CN111248322A - Polygonatum sibiricum and grapefruit tea and preparation method thereof - Google Patents
Polygonatum sibiricum and grapefruit tea and preparation method thereof Download PDFInfo
- Publication number
- CN111248322A CN111248322A CN202010139526.3A CN202010139526A CN111248322A CN 111248322 A CN111248322 A CN 111248322A CN 202010139526 A CN202010139526 A CN 202010139526A CN 111248322 A CN111248322 A CN 111248322A
- Authority
- CN
- China
- Prior art keywords
- percent
- rhizoma polygonati
- shaddock
- tea
- grapefruit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 240000000560 Citrus x paradisi Species 0.000 title claims abstract description 45
- 241000037831 Polygonatum sibiricum Species 0.000 title claims abstract description 24
- 238000002360 preparation method Methods 0.000 title claims description 15
- 244000269722 Thea sinensis Species 0.000 title abstract 2
- 244000276331 Citrus maxima Species 0.000 claims abstract description 76
- 235000001759 Citrus maxima Nutrition 0.000 claims abstract description 74
- 244000037364 Cinnamomum aromaticum Species 0.000 claims abstract description 23
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 23
- 239000002994 raw material Substances 0.000 claims abstract description 19
- 235000017784 Mespilus germanica Nutrition 0.000 claims abstract description 11
- 244000182216 Mimusops elengi Species 0.000 claims abstract description 11
- 235000000560 Mimusops elengi Nutrition 0.000 claims abstract description 11
- 235000007837 Vangueria infausta Nutrition 0.000 claims abstract description 11
- 240000006766 Cornus mas Species 0.000 claims abstract 4
- 241001122767 Theaceae Species 0.000 claims description 56
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 55
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 54
- 238000001471 micro-filtration Methods 0.000 claims description 35
- 238000000265 homogenisation Methods 0.000 claims description 30
- 239000000706 filtrate Substances 0.000 claims description 27
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 25
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 24
- 235000002639 sodium chloride Nutrition 0.000 claims description 21
- 239000012153 distilled water Substances 0.000 claims description 18
- 239000003480 eluent Substances 0.000 claims description 18
- 238000000605 extraction Methods 0.000 claims description 18
- 238000001914 filtration Methods 0.000 claims description 18
- 238000011282 treatment Methods 0.000 claims description 17
- 238000009835 boiling Methods 0.000 claims description 15
- 235000013399 edible fruits Nutrition 0.000 claims description 15
- 230000001954 sterilising effect Effects 0.000 claims description 14
- 235000015468 Lycium chinense Nutrition 0.000 claims description 13
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 12
- 235000015459 Lycium barbarum Nutrition 0.000 claims description 12
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 12
- 229930006000 Sucrose Natural products 0.000 claims description 12
- 239000004310 lactic acid Substances 0.000 claims description 12
- 235000014655 lactic acid Nutrition 0.000 claims description 12
- 235000010241 potassium sorbate Nutrition 0.000 claims description 12
- 239000004302 potassium sorbate Substances 0.000 claims description 12
- 229940069338 potassium sorbate Drugs 0.000 claims description 12
- 239000011347 resin Substances 0.000 claims description 12
- 229920005989 resin Polymers 0.000 claims description 12
- 150000003839 salts Chemical class 0.000 claims description 12
- 239000011780 sodium chloride Substances 0.000 claims description 12
- 238000001179 sorption measurement Methods 0.000 claims description 12
- 239000005720 sucrose Substances 0.000 claims description 12
- 238000004659 sterilization and disinfection Methods 0.000 claims description 10
- 238000004140 cleaning Methods 0.000 claims description 9
- 238000010828 elution Methods 0.000 claims description 9
- 239000012528 membrane Substances 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 9
- 238000010992 reflux Methods 0.000 claims description 9
- 238000005303 weighing Methods 0.000 claims description 9
- 230000035622 drinking Effects 0.000 claims description 7
- 239000011148 porous material Substances 0.000 claims description 7
- 238000010411 cooking Methods 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 6
- 235000014347 soups Nutrition 0.000 claims description 3
- 244000241838 Lycium barbarum Species 0.000 claims 1
- 235000013616 tea Nutrition 0.000 description 47
- 241000209020 Cornus Species 0.000 description 20
- 244000241872 Lycium chinense Species 0.000 description 12
- 241000700159 Rattus Species 0.000 description 12
- 230000000694 effects Effects 0.000 description 11
- 230000007812 deficiency Effects 0.000 description 10
- 210000003734 kidney Anatomy 0.000 description 10
- 230000002107 myocardial effect Effects 0.000 description 8
- 239000000243 solution Substances 0.000 description 8
- 210000004185 liver Anatomy 0.000 description 7
- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 230000004217 heart function Effects 0.000 description 6
- 208000010125 myocardial infarction Diseases 0.000 description 6
- 210000000952 spleen Anatomy 0.000 description 5
- 235000019640 taste Nutrition 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 230000002861 ventricular Effects 0.000 description 4
- 206010011224 Cough Diseases 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- 210000004351 coronary vessel Anatomy 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 208000002173 dizziness Diseases 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 208000031225 myocardial ischemia Diseases 0.000 description 3
- 208000024172 Cardiovascular disease Diseases 0.000 description 2
- 244000201986 Cassia tora Species 0.000 description 2
- 235000014552 Cassia tora Nutrition 0.000 description 2
- 206010063837 Reperfusion injury Diseases 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 230000004438 eyesight Effects 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 208000028867 ischemia Diseases 0.000 description 2
