CN111000964A - Medicine for treating abdominal pain and diarrhea and preparation method thereof - Google Patents
Medicine for treating abdominal pain and diarrhea and preparation method thereof Download PDFInfo
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- CN111000964A CN111000964A CN201911062030.4A CN201911062030A CN111000964A CN 111000964 A CN111000964 A CN 111000964A CN 201911062030 A CN201911062030 A CN 201911062030A CN 111000964 A CN111000964 A CN 111000964A
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- 239000003814 drug Substances 0.000 title claims abstract description 69
- 206010012735 Diarrhoea Diseases 0.000 title claims abstract description 44
- 208000004998 Abdominal Pain Diseases 0.000 title claims abstract description 36
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 229940079593 drug Drugs 0.000 title claims description 5
- 239000007788 liquid Substances 0.000 claims abstract description 32
- 241000628997 Flos Species 0.000 claims abstract 3
- 244000223760 Cinnamomum zeylanicum Species 0.000 claims description 33
- 235000017803 cinnamon Nutrition 0.000 claims description 33
- 235000006886 Zingiber officinale Nutrition 0.000 claims description 9
- 235000008397 ginger Nutrition 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 244000223014 Syzygium aromaticum Species 0.000 claims description 7
- 235000016639 Syzygium aromaticum Nutrition 0.000 claims description 7
- 238000001914 filtration Methods 0.000 claims description 7
- 244000062241 Kaempferia galanga Species 0.000 claims description 6
- 235000013421 Kaempferia galanga Nutrition 0.000 claims description 6
- 238000009835 boiling Methods 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 4
- 238000002791 soaking Methods 0.000 claims description 4
- 238000010438 heat treatment Methods 0.000 claims description 3
- 244000273928 Zingiber officinale Species 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 208000002193 Pain Diseases 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 8
- 210000001015 abdomen Anatomy 0.000 abstract description 5
- 239000000463 material Substances 0.000 abstract description 3
- 210000002784 stomach Anatomy 0.000 abstract description 3
- 238000010521 absorption reaction Methods 0.000 abstract description 2
- 230000002411 adverse Effects 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 206010000060 Abdominal distension Diseases 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 210000000936 intestine Anatomy 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 210000004916 vomit Anatomy 0.000 abstract 1
- 230000008673 vomiting Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 description 12
- 241000234314 Zingiber Species 0.000 description 8
- 235000008534 Capsicum annuum var annuum Nutrition 0.000 description 2
- 235000019510 Long pepper Nutrition 0.000 description 2
- 240000003455 Piper longum Species 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 244000141218 Alpinia officinarum Species 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 229940124599 anti-inflammatory drug Drugs 0.000 description 1
- 235000021270 cold food Nutrition 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 231100000956 nontoxicity Toxicity 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
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Abstract
The invention discloses a medicinal formula for treating abdominal pain and diarrhea and a preparation method thereof, which utilize the pungent and hot functions of traditional Chinese medicines to expel gastrointestinal cold evil and can be used for treating all people such as infants, children, adults and the like. The medicine is prepared from cortex Cinnamomi as main material, and is prepared by mixing with one or two of Zingiberis rhizoma, rhizoma Alpiniae Officinarum, fructus Piperis Longi, fructus Litseae, flos Caryophylli, etc. with high quality and no adverse side effects to obtain four formulas with the same function and different proportions; after being decocted with slow fire to prepare the liquid medicine, the liquid medicine is wiped on the navel and the whole abdomen of a patient, and can achieve the purposes of quickly relieving pain, stopping diarrhea and recovering the normal functions of intestines and stomach through the absorption of the skin. The medicine for treating abdominal pain and diarrhea has good effects of quickly stopping diarrhea, relieving pain, stopping vomit and relieving abdominal distension; meanwhile, the medicine for treating the bellyache and the diarrhea has the advantages of convenient use, safety and no toxic or side effect, and can be widely used for treating the bellyache and the diarrhea of infants, children and adults. The medicine for treating abdominal pain and diarrhea has the advantages of convenient processing and extremely low cost.
