CN110934955A - Compound composition for treating swollen sore throat and preparation method thereof - Google Patents
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- A61K2236/50—Methods involving additional extraction steps
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Abstract
The invention discloses a compound composition for treating swollen sore throat and a preparation method thereof, wherein the compound composition is prepared from the following components in parts by weight: 5-8 parts of bitter pomelo seeds, 0.8-1.5 parts of anoectochilus formosanus, 0.5-1 part of purslane, 1-2 parts of liquorice, 1-2 parts of luffa stem juice and 400 parts of water 200-ion. The method comprises the following steps: 1) cutting the luffa stem, and collecting luffa stem juice flowing out of the luffa stem; 2) soaking bitter pomelo seed, herba Anoectochili Roxburghii, herba Portulacae, and Glycyrrhrizae radix in water for 20-30min, boiling, keeping boiling for 3-5min, steaming with slow fire for 35-45min, and steaming with strong fire for 4-6 min; 3) adding the luffa stem juice collected in the step 1), boiling and keeping boiling for 3-5min, and then steaming with slow fire for 15-20min to obtain decoction, namely the compound composition for treating sore throat. The preparation method is simple and convenient, has wide medicine sources, utilizes the respective effects of the raw material components, and is matched with each other to effectively condition the swollen sore throat patients, and clinical application verifies that the health-care food therapy can achieve the purpose of health-care food therapy, has obvious effect and good safety, does not have toxic or side effect, and is suitable for swollen sore throat symptoms.
Description
Technical Field
The invention relates to the technical field of biological medicines, in particular to a compound composition for treating swollen sore throat and a preparation method thereof.
Background
Swollen and sore throat is one of the most common disease symptoms of people, and causes many reasons, such as cold, tonsillitis, improper diet, excessive use of throat and the like.
Swollen and sore throat is one of the most common disease symptoms of people, and the symptoms of acute swollen and sore throat, acute congestion, swelling and suppuration of tonsil, dysphagia and aversion to cold and high fever are shown in severe cases. The throat is the mouth of lung and stomach, and the pain of throat is caused by wind-fire and excessive phlegm obstructing the throat, deficiency-cold of lung and stomach or excessive heat of lung and stomach, and the disease condition is rapidly changed. The obstruction of qi and blood circulation can cause pain and the pain is not smooth. At present, a plurality of medicines for treating the swelling and pain in throat comprise western medicines and traditional Chinese medicines, the general treatment mainly comprises the western medicines, however, the western medicines treat the symptoms and the root causes, the antibacterial medicines are selected for treatment under the common condition, the swelling and pain in throat is caused to occur repeatedly, and the treatment effect is not ideal. Some traditional Chinese medicine treatments have slow response and time consumption, and the symptoms can not be quickly relieved, thereby influencing the use of patients. Therefore, the development of a safe and effective medicine is urgently needed to help patients get rid of pain and achieve the effect of rapidly treating both principal and secondary aspects of disease.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a compound composition for treating sore throat with good curative effect, high efficiency and no side effect and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
a compound composition for treating swollen sore throat is prepared from the following components in parts by weight:
5-8 parts of bitter shaddock seeds;
0.8-1.5 parts of anoectochilus formosanus;
0.5-1 part of purslane;
1-2 parts of liquorice;
1-2 parts of luffa stem juice;
200 portions of water and 400 portions of water.
Further, the compound composition for treating sore throat is prepared from the following components in parts by weight:
6 parts of bitter shaddock seeds;
1 part of anoectochilus formosanus;
0.75 part of purslane;
1.25 parts of liquorice;
1.5 parts of luffa stem juice;
300 parts of water.