- 210000003127 knee Anatomy 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 230000008506 pathogenesis Effects 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 239000002504 physiological saline solution Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 230000010410 reperfusion Effects 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 235000019605 sweet taste sensations Nutrition 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 230000035488 systolic blood pressure Effects 0.000 description 2
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 206010008479 Chest Pain Diseases 0.000 description 1
- 241000723347 Cinnamomum Species 0.000 description 1
- 241000142975 Cornaceae Species 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 241000220485 Fabaceae Species 0.000 description 1
- 102000006587 Glutathione peroxidase Human genes 0.000 description 1
- 108700016172 Glutathione peroxidases Proteins 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 108010044467 Isoenzymes Proteins 0.000 description 1
- 241000234280 Liliaceae Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 241000756042 Polygonatum Species 0.000 description 1
- 241000219100 Rhamnaceae Species 0.000 description 1
- 241001093501 Rutaceae Species 0.000 description 1
- 241000208292 Solanaceae Species 0.000 description 1
- 102000019197 Superoxide Dismutase Human genes 0.000 description 1
- 108010012715 Superoxide dismutase Proteins 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- QHMBSVQNZZTUGM-UHFFFAOYSA-N Trans-Cannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1C1C(C(C)=C)CCC(C)=C1 QHMBSVQNZZTUGM-UHFFFAOYSA-N 0.000 description 1
- 102000004987 Troponin T Human genes 0.000 description 1
- 108090001108 Troponin T Proteins 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 208000005946 Xerostomia Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 230000003044 adaptive effect Effects 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 238000010009 beating Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- QHMBSVQNZZTUGM-ZWKOTPCHSA-N cannabidiol Chemical compound OC1=CC(CCCCC)=CC(O)=C1[C@H]1[C@H](C(C)=C)CCC(C)=C1 QHMBSVQNZZTUGM-ZWKOTPCHSA-N 0.000 description 1
- 229950011318 cannabidiol Drugs 0.000 description 1
- ZTGXAWYVTLUPDT-UHFFFAOYSA-N cannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1C1C(C(C)=C)CC=C(C)C1 ZTGXAWYVTLUPDT-UHFFFAOYSA-N 0.000 description 1
- 235000017803 cinnamon Nutrition 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 230000035487 diastolic blood pressure Effects 0.000 description 1
- 230000003205 diastolic effect Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- PCXRACLQFPRCBB-ZWKOTPCHSA-N dihydrocannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1[C@H]1[C@H](C(C)C)CCC(C)=C1 PCXRACLQFPRCBB-ZWKOTPCHSA-N 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 208000017574 dry cough Diseases 0.000 description 1
- 206010013781 dry mouth Diseases 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 235000019990 fruit wine Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 230000000004 hemodynamic effect Effects 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000003680 myocardial damage Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 210000001147 pulmonary artery Anatomy 0.000 description 1
- 235000019633 pungent taste Nutrition 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 230000003867 tiredness Effects 0.000 description 1
- 208000016255 tiredness Diseases 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/34—Tea substitutes, e.g. matè; Extracts or infusions thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/40—Cornaceae (Dogwood family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Abstract
The invention discloses a polygonatum sibiricum and grapefruit tea which is prepared from the following raw materials in percentage by mass: 16.2-72.5% of rhizoma polygonati, 8.1-43.5% of shaddock peel, 1.6-11.6% of dogwood, 1.6-14.5% of cassia seed, 1.6-14.5% of medlar and 1.6-14.5% of red date, wherein the total mass of the components is 100%.
Description
Technical Field
The invention belongs to the technical field of medical health-care products, relates to a polygonatum sibiricum and grapefruit tea and further relates to a preparation method of the polygonatum sibiricum and grapefruit tea.
Background
With the acceleration of the pace of life and the increase of working pressure in modern society, the change of diet rules leads to the gradual increase and the youthful occurrence of cardiovascular diseases, especially the incidence rate of myocardial infarction. In the health food management method published by the Ministry of health in 1996, some Chinese medicinal herbs with dual purposes of medicine and food are allowed to be prepared into health products. Therefore, the use of traditional Chinese medicines in China to prevent cardiovascular diseases and improve the state of sub-health people gradually becomes a research hotspot.
The traditional Chinese medicine classifies the myocardial infarction into the categories of 'obstruction of qi in the chest' and 'palpitation', and the pathogenesis of the myocardial infarction is mainly 'obstruction of qi deficiency, blood stasis and collaterals', which is the syndrome of principal deficiency and secondary excess. Qi deficiency and yin deficiency are the pathological basis of the disease, blood stasis is the principal and the pathogenesis of principal deficiency and secondary excess runs through the whole course of myocardial infarction. Heart qi is the source of power for promoting blood circulation, and abundant heart qi can ensure normal beating rhythm of heart and blood circulation. Qi deficiency can not reach blood vessels and can cause blood stasis. Because qi deficiency causes the body to promote and transform qi, blood stasis will inevitably affect the function of heart governing blood vessels, and further induce myocardial infarction.
