CN111165802A - 一种用于肾病非透析患者的医用营养粉及制备方法 - Google Patents
一种用于肾病非透析患者的医用营养粉及制备方法 Download PDFInfo
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- CN111165802A CN111165802A CN202010046650.5A CN202010046650A CN111165802A CN 111165802 A CN111165802 A CN 111165802A CN 202010046650 A CN202010046650 A CN 202010046650A CN 111165802 A CN111165802 A CN 111165802A
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Abstract
本发明公开了一种用于肾病非透析患者的医用营养粉及制备方法,涉及医学食品技术领域,包含如下重量份的组份:蛋白质类物质52.5‑420份,脂肪类物质87‑696份、碳水化合物263.5‑2108份、复合矿物质7.95‑63.6份、复合维生素4.17‑33.36份、牛磺酸0.4‑3.2份、单双甘油脂肪酸酯0.5‑4份、核苷酸0.09‑0.7份、左旋肉碱0.06‑0.48份、复合增稠剂9‑72份、香草香精1‑8份、阿斯巴甜0.28‑2.2份;所述的碳水化合物包含麦芽糊精194.5‑1556份、菊粉15‑120份、结晶果糖5‑40份。本发明为低蛋白配方,且所用蛋白均为优质蛋白,乳清蛋白有助于肠道吸收且具有抗氧化的作用,大豆分离蛋白可以减缓肾小球滤过率下降水平、减缓慢性肾病患者的疾病进程。
Description
技术领域
本发明涉及医学食品技术领域,具体为一种用于肾病非透析患者的医用营养粉及制备方法。
背景技术
医用食品全称特殊医学用途配方食品,特殊医学用途配方食品(foods forspecial medical purposes,FSMP)是为了满足进食受限、消化吸收障碍、代谢紊乱或特定疾病状态人群对营养素或膳食的特殊需要,专门加工配制而成的配方食品。该类产品必须在医生或临床营养师指导下,单独食用或与其他食品配合食用。近年来,我国相继出台了《预包装特殊膳食用食品标签》、《特殊医学用途配方食品通则》、《食品安全国家标准特殊医学用途配方食品良好生产规范》、《特殊医学用途配方食品注册管理办法》等几项国家标准,充分说明国家对这项新产业的高度重视。所以,在国家的重视、标准法规逐步完善、行业的共同努力下,特医行业的发展将迎来新的发展。
慢性肾病(chronic kidney disease,CKD)是指肾脏结构、功能或者两者持续异常改变的一种综合征,成为威胁公众健康的重大公共卫生问题。慢性肾病存在患病率高、知晓率低、预后差、医疗费用高等特点。慢性肾病若不能及时治疗,随着时间的推进,肾功能会进一步恶化,进而发展成肾衰竭。慢性肾病患者普遍存在营养不良的症状,会加重患者病情,使患者面临一些并发症,如贫血、心血管疾病、感染、同型半胱氨酸血症等,严重影响患者的生活质量。如何防治代营养不良是慢性肾病治疗的关键环节,营养治疗就是其中最有效的方式。对于肾病非透析患者而言,营养治疗的目的是为了减轻肾脏负担,起到使患者的症状能保持稳定或者减缓疾病进程的作用,所以亟需一种针对于肾病非透析患者的营养粉。
发明内容
本发明的目的在于提供一种用于肾病非透析患者的医用营养粉及制备方法。
为实现上述目的,本发明提供如下技术方案:
