CN111280437A - 一种含硒保健品及其应用 - Google Patents
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A—HUMAN NECESSITIES
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Abstract
本发明涉及一种含硒保健组合物及其应用，属于保健食品领域。为了克服目前富硒保健品的保健效果较差，功能疗效不明的技术不足，本发明提供一种含硒保健组合物及其应用，其主要由如下重量份的组分制备得到：甲壳素及其衍生物5份～10份、富硒酵母10份～50份、透明质酸5份～10份、海藻酸盐5份～10份，所述组合物中各组分对于提升免疫力和抗血管氧化具有显著的协同效果，保健作用突出，适合推广应用。
Description
技术领域
本发明涉及一种含硒保健组合物及其应用，属于保健食品领域。
背景技术
富硒食品，就是富含微量元素硒的食品。一般分为天然富硒食品(又称植物活性硒食品)，外源硒富硒食品(也称人工有机硒食品)，比如黑山药、黑芝麻，黑豆，黑花生，黑米、大蒜、加拿大猪肉等都含有硒元素。硒是人体必需的微量元素。硒参与合成人体内多种含硒酶和含硒蛋白。其中谷胱甘肽过氧化物酶，在生物体内催化氢过氧化物或脂质过氧化物转变为水或各种醇类，消除自由基对生物膜的攻击，保护生物膜免受氧化损伤；硒参与构成碘化甲状腺胺酸脱碘酶。硒能提高人体免疫，促进淋巴细胞的增殖及抗体和免疫球蛋白的合成。硒对结肠癌、皮肤癌、肝癌、乳腺癌等多种癌症具有明显的抑制和防护的作用，其在机体内的中间代谢产物甲基烯醇具有较强的抗癌活性。硒与维生素E、大蒜素、亚油酸、锗、锌等营养素具有协同抗氧化的功效，增加抗氧化活性。同时，硒具有减轻和缓解重金属毒性的作用。科学界研究发现，血硒水平的高低与癌的发生息息相关。大量的调查资料说明，一个地区食物和土壤中硒含量的高低与癌症的发病率有直接关系，例如：此地区的食物和土壤中的硒含量高，癌症的发病率和死亡率就低，反之，这个地区的癌症发病率和死亡率就高，事实说明硒与癌症的发生有着密切关系。同时科学界也认识到硒具有预防癌症作用，是人体微量元素的“防癌之王”。美国亚利圣那大学癌症中心Clark教授对1312例癌症患者进行13年对照试验。结果表明每日补硒200μg，癌症死亡率下降50％，癌症总发病率下降37％，其中肺癌下降46％，肠癌下降58％，前列腺癌下降63％。2003年美国食品药品管理局(FDA)明示：“硒能降低患癌风险”和“硒可在人体内产生抗癌变作用”。中国专利申请201610153999.2公开了一种富硒保健品，它所含的活性成分由下列重量份原料配比制备而成：亚硒酸钠2份、金钮扣50份、黄毛岩白菜60份、紫苏梗80份、百蕊草55份，还公开了其具有益气补血作用。
发明内容
发明内容为了克服目前富硒保健品的保健效果较差，功能疗效不明的技术不足，本发明提供一种含硒保健组合物及其应用，其主要由如下重量份的组分制备得到：甲壳素及其衍生物5份～10份、富硒酵母10份～50份、透明质酸5份～10份、海藻酸盐5份～10份，所述组合物中各组分对于提升免疫力和抗血管氧化具有显著的协同效果，保健作用突出，适合推广应用。本发明通过下述技术方案实现上述技术效果：一种含硒保健组合物，其主要由如下重量份的组分制备得到：甲壳素及其衍生物5份～10份、富硒酵母10份～50份、透明质酸5份～10份、海藻酸盐5份～10份。如上所述的含硒保健组合物，所述的甲壳素及其衍生物为壳聚糖、羧甲基壳聚糖、壳聚糖季铵盐、壳寡糖中的一种或多种。如上所述的含硒保健组合物，所述的海藻酸盐为海藻酸钠、海藻酸钙中的一种或两种。