CN103223061B - External application bedsore drug and preparation method thereof - Google Patents

External application bedsore drug and preparation method thereof Download PDF

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CN103223061B
CN103223061B CN201310154385.2A CN201310154385A CN103223061B CN 103223061 B CN103223061 B CN 103223061B CN 201310154385 A CN201310154385 A CN 201310154385A CN 103223061 B CN103223061 B CN 103223061B
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radix
root
herba
propolis
medicine
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CN103223061A (en
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秦晓飞
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Abstract

The present invention discloses an external application bedsore drug, which is prepared from the following raw materials: 20-35 g of drynaria, 15-30 g of euphorbia humifusa, 100-120 g of longleaf garden burnet root, 50-70 g of amur corktree bark, 90-115 g of propolis, 20-35 g of kalopanax septemlobus root, 15-25 g of coptis chinensis, 15-20 g of licorice root, 9-13 g of largeleaf gentian root, 3-5 g of kusnezoff monkshood mother root (processed), 15-30 g of linear stonecrop herb, 10-25 g of upright ladybell root, 30-50 g of baikal skullcap root, 30-60 g of nakedflower beautyberry branchlet and leaf, 15-25 g of syzygium buxifolium hook, 15-20 g of humus flava usta, 30-50 g of kweiyang betony herb or root, 10-25 g of vaiante spleenwort herb, 15-30 g of tree peony root bark, 3-6 g of borneol, 25-45 g of harlequin glorybower root, 10-20 g of bigfruit phymatopsis herb, 9-15 g of purpleflower holly fruit, 10-15 g of eucalyptus globules, 15-30 g of cairo morningglory root or leaf, 15-25 g of cudweed herb, 25-50 g of ass-hide gelatin, and 3000 ml of 50-65% alcohol.

Description

A kind of decubital ulcer medicine for external use and preparation method thereof
Technical field
The present invention relates to medicine, is a kind of decubital ulcer medicine for external use and preparation method thereof.
Background technology
Decubital ulcer is the ulcer of the skin histology of patient between body surface bone knuckle and bedding.Decubital ulcer is common in long-term bedridden patients.Reason is, patient's muscle power extremely feeble, without force transformation clinostatism, causes skin histology because of continuous compression, local anoxia, and blood vessel embolism, tissue necrosis are rotten de-.The multiple position of decubital ulcer is that rumpbone, ischial tuberosity, greater trochanter of femur etc. are located, and is secondly the positions such as calcaneus, occipital bone, anterior superior iliac spine, medial and lateral malleolus.Its forming process is divided into erythema phase, blister phase and three phases of ulcerative stage.Erythema and blister phase can treat with infrared ray radiation.Table fester can be put Gentian Violet on the skin.Can only excision when deep ulcer can not spontaneous recovery, in row, thick skin-grafting or flap, muscle flap, musculo cutaneous flap shift and repair.But, facts have proved infrared ray radiation treatment or put the therapeutic effect of Gentian Violet on the skin poor, patient's decubital ulcer often develops into the situation that deep ulcer can not spontaneous recovery, has to implement operation, brings great misery, and may jeopardize patient's life security to patient.
Summary of the invention
The object of the invention is, a kind of decubital ulcer medicine for external use and preparation method thereof is provided, it cures mainly the ruddy phase of congestion and inflammatory is invaded the decubital ulcer of profit phase, and the decubital ulcer of ulcerative stage is also had to good curative effect.It has easy to use, and wound surface incrustation is fast, anti-inflammation, and analgesic effect is strong, and granulation promoting is held back wound, and rotten meat is lost in evacuation of pus, and minimizing is oozed out, and promotes effect of tissue regeneration and accelerating wound healing, can play the effect of blood circulation promoting with prevention decubital ulcer.It is also applicable to once to dark two degree burn and scald.