一种用于肾病非透析患者的医用营养粉,包含如下重量份的组份:蛋白质类物质52.5-420份,脂肪类物质87-696份、碳水化合物263.5-2108份、复合矿物质7.95-63.6份、复合维生素4.17-33.36份、牛磺酸0.4-3.2份、单双甘油脂肪酸酯0.5-4份、核苷酸0.09-0.7份、左旋肉碱0.06-0.48份、复合增稠剂9-72份、香草香精1-8份、阿斯巴甜0.28-2.2份;所述的碳水化合物包含麦芽糊精194.5-1556份、菊粉15-120份、结晶果糖5-40份。
所述的蛋白质包含乳清蛋白粉22.5-180份、大豆分离蛋白18-144份、全脂奶粉55-440份、牛初乳0.5-4份。
进一步的,所述的脂肪包含紫苏油粉4.35-35份、椰子油粉19-152份、大豆油粉50-400份、橄榄油粉19-152份、中链甘油三酯粉20-400份。
进一步的,所述的复合维生素包含维生素A0.025-0.20份、维生素D30.02-0.16份、维生素E0.045-0.36份、维生素K10.004-0.032份、维生素B10.005-0.04份、维生素B20.005-0.04份、维生素B60.005-0.04份、维生素B120.001-0.008份、L-抗坏血酸钠0.73-5.82份、D-泛酸钙0.015-0.12份、叶酸0.001-0.008份、烟酰胺0.01-0.08份、D-生物素0.0045-0.036份、氯化胆碱2.5-20份、肌醇1.65-13.2份。
进一步的,所述的复合矿物质包括柠檬酸钙4-32份、L-乳酸钙4-32份、磷酸二氢钠2.5-20份、柠檬酸钠7.5-60份、葡萄糖酸镁5-40份、葡萄糖酸亚铁0.2-1.6份、葡萄糖酸锌0.25-2份、葡萄糖酸钾7.5-60份、亚硒酸钠0.0006-0.0046份、碘化钾0.0004-0.0032份、无水硫酸铜0.0125-0.1份、葡萄糖酸锰0.0625-0.5份。
进一步的,所述的复合增稠剂包括卡拉胶3-24份、瓜尔胶3.5-28份、阿拉伯胶2.5-20份。
一种用于肾病非透析患者的医用营养粉的制备方法,包括以下步骤:
(1)准确称量原辅料
预混料a:包括上述的全部蛋白质类物质和部分碳水化合物;
预混料b:包括另一部分碳水化合物和全部复合矿物质;
预混料c:包括上述全部的脂肪类物质、牛磺酸、左旋肉碱、核苷酸、单双甘油脂肪酸酯、香草香精、阿斯巴甜、复配增稠剂;
预混料d:包括剩余的碳水化合物和全部复合维生素;
所述部分碳水化合物为一部分麦芽糊精、菊粉、结晶果糖,所述另一部分碳水化合物为另一部分的麦芽糊精,所述剩余的碳水化合物为剩余的麦芽糊精,三份所述麦芽糊精的比例为1-2:1-2:1-2;
(2)预混料a、b
将预混料a的原辅料转移至槽型混合机进行混合,搅拌时间为50-80min,得到预混料a;将预混料b的原辅料转移至方锥形混合机的混料斗中混合,调节转速为20-30r/min,最高/最低频率为50/5Hz,时间为50-80min,得到预混料b;然后再将预混料a、b投入槽型混合机中,反向搅拌50-80min,取出备用;
(3)制粒
使用高效湿法制粒机制软材,打开搅拌开关,调节转速为20-30r/min,搅拌5-30min;然后向预混料a、b中加入适量40%酒精粘合剂溶液500-1200g,边搅拌边加浆,转速设置采用分段式,先设置搅拌速度为10-30r/min,分散10-20r/min,加入部分酒精,喷加酒精的频率为2-8s/次,每次喷加酒精10-30g,间隔5-10s,加入后搅拌5-15min;其次设置搅拌速度为20-50r/min,分散20-50r/min,再加入部分酒精,加入后搅拌5min;最后加入剩余的酒精,加入后搅拌5-20min,三次添加酒精的比例为2:3:1;