Description
Technical Field
The invention belongs to the technical field of Chinese patent medicines, and particularly relates to a Chinese medicinal composition for treating abdominal pain and diarrhea of infants, children and even adults by preparing two or three of cinnamon, dried ginger, galangal, long pepper, fructus piperis longi, clove and other medicines into a prescription, then decocting, filtering, distilling and the like to prepare a liquid medicine, and rubbing the liquid medicine on the abdomen of a patient.
Background
The abdominal pain and diarrhea are common diseases of infants and adults, and the treatment is mostly carried out by adopting a method of oral administration or injection of anti-inflammatory drugs at present. Although the treatment mode is effective and rapid, the side effect of the medicine is large, and adverse effects are brought to the body.
The existing traditional Chinese medicine oral preparations for infants on the market have relatively thick traditional Chinese medicine flavor, so that the infants are difficult to take medicine; the navel-applied medicine plaster has the advantages of small skin acting area, less medicine absorption effect, slow action, difficult quick action, long cure period, no quick control of abdominal pain and diarrhea, and patients suffering from pain and suffering from decoction.
The medicine is convenient to use, can quickly treat abdominal pain and diarrhea, achieves the aims of quickly stopping diarrhea and relieving pain, and effectively reduces the pain of patients.
Disclosure of Invention
The invention aims to prepare the medicine for treating the abdominal pain and the diarrhea, which has no toxic or side effect, simple and convenient use, quick response and low cost, can quickly and conveniently treat the abdominal pain and the diarrhea pain of infants and even adults, and reduces the pain of patients.
The medicine of the invention has simple processing technology and convenient preparation.
The invention adopts the technical scheme that the medicine for treating abdominal pain and diarrhea is composed of two or three of cinnamon, dried ginger, galangal, fructus piperis longi, fructus piperis cubeba, clove and the like.
The first formula of the medicine for treating abdominal pain and diarrhea is 45g of cinnamon and 55g of dried ginger; the second formula comprises 45g of cinnamon and 55g of galangal; the third prescription is 45g of cinnamon and 55g of fructus piperis longi; the fourth prescription is 45g of cinnamon, 45g of fructus piperis longi and 10g of clove.
According to the formula I, the formula II, the formula III and the formula IV, cinnamon, dried ginger, lesser galangal rhizome, long pepper, fructus piperis longi and clove are respectively placed in water according to the formula amount for soaking for 6 hours, then the soaked cinnamon is heated to boil, then the cinnamon is decocted for 10 minutes by slow fire, the soaked other medicinal materials are added into the cinnamon liquid medicine, the cinnamon liquid medicine is heated to boil, then the cinnamon liquid medicine is continuously decocted for 40 minutes by slow fire, then the cinnamon liquid medicine is dried to normal temperature, and the cinnamon liquid medicine is placed for 7 days after being filtered, so that the medicine for treating abdominal pain and diarrhea can be obtained.
The first, second, third and fourth formulas are prepared by adding water to the formulas to soak for 6 hours, then decocting at high temperature to prepare liquid medicine, standing at normal temperature until the temperature is reduced, and standing for 7 days to obtain the medicine for treating abdominal pain and diarrhea.
The preparation method comprises filtering the liquid medicine after standing for 7 days, and distilling and purifying to obtain the liquid medicine for treating abdominal pain and diarrhea.
The invention provides a medicament for treating abdominal pain and diarrhea of infants, children and even adults and a preparation method thereof, compared with the prior art, the medicament has the following advantages:
1. the medicine adopted by the invention is Chinese herbal medicine, and the cost of the prepared medicine is extremely low;
2. the preparation process of the medicine is simple and convenient;
3. the medicine of the present invention has the effective rate of 99% for treating abdominal pain and diarrhea of infants, children and adults, and has the characteristics of convenient use and quick effect.
