CN111163839B - 苯并咪唑酮衍生的bcl6抑制剂 - Google Patents

苯并咪唑酮衍生的bcl6抑制剂 Download PDF

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Publication number
CN111163839B
CN111163839B CN201880047061.XA CN201880047061A CN111163839B CN 111163839 B CN111163839 B CN 111163839B CN 201880047061 A CN201880047061 A CN 201880047061A CN 111163839 B CN111163839 B CN 111163839B
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methyl
amino
chloro
alkyl
hydroxy
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CN111163839A (zh
Inventor
B·R·贝勒妮
M·K·卡特
张桂明
O·A·戴维斯
S·霍尔德
M·G·劳埃德
罗德里格斯 A·瓦雷拉
A·瓦雷拉罗德里格斯
H·伍德沃德
P·诺森蒂
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The Institute of Cancer Research: Royal Cancer Hospital
Cancer Research Technology Ltd
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The Institute of Cancer Research: Royal Cancer Hospital
Cancer Research Technology Ltd
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Priority claimed from GBGB1806130.9A external-priority patent/GB201806130D0/en
Application filed by The Institute of Cancer Research: Royal Cancer Hospital, Cancer Research Technology Ltd filed Critical The Institute of Cancer Research: Royal Cancer Hospital
Priority to CN202410618580.4A priority Critical patent/CN118561812A/zh
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
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  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN201880047061.XA 2017-05-26 2018-05-25 苯并咪唑酮衍生的bcl6抑制剂 Active CN111163839B (zh)

Priority Applications (1)

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CN202410618580.4A CN118561812A (zh) 2017-05-26 2018-05-25 苯并咪唑酮衍生的bcl6抑制剂

Applications Claiming Priority (5)

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GB1708502.8 2017-05-26
GBGB1708502.8A GB201708502D0 (en) 2017-05-26 2017-05-26 Inhibitor compounds
GBGB1806130.9A GB201806130D0 (en) 2018-04-13 2018-04-13 Inhibitor compounds
GB1806130.9 2018-04-13
PCT/GB2018/051447 WO2018215801A1 (en) 2017-05-26 2018-05-25 Benzimidazolone derived inhibitors of bcl6

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CN111163839B true CN111163839B (zh) 2024-05-28

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US (2) US12110286B2 (enExample)
EP (2) EP3630291B9 (enExample)
JP (2) JP7202315B2 (enExample)
KR (2) KR102628675B1 (enExample)
CN (2) CN111163839B (enExample)
AU (2) AU2018274723B2 (enExample)
CA (1) CA3065005A1 (enExample)
ES (1) ES2975690T3 (enExample)
IL (2) IL302300B1 (enExample)
MX (1) MX2023005636A (enExample)
WO (1) WO2018215801A1 (enExample)
ZA (1) ZA202405646B (enExample)

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