然后取100g样品过40目、80目和100目筛网查看颗粒分布,分布合适即可出料;
(4)干燥整粒
将湿颗粒均匀铺于烘盘中,然后置于60℃烘箱内进行烘干,当品水分至5%左右停止烘干,关闭烘箱开关,取出样品;
(5)预混料c、d
将预混料c的原辅料和预混料d的原辅料投入混料斗中进行预混,设置转速40-80r/min,时间为50-80min,得到预混料c和预混料d;
(6)总混
称取与制粒样品等比例的预混料c、d倒入三维混合机中,再投入制粒样品,设置转速40-80r/min,混合100-150min,得到成品。
与现有技术相比,本发明的有益效果是:本发明为低蛋白配方,且所用蛋白均为优质蛋白,乳清蛋白有助于肠道吸收且具有抗氧化的作用,大豆分离蛋白可以减缓肾小球滤过率下降水平、减缓慢性肾病患者的疾病进程。添加中链甘油三酯,能够实现快速供能。添加多种植物油,富含多不饱和脂肪酸,可以通过调节患者的血压和血脂、抑制炎症反应和抗氧化来改善患者肾脏病理状况,延缓肾功能恶化。富含多种水溶性膳食纤维,可以减少患者肾脏中尿毒症因子的积累,减缓疾病的进程。同时水溶性膳食纤维能够促进益生菌的生长,调节肠道菌群比例,改善肾病患者肠道功能。复合维生素配方,通过不同维生素的协同作用,可以调节患者的免疫力,增强机体抑制炎症的能力,对肾脏起到保护作用。
具体实施方式
下面对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
实施例1:
一种用于肾病非透析患者的医用营养粉,包含如下重量份的组份:蛋白质类物质60份、脂肪类物质100份、碳水化合物300份、复合矿物质10份、复合维生素4.17份、牛磺酸0.4份、单双甘油脂肪酸酯0.5份、核苷酸0.09份、左旋肉碱0.06份、复合增稠剂9份、香草香精1份、阿斯巴甜0.28份;
所述的蛋白质类物质包含乳清蛋白粉45份、大豆分离蛋白38份、全脂奶粉110份、牛初乳0.5份。
所述的脂肪类物质包含紫苏油粉4.35份、椰子油粉19份、大豆油粉50份、橄榄油粉19份、中链甘油三酯粉20份。
所述的碳水化合物包含麦芽糊精194.5份、菊粉15份、结晶果糖5份。
所述的复合维生素包括维生素A0.03份、维生素D30.02份、维生素E0.045份、维生素K10.004份、维生素B10.005份、维生素B20.005份、维生素B60.005份、维生素B120.001份、L-抗坏血酸钠0.73份、D-泛酸钙0.015份、叶酸0.001份、烟酰胺0.01份、D-生物素0.0045份、氯化胆碱2.5份、肌醇1.65份。
所述的复合矿物质包括柠檬酸钙0.5份、L-乳酸钙0.5份、磷酸二氢钠0.5份、柠檬酸钠10份、葡萄糖酸镁12份、葡萄糖酸亚铁0.2份、葡萄糖酸锌0.25份、葡萄糖酸钾10份、亚硒酸钠0.0006份、碘化钾0.0004份、无水硫酸铜0.0125份、葡萄糖酸锰0.0625份。
所述的复合增稠剂包括卡拉胶3份、瓜尔胶3.5份、阿拉伯胶2.5份。
实施例2:
一种用于肾病非透析患者的医用营养粉,包含如下重量份的组份:蛋白质类物质420份、脂肪类物质696份、碳水化合物2108份、复合矿物质63.6份、复合维生素33.36份、牛磺酸3.2份、核苷酸0.72份、单双甘油脂肪酸酯4份、左旋肉碱0.48份、复合增稠剂72份、香草香精8份、阿斯巴甜2.2份;
所述的蛋白质类物质包含乳清蛋白粉180份、大豆分离蛋白144份、全脂奶粉440份、牛初乳4份。
所述的脂肪类物质包含紫苏油粉35份、椰子油粉152份、大豆油粉400份、橄榄油粉152份、中链甘油三酯粉400份。
所述的碳水化合物包含麦芽糊精1556份、菊粉120份、结晶果糖40份。