The preparation method of the compound composition for treating the sore throat comprises the following steps:
1) cutting the luffa stem, and collecting luffa stem juice flowing out of the luffa stem;
2) soaking bitter pomelo seed, herba Anoectochili Roxburghii, herba Portulacae, and Glycyrrhrizae radix in water for 20-30min, boiling, keeping boiling for 3-5min, steaming with slow fire for 35-45min, and steaming with strong fire for 4-6 min;
3) adding the luffa stem juice collected in the step 1), boiling and keeping boiling for 3-5min, and then steaming with slow fire for 15-20min to obtain decoction, namely the compound composition for treating sore throat.
In the step 2), the temperature of water for soaking is 25-30 ℃.
Further, the preparation method also comprises the step 4), the decoction is concentrated into concentrated paste, and then the concentrated paste is sprayed, granulated and dried to obtain the compound composition granules for treating the sore throat.
Preferably, the concentration step is to concentrate the decoction at 45-50 deg.C to relative density of 1.05-1.30g/cm3The concentrated paste of (1).
Preferably, the concentrated paste is subjected to fluidized bed spray granulation drying by using a multifunctional granulator, and the steps are as follows:
preheating equipment: placing and jacking the material bed, sealing the equipment, and starting a fan and a heater to preheat the equipment;
feeding: stopping when the temperature of the material bed reaches 55 ℃, putting down the material bed, adding maltodextrin 50-60% of the weight of the extract into the material bed, jacking the material bed, and sealing the equipment;
preheating materials: setting the air inlet temperature to be 55-65 ℃, the material temperature to be 60-65 ℃ and the fan frequency to be 10-15Hz, and starting the fan and the heater to heat the maltodextrin;
spray granulation: when the temperature of the materials reaches 60 ℃, setting the rotating speed of a peristaltic pump to be 35-45rpm, setting the pressure of a spray gun to be 0.1-0.15Mpa, spraying the concentrated paste, starting spraying, and starting granulation;
drying and discharging: and after the spray granulation is finished, drying to obtain the compound composition granules for treating the sore throat.
By adopting the technical scheme, the compound composition for treating the sore throat is prepared by taking 5-8 parts of bitter shaddock seeds, 0.8-1.5 parts of anoectochilus formosanus, 0.5-1 part of purslane, 1-2 parts of liquorice and 1-2 parts of luffa stem juice as raw materials and steaming the raw materials. All the raw materials of the invention are cheap and easily available, and the preparation method is simple and easy to implement and has low cost.
Detailed Description
A compound composition for treating swollen sore throat is prepared from the following components in parts by weight:
5-8 parts of bitter shaddock seeds;
0.8-1.5 parts of anoectochilus formosanus;
0.5-1 part of purslane;
1-2 parts of liquorice;
1-2 parts of luffa stem juice;
200 portions of water and 400 portions of water.
The preparation method of the compound composition for treating the sore throat comprises the following steps:
1) cutting the luffa stem, and collecting luffa stem juice flowing out of the luffa stem;
2) soaking bitter pomelo seed, herba Anoectochili Roxburghii, herba Portulacae, and Glycyrrhrizae radix in water of 25-30 deg.C for 20-30min, boiling, keeping boiling for 3-5min, steaming with slow fire for 35-45min, and steaming with strong fire for 4-6 min;
3) adding the luffa stem juice collected in the step 1), boiling and keeping boiling for 3-5min, and then steaming with slow fire for 15-20min to obtain decoction, namely the compound composition for treating sore throat.
Further, the preparation method further comprises step 4) of concentrating the decoction at 45-50 deg.C to relative density of 1.05-1.30g/cm3Then adopting a multifunctional granulator to carry out fluidized bed spray granulation and drying, and comprising the following steps:
preheating equipment: placing and jacking the material bed, sealing the equipment, and starting a fan and a heater to preheat the equipment;
feeding: stopping when the temperature of the material bed reaches 55 ℃, putting down the material bed, adding maltodextrin 50-60% of the weight of the extract into the material bed, jacking the material bed, and sealing the equipment;
preheating materials: setting the air inlet temperature to be 55-65 ℃, the material temperature to be 60-65 ℃ and the fan frequency to be 10-15Hz, and starting the fan and the heater to heat the maltodextrin;
spray granulation: when the temperature of the materials reaches 60 ℃, setting the rotating speed of a peristaltic pump to be 35-45rpm, setting the pressure of a spray gun to be 0.1-0.15Mpa, spraying the concentrated paste, starting spraying, and starting granulation;
drying and discharging: and after the spray granulation is finished, drying to obtain the compound composition granules for treating the sore throat.
