CN110917177B - Hyperplastic scar plaster and its making method - Google Patents

Hyperplastic scar plaster and its making method Download PDF

Info

Publication number
CN110917177B
CN110917177B CN201910141122.5A CN201910141122A CN110917177B CN 110917177 B CN110917177 B CN 110917177B CN 201910141122 A CN201910141122 A CN 201910141122A CN 110917177 B CN110917177 B CN 110917177B
Authority
CN
China
Prior art keywords
parts
scar
silica gel
gel layer
breathable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201910141122.5A
Other languages
Chinese (zh)
Other versions
CN110917177A (en
Inventor
祝蕾
朱坤福
朱志腾
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shandong Yu He Tang Pharmaceutical Co ltd
Original Assignee
Shandong Yu He Tang Pharmaceutical Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shandong Yu He Tang Pharmaceutical Co ltd filed Critical Shandong Yu He Tang Pharmaceutical Co ltd
Priority to CN201910141122.5A priority Critical patent/CN110917177B/en
Publication of CN110917177A publication Critical patent/CN110917177A/en
Application granted granted Critical
Publication of CN110917177B publication Critical patent/CN110917177B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/648Myriapods, e.g. centipedes or millipedes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486Millettia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Abstract

The invention relates to the field of scar patches, in particular to a hyperplastic scar patch and a manufacturing method thereof. The breathable net cloth is arranged on the scar plaster structure, so that the breathability of the scar plaster can be effectively ensured; the scar patch injects the existing auxiliary liquid medicine into the scar part through the breathable mesh cloth and the treatment liquid circulation hole, so that the treatment effect of the scar patch can be effectively improved; during treatment, repeated operation is performed for many times, so that extension of scars is effectively promoted, and the absorption capacity of cells to medicines is improved.

