CN104435383B - It is a kind of to treat burn and scald, the combination ointment of skin injury sore and preparation method - Google Patents

It is a kind of to treat burn and scald, the combination ointment of skin injury sore and preparation method Download PDF

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CN104435383B
CN104435383B CN201410648770.7A CN201410648770A CN104435383B CN 104435383 B CN104435383 B CN 104435383B CN 201410648770 A CN201410648770 A CN 201410648770A CN 104435383 B CN104435383 B CN 104435383B
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obtains
sore
ointment
borneol
scald
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CN104435383A (en
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封大为
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BINYANG COUNTY FENGDAWEI NATIONAL BURNS AND WOUNDS INSTITUTE
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BINYANG COUNTY FENGDAWEI NATIONAL BURNS AND WOUNDS INSTITUTE
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Abstract

A kind of combination ointment for treating burn and scald, skin injury sore and preparation method thereof, includes the following steps：Weight percent weighs raw material, first the chopping of Chinese mahonia 2 5%, yellow avens 0.5 2%, tassel flower 0.5 2%, cherokee rose root 0.5 2%, Gardenia jasminoides ellis 1 2.5%, honeysuckle 1 3%, Radix zanthoxyli 1 2%, giant knotweed 0.5 2% and earthworm 0.5 2% is put into container, then pour into 47 75.7% camellia oils；Then it impregnates, stir, heating simultaneously filter and remove residue；20 30% beeswaxs are added in after being further warming up to 200~220 DEG C and continue infusion；0.5 1.5% borneol powder is added in after cooling, is stirred evenly to get to the combination ointment.Inventive formulation is reasonable, has effects that rapid analgesic, the protection surface of a wound, clearing heat and detoxicating, inhibition infection, promoting blood circulationization corruption, the remaining skin cell tissue of promotion regenerate, accelerate wound healing and prevent scar.

Description

It is a kind of to treat burn and scald, the combination ointment of skin injury sore and preparation method
Technical field
The present invention relates to field of medicaments, specifically a kind of combination ointment and its system for treating burn and scald, skin injury sore Preparation Method.
Background technology
Burn is a kind of common injury, is one of maximum wound of damage property.Surface of a wound pain, infection, necrosis progrediens It is always to perplex the four problems of burn treating with scar healing.There is the drug for much treating this disease both at home and abroad, such drug is each Class is various, but mostly long there are the course for the treatment of, and effect is poor, and pharmaceutical compositions are more, and preparing process is complicated, inconvenient for use, medicament effective component The drawbacks such as slow and expensive are absorbed, increase pain and the financial burden of patient.
Invention content
The purpose of the present invention is to provide it is a kind of protection the surface of a wound, anti-inflammatory analgetic, remove necrosis and promote granulation, it is promoting blood circulation and removing blood stasis and promote it is residual The treatment burn and scald of remaining skin cell tissue's growth, the combination ointment of skin injury sore.Another object of the present invention is to carry For a kind of preparation method for combining ointment for treating burn and scald, skin injury sore, preparation method is simple, and curative effect is reliable and stable.
To achieve these goals, present invention employs following technical schemes：
A kind of combination ointment for treating burn and scald, skin injury sore, is made of the raw material of following weight percent：Ten is big Contribution 2-5%, yellow avens 0.5-2%, tassel flower 0.5-2%, cherokee rose root 0.5-2%, Gardenia jasminoides ellis 1-2.5%, honeysuckle 1- 3%th, Radix zanthoxyli 1-2%, giant knotweed 0.5-2%, earthworm 0.5-2%, camellia oil 47-75.7%, beeswax 20-30% and borneol 0.5- 1.5%, the above components weight percent and for 100%.