The present invention is further illustrated in detail with reference to the following specific examples:
example 1
A compound composition for treating swollen sore throat is prepared from the following components in parts by weight:
6g of bitter shaddock seeds;
1 g of anoectochilus formosanus;
0.75 g of purslane;
1.25 g of liquorice;
1.5 g of luffa stem juice;
300 g of water.
The preparation method comprises the following steps:
1) cutting the luffa stem, and collecting luffa stem juice flowing out of the luffa stem;
2) soaking bitter pomelo seed, herba Anoectochili Roxburghii, herba Portulacae, and Glycyrrhrizae radix in water of 25 deg.C for 30min, boiling, keeping boiling for 3min, steaming with slow fire for 45min, and steaming with strong fire for 4 min;
3) adding the luffa stem juice collected in the step 1), boiling and keeping boiling for 3min, and then steaming with slow fire for 20min to obtain a decoction, namely the compound composition for treating the sore throat.
Example 2
A compound composition for treating swollen sore throat is prepared from the following components in parts by weight:
5 parts of bitter shaddock seeds;
0.8 part of anoectochilus formosanus;
0.5 part of purslane;
1 part of liquorice;
2 parts of luffa stem juice;
and 250 parts of water.
The preparation method comprises the following steps:
1) cutting the luffa stem, and collecting luffa stem juice flowing out of the luffa stem;
2) soaking bitter pomelo seed, herba Anoectochili Roxburghii, herba Portulacae, and Glycyrrhrizae radix in water at 0 deg.C for 20min, boiling, keeping boiling for 5min, steaming with slow fire for 35min, and steaming with strong fire for 4 min;
3) adding the luffa stem juice collected in the step 1), boiling and keeping boiling for 5min, and then steaming with slow fire for 15min to obtain a decoction, namely the compound composition for treating the sore throat.
Example 3
A compound composition for treating swollen sore throat is prepared from the following components in parts by weight:
8 parts of bitter shaddock seeds;
1.5 parts of anoectochilus formosanus;
0.75 part of purslane;
1.5 parts of liquorice;
1.5 parts of luffa stem juice;
and 400 parts of water.
The preparation method comprises the following steps:
1) cutting the luffa stem, and collecting luffa stem juice flowing out of the luffa stem;
2) soaking bitter pomelo seed, herba Anoectochili Roxburghii, herba Portulacae, and Glycyrrhrizae radix in 28 deg.C water for 25min, boiling, keeping boiling for 4min, steaming with slow fire for 40min, and steaming with strong fire for 5 min;
3) adding the luffa stem juice collected in the step 1), boiling and keeping boiling for 4min, and then steaming for 18min with slow fire to obtain decoction, namely the compound composition for treating swollen sore throat.
Example 4
A compound composition for treating swollen sore throat is prepared from the following components in parts by weight:
8 parts of bitter shaddock seeds;
1.5 parts of anoectochilus formosanus;
1 part of purslane;
2 parts of liquorice;
2 parts of luffa stem juice;
and 400 parts of water.