所述的复合维生素包括维生素A0.20份、维生素D30.16份、维生素E0.36份、维生素K10.032份、维生素B10.04份、维生素B20.04份、维生素B60.04份、维生素B120.008份、L-抗坏血酸钠5.82份、D-泛酸钙0.12份、叶酸0.008份、烟酰胺0.08份、D-生物素0.036份、氯化胆碱20份、肌醇13.2份。
所述的复合矿物质包括柠檬酸钙32份、L-乳酸钙32份、磷酸二氢钠20份、柠檬酸钠60份、葡萄糖酸镁40份、葡萄糖酸亚铁1.6份、葡萄糖酸锌2份、葡萄糖酸钾60份、亚硒酸钠0.0046份、碘化钾0.0032份、无水硫酸铜0.1份、葡萄糖酸锰0.5份。
所述的复合增稠剂包括卡拉胶24份、瓜尔胶28份、阿拉伯胶20份。
实施例3:
一种用于肾病非透析者的医用营养粉,包含如下重量份的组份:蛋白质类物质200份、脂肪类物质350份、碳水化合物1000份、复合矿物质32份、复合维生素18份、牛磺酸1.6份、核苷酸0.35份、左旋肉碱0.24份、复合增稠剂30份、香草香精5份、阿斯巴甜1份。
所述蛋白质类物质包含乳清蛋白粉90份、大豆分离蛋白70份、全脂奶粉200份、牛初乳2.2份。
所述脂肪类物质包含紫苏油粉10份、椰子油粉45份、大豆油粉120份、橄榄油粉45份、中链甘油三酯粉6份。
所述碳水化合物包含麦芽糊精750份、菊粉60份、结晶果糖26份。
复合维生素类物质包括维生素A0.1份、维生素D30.08份、维生素E0.11份、维生素K10.009份、维生素B10.013份、维生素B20.013份、维生素B60.013份、维生素B120.0024份、L-抗坏血酸钠3.75份、D-泛酸钙0.037份、叶酸0.0024份、烟酰胺0.024份、D-生物素0.011份、氯化胆碱10份、肌醇3.9份。
柠檬酸钙10份、L-乳酸钙10份、磷酸二氢钠10份、柠檬酸钠30份、葡萄糖酸镁20份、葡萄糖酸亚铁0.48份、葡萄糖酸锌0.6份、葡萄糖酸钾30份、亚硒酸钠0.0014份、碘化钾0.00096份、无水硫酸铜0.03份、葡萄糖酸锰0.15份。
卡拉胶10份、瓜尔胶12份、阿拉伯胶6份。
实施例4:
根据实施例1中的一种用于肾病非透析患者的医用营养粉的制备方法,包括以下步骤:
(1)准确称量原辅料
预混料a:包括上述的全部蛋白质类物质和部分碳水化合物;
预混料b:包括另一部分碳水化合物和全部复合矿物质;
预混料c:包括上述全部的脂肪类物质、牛磺酸、左旋肉碱、核苷酸、单双甘油脂肪类物质酸酯、香草香精、阿斯巴甜、复配增稠剂;
预混料d:包括剩余的碳水化合物和全部复合维生素;
所述部分碳水化合物为一部分麦芽糊精、菊粉、结晶果糖,所述另一部分碳水化合物为另一部分的麦芽糊精,所述剩余的碳水化合物为剩余的麦芽糊精,三份所述麦芽糊精的比例为1:1:1;
(2)预混料a、b
将预混料a的原辅料转移至槽型混合机进行混合,搅拌时间为50min,得到预混料a;将预混料b的原辅料转移至方锥形混合机的混料斗中混合,调节转速为20r/min,最高/最低频率为50/5Hz,时间为50min,得到预混料b;然后再将预混料a、b投入槽型混合机中,反向搅拌50min,取出备用;
(3)制粒
使用高效湿法制粒机制软材,打开搅拌开关,调节转速为20r/min,搅拌5min;然后向预混料a、b中加入适量40%酒精粘合剂溶液500g,边搅拌边加浆,转速设置采用分段式,先设置搅拌速度为10r/min,分散10r/min,加入部分酒精,喷加酒精的频率为2s/次,每次喷加酒精10g,间隔5s,加入后搅拌5min;其次设置搅拌速度为20r/min,分散20r/min,再加入部分酒精,加入后搅拌5min;最后加入剩余的酒精,加入后搅拌5-20min,三次添加酒精的比例为2:3:1;
