-7 parts of edible gelatin;
step two, heating the edible gel and the edible gelatin to 70-80 ℃, mixing and stirring uniformly after the edible gel and the edible gelatin are completely dissolved to form a glue solution, mixing and stirring uniformly eucalyptus oil, peppermint oil and spruce oil, and reducing the heating temperature to obtain a molten liquid;
and thirdly, the step of the previous step, injecting the fusion liquid cooled to 20-40 ℃ into dripping pill equipment, and dripping the fusion liquid into a mould for pre-molding to obtain the required traditional Chinese medicine combination liquid blasting beads.
According to the preparation method of the traditional Chinese medicine combination liquid blasting bead for the mask, the diameter of the traditional Chinese medicine combination liquid blasting bead is 2 mm.
The preparation method of the traditional Chinese medicine combination liquid blasting bead for the mask is characterized in that the bead dropping device is a bead dropping machine.
By adopting the technical scheme, the invention has the following advantages:
after the traditional Chinese medicine combination liquid prepared by the invention is exploded by bead-blasting, the traditional Chinese medicine combination liquid has the functions of antibiosis, antivirus and fresh smell, the traditional Chinese medicine combination liquid, especially the traditional Chinese medicine volatile oil is applied to the mask, not only can air be refreshed, but also the volatile oil can be inhaled into the respiratory tract, the invasion of virus in the air to the human body can be blocked, the traditional Chinese medicine volatile oil enters a blood circulation system through respiratory tract mucosa and pulmonary capillary, the virus protection to eyes and mouths and the like can be indirectly realized, the traditional Chinese medicine combination liquid has the characteristics of simple operation, safety, no toxicity, convenience, fashion and the like, conforms to the current habit of frequently using the mask.
Detailed Description
The present invention will be explained in more detail by the following examples, which are not intended to limit the invention;
the traditional Chinese medicine combination liquid blasting bead for the mask comprises the following components in percentage by mass:
1-3 parts of eucalyptus oil; 1-3 parts of peppermint oil; 1-3 parts of spruce oil;
6-10 parts of edible gel; 3-7 parts of edible gelatin.
In specific implementation, the edible gel is preferably 8 parts; the edible gelatin is preferably 5 parts.
The eucalyptus oil contains the main components of 1, 8-cineole, limonene, α -terpinyl acetate, borneol and the like, has various physiological and biological activities, and the 1, 8-cineole has wide antibacterial action and is an effective antibacterial enhancer at the same time.
A preparation method of a traditional Chinese medicine combination liquid blasting bead for a mask comprises the following steps:
firstly, weighing the following raw materials in percentage by mass:
firstly, weighing 1-3 parts of eucalyptus oil, 1-3 parts of peppermint oil, 1-3 parts of spruce oil, 6-10 parts of edible gel and 3-7 parts of edible gelatin;
step two, heating the edible gel and the edible gelatin to 70-80 ℃, mixing and stirring uniformly after the edible gel and the edible gelatin are completely dissolved to form a glue solution, mixing and stirring uniformly eucalyptus oil, peppermint oil and spruce oil, and reducing the heating temperature to obtain a molten liquid;
and thirdly, the step is connected, the fusion liquid cooled to 20-40 ℃ is injected into pill dropping equipment, the pill dropping equipment is a pill dropping machine, the diameter of a mould in the pill dropping machine is 2mm, and the fusion liquid is dropped into the mould for pre-molding to obtain the traditional Chinese medicine combination liquid blasting beads with the diameter of 2 mm.
Then, putting 30-60 Chinese medicinal composition liquid beads into cotton cores of the filter disc of the inlet cover to obtain bead-blasting gaskets, and then putting the bead-blasting gaskets into an aluminum bag for packaging.