The preparation method comprises the following steps:
1) cutting the luffa stem, and collecting luffa stem juice flowing out of the luffa stem;
2) soaking bitter pomelo seed, herba Anoectochili Roxburghii, herba Portulacae, and Glycyrrhrizae radix in 28 deg.C water for 25min, boiling, keeping boiling for 4min, steaming with slow fire for 40min, and steaming with strong fire for 5 min;
3) adding the luffa stem juice collected in the step 1), boiling and keeping boiling for 4min, and then steaming with slow fire for 18min to obtain a decoction;
4) concentrating the decoction at 45 deg.C to relative density of 1.05g/cm3Then adopting a multifunctional granulator to carry out fluidized bed spray granulation and drying, and comprising the following steps:
preheating equipment: placing and jacking the material bed, sealing the equipment, and starting a fan and a heater to preheat the equipment;
feeding: stopping when the temperature of the material bed reaches 55 ℃, putting down the material bed, adding maltodextrin 50-60% of the weight of the extract into the material bed, jacking the material bed, and sealing the equipment;
preheating materials: setting the air inlet temperature to be 55 ℃, the material temperature to be 60 ℃ and the fan frequency to be 10Hz, and starting the fan and the heater to heat the maltodextrin;
spray granulation: when the temperature of the materials reaches 60 ℃, setting the rotating speed of a peristaltic pump to be 35rpm, setting the pressure of a spray gun to be 0.1Mpa, spraying the concentrated paste, starting spraying, and starting granulation;
drying and discharging: and after the spray granulation is finished, drying to obtain the compound composition granules for treating the sore throat.
Example 5
A compound composition for treating swollen sore throat is prepared from the following components in parts by weight:
6 parts of bitter shaddock seeds;
1.0 part of anoectochilus formosanus;
0.8 part of purslane;
1.6 parts of liquorice;
1.25 parts of luffa stem juice;
300 parts of water.
The preparation method comprises the following steps:
1) cutting the luffa stem, and collecting luffa stem juice flowing out of the luffa stem;
2) soaking bitter pomelo seed, herba Anoectochili Roxburghii, herba Portulacae, and Glycyrrhrizae radix in 28 deg.C water for 25min, boiling, keeping boiling for 4min, steaming with slow fire for 40min, and steaming with strong fire for 5 min;
3) adding the luffa stem juice collected in the step 1), boiling and keeping boiling for 4min, and then steaming with slow fire for 18min to obtain a decoction;
4) concentrating the decoction at 50 deg.C to relative density of 1.30g/cm3Then adopting a multifunctional granulator to carry out fluidized bed spray granulation and drying, and comprising the following steps:
preheating equipment: placing and jacking the material bed, sealing the equipment, and starting a fan and a heater to preheat the equipment;
feeding: stopping when the temperature of the material bed reaches 55 ℃, putting down the material bed, adding maltodextrin 50-60% of the weight of the extract into the material bed, jacking the material bed, and sealing the equipment;
preheating materials: setting the air inlet temperature to be 65 ℃, the material temperature to be 65 ℃ and the fan frequency to be 15Hz, and starting the fan and the heater to heat the maltodextrin;
spray granulation: when the temperature of the materials reaches 60 ℃, setting the rotating speed of a peristaltic pump to be 45rpm, setting the pressure of a spray gun to be 0.15Mpa, spraying the concentrated paste, starting spraying, and starting granulation;
drying and discharging: and after the spray granulation is finished, drying to obtain the compound composition granules for treating the sore throat.
Application example
The compound composition of the invention is used for conditioning patients with sore throat, and has obvious curative effect, and typical cases are as follows:
1. in a certain forest, women and 26 years old, the main symptoms are dry cough, excessive phlegm and throat swelling and pain discomfort, and the patients are cured after taking the compound composition of the embodiment 1 twice a day and three days;
2. old male, 50 years old, the main symptom is swelling and pain of throat, the compound composition of the embodiment 1 of the invention is taken twice a day, three days are taken, and the disease is cured;
3. the major symptoms of the male, 31 years old, of Zhou Zhi are swelling and pain in throat and hoarse voice, and the patient can be cured by taking the compound composition of the embodiment 1 twice a day and three days.