DETAILED DESCRIPTION OF EMBODIMENT (S) OF INVENTION
Example 1, 55g of dried ginger and 45g of cinnamon are respectively soaked in water for 6 hours, the soaked cinnamon is boiled for 10 minutes, the soaked dried ginger is added, the mixture is decocted for 40 minutes, taken out and cooled to room temperature, and the mixture is placed for 7 days to obtain the medicine for treating diarrhea.
Example 2, after 55g of the dried ginger and 45g of the cinnamon are respectively placed in water for soaking for 6 hours, the soaked cinnamon is boiled and then boiled with slow fire for 10 minutes, the soaked dried ginger is added, the mixture is heated to be boiled and then decocted with slow fire for 40 minutes, then the mixture is taken out and cooled to room temperature, after filtration, the filtrate is distilled, and the medicine for treating diarrhea is obtained after distillation.
Example 3, after 55g of galangal and 45g of cinnamon are respectively placed in water to be soaked for 6 hours, the soaked cinnamon is boiled and then is boiled for 10 minutes by mild fire, then the soaked galangal is added into the cinnamon liquid medicine, the liquid medicine is prepared by further boiling for 40 minutes by mild fire after being heated to be boiled, the liquid medicine is placed at normal temperature to room temperature and then is placed for 7 days, and the medicine for treating diarrhea can be obtained after filtration.
Example 4, 55g of fructus piperis longi and 45g of cinnamon are respectively placed in water to be soaked for 6 hours, the soaked cinnamon is boiled and then boiled for 10 minutes by mild fire, the soaked fructus piperis longi is added into the cinnamon liquid medicine, the mixture is heated to boiling, then the mixture is continuously boiled for 40 minutes by mild fire to prepare the liquid medicine, the liquid medicine is placed at normal temperature to room temperature and then placed for 7 days, and the medicine for treating diarrhea can be obtained after filtration.
Example 5, after soaking 45g of fructus piperis longi, 10g of clove and 45g of cinnamon in water for 6 hours respectively, boiling the soaked cinnamon, decocting the boiled cortex piperis longi with slow fire for 10 minutes, adding the soaked fructus piperis longi and clove into the cinnamon liquid medicine, heating the mixture to boiling, continuing to decoct the mixture with slow fire for 40 minutes to prepare the liquid medicine, standing the mixture at normal temperature to room temperature, standing the mixture for 7 days, and filtering the mixture to obtain the medicine for treating diarrhea.
The prepared liquid medicine is used, (1) when in use, the liquid medicine is firstly applied to the navel part and then uniformly applied to the whole abdomen around the navel to moisten the whole abdomen, and the abdomen (dressing or comforter and the like) can be covered after the liquid medicine is completely absorbed; repeating the operation at intervals of 10-15 minutes; patients with mild abdominal pain and diarrhea can be cured within 1 to 2 hours generally; for patients with severe abdominal pain and diarrhea, the application method is repeated for 2 hours, and the purposes of relieving diarrhea and pain can be achieved within 3 to 4 hours. (2) The medicinal liquid can be used for treating abdominal pain or emesis independently according to the application method. (3) After patients suffering from cold deficiency of spleen and stomach are treated by the liquid medicine, the disease condition is relieved, the smearing times need to be increased properly, and the symptoms of abdominal pain and diarrhea can be cured within 12-24. (4) For patients who often suffer from abdominal pain and diarrhea, after the abdominal pain and the diarrhea are cured by adopting the liquid medicine for 3-4 times, the spleen, the stomach and the kidney functions of the patients can be effectively recovered and strengthened, and then the patients feel wind cold or eat uncooked and cold food materials, so that the symptoms of the abdominal pain and the diarrhea are basically avoided.
The applicant carried out statistics on 5876 cases treated for 30 years, wherein 2835 infants are treated with the age of 60 days at the minimum and 32 months at the maximum; there are 1768 children aged 3-12 years old and 1273 adults over 13 years old. Wherein the primary cure rate of the infant is 98 percent, the primary cure rate of the child is 95 percent, and the primary cure rate of the adult is 99 percent.