然后取100g样品过40目、80目和100目筛网查看颗粒分布,分布合适即可出料;
(4)干燥整粒
将湿颗粒均匀铺于烘盘中,然后置于60℃烘箱内进行烘干,当品水分至5%左右停止烘干,关闭烘箱开关,取出样品;
(5)预混料c、d
将预混料c的原辅料和预混料d的原辅料投入混料斗中进行预混,设置转速40r/min,时间为50min,得到预混料c和预混料d;
(6)总混
称取与制粒样品等比例的预混料c、d倒入三维混合机中,再投入制粒样品,设置转速40r/min,混合100min,得到成品。
实施例5:
结合实施例2中的一种用于肾病非透析患者的医用营养粉的制备方法,包括以下步骤:
(1)准确称量原辅料
预混料a:包括上述的全部蛋白质类物质和部分碳水化合物;
预混料b:包括另一部分碳水化合物和全部复合矿物质;
预混料c:包括上述全部的脂肪类物质、牛磺酸、左旋肉碱、核苷酸、单双甘油脂肪类物质酸酯、香草香精、阿斯巴甜、复配增稠剂;
预混料d:包括剩余的碳水化合物和全部复合维生素;
所述部分碳水化合物为一部分麦芽糊精、菊粉、结晶果糖,所述另一部分碳水化合物为另一部分的麦芽糊精,所述剩余的碳水化合物为剩余的麦芽糊精,三份所述麦芽糊精的比例为1.2:1.5:1.9;
(2)预混料a、b
将预混料a的原辅料转移至槽型混合机进行混合,搅拌时间为80min,得到预混料a;将预混料b的原辅料转移至方锥形混合机的混料斗中混合,调节转速为30r/min,最高/最低频率为50/5Hz,时间为80min,得到预混料b;然后再将预混料a、b投入槽型混合机中,反向搅拌80min,取出备用;
(3)制粒
使用高效湿法制粒机制软材,打开搅拌开关,调节转速为30r/min,搅拌30min;然后向预混料a、b中加入适量40%酒精粘合剂溶液1200g,边搅拌边加浆,转速设置采用分段式,先设置搅拌速度为30r/min,分散20r/min,加入部分酒精,喷加酒精的频率为8s/次,每次喷加酒精30g,间隔10s,加入后搅拌15min;其次设置搅拌速度为50r/min,分散50r/min,再加入部分酒精,加入后搅拌5min;最后加入剩余的酒精,加入后搅拌20min,三次添加酒精的比例为2:3:1;
然后取100g样品过40目、80目和100目筛网查看颗粒分布,分布合适即可出料;
(4)干燥整粒
将湿颗粒均匀铺于烘盘中,然后置于60℃烘箱内进行烘干,当品水分至5%左右停止烘干,关闭烘箱开关,取出样品;
(5)预混料c、d
将预混料c的原辅料和预混料d的原辅料投入混料斗中进行预混,设置转速80r/min,时间为80min,得到预混料c和预混料d;
(6)总混
称取与制粒样品等比例的预混料c、d倒入三维混合机中,再投入制粒样品,设置转速80r/min,混合150min,得到成品。
实施例6:
结合实施例3中的一种用于肾病非透析患者的医用营养粉的制备方法,包括以下步骤:
(1)准确称量原辅料
预混料a:包括上述的全部蛋白质类物质和部分碳水化合物;
预混料b:包括另一部分碳水化合物和全部复合矿物质;
预混料c:包括上述全部的脂肪类物质、牛磺酸、左旋肉碱、核苷酸、单双甘油脂肪类物质酸酯、香草香精、阿斯巴甜、复配增稠剂;
预混料d:包括剩余的碳水化合物和全部复合维生素;
所述部分碳水化合物为一部分麦芽糊精、菊粉、结晶果糖,所述另一部分碳水化合物为另一部分的麦芽糊精,所述剩余的碳水化合物为剩余的麦芽糊精,三份所述麦芽糊精的比例为1.5:1.8:1;
(2)预混料a、b
