CN111035001A - Medicine and food homologous selenium-rich health-preserving composition for expelling toxin, beautifying and delaying senescence and preparation method thereof - Google Patents

Medicine and food homologous selenium-rich health-preserving composition for expelling toxin, beautifying and delaying senescence and preparation method thereof Download PDF

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CN111035001A
CN111035001A CN202010018424.6A CN202010018424A CN111035001A CN 111035001 A CN111035001 A CN 111035001A CN 202010018424 A CN202010018424 A CN 202010018424A CN 111035001 A CN111035001 A CN 111035001A
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selenium
beautifying
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food
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颜振清
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L25/00—Food consisting mainly of nutmeat or seeds; Preparation or treatment thereof
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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Abstract

The invention relates to the technical field of health products, in particular to a selenium-rich health-preserving composition with homology of medicine and food for expelling toxin, beautifying and delaying senility and a preparation method thereof, wherein the selenium-rich health-preserving composition is prepared from the following raw materials in parts by weight: 25-35 parts of lycium ruthenicum, 4-8 parts of ginseng, 5-10 parts of walnut kernels, 6-12 parts of sealwort extracts, 5-10 parts of kudzu root extracts, 2-5 parts of selenium-rich malt, 1-4 parts of isomaltitol and 3-6 parts of auxiliary materials, wherein the preparation method comprises the following steps: pulverizing, extracting, concentrating, granulating, drying, grading, and tabletting. According to the invention, the food materials used as both medicine and food are reasonably compatible, so that a synergistic effect is achieved, excessive oxygen free radicals in the body can be eliminated, qi can be regulated, blood can be enriched, metabolism in the body can be promoted, water and collagen growth in the body can be regulated, vivotoxin can be eliminated, the immunity of the body can be enhanced, and the effects of toxin expelling, skin beautifying and aging delaying of the health-care beverage can be enhanced.

Description

Medicine and food homologous selenium-rich health-preserving composition for expelling toxin, beautifying and delaying senescence and preparation method thereof
Technical Field
The invention relates to the technical field of health products, in particular to a selenium-rich health-preserving composition with homology of medicine and food for expelling toxin, beautifying, delaying senility and a preparation method thereof.
Background
In the high-pressure and fast-paced work and life, people have irregular diet, are reluctant to exercise, and have unreasonable diet structure; or after the major disease and the long-term illness, the female suffers from loss of conditioning after the major disease and the long-term illness, and the menstruation, pregnancy, birth and milk of the female consume essence and blood, and the like, and the long-term illness is long, various toxins can be accumulated in the human body, and the symptoms of sallow complexion, lusterless skin, abdominal distension and constipation, chloasma, obesity and the like can be caused, so that various infections can be caused and the toxins overflow to the skin, and the serious diseases such as facial blackness, acne, chloasma, acne, soreness and weakness of waist and lower limbs, pale complexion, fatigue and hypodynamia, palpitation and short breath can be caused, and the serious diseases such as obesity, hyperglycemia, hyperlipidemia, hypertension can be caused, and even myocardial infarction, cerebral. Practice proves that the health and skin beauty of the body can be maintained and the senility can be delayed only by timely removing harmful substances and excessive nutrition in the body and keeping the five internal organs and the body clean.
In order to solve the problem, Chinese patent publication No. CN104054823B provides a toxin-expelling and skin-beautifying dietary therapy composition, which comprises the following components: 8-12 parts of Chinese yam, 3-5 parts of burdock, 16-20 parts of yoghourt and 5-7 parts of lotus leaf powder, wherein the Chinese yam, the burdock, the yoghourt and the lotus leaf powder are effectively combined together, so that the synergistic effect can be achieved, the toxin of internal organs in a body can be effectively eliminated, and meanwhile, the composition has other effects of treating diseases and preserving health, but the composition is simple in proportion, but the effects of expelling toxin and beautifying are not obvious enough.
The Chinese patent publication No. CN103461790B provides a toxin-expelling and beauty-maintaining nutritional powder, which comprises 20% of coix seeds, 20% of red beans, 10% of poria cocos, 10% of ginkgo biloba, 15% of lily, 15% of walnuts and 10% of florists chrysanthemum, and is prepared by the steps of material selection, initial washing, screening, stone removal, fine washing, baking, grinding, detection and the like, but the effects of the Chinese patent only emphasize blood nourishing and kidney tonifying and skin moistening, and the Chinese patent publication No. CN103461790B does not effectively clear heat and toxic materials, promote digestion and eliminate food stagnation, relax bowel and relieve constipation and eliminate free radicals.