The invention takes the application on a mask as an example, two filter piece pockets are arranged at the nostril position of a cotton mask, filter pieces are made of cotton cloth with high air permeability, Chinese medicinal composition liquid blasting beads are arranged between the surface layer and the cotton core layer, each filter piece is internally provided with 30-60 Chinese medicinal composition liquid blasting beads, the filter pieces are independently packaged by aluminum bags, when in use, the aluminum bags are disassembled, the filter pieces are arranged in the mask, and then the Chinese medicinal composition liquid blasting beads are pinched to volatilize the liquid atmosphere in the filter pieces, so that the curative effect is exerted through the breathing action of the mouth and the nose. The traditional Chinese medicine combination liquid bead-explosion aluminum bag can seal the traditional Chinese medicine combination liquid bead-explosion, can avoid the direct contact of the liquid with light, heat or air, inhibit the volatilization and oxidation of the liquid, and effectively maintain the functions of the traditional Chinese medicine combination. The packaging form is convenient for carrying and using the fragile blasting bead, and improves the practicability of the invention. The bead blasting gasket can be replaced after being used for 7-8 hours, the bead blasting gasket adopts natural plant extraction raw materials, has the effects of sterilizing, preventing virus invasion and refreshing breath peculiar smell, and can improve the utilization rate of a single mask.
The study examples of the present invention are as follows:
example 1:
the composition is prepared from the following raw materials in parts by weight: 1 part of eucalyptus oil, 1 part of peppermint oil and 1 part of spruce oil; the composition can improve mental fatigue symptoms, and has remarkable anti-mental fatigue effect;
forced mouse swimming experiment: healthy male mice were selected and randomly divided into a blank control group and an administration group (given 15 μ L); distilled water control group (given 15. mu.L distilled water). The mice were placed in a cylindrical forced swimming tester with a water depth of 15 cm and a water temperature of 25 + -1 deg.C. And (4) carrying out forced swimming for 6 min, recording the cumulative immobile time within 5 min, and keeping the mouse in an immobile state when the mouse is raised and floats on the water surface. The results are shown in Table 1. Compared with a blank control group, the difference of the immobility time of the distilled water administration group has no statistical significance, and the immobility time of the mice is obviously shortened (p is less than 0.01) by inhaling the combined medicament of the invention. The combination drug of the invention has obvious anti-fatigue effect.
TABLE 1 Effect of nasal inhalation combination on immobility time in forced swimming of mice
| Group of | Inhalation concentration (μ L/L) | Dead time(s) |
| Blank control group | 0 | 230±15.2 |
| Distilled water control group | 0 | 235±20.6 |
| Combination drug group | 15 | 162±16.5** |
Note: p < 0.01 in comparison with control blank
Example 2:
the composition is prepared from the following raw materials in parts by weight: 3 parts of eucalyptus oil, 2 parts of peppermint oil and 1 part of spruce oil;
the composition has antibacterial and antiviral effects;
the combined medicament of the invention has the inhibition effect on Escherichia coli, and a control group (distilled water replaces the combined medicament); experimental group (combined drug dilutions of the present invention). Both groups of media were placed in an incubator and incubated at 37 ℃ for a further 24 h. Experimental results show that the medicine has a remarkable inhibiting effect on Escherichia coli.
Example 3:
the composition is prepared from the following raw materials in parts by weight: 1 part of eucalyptus oil, 2 parts of peppermint oil and 3 parts of spruce oil;
heating edible gel and edible gelatin to 70-80 deg.C, dissolving completely to form glue solution, mixing, stirring, mixing oleum Eucalypti, oleum Menthae Dementholatum and spruce oil, stirring, and adding, and lowering heating temperature.
Then the molten liquid cooled to 30 ℃ is injected into a pill dropping machine, a mould with the diameter of 2mm for pill making is prepared, and the glue solution is dripped into the mould for pre-molding.
And (3) putting 30-60 water gel pills into the cotton core of the filter disc of the inlet cover to obtain a bead blasting gasket, and then putting the bead blasting gasket into an aluminum bag for packaging.
The mask filter sheet is put into a mouth mask, experimenters test, 30 experimenters with cough, expectoration, nasal obstruction and nasal itching are selected, and the mask of the invention is selected to be continuously worn for 4 hours. The results are shown in Table 2.