The liquid medicine of the invention is used for treating abdominal pain and diarrhea, and has the advantages of safety, no toxicity and quick response; especially for infant patients, has the characteristics of simple operation and convenient use.
Claims (8)
1. A medicine for treating abdominal pain and diarrhea is prepared from two or three of cortex Cinnamomi, Zingiberis rhizoma, rhizoma Alpiniae Officinarum, fructus Piperis Longi, fructus Litseae, and flos Caryophylli.
2. The medicament for treating abdominal pain and diarrhea as claimed in claim 1, wherein the first formula comprises 45g of cinnamon and 55g of dried ginger.
3. The medicine for treating abdominal pain and diarrhea as claimed in claim 1, wherein the formula two comprises 45g of cinnamon and 55g of galangal.
4. The medicine for treating abdominal pain and diarrhea as claimed in claim 1, wherein the third formula comprises 45g of cinnamon and 55g of fructus piperis longi.
5. The medicine for treating abdominal pain and diarrhea as claimed in claim 1, wherein the formula III is prepared from cortex Cinnamomi 45g, fructus Litseae Pungentis 45g, and flos Caryophylli 10 g.
6. The method comprises the steps of soaking cinnamon and other ingredients in water for 6 hours, heating the soaked cinnamon to boiling, decocting with slow fire for 10 minutes, adding the soaked rhizoma zingiberis, rhizoma galangae, fructus piperis longi, fructus piperis cubeba and clove into cinnamon liquid medicine according to the formula amount, heating to boiling, decocting with slow fire for 40 minutes, airing to normal temperature, filtering, and standing for 7 days to obtain the medicine for treating abdominal pain and diarrhea.
7. The formula as in claim 2, 3, 4 and 5, wherein the prepared medicines are soaked in water for 6 hours, decocted at high temperature for 40 minutes to prepare a liquid medicine, and then placed at room temperature for 7 days after the liquid medicine is placed at room temperature, so that the medicine for treating abdominal pain and diarrhea can be obtained.
8. The preparation method of claim 6, wherein the filtered medicinal liquid is distilled and purified for 7 days to obtain a medicinal liquid for treating abdominal pain and diarrhea.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911062030.4A CN111000964A (en) | 2019-11-01 | 2019-11-01 | Medicine for treating abdominal pain and diarrhea and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911062030.4A CN111000964A (en) | 2019-11-01 | 2019-11-01 | Medicine for treating abdominal pain and diarrhea and preparation method thereof |
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| Publication Number | Publication Date |
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| CN111000964A true CN111000964A (en) | 2020-04-14 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911062030.4A Pending CN111000964A (en) | 2019-11-01 | 2019-11-01 | Medicine for treating abdominal pain and diarrhea and preparation method thereof |
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| Country | Link |
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| CN (1) | CN111000964A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101912558A (en) * | 2010-08-09 | 2010-12-15 | 刘剑虹 | Medicine bag for protecting spleen and stomach |
| CN105998200A (en) * | 2016-06-17 | 2016-10-12 | 上海凯宝药业股份有限公司 | Application of traditional Chinese medicine composition in treating drug-induced abdominal pain caused by selective calcium antagonist |
-
2019
- 2019-11-01 CN CN201911062030.4A patent/CN111000964A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101912558A (en) * | 2010-08-09 | 2010-12-15 | 刘剑虹 | Medicine bag for protecting spleen and stomach |
| CN105998200A (en) * | 2016-06-17 | 2016-10-12 | 上海凯宝药业股份有限公司 | Application of traditional Chinese medicine composition in treating drug-induced abdominal pain caused by selective calcium antagonist |
Non-Patent Citations (3)
| Title |
|---|
| 傅永怀: "《妇儿科中成药精选》", 31 May 2014, 金盾出版社 * |
| 冯毅凡等: "双姜止痛软胶囊质量标准研究", 《中国新药杂志》 * |
| 国家药典委员会: "《中华人民共和国药典临床用药须知：2015年版.中药饮片卷》", 30 September 2017, 中国医药科技出版社 * |
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