The toxin expelling and face nourishing soft capsule is prepared from Chinese medicinal raw materials such as rhubarb, bighead atractylodes rhizome, American ginseng, mirabilite, immature bitter orange, cynanchum otophyllum, radix rubiae yunnanensis, cistanche, lotus leaves and the like, the toxin expelling and face nourishing soft capsule contains rhubarb, the proportion of the rhubarb is high, the rhubarb has the main effects of diminishing inflammation and a certain purgation effect, but the toxin expelling and face nourishing soft capsule cannot be taken for a long time, and the Chinese medicaments are addicted to a certain degree like drugs and generate dependence.
In view of the above, it is necessary to provide a selenium-rich health-preserving composition with homology of medicine and food and a preparation method thereof to solve the problems in the prior art.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide the selenium-enriched health-care composition with homology of medicine and food for expelling toxin, beautifying and delaying senility.
In order to achieve the above object, the present invention provides the following technical solutions:
in a first aspect, the invention provides a selenium-enriched health-preserving composition with homology of medicine and food for expelling toxin, beautifying, delaying senility, which is prepared from the following raw materials in parts by weight: 25-35 parts of black wolfberry, 4-8 parts of ginseng, 5-10 parts of walnut kernel, 6-12 parts of sealwort extract, 5-10 parts of kudzu root extract, 2-5 parts of selenium-rich malt, 1-4 parts of isomaltitol and 3-6 parts of auxiliary materials.
In the further embodiment of the invention, the feed additive is prepared from the following raw materials in parts by weight: 28-32 parts of black wolfberry, 5-7 parts of ginseng, 6-9 parts of walnut kernels, 8-10 parts of sealwort extracts, 6-8 parts of kudzu root extracts, 3-4 parts of selenium-rich malt, 2-3 parts of isomaltitol and 4-5 parts of auxiliary materials.
In the further embodiment of the invention, the feed additive is prepared from the following raw materials in parts by weight: 30 parts of black medlar, 6 parts of ginseng, 7.5 parts of walnut kernel, 9 parts of sealwort extract, 7 parts of kudzu root extract, 3.5 parts of selenium-rich malt, 2.5 parts of isomaltitol and 4.5 parts of auxiliary materials.
In a further embodiment of the present invention, the preparation method of the polygonatum sibiricum extract comprises: extracting naturally dried rhizoma Polygonati twice, with water as extractant, at low temperature of 30-40 deg.C for 15-20min, and at high temperature of 70-80 deg.C for 4-6min, mixing the extracts, centrifuging, removing precipitate, separating juice and residue, and clarifying to obtain rhizoma Polygonati extract.
In a further embodiment of the present invention, the preparation method of the pueraria extract comprises: cleaning radix Puerariae with drinking water, drying, pulverizing into coarse particles, extracting with 70% ethanol 3 times of Gynostemma pentaphyllum for 2 times, 2 hr each time, mixing extractive solutions, concentrating to relative density of 1.20, cooling, drying in rail-type film dryer, pulverizing into fine powder, and sieving with 100 mesh sieve to obtain radix Puerariae extract.
In a further embodiment of the invention, the auxiliary material is dextrin or starch.
In a second aspect, the invention also provides a preparation method of the selenium-enriched health-preserving composition with homology of medicine and food for expelling toxin, beautifying, delaying senility, which comprises the following steps:
s1: pulverizing fructus Lycii, Ginseng radix, and semen Juglandis, and sieving with 60-80 mesh sieve;
s2: weighing crushed lycium ruthenicum, ginseng and walnut kernels, putting the crushed lycium ruthenicum, ginseng and walnut kernels into an extraction kettle, putting 6-8 times of water into the extraction kettle, soaking for 2 hours, decocting for 2 hours, discharging an extracting solution, adding 3-5 times of water into dregs, repeatedly extracting the water for 2 hours, discharging the extracting solution, combining filtrates, filtering the filtrates by a 120-mesh sieve, putting the filtrates into a reduced-pressure concentration kettle, concentrating under reduced pressure until the relative density is 1.3-1.35, and obtaining a concentrated solution;
s3: adding the sealwort extract, the kudzu root extract, the selenium-rich malt and the isomaltitol into the concentrated solution in the step S2, and uniformly stirring to obtain a soft material;
s4: granulating, drying and finishing the soft material obtained in the step (3);
s5: and (4) adding auxiliary materials into the granules obtained after the granulation in the step (4), mixing and tabletting to obtain the selenium-enriched health-preserving composition with the functions of expelling toxin, beautifying, delaying senility and being homologous in medicine and food.
In a further embodiment of the present invention, the vacuum concentration in the vacuum concentration kettle in step S2 is performed under a vacuum degree of-0.05 MPa and at a temperature of 60-70 ℃.