The present invention for achieving the above object, be achieved through the following technical solutions: a kind of decubital ulcer medicine for external use, it is made up of following raw material: Rhizoma Drynariae 20-35g, Radix seu Caulis Parthenocissi tricuspidatae 15-30g, Radix Sanguisorbae 100-120g, Cortex Phellodendri 50-70g, propolis 90-115g, Radix Kalopanacis 20-35g, Rhizoma Coptidis 15-25g, Radix Glycyrrhizae 15-20g, Radix Gentianae Macrophyllae 9-13g, Radix Aconiti Kusnezoffii 3-5g(big gun), Herba Sedi Linearis 15-30g, Radix Adenophorae (Radix Glehniae) 10-25g, Radix Scutellariae 30-50g, Folium et Ramulus Callicarpae nudiflorae 30-60g, Radix Syzygii Buxifolii 15-25g, Terra Flava Usta 15-20g, Herba stachydis kouyangensis 30-50g, Herba Asplenii Vaiainte Spleenwort 10-25g, Cortex Moutan 15-30g, Borneolum Syntheticum 3-6g, Hibisci Mutabilis root 25-45g, Phymatopsis griffithiana (Hook.) J. Sm. 10-20g, Fructus Ilicis Purpureae 9-15g, Eucalyptus globulus Labill 10-15g, Herba Ipomoeae Cairicae 15-30g, common mouse ear 15-25g, Colla Corii Asini 25-50g and 50%-65% ethanol 3000ml.
It will be made up of following raw material: Rhizoma Drynariae 20g, Radix seu Caulis Parthenocissi tricuspidatae 20g, Radix Sanguisorbae 120g, Cortex Phellodendri 70g, propolis 100g, Radix Kalopanacis 30g, Rhizoma Coptidis 15g, Radix Glycyrrhizae 15g, Radix Gentianae Macrophyllae 9g, Radix Aconiti Kusnezoffii 3g(big gun), Herba Sedi Linearis 15g, Radix Adenophorae (Radix Glehniae) 10g, Radix Scutellariae 30g, Folium et Ramulus Callicarpae nudiflorae 50g, Radix Syzygii Buxifolii 15g, Terra Flava Usta 15g, Herba stachydis kouyangensis 30g, Herba Asplenii Vaiainte Spleenwort 10g, Cortex Moutan 20g, Borneolum Syntheticum 6g, Hibisci Mutabilis root 30g, Phymatopsis griffithiana (Hook.) J. Sm. 10g, Fructus Ilicis Purpureae 9g, Eucalyptus globulus Labill 15g, Herba Ipomoeae Cairicae 150g, common mouse ear 25g, Colla Corii Asini 25g and 50% ethanol 3000ml.
The percentage ratio of ethanol of the present invention is percent by volume.
A preparation method for decubital ulcer medicine for external use, is characterized in that:
1. step, gets propolis and Colla Corii Asini by above-mentioned weight ratio, under-18 degree environment, takes out after freezing 6-8 hour, puts into reducing mechanism and is ground into the granule that particle diameter is 1-3mm, pours in the 50%-65% alcoholic solution of 3000ml and soaks; In immersion process, shake up 2-3 every day, each 3-5 minute; Soak and within least 7 days, get supernatant;
2. step is got other raw materials except propolis, Colla Corii Asini and ethanol by above-mentioned weight ratio and is put into reducing mechanism and be ground into the granule that particle diameter is 1-3mm, pouring step into 1. soaks in described supernatant and within 10-15 days, makes medicine liquid mixture, medicine liquid mixture is obtained to medicinal liquid after squeezing filter device squeezing, filtration, medicine liquid irrigation is packed in spray bottle and can be used.Whole preparation process at room temperature completes, and temperature is about 20 degree.
Described reducing mechanism is the large-scale pulverizer of 30B.Described squeezing filter device is the concentrated pressure filter of 800 molding box formulas.
