CN109528954A - It is a kind of repair schneiderian membrane Chinese medicine composition and its application - Google Patents
It is a kind of repair schneiderian membrane Chinese medicine composition and its application Download PDFInfo
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- CN109528954A CN109528954A CN201910052650.3A CN201910052650A CN109528954A CN 109528954 A CN109528954 A CN 109528954A CN 201910052650 A CN201910052650 A CN 201910052650A CN 109528954 A CN109528954 A CN 109528954A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K36/238—Saposhnikovia
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
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Abstract
The invention discloses a kind of Chinese medicine composition for repairing schneiderian membrane and its applications, belong to technical field of traditional Chinese medicine.The Chinese medicine composition includes following components: honeysuckle, myrrh, the root bark of tree peony, dried orange peel, radix saposhnikoviae, the root of Dahurain angelica, fries Siberian cocklebur, the flower bud of lily magnolia, Poria cocos, dandelion, semen coicis, campanulaceae, Radix Astragali, Rhizoma Atractylodis Macrocephalae, catechu, borneol, Radix Glycyrrhizae at olibanum.The present invention also provides application of the above Chinese medicine composition in the drug that schneiderian membrane is repaired in preparation.Chinese medicine composition of the invention can repair rapidly impaired schneiderian membrane, efficient, long-acting, Small side effects, safe and convenient to use, and medicine source is extensive, and production is simple, can carry out clinical market popularization.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine, and in particular to it is a kind of repair schneiderian membrane Chinese medicine composition and its answer
With.
Background technique
Nasal cavity inner face has schneiderian membrane covering, is covered with blood vessel in schneiderian membrane, and nose can be made to play filtering to the air of sucking, adjust
Temperature and wet important function.When schneiderian membrane is stimulated, the capillary of schneiderian membrane will expand, congested, oedema, exudation.
Schneiderian membrane erosion is a kind of common frdquently encountered disease, mostly because wind-heat is invaded, causes to attack nose key in lung stomach accumulated heat, interior logical blood network, outer bright flesh
Caused by film.Schneiderian membrane ulcer refers to that nodosity infiltrates under schneiderian membrane, then rotten to the corn, can lead to cicatricial adhesion.Advanced stage is because of nose
Chamber drying forms a scab and atrophy occurs.Nasal decongestion is that acute rhinitis recurrent exerbation or treatment are not thorough and gradually evolve into nose and glue
Film is congested.Rhinitis is more common in schneiderian membrane swelling, is inflammatory stimulus schneiderian membrane and the enlargement that causes in nasal cavity.
Rhinitis, that is, nasal cavity inflammatory disease is virus, bacterium, allergen, various physical and chemical factors and certain systemic diseases
The inflammation of caused nasal membrane.It shows as that nasal decongestion, swelling, concha be plump, nasal cavity has clear nasal discharge or purulent secretion
Object, often there is nasal obstruction in patient, headache, dizziness, runny nose, nasal mucus refluence, limbs pain, malaise, smell degeneration, memory subtract
It moves back, the symptoms such as prolonged low grade fever.In acute rhinitis, if correct treatment, the inflammation of schneiderian membrane may spread to nose not in time
In sinus, mucous membrane in nasal sinus is made to generate acute inflammation, if acute rhinitis and acute sinusitis recurrent exerbation, is finally likely to form slow
Property rhinitis and chronic nasosinusitis；It is also possible to cause other complication, such as nasopharyngeal carcinoma, tympanitis, deafness disease.
Currently, the curative effect of medication for treating rhinitis on the market is undesirable, some courses for the treatment of are long, curative effect is low and easy recurrence, have
It treats that cumbersome, medicine irritation is strong, side effect is big, permanent damage is caused to schneiderian membrane, rhinitis is not had not only
Effect treatment is serious instead.If taking measures to repair impaired schneiderian membrane in root, enhance function of human body, so that it may shortest
Rhinitis Symptoms are eliminated in time, achieve the purpose that cure rhinitis.