Compared with the prior art, the invention has the following beneficial effects:
(1) according to the invention, the food materials with dual purposes of medicine and food are reasonably compatible, so that a synergistic effect is achieved, excessive oxygen free radicals in a body can be eliminated, qi and blood can be regulated, metabolism in the body can be promoted, water and collagen growth in the body can be regulated, vivotoxin can be eliminated, the immunity of the body can be enhanced, and the effects of detoxifying, beautifying and delaying senescence of the health-care beverage can be enhanced;
(2) the lycium ruthenicum murr used in the invention contains various nutrient elements such as protein, amino acid, vitamin and the like which are beneficial to the human body, contains rich melanocarpine, can effectively remove redundant free radicals in the human body, protects cell tissues of the human body from oxidative damage of the free radicals, and can achieve the effect of delaying senescence, and the effects of expelling toxin, beautifying and delaying senescence can be further improved by matching with ginseng, walnut kernels, sealwort extracts, kudzu root extracts and selenium-rich malt;
(3) the selenium-rich malt used in the invention contains rich trace element selenium, can remove in-vivo garbage and toxin, achieves the purposes of expelling toxin and beautifying, has better antioxidation, can remove excessive free radicals in the body, and has good anti-aging function.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be clearly and completely described below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The selenium-enriched health-preserving composition with the functions of expelling toxin, beautifying, delaying senility and homology of medicine and food comprises the following components: black wolfberry, ginseng, walnut kernel, sealwort extract, kudzu root extract, selenium-rich malt, isomaltitol and auxiliary materials.
The preparation process of the medicine-food homologous selenium-rich health-preserving composition for expelling toxin, beautifying and delaying senility comprises the following steps: crushing → extracting and concentrating → granulating, drying, finishing granules → tabletting, and the medicine and food homologous selenium-rich health preserving composition can be prepared into tablet candy.
The selenium-enriched health-preserving composition with the functions of expelling toxin, beautifying and delaying senility disclosed by the invention comprises the following components in parts by weight:
black wolfberry fruit: the lycium ruthenicum murr is sweet in taste and neutral in nature, is rich in various nutritional ingredients such as protein, lycium ruthenicum polysaccharide, amino acid, vitamins, mineral substances, trace elements and the like, and also contains rich lycium ruthenicum pigment (natural procyanidin, OPC for short), and the OPC can effectively remove redundant free radicals in vivo, protect cell tissues of a human body from being oxidized and damaged by the free radicals and improve the immunity. The grape seed extract is an efficient antioxidant, has an antioxidant effect 30-50 times that of vitamin C and vitamin E, protects collagen, improves skin elasticity and luster, and has the effects of whitening, moisturizing, removing freckles and wrinkles and delaying aging.
Ginseng: ginseng is sweet in taste, slightly bitter, warm in nature and neutral in nature, and enters spleen, lung and heart meridians. It is known as the king of all herbs since ancient times, and has the efficacies of invigorating primordial qi, recovering pulse, relieving depletion, invigorating spleen and lung, strengthening brain and tranquilizing mind, etc. The ginseng contains various saponins, major polysaccharide and minor polysaccharide, which can make the skin white and smooth, enhance the skin elasticity and regenerate the cells, and is an excellent product for skin care and beauty.
Walnut kernel: the walnut kernel has the effects of tonifying deficiency, strengthening body, sterilizing, protecting skin, strengthening brain, resisting aging and the like. The semen Juglandis contains oleum Juglandis, and has effects of nourishing body and enhancing resistance. The walnut kernel is rich in grease, so that the walnut kernel is beneficial to moistening skin and keeping human vitality. Walnut kernel contains more protein, unsaturated fatty acid and phosphoric acid necessary for human nutrition, and has effects of nourishing cell and enhancing brain function. The walnut kernel contains vitamin E, which can prevent cells from oxidative damage of free radicals and has the function of anti-aging.
Rhizoma polygonati: sweet taste, mild nature, nourishing kidney, moistening lung, invigorating spleen and replenishing qi. Contains aspartic acid, digitoxin, anthraquinone compounds, mucilaginous substances, saccharides, nicotinic acid, zinc, copper and iron. Has effects in resisting anoxia, relieving fatigue, resisting aging, enhancing immunity, promoting metabolism, lowering blood sugar, and tonifying heart. Can be used for treating yin deficiency, lung dryness, dry cough, little phlegm, diabetes and polydipsia; weakness of the spleen and stomach, deficiency of spleen qi or spleen yin; kidney deficiency and essence deficiency, soreness and weakness of the waist and knees, early white beard and hair. Has inhibitory effect on typhoid bacillus, Staphylococcus aureus and acid-fast bacillus.
Kudzu root: radix Puerariae has effects of preventing and resisting cancer, caring skin, enlarging breast and caring skin, dilating blood vessel, lowering blood sugar and blood lipid, improving immunity, relieving hangover, lowering blood pressure, and improving intelligence, and radix Puerariae containing radix Puerariae isoflavone has effects of scavenging excessive oxygen free radicals in vivo, caring skin, and delaying aging. Radix Puerariae also has effects of enhancing body resistance, improving skin immunity, stimulating phagocytic function of macrophage M4, removing toxin in vivo, and cleaning blood.