A kind of preparation method of combination ointment as described in claim 1, includes the following steps：
(1) raw material is weighed by the weight percent；
(2) borneol that step (1) weighing obtains is broken into powder, obtains borneol powder；
(3) step (1) is weighed into obtained Chinese mahonia, yellow avens, tassel flower, cherokee rose root, Gardenia jasminoides ellis, honeysuckle, two Face needle, giant knotweed and earthworm chopping are put into container, then the camellia oil that step (1) weighing obtains is poured into container, and immersion 10~ It 25 days, is stirred 1-5 times daily in soaking process, obtains soak；
(4) after the soak obtained by step (3) being heated to 130~180 DEG C and keeping the temperature 2~5 hours, filter and remove residue obtains Filtered fluid is impregnated to heating；
(5) heating obtained by step (4) is impregnated addition step (1) weighing after filtered fluid is warming up to 200~220 DEG C to obtain Beeswax, then continue infusion 2~3 hours at a temperature of 200~220 DEG C, obtain infusion medicine slurry；
(6) the infusion medicine slurry obtained by step (5) is naturally cooled to 40~50 DEG C, adds in the borneol powder obtained by step (2) End is stirred evenly and is cooled to room temperature to get to the combination ointment.
The application method of combination ointment of the present invention is external application, after the surface of a wound is cleaned with physiological saline, with the group Close ointment and smear affected part, then wrapped up with sterile gauze, it is daily or the next day dressing it is primary.
Compared with prior art, the advantageous effect that the present invention has：
The present invention selects the exclusive Chinese herbal medicine in Guangxi Mountains and by traditional Chinese medical science sore theory and cooling blood and relieving pain, clearing heat and detoxicating, living Blood stagnation resolvation and the principle of reatment removed necrosis and promoted granulation have been composed the combination ointment.The combination ointment has the protection surface of a wound, disappears Swollen analgesic, clearing heat and detoxicating, antibacterial anti-inflammatory, promoting blood circulationization are rotten, nurse tissue is moistened in Tianjin and the remaining skin cell tissue's regeneration of promotion accelerates The effect of wound healing has good therapeutic effect to burn and scald, skin injury infection, the surface of a wound of long disunion and sore. It is demonstrated experimentally that combination ointment of the present invention is for burning, scalding and wound sore has significant curative effect, more after seldom leave scar Trace.Large-area burns are particularly treated, effect is very good, can protect the surface of a wound, is easy to nurse, and dressing does not stimulate, not sticky, does not go out Blood, pain, does not promote the surface of a wound quickly to heal.Cheap, it is convenient to prepare, and has no toxic side effect.By the clinical verification of more than 20 years Its effective percentage is more than 98%.Combination ointment raw material materials of the present invention are extensive, and formula is rigorous, curative for effect.
Specific embodiment
Raw material used in inventive formulation, using common Chinese herbal medicine, medicine source is enriched, is easy to obtain.It is each in formula The attribute and effect of taste herbal raw material are as follows：
Yellow avens：It is clearing heat and detoxicating, cooling blood and hemostasis.For diseases caused by external factors excess heat polydipsia, abscess of throat, aphtha, jaundice, pyrotoxic dysentery, Chordapsus, swollen ulcer drug, bleeding from five sense organs or subcutaneous tissue, blood strangury and traumatic hemorrhage.
Cherokee rose root：Restrain astringent method, arresting bleeding and treating cutaneous pyogenic infection, interior promoting blood circulation of dispelling, analgesic, disinsection efficiency.
Gardenia jasminoides ellis：Heat-clearing, purging intense heat, cool blood.
Chinese mahonia：There is the effect of clearing heat and detoxicating, detumescence.Have to staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa Good inhibiting effect.
Honeysuckle：Nature and flavor are sweet, tremble with fear.Return lung, stomach, large intestine channel.Effect：It is clearing heat and detoxicating.For ulcer serious case of furuncle, infantile malnutrition due to digestive disturbances or intestinalparasites sore, mange, The diseases such as deep abscess, emphysematous gangrene, late syphilis and exanthemv.
Radix zanthoxyli：It is bitter, pungent, flat, slightly poisonous.Return liver, stomach.Effect：Promoting qi circulation and relieving pain, promoting blood circulation and removing blood stasis, dispelling wind and removing obstruction in the meridians.For Traumatic injury caused by qi depression to blood stasis, arthralgia pain due to rheumatism, stomachache, toothache, venomous snake bite and outer to control soup burning hot.