Description

Hyperplastic scar plaster and its making method
Technical Field
The invention relates to the field of scar patches, in particular to a hyperplastic scar patch and a manufacturing method thereof.
Background
Hypertrophic scars are often found at the depth of the injury and only in dermal wounds. The pathological tissue difference of the hyperplastic scar and the normal scar is only the thickening of collagen fibers at the deep part of the scar, and the hyperplastic scar is in irregular arrangement, or in a wave shape, or wound into a rope shape. Hypertrophic scars are most likely to occur after healing of the surface of a deeply burned wound. Reticular proliferative scars are also common at the suture positions around the skin pieces after the skin grafting of the III-degree burn wound. In addition, the most common is any scar of the incision after the incision is closed. The hyperplastic scar appears as a prominent surface, irregular appearance, uneven height, flush, congestion, solid and tough. It has burning pain and pruritus.
At present, when the scar is treated in an auxiliary way, the covering treatment is mainly carried out through a scar paste. The scar paste is used for healing scars (hypertrophic scars and keloids) left at any part of a body due to operations, traffic accidents, incised wounds or burns, can provide a physical barrier between the scars and the external environment to keep the scars moist and clean, thereby being beneficial to improving the overall condition of the scars, reducing the area and the color, playing a role in treatment, and also being matched with other scar treatment methods to enhance the treatment effect. The scar plaster plays an important role in the process of assisting in treating scars at present, so how to effectively improve the treatment effect of the scar plaster plays an important role in recovering scars.
Disclosure of Invention
The technical scheme adopted by the invention for solving one of the technical problems is as follows: the hyperplastic scar paste sequentially comprises a protective breathable layer, a silica gel layer and a dustproof film from inside to outside, wherein the protective breathable layer comprises a breathable mesh cloth with holes arranged on the upper side of the middle of the silica gel layer, two sides of the breathable mesh cloth are respectively connected with an elastic sticky cloth in a melting mode, the lengths of the two sides of the elastic sticky cloth are larger than that of the silica gel layer, the dustproof film is respectively bonded and attached to the bottom of the elastic sticky cloth and the bottom of the silica gel layer, and a plurality of treatment liquid flow through holes penetrating through the silica gel layer are formed in the silica gel layer from top to bottom.
Preferably, a protective film is covered and bonded on the upper part of the breathable mesh cloth, and two sides of the protective film are respectively bonded on the outer surfaces of the corresponding elastic sticky cloths.
Preferably, the total thickness of the protective breathable layer, the silicone gel layer, the dustproof film and the protective film is not more than 5mm.
Preferably, the silicone gel layer comprises the following components in parts by mass: 100-150 parts of self-adhesive silica gel, 10-25 parts of peppermint oil, 30-40 parts of pseudo-ginseng powder, 20-30 parts of folium artemisiae argyi, 40-60 parts of Chinese gall and 25-50 parts of caulis spatholobi.
Preferably, the silicone gel layer further comprises the following components in parts by mass: 15-30 parts of mutton tallow, 5-10 parts of centipede and 10-20 parts of vaseline.
The preparation method of the hypertrophic scar patch comprises the following steps:
s1: preparing raw materials;
preparing self-adhesive silica gel, oleum Menthae Dementholatum, folium Artemisiae Argyi, galla chinensis, caulis Spatholobi, scolopendra, notoginseng radix powder, adeps Caprae Seu Ovis, and vaseline as required; wherein the folium Artemisiae Argyi, galla chinensis, caulis Spatholobi, scolopendra, and Notoginseng radix powder are uniformly divided into powder before use, and adeps Caprae Seu Ovis is heated to melt and oil residue is filtered off.
S2: primary material mixing processing:
sequentially adding a first batch of raw materials (including self-adhesive silica gel, peppermint oil, folium artemisiae argyi, chinese gall, suberect spatholobus stem and centipede) meeting the quality part requirement into a mixing bin, repeatedly mixing and stirring, and simultaneously heating to obtain a primary product;
s3: secondary feeding:
keeping stirring the primary material obtained in the step S1, intermittently spraying the pseudo-ginseng powder into a mixing bin for multiple times, and uniformly mixing to obtain an intermediate material;
s3: consistency burdening:
adding a small amount of mutton tallow and vaseline into the intermediate material obtained in the step S2 successively, stirring and mixing, detecting the viscosity of the mixed material every 5 minutes, and stopping feeding after the viscosity reaches the standard;
s4: heating with slow fire for 1-2h to obtain the standby material;
s5: and (5) sucking the spare materials obtained in the step (S4) by the coating machine, and finally coating to form a silica gel layer.
The use method of the hypertrophic scar plaster comprises the following steps:
a1: cleaning scars;
a2: adhering the scar patch to the scar, and pressing to make the silica gel layer fully contact with the scar for 5-10min;
a3: pressing scar on scar with vibration massager for 3-5min, and softening connective tissue by mechanical oscillation of ultrasound to make medicine enter into cell to exert effect.
A4: uncovering the protective film and injecting the existing auxiliary liquid medicine into the scar part through the breathable net cloth and the treatment liquid circulation holes;