Tea therapy is a common conditioning mode in people's life, and the method is simple and convenient, can preserve health and treat diseases, and is deeply loved by people. In recent years, the nutritional effect and the pharmacological effect of the tea are continuously discovered by people, and the health-care function and the disease prevention and treatment effect of the tea are ensured.
Disclosure of Invention
The invention aims to provide polygonatum sibiricum and grapefruit tea which can improve the cardiac function and prevent and protect myocardial cells.
The invention also aims to provide a preparation method of the polygonatum sibiricum grapefruit tea.
The invention adopts the technical scheme that the sealwort grapefruit tea is prepared from the following raw materials in percentage by mass:
16.2 to 72.5 percent of rhizoma polygonati, 8.1 to 43.5 percent of shaddock peel, 1.6 to 11.6 percent of dogwood, 1.6 to 14.5 percent of cassia seed, 1.6 to 14.5 percent of medlar and 1.6 to 14.5 percent of red date, wherein the total mass of the components is 100 percent.
It is preferable that
25.3 to 61.2 percent of rhizoma polygonati, 12.7 to 40.8 percent of shaddock peel, 2.5 to 12.2 percent of dogwood, 2.5 to 16.3 percent of cassia seed, 2.5 to 12.2 percent of medlar and 2.5 to 12.2 percent of red date, wherein the total mass of the components is 100 percent.
The drinking method is directly drinking tea, tea bag or tea soup.
The invention adopts another technical scheme that a preparation method of polygonatum sibiricum and grapefruit tea is specifically carried out according to the following steps:
step 1, weighing each raw material according to the mass percentage, and backing up;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water for boiling, adding salt after boiling, continuing to cook, fishing out the shaddock peel after cooking, and squeezing and dehydrating to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into the dried shaddock peels, putting the dried shaddock peels into water, decocting and filtering to obtain filtrate;
and 5, putting the eluent obtained in the step 2 and the filtrate obtained in the step 3 into a homogenizer, performing primary homogenization treatment, adding auxiliary materials, performing secondary homogenization treatment, performing microfiltration and sterilization to obtain the sealwort grapefruit tea.
In the step 2, during extraction, the mass ratio of rhizoma polygonati to distilled water is 1: 20-25, the extraction temperature is 70-80 ℃, the extraction time is 2-6 h, and during two times of elution, the mass ratio of rhizoma polygonati to ethanol is 1:3 to 5.
In the step 2, the macroporous adsorption resin is any one of ADS-17 or ADS-F8.
In the step 3, the boiling time is 5-8 min, the salt content is 5-10%, the cooking time is 10-15 min, and the water content of the dehydrated shaddock peel is 20-30%.
In the step 4, the mass ratio of the raw materials to the water is 1: 3-8, wherein the decoction temperature is 50-90 ℃, and the decoction time is 2.5-5 h.
In the step 5, the auxiliary materials comprise sucrose, potassium sorbate, lactic acid and sodium chloride, wherein the sucrose accounts for 4-6% of the solution, the potassium sorbate accounts for 0.03-0.05% of the solution, the lactic acid accounts for 0.3-0.75% of the solution, and the sodium chloride accounts for 0.1-0.5% of the solution.
In step 5, the homogenization temperature is 55-65 ℃, the homogenization pressure is 20-25 MPa, the homogenization time is 5-10 min, the aperture of the microfiltration membrane during microfiltration is 0.1-1.0 mu m, the microfiltration pressure is 0.15-0.40 MPa, and the sterilization temperature is 115-120 ℃.
The invention has the beneficial effects that the prepared polygonatum sibiricum and grapefruit tea has reasonable formula, good taste, convenient drinking and suitability for four seasons, and pharmacological tests prove that the raw materials are reasonably matched to achieve the synergistic effect, so that the polygonatum sibiricum and grapefruit tea has the effects of improving the cardiac function and preventing and protecting myocardial cells, and is an ideal health-care beverage.
Drawings
FIG. 1 is the SOD diagram of the sealwort grapefruit tea prepared by the invention;
FIG. 2 is a GSH-Px diagram of the sealwort grapefruit tea prepared by the invention;
FIG. 3 is a CK-MB diagram of a polygonatum sibiricum grapefruit tea prepared according to the present invention;
FIG. 4 is a cTnT diagram of the sealwort grapefruit tea prepared by the invention.
Detailed Description
The present invention will be described in detail below with reference to the accompanying drawings and specific embodiments.
The invention relates to a polygonatum sibiricum and grapefruit tea which is prepared from the following raw materials in percentage by mass:
16.2 to 72.5 percent of rhizoma polygonati, 8.1 to 43.5 percent of shaddock peel, 1.6 to 11.6 percent of dogwood, 1.6 to 14.5 percent of cassia seed, 1.6 to 14.5 percent of medlar and 1.6 to 14.5 percent of red date, wherein the total mass of the components is 100 percent.
It is preferable that
25.3 to 61.2 percent of rhizoma polygonati, 12.7 to 40.8 percent of shaddock peel, 2.5 to 12.2 percent of dogwood, 2.5 to 16.3 percent of cassia seed, 2.5 to 12.2 percent of medlar and 2.5 to 12.2 percent of red date, wherein the total mass of the components is 100 percent.