Claims (7)
1. A compound composition for treating swollen sore throat is characterized in that: the composition is prepared from the following components in parts by weight:
5-8 parts of bitter shaddock seeds;
0.8-1.5 parts of anoectochilus formosanus;
0.5-1 part of purslane;
1-2 parts of liquorice;
1-2 parts of luffa stem juice;
200 portions of water and 400 portions of water.
2. The compound composition for treating sore throat according to claim 1, characterized in that: the composition is prepared from the following components in parts by weight:
6 parts of bitter shaddock seeds;
1 part of anoectochilus formosanus;
0.75 part of purslane;
1.25 parts of liquorice;
1.5 parts of luffa stem juice;
300 parts of water.
3. A method of preparing the compound composition for treating sore throat according to claim 1, wherein the method comprises the following steps: which comprises the following steps:
1) cutting the luffa stem, and collecting luffa stem juice flowing out of the luffa stem;
2) soaking bitter pomelo seed, herba Anoectochili Roxburghii, herba Portulacae, and Glycyrrhrizae radix in water for 20-30min, boiling, keeping boiling for 3-5min, steaming with slow fire for 35-45min, and steaming with strong fire for 4-6 min;
3) adding the luffa stem juice collected in the step 1), boiling and keeping boiling for 3-5min, and then steaming with slow fire for 15-20min to obtain decoction, namely the compound composition for treating sore throat.
4. The method for preparing a compound composition for treating sore throat according to claim 3, wherein: in the step 2), the temperature of water for soaking is 25-30 ℃.
5. The method for preparing a compound composition for treating sore throat according to claim 3, wherein: the preparation method also comprises a step 4) of concentrating the decoction into a concentrated paste, and then carrying out spray granulation and drying on the concentrated paste to obtain the compound composition granules for treating the sore throat.
6. The method for preparing the compound composition for treating swollen sore throat according to claim 5, which comprisesIs characterized in that: the concentration step is to concentrate the decoction at 45-50 deg.C to relative density of 1.05-1.30g/cm3The concentrated paste of (1).
7. The method for preparing a compound composition for treating sore throat according to claim 5, wherein: the concentrated paste is subjected to fluidized bed spray granulation drying by adopting a multifunctional granulator, and the steps are as follows:
preheating equipment: placing and jacking the material bed, sealing the equipment, and starting a fan and a heater to preheat the equipment;
feeding: stopping when the temperature of the material bed reaches 55 ℃, putting down the material bed, adding maltodextrin 50-60% of the weight of the extract into the material bed, jacking the material bed, and sealing the equipment;
preheating materials: setting the air inlet temperature to be 55-65 ℃, the material temperature to be 60-65 ℃ and the fan frequency to be 10-15Hz, and starting the fan and the heater to heat the maltodextrin;
spray granulation: when the temperature of the materials reaches 60 ℃, setting the rotating speed of a peristaltic pump to be 35-45rpm, setting the pressure of a spray gun to be 0.1-0.15Mpa, spraying the concentrated paste, starting spraying, and starting granulation;
drying and discharging: and after the spray granulation is finished, drying to obtain the compound composition granules for treating the sore throat.
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| CN201911419210.3A CN110934955A (en) | 2019-12-31 | 2019-12-31 | Compound composition for treating swollen sore throat and preparation method thereof |
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| CN106474376A (en) * | 2016-12-14 | 2017-03-08 | 陈俊玲 | A kind of Chinese medicine composition of pediatric treatment repetitive upper respiratory tract infection |
| CN109893641B (en) * | 2019-03-22 | 2021-09-17 | 重庆市中药研究院 | Direct-access oral ginger powder with functions of clearing and moistening throat and preparation method thereof |
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| CN104622946A (en) * | 2015-01-12 | 2015-05-20 | 福建农林大学 | Gynura bicolor heat-clearing buccal tablet and preparation method thereof |
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| Title |
|---|
| 钟红兰等: "中药柚核（种子）研究进展", 《亚太传统医药》 * |
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| Publication number | Publication date |
|---|---|
| CN114053368A (en) | 2022-02-18 |
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