Tassel flower：Hardship, it is cool.It is clearing heat and detoxicating, eliminating stasis to subdue swelling, cool blood.For sore-throat, oral cavity ulceration, cough due to wind-heat evil, let out It rushes down, dysentery, urine leaching pain, orchitis and epididymitis, acute mastitis and furuncle sore.
Giant knotweed：It is bitter in taste, it trembles with fear.Return liver, courage, lung channel.Effect：Promoting blood circulation analgesic therapy, clearing heat and promoting diuresis removing toxic substances, burn for treatment, Under scald, sore and toxic, venomous snake bite, stranguria with turbid discharge band, anal fistula, the rotten leg of wet sore, impetigo etc..In addition, with significant anti-green pus The effect of bacillus.
Earthworm：Nature and flavor are salty, tremble with fear.Return liver, spleen, bladder warp.Clearing away heat and relieving the wind syndrome is relievingd asthma, dredging collateral, diuresis.It is manic, frightened for high fever Wind twitch, apoplexy and hemiplegia, pant, larynx numbness, bleeding from the gum, scrofula, mumps and sore.Treatment mumps, lower limb are burst Ulcer, erysipelas, herpes zoster, burn and scald etc..
Borneol：Nature and flavor are pungent, bitter, are slightly cold.The thoughts of returning home, spleen, lung channel.Inducing resuscitation of having one's ideas straightened out, clearing away heat to and alleviating pain.For various sores, throat The treatment of the diseases such as swelling and pain, tympanitis, aphtha, carbuncle swells, hemorrhoid, burn, and have clearing away heat to and alleviating pain, anti-corrosion itching-relieving efficacies.
Bee is cured：Inducing astrigency, hemostasis, sore, myogenic relieve pain, conditioning.Outside for unhealing ulcer, ulcer on the shank erosion, wound and burning Scald.
Camellia oil：Cooler, the effect of property：It is clearing heat and detoxicating, antibacterial anti-inflammatory, cooling blood and hemostasis.Camellia oil rich in vitamin E and calcium, The trace elements such as iron, zinc are described as the Zn-ef ficiency of " flowers of life " by physician and nutritionist, and it is very good that regeneration is played Tianjin profit trophism.
Technical scheme of the present invention is further elaborated below by embodiment.
Embodiment 1
A kind of preparation method for combining ointment for treating burn and scald, skin injury sore, includes the following steps：
(1) raw material is weighed by following weight percent：Chinese mahonia 2%, yellow avens 0.5%, tassel flower 0.5%, Jin Ying Root 0.5%, Gardenia jasminoides ellis 1%, honeysuckle 1%, Radix zanthoxyli 1%, giant knotweed 0.5%, earthworm 0.5%, camellia oil 47%, beeswax 20%th, borneol 0.5%, the above components weight percent and for 100%；
(2) borneol that step (1) weighing obtains is broken into powder, obtains borneol powder；
(3) step (1) is weighed into obtained Chinese mahonia, yellow avens, tassel flower, cherokee rose root, Gardenia jasminoides ellis, honeysuckle, two Face needle, giant knotweed and earthworm chopping are put into container, then the camellia oil that step (1) weighing obtains is poured into container, are impregnated 10 days, It is stirred daily in soaking process 2 times, obtains soak；
(4) after the soak obtained by step (3) being heated to 160 DEG C and keeping the temperature 2 hours, filter and remove residue obtains heating leaching Steep filtered fluid；
(5) filtered fluid is impregnated into the heating obtained by step (4) and is warming up to the bee that addition step (1) weighing obtains after 200 DEG C Then wax continues infusion 3 hours at a temperature of 200 DEG C, obtains infusion medicine slurry；
(6) the infusion medicine slurry obtained by step (5) is naturally cooled to 50 DEG C, adds in the borneol powder obtained by step (2), stir It mixes uniformly and is cooled to room temperature to get to the combination ointment.