The drinking method is directly drinking tea, tea bag or tea soup.
A preparation method of polygonatum sibiricum and grapefruit tea specifically comprises the following steps:
step 1, weighing each raw material according to the mass percentage, and backing up;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water for boiling, adding salt after boiling, continuing to cook, fishing out the shaddock peel after cooking, and squeezing and dehydrating to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into the dried shaddock peels, putting the dried shaddock peels into water, decocting and filtering to obtain filtrate;
and 5, putting the eluent obtained in the step 2 and the filtrate obtained in the step 3 into a homogenizer, performing primary homogenization treatment, adding auxiliary materials, performing secondary homogenization treatment, performing microfiltration and sterilization to obtain the sealwort grapefruit tea.
In the step 2, during extraction, the mass ratio of rhizoma polygonati to distilled water is 1: 20-25, the extraction temperature is 70-80 ℃, the extraction time is 2-6 h, and during two times of elution, the mass ratio of rhizoma polygonati to ethanol is 1:3 to 5.
In the step 2, the macroporous adsorption resin is any one of ADS-17 or ADS-F8.
In the step 3, the boiling time is 5-8 min, the salt content is 5-10%, the cooking time is 10-15 min, and the water content of the dehydrated shaddock peel is 20-30%.
In the step 4, the mass ratio of the raw materials to the water is 1: 3-8, wherein the decoction temperature is 50-90 ℃, and the decoction time is 2.5-5 h.
In the step 5, the auxiliary materials comprise sucrose, potassium sorbate, lactic acid and sodium chloride, wherein the sucrose accounts for 4-6% of the solution, the potassium sorbate accounts for 0.03-0.05% of the solution, the lactic acid accounts for 0.3-0.75% of the solution, and the sodium chloride accounts for 0.1-0.5% of the solution.
In step 5, during two homogenization treatments, the homogenization temperature is 55-65 ℃, the homogenization pressure is 20-25 MPa, the homogenization time is 5-10 min, the aperture of the microfiltration membrane during microfiltration is 0.1-1.0 μm, the microfiltration pressure is 0.15-0.40 MPa, and the sterilization temperature is 115-120 ℃.
The functions and the main indications of the raw materials in the traditional Chinese medicine composition are as follows:
rhizoma polygonati: is dried rhizome of Polygonatum sibiricum of Liliaceae, and has mild nature and dry taste, and enters spleen, lung and kidney meridians. Has effects of invigorating qi, nourishing yin, invigorating spleen, moistening lung, and invigorating kidney, and is suitable for treating syndrome of weakness of spleen and stomach, tiredness, debilitation, xerostomia, anorexia, lung deficiency, dry cough, and dizziness, soreness of waist and knees, premature gray hair, internal heat, diabetes, etc. caused by deficiency of kidney essence.
Shaddock peel: is pericarp of Citrus grandis of Rutaceae, with warm nature, pungent, sweet and bitter taste, and enters spleen, lung and kidney meridians. Has the effects of relieving epigastric distention, regulating qi, promoting digestion, reducing phlegm, relieving cough and asthma. It is commonly indicated for qi stagnation, chest distress, abdominal cold pain, food stagnation, diarrhea and dysentery, cough and dyspnea, and Xianqi.
Dogwood fruit: is the mature pulp of dogwood belonging to the family Cornaceae, which is slightly warm in nature, sour and astringent in taste and enters liver and kidney meridians. Has the efficacy of tonifying liver and kidney. It is commonly used for liver and kidney deficiency, dizziness and blurred vision.
Cassia seed: is dry mature seed of Cassia tora or Cassia tora L.of Leguminosae, is slightly cold in nature, bitter, sweet and salty in taste, enters liver, kidney and large intestine channels, and has the effects of clearing liver, improving eyesight, reducing blood fat and lowering blood pressure.
Medlar: is mature fruit of Lycium chinense Mill of Solanaceae. Has mild nature and sweet taste, enters liver and kidney channels, has the effects of improving eyesight, replenishing vital essence and nourishing liver and kidney, and is mainly used for patients with consumptive disease, essence deficiency, soreness of waist and knees, dizziness and tinnitus.
Red dates: is mature fruit of deciduous shrub or small tree of Rhamnaceae. Warm in nature, sweet in taste, and has the effects of invigorating spleen and stomach channels, invigorating spleen-stomach, benefiting qi, nourishing blood, and tranquilizing.
Second, example
Example 1
A preparation method of polygonatum sibiricum and grapefruit tea specifically comprises the following steps:
step 1, weighing 72.5% of rhizoma polygonati, 8.1% of shaddock peel, 10.4% of dogwood, 1.6% of cassia seed, 1.6% of medlar and 5.8% of red date according to the mass for backup;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water to boil for 5min, adding 10% of salt to continuously boil for 10min, fishing out the shaddock peel after boiling, and squeezing and dehydrating until the water content is 30% to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into dried shaddock peels, putting the dried shaddock peels into water, wherein the mass ratio of the raw materials to the water is 1:8, decocting, filtering, and decocting at the temperature of 50 ℃ for 2.5 hours to obtain filtrate;
and 5, putting the eluent obtained in the step 1 and the filtrate obtained in the step 3 into a homogenizer, adding cannabidiol, carrying out primary homogenization treatment, adding 4% of sucrose, 0.04% of potassium sorbate, 0.75% of lactic acid and 0.1% of sodium chloride, carrying out secondary homogenization treatment at 55 ℃, 25MPa for 7min, carrying out microfiltration, wherein the pore diameter of a microfiltration membrane is 1.0 mu m during microfiltration, the microfiltration pressure is 0.15MPa, and carrying out sterilization at 120 ℃ to obtain the sealwort tea.