a5: repeating the operations A3-A4 for 3-5 times;
a6: after the scar plaster is used for 24 hours, the existing scar plaster is removed, the scar is aired, and the scar plaster is waited to be used next time.
The invention has the beneficial effects that:
1. the breathable net cloth is arranged on the scar plaster structure, so that the breathability of the scar plaster can be effectively ensured;
2. the folium artemisiae argyi, the gallnut, the caulis spatholobi and the centipede are added into the silica gel layer of the scar plaster, and the cooperation effect realizes that the collagen fiber of scar tissue generates larger ductility by the heat effect of the medicine, and then the hard connective tissue is softened by the mechanical oscillation of the ultrasonic, so that the medicine can fully enter the cells to play a role;
3. the existing auxiliary liquid medicine is injected into the scar part through the breathable mesh cloth and the treatment liquid circulation holes, so that the treatment effect of the scar patch can be effectively improved;
4. during treatment, repeated operation is performed for many times, so that extension of scars is effectively promoted, and the absorption capacity of cells to medicines is improved.
Drawings
In order to more clearly illustrate the detailed description of the invention or the technical solutions in the prior art, the drawings used in the detailed description or the prior art description will be briefly described below. Throughout the drawings, like elements or components are generally identified by like reference numerals. In the drawings, elements or components are not necessarily drawn to scale.
FIG. 1 is a schematic cross-sectional view of a layered structure of the present invention.
Fig. 2 is an enlarged schematic view of a portion a in fig. 1.
In the figure, 1, a protective breathable layer; 101. ventilating mesh cloth; 102. elastic adhesive cloth; 103. a therapeutic fluid flow aperture; 2. A layer of silicone gel; 3. a dust-proof film; 4. And (4) a protective film.
Detailed Description
Embodiments of the present invention will be described in detail below with reference to the accompanying drawings. The following examples are only for illustrating the technical solutions of the present invention more clearly, and therefore are only examples, and the protection scope of the present invention is not limited thereby.
As shown in fig. 1-2, the hypertrophic scar plaster sequentially comprises a protective breathable layer 1, a silicone gel layer 2 and a dustproof film 3 from inside to outside, wherein the protective breathable layer 1 comprises a breathable mesh cloth 101 with holes arranged on the upper side of the middle part of the silicone gel layer 2, two sides of the breathable mesh cloth 101 are respectively connected with an elastic sticky cloth 102 in a melting manner, the lengths of the two sides of the elastic sticky cloth 102 are both greater than the length of the silicone gel layer 2, the dustproof film 3 is respectively bonded and attached with the bottom of the elastic sticky cloth 102 and the bottom of the silicone gel layer 2, and a plurality of treatment liquid flow through holes 103 penetrating through the silicone gel layer 2 are arranged from top to bottom. The existing auxiliary liquid medicine is injected into the scar part through the breathable mesh cloth 101 and the treatment liquid through holes 103, so that the treatment effect of the scar patch can be effectively improved;
preferably, a protective film 4 is covered and bonded on the upper portion of the air permeable mesh cloth 101, and both sides of the protective film 4 are respectively bonded on the outer surfaces of the corresponding elastic adhesive cloths 102. When in use, the protective film 4 can prevent external dirt from entering into scars in a treatment state, and is more convenient and sanitary.
Preferably, the total thickness of the protective breathable layer 1, the silicone gel layer 2, the dustproof film 3 and the protective film 4 is not more than 5mm.
The silica gel layer 2 comprises the following components in parts by mass: 100-150 parts of self-adhesive silica gel, 10-25 parts of peppermint oil, 30-40 parts of pseudo-ginseng powder, 20-30 parts of folium artemisiae argyi, 40-60 parts of Chinese gall and 25-50 parts of caulis spatholobi.
The mint is pungent and cool in nature and mainly contains volatile oil, the main components of the oil are menthol, menthone, mentholate, limonene and the like, and the mint has the effects of dispelling wind and dissipating heat, and removing dirt and detoxifying. When the scar is left, the pain can be effectively relieved, the cooling and softening effects can restore the blood circulation to be normal, the skin cracking and itching can be relieved, the skin can be recovered to be healthy, and the itching feeling caused by the scar can be reduced.
The superstrong blood circulation promoting and blood stasis removing effects of the pseudo-ginseng are utilized to achieve the effects of promoting blood circulation to remove blood stasis and diminishing inflammation: the scar is softened and flattened, the effects of softening the scar and eliminating pain and itch are achieved, and the keloid is effectively treated.
The folium artemisiae argyi has the functions of diminishing inflammation and sterilizing, the probability of wound infection is greatly reduced by using the folium artemisiae argyi ash, and ugly scars cannot be formed without infection. The wound blots will disappear completely depending on the depth of the wound. Wounds that are too deep must leave marks, but not scars, the depth of which is related to whether the local blood supply is sufficient.