Table 2 wearer experience questionnaire
| Number of coughs | Nasal cavity feeling | Nasal obstruction | Itching of nose | Smell perception | |
| Condition description | Is obviously reduced | Good effect | Cure of disease | Cure of disease | Good effect |
| Number of people (proportion) | 28（93.3%） | 30（100%） | 29（96.7%） | 28（93.3%） | 30（100%） |
| Discomfort | 0 | 0 | 0 | 0 | 0 |
The nasal cavity feels comfortable in ventilation and small in irritation. The odor perception refers to the degree of odor acceptance of the present combination drug. The condition of nasal congestion in the experience is a conscious feeling of inhaling. The experienced person's nasal itching condition is intermittent. The investigation results show that 100% of the people wearing the combined medicine mask have good nasal feeling, and 100% of the people have good acceptance of smell. The cure rate of the nasal obstruction and mild rhinocnesmus patients exceeds 93 percent. The number of coughs was significantly reduced in 93.3% of the population.
The present invention is not described in detail in the prior art.
The embodiments selected for the purpose of disclosing the invention, are presently considered to be suitable, it being understood, however, that the invention is intended to cover all variations and modifications of the embodiments which fall within the spirit and scope of the invention.
Claims (6)
1. A traditional Chinese medicine combination liquid blasting bead for a mask is characterized in that: the traditional Chinese medicine combination liquid blasting bead comprises the following components in percentage by mass:
1-3 parts of eucalyptus oil;
1-3 parts of peppermint oil;
1-3 parts of spruce oil;
6-10 parts of edible gel;
3-7 parts of edible gelatin.
2. The liquid blasting bead of traditional Chinese medicine for masks according to claim 1, which is characterized in that: the edible gel is preferably 8 parts.
3. The liquid blasting bead of traditional Chinese medicine for masks according to claim 1, which is characterized in that: the edible gelatin is preferably 5 parts.
4. The method for preparing a liquid blasting bead of a Chinese medicinal composition for a mask according to any one of claims 1 to 3, wherein the liquid blasting bead comprises the following steps: the preparation method specifically comprises the following steps:
firstly, weighing the following raw materials in percentage by mass:
firstly, weighing 1-3 parts of eucalyptus oil, 1-3 parts of peppermint oil, 1-3 parts of spruce oil, 6-10 parts of edible gel and 3-7 parts of edible gelatin;
step two, heating the edible gel and the edible gelatin to 70-80 ℃, mixing and stirring uniformly after the edible gel and the edible gelatin are completely dissolved to form a glue solution, mixing and stirring uniformly eucalyptus oil, peppermint oil and spruce oil, and reducing the heating temperature to obtain a molten liquid;
and thirdly, the step of the previous step, injecting the fusion liquid cooled to 20-40 ℃ into dripping pill equipment, and dripping the fusion liquid into a mould for pre-molding to obtain the required traditional Chinese medicine combination liquid blasting beads.
5. The method for preparing a liquid blasting bead of a traditional Chinese medicine composition for a mask according to claim 4, which is characterized in that: the diameter of the Chinese medicinal composition liquid bead is 2 mm.
6. The method for preparing a liquid blasting bead of a traditional Chinese medicine composition for a mask according to claim 4, which is characterized in that: the pill dropping equipment is a pill dropping machine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010321154.6A CN111317756A (en) | 2020-04-22 | 2020-04-22 | A Chinese medicinal composition liquid blasting bead for mask and its preparation method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010321154.6A CN111317756A (en) | 2020-04-22 | 2020-04-22 | A Chinese medicinal composition liquid blasting bead for mask and its preparation method |
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| Publication Number | Publication Date |
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| CN111317756A true CN111317756A (en) | 2020-06-23 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202010321154.6A Pending CN111317756A (en) | 2020-04-22 | 2020-04-22 | A Chinese medicinal composition liquid blasting bead for mask and its preparation method |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107982321A (en) * | 2017-12-07 | 2018-05-04 | 青岛九远医疗科技有限公司 | One kind nasal obstruction ventilation oil and its preparation method and application |
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- 2020-04-22 CN CN202010321154.6A patent/CN111317756A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107982321A (en) * | 2017-12-07 | 2018-05-04 | 青岛九远医疗科技有限公司 | One kind nasal obstruction ventilation oil and its preparation method and application |
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Application publication date: 20200623 |