Example 2
A preparation method of polygonatum sibiricum and grapefruit tea specifically comprises the following steps:
step 1, weighing 61.2% of rhizoma polygonati, 12.7% of shaddock peel, 11.6% of dogwood, 2.5% of cassia seed, 2.5% of medlar and 9.5% of red date for backup;
and 2, crushing rhizoma polygonati, extracting for 6 hours by using distilled water under reflux, wherein the mass ratio of the rhizoma polygonati to the distilled water is 1:20, the extraction temperature is 80 ℃, filtering, separating the filtrate by using ADS-F8 type macroporous adsorption resin, eluting by using 20% ethanol firstly, then 50% ethanol, collecting the eluent, and when the two elutions are carried out, the mass ratio of the rhizoma polygonati to the ethanol is 1: 5;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water to boil for 8min, adding 5% of salt to continue to boil for 15min, fishing out the shaddock peel after boiling, and squeezing and dehydrating until the water content is 20% to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into dried shaddock peels, putting the dried shaddock peels into water, wherein the mass ratio of raw materials to the water is 1:3, decocting, filtering, and decocting at 90 ℃ for 5 hours to obtain filtrate;
and 5, putting the eluent obtained in the step 1 and the filtrate obtained in the step 3 into a homogenizer for primary homogenization treatment, adding 5% of sucrose, 0.05% of potassium sorbate, 0.3% of lactic acid and 0.2% of sodium chloride, performing secondary homogenization treatment at 65 ℃, 24MPa for 5min, carrying out microfiltration, sterilizing at 118 ℃ and obtaining the sealwort and grapefruit tea, wherein the pore diameter of a microfiltration membrane is 0.1 mu m and the microfiltration pressure is 0.40 MPa.
Example 3
A preparation method of polygonatum sibiricum and grapefruit tea specifically comprises the following steps:
step 1, weighing 30.7% of rhizoma polygonati, 43.5% of shaddock peel, 1.6% of dogwood, 16.3% of cassia seed, 6.3% of wolfberry fruit and 1.6% of red date for backup;
and 2, crushing rhizoma polygonati, extracting for 5 hours by using distilled water under reflux, wherein the mass ratio of the rhizoma polygonati to the distilled water is 1:21, the extraction temperature is 75 ℃, filtering, separating the filtrate by using ADS-F8 type macroporous adsorption resin, eluting by using 40% ethanol firstly, then using 70% ethanol, collecting the eluent, and when the two elutions are carried out, the mass ratio of the rhizoma polygonati to the ethanol is 1: 4;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water to boil for 7min, adding 8% of salt to continuously boil for 13min, fishing out the shaddock peel after boiling, and squeezing and dehydrating until the water content is 28% to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into dried shaddock peels, putting the dried shaddock peels into water, wherein the mass ratio of raw materials to the water is 1:5, decocting, filtering, and decocting for 3 hours at the decocting temperature of 60 ℃ to obtain filtrate;
and 5, putting the eluent obtained in the step 1 and the filtrate obtained in the step 3 into a homogenizer for primary homogenization treatment, adding 6% of sucrose, 0.03% of potassium sorbate, 0.5% of lactic acid and 0.5% of sodium chloride, performing secondary homogenization treatment at the homogenization temperature of 60 ℃, the homogenization pressure of 20MPa and the homogenization time of 10min, performing microfiltration, wherein the pore diameter of a microfiltration membrane is 0.22 mu m during microfiltration, the microfiltration pressure is 0.30MPa, and performing sterilization at the sterilization temperature of 115 ℃ to obtain the polygonatum grapefruit tea.
Example 4
A preparation method of polygonatum sibiricum and grapefruit tea specifically comprises the following steps:
step 1, weighing 31.5% of rhizoma polygonati, 15.1% of shaddock peel, 12.2% of dogwood, 14.5% of cassia seed, 14.5% of medlar and 12.2% of red date for backup;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water to boil for 5min, adding 10% of salt to continuously boil for 10min, fishing out the shaddock peel after boiling, and squeezing and dehydrating until the water content is 30% to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into dried shaddock peels, putting the dried shaddock peels into water, wherein the mass ratio of raw materials to the water is 1:6, decocting, filtering, and decocting at the temperature of 50 ℃ for 2.5 hours to obtain filtrate;
and 5, putting the eluent obtained in the step 1 and the filtrate obtained in the step 3 into a homogenizer for first homogenization treatment, adding 4% of sucrose, 0.03% of potassium sorbate, 0.75% of lactic acid and 0.5% of sodium chloride, homogenizing at 57 ℃, homogenizing at 25MPa for 8min, carrying out microfiltration, sterilizing at 120 ℃ and obtaining the sealwort and pomelo tea, wherein the pore diameter of a microfiltration membrane is 0.5 mu m and the microfiltration pressure is 0.15MPa during microfiltration.