Galla chinensis has effects of relieving swelling and pain, and can be used for treating traumatic injury, and scar can be effectively treated by combining Notoginseng radix and folium Artemisiae Argyi.
The traditional Chinese medicine caulis spatholobi has the effects of clearing heat and removing toxicity, relaxing channels and activating collaterals, and promoting blood circulation and removing blood stasis, has a good effect on relaxing muscles and stimulating blood circulation, can effectively improve the fluidity of blood at a scar part after contacting the scar, improves the extensibility of cells at the scar part, and effectively improves the treatment effect by matching with later mechanical vibration treatment.
Preferably, the silicone gel layer 2 further comprises the following components in parts by mass: 15-30 parts of mutton tallow, 5-10 parts of centipede and 10-20 parts of vaseline.
The mutton tallow and the vaseline are added mainly for improving the moisture retention of the patch on scar wounds, and can be used for adjusting the viscosity of the whole silica gel and ensuring the spreadability of scars.
The method for manufacturing the hypertrophic scar patch comprises the following steps of:
s1: preparing raw materials;
preparing self-adhesive silica gel, oleum Menthae Dementholatum, folium Artemisiae Argyi, galla chinensis, caulis Spatholobi, scolopendra, notoginseng radix powder, adeps Caprae Seu Ovis, and vaseline as required; wherein the folium Artemisiae Argyi, galla chinensis, caulis Spatholobi, scolopendra, and Notoginseng radix powder are uniformly divided into powder before use, and adeps Caprae Seu Ovis is heated to melt and oil residue is filtered off.
S2: primary material mixing processing:
sequentially adding a first batch of raw materials (including self-adhesive silica gel, peppermint oil, folium artemisiae argyi, chinese gall, suberect spatholobus stem and centipede) meeting the quality part requirement into a mixing bin, repeatedly mixing and stirring, and simultaneously heating to obtain a primary product;
s3: secondary feeding:
keeping stirring the initial material obtained in the step S1, discontinuously spraying the pseudo-ginseng powder into a mixing bin for multiple times, and uniformly mixing to obtain an intermediate material; the mixing uniformity of the pseudo-ginseng powder is improved by adopting a spraying and multiple spraying mode.
S3: and (3) consistency burdening:
adding a small amount of mutton tallow and vaseline into the intermediate material obtained in the step S2, stirring and mixing, detecting the viscosity of the mixed material every 5 minutes, and stopping feeding after the viscosity reaches the standard;
s4: heating with slow fire for 1-2h to obtain the standby material;
s5: the coater sucks the spare material obtained in S4, and finally coats to form the silicone gel layer 2.
The application method of the hypertrophic scar patch comprises the following steps:
a1: cleaning scars;
a2: adhering the scar patch to the scar, and pressing to make the silicone gel layer 2 fully contact with the scar for 5-10min;
a3: pressing scar on scar with vibration massager for 3-5min, and softening connective tissue by mechanical oscillation of ultrasound to make medicine enter into cell to exert effect.
The folium artemisiae argyi, the gallnut, the caulis spatholobi and the centipede are added into the silica gel layer 2 of the scar plaster, and the cooperation effect realizes that the collagen fiber of scar tissue generates larger ductility by the heat effect of the medicine, and then the hard connective tissue is softened by the mechanical oscillation of the ultrasonic, so that the medicine can fully enter the cells to play a role; the existing auxiliary liquid medicine is injected into the scar part through the breathable mesh cloth 101 and the treatment liquid through holes 103, so that the treatment effect of the scar patch can be effectively improved; during treatment, repeated operation is performed for many times, so that extension of scars is effectively promoted, and the absorption capacity of cells to medicines is improved.
A4: uncovering the protective film 4 and injecting the existing auxiliary liquid medicine into the scar part through the breathable net cloth 101 and the therapeutic liquid through hole 103;
a5: repeating the operations A3-A4 for 3-5 times;
a6: after the scar paste is used for 24 hours, the existing scar paste is removed, the scar is dried in the air, and the next scar paste is waited to be used.
Example 1:
the silicone gel layer 2 comprises the following components in parts by mass: 100 parts of self-adhesive silica gel, 10 parts of peppermint oil, 30 parts of pseudo-ginseng powder, 20 parts of folium artemisiae argyi, 40 parts of Chinese gall and 25 parts of caulis spatholobi.
The silicone gel layer 2 further comprises the following components in parts by mass: 15 parts of mutton tallow, 5 parts of centipede and 10 parts of vaseline.
The method for manufacturing the hypertrophic scar patch comprises the following steps of:
s1: preparing raw materials;
preparing self-adhesive silica gel, oleum Menthae Dementholatum, folium Artemisiae Argyi, galla chinensis, caulis Spatholobi, scolopendra, notoginseng radix powder, adeps Caprae Seu Ovis, and vaseline as required; wherein the folium Artemisiae Argyi, galla chinensis, caulis Spatholobi, scolopendra, and Notoginseng radix powder are uniformly divided into powder before use, and the adeps Caprae Seu Ovis is heated to melt and oil residue is filtered off.
S2: primary material mixing processing:
sequentially adding a first batch of raw materials (including self-adhesive silica gel, peppermint oil, folium artemisiae argyi, chinese gall, suberect spatholobus stem and centipede) meeting the quality part requirement into a mixing bin, repeatedly mixing and stirring, and simultaneously heating to obtain a primary product;
s3: secondary feeding:
keeping stirring the primary material obtained in the step S1, intermittently spraying the pseudo-ginseng powder into a mixing bin for multiple times, and uniformly mixing to obtain an intermediate material;
s3: and (3) consistency burdening:
adding a small amount of mutton tallow and vaseline into the intermediate material obtained in the step S2, stirring and mixing, detecting the viscosity of the mixed material every 5 minutes, and stopping feeding after the viscosity reaches the standard;
s4: heating with slow fire for 1-2h to obtain the standby material;
s5: the coater sucks the spare material obtained in S4, and finally coats to form the silicone gel layer 2.
The application method of the hypertrophic scar patch comprises the following steps:
a1: cleaning scars;
a2: adhering the scar patch to the scar, and pressing to make the silicone gel layer 2 fully contact with the scar for 5-10min;
a3: pressing scar on scar with vibration massager for 3-5min, and softening connective tissue by mechanical oscillation of ultrasound to make medicine enter into cell to exert effect.
A4: uncovering the protective film 4 and injecting the existing auxiliary liquid medicine into the scar part through the breathable mesh cloth 101 and the treatment liquid through hole 103;
a5: repeating the operations A3-A4 for 3-5 times;
a6: after the scar paste is used for 24 hours, the existing scar paste is removed, the scar is dried in the air, and the next scar paste is waited to be used.
Example 2:
the silica gel layer 2 comprises the following components in parts by mass: 120 parts of self-adhesive silica gel, 14 parts of peppermint oil, 32 parts of pseudo-ginseng powder, 22 parts of folium artemisiae argyi, 45 parts of Chinese gall and 32 parts of caulis spatholobi.
The silica gel layer 2 further comprises the following components in parts by mass: 18 parts of mutton tallow, 6 parts of centipede and 12 parts of vaseline.
The method of producing the hypertrophic scar patch, the method of preparing the silicone gel layer 2, was the same as in example 1.
Example 3:
the silicone gel layer 2 comprises the following components in parts by mass: 130 parts of self-adhesive silica gel, 18 parts of peppermint oil, 35 parts of pseudo-ginseng powder, 25 parts of folium artemisiae argyi, 50 parts of Chinese gall and 40 parts of caulis spatholobi.
The silica gel layer 2 further comprises the following components in parts by mass: 22 parts of mutton tallow, 7 parts of centipede and 15 parts of vaseline.
The method of producing the hypertrophic scar patch, the method of preparing the silicone gel layer 2, was the same as in example 1.
Example 4:
the silica gel layer 2 comprises the following components in parts by mass: 140 parts of self-adhesive silica gel, 22 parts of peppermint oil, 37 parts of pseudo-ginseng powder, 27 parts of folium artemisiae argyi, 55 parts of Chinese gall and 43 parts of caulis spatholobi.
The silica gel layer 2 further comprises the following components in parts by mass: 27 parts of mutton tallow, 8 parts of centipede and 17 parts of vaseline.
The method of producing the hypertrophic scar patch, the method of preparing the silicone gel layer 2, was the same as in example 1.
Example 5:
the silica gel layer 2 comprises the following components in parts by mass: 150 parts of self-adhesive silica gel, 25 parts of peppermint oil, 40 parts of pseudo-ginseng powder, 30 parts of folium artemisiae argyi, 60 parts of Chinese gall and 50 parts of caulis spatholobi.
The silicone gel layer 2 further comprises the following components in parts by mass: 30 parts of mutton tallow, 10 parts of centipede and 20 parts of vaseline.
The method of producing the hypertrophic scar patch, the method of preparing the silicone gel layer 2, was the same as in example 1.
Comparative example 1: the common scar paste is adopted to adhere the scar.
After 1 month of continuous use of the patch for a plurality of patients with similar constitutions according to each of examples and comparative examples, it was found that the tendency of the scar to spread and flatten was significantly better in the patients who used the patch and the treatment method of this example than in the patients who used the conventional patch.
The breathable mesh cloth 101 is arranged on the scar plaster structure, so that the breathability of the scar plaster can be effectively ensured; the folium artemisiae argyi, the gallnut, the caulis spatholobi and the centipede are added into the silica gel layer 2 of the scar plaster, and the cooperation effect is realized that firstly, the collagen fiber of scar tissue generates larger ductility by the heat effect of the medicament, and then, the hard connective tissue is softened by the mechanical oscillation of the ultrasonic so that the medicament fully enters the cells to play a role; the existing auxiliary liquid medicine is injected into the scar part through the breathable mesh cloth 101 and the treatment liquid through holes 103, so that the treatment effect of the scar patch can be effectively improved; during treatment, repeated operation is performed for many times, so that extension of scars is effectively promoted, and the absorption capacity of cells to medicines is improved.
The above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; the modifications or the substitutions do not cause the essence of the corresponding technical solutions to depart from the scope of the technical solutions of the embodiments of the present invention, and the technical solutions are all covered in the scope of the claims and the specification of the present invention; it will be apparent to those skilled in the art that any alternative modifications or variations to the embodiments of the present invention may be made within the scope of the present invention.
The present invention is not described in detail, but is known to those skilled in the art.