To further illustrate the technical solution of the present invention, the following examples are given.
Example 1:
the selenium-rich health-preserving composition with the functions of expelling toxin, beautifying skin and delaying senility is prepared from the following raw materials in parts by weight: 25 parts of black wolfberry, 4 parts of ginseng, 5 parts of walnut kernel, 6 parts of sealwort extract, 5 parts of kudzu root extract, 2 parts of selenium-rich malt, 1 part of isomaltitol and 3 parts of auxiliary materials.
The preparation method of the polygonatum sibiricum extract comprises the following steps: extracting naturally dried rhizoma Polygonati twice, with water as extractant, at low temperature of 30 deg.C for 15min, and at high temperature of 70 deg.C for 4min, mixing the extracts, centrifuging, removing precipitate, separating juice and residue, and clarifying to obtain rhizoma Polygonati extract.
The preparation method of the kudzu root extract comprises the following steps: cleaning radix Puerariae with drinking water, drying, pulverizing into coarse particles, extracting with 70% ethanol 3 times of Gynostemma pentaphyllum for 2 times, 2 hr each time, mixing extractive solutions, concentrating to relative density of 1.20, cooling, drying in rail-type film dryer, pulverizing into fine powder, and sieving with 100 mesh sieve to obtain radix Puerariae extract.
Wherein the auxiliary material is dextrin.
In addition, the invention also provides a preparation method of the selenium-enriched health-preserving composition with homology of medicine and food for expelling toxin, beautifying, delaying senility, which comprises the following steps:
s1: pulverizing fructus Lycii, Ginseng radix, and semen Juglandis, and sieving with 60-80 mesh sieve;
s2: weighing crushed lycium ruthenicum, ginseng and walnut kernels, putting the crushed lycium ruthenicum, ginseng and walnut kernels into an extraction kettle, putting 6 times of water into the extraction kettle, soaking for 2 hours, decocting for 2 hours, discharging an extracting solution, adding 3 times of water into dregs of a decoction, repeatedly extracting for 2 hours, discharging the extracting solution, combining filtrates, filtering the filtrate by a 120-mesh sieve, putting the filtrate into a reduced-pressure concentration kettle, carrying out reduced-pressure concentration, and concentrating to relative density of 1.3 to obtain a concentrated solution;
s3: adding the sealwort extract, the kudzu root extract, the selenium-rich malt and the isomaltitol into the concentrated solution in the step S2, and uniformly stirring to obtain a soft material;
s4: granulating, drying and finishing the soft material obtained in the step (3);
s5: and (4) adding dextrin into the granules obtained after the granulation in the step (4), mixing and tabletting to obtain the selenium-enriched health-preserving composition with the functions of expelling toxin, beautifying the face and delaying senility.
Wherein the vacuum concentration in the vacuum concentration kettle in the step S2 is carried out under the conditions of vacuum degree of-0.05 MPa and temperature of 60 ℃.
Example 2:
the selenium-rich health-preserving composition with the functions of expelling toxin, beautifying skin and delaying senility is prepared from the following raw materials in parts by weight: 35 parts of black medlar, 8 parts of ginseng, 10 parts of walnut kernel, 12 parts of sealwort extract, 10 parts of kudzu root extract, 5 parts of selenium-rich malt, 4 parts of isomaltitol and 6 parts of auxiliary materials.
The preparation method of the polygonatum sibiricum extract comprises the following steps: extracting naturally dried rhizoma Polygonati twice, with water as extractant, at 40 deg.C for 20min and at 80 deg.C for 6min, mixing the extracts, centrifuging, removing precipitate, separating juice and residue, and clarifying to obtain rhizoma Polygonati extract.
The preparation method of the kudzu root extract comprises the following steps: cleaning radix Puerariae with drinking water, drying, pulverizing into coarse particles, extracting with 70% ethanol 3 times of Gynostemma pentaphyllum for 2 times, 2 hr each time, mixing extractive solutions, concentrating to relative density of 1.20, cooling, drying in rail-type film dryer, pulverizing into fine powder, and sieving with 100 mesh sieve to obtain radix Puerariae extract.
Wherein the auxiliary material is starch.