Example 5
A preparation method of polygonatum sibiricum and grapefruit tea specifically comprises the following steps:
step 1, weighing 25.3% of rhizoma polygonati, 40.8% of shaddock peel, 2.5% of dogwood, 4.7% of cassia seed, 12.2% of wolfberry fruit and 14.5% of red date for backup;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water to boil for 6min, adding 6% of salt to continue to boil for 10min, fishing out the shaddock peel after boiling, and squeezing and dehydrating until the water content is 20% to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into dried shaddock peels, putting the dried shaddock peels into water, wherein the mass ratio of raw materials to the water is 1:6, decocting, filtering, and decocting for 3 hours at the decocting temperature of 50 ℃ to obtain filtrate;
and 5, putting the eluent obtained in the step 1 and the filtrate obtained in the step 3 into a homogenizer for first homogenization treatment, adding 4% of sucrose, 0.03% of potassium sorbate, 0.75% of lactic acid and 0.5% of sodium chloride, homogenizing at 57 ℃, homogenizing at 25MPa for 8min, carrying out microfiltration, sterilizing at 116 ℃, and thus obtaining the polygonatum-shaddock tea, wherein the pore diameter of a microfiltration membrane is 1.0 mu m during microfiltration, and the microfiltration pressure is 0.15 MPa.
Example 6
A preparation method of polygonatum sibiricum and grapefruit tea specifically comprises the following steps:
step 1, weighing 16.2% of rhizoma polygonati, 41.2% of shaddock peel, 11.6% of dogwood, 16.3% of cassia seed, 12.2% of wolfberry fruit and 2.5% of red date for backup;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water to boil for 8min, adding 7% of salt to continue to boil for 10min, fishing out the shaddock peel after boiling, and squeezing and dehydrating until the water content is 24% to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into dried shaddock peels, putting the dried shaddock peels into water, wherein the mass ratio of raw materials to the water is 1:3, decocting, filtering, and decocting for 5 hours at the decocting temperature of 60 ℃ to obtain filtrate;
and 5, putting the eluent obtained in the step 1 and the filtrate obtained in the step 3 into a homogenizer for first homogenization treatment, adding 5% of sucrose, 0.04% of potassium sorbate, 0.65% of lactic acid and 0.5% of sodium chloride, homogenizing at the temperature of 60 ℃, the homogenization pressure of 20MPa, the homogenization time of 8min, then carrying out microfiltration, wherein the pore diameter of a microfiltration membrane during microfiltration is 1.0 mu m, the microfiltration pressure is 0.40MPa, and sterilizing at the sterilization temperature of 115 ℃ to obtain the sealwort pomelo tea.
Third, clinical experimental data:
1. the test method comprises the following steps:
60 rats were divided into 5 groups of 12 rats each, i.e., sham surgery group, model group, invention group 1, invention group 2, and invention group 3. After 3 days of adaptive feeding, rats freely eat and drink water, each invention group is continuously administrated by gastric lavage for 7 days, the other two groups are administrated with normal saline with equal volume, and each group is administrated once a day. After the seventh day of administration, the patient was connected with an electrocardiogram, intubated with trachea, and connected with an animal respirator. The chest is opened between the 3 rd to 4 th ribs of the left chest to expose the heart. The left anterior descending branch of the coronary artery is punctured and ligated by a suture needle with the left main coronary artery as a mark between the left auricle and the pulmonary artery cone. The successful ligation is determined by observing the indexes of ST-segment elevation of II-lead electrocardiogram and observing the myocardial ischemia such as whitening of tissues below the ligation region with naked eyes. The sham group performed the same procedure except that the coronary artery was not ligated. The ischemia/reperfusion (I/R) model was established by releasing the ligature and reperfusion for 4h 30min after ischemia. Measuring relevant indexes such as hemodynamics, myocardial enzyme and antioxidation.
The sham operation group: only the thread was not ligated, and physiological saline was administered.
Model group: threaded and ligated, and given physiological saline.
Invention group 1: the sealwort grapefruit tea beverage prepared in the application example 1.
Invention group 2: the sealwort grapefruit tea beverage prepared in the application example 2.
Invention group 3: the sealwort grapefruit tea beverage prepared in the application example 3.
2. Test results and conclusions:
2.1 the effect of the sealwort grapefruit tea on the heart function of rats is prevented, after the rat sealwort grapefruit tea is given for 7 days, the heart function of the rats is obviously improved, and the difference has statistical significance, as shown in Table 1.
TABLE 1 comparison of cardiac function indices of the groups of test rats
Note: compared with the group of the pseudo-operation,##P<0.01and#p is less than 0.05; in comparison with the set of models,**p<0.01and*p<0.05,(mean±SD,n=12)。
2.2 the detection results of the antioxidant related indexes of the sealwort grapefruit tea on the myocardial oxidation indexes of rats are shown in the figure 1 and the figure 2: the sealwort grapefruit tea can obviously prevent myocardial ischemia reperfusion injury rat myocardial cell oxidation, obviously improve GSH-Px level and inhibit SOD activity.