Wherein Rhizoma Drynariae cures mainly malignant boil, loses rotten meat.Radix seu Caulis Parthenocissi tricuspidatae has carbuncle sore tumefacting virus, effect of ulcer being unable to heal.Cortex Phellodendri has effect of antibacterial sore swollen toxin.Radix Sanguisorbae has removing heat from blood, heat-clearing and toxic substances removing, effect of carbuncle gold wound.Propolis has antiinflammatory, sterilization, effect of promotion tissue regeneration.Radix Kalopanacis has removing heat from blood, removing toxic substances and promoting subsidence of swelling, dissipating blood stasis, dispelling wind for relieving itching, effect of dehumidifying; Cure mainly hemorrhoidal hamorrhage hemorrhoidal bleeding, traumatic injury, rheumatic ostalgia, anus is de-, hemorrhoid, skin infection swells and ache or diabrosis.Rhizoma Coptidis has sterilization, and effect of antiinflammatory, cures mainly skin sore.Radix Glycyrrhizae cures mainly carbuncle sore tumefacting virus, cushion toxicity.Radix Gentianae Macrophyllae cures mainly wound discord.Radix Aconiti Kusnezoffii has pain relieving, antibacterial effect.Herba Sedi Linearis has heat clearing away, and effect of removing toxic substances is scalded in detumescence.Radix Adenophorae (Radix Glehniae): analgesia, antifungal.Radix Scutellariae: skin infection evacuation of pus.Suppurative skin ulcer; Folium et Ramulus Callicarpae nudiflorae has hemostasis, antiinflammatory, and blood stasis dispelling, effect of pain relieving,, thrombocytopenic purpura, hematuria, wound hemorrhage, influenza, burn, suppurative skin ulcer, cervical erosion, traumatic injury, rheumatalgia.Radix Syzygii Buxifolii has invigorating spleen to remove dampness, relievings asthma, and effect of dissipating blood stasis for subsidence of swelling, treating edema, children's's asthma induced by eating salt, traumatic injury, dissipating blood stasis for subsidence of swelling, burn due to hot liquid or fire, finger skin ulcer.Terra Flava Usta: warming middle-JIAO dampness, carbuncle ulcer.Herba stachydis kouyangensis energy heat-clearing and toxic substances removing, for furuncle and phyma, pyogenic infection of the bone, anti-inflammation detumescence, evacuation of pus.Cure mainly furuncle, osteomyelitis.Herba Asplenii Vaiainte Spleenwort: promoting blood circulation and detumescence; Hemostasia and promoting granulation, skin infection festers; Burn and scald; Cure mainly knife injury; Fracture; Skin infection festers; Burn and scald.Cortex Moutan: clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, carbuncle sore tumefacting virus.Borneolum Syntheticum: clearing away heat to alleviate pain.Hibisci Mutabilis root also claims Radix Hibisci Mutabilis: heat clearing and damp drying, relieving cough and resolving phlegm.Cure mainly carbuncle, tinea alba, ecthyma, cough and asthma, women leucorrhea.Phymatopsis griffithiana (Hook.) J. Sm.: clearing away heat and cooling blood; Removing toxic substances and promoting subsidence of swelling; Cure mainly carbuncle and ulcer, toxic swelling, scrofula, malignant boil, sudden and violent red acute catarrhal conjunctivitis, gonorrhea, hemorrhoidal hamorrhage.Fructus Ilicis Purpureae: wound is held back in hemostasis, and ulcer being unable to heal, dispels the wind, and effect of tonify deficiency cures mainly rheumatic arthralgia and hemorrhoid.Eucalyptus globulus Labill also claims Folium eucalypti globueli (Eucalyptus globulus Labill.): dispelling wind is antipyretic, inhibiting bacteria and diminishing inflammation, and anticorrosion antipruritic external is controlled and is burnt soup wound, cellulitis skin degerming; Have relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, effect of heat-clearing and toxic substances removing, cures mainly flu, influenza, and dysentery, enteritis, arthralgia, cystitis, scalds scabies, erysipelas, neurodermatitis, eczema, carbuncle pyogenic infections from tumour or sore.Five Dragons pawl: expelling wind and removing dampness, removing blood stasis to reduce swelling, controls carbuncle wound scrofula.Common mouse ear, carbuncle and ulcer, cures mainly furuncle, abscess of testis, hemorrhoid, scald, and control non-infectious ulcer and wound.Colla Corii Asini: external, skin infection ulceration, decubital ulcer infection is prolonged does not hold back.50% ethanol: blood circulation promoting, prevention decubital ulcer occurs.
Chinese medicine primary treatment decubital ulcer of the present invention.The symptom of decubital ulcer:
Erythema phase decubital ulcer (ruddy phase of congestion): the compression zone position of whole body shows as local stasis of blood, and skin presents erythema.If this changes disappearance in 48 hours to remove pressure in this phase.Typical characteristic: " red, swollen, hot, pain or numb continues not take off for 30 minutes " be the non-fading localized erythema with pressure in the skin complete at bone knuckle place.
Blister phase decubital ulcer: the blister differing in size appears in pressurized position, skin rubefaction hyperemia, does not disappear while pressure with finger.Typical characteristic: inflammatory infiltration phase---" purplish red, scleroma, pain, blister ", corium excalation, shows as a shallow open ulcer, with peach wound bed, without slough, also may show as a serum vesicle complete or that break.