Claims (1)

1. Hyperplastic scar subsides, its characterized in that: the protective breathable fabric comprises a protective breathable layer, a silica gel layer and a dustproof film from inside to outside in sequence, wherein the protective breathable layer comprises a breathable mesh fabric with holes arranged on the upper side of the middle part of the silica gel layer, two sides of the breathable mesh fabric are respectively connected with an elastic sticky cloth in a melting mode, the lengths of the two sides of the elastic sticky cloth are larger than that of the silica gel layer, the dustproof film is respectively bonded and attached to the bottom of the elastic sticky cloth and the bottom of the silica gel layer, and a plurality of treatment liquid flow through holes penetrating through the silica gel layer are formed in the silica gel layer from top to bottom;
a protective film is covered and bonded on the upper part of the breathable net cloth, and two sides of the protective film are respectively bonded on the outer surfaces of the corresponding elastic adhesive cloths;
the total thickness of the protective breathable layer, the silicone gel layer, the dustproof film and the protective film is not more than 5mm;
the silicon gel layer comprises the following components in parts by mass: 100-150 parts of self-adhesive silica gel, 10-25 parts of peppermint oil, 30-40 parts of pseudo-ginseng powder, 20-30 parts of folium artemisiae argyi, 40-60 parts of Chinese gall and 25-50 parts of caulis spatholobi;
the silica gel layer also comprises the following components in parts by mass: 15-30 parts of mutton tallow, 5-10 parts of centipede and 10-20 parts of vaseline;
the preparation method of the silica gel layer comprises the following steps:
s1: preparing raw materials;
preparing self-adhesive silica gel, oleum Menthae Dementholatum, folium Artemisiae Argyi, galla chinensis, caulis Spatholobi, scolopendra, notoginseng radix powder, adeps Caprae Seu Ovis, and vaseline as required; wherein the folium Artemisiae Argyi, galla chinensis, caulis Spatholobi, scolopendra, and Notoginseng radix powder are uniformly divided into powder before use, and adeps Caprae Seu Ovis is heated to melt and oil residue is filtered;
s2: primary material mixing processing:
sequentially adding a first batch of raw materials meeting the quality part requirement, wherein the raw materials comprise self-adhesive silica gel, peppermint oil, folium artemisiae argyi, chinese gall, caulis spatholobi and centipedes, repeatedly mixing and stirring, and simultaneously heating to obtain a primary product;
s3: secondary feeding:
stirring the primary material obtained in the step S1, intermittently spraying the pseudo-ginseng powder into a mixing bin for multiple times, and uniformly mixing to obtain an intermediate material;
s3: and (3) consistency burdening:
adding a small amount of mutton tallow and vaseline into the intermediate material obtained in the step S2, stirring and mixing, detecting the viscosity of the mixed material every 5 minutes, and stopping feeding after the viscosity reaches the standard;
s4: heating with slow fire for 1-2h to obtain a standby material;
s5: the coater sucks the spare material obtained in step S4, and finally coats to form a silicone gel layer.
CN201910141122.5A 2019-02-26 2019-02-26 Hyperplastic scar plaster and its making method Active CN110917177B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910141122.5A CN110917177B (en) 2019-02-26 2019-02-26 Hyperplastic scar plaster and its making method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910141122.5A CN110917177B (en) 2019-02-26 2019-02-26 Hyperplastic scar plaster and its making method