In addition, the invention also provides a preparation method of the selenium-enriched health-preserving composition with homology of medicine and food for expelling toxin, beautifying, delaying senility, which comprises the following steps:
s1: pulverizing fructus Lycii, Ginseng radix, and semen Juglandis, and sieving with 60-80 mesh sieve;
s2: weighing crushed lycium ruthenicum, ginseng and walnut kernels, putting the crushed lycium ruthenicum, ginseng and walnut kernels into an extraction kettle, putting 8 times of water into the extraction kettle, soaking for 2 hours, decocting for 2 hours, discharging an extracting solution, adding 5 times of water into dregs of a decoction, repeatedly extracting for 2 hours, discharging the extracting solution, combining filtrates, filtering the filtrate by a 120-mesh sieve, putting the filtrate into a reduced-pressure concentration kettle, carrying out reduced-pressure concentration, and concentrating to a relative density of 1.35 to obtain a concentrated solution;
s3: adding the sealwort extract, the kudzu root extract, the selenium-rich malt and the isomaltitol into the concentrated solution in the step S2, and uniformly stirring to obtain a soft material;
s4: granulating, drying and finishing the soft material obtained in the step (3);
s5: and (4) adding starch into the granules obtained after the granulation in the step (4), mixing and tabletting to obtain the medicine-food homologous selenium-rich health-preserving composition for expelling toxin, beautifying and delaying senescence.
Wherein the vacuum concentration in the vacuum concentration kettle in the step S2 is carried out under the vacuum degree of-0.05 MPa and the temperature of 70 ℃.
Example 3:
the selenium-rich health-preserving composition with the functions of expelling toxin, beautifying skin and delaying senility is prepared from the following raw materials in parts by weight: 30 parts of black medlar, 6 parts of ginseng, 7.5 parts of walnut kernel, 9 parts of sealwort extract, 7 parts of kudzu root extract, 3.5 parts of selenium-rich malt, 2.5 parts of isomaltitol and 4.5 parts of auxiliary materials.
The preparation method of the polygonatum sibiricum extract comprises the following steps: extracting naturally dried rhizoma Polygonati twice, with water as extractant, at 40 deg.C for 20min and at 80 deg.C for 6min, mixing the extracts, centrifuging, removing precipitate, separating juice and residue, and clarifying to obtain rhizoma Polygonati extract.
The preparation method of the kudzu root extract comprises the following steps: cleaning radix Puerariae with drinking water, drying, pulverizing into coarse particles, extracting with 70% ethanol 3 times of Gynostemma pentaphyllum for 2 times, 2 hr each time, mixing extractive solutions, concentrating to relative density of 1.20, cooling, drying in rail-type film dryer, pulverizing into fine powder, and sieving with 100 mesh sieve to obtain radix Puerariae extract.
Wherein the auxiliary material is dextrin.
In addition, the invention also provides a preparation method of the selenium-enriched health-preserving composition with homology of medicine and food for expelling toxin, beautifying, delaying senility, which comprises the following steps:
s1: pulverizing fructus Lycii, Ginseng radix, and semen Juglandis, and sieving with 60-80 mesh sieve;
s2: weighing crushed lycium ruthenicum, ginseng and walnut kernels, putting the crushed lycium ruthenicum, ginseng and walnut kernels into an extraction kettle, putting 7 times of water into the extraction kettle, soaking for 2 hours, decocting for 2 hours, discharging an extracting solution, adding 4 times of water into dregs of a decoction, repeatedly extracting for 2 hours, discharging the extracting solution, combining filtrates, filtering the filtrate by a 120-mesh sieve, putting the filtrate into a reduced-pressure concentration kettle, carrying out reduced-pressure concentration, and concentrating to relative density of 1.3 to obtain a concentrated solution;
s3: adding the sealwort extract, the kudzu root extract, the selenium-rich malt and the isomaltitol into the concentrated solution in the step S2, and uniformly stirring to obtain a soft material;
s4: granulating, drying and finishing the soft material obtained in the step (3);
s5: and (4) adding dextrin into the granules obtained after the granulation in the step (4), mixing and tabletting to obtain the selenium-enriched health-preserving composition with the functions of expelling toxin, beautifying the face and delaying senility.
Wherein the vacuum concentration in the vacuum concentration kettle in the step S2 is carried out under the vacuum degree of-0.05 MPa and the temperature of 65 ℃.
Example 4:
the selenium-rich health-preserving composition with the functions of expelling toxin, beautifying skin and delaying senility is prepared from the following raw materials in parts by weight: 28 parts of black wolfberry, 5 parts of ginseng, 7 parts of walnut kernel, 8 parts of sealwort extract, 6 parts of kudzu root extract, 3 parts of selenium-rich malt, 2 parts of isomaltitol and 4 parts of auxiliary materials.
The preparation method of the polygonatum sibiricum extract comprises the following steps: extracting naturally dried rhizoma Polygonati twice, with water as extractant, at low temperature of 33 deg.C for 16min, and at high temperature of 72 deg.C for 4.5min, mixing the extracts, centrifuging, removing precipitate, separating juice and residue, and clarifying to obtain rhizoma Polygonati extract.