Summary of the invention
For overcome the deficiencies in the prior art, impaired nose can be repaired rapidly the purpose of the present invention is to provide one kind to glue
The Chinese medicine composition of film, efficient, long-acting, Small side effects, safe and convenient to use, medicine source is extensive, cheap, and production is simple, can
Carry out clinical market popularization.
To solve the above problems, the technical solution adopted in the present invention is as follows:
A kind of Chinese medicine composition for repairing schneiderian membrane comprising following component by weight: 15~30 parts of honeysuckle,
5~10 parts of olibanum, 5~10 parts of myrrh, 10~15 parts of the root bark of tree peony, 10~15 parts of dried orange peel, radix saposhnikoviae 10~25 parts, 10~25 parts of the root of Dahurain angelica,
1~5 part of Siberian cocklebur of stir-fry, 10~15 parts of the flower bud of lily magnolia, 10~15 parts of Poria cocos, 10~20 parts of dandelion, 10~15 parts of semen coicis, campanulaceae 10~
15 parts, 10~25 parts of Radix Astragali, 10~25 parts of Rhizoma Atractylodis Macrocephalae, 1~5 part of catechu, 3~5 parts of borneol, 10~20 parts of Radix Glycyrrhizae.
As a preferred embodiment of the present invention, the Chinese medicine composition of the present invention for repairing schneiderian membrane includes pressing below
The component of parts by weight meter: 20~25 parts of honeysuckle, 6~8 parts of olibanum, 6~8 parts of myrrh, 12~15 parts of the root bark of tree peony, dried orange peel 12~15
Part, 15~20 parts of the root of Dahurain angelica, fries 2~4 parts of Siberian cocklebur, 12~15 parts of the flower bud of lily magnolia, 12~15 parts of Poria cocos, dandelion 12 at 15~20 parts of radix saposhnikoviae
~20 parts, 12~15 parts of semen coicis, 12~15 parts of campanulaceae, 12~25 parts of Radix Astragali, 12~25 parts of Rhizoma Atractylodis Macrocephalae, 2~4 parts of catechu, borneol 3
~5 parts, 12~18 parts of Radix Glycyrrhizae.
The present invention also provides a kind of pulvis for repairing schneiderian membrane comprising does made of Chinese medicine composition from the above mentioned
Powder.Specifically, the dry powder is the particle powder of 100 mesh or more.
The present invention also provides a kind of preparation methods of pulvis as described above for repairing schneiderian membrane, specifically include following
Step: weighing each component by formula ratio, cleans, removes heavy metal, drying, is milled to the particle powder of 100 mesh or more, sterilizing to get
The pulvis for repairing schneiderian membrane.
The present invention also provides a kind of drops for repairing schneiderian membrane comprising Chinese medicine composition and figuration from the above mentioned
Agent.Specifically, the excipient is sesame oil.
The present invention also provides a kind of preparation methods of drops as described above for repairing schneiderian membrane comprising following step
It is rapid:
(1) olibanum and myrrh are weighed by formula ratio, fresh black sesame oil is added, covered and impregnate 1~2 day, filtering takes medicine oil
It is spare；
(2) honeysuckle is weighed by formula ratio, the root bark of tree peony, dried orange peel, radix saposhnikoviae, the root of Dahurain angelica, fry Siberian cocklebur, the flower bud of lily magnolia, Poria cocos, dandelion, the heart of a lotus seed
The seed of jog's tears, campanulaceae, Radix Astragali, Rhizoma Atractylodis Macrocephalae, catechu, Radix Glycyrrhizae are respectively washed the above raw material, remove heavy metal, drying, mixing each component until
Uniformly, fresh black sesame oil is added, covers and impregnates 30~60min；
(3) mixture obtained by medicine oil obtained by step (1) and step (2) is mixed, is heated to boiling with mild fire,
It is separated by filtration medicine oil and the dregs of a decoction while hot, when medicine oil is cooled to 60~70 DEG C, pours into sterile chamber rapidly；
(4) borneol is weighed by formula ratio, is ground into fine powder, borneol fine powder is poured into medicine oil obtained by step (3), is added
Lid sealing is dispensed after being cooled to room temperature with sterile chamber to get the drops of the reparation schneiderian membrane.