Embodiment 2
A kind of preparation method for combining ointment for treating burn and scald, skin injury sore, includes the following steps：
(1) raw material is weighed by following weight percent：Chinese mahonia 5%, yellow avens 2%, tassel flower 2%, cherokee rose root 2%th, Gardenia jasminoides ellis 2.5%, honeysuckle 3%, Radix zanthoxyli 2%, giant knotweed 2%, earthworm 2%, camellia oil 72%, beeswax 20%, borneol 0.5%, the above components weight percent and for 100%；
(2) borneol that step (1) weighing obtains is broken into powder, obtains borneol powder；
(3) step (1) is weighed into obtained Chinese mahonia, yellow avens, tassel flower, cherokee rose root, Gardenia jasminoides ellis, honeysuckle, two Face needle, giant knotweed and earthworm chopping are put into container, then the camellia oil that step (1) weighing obtains is poured into container, are impregnated 12 days, It is stirred daily in soaking process 3 times, obtains soak；
(4) after the soak obtained by step (3) being heated to 165 DEG C and keeping the temperature 2.5 hours, filter and remove residue is heated Impregnate filtered fluid；
(5) filtered fluid is impregnated into the heating obtained by step (4) and is warming up to the bee that addition step (1) weighing obtains after 205 DEG C Then wax continues infusion 2.5 hours at a temperature of 205 DEG C, obtains infusion medicine slurry；
(6) the infusion medicine slurry obtained by step (5) is naturally cooled to 45 DEG C, adds in the borneol powder obtained by step (2), stir It mixes uniformly and is cooled to room temperature to get to the combination ointment.
Embodiment 3
A kind of preparation method for combining ointment for treating burn and scald, skin injury sore, includes the following steps：
(1) raw material is weighed by following weight percent：Chinese mahonia 3%, yellow avens 1%, tassel flower 0.5%, cherokee rose root 1%th, Gardenia jasminoides ellis 1%, honeysuckle 2%, Radix zanthoxyli 1.5%, giant knotweed 0.5%, earthworm 1%, camellia oil 62.5%, beeswax 25%, Borneol 1%, the above components weight percent and for 100%；
(2) borneol that step (1) weighing obtains is broken into powder, obtains borneol powder；
(3) step (1) is weighed into obtained Chinese mahonia, yellow avens, tassel flower, cherokee rose root, Gardenia jasminoides ellis, honeysuckle, two Face needle, giant knotweed and earthworm chopping are put into container, then the camellia oil that step (1) weighing obtains is poured into container, impregnate 15 My god, it is stirred daily in soaking process 4 times, obtains soak；
(4) after the soak obtained by step (3) being heated to 170 DEG C and keeping the temperature 3.5 hours, filter and remove residue is heated Impregnate filtered fluid；
(5) filtered fluid is impregnated into the heating obtained by step (4) and is warming up to the bee that addition step (1) weighing obtains after 210 DEG C Then wax continues infusion 2 hours at a temperature of 210 DEG C, obtains infusion medicine slurry；
(6) the infusion medicine slurry obtained by step (5) is naturally cooled to 40 DEG C, adds in the borneol powder obtained by step (2), stir It mixes uniformly and is cooled to room temperature to get to the combination ointment.
Embodiment 4
A kind of preparation method for combining ointment for treating burn and scald, skin injury sore, includes the following steps：
(1) raw material is weighed by following weight percent：Chinese mahonia 4%, yellow avens 0.75%, tassel flower 1%, cherokee rose root 1.5%th, Gardenia jasminoides ellis 1.5%, honeysuckle 1.5%, Radix zanthoxyli 1%, giant knotweed 1.5%, earthworm 1.5%, camellia oil 63.25%, bee Wax 22%, borneol 0.5%, the above components weight percent and for 100%；
(2) borneol that step (1) weighing obtains is broken into powder, obtains borneol powder；
(3) step (1) is weighed into obtained Chinese mahonia, yellow avens, tassel flower, cherokee rose root, Gardenia jasminoides ellis, honeysuckle, two Face needle, giant knotweed and earthworm chopping are put into container, then the camellia oil that step (1) weighing obtains is poured into container, are impregnated 23 days, It is stirred daily in soaking process 2 times, obtains soak；
(4) after the soak obtained by step (3) being heated to 180 DEG C and keeping the temperature 4 hours, filter and remove residue obtains heating leaching Steep filtered fluid；
(5) filtered fluid is impregnated into the heating obtained by step (4) and is warming up to the bee that addition step (1) weighing obtains after 200 DEG C Then wax continues infusion 3 hours at a temperature of 200 DEG C, obtains infusion medicine slurry；
(6) the infusion medicine slurry obtained by step (5) is naturally cooled to 43 DEG C, adds in the borneol powder obtained by step (2), stir It mixes uniformly and is cooled to room temperature to get to the combination ointment.