The preparation method of the kudzu root extract comprises the following steps: cleaning radix Puerariae with drinking water, drying, pulverizing into coarse particles, extracting with 70% ethanol 3 times of Gynostemma pentaphyllum for 2 times, 2 hr each time, mixing extractive solutions, concentrating to relative density of 1.20, cooling, drying in rail-type film dryer, pulverizing into fine powder, and sieving with 100 mesh sieve to obtain radix Puerariae extract.
Wherein the auxiliary material is starch.
In addition, the invention also provides a preparation method of the selenium-enriched health-preserving composition with homology of medicine and food for expelling toxin, beautifying, delaying senility, which comprises the following steps:
s1: pulverizing fructus Lycii, Ginseng radix, and semen Juglandis, and sieving with 60-80 mesh sieve;
s2: weighing crushed lycium ruthenicum, ginseng and walnut kernels, putting the crushed lycium ruthenicum, ginseng and walnut kernels into an extraction kettle, putting 6.5 times of water into the extraction kettle, soaking for 2 hours, decocting for 2 hours, discharging an extracting solution, adding 3.5 times of water into dregs, repeatedly extracting the water for 2 hours, discharging the extracting solution, combining the filtrates, filtering the filtrates by a 120-mesh sieve, putting the filtrates into a reduced-pressure concentration kettle, concentrating under reduced pressure until the relative density is 1.35, and obtaining a concentrated solution;
s3: adding the sealwort extract, the kudzu root extract, the selenium-rich malt and the isomaltitol into the concentrated solution in the step S2, and uniformly stirring to obtain a soft material;
s4: granulating, drying and finishing the soft material obtained in the step (3);
s5: and (4) adding starch into the granules obtained after the granulation in the step (4), mixing and tabletting to obtain the medicine-food homologous selenium-rich health-preserving composition for expelling toxin, beautifying and delaying senescence.
Wherein the vacuum concentration in the vacuum concentration kettle in the step S2 is carried out under the conditions of vacuum degree of-0.05 MPa and temperature of 63 ℃.
Example 5:
the selenium-rich health-preserving composition with the functions of expelling toxin, beautifying skin and delaying senility is prepared from the following raw materials in parts by weight: 32 parts of black wolfberry, 7 parts of ginseng, 9 parts of walnut kernel, 10 parts of sealwort extract, 9 parts of kudzu root extract, 4 parts of selenium-rich malt, 3 parts of isomaltitol and 5 parts of auxiliary materials.
The preparation method of the polygonatum sibiricum extract comprises the following steps: extracting naturally dried rhizoma Polygonati twice, with water as extractant, at 38 deg.C for 19min and at 78 deg.C for 5.5min, mixing the extracts, centrifuging, removing precipitate, separating juice and residue, and clarifying to obtain rhizoma Polygonati extract.
The preparation method of the kudzu root extract comprises the following steps: cleaning radix Puerariae with drinking water, drying, pulverizing into coarse particles, extracting with 70% ethanol 3 times of Gynostemma pentaphyllum for 2 times, 2 hr each time, mixing extractive solutions, concentrating to relative density of 1.20, cooling, drying in rail-type film dryer, pulverizing into fine powder, and sieving with 100 mesh sieve to obtain radix Puerariae extract.
Wherein the auxiliary material is dextrin.
In addition, the invention also provides a preparation method of the selenium-enriched health-preserving composition with homology of medicine and food for expelling toxin, beautifying, delaying senility, which comprises the following steps:
s1: pulverizing fructus Lycii, Ginseng radix, and semen Juglandis, and sieving with 60-80 mesh sieve;
s2: weighing crushed lycium ruthenicum, ginseng and walnut kernels, putting the crushed lycium ruthenicum, ginseng and walnut kernels into an extraction kettle, putting 7.5 times of water into the extraction kettle, soaking for 2 hours, decocting for 2 hours, discharging an extracting solution, adding 4.5 times of water into dregs, repeatedly extracting the water for 2 hours, discharging the extracting solution, combining the filtrates, filtering the filtrates by a 120-mesh sieve, putting the filtrates into a reduced-pressure concentration kettle, concentrating under reduced pressure until the relative density is 1.3, and obtaining a concentrated solution;
s3: adding the sealwort extract, the kudzu root extract, the selenium-rich malt and the isomaltitol into the concentrated solution in the step S2, and uniformly stirring to obtain a soft material;
s4: granulating, drying and finishing the soft material obtained in the step (3);
s5: and (4) adding dextrin into the granules obtained after the granulation in the step (4), mixing and tabletting to obtain the selenium-enriched health-preserving composition with the functions of expelling toxin, beautifying the face and delaying senility.
Wherein the vacuum concentration in the vacuum concentration kettle in the step S2 is carried out under the conditions of vacuum degree of-0.05 MPa and temperature of 68 ℃.
