CN110917077A - Natural plant bath foam - Google Patents

Natural plant bath foam Download PDF

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Publication number
CN110917077A
CN110917077A CN201811094187.0A CN201811094187A CN110917077A CN 110917077 A CN110917077 A CN 110917077A CN 201811094187 A CN201811094187 A CN 201811094187A CN 110917077 A CN110917077 A CN 110917077A
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percent
extract
oil
mint
liquid
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CN110917077B (en
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许旭东
朱霄伟
马国需
朱乃亮
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Triangle Mountain Beijing Biotechnology Co ltd
Xinyang Triangle Mountain Biotechnology Co ltd
Institute of Medicinal Plant Development of CAMS and PUMC
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Triangle Mountain Beijing Biotechnology Co ltd
Xinyang Triangle Mountain Biotechnology Co ltd
Institute of Medicinal Plant Development of CAMS and PUMC
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Priority to CN201811094187.0A priority Critical patent/CN110917077B/en
Priority to PCT/CN2019/099838 priority patent/WO2020057285A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/02Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/84Products or compounds obtained by lyophilisation, freeze-drying

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Pest Control & Pesticides (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

A natural plant body wash comprising: 1 to 1.5 percent of mint extract, 2.0 to 3.0 percent of grifola frondosa extract, 1.0 to 1.5 percent of atractylodes rhizome oil, 1.0 to 1.2 percent of cassia twig oil, 0.5 to 1.0 percent of cocamide DEA, 2.0 to 3.0 percent of TEA lauryl sodium sulfate, 1.0 to 2.0 percent of CP-920 pearly luster slurry, 0.5 to 0.8 percent of glycerol, 0.1 to 0.3 percent of essence and the balance of purified water. The natural plant bath foam can quickly remove mites and sterilize, has a good cleaning effect, and can clean, soften and moisten skin.

Description

Natural plant bath foam
Technical Field
The invention relates to natural plant bath foam.
Background
The bath foam is also called bath lotion, and the effective substance of the bath foam is a liquid body-cleaning skin-protecting bath product compounded by various surfactants. The Chinese ancient has the soaking medicated bath for curing diseases and strengthening the body, the history is long-flowing, a lot of precious historical materials are left for the modern health care and beauty industry, and the Chinese medicine bath product prepared by combining with the modern advanced extraction and preparation technology is more favored by consumers. In recent years, with the change of consumption concept and the development of cosmetic industry, the requirements of consumers for bath foam have changed, people pay more and more attention to the skin care effect, and firstly, the bath foam is required to have low irritation to the skin and mild effect, and the washing and the skin care are put on the same level.
Most of the existing bath foam only has a single cleaning function, the mite-removing and skin-moistening effects are not ideal, the existing bath foam has certain mite-killing effects, most of the existing bath foam are organic chemical synthesis bactericidal components, and the existing bath foam can cause certain damage to human bodies after long-term use.
Disclosure of Invention
The invention aims to provide natural plant bath foam capable of quickly removing mites and sterilizing.
According to a first aspect of the present invention, there is provided a bath foam comprising (by weight): 1 to 1.5 percent of mint extract, 2.0 to 3.0 percent of grifola frondosa extract, 1.0 to 1.5 percent of atractylodes rhizome oil, 1.0 to 1.2 percent of cassia twig oil, 0.5 to 1.0 percent of cocamide DEA, 2.0 to 3.0 percent of TEA lauryl sodium sulfate, 1.0 to 2.0 percent of CP-920 pearly luster slurry, 0.5 to 0.8 percent of glycerol, 0.1 to 0.3 percent of essence and the balance of purified water. Wherein DEA represents diethylamino, and TEA represents triethylamine.
According to a second aspect of the present invention, there is provided a method for producing the above-mentioned bath foam, comprising:
adding DEA, TEA sodium dodecyl sulfate, herba Menthae extract, flos Mori extract, CP-920 nacre slurry, glycerol and essence into purified water, stirring to dissolve completely;
and finally, adding the atractylodes rhizome oil and the cassia twig oil, stirring uniformly and filling.
According to the production method of the present invention, the atractylodes rhizome (volatile) oil and/or the cassia twig (volatile) oil can be prepared by steam distillation.
According to the production method of the present invention, the grifola frondosa extract is preferably obtained by the following manner to secure the stability of the extract:
pulverizing the grifola frondosa into medicinal powder, and then filling the medicinal powder into an extraction kettle;
will be derived from CO2CO flowing out of steel cylinder2Cooling the gas into liquid, and then inputting the liquid into a pressurizing pump for compression;
CO flowing from the pressure pump2Preheating by a preheater, and then entering an extraction kettle to reach a supercritical fluid state;
make CO2The supercritical fluid directly contacts with the medicinal powder for mass transfer;
CO flowing out of the extraction vessel2The supercritical fluid is decompressed and then sequentially enters a separation kettle I and a separation kettle II, wherein: keeping the temperature at 60 ℃ and the pressure at 6MPa in a separation kettle I; the temperature in the separation kettle II is kept at 55 ℃ and the pressure is 5 MPa; and
CO flowing out of the separation vessel II2And from CO2CO flowing out of steel cylinder2Converge to repeat the above steps.
According to the production method of the present invention, the mint extract is preferably obtained by: squeezing fresh folium Menthae physically, collecting fresh juice, centrifuging with high speed filter (4000 rpm/S), discarding precipitate to obtain herba Menthae solution, freezing the herba Menthae solution in-80 deg.C refrigerator until the liquid is completely solid, and freeze drying the solid in freeze dryer for 48 hr to obtain herba Menthae extract (powder).
The natural plant bath foam produced according to the invention can quickly remove mites and sterilize, has good cleaning effect, and can clean, soften and moisten skin.
In addition, the bath foam produced according to the present invention is excellent in performance, wherein the activity of the extract obtained after subjecting the sensitive grifola frondosa to the above-mentioned two-step supercritical separation is particularly stable.
Drawings
Fig. 1 is a schematic view of an extraction process of a grifola frondosa extract according to the present invention.
Detailed Description
The invention relates to a cassia twig volatile oil, which is extracted from dried twigs of cinnamon belonging to Lauraceae, and has remarkable antibacterial, sedative and analgesic effects.
The rhizoma atractylodis volatile oil and the cassia twig volatile oil can be prepared by adopting a steam distillation method: 1) and (3) rhizoma atractylodis oil: pulverizing rhizoma Atractylodis into dry powder, placing into a steam distillation extractor containing 10 times of water, controlling temperature at 100 deg.C (+ -5 deg.C), stopping extraction for about 6 hr when the liquid flowing down from the branch pipe of the extractor is colorless, removing lower part of distilled water with separating funnel to obtain oily crude extract, sealing, and storing in 4 deg.C refrigerator for use. 2) Cassia twig oil: pulverizing ramulus Cinnamomi into dry powder, placing into a steam distillation extractor containing 12 times of water, controlling temperature at 100 deg.C (+ -5 deg.C), stopping extraction for about 6 hr when the liquid flowing down from the branch pipe of the extractor is colorless, removing lower part of distilled water with separating funnel to obtain oily crude extract, sealing, and storing in 4 deg.C refrigerator for use.
Fig. 1 shows the extraction process of grifola frondosa extract of the present invention: pulverizing the grifola frondosa into medicinal powder, and then filling the medicinal powder into an extraction kettle; will be derived from CO2CO flowing out of steel cylinder2Cooling the gas into liquid, and then inputting the liquid into a pressurizing pump for compression; CO flowing from the pressure pump2Preheating by a preheater, and then entering an extraction kettle to reach a supercritical fluid state; make CO2The supercritical fluid directly contacts with the medicinal powder for mass transfer; CO flowing out of the extraction vessel2The supercritical fluid is decompressed and then sequentially enters a separation kettle I and a separation kettle II, wherein: keeping the temperature at 60 ℃ and the pressure at 6MPa in a separation kettle I; the temperature in the separation kettle II is kept at 55 ℃ and the pressure is 5 MPa; and CO flowing out of the separation vessel II2And from CO2CO flowing out