CN111148763B - 结合于5t4和4-1bb的抗原结合蛋白以及相关组合物和方法 - Google Patents

结合于5t4和4-1bb的抗原结合蛋白以及相关组合物和方法 Download PDF

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CN111148763B
CN111148763B CN201880060362.6A CN201880060362A CN111148763B CN 111148763 B CN111148763 B CN 111148763B CN 201880060362 A CN201880060362 A CN 201880060362A CN 111148763 B CN111148763 B CN 111148763B
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amino acid
seq
acid sequence
polypeptide
binding
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CN111148763A (zh
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大卫·比安弗尼
G·赫尔南德斯-霍约什
琳达·米舍
丹尼尔·米切尔
萨拉·费特列
劳拉·巴拉斯
皮特·伊尔马克
安娜·萨尔
克里斯汀娜·富雷布林
劳拉·冯·尚茨
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Alligator Bioscience AB
Aptevo Research and Development LLC
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Aptevo Research and Development LLC
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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CN201880060362.6A 2017-07-20 2018-07-20 结合于5t4和4-1bb的抗原结合蛋白以及相关组合物和方法 Active CN111148763B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762535107P 2017-07-20 2017-07-20
US62/535,107 2017-07-20
US201762575820P 2017-10-23 2017-10-23
US62/575,820 2017-10-23
US201862648072P 2018-03-26 2018-03-26
US62/648,072 2018-03-26
PCT/EP2018/069850 WO2019016402A1 (en) 2017-07-20 2018-07-20 BINDING PROTEINS BINDING AT 5T4 AND 4-1BB, COMPOSITIONS AND METHODS RELATED THERETO

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CN111148763B true CN111148763B (zh) 2023-11-03

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