CN111132972B - 人sting的小分子调节剂 - Google Patents

人sting的小分子调节剂 Download PDF

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Publication number
CN111132972B
CN111132972B CN201880054141.8A CN201880054141A CN111132972B CN 111132972 B CN111132972 B CN 111132972B CN 201880054141 A CN201880054141 A CN 201880054141A CN 111132972 B CN111132972 B CN 111132972B
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oxo
tetrahydroquinazoline
carboxamide
trifluorobenzyl
dimethyl
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CN111132972A (zh
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蒙纳利·班纳吉
珊蒂普·米蒂雅
萨罗夫·巴素
拉杰普·高希
戴维·普里德
达尔曼德拉·雅德夫
里特斯·什里瓦斯塔瓦
阿尔琼·苏里亚
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Kradev Pharmaceutical Co ltd
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Kradev Pharmaceutical Co ltd
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • C07D239/72—Quinazolines; Hydrogenated quinazolines
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    • C07D471/04—Ortho-condensed systems
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CN201880054141.8A 2017-06-22 2018-06-21 人sting的小分子调节剂 Active CN111132972B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
IN201711021858 2017-06-22
IN201711021858 2017-06-22
GB1709959.9A GB2563642A (en) 2017-06-22 2017-06-22 Small molecule modulators of human STING
GB1709959.9 2017-06-22
IN201811014462 2018-04-16
IN201811014462 2018-04-16
PCT/GB2018/051730 WO2018234808A1 (en) 2017-06-22 2018-06-21 Small molecule modulators of human sting

Publications (2)

Publication Number Publication Date
CN111132972A CN111132972A (zh) 2020-05-08
CN111132972B true CN111132972B (zh) 2024-07-12

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EP (1) EP3642198B1 (enExample)
JP (1) JP7296954B2 (enExample)
KR (1) KR102628892B1 (enExample)
CN (1) CN111132972B (enExample)
AR (1) AR114975A1 (enExample)
AU (1) AU2018288018C1 (enExample)
CA (1) CA3067257A1 (enExample)
CL (1) CL2019003793A1 (enExample)
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WO2019046511A1 (en) 2017-08-31 2019-03-07 Sperovie Biosciences, Inc. COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASE
WO2019051488A1 (en) 2017-09-11 2019-03-14 Sperovie Biosciences, Inc. COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISEASE
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