2.3 the effect of the sealwort grapefruit tea on rat myocardial enzyme indexes rat myocardial enzyme detection index results are shown in fig. 3 and 4: compared with a model group, the cinnamon fruit wine can obviously reduce the content of CK-MB and cTnT of a rat with myocardial ischemia-reperfusion injury.
In conclusion, the polygonatum sibiricum grapefruit tea can effectively increase the left ventricular systolic pressure LVSP, the left ventricular diastolic end pressure LVEDP, the maximum rising rate (+ dp/dtmax) of the left ventricular systolic pressure and the maximum falling rate (-dp/dtmax) of the left ventricular diastolic pressure, and can effectively improve the cardiac function; compared with the model group, the content of glutathione peroxidase (GSH-Px) and superoxide dismutase SOD in the invention group is more than 6%, and the content of myocardial enzyme creatine kinase isoenzyme CK-MB and troponin T (cTnT) is less than 12%, thus effectively preventing myocardial damage and slowing down the incidence of myocardial infarction.
Claims (10)
1. The sealwort grapefruit tea is characterized by comprising the following raw materials in percentage by mass:
16.2 to 72.5 percent of rhizoma polygonati, 8.1 to 43.5 percent of shaddock peel, 1.6 to 11.6 percent of dogwood, 1.6 to 14.5 percent of cassia seed, 1.6 to 14.5 percent of medlar and 1.6 to 14.5 percent of red date, wherein the total mass of the components is 100 percent.
2. The sealwort grapefruit tea as claimed in claim 1, which is characterized by comprising the following raw materials in percentage by mass:
25.3 to 61.2 percent of rhizoma polygonati, 12.7 to 40.8 percent of shaddock peel, 2.5 to 12.2 percent of dogwood, 2.5 to 16.3 percent of cassia seed, 2.5 to 12.2 percent of medlar and 2.5 to 12.2 percent of red date, wherein the total mass of the components is 100 percent.
3. The sealwort grapefruit tea according to claim 1 or 2, characterized in that the drinking method is direct drinking, tea bag making or tea soup.
4. A method for preparing polygonatum sibiricum grapefruit tea according to claim 1 or 2, which is characterized by comprising the following steps:
step 1, weighing each raw material according to the mass percentage, and backing up;
step 2, crushing rhizoma polygonati, performing reflux extraction by using distilled water, then filtering, separating filtrate by using macroporous adsorption resin, eluting by using 20-40% ethanol, eluting by using 50-70% ethanol, and collecting eluent;
step 3, cleaning the shaddock peel, then putting the shaddock peel into water for boiling, adding salt after boiling, continuing to cook, fishing out the shaddock peel after cooking, and squeezing and dehydrating to obtain dried shaddock peel;
step 4, adding dogwood, cassia seeds, wolfberry fruits and red dates into the dried shaddock peels, putting the dried shaddock peels into water, decocting and filtering to obtain filtrate;
and 5, putting the eluent obtained in the step 2 and the filtrate obtained in the step 3 into a homogenizer, performing primary homogenization treatment, adding auxiliary materials, performing secondary homogenization treatment, performing microfiltration and sterilization to obtain the sealwort grapefruit tea.
5. The preparation method of rhizoma polygonati shaddock tea according to claim 4, wherein in the step 2, during extraction, the mass ratio of rhizoma polygonati to distilled water is 1: 20-25, the extraction temperature is 70-80 ℃, the extraction time is 2-6 h, and during two elutions, the mass ratio of rhizoma polygonati to ethanol is 1:3 to 5.
6. The method for preparing rhizoma polygonati pomelo tea according to claim 4, wherein in the step 2, the macroporous adsorption resin is any one of ADS-17 or ADS-F8.
7. The preparation method of the sealwort grapefruit tea according to claim 4, wherein in the step 3, the boiling time is 5-8 min, the salt content is 5-10%, the cooking time is 10-15 min, and the water content of dehydrated grapefruit peel is 20-30%.
8. The preparation method of rhizoma polygonati shaddock tea according to claim 4, wherein in the step 4, the mass ratio of the raw materials to the water is 1: 3-8, wherein the decoction temperature is 50-90 ℃, and the decoction time is 2.5-5 h.
9. The method for preparing a polygonatum sibiricum shaddock tea according to claim 4, wherein in the step 5, the auxiliary materials are sucrose, potassium sorbate, lactic acid and sodium chloride, wherein the sucrose accounts for 4-6% of the solution, the potassium sorbate accounts for 0.03-0.05% of the solution, the lactic acid accounts for 0.3-0.75% of the solution, and the sodium chloride accounts for 0.1-0.5% of the solution.
