CN1111523C - 催化制备取代的联吡啶衍生物的方法 - Google Patents

催化制备取代的联吡啶衍生物的方法 Download PDF

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Publication number
CN1111523C
CN1111523C CN99805552A CN99805552A CN1111523C CN 1111523 C CN1111523 C CN 1111523C CN 99805552 A CN99805552 A CN 99805552A CN 99805552 A CN99805552 A CN 99805552A CN 1111523 C CN1111523 C CN 1111523C
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CN
China
Prior art keywords
alkyl
cation
coo
aryl
phenyl
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Expired - Fee Related
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CN99805552A
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English (en)
Chinese (zh)
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CN1298392A (zh
Inventor
H·盖斯勒
P·格罗斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Celanese Ventures GmbH
Original Assignee
Axiva GmbH
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B37/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
    • C07B37/04—Substitution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/22—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing two or more pyridine rings directly linked together, e.g. bipyridyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Quinoline Compounds (AREA)
CN99805552A 1998-04-29 1999-04-24 催化制备取代的联吡啶衍生物的方法 Expired - Fee Related CN1111523C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19819010.7 1998-04-29
DE19819010 1998-04-29

Publications (2)

Publication Number Publication Date
CN1298392A CN1298392A (zh) 2001-06-06
CN1111523C true CN1111523C (zh) 2003-06-18

Family

ID=7866073

Family Applications (1)

Application Number Title Priority Date Filing Date
CN99805552A Expired - Fee Related CN1111523C (zh) 1998-04-29 1999-04-24 催化制备取代的联吡啶衍生物的方法

Country Status (7)

Country Link
US (1) US6500956B1 (enExample)
EP (1) EP1076648B1 (enExample)
JP (1) JP2002513003A (enExample)
KR (1) KR100592699B1 (enExample)
CN (1) CN1111523C (enExample)
DE (1) DE59913665D1 (enExample)
WO (1) WO1999055675A1 (enExample)

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* Cited by examiner, † Cited by third party
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JP2002105346A (ja) * 2000-07-25 2002-04-10 Fuji Photo Film Co Ltd 金属錯体色素、光電変換素子および光電池
US7319107B2 (en) * 2001-11-08 2008-01-15 Johnson & Johnson Consumer Companies, Inc. 1,2,4-thiadiazolium derivatives as melanocortin receptor modulators
EP1446394B1 (en) 2001-11-08 2006-11-02 Ortho-McNeil Pharmaceutical, Inc. Novel 1,2,4-thiadiazole derivatives as melanocortin receptor modulators
GB0221443D0 (en) 2002-09-16 2002-10-23 Glaxo Group Ltd Pyridine derivates
RU2249476C2 (ru) * 2003-04-22 2005-04-10 Государственное унитарное предприятие научно-исследовательский Институт по повышению нефтеотдачи пластов Академии наук республики Башкортостан Катализатор для получения 2,3-диалкилхинолинов
WO2005073156A1 (ja) * 2004-01-30 2005-08-11 Japan Science And Technology Agency 光学活性ヒドロキシメチル化化合物の製法
JP2005225834A (ja) * 2004-02-16 2005-08-25 Tosoh Corp ２，２’−ビピリジル化合物およびその製造方法
US7767677B2 (en) 2004-09-20 2010-08-03 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
EP2289510A1 (en) 2004-09-20 2011-03-02 Xenon Pharmaceuticals Inc. Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes
EP1799667B1 (en) 2004-09-20 2013-03-20 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as therapeutic agents
EP1804799B1 (en) 2004-09-20 2013-08-21 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
EP2316458A1 (en) 2004-09-20 2011-05-04 Xenon Pharmaceuticals Inc. Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
CA2580856A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
US7951805B2 (en) 2004-09-20 2011-05-31 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase
JP4796776B2 (ja) * 2005-01-28 2011-10-19 広栄化学工業株式会社 ４，４’−ジカルボキシ−２，２’−ビピリジンの製造方法
JP4744163B2 (ja) * 2005-02-28 2011-08-10 広栄化学工業株式会社 ビピリジン類の製造方法
EP2029138A1 (en) 2005-06-03 2009-03-04 Xenon Pharmaceuticals Inc. Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors
BRPI0614262A2 (pt) * 2005-08-02 2011-03-15 Lexicon Pharmaceuticals Inc aril piridinas e métodos para uso das mesmas
SI2278962T1 (sl) 2008-02-21 2014-05-30 Janssen Pharmaceutica N.V. Postopki za zdravljenje dermatoloških motenj
KR20120044287A (ko) * 2009-04-24 2012-05-07 얀센 파마슈티칼즈, 인코포레이티드 1,2,4-티아다이아졸 유도체를 위한 안정적인 국소 조성물
CN103183636A (zh) * 2013-04-05 2013-07-03 浙江大学 一种合成2,2’-联吡啶-4,4’-二甲酸的新方法
CN105481761B (zh) * 2015-11-23 2018-08-31 安徽千和新材料科技发展有限公司 一种2,2’-联吡啶的钯/碳催化制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3804845A (en) * 1971-06-24 1974-04-16 Ici Ltd Manufacture of bipyridyls
US4851538A (en) * 1985-06-14 1989-07-25 Imperial Chemical Industries Plc Polyaromatic compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4814672B1 (enExample) * 1970-02-23 1973-05-09
DE2030562C3 (de) * 1970-06-20 1975-08-07 Daimler-Benz Ag, 7000 Stuttgart Vorrichtung zum Befestigen eines Kommandolautsprechers od.dgl. auf einem Fahrzeugdach
CH674596A5 (enExample) * 1988-02-12 1990-06-15 Sulzer Ag
DE69115688T2 (de) * 1990-04-17 1996-08-14 Ecole Polytech Photovoltaische zellen
WO1994024123A1 (en) * 1993-04-21 1994-10-27 Kodak Limited Ion-sensitive bipyridine complexes
JPH1025342A (ja) * 1996-07-11 1998-01-27 Mitsubishi Heavy Ind Ltd 光機能性重合体組成物及びその製造方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3804845A (en) * 1971-06-24 1974-04-16 Ici Ltd Manufacture of bipyridyls
US4851538A (en) * 1985-06-14 1989-07-25 Imperial Chemical Industries Plc Polyaromatic compounds

Also Published As

Publication number Publication date
JP2002513003A (ja) 2002-05-08
US6500956B1 (en) 2002-12-31
DE59913665D1 (de) 2006-08-24
WO1999055675A1 (de) 1999-11-04
EP1076648A1 (de) 2001-02-21
KR100592699B1 (ko) 2006-06-26
CN1298392A (zh) 2001-06-06
KR20010043122A (ko) 2001-05-25
EP1076648B1 (de) 2006-07-12

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