Test example:
clinical tests are carried out on the pills prepared in the embodiments 1-5 of the invention, 200 people with constipation and mild acne are selected in total, the pills are divided into 5 groups on average, 40 people in each group have no significant difference in age.
The test method comprises the following steps: the pills prepared in examples 1 to 5 were taken daily for 1 hour after breakfast and supper for 1 to 5 groups of patients, and the results were observed after continuous drinking for 40 days.
Evaluation criteria:
obviously improve the following steps: the clinical symptoms such as constipation, acne and the like disappear mostly or basically, the skin is bright and glossy, and the spirit state is good;
and (3) relieving: the clinical symptoms such as constipation, acne and the like are obviously relieved, the skin gradually becomes smooth and bright, and the mental state is better;
and (4) invalidation: constipation, acne and other clinical symptoms have no obvious change, the skin color has no obvious change, and the mental state is worse.
The specific test results are shown in the following table:
group of Number of cases Obvious improvement example Example of alleviation Examples of invalidity The total effective rate%
Example 1 40 30 9 1 97.5
Example 2 40 32 7 1 97.5
Example 3 40 33 7 0 100
Example 4 40 31 9 0 100
Example 5 40 32 7 1 97.5
The experimental results show that the pills prepared by the embodiment of the invention have very excellent treatment and regulation effects on constipation and acne, the total effective rate is more than 97.5%, and the components have synergistic effects, so that excessive oxygen free radicals in vivo can be eliminated, qi can be regulated, blood can be enriched, metabolism in vivo can be promoted, water and collagen growth in vivo can be regulated, vivotoxin can be eliminated, the organism immunity can be enhanced, and the effects of detoxifying, beautifying and delaying senescence of the health-care beverage can be enhanced.
In conclusion, the innovate points of the medicine-food homologous selenium-rich health-preserving composition for expelling toxin, beautifying, delaying senility are as follows:
1. according to the invention, the food materials with dual purposes of medicine and food are reasonably compatible, so that a synergistic effect is achieved, excessive oxygen free radicals in a body can be eliminated, qi and blood can be regulated, metabolism in the body can be promoted, water and collagen growth in the body can be regulated, vivotoxin can be eliminated, the immunity of the body can be enhanced, and the effects of detoxifying, beautifying and delaying senescence of the health-care beverage can be enhanced;
2. the lycium ruthenicum murr used in the invention contains various nutrient elements such as protein, amino acid, vitamin and the like which are beneficial to the human body, contains rich melanocarpine, can effectively remove redundant free radicals in the human body, protects cell tissues of the human body from oxidative damage of the free radicals, and can achieve the effect of delaying senescence, and the effects of expelling toxin, beautifying and delaying senescence can be further improved by matching with ginseng, walnut kernels, sealwort extracts, kudzu root extracts and selenium-rich malt;
3. the selenium-rich malt used in the invention contains rich trace element selenium, can remove in-vivo garbage and toxin, achieves the purposes of expelling toxin and beautifying, has better antioxidation, can remove excessive free radicals in the body, and has good anti-aging function.
The above description is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiments, and all technical solutions belonging to the idea of the present invention belong to the protection scope of the present invention. It should be noted that modifications and embellishments within the scope of the invention may occur to those skilled in the art without departing from the principle of the invention, and are considered to be within the scope of the invention.

Claims (8)

1. The selenium-enriched health-preserving composition with homology of medicine and food for expelling toxin, beautifying and delaying senility is characterized by being prepared from the following raw materials in parts by weight: 25-35 parts of black wolfberry, 4-8 parts of ginseng, 5-10 parts of walnut kernel, 6-12 parts of sealwort extract, 5-10 parts of kudzu root extract, 2-5 parts of selenium-rich malt, 1-4 parts of isomaltitol and 3-6 parts of auxiliary materials.
2. The selenium-enriched health-preserving composition with homology of medicine and food for expelling toxin, beautifying skin and delaying senility as claimed in claim 1, which is prepared from the following raw materials in parts by weight: 28-32 parts of black wolfberry, 5-7 parts of ginseng, 6-9 parts of walnut kernels, 8-10 parts of sealwort extracts, 6-8 parts of kudzu root extracts, 3-4 parts of selenium-rich malt, 2-3 parts of isomaltitol and 4-5 parts of auxiliary materials.
3. The pill for expelling toxin, beautifying, removing acnes and removing spots according to claim 1 is characterized by being prepared from the following raw materials in parts by weight: 30 parts of black medlar, 6 parts of ginseng, 7.5 parts of walnut kernel, 9 parts of sealwort extract, 7 parts of kudzu root extract, 3.5 parts of selenium-rich malt, 2.5 parts of isomaltitol and 4.5 parts of auxiliary materials.