As a preferred embodiment of the present invention, 5~10min is kept after medicine oil being heated to boiling in the step (3).
The present invention also provides a kind of application of Chinese medicine composition as described above in the drug that schneiderian membrane is repaired in preparation.
Side's solution of the invention is as follows:
Prescription of the invention is using honeysuckle as monarch drug in a prescription, honeysuckle dispelling wind-heat, removing summer-heat blood poison, qi-restoratives treatment wind, antibacterial anti-inflammatory,
The absorption that local blood circulation can be improved, schneiderian membrane is protected and promote mucous secretion object.
Olibanum in prescription of the invention, blood-activating and qi-promoting analgesic, detumescence and promoting granulation；Myrrh dissipates blood stasis eliminatings, detumescence ding-tong；It is red
Skin, clearing heat and cooling blood, activating microcirculation and removing stasis medicinal；Dried orange peel, qi-regulating eliminating dampness.The above component is ministerial drug altogether, and blood-activating and qi-promoting, swelling and pain relieving, stasis eliminatings are raw
Flesh can eliminate the symptoms such as nasal decongestion, redness, plumpness.
The root of Dahurain angelica in this prescription, wind-damp dispelling, apocenosis of invigorating blood circulation, myogenic pain relieving；Radix saposhnikoviae delivers wind-dispelling, expel endogenous wind to relieve convulsion；Pu Gong
English, clearing heat and detoxicating, dispersing swelling and dissipating binds, dampness removing are treating stranguria.Semen coicis, clearing away heat and eliminating pus, eliminating dampness and heat；Campanulaceae, open the inhibited lung-energy, eliminating the phlegm row
Purulence.Siberian cocklebur is fried, mild dredge reaches, and acrid flavour relieve heat, bitter eliminating dampness is turbid, is apt to clearing the nasal passage to remove nasal obstruction, only forehead and intranasal distending pain, for controlling
Treat nasosinusitis headache, loss of smell, when flow turbid tears.The flower bud of lily magnolia, dispersing wind and cold, clearing the nasal passage, antipyretic-antalgic, QI invigorating apocenosis improve local blood
The absorption that liquid recycles, protects schneiderian membrane and promote mucous secretion object, movement, improvement Dou Kou drainage conducive to cilium in sinus.Ice
Piece, sensible analgesic, anti-corrosion are anti-inflammatory.Radix Astragali, promoting pus discharge and tissue regeneration, invigorating qi for consolidating superficies, enhancing body's immunity.Rhizoma Atractylodis Macrocephalae, it is strengthening the spleen and replenishing qi, dry
Wet Li Shui.Poria cocos, clearing damp and promoting diuresis, invigorating the spleen calming heart.Catechu, heat on clear diaphragm are acted as expectorant, promoting granulation and relieving pain, and eye is controlled in hemostasis, hygroscopic
Conjunctiva, the inflammation such as nasal cavity.The above component is adjutant.
Wherein, the root of Dahurain angelica, radix saposhnikoviae match, and lead to stagnant and dissipate its knot, from outer relieving heat toxin；Dandelion, semen coicis, campanulaceae match,
The clearing heat and detoxicating, carbuncle that disappears apocenosis；The sensible analgesic of Siberian cocklebur, the flower bud of lily magnolia, QI invigorating apocenosis are fried, borneol is equipped with, reinforces the power of penetrating uplink, disease and evil
Go out with purulence, to release compressing, damage of the stimulants such as nasal mucus to schneiderian membrane；Catechu, hygroscopic myogenic sore can repair nose
Mucosal ulcer is not held back；Radix Astragali, Rhizoma Atractylodis Macrocephalae QI invigorating rise clearly, and Poria cocos removes water-wet, can eliminate schneiderian membrane oedema.
Prescription of the invention is to make medicine with Radix Glycyrrhizae, and Radix Glycyrrhizae is invigorated the spleen and benefited qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, is adjusted
With all medicines.
Our all medicines share, play altogether clearing heat and detoxicating, apocenosis anti-corrosion, sensible analgesic, activating microcirculation and removing stasis medicinal, reinvigoration function.
Compared with prior art, the beneficial effects of the present invention are:
Etiology and pathogenesis of the present invention according to impaired schneiderian membrane, the reasonable Chinese medicine composition of modulating ligand 5, the Chinese medicine composition
Clearing heat and detoxicating, apocenosis anti-corrosion, sensible analgesic, activating microcirculation and removing stasis medicinal, it is rapid-action and significant in efficacy, so as to repair impaired nose rapidly
Mucous membrane.In addition, the pulvis and drops provided by the invention containing above-mentioned Chinese medicine composition, efficient, long-acting, safe and convenient to use,
By nasal cavity applied medicine, so that drug effect is gone directly lesion, remove the virus and bacteria of nasal cavity, cut off the growth source of virus and bacteria, purify nasal cavity
Environment improves nasal cavity microcirculation；Promote the secretion of lysozyme in schneiderian membrane, improves nasal mucosal immune sterilization, antibacterial anti-inflammatory, anti-mistake
Quick ability promotes new healthy cell and organizational growth, to restore schneiderian membrane function, is really achieved the mesh of rhinitis treating both manifestation and root cause of disease
's.It is an advantage of the invention that do not take medicine, do not have an injection, only needing external application, easy to use, therapeutic process no pain, significant effect, no
It is easy to recur；It has no toxic side effect, have no adverse reaction, is healthy and safe, especially suitable child patient uses.
Specific embodiment
Invention is further described in detail for specific embodiment below.
Embodiment 1:
A kind of Chinese medicine composition for repairing schneiderian membrane comprising following components: honeysuckle 30g, olibanum 8g, myrrh 8g, pellet
Skin 15g, dried orange peel 15g, radix saposhnikoviae 20g, root of Dahurain angelica 20g, Siberian cocklebur 3g, flower bud of lily magnolia 15g, Poria cocos 15g, dandelion 15g, semen coicis 12g, tangerine are fried
Obstruct 12g, Radix Astragali 12g, Rhizoma Atractylodis Macrocephalae 12g, catechu 3g, borneol 3g, Radix Glycyrrhizae 15g.
A kind of pulvis for repairing schneiderian membrane comprising the dry powder of 200 mesh made of Chinese medicine composition from the above mentioned, system
Preparation Method is cleaned, removes heavy metal, drying, it is micro- to be milled to 200 purposes specifically includes the following steps: weigh each component by formula ratio
Grain powder sterilizes to get the pulvis for repairing schneiderian membrane.
Embodiment 2:
A kind of Chinese medicine composition for repairing schneiderian membrane comprising following components: honeysuckle 25g, olibanum 5g, myrrh 5g, pellet
Skin 10g, dried orange peel 10g, radix saposhnikoviae 15g, root of Dahurain angelica 15g, Siberian cocklebur 1g, flower bud of lily magnolia 10g, Poria cocos 10g, dandelion 10g, semen coicis 10g, tangerine are fried
Obstruct 10g, Radix Astragali 10g, Rhizoma Atractylodis Macrocephalae 10g, catechu 1g, borneol 5g, Radix Glycyrrhizae 10g.
A kind of pulvis for repairing schneiderian membrane comprising the dry powder of 100 mesh made of Chinese medicine composition from the above mentioned, system
Preparation Method is cleaned, removes heavy metal, drying, it is micro- to be milled to 100 purposes specifically includes the following steps: weigh each component by formula ratio
Grain powder sterilizes to get the pulvis for repairing schneiderian membrane.
Embodiment 3:
It is a kind of repair schneiderian membrane Chinese medicine composition comprising following components: honeysuckle 15g, olibanum 10g, myrrh 10g,
Root bark of tree peony 12g, dried orange peel 12g, radix saposhnikoviae 10g, root of Dahurain angelica 10g, fry Siberian cocklebur 5g, flower bud of lily magnolia 12g, Poria cocos 12g, dandelion 12g, semen coicis 15g,
Campanulaceae 15g, Radix Astragali 15g, Rhizoma Atractylodis Macrocephalae 15g, catechu 5g, borneol 4g, Radix Glycyrrhizae 10g.
A kind of pulvis for repairing schneiderian membrane comprising the dry powder of 300 mesh made of Chinese medicine composition from the above mentioned, system
Preparation Method is cleaned, removes heavy metal, drying, it is micro- to be milled to 300 purposes specifically includes the following steps: weigh each component by formula ratio
Grain powder sterilizes to get the pulvis for repairing schneiderian membrane.
Embodiment 4:
A kind of Chinese medicine composition for repairing schneiderian membrane comprising following components: honeysuckle 30g, olibanum 8g, myrrh 8g, pellet
Skin 15g, dried orange peel 15g, radix saposhnikoviae 20g, root of Dahurain angelica 20g, Siberian cocklebur 3g, flower bud of lily magnolia 15g, Poria cocos 15g, dandelion 15g, semen coicis 12g, tangerine are fried
Obstruct 12g, Radix Astragali 12g, Rhizoma Atractylodis Macrocephalae 12g, catechu 3g, borneol 3g, Radix Glycyrrhizae 15g.
A kind of drops for repairing schneiderian membrane comprising Chinese medicine composition and excipient sesame oil from the above mentioned, preparation
Method specifically includes the following steps:
(1) olibanum and myrrh are weighed by formula ratio, fresh black sesame oil is added, covered and impregnate 1 day, filtering takes medicine oil standby
With；
(2) honeysuckle is weighed by formula ratio, the root bark of tree peony, dried orange peel, radix saposhnikoviae, the root of Dahurain angelica, fry Siberian cocklebur, the flower bud of lily magnolia, Poria cocos, dandelion, the heart of a lotus seed
The seed of jog's tears, campanulaceae, Radix Astragali, Rhizoma Atractylodis Macrocephalae, catechu, Radix Glycyrrhizae are respectively washed the above raw material, remove heavy metal, drying, mixing each component until
Uniformly, fresh black sesame oil is added, covers and impregnates 60min；
(3) mixture obtained by medicine oil obtained by step (1) and step (2) is mixed, is heated to boiling with mild fire
And boiling 5min is kept, it is separated by filtration medicine oil and the dregs of a decoction while hot, when medicine oil is cooled to 60 DEG C, pours into sterile chamber rapidly；
(4) borneol is weighed by formula ratio, is ground into fine powder, borneol fine powder is poured into medicine oil obtained by step (3), is added
Lid sealing is dispensed after being cooled to room temperature with sterile chamber to get the drops of the reparation schneiderian membrane.
Embodiment 5:
A kind of Chinese medicine composition for repairing schneiderian membrane comprising following components: honeysuckle 25g, olibanum 5g, myrrh 5g, pellet
Skin 10g, dried orange peel 10g, radix saposhnikoviae 15g, root of Dahurain angelica 15g, Siberian cocklebur 1g, flower bud of lily magnolia 10g, Poria cocos 10g, dandelion 10g, semen coicis 10g, tangerine are fried
Obstruct 10g, Radix Astragali 10g, Rhizoma Atractylodis Macrocephalae 10g, catechu 1g, borneol 5g, Radix Glycyrrhizae 10g.
A kind of drops for repairing schneiderian membrane comprising Chinese medicine composition and excipient sesame oil from the above mentioned, preparation
Method specifically includes the following steps:
(1) olibanum and myrrh are weighed by formula ratio, fresh black sesame oil is added, covered and impregnate 2 days, filtering takes medicine oil standby
With；
(2) honeysuckle is weighed by formula ratio, the root bark of tree peony, dried orange peel, radix saposhnikoviae, the root of Dahurain angelica, fry Siberian cocklebur, the flower bud of lily magnolia, Poria cocos, dandelion, the heart of a lotus seed
The seed of jog's tears, campanulaceae, Radix Astragali, Rhizoma Atractylodis Macrocephalae, catechu, Radix Glycyrrhizae are respectively washed the above raw material, remove heavy metal, drying, mixing each component until
Uniformly, fresh black sesame oil is added, covers and impregnates 45min；
(3) mixture obtained by medicine oil obtained by step (1) and step (2) is mixed, is heated to boiling with mild fire
And boiling 10min is kept, it is separated by filtration medicine oil and the dregs of a decoction while hot, when medicine oil is cooled to 65 DEG C, pours into sterile chamber rapidly；
(4) borneol is weighed by formula ratio, is ground into fine powder, borneol fine powder is poured into medicine oil obtained by step (3), is added
Lid sealing is dispensed after being cooled to room temperature with sterile chamber to get the drops of the reparation schneiderian membrane.
