CN110934900A - External ointment for treating burns and scalds - Google Patents

External ointment for treating burns and scalds Download PDF

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Publication number
CN110934900A
CN110934900A CN202010058418.3A CN202010058418A CN110934900A CN 110934900 A CN110934900 A CN 110934900A CN 202010058418 A CN202010058418 A CN 202010058418A CN 110934900 A CN110934900 A CN 110934900A
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sesame oil
decoction pieces
scalds
lithospermum
borneol
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郜会粉
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
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  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Insects & Arthropods (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
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Abstract

The invention relates to an external ointment for treating burns and scalds, which comprises 300-1000 g of Chinese angelica, 100-300 g of lithospermum, 500-1500 g of sesame oil, 20-80 g of beeswax and 20-50 g of borneol, wherein the components of the external ointment for treating burns and scalds are 500 g of Chinese angelica, 200 g of lithospermum, 1000 g of sesame oil, 50 g of beeswax and 30 g of borneol; heating sesame oil to about 40-60 ℃, adding angelica sinensis decoction pieces, frying with soft fire until the sesame oil turns yellow, adding lithospermum decoction pieces, frying with soft fire for 10-30 minutes, completely leaching out the herbal medicines, adding beeswax, slowly stirring while turning off the fire, cooling to 30-50 ℃, adding smashed borneol, uniformly stirring, placing in a cool place, heating sesame oil to about 50 ℃, adding angelica sinensis decoction pieces, frying with soft fire until the sesame oil turns yellow, adding lithospermum decoction pieces, frying with soft fire for 20 minutes, completely leaching out the herbal medicines, adding beeswax, slowly stirring while turning off the fire, cooling to 40 ℃, adding smashed borneol, uniformly stirring, and placing in a cool place for standby; the invention has the advantages of clearing heat and relieving pain, and having the efficacy of removing necrotic tissue and promoting tissue regeneration.

Description

External ointment for treating burns and scalds
Technical Field
The invention belongs to the technical field of burn, and particularly relates to an external ointment for treating burn and scald.
Background
Burns generally refer to tissue damage caused by heat (including hot liquids, vapors, hot gases, flames, electrical energy, chemicals, radiation, glowing metallic liquids or solids, etc.). Mainly refers to the damage of skin or mucous membrane, and serious one can also injure other tissues, and thermal injury caused by hot liquid and steam is called scald, and thermal injury caused by flame and electric current is called burn. The main clinical symptoms after skin burn are: redness, swelling, pain, burning sensation, localized redness and swelling, weeping, blisters, and severe pain of the skin. Clinically, the burn is divided into third-degree burn and first-degree burn, and clinically, the burn is characterized by skin burn, erythema and local skin red, swelling and hot pain; second degree burn: superficial second degree is dermal superficial burn, local blister, thin blister wall, extreme edema with severe pain, erosion and scab formed by blister; third degree burn: the depth of burn reaches the whole layer or deeper of skin, and the skin is pale or forms eschar without pain. If the burn is not treated in time, infection can be further caused, patients with deep second-degree and third-degree injuries often have severe pain, nausea, vomiting, anuresis and shock sometimes occur, patients with wound infection can have high fever, chill and even septicemia, symptoms after burn are more, for example, more exudate exists after burn, tissue necrosis is particularly rapid within 72 hours after burn, debridement is a big problem, all necrotic tissues are cut off by thorough debridement, a part of existing living tissues can be sacrificed, a plurality of important tissue structures are lost, if debridement is not thorough, the wound of the inactivated tissues is left, and in addition, the wound of the early wound is excessively oozed, and secondary infection is easily caused; there is a need to develop an external ointment for treating burns and scalds, which has the effects of clearing heat, relieving pain, and promoting tissue regeneration; therefore, the development of the external ointment for treating the burns and scalds, which has the effects of clearing heat, relieving pain and promoting tissue regeneration, has very important significance.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides an external ointment for treating burns and scalds, which has the effects of clearing heat, relieving pain, and promoting tissue regeneration.
The purpose of the invention is realized as follows: the externally applied ointment for treating burns and scalds comprises 300-1000 g of angelica sinensis, 100-300 g of lithospermum, 500-1500 g of sesame oil, 20-80 g of beeswax and 20-50 g of borneol.
The external ointment for treating burns and scalds comprises 500 g of angelica, 200 g of lithospermum, 1000 g of sesame oil, 50 g of beeswax and 30 g of borneol.
The external ointment for treating burns and scalds comprises 300 g of angelica, 100 g of lithospermum, 500 g of sesame oil, 20 g of beeswax and 20 g of borneol.
The external ointment for treating burns and scalds comprises 1000 g of angelica, 300 g of lithospermum, 1500 g of sesame oil, 80 g of beeswax and 50 g of borneol.
The external ointment for treating burns and scalds comprises 400 g of angelica, 150 g of lithospermum, 800 g of sesame oil, 60 g of beeswax and 40 g of borneol.
The sesame oil is heated to about 40-60 degrees, the angelica sinensis decoction pieces are placed into the sesame oil, the sesame oil is fried to be yellow with soft fire, the lithospermum decoction pieces are placed into the sesame oil, the sesame oil is fried for 10-30 minutes with soft fire, all the herbal medicines are drained out, the beeswax is placed into the sesame oil, the mixture is slowly stirred without stopping the fire, the mixture is cooled to 30-50 degrees, the smashed borneol is added into the mixture, and the mixture is stirred uniformly and placed in a cool place.
Heating sesame oil to about 50 degrees, adding the angelica sinensis decoction pieces, frying with soft fire until the angelica sinensis decoction pieces turn yellow, adding the lithospermum decoction pieces, frying with soft fire for 20 minutes, completely leaching out the herbal medicines, adding beeswax, stopping heating, slowly stirring, cooling to 40 degrees, adding smashed borneol, stirring uniformly, and placing in a cool place.
Heating oleum Sesami to about 40 deg.C, adding radix Angelicae sinensis decoction pieces, frying with slow fire to brown, adding radix Arnebiae decoction pieces, frying with slow fire for 10 min, draining off the herbs, adding Cera flava, stopping heating, slowly stirring, cooling to 30 deg.C, adding smashed Borneolum, stirring, and standing in cool place.
Heating oleum Sesami to about 60 deg.C, adding radix Angelicae sinensis decoction pieces, frying with slow fire to brown, adding radix Arnebiae decoction pieces, frying with slow fire for 30 min, draining off the herbs, adding Cera flava, stopping heating, slowly stirring, cooling to 50 deg.C, adding smashed Borneolum, stirring, and cooling to cool place.
The following describes the ingredients in combination with the pharmaceutical mechanism:
chinese angelica: promoting blood circulation, dispelling blood stasis, relieving pain, relieving spasm, dilating peripheral blood vessel, and increasing blood circulation.
Lithospermum: clearing heat and cooling blood, promoting blood circulation and relieving swelling, and has inhibiting effect on Pseudomonas aeruginosa and Staphylococcus aureus.
Sesame oil: sweet and cool in nature and flavor, promote tissue regeneration and relieve pain, and eliminate carbuncle and swelling.
Beeswax: resisting bacteria, relieving inflammation, promoting granulation, and relieving pain.
Borneol: clear heat and remove toxicity, promote tissue regeneration and astringe.
The invention has the beneficial effects that: the invention has the advantages that the pure traditional Chinese medicines are adopted, and the compatibility of medicines is utilized to achieve the purposes of clearing heat, relieving pain, removing necrotic tissue and promoting granulation; the medicament has broad-spectrum bacteriostatic and bactericidal effects, particularly has different degrees of inhibiting and killing effects on pseudomonas aeruginosa, staphylococcus, dysentery bacillus, escherichia coli and proteus, and other beneficial effects are detailed in specific embodiments.
Detailed Description
The described embodiments are only a part of the embodiments of the present invention, not all embodiments, and all other embodiments obtained by those skilled in the art without inventive labor based on the embodiments of the present invention belong to the protection scope of the present invention.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs, and the terms used herein are for the purpose of describing particular embodiments only and are not intended to be limiting of the invention, and terms such as "and/or" as used herein include any and all combinations of one or more of the associated listed items; in addition, the technical features involved in the different embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.
Example 1
The externally applied ointment for treating burns and scalds comprises 300-1000 g of angelica sinensis, 100-300 g of lithospermum, 500-1500 g of sesame oil, 20-80 g of beeswax and 20-50 g of borneol, wherein sesame oil is burnt to about 40-60 degrees, angelica sinensis decoction pieces are placed into the sesame oil, the angelica sinensis decoction pieces are fried to be yellow with soft fire, the lithospermum decoction pieces are placed into the sesame oil, the medicine materials are fried for 10-30 minutes with soft fire, all the herbal medicines are drained, the beeswax is placed into the sesame oil, the medicine materials are continuously and slowly stirred with the soft fire, the smashed borneol is placed into the sesame oil after being cooled to 30-50 degrees, and the medicine materials are uniformly stirred and placed in a.
Example 2
The externally-applied ointment for treating burns and scalds comprises 500 g of Chinese angelica, 200 g of lithospermum, 1000 g of sesame oil, 50 g of beeswax and 30 g of borneol, the Chinese angelica decoction pieces are put into the sesame oil after being burnt to about 50 degrees, the lithospermum decoction pieces are put into the sesame oil after being fried to be yellow with small fire, the Chinese lithospermum decoction pieces are fried for 20 minutes with small fire, all the herbal medicines are completely leached out, the beeswax is put into the sesame oil, the mixture is slowly stirred without stopping fire, the smashed borneol is put into the mixture after being cooled to 40 degrees, and the mixture is uniformly stirred and is put.
Example 3
The externally-applied ointment for treating burns and scalds comprises 300 g of Chinese angelica, 100 g of lithospermum, 500 g of sesame oil, 20 g of beeswax and 20 g of borneol, the sesame oil is burnt to about 40 degrees and then put into Chinese angelica decoction pieces, the Chinese angelica decoction pieces are fried to be yellow with small fire and then put into the lithospermum decoction pieces, the Chinese angelica decoction pieces are fried with small fire for 10 minutes, all the herbal medicines are leached out, the beeswax is put into the Chinese angelica decoction pieces, the Chinese angelica decoction pieces are slowly stirred without stopping fire, the Chinese angelica decoction pieces are cooled to 30 degrees, the smashed borneol is added into the Chinese angelica decoction.
Example 4
