CN110944630A - 精神药剂及其用途 - Google Patents
精神药剂及其用途 Download PDFInfo
- Publication number
- CN110944630A CN110944630A CN201880048781.8A CN201880048781A CN110944630A CN 110944630 A CN110944630 A CN 110944630A CN 201880048781 A CN201880048781 A CN 201880048781A CN 110944630 A CN110944630 A CN 110944630A
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- Prior art keywords
- amisulpride
- disorder
- compound
- condition
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000004089 psychotropic agent Substances 0.000 title description 2
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- 229960003036 amisulpride Drugs 0.000 claims abstract description 78
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 claims abstract description 68
- -1 5-HT2a Chemical compound 0.000 claims abstract description 55
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762508263P | 2017-05-18 | 2017-05-18 | |
| US62/508,263 | 2017-05-18 | ||
| PCT/US2018/033552 WO2018213813A2 (fr) | 2017-05-18 | 2018-05-18 | Agents psychotropes et leurs utilisations |
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| Publication Number | Publication Date |
|---|---|
| CN110944630A true CN110944630A (zh) | 2020-03-31 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201880048781.8A Pending CN110944630A (zh) | 2017-05-18 | 2018-05-18 | 精神药剂及其用途 |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP3625212A4 (fr) |
| CN (1) | CN110944630A (fr) |
| WO (1) | WO2018213813A2 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11377421B2 (en) | 2016-11-28 | 2022-07-05 | Lb Pharmaceuticals Inc. | Psychotropic agents and uses thereof |
| CN111233731B (zh) | 2016-11-28 | 2021-05-14 | Lb制药公司 | 精神药剂及其用途 |
| CN117074579B (zh) * | 2023-10-16 | 2023-12-22 | 江苏东科康德药业有限公司 | 一种氨磺必利口服溶液有关物质的分析方法 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6069165A (en) * | 1996-09-18 | 2000-05-30 | Synthelabo | Pharmaceutical compositions containing amisulpride and their therapeutic applications |
| US20050203130A1 (en) * | 2003-12-02 | 2005-09-15 | Erik Buntinx | Use of D4 and 5-HT2A antagonists, inverse agonists or partial agonists |
| US20100105755A1 (en) * | 2008-09-12 | 2010-04-29 | Auspex Pharmaceuticals, Inc. | Substituted benzamide modulators of dopamine receptor |
| CN110248655A (zh) * | 2016-11-28 | 2019-09-17 | Lb制药公司 | 精神药剂及其用途 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4210660A (en) * | 1978-12-20 | 1980-07-01 | Yamanouchi Pharmaceutical Co., Ltd. | Benzamide derivatives |
| WO2019113079A1 (fr) * | 2017-12-05 | 2019-06-13 | Sunovion Pharmaceuticals Inc. | Mélanges non racémiques et leurs utilisations |
-
2018
- 2018-05-18 CN CN201880048781.8A patent/CN110944630A/zh active Pending
- 2018-05-18 EP EP18801735.4A patent/EP3625212A4/fr active Pending
- 2018-05-18 WO PCT/US2018/033552 patent/WO2018213813A2/fr unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6069165A (en) * | 1996-09-18 | 2000-05-30 | Synthelabo | Pharmaceutical compositions containing amisulpride and their therapeutic applications |
| US20050203130A1 (en) * | 2003-12-02 | 2005-09-15 | Erik Buntinx | Use of D4 and 5-HT2A antagonists, inverse agonists or partial agonists |
| US20100105755A1 (en) * | 2008-09-12 | 2010-04-29 | Auspex Pharmaceuticals, Inc. | Substituted benzamide modulators of dopamine receptor |
| CN110248655A (zh) * | 2016-11-28 | 2019-09-17 | Lb制药公司 | 精神药剂及其用途 |
| CN111233731A (zh) * | 2016-11-28 | 2020-06-05 | Lb制药公司 | 精神药剂及其用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018213813A3 (fr) | 2019-12-12 |
| WO2018213813A2 (fr) | 2018-11-22 |
| EP3625212A4 (fr) | 2021-03-31 |
| EP3625212A2 (fr) | 2020-03-25 |
| WO2018213813A8 (fr) | 2019-11-07 |
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