所述的富硒酵母可采用常规工艺制备得到或者市售得到，但为了保证本发明保健组合物的保健效果，所述的富硒酵母中硒含量不低于350μg/g，有机硒的比率不低于90％。优选地，含硒保健组合物由如下重量份的组分制备得到：甲壳素及其衍生物7.5份、富硒酵母30份、透明质酸7.5份、海藻酸盐7.5份。如上所述的含硒保健组合物，所述的组合物可以制备成片剂、胶囊、颗粒、饼干或粉剂。其中所述的片剂优选为包衣片或咀嚼片。本发明所述的保健组合物具有提高免疫力，排毒护肝，抗氧化、调节三高的作用。
本发明所述的保健组合物与现有技术相比技术优势在于：1)本发明所述的保健组合物的各种组分具有多种保健用途，其在提高免疫力，排毒护肝，抗氧化、调节三高方面均具有很好的保健价值。2)本发明通过实验证实，保健组合物对免疫低下模型的特异性免疫提高优于市售的富硒保健品，且保健组合物中各组分在提高免疫力方面具有显著的协同作用。
具体实施方式
实施例1一种含硒保健组合物，其主要由如下重量份的组分制备得到：甲壳素及其衍生物5份～10份、富硒酵母10份～50份、透明质酸5份～10份、海藻酸盐5份～10份。按照常规工艺将上述保健组合物制备成片剂、胶囊、颗粒、饼干或粉剂。
实施例2一种含硒保健组合物，其主要由如下重量份的组分制备得到：甲壳素及其衍生物5份～10份、富硒酵母10份～50份、透明质酸5份～10份、海藻酸盐5份～10份。按照常规工艺将上述保健组合物制备成片剂、胶囊、颗粒、饼干或粉剂。
实施例3一种含硒保健组合物，其主要由如下重量份的组分制备得到：甲壳素及其衍生物5份～10份、富硒酵母10份～50份、透明质酸5份～10份、海藻酸盐5份～10份。按照常规工艺将上述保健组合物制备成片剂、胶囊、颗粒、饼干或粉剂。
实施例4一种含硒保健组合物，其主要由如下重量份的组分制备得到：甲壳素及其衍生物5份～10份、富硒酵母10份～50份、透明质酸5份～10份、海藻酸盐5份～10份。按照常规工艺将上述保健组合物制备成片剂、胶囊、颗粒、饼干或粉剂。
实施例5一种含硒保健组合物，其主要由如下重量份的组分制备得到：甲壳素及其衍生物5份～10份、富硒酵母10份～50份、透明质酸5份～10份、海藻酸盐5份～10份。按照常规工艺将上述保健组合物制备成片剂、胶囊、颗粒、饼干或粉剂。
Claims (9)
1.一种含硒保健组合物，其主要由如下重量份的组分制备得到：甲壳素及其衍生物5份～10份、富硒酵母10份～50份、透明质酸5份～10份、海藻酸盐5份～10份。
2.根据权利要求1所述的含硒保健组合物，其特征在于，所述的甲壳素及其衍生物为壳聚糖、羧甲基壳聚糖、壳聚糖季铵盐、壳寡糖中的一种或多种。
3.根据权利要求1所述的含硒保健组合物，其特征在于，所述的海藻酸盐为海藻酸钠、海藻酸钙中的一种或两种。
4.根据权利要求1所述的含硒保健组合物，其特征在于，所述的富硒酵母中硒含量不低于350μg/g，有机硒的比率不低于90％。
5.根据权利要求1所述的含硒保健组合物，其特征在于，含硒保健组合物由如下重量份的组分制备得到：甲壳素及其衍生物7.5份、富硒酵母30份、透明质酸7.5份、海藻酸盐7.5份。
6.根据权利要求1所述的含硒保健组合物，其特征在于，所述的保健组合物为其片剂、胶囊、颗粒、饼干或粉剂。
7.根据权利要求6所述的含硒保健组合物，其特征在于，所述的片剂为包衣片或咀嚼片。
8.权利要求1-7所述的含硒保健组合物在制备提升免疫力保健品中的应用。
9.权利要求1-7所述的含硒保健组合物制备抗血管氧化保健品中的应用。
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