Bed sore at ulcerative stage: epidermis breakage, ulcer, ulcer is no more than skin holostrome, because ulcer basilar part lacks blood supply, is pale asphyxia, granulation edema, flowing water is more than.Typical characteristic: holostrome skin histology disappearance, visible subcutaneous fat exposes, but bone, tendon, muscle do not expose, and have slough to exist, but the degree of depth of tissue disappearance is indefinite, may include and move under water and tunnel.
Treat 219 examples, male's 121 examples, women's 98 examples, not etc., age minimum is not 35 years old to 2-5, is 83 years old to the maximum.Treatment criterion: 1, cure: eliminate localized erythema or ulcer surface healing; 2, effective: wound surface is no longer expanded, wound surface is formed a scab or wound inflammation alleviates, and granulation tissue hyperplasia is obvious.Therapeutic Method: every day 3-6 time, at every turn at affected part spraying 1-2ml; Need use asepsis injector teasing blister epidermis that the liquid oozing out is emitted if any blister person, not destroy as far as possible blister epidermis, can make like this medicine infiltration skin can reduce wound surface again and be subject to the invasion and attack of antibacterial.Twice at least 3 hours medication interval time.
Clinical statistics is summed up: treatment erythema phase patients with bedsore has 87 examples, and medication starts effective after 8 hours, and wound surface is no longer expanded, and 12 hours effective percentage of medication are 100%, within medication 1-3 days, eliminates localized erythema, and cure rate is about 100%, and consolidating medication can drug withdrawal after 1 day; Treatment blister phase patients with bedsore has 71 examples, and medication starts effective for 1 day, wound surface incrustation, and the wound surface incrustation of skin ulceration is faster, and medication 1-3 days effective percentage is 100%, medication 10-15 days, cure rate is 98%, consolidates medication drug withdrawal after 1 day; Treatment bed sore at ulcerative stage patient totally 61 examples, medication starts effective for 6 days, and wound inflammation alleviates, and granulation tissue hyperplasia is obvious, and 10 days effective percentage of medication are 100%, medication 15-30 days, cure rate is 96%, consolidates medication drug withdrawal in 3 days.
Model case:
Zhao XX, man, 77 years old, Linqing City people, lies in bed after apoplexy 3 years, because patient household lacks special and professional care knowledge, and nursing limited time, therefore, the many places skin of patient's ischial tuberosity and greater trochanter of femur suffers from bed sore at ulcerative stage, and calcaneus place skin suffers from the skin at erythema phase decubital ulcer, occipital bone place and suffers from blister phase decubital ulcer.Use medicinal liquid of the present invention to start after 12 hours effective, the wound surface of calcaneus place skin is no longer expanded; After medication 1 day, the blister wound surface of occipital bone place skin starts incrustation; After medication 2 days, the localized erythema of calcaneus place skin disappears; After medication 3 days, the skin drug withdrawal of calcaneus place, the skin at occipital bone, ischial tuberosity and greater trochanter of femur place continues medication; After medication 7 days, the wound inflammation of ischial tuberosity and greater trochanter of femur place skin alleviates, and granulation tissue hyperplasia is obvious; After medication 26 days, the wound healing of occipital bone place skin, the skin ulcer face healing at ischial tuberosity and greater trochanter of femur place; Medication drug withdrawal after 33 days.
Points for attention: 1 avoids green onion, ginger and garlic maror, soy sauce, vinegar and seafood; In 2 medication processes, forbid that wound surface gets wet and imitate together drug combination with other; Within after 3 skin healings 48--72 hour, forbid ultraviolet direct irradiation. 
Chinese medicine of the present invention also can be treated burn and scald.Burn and scald refers to that liquid, solid, gas and the electric current etc. of comburant and Shuo heat directly act on human body, cause that skin is scalded or burn, even fire-toxin inside fire attack internal organs, often accompany flushing edema, surface is oozed out in a large number, and taking injury, red and swollen causalgia, foaming, coking crust are the damage class disease of main manifestations.The lighter undermines fur, very injures in muscle muscle severe patient, inside fire attack internal organs and raw all diseases.Burn and scald usage: every day 6-8 time, at every turn at affected part spraying 1-3ml.Once burn and scald medication heals for 1-3 days, and two degree burn and scald medications heal for 7-10 days, and dark two degree burn and scald medications heal for 10-15 days, and 15-20 days surrounding tissue hypertrophy part wound healings of three degree burn and scald medications, can stay slight cicatrix.