Embodiment 6:
It is a kind of repair schneiderian membrane Chinese medicine composition comprising following components: honeysuckle 15g, olibanum 10g, myrrh 10g,
Root bark of tree peony 12g, dried orange peel 12g, radix saposhnikoviae 10g, root of Dahurain angelica 10g, fry Siberian cocklebur 5g, flower bud of lily magnolia 12g, Poria cocos 12g, dandelion 12g, semen coicis 15g,
Campanulaceae 15g, Radix Astragali 15g, Rhizoma Atractylodis Macrocephalae 15g, catechu 5g, borneol 4g, Radix Glycyrrhizae 10g.
A kind of drops for repairing schneiderian membrane comprising Chinese medicine composition and excipient sesame oil from the above mentioned, preparation
Method specifically includes the following steps:
(1) olibanum and myrrh are weighed by formula ratio, fresh black sesame oil is added, covered and impregnate 1.5 days, filtering takes medicine oil
It is spare；
(2) honeysuckle is weighed by formula ratio, the root bark of tree peony, dried orange peel, radix saposhnikoviae, the root of Dahurain angelica, fry Siberian cocklebur, the flower bud of lily magnolia, Poria cocos, dandelion, the heart of a lotus seed
The seed of jog's tears, campanulaceae, Radix Astragali, Rhizoma Atractylodis Macrocephalae, catechu, Radix Glycyrrhizae are respectively washed the above raw material, remove heavy metal, drying, mixing each component until
Uniformly, fresh black sesame oil is added, covers and impregnates 60min；
(3) mixture obtained by medicine oil obtained by step (1) and step (2) is mixed, is heated to boiling with mild fire
And boiling 8min is kept, it is separated by filtration medicine oil and the dregs of a decoction while hot, when medicine oil is cooled to 70 DEG C, pours into sterile chamber rapidly；
(4) borneol is weighed by formula ratio, is ground into fine powder, borneol fine powder is poured into medicine oil obtained by step (3), is added
Lid sealing is dispensed after being cooled to room temperature with sterile chamber to get the drops of the reparation schneiderian membrane.
Using pulvis, the drops of reparation schneiderian membrane of the invention, treatment schneiderian membrane is impaired year altogether from 2017 to 2018
Patients with rhinitis 203, wherein male patient 108, female patient 95, the age is 5 years old the smallest, and maximum 60 years old, and to 203
Example patient carries out follow-up investigation, cures 183, and cure rate is up to 90.1%.It takes effect within patient with slight symptoms's continuous use 2~3 days, a Zhou Zhi
More, it cures within patient with severe symptoms's medication 30~50 days.By 6 to 12 months follow-up observation, patient was without any adverse reactions, non-stimulated
Symptom occurs, it was demonstrated that it is significant in efficacy that schneiderian membrane of the invention repairs pulvis, drops, securely and reliably.
Typical case:
Case one: Zhao XX, male, 50 years old, allergic rhinitis twenties years, rhiocnesmus, runny nose, sneeze were frequent, schneiderian membrane is rotten to the corn.
On January 9th, 2017 is treated with pulvis of the invention, without sneeze phenomenon after 5 days, then with of the invention drops treatment 30 days, is cured.
Follow-up 1 year without recurrence.