Embodiment 5
A kind of preparation method for combining ointment for treating burn and scald, skin injury sore, includes the following steps：
(1) raw material is weighed by following weight percent：Chinese mahonia 2%, yellow avens 1.5%, tassel flower 1.5%, Jin Ying Root 1%, Gardenia jasminoides ellis 2%, honeysuckle 2.5%, Radix zanthoxyli 2%, giant knotweed 1%, earthworm 1%, camellia oil 57.5%, beeswax 27%, Borneol 1%, the above components weight percent and for 100%；
(2) borneol that step (1) weighing obtains is broken into powder, obtains borneol powder；
(3) step (1) is weighed into obtained Chinese mahonia, yellow avens, tassel flower, cherokee rose root, Gardenia jasminoides ellis, honeysuckle, two Face needle, giant knotweed and earthworm chopping are put into container, then the camellia oil that step (1) weighing obtains is poured into container, are impregnated 18 days, It is stirred daily in soaking process 4 times, obtains soak；
(4) after the soak obtained by step (3) being heated to 150 DEG C and keeping the temperature 5 hours, filter and remove residue obtains heating leaching Steep filtered fluid；
(5) filtered fluid is impregnated into the heating obtained by step (4) and is warming up to the bee that addition step (1) weighing obtains after 215 DEG C Then wax continues infusion 2 hours at a temperature of 215 DEG C, obtains infusion medicine slurry；
(6) the infusion medicine slurry obtained by step (5) is naturally cooled to 48 DEG C, adds in the borneol powder obtained by step (2), stir It mixes uniformly and is cooled to room temperature to get to the combination ointment.
Embodiment 6
A kind of preparation method for combining ointment for treating burn and scald, skin injury sore, includes the following steps：
(1) raw material is weighed by following weight percent：Chinese mahonia 3%, yellow avens 2%, tassel flower 1%, cherokee rose root 0.5%th, Gardenia jasminoides ellis 1.5%, honeysuckle 2%, Radix zanthoxyli 1.5%, giant knotweed 0.5%, earthworm 2%, camellia oil 56.5%, beeswax 28%th, borneol 1.5%, the above components weight percent and for 100%；
(2) borneol that step (1) weighing obtains is broken into powder, obtains borneol powder；
(3) step (1) is weighed into obtained Chinese mahonia, yellow avens, tassel flower, cherokee rose root, Gardenia jasminoides ellis, honeysuckle, two Face needle, giant knotweed and earthworm chopping are put into container, then the camellia oil that step (1) weighing obtains is poured into container, are impregnated 20 days, It is stirred daily in soaking process 5 times, obtains soak；
(4) after the soak obtained by step (3) being heated to 180 DEG C and keeping the temperature 2~5 hours, filter and remove residue is heated Impregnate filtered fluid；
(5) filtered fluid is impregnated into the heating obtained by step (4) and is warming up to the bee that addition step (1) weighing obtains after 210 DEG C Then wax continues infusion 2.5 hours at a temperature of 210 DEG C, obtains infusion medicine slurry；
(6) the infusion medicine slurry obtained by step (5) is naturally cooled to 45 DEG C, adds in the borneol powder obtained by step (2), stir It mixes uniformly and is cooled to room temperature to get to the combination ointment.
Model case explanation：
Case 1：Guangxi Binyang County Jiang XX, man, 56 years old.In June, 2008 by about 45% area of gunpowder burns whole body many places, In second-degree burn.The surface of a wound is cleaned up with physiological saline, disinfecting cotton swab is smeared is applied to the surface of a wound by combination ointment of the present invention Gauze is wrapped up, and daily dressing is primary, is fully recovered within 22 days, is not stayed scar.