10. The method for preparing a polygonatum sibiricum grapefruit tea according to claim 4, wherein in the step 5, the homogenization temperature is 55-65 ℃, the homogenization pressure is 20-25 MPa, the homogenization time is 5-10 min, the pore diameter of a microfiltration membrane during microfiltration is 0.1-1.0 μm, the microfiltration pressure is 0.15-0.40 MPa, and the sterilization temperature is 115-120 ℃.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010139526.3A CN111248322A (en) | 2020-03-03 | 2020-03-03 | Polygonatum sibiricum and grapefruit tea and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010139526.3A CN111248322A (en) | 2020-03-03 | 2020-03-03 | Polygonatum sibiricum and grapefruit tea and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN111248322A true CN111248322A (en) | 2020-06-09 |
Family
ID=70941723
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202010139526.3A Pending CN111248322A (en) | 2020-03-03 | 2020-03-03 | Polygonatum sibiricum and grapefruit tea and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN111248322A (en) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101234171A (en) * | 2008-03-06 | 2008-08-06 | 杨青华 | Health product with blood fat lowering and preventing and treating cardio-cerebralvascular disease function and preparation thereof |
CN103704437A (en) * | 2013-12-19 | 2014-04-09 | 柳州博泽科技有限公司 | Mulberry-leaf pomelo tea and preparation method thereof |
CN103704438A (en) * | 2013-12-19 | 2014-04-09 | 柳州博泽科技有限公司 | Lophatherum pomelo tea and preparation method thereof |
CN106106929A (en) * | 2016-06-28 | 2016-11-16 | 禹州市鼎信中药科技有限公司 | A kind of sealwort medlar filial generation tea prescription and production technology thereof |
CN107880145A (en) * | 2017-12-08 | 2018-04-06 | 大兴安岭林格贝寒带生物科技股份有限公司 | A kind of new method that Siberian solomonseal rhizome polysaccharide is extracted from sealwort |
-
2020
- 2020-03-03 CN CN202010139526.3A patent/CN111248322A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101234171A (en) * | 2008-03-06 | 2008-08-06 | 杨青华 | Health product with blood fat lowering and preventing and treating cardio-cerebralvascular disease function and preparation thereof |
CN103704437A (en) * | 2013-12-19 | 2014-04-09 | 柳州博泽科技有限公司 | Mulberry-leaf pomelo tea and preparation method thereof |
CN103704438A (en) * | 2013-12-19 | 2014-04-09 | 柳州博泽科技有限公司 | Lophatherum pomelo tea and preparation method thereof |
CN106106929A (en) * | 2016-06-28 | 2016-11-16 | 禹州市鼎信中药科技有限公司 | A kind of sealwort medlar filial generation tea prescription and production technology thereof |
CN107880145A (en) * | 2017-12-08 | 2018-04-06 | 大兴安岭林格贝寒带生物科技股份有限公司 | A kind of new method that Siberian solomonseal rhizome polysaccharide is extracted from sealwort |
Non-Patent Citations (2)
Title |
---|
陆茵等: "《中药药理学》", 30 June 2012, 人民卫生出版社 * |
黄世敬: "《冠心病饮食运动宜忌速查手册》", 31 January 2018, 青岛出版社 * |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103960358B (en) | A kind of preparation method of Paeonia suffruticosa yogurt | |
CN106036296A (en) | Health-care beverage capable of reducing blood pressure and making method of health-care beverage | |
CN104783174A (en) | Preparation method of pure natural nutritional, immune and health solid beverage | |
CN104856036A (en) | Health care medicated diet for treating iron-deficiency anemia and preparation method of health care medicated diet | |
CN104082670B (en) | A kind of health-preserving porridge with blood pressure reduction effect and preparation method thereof | |
CN111248322A (en) | Polygonatum sibiricum and grapefruit tea and preparation method thereof | |
CN111870630A (en) | Medicine formula for enhancing resistance and immunity and preparation process | |
CN101869164A (en) | Bulbil skin nourishment tea | |
CN104606571A (en) | Fresh spinach root tea substituted drink with effects of helping produce saliva and slaking thirst and preparation method thereof | |
CN109170052A (en) | A kind of dendrobium nobile stomach-nourishing health tea and preparation method thereof | |
CN103609960A (en) | Nutritive porridge for preventing alopecia and processing technology of nutritive porridge | |
CN113786470B (en) | Traditional Chinese medicine composition for treating deficiency of both qi and blood, food containing traditional Chinese medicine composition and preparation method | |
CN105567530A (en) | Vinegar beverage having blood vessel softening effect and preparation method thereof | |
CN115770268A (en) | Citrus reticulata blanco extract combined preparation for female dysmenorrhea and preparation method thereof | |
CN117244021A (en) | A Chinese medicinal composition extract for reducing blood sugar, blood lipid, blood pressure and uric acid, and its preparation method | |
CN113100367A (en) | Health-care beverage based on traditional Chinese medicine and preparation method thereof | |
CN112210465A (en) | Anise vinegar and brewing process thereof | |
CN115736218A (en) | Tortoise shell blood replenishing suction jelly and preparation method thereof | |
CN110302328A (en) | A kind of Chinese medicine composition of promoting intelligence and strengthening brain and preparation method thereof | |
CN106165791A (en) | A kind of Chinese medicinal drink treating hypertensive heart disease and preparation processing method | |
CN107854528A (en) | A kind of preoperative preparation method for intervening medicine of operations on cranium and brain | |
CN109136044A (en) | A kind of nursing face health wine and preparation method thereof | |
CN106173638A (en) | One receives that kidney is flat rushes Dingchuan beverage and preparation processing method | |
CN106165803A (en) | Fluid-retention in the lung material and preparation processing method are good in a kind of building up the spleen to supplement the lung spleen reinforcing | |
CN106166230A (en) | The medicated tea of a kind of clearing away heat and cooling blood treatment thrombocytopenia and preparation processing method |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200609 |
|
RJ01 | Rejection of invention patent application after publication |