Case two: king XX, male 9 years old, nasosinusitis 5 years, check the hyperemia of discovery bilateral concha, enlargement, headache, nasal obstruction, nose
Itch, sleep open one's mouth breathing, sometimes nose is bleeding, have a large amount of purulent secretions, prolonged low grade fever, nasal decongestion swelling.In March, 2017
Nose was sprayed with pulvis of the invention in 26th, second day, nasal obstruction symptom disappeared, and checks after medication 30 days to local hospital, and symptom is basic
It disappears, is discontinued after a week and is treated 20 days with drops of the invention again, nasosinusitis various symptoms disappear, recovery from illness.1 year nothing of follow-up
Recurrence.
Case three: Lee X, female, 45 years old, the rhinitis chronic more than ten years, nasal obstruction, headache, nasal mucus refluence, schneiderian membrane were red and swollen.2017
On May 16, is treated with pulvis of the invention, and without nasal obstruction phenomenon after 2 days, then with drops treatment of the invention, rhinitis is each after 15 days
Kind symptom disappears, and cures.Follow-up half a year is without recurrence.
Case four: Lyu XX, male, 5 years old, rhinitis chronic 1 year, nasal obstruction, runny nose, schneiderian membrane swelling.On May 19th, 2017 use
Pulvis treatment of the invention, is cured after a week.Follow-up 1 year without recurrence.
Case five: yellow X, female, 8 years old, allergic rhinitis 3 years, rhiocnesmus, eye were itched, schneiderian membrane is pale, and annual 8 to September allergy send out
Itch exacerbation of symptoms.On June 20th, 2017 is treated with drops of the invention, and symptom of itching after 15 days disappears, and 2017 8 to September, nose
Itch, eye itch symptom disappearance, cure.Follow-up 1 year without recurrence.
Case six: Hu XX, female, 60 years old, nasosinusitis twenties years, nasal obstruction, nasal mucus were flow backwards, nasal decongestion swelling.2018
On March 25, in is treated 5 days with pulvis of the invention, and nasal obstruction symptom disappears, then is treated 20 days with drops of the invention, and nasosinusitis is each
Kind symptom disappears, recovery from illness.Follow-up half a year is without recurrence.
In conclusion Chinese medicine composition and its preparation of the invention, can repair rapidly impaired schneiderian membrane, it is efficient, long
Effect, Small side effects, safe and convenient to use, medicine source is extensive, and production is simple, can carry out clinical market popularization.
The above embodiment is only the preferred embodiment of the present invention, and the scope of protection of the present invention is not limited thereto,
The variation and replacement for any unsubstantiality that those skilled in the art is done on the basis of the present invention belong to institute of the present invention
Claimed range.
Claims (10)
1. a kind of Chinese medicine composition for repairing schneiderian membrane, it is characterised in that: including following component by weight: honeysuckle 15
~30 parts, 5~10 parts of olibanum, 5~10 parts of myrrh, 10~15 parts of the root bark of tree peony, 10~15 parts of dried orange peel, windproof 10~25 parts, the root of Dahurain angelica 10
~25 parts, fry 1~5 part of Siberian cocklebur, 10~15 parts of the flower bud of lily magnolia, 10~15 parts of Poria cocos, 10~20 parts of dandelion, 10~15 parts of semen coicis,
10~15 parts of campanulaceae, 10~25 parts of Radix Astragali, 10~25 parts of Rhizoma Atractylodis Macrocephalae, 1~5 part of catechu, 3~5 parts of borneol, 10~20 parts of Radix Glycyrrhizae.
2. it is according to claim 1 repair schneiderian membrane Chinese medicine composition, it is characterised in that: including it is following by weight
Component: 20~25 parts of honeysuckle, 6~8 parts of olibanum, 6~8 parts of myrrh, 12~15 parts of the root bark of tree peony, 12~15 parts of dried orange peel, radix saposhnikoviae 15
~20 parts, 15~20 parts of the root of Dahurain angelica, stir-fry 2~4 parts of Siberian cocklebur, 12~15 parts of the flower bud of lily magnolia, 12~15 parts of Poria cocos, 12~20 parts of dandelion, the heart of a lotus seed
It is 12~15 parts of the seed of jog's tears, 12~15 parts of campanulaceae, 12~25 parts of Radix Astragali, 12~25 parts of Rhizoma Atractylodis Macrocephalae, 2~4 parts of catechu, 3~5 parts of borneol, sweet
12~18 parts of grass.
3. a kind of pulvis for repairing schneiderian membrane, it is characterised in that: including being made of Chinese medicine composition of any of claims 1 or 2
Dry powder.
4. the pulvis according to claim 3 for repairing schneiderian membrane, it is characterised in that: the dry powder is the micro- of 100 mesh or more
Grain powder.
5. a kind of preparation method of the pulvis of the reparation schneiderian membrane as described in right 3 or 4, it is characterised in that: the following steps are included:
Each component is weighed by formula ratio, cleans, remove heavy metal, drying, is milled to the particle powder of 100 mesh or more, sterilizing is repaired to get described
The pulvis of multiple schneiderian membrane.
6. a kind of drops for repairing schneiderian membrane, it is characterised in that: including by Chinese medicine composition described in claim 1 and figuration
Agent.
7. the drops according to claim 6 for repairing schneiderian membrane, it is characterised in that: the excipient is sesame oil.
8. a kind of preparation method of the drops as claimed in claim 6 for repairing schneiderian membrane, it is characterised in that: including following step
It is rapid:
(1) olibanum and myrrh are weighed by formula ratio, fresh black sesame oil is added, covered and impregnate 1~2 day, filtering takes medicine oil standby
With；
(2) by formula ratio weigh honeysuckle, the root bark of tree peony, dried orange peel, radix saposhnikoviae, the root of Dahurain angelica, fry Siberian cocklebur, the flower bud of lily magnolia, Poria cocos, dandelion, semen coicis,
Campanulaceae, Radix Astragali, Rhizoma Atractylodis Macrocephalae, catechu, Radix Glycyrrhizae are respectively washed the above raw material, remove heavy metal, drying, mixing each component until uniformly,
Fresh black sesame oil is added, covers and impregnates 30~60min；
(3) mixture obtained by medicine oil obtained by step (1) and step (2) is mixed, is heated to boiling with mild fire, while hot
It is separated by filtration medicine oil and the dregs of a decoction, when medicine oil is cooled to 60~70 DEG C, is poured into sterile chamber rapidly；
(4) borneol is weighed by formula ratio, is ground into fine powder, borneol fine powder is poured into medicine oil obtained by step (3), covered close
Envelope is dispensed after being cooled to room temperature with sterile chamber to get the drops of the reparation schneiderian membrane.
9. the preparation method of the drops according to claim 8 for repairing schneiderian membrane, it is characterised in that: in the step (3)
5~10min is kept after medicine oil is heated to boiling.
10. a kind of application of Chinese medicine composition as claimed in claim 1 or 2 in the drug that schneiderian membrane is repaired in preparation.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1132645A (en) * | 1995-12-01 | 1996-10-09 | 朱宝昌 | Nasosinusitis granule |
| CN1824195A (en) * | 2005-12-30 | 2006-08-30 | 曹玉梅 | Medicien for treating nasitis and nasosinusitis |
| CN104000893A (en) * | 2014-06-21 | 2014-08-27 | 徐显廷 | Traditional Chinese medicine oral liquid for treating rhinitis |
-
2019
- 2019-01-21 CN CN201910052650.3A patent/CN109528954A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1132645A (en) * | 1995-12-01 | 1996-10-09 | 朱宝昌 | Nasosinusitis granule |
| CN1824195A (en) * | 2005-12-30 | 2006-08-30 | 曹玉梅 | Medicien for treating nasitis and nasosinusitis |
| CN104000893A (en) * | 2014-06-21 | 2014-08-27 | 徐显廷 | Traditional Chinese medicine oral liquid for treating rhinitis |
Non-Patent Citations (1)
| Title |
|---|
| 张玉兰 等: "中药鼻炎膏治疗慢性鼻炎的临床研究", 《中国中西医结合耳鼻咽喉科杂志》 * |
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Application publication date: 20190329 |