将预混料a的原辅料转移至槽型混合机进行混合,搅拌时间为50-80min,得到预混料a;将预混料b的原辅料转移至方锥形混合机的混料斗中混合,调节转速为25r/min,最高/最低频率为50/5Hz,时间为55min,得到预混料b;然后再将预混料a、b投入槽型混合机中,反向搅拌75min,取出备用;
(3)制粒
使用高效湿法制粒机制软材,打开搅拌开关,调节转速为20r/min,搅拌10min;然后向预混料a、b中加入适量40%酒精粘合剂溶液1000g,边搅拌边加浆,转速设置采用分段式,先设置搅拌速度为25r/min,分散10r/min,加入部分酒精,喷加酒精的频率为7s/次,每次喷加酒精15g,间隔9s,加入后搅拌13min;其次设置搅拌速度为45r/min,分散35r/min,再加入部分酒精,加入后搅拌5min;最后加入剩余的酒精,加入后搅拌15min,三次添加酒精的比例为2:3:1;
然后取100g样品过40目、80目和100目筛网查看颗粒分布,分布合适即可出料;
(4)干燥整粒
将湿颗粒均匀铺于烘盘中,然后置于60℃烘箱内进行烘干,当品水分至5%左右停止烘干,关闭烘箱开关,取出样品;
(5)预混料c、d
将预混料c的原辅料和预混料d的原辅料投入混料斗中进行预混,设置转速80r/min,时间为55min,得到预混料c和预混料d;
(6)总混
称取与制粒样品等比例的预混料c、d倒入三维混合机中,再投入制粒样品,设置转速40r/min,混合125min,得到成品。
对于本领域技术人员而言,显然本发明不限于上述示范性实施例的细节,而且在不背离本发明的精神或基本特征的情况下,能够以其他的具体形式实现本发明。因此,无论从哪一点来看,均应将实施例看作是示范性的,而且是非限制性的,本发明的范围由所附权利要求而不是上述说明限定,因此旨在将落在权利要求的等同要件的含义和范围内的所有变化囊括在本发明内。
Claims (7)
1.一种用于肾病非透析患者的医用营养粉,其特征在于:包含如下重量份的组份:蛋白质类物质52.5-420份,脂肪类物质87-696份、碳水化合物263.5-2108份、复合矿物质7.95-63.6份、复合维生素4.17-33.36份、牛磺酸0.4-3.2份、单双甘油脂肪酸酯0.5-4份、核苷酸0.09-0.7份、左旋肉碱0.06-0.48份、复合增稠剂9-72份、香草香精1-8份、阿斯巴甜0.28-2.2份;所述的碳水化合物包含麦芽糊精194.5-1556份、菊粉15-120份、结晶果糖5-40份。
2.根据权利要求1所述一种用于肾病非透析患者的医用营养粉,其特征在于:所述的蛋白质包含乳清蛋白粉22.5-180份、大豆分离蛋白18-144份、全脂奶粉55-440份、牛初乳0.5-4份。
3.根据权利要求1所述一种用于肾病非透析患者的医用营养粉,其特征在于:所述的脂肪包含紫苏油粉4.35-35份、椰子油粉19-152份、大豆油粉50-400份、橄榄油粉19-152份、中链甘油三酯粉20-400份。
4.根据权利要求1所述一种用于肾病非透析患者的医用营养粉,其特征在于:所述的复合维生素包含维生素A0.025-0.20份、维生素D30.02-0.16份、维生素E0.045-0.36份、维生素K10.004-0.032份、维生素B10.005-0.04份、维生素B20.005-0.04份、维生素B60.005-0.04份、维生素B120.001-0.008份、L-抗坏血酸钠0.73-5.82份、D-泛酸钙0.015-0.12份、叶酸0.001-0.008份、烟酰胺0.01-0.08份、D-生物素0.0045-0.036份、氯化胆碱2.5-20份、肌醇1.65-13.2份。