Publications (2)

Publication Number Publication Date
CN110917177A CN110917177A (en) 2020-03-27
CN110917177B true CN110917177B (en) 2023-01-24

Family

ID=69855665

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910141122.5A Active CN110917177B (en) 2019-02-26 2019-02-26 Hyperplastic scar plaster and its making method

Country Status (1)

Country Link
CN (1) CN110917177B (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4624665A (en) * 1984-10-01 1986-11-25 Biotek, Inc. Method of transdermal drug delivery
CN205885639U (en) * 2016-05-16 2017-01-18 常州华联保健敷料有限公司 Can mark woundplast of medicament
CN206761831U (en) * 2017-01-17 2017-12-19 东莞市瑞信医疗用品有限公司 A kind of multi-functional bandage
CN107510884A (en) * 2017-09-30 2017-12-26 河南汇博医疗股份有限公司 A kind of Silica hydrogel elasticity scar plaster and preparation method thereof
CN208389182U (en) * 2017-08-24 2019-01-18 河南汇博医疗股份有限公司 A kind of elasticity scar plaster
CN209464182U (en) * 2017-10-30 2019-10-08 河南省健琪医疗器械有限公司 A kind of sterile gauze block

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4624665A (en) * 1984-10-01 1986-11-25 Biotek, Inc. Method of transdermal drug delivery
CN205885639U (en) * 2016-05-16 2017-01-18 常州华联保健敷料有限公司 Can mark woundplast of medicament
CN206761831U (en) * 2017-01-17 2017-12-19 东莞市瑞信医疗用品有限公司 A kind of multi-functional bandage
CN208389182U (en) * 2017-08-24 2019-01-18 河南汇博医疗股份有限公司 A kind of elasticity scar plaster
CN107510884A (en) * 2017-09-30 2017-12-26 河南汇博医疗股份有限公司 A kind of Silica hydrogel elasticity scar plaster and preparation method thereof
CN209464182U (en) * 2017-10-30 2019-10-08 河南省健琪医疗器械有限公司 A kind of sterile gauze block

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
五倍子、蜈蚣对瘢痕疙瘩成纤维细胞增殖和胶原合成的影响;任丽虹等;《实用美容整形外科杂志》;20031230(第06期);全文 *

Also Published As

Publication number Publication date
CN110917177A (en) 2020-03-27

Similar Documents

Publication Publication Date Title
CN1055297A (en) A kind of autofrettage of skin-moistening burn and scald medicine
CN1723931A (en) Cure-all ointment for treating burns and scald
CN101007128A (en) Powder and salve for hyperplasia protrusion rehabilitation and its preparation method
CN106474444A (en) A kind of external application Chinese medicine medicated bag formula, medicated bag and its using method
KR20180110474A (en) An eye patch for eliminating black eye circles
CN110917177B (en) Hyperplastic scar plaster and its making method
CN103405571B (en) Externally applied medicament for treating herpes zoster and preparation method thereof
CN104173655A (en) Medicated wine for curing traumatic injury
CN103735962B (en) A kind of prickly-heat powder and preparation method thereof
KR102318809B1 (en) An Eye Patch for Eliminating Black Eye Circles
CN1293897C (en) Burn and scald treating powder
KR102293235B1 (en) An eye patch for eliminating black eye circles
CN100391507C (en) Method of preparing medicine for treating condyloma acuminatum
CN114209743A (en) Oyster ointment for external use for burns and scalds and preparation method thereof
CN107693714A (en) A kind of Chinese medicine composition for repairing face skin care and its preparation method and application
CN107693642A (en) A kind of set a broken bone drug paste
CN102078548A (en) Nano elemental Chinese medicinal far-infrared application agent for preventing and treating fungal infection of hand
CN101721659A (en) Plaster for treating rheumatism
CN1269499C (en) Medicine efficacious for burn and preparation method
CN106039153A (en) Tinea damp lotion prepared from snake and traditional Chinese medicinal medicine extracting solutions
CN105169123B (en) A kind of traditional Chinese medicine powder and preparation method thereof for treating children's extreme noxious heat varicella
CN112156151A (en) External spray for treating burns and scalds and preparation method thereof
CN105560846A (en) Plaster for treating burns and preparation method thereof
CN105395787A (en) Medicinal liquor
CN116712502A (en) External bone-knitting plaster and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant