CN111183156A - 用于用抗cd19/cd20免疫治疗来治疗癌症的组合物和方法 - Google Patents

用于用抗cd19/cd20免疫治疗来治疗癌症的组合物和方法 Download PDF

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CN111183156A
CN111183156A CN201880063737.4A CN201880063737A CN111183156A CN 111183156 A CN111183156 A CN 111183156A CN 201880063737 A CN201880063737 A CN 201880063737A CN 111183156 A CN111183156 A CN 111183156A
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car
cell
domain
cells
antigen
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里马斯·J·奥伦塔什
博罗·德罗普利奇
迪娜·施奈德
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Lentigen Technology Inc
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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    • A—HUMAN NECESSITIES
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/41—Vertebrate antigens
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07—ORGANIC CHEMISTRY
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    • C07K2319/00—Fusion polypeptide
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CN201880063737.4A 2017-07-31 2018-07-31 用于用抗cd19/cd20免疫治疗来治疗癌症的组合物和方法 Pending CN111183156A (zh)

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US201762539483P 2017-07-31 2017-07-31
US62/539,483 2017-07-31
PCT/US2018/044654 WO2019028051A1 (en) 2017-07-31 2018-07-31 COMPOSITIONS AND METHODS FOR TREATING CANCER BY ANTI-CD19 / CD20 IMMUNOTHERAPY

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US (3) US10442867B2 (https=)
EP (1) EP3661964A1 (https=)
JP (3) JP7237926B2 (https=)
CN (1) CN111183156A (https=)
AU (2) AU2018309735B2 (https=)
CA (1) CA3071624A1 (https=)
WO (1) WO2019028051A1 (https=)

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CN109423495A (zh) * 2017-08-24 2019-03-05 上海恒润达生生物科技有限公司 一种双靶向嵌合抗原受体及其用途
CN112079934A (zh) * 2019-12-17 2020-12-15 合源生物科技(天津)有限公司 一种靶向cd19的嵌合抗原受体及其用途
CN114685659A (zh) * 2020-12-30 2022-07-01 创新生物有限公司 Cd22特异性人源化抗体及利用其的嵌合抗原受体
WO2025246739A1 (zh) * 2024-05-29 2025-12-04 深圳豪石生物科技有限公司 人源化cd20抗体及其相关产品和应用

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