5.根据权利要求1所述一种用于肾病非透析患者的医用营养粉,其特征在于:所述的复合矿物质包括柠檬酸钙4-32份、L-乳酸钙4-32份、磷酸二氢钠2.5-20份、柠檬酸钠7.5-60份、葡萄糖酸镁5-40份、葡萄糖酸亚铁0.2-1.6份、葡萄糖酸锌0.25-2份、葡萄糖酸钾7.5-60份、亚硒酸钠0.0006-0.0046份、碘化钾0.0004-0.0032份、无水硫酸铜0.0125-0.1份、葡萄糖酸锰0.0625-0.5份。
6.根据权利要求1所述一种用于肾病非透析患者的医用营养粉,其特征在于:所述的复合增稠剂包括卡拉胶3-24份、瓜尔胶3.5-28份、阿拉伯胶2.5-20份。
7.一种如权利要求1-6中任意一条所述的用于肾病非透析患者的医用营养粉的制备方法,其特征在于:包括以下步骤:
(1)准确称量原辅料
预混料a:包括上述的全部蛋白质类物质和部分碳水化合物;
预混料b:包括另一部分碳水化合物和全部复合矿物质;
预混料c:包括上述全部的脂肪类物质、牛磺酸、左旋肉碱、核苷酸、单双甘油脂肪酸酯、香草香精、阿斯巴甜、复配增稠剂;
预混料d:包括剩余的碳水化合物和全部复合维生素;
所述部分碳水化合物为一部分麦芽糊精、菊粉、结晶果糖,所述另一部分碳水化合物为另一部分的麦芽糊精,所述剩余的碳水化合物为剩余的麦芽糊精,三份所述麦芽糊精的比例为1-2:1-2:1-2;
(2)预混料a、b
将预混料a的原辅料转移至槽型混合机进行混合,搅拌时间为50-80min,得到预混料a;将预混料b的原辅料转移至方锥形混合机的混料斗中混合,调节转速为20-30r/min,最高/最低频率为50/5Hz,时间为50-80min,得到预混料b;然后再将预混料a、b投入槽型混合机中,反向搅拌50-80min,取出备用;
(3)制粒
使用高效湿法制粒机制软材,打开搅拌开关,调节转速为20-30rpm,搅拌5-30min;然后向预混料a、b中加入适量40%酒精粘合剂溶液500-1200g,边搅拌边加浆,转速设置采用分段式,先设置搅拌速度为10-30r/min,分散10-20r/min,加入部分酒精,喷加酒精的频率为2-8s/次,每次喷加酒精10-30g,间隔5-10s,加入后搅拌5-15min;其次设置搅拌速度为20-50r/min,分散20-50r/min,再加入部分酒精,加入后搅拌5min;最后加入剩余的酒精,加入后搅拌5-20min,三次添加酒精的比例为2:3:1;
然后取100g样品过40目、80目和100目筛网查看颗粒分布,分布合适即可出料;
(4)干燥整粒
将湿颗粒均匀铺于烘盘中,然后置于60℃烘箱内进行烘干,当品水分至5%左右停止烘干,关闭烘箱开关,取出样品;
(5)预混料c、d
将预混料c的原辅料、和预混料d的原辅料投入混料斗中进行预混,设置转速40-80r/min,时间为50-80min,得到预混料c和预混料d;
(6)总混
称取与制粒样品等比例的预混料c、d倒入三维混合机中,再投入制粒样品,设置转速40-80r/min,混合100-150min,得到成品。
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CN114868911A (zh) * | 2022-05-19 | 2022-08-09 | 陕西巨子生物技术有限公司 | 一种用于肾病非透析患者的医用营养粉及制备方法 |
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CN114868911A (zh) * | 2022-05-19 | 2022-08-09 | 陕西巨子生物技术有限公司 | 一种用于肾病非透析患者的医用营养粉及制备方法 |
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