4. The selenium-enriched health-preserving composition with functions of detoxification, beauty treatment and senescence delaying according to claim 1, wherein the preparation method of the polygonatum sibiricum extract comprises the following steps: extracting naturally dried rhizoma Polygonati twice, with water as extractant, at low temperature of 30-40 deg.C for 15-20min, and at high temperature of 70-80 deg.C for 4-6min, mixing the extracts, centrifuging, removing precipitate, separating juice and residue, and clarifying to obtain rhizoma Polygonati extract.
5. The selenium-enriched health-preserving composition with the functions of expelling toxin, beautifying skin and delaying senility as claimed in claim 1, wherein the preparation method of the kudzu root extract comprises the following steps: cleaning radix Puerariae with drinking water, drying, pulverizing into coarse particles, extracting with 70% ethanol 3 times of Gynostemma pentaphyllum for 2 times, 2 hr each time, mixing extractive solutions, concentrating to relative density of 1.20, cooling, drying in rail-type film dryer, pulverizing into fine powder, and sieving with 100 mesh sieve to obtain radix Puerariae extract.
6. The selenium-enriched health-preserving composition with homology of medicine and food for expelling toxin, beautifying skin and delaying senility as claimed in claim 1, wherein the auxiliary material is dextrin or starch.
7. The preparation method of the selenium-enriched health-preserving composition with homology of medicine and food for expelling toxin, beautifying skin and delaying senility as claimed in any one of claims 1 to 6, which is characterized by comprising the following steps:
s1: pulverizing fructus Lycii, Ginseng radix, and semen Juglandis, and sieving with 60-80 mesh sieve;
s2: weighing crushed lycium ruthenicum, ginseng and walnut kernels, putting the crushed lycium ruthenicum, ginseng and walnut kernels into an extraction kettle, putting 6-8 times of water into the extraction kettle, soaking for 2 hours, decocting for 2 hours, discharging an extracting solution, adding 3-5 times of water into dregs, repeatedly extracting the water for 2 hours, discharging the extracting solution, combining filtrates, filtering the filtrates by a 120-mesh sieve, putting the filtrates into a reduced-pressure concentration kettle, concentrating under reduced pressure until the relative density is 1.3-1.35, and obtaining a concentrated solution;
s3: adding the sealwort extract, the kudzu root extract, the selenium-rich malt and the isomaltitol into the concentrated solution in the step S2, and uniformly stirring to obtain a soft material;
s4: granulating, drying and finishing the soft material obtained in the step (3);
s5: and (4) adding auxiliary materials into the granules obtained after the granulation in the step (4), mixing and tabletting to obtain the selenium-enriched health-preserving composition with the functions of expelling toxin, beautifying, delaying senility and being homologous in medicine and food.
8. The preparation method of the selenium-enriched health preserving composition with homology of medicine and food for detoxifying, beautifying, delaying aging according to claim 7, wherein the conditions of the vacuum concentration in the vacuum concentration kettle in the step S2 are vacuum degree of-0.05 MPa and temperature of 60-70 ℃.
CN202010018424.6A 2020-01-08 2020-01-08 Medicine and food homologous selenium-rich health-preserving composition for expelling toxin, beautifying and delaying senescence and preparation method thereof Pending CN111035001A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111357907A (en) * 2020-03-10 2020-07-03 武汉有明汉方医药科技有限责任公司 Health food for maintaining beauty and keeping young and preparation method thereof
CN115812886A (en) * 2022-12-30 2023-03-21 恩施硒禾生物科技有限公司 Medicinal and edible selenium-rich composite solid beverage and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN1142924A (en) * 1995-05-11 1997-02-19 毕长宏 Health drink
CN109223899A (en) * 2018-11-02 2019-01-18 无锡华粹堂健康管理有限公司 One seed ginseng Shen supports precious soup of member four and preparation method thereof
CN110477312A (en) * 2019-08-08 2019-11-22 新疆南京同仁堂健康药业有限公司 Black fruit fructus lycii joins smart piece and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1142924A (en) * 1995-05-11 1997-02-19 毕长宏 Health drink
CN109223899A (en) * 2018-11-02 2019-01-18 无锡华粹堂健康管理有限公司 One seed ginseng Shen supports precious soup of member four and preparation method thereof
CN110477312A (en) * 2019-08-08 2019-11-22 新疆南京同仁堂健康药业有限公司 Black fruit fructus lycii joins smart piece and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111357907A (en) * 2020-03-10 2020-07-03 武汉有明汉方医药科技有限责任公司 Health food for maintaining beauty and keeping young and preparation method thereof
CN115812886A (en) * 2022-12-30 2023-03-21 恩施硒禾生物科技有限公司 Medicinal and edible selenium-rich composite solid beverage and preparation method thereof

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Application publication date: 20200421