Detailed description of the invention
Embodiment:
The raw material of a kind of decubital ulcer medicine for external use of the present invention can have following multiple weight ratio combination:
1, Rhizoma Drynariae 35g, Radix seu Caulis Parthenocissi tricuspidatae 15g, Radix Sanguisorbae 105g, Cortex Phellodendri 63g, propolis 115g, Radix Kalopanacis 20g, Rhizoma Coptidis 18g, Radix Glycyrrhizae 16g, Radix Gentianae Macrophyllae 9g, Radix Aconiti Kusnezoffii 3(big gun), Herba Sedi Linearis 17g, Radix Adenophorae (Radix Glehniae) 15g, Radix Scutellariae 33g, Folium et Ramulus Callicarpae nudiflorae 30g, Radix Syzygii Buxifolii 22g, Terra Flava Usta 19g, Herba stachydis kouyangensis 32g, Herba Asplenii Vaiainte Spleenwort 11g, Cortex Moutan 15g, Borneolum Syntheticum 3g, Hibisci Mutabilis root 25g, Phymatopsis griffithiana (Hook.) J. Sm. 11g, Fructus Ilicis Purpureae 10g, Eucalyptus globulus Labill 10g, Herba Ipomoeae Cairicae 18g, common mouse ear 15g, Colla Corii Asini 25g and 53% ethanol 3000ml.
2, Rhizoma Drynariae 23g, Radix seu Caulis Parthenocissi tricuspidatae 22g, Radix Sanguisorbae 115g, Cortex Phellodendri 65g, propolis 90g, Radix Kalopanacis 35g, Rhizoma Coptidis 25g, Radix Glycyrrhizae 20g, Radix Gentianae Macrophyllae 13g, Radix Aconiti Kusnezoffii 5g(big gun), Herba Sedi Linearis 30g, Radix Adenophorae (Radix Glehniae) 25g, Radix Scutellariae 50g, Folium et Ramulus Callicarpae nudiflorae 60g, Radix Syzygii Buxifolii 25g, Terra Flava Usta 20g, Herba stachydis kouyangensis 50g, Herba Asplenii Vaiainte Spleenwort 25g, Cortex Moutan 30g, Borneolum Syntheticum 6g, Hibisci Mutabilis root 45g, Phymatopsis griffithiana (Hook.) J. Sm. 20g, Fructus Ilicis Purpureae 15g, Eucalyptus globulus Labill 11g, Herba Ipomoeae Cairicae 30g, common mouse ear 20g, Colla Corii Asini 50g and 65% ethanol 3000ml.
3, Rhizoma Drynariae 27g, Radix seu Caulis Parthenocissi tricuspidatae 30g, Radix Sanguisorbae 112g, Cortex Phellodendri 55g, propolis 105g, Radix Kalopanacis 28g, Rhizoma Coptidis 21g, Radix Glycyrrhizae 18g, Radix Gentianae Macrophyllae 11g, Radix Aconiti Kusnezoffii 4g(big gun), Herba Sedi Linearis 23g, Radix Adenophorae (Radix Glehniae) 17g, Radix Scutellariae 40g, Folium et Ramulus Callicarpae nudiflorae 45g, Radix Syzygii Buxifolii 24g, Terra Flava Usta 17g, Herba stachydis kouyangensis 40g, Herba Asplenii Vaiainte Spleenwort 18g, Cortex Moutan 22g, Borneolum Syntheticum 5g, Hibisci Mutabilis root 35g, Phymatopsis griffithiana (Hook.) J. Sm. 15g, Fructus Ilicis Purpureae 12g, Eucalyptus globulus Labill 13g, Herba Ipomoeae Cairicae 23g, common mouse ear 21g, Colla Corii Asini 35g and 57% ethanol 3000ml.
4, Rhizoma Drynariae 20g, Radix seu Caulis Parthenocissi tricuspidatae 20g, Radix Sanguisorbae 120g, Cortex Phellodendri 70g, propolis 100g, Radix Kalopanacis 30g, Rhizoma Coptidis 15g, Radix Glycyrrhizae 15g, Radix Gentianae Macrophyllae 9g, Radix Aconiti Kusnezoffii 3g(big gun), Herba Sedi Linearis 15g, Radix Adenophorae (Radix Glehniae) 10g, Radix Scutellariae 30g, Folium et Ramulus Callicarpae nudiflorae 50g, Radix Syzygii Buxifolii 15g, Terra Flava Usta 15g, Herba stachydis kouyangensis 30g, Herba Asplenii Vaiainte Spleenwort 10g, Cortex Moutan 20g, Borneolum Syntheticum 6g, Hibisci Mutabilis root 30g, Phymatopsis griffithiana (Hook.) J. Sm. 10g, Fructus Ilicis Purpureae 9g, Eucalyptus globulus Labill 15g, Herba Ipomoeae Cairicae 15g, common mouse ear 25g, Colla Corii Asini 40g and 50% ethanol 3000ml.
5, Rhizoma Drynariae 30g, Radix seu Caulis Parthenocissi tricuspidatae 18g, Radix Sanguisorbae 100g, Cortex Phellodendri 50g, propolis 110g, Radix Kalopanacis 33g, Rhizoma Coptidis 17g, Radix Glycyrrhizae 17g, Radix Gentianae Macrophyllae 12g, Radix Aconiti Kusnezoffii 3g(big gun), Herba Sedi Linearis 25g, Radix Adenophorae (Radix Glehniae) 18g, Radix Scutellariae 35g, Folium et Ramulus Callicarpae nudiflorae 40g, Radix Syzygii Buxifolii 20g, Terra Flava Usta 18g, Herba stachydis kouyangensis 45g, Herba Asplenii Vaiainte Spleenwort 15g, Cortex Moutan 18g, Borneolum Syntheticum 4g, Hibisci Mutabilis root 27g, Phymatopsis griffithiana (Hook.) J. Sm. 17g, Fructus Ilicis Purpureae 11g, Eucalyptus globulus Labill 12g, Herba Ipomoeae Cairicae 20g, common mouse ear 22g, Colla Corii Asini 30g and 55% ethanol 3000ml.
6, Rhizoma Drynariae 25g, Radix seu Caulis Parthenocissi tricuspidatae 25g, Radix Sanguisorbae 110g, Cortex Phellodendri 60g, propolis 95g, Radix Kalopanacis 25g, Rhizoma Coptidis 20g, Radix Glycyrrhizae 19g, Radix Gentianae Macrophyllae 10g, Radix Aconiti Kusnezoffii 3g(big gun), Herba Sedi Linearis 20g, Radix Adenophorae (Radix Glehniae) 20g, Radix Scutellariae 45g, Folium et Ramulus Callicarpae nudiflorae 35g, Radix Syzygii Buxifolii 18g, Terra Flava Usta 16g, Herba stachydis kouyangensis 35g, Herba Asplenii Vaiainte Spleenwort 20g, Cortex Moutan 25g, Borneolum Syntheticum 3g, Hibisci Mutabilis root 40g, Phymatopsis griffithiana (Hook.) J. Sm. 13g, Fructus Ilicis Purpureae 13g, Eucalyptus globulus Labill 14g, Herba Ipomoeae Cairicae 25g, common mouse ear 18g, Colla Corii Asini 45g and 60% ethanol 3000ml.
Decubital ulcer medicine for external use and preparation method thereof is as follows: step 1., get propolis and Colla Corii Asini by above-mentioned weight ratio, under-18 degree environment, take out after freezing 6-8 hour, put into reducing mechanism and be ground into the granule that particle diameter is 1-3mm, pour in the 50%-65% alcoholic solution of 3000ml and soak; In immersion process, shake up 2-3 every day, each 3-5 minute; Soak and within least 7 days, get supernatant; 2. step is got other raw materials except propolis, Colla Corii Asini and ethanol by above-mentioned weight ratio and is put into reducing mechanism and be ground into the granule that particle diameter is 1-3mm, pouring step into 1. soaks in described supernatant and within 10-15 days, makes medicine liquid mixture, medicine liquid mixture is obtained to medicinal liquid after squeezing filter device squeezing, filtration, medicine liquid irrigation is packed in spray bottle and can be used.
The present invention not technology contents of detailed description is known technology.

Claims (5)

1. a decubital ulcer medicine for external use, it is characterized in that: it is made up of following raw material: Rhizoma Drynariae 20-35g, Radix seu Caulis Parthenocissi tricuspidatae 15-30g, Radix Sanguisorbae 100-120g, Cortex Phellodendri 50-70g, propolis 90-115g, Radix Kalopanacis 20-35g, Rhizoma Coptidis 15-25g, Radix Glycyrrhizae 15-20g, Radix Gentianae Macrophyllae 9-13g, Radix Aconiti Kusnezoffii Preparata 3-5g, Herba Sedi Linearis 15-30g, Radix Adenophorae (Radix Glehniae) 10-25g, Radix Scutellariae 30-50g, Folium et Ramulus Callicarpae nudiflorae 30-60g, Radix Syzygii Buxifolii 15-25g, Terra Flava Usta 15-20g, Herba stachydis kouyangensis 30-50g, Herba Asplenii Vaiainte Spleenwort 10-25g, Cortex Moutan 15-30g, Borneolum Syntheticum 3-6g, Hibisci Mutabilis root 25-45g, Phymatopsis griffithiana (Hook.) J. Sm. 10-20g, Fructus Ilicis Purpureae 9-15g, Eucalyptus globulus Labill 10-15g, Herba Ipomoeae Cairicae 15-30g, common mouse ear 15-25g, Colla Corii Asini 25-50g and 50%-65% ethanol 3000ml.
2. a kind of decubital ulcer medicine for external use according to claim 1, it is characterized in that: it is made up of following raw material: Rhizoma Drynariae 20g, Radix seu Caulis Parthenocissi tricuspidatae 20g, Radix Sanguisorbae 120g, Cortex Phellodendri 70g, propolis 100g, Radix Kalopanacis 30g, Rhizoma Coptidis 15g, Radix Glycyrrhizae 15g, Radix Gentianae Macrophyllae 9g, Radix Aconiti Kusnezoffii Preparata 3g, Herba Sedi Linearis 15g, Radix Adenophorae (Radix Glehniae) 10g, Radix Scutellariae 30g, Folium et Ramulus Callicarpae nudiflorae 50g, Radix Syzygii Buxifolii 15g, Terra Flava Usta 15g, Herba stachydis kouyangensis 30g, Herba Asplenii Vaiainte Spleenwort 10g, Cortex Moutan 20g, Borneolum Syntheticum 6g, Hibisci Mutabilis root 30g, Phymatopsis griffithiana (Hook.) J. Sm. 10g, Fructus Ilicis Purpureae 9g, Eucalyptus globulus Labill 15g, Herba Ipomoeae Cairicae 150g, common mouse ear 25g, Colla Corii Asini 25g and 50% ethanol 3000ml.
3. the preparation method of a kind of decubital ulcer medicine for external use according to claim 1, is characterized in that:
1. step, gets propolis and Colla Corii Asini by above-mentioned weight ratio, under-18 degree environment, takes out after freezing 6-8 hour, puts into reducing mechanism and is ground into the granule that particle diameter is 1-3mm, pours in the 50%-65% alcoholic solution of 3000ml and soaks; In immersion process, shake up 2-3 every day, each 3-5 minute; Soak and within least 7 days, get supernatant;
2. step is got other raw materials except propolis, Colla Corii Asini and ethanol by above-mentioned weight ratio and is put into reducing mechanism and be ground into the granule that particle diameter is 1-3mm, pouring step into 1. soaks in described supernatant and within 10-15 days, makes medicine liquid mixture, medicine liquid mixture is obtained to medicinal liquid after squeezing filter device squeezing, filtration, medicine liquid irrigation is packed in spray bottle and can be used.
4. the preparation method of a kind of decubital ulcer medicine for external use according to claim 3, is characterized in that: described reducing mechanism is the large-scale pulverizer of 30B.
5. the preparation method of a kind of decubital ulcer medicine for external use according to claim 3, is characterized in that: described squeezing filter device is the concentrated pressure filter of 800 molding box formulas.
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CN105031326A (en) * 2013-11-09 2015-11-11 邹建峰 Preparation method for medicine for treating alcoholic cardiomyopathy
CN103536806B (en) * 2013-11-09 2015-08-19 王墨茹 A kind of pharmaceutical composition for the treatment of alcoholic cardiomyopathy
CN104825897A (en) * 2013-11-09 2015-08-12 孙明慧 Preparation method of therapeutic medicament for alcoholic myocardiopathy
CN103720879B (en) * 2014-01-12 2015-09-02 唐公杰 A kind of external traditional Chinese medicinal application for the treatment of decubital ulcer
CN107998431B (en) * 2017-12-22 2020-06-26 中国科学院城市环境研究所 Aromatic plant incense with sweet wormwood as monarch and preparation process thereof

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