The externally-applied ointment for treating burns and scalds comprises 1000 g of Chinese angelica, 300 g of lithospermum, 1500 g of sesame oil, 80 g of beeswax and 50 g of borneol, the sesame oil is burnt to about 60 degrees and then put into Chinese angelica decoction pieces, the Chinese angelica decoction pieces are fried to be yellow with soft fire and then put into the lithospermum decoction pieces, the Chinese angelica decoction pieces are fried with soft fire for 30 minutes, all the herbal medicines are completely leached out, the beeswax is put into the Chinese angelica decoction pieces, the Chinese angelica decoction pieces are slowly stirred without stopping the fire, the Chinese angelica decoction pieces are cooled to 50 degrees, the smashed borneol is added into the Chinese.
Example 5
The externally-applied ointment for treating burns and scalds comprises 400 g of Chinese angelica, 150 g of lithospermum, 800 g of sesame oil, 60 g of beeswax and 40 g of borneol, the sesame oil is burnt to about 55 degrees and then put into Chinese angelica decoction pieces, the Chinese angelica decoction pieces are fried to be yellow with small fire and then put into the lithospermum decoction pieces, the Chinese angelica decoction pieces are fried with small fire for 25 minutes, all the herbal medicines are leached out, the beeswax is put into the Chinese angelica decoction pieces, the Chinese angelica decoction pieces are slowly stirred without stopping the fire, the Chinese angelica decoction pieces are cooled to 45 degrees and then added with smashed borneol and stirred evenly.
Example 6
The externally-applied ointment for treating burns and scalds comprises 500 g of Chinese angelica, 200 g of lithospermum, 1000 g of sesame oil, 50 g of beeswax and 30 g of borneol, the sesame oil is burnt to about 40 degrees and then put into Chinese angelica decoction pieces, the Chinese angelica decoction pieces are fried to be yellow with small fire and then put into the lithospermum decoction pieces, the Chinese angelica decoction pieces are fried with small fire for 10 minutes, all the herbal medicines are leached out, the beeswax is put into the Chinese angelica decoction pieces, the Chinese angelica decoction pieces are slowly stirred without stopping fire, the Chinese angelica decoction pieces are cooled to 30 degrees, the smashed borneol is added into the Chinese angelica decoction.
Example 7
The externally-applied ointment for treating burns and scalds comprises 300 g of Chinese angelica, 100 g of lithospermum, 500 g of sesame oil, 20 g of beeswax and 20 g of borneol, the sesame oil is burnt to about 40 degrees and then put into Chinese angelica decoction pieces, the Chinese angelica decoction pieces are fried to be yellow with small fire and then put into the lithospermum decoction pieces, the Chinese angelica decoction pieces are fried with small fire for 10 minutes, all the herbal medicines are leached out, the beeswax is put into the Chinese angelica decoction pieces, the Chinese angelica decoction pieces are slowly stirred without stopping fire, the Chinese angelica decoction pieces are cooled to 30 degrees, the smashed borneol is added into the Chinese angelica decoction.
Example 8
The externally-applied ointment for treating burns and scalds comprises 1000 g of Chinese angelica, 300 g of lithospermum, 1500 g of sesame oil, 80 g of beeswax and 50 g of borneol, the sesame oil is burnt to about 40 degrees and then put into Chinese angelica decoction pieces, the Chinese angelica decoction pieces are fried to be yellow with soft fire and then put into the lithospermum decoction pieces, the Chinese angelica decoction pieces are fried with soft fire for 10 minutes, all the herbal medicines are leached out, the beeswax is put into the Chinese angelica decoction pieces, the Chinese angelica decoction pieces are slowly stirred without stopping the fire, the Chinese angelica decoction pieces are cooled to 30 degrees, the smashed borneol is added into the Chinese angelica.
Examples of cases are:
1. the patients: opening a certain page; male; age 32 years old; because the face is burnt by the caustic soda carelessly during work, the face can be healed after 15 days by using the medicine for treating the burn.
2. The patients: certain of plum; a woman; age 32 years old; the foot and the face are scalded by boiled water, and the burn can be healed after 8 days by using the medicine for treating the burn.
3. The patients: flower certain; a woman; age 25; the scald of the left ear, severe second degree, is healed after 10 days of using the medicine for treating burn of the invention.
4. The patients: opening a certain page; male; age 23; the medicine for treating the burn is not good after four days in a hospital and begins to generate the symptom of the fever because of being carelessly scalded and superficial two degrees, and the medicine for treating the burn is cured after 12 days.
The present invention is further described in the detailed description, rather than by limitation, and it will be apparent to those skilled in the art that numerous changes in structure may be made without departing from the spirit and scope of the invention, all of which are intended to be covered by the appended claims.