Case 2：The small Pingyang town Huang XX of Laibin, Guangxi Province, man, 42 years old.In May, 2010 by petrol burn Head And Face, shirtfront and Double upper limbs, burn surface area 30% is two degree deep, three degree of part, abrasion, and base is low red and white.It is with physiological saline that the surface of a wound is clear Wash clean, disinfecting cotton swab is smeared is applied to the wrapping of surface of a wound gauze by combination ointment of the present invention, fully recovers within 28 days.
Case 3：Guangxi Shang Lin Zhen Long townshiies Lee XX, in September, 2012 is by flame burn whole body many places, area about 60%, wherein Shallow two degree account for 25%, and deep two degree account for 28%, and three degree account for 7%, and epidermis all strips off, and base is low red and white, and double forearm parts are in skin Leather, hypovolemic shock.It is anti-infectious simultaneously to give fluid infusion Hemorrhagic shock, is cleaned up the surface of a wound with physiological saline, aseptic cotton Label are smeared is applied to the wrapping of surface of a wound gauze by combination ointment of the present invention, and daily dressing is primary, recovery from illness discharge in 36 days.
Case 4：Guangxi Binyang bridge town clock XX, female, 62 years old.Suffer from outside 6 years right lower extremity shanks of diabetes then exanthemv 3 Year, go to our hospital's treatment in April, 2013, about 5% area of the surface of a wound festers and suppurates.The surface of a wound is cleaned up with physiological saline, is sterilized Cotton swab smear by it is of the present invention combination ointment be applied to the surface of a wound gauze wrapping, the next day dressing it is primary, 56 days fully recover.
Case 5：Guangxi Binyang Binzhou town land XX, man, 6 years old.In July, 2013 is fallen into the bucket for filling boiling water accidentally, until stern Portion and both thighs scald, area about 15%, two degree.Abrasion, base are low red and white.After being admitted to hospital, with physiological saline by the surface of a wound It cleans up, disinfecting cotton swab is smeared is applied to the wrapping of surface of a wound gauze by combination ointment of the present invention, and daily dressing is primary, creates within 15 days All recovery from illness does not leave apparent scar in face.

Claims (2)

1. a kind of combination ointment for treating burn and scald, skin injury sore, which is characterized in that by the raw material of following weight percent It is made：Chinese mahonia 2-5%, yellow avens 0.5-2%, tassel flower 0.5-2%, cherokee rose root 0.5-2%, Gardenia jasminoides ellis 1-2.5%, gold Honeysuckle flower 1-3%, Radix zanthoxyli 1-2%, giant knotweed 0.5-2%, earthworm 0.5-2%, camellia oil 47-75.7%, beeswax 20-30% and ice Piece 0.5-1.5%, the above components weight percent and for 100%.
2. a kind of preparation method of combination ointment as described in claim 1, which is characterized in that include the following steps：
(1) raw material is weighed by the weight percent；
(2) borneol that step (1) weighing obtains is broken into powder, obtains borneol powder；
(3) by step (1) weighing obtain Chinese mahonia, yellow avens, tassel flower, cherokee rose root, Gardenia jasminoides ellis, honeysuckle, Radix zanthoxyli, Giant knotweed and earthworm chopping are put into container, then the camellia oil that step (1) weighing obtains is poured into container, are impregnated 10~25 days, It is stirred 1-5 times daily in soaking process, obtains soak；
(4) after the soak obtained by step (3) being heated to 130~180 DEG C and keeping the temperature 2~5 hours, filter and remove residue is added Heat soaking filtered fluid；
(5) filtered fluid is impregnated into the heating obtained by step (4) and is warming up to the bee that addition step (1) weighing obtains after 200~220 DEG C Then wax continues infusion 2~3 hours at a temperature of 200~220 DEG C, obtains infusion medicine slurry；
(6) the infusion medicine slurry obtained by step (5) is naturally cooled to 40~50 DEG C, adds in the borneol powder obtained by step (2), stir It mixes uniformly and is cooled to room temperature to get to the combination ointment.
CN201410648770.7A 2014-11-14 2014-11-14 It is a kind of to treat burn and scald, the combination ointment of skin injury sore and preparation method Expired - Fee Related CN104435383B (en)

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