Claims (9)

1. An external ointment for treating burns and scalds is characterized in that: the external ointment for treating burns and scalds comprises 300-1000 g of angelica sinensis, 100-300 g of lithospermum, 500-1500 g of sesame oil, 20-80 g of beeswax and 20-50 g of borneol.
2. The external ointment for treating burns and scalds as claimed in claim 1, which is characterized in that: the external ointment for treating burns and scalds comprises 500 g of angelica, 200 g of lithospermum, 1000 g of sesame oil, 50 g of beeswax and 30 g of borneol.
3. The external ointment for treating burns and scalds as claimed in claim 1, which is characterized in that: the external ointment for treating burns and scalds comprises 300 g of angelica, 100 g of lithospermum, 500 g of sesame oil, 20 g of beeswax and 20 g of borneol.
4. The external ointment for treating burns and scalds as claimed in claim 1, which is characterized in that: the external ointment for treating burns and scalds comprises 1000 g of angelica, 300 g of lithospermum, 1500 g of sesame oil, 80 g of beeswax and 50 g of borneol.
5. The external ointment for treating burns and scalds as claimed in claim 1, which is characterized in that: the external ointment for treating burns and scalds comprises 400 g of angelica, 150 g of lithospermum, 800 g of sesame oil, 60 g of beeswax and 40 g of borneol.
6. A process for preparing the ointment for external use for treating burns and scalds according to any one of claims 1 to 5, which is characterized in that: the sesame oil is heated to about 40-60 degrees, the angelica sinensis decoction pieces are placed into the sesame oil, the sesame oil is fried to be yellow with soft fire, the lithospermum decoction pieces are placed into the sesame oil, the sesame oil is fried for 10-30 minutes with soft fire, all the herbal medicines are drained out, the beeswax is placed into the sesame oil, the mixture is slowly stirred without stopping the fire, the mixture is cooled to 30-50 degrees, the smashed borneol is added into the mixture, and the mixture is stirred uniformly and placed in a cool place.
7. The process of claim 6, wherein: heating sesame oil to about 50 degrees, adding the angelica sinensis decoction pieces, frying with soft fire until the angelica sinensis decoction pieces turn yellow, adding the lithospermum decoction pieces, frying with soft fire for 20 minutes, completely leaching out the herbal medicines, adding beeswax, stopping heating, slowly stirring, cooling to 40 degrees, adding smashed borneol, stirring uniformly, and placing in a cool place.
8. The process of claim 6, wherein: heating oleum Sesami to about 40 deg.C, adding radix Angelicae sinensis decoction pieces, frying with slow fire to brown, adding radix Arnebiae decoction pieces, frying with slow fire for 10 min, draining off the herbs, adding Cera flava, stopping heating, slowly stirring, cooling to 30 deg.C, adding smashed Borneolum, stirring, and standing in cool place.
9. The process of claim 6, wherein: heating oleum Sesami to about 60 deg.C, adding radix Angelicae sinensis decoction pieces, frying with slow fire to brown, adding radix Arnebiae decoction pieces, frying with slow fire for 30 min, draining off the herbs, adding Cera flava, stopping heating, slowly stirring, cooling to 50 deg.C, adding smashed Borneolum, stirring, and cooling to cool place.
CN202010058418.3A 2020-01-18 2020-01-18 External ointment for treating burns and scalds Pending CN110934900A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116270835A (en) * 2023-01-08 2023-06-23 管为东 Wound medicine and preparation method and equipment thereof

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CN104758337A (en) * 2015-03-30 2015-07-08 杨思思 Skin externally used traditional Chinese medicine composition and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN1634221A (en) * 2004-09-29 2005-07-06 修宝中 Medicine for treating burns and scalds and its preparation
CN102343006A (en) * 2010-07-30 2012-02-08 李普华 Ointment for treating burns and scalds, and preparation method thereof
CN104758337A (en) * 2015-03-30 2015-07-08 杨思思 Skin externally used traditional Chinese medicine composition and preparation method thereof

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116270835A (en) * 2023-01-08 2023-06-23 管为东 Wound medicine and preparation method and equipment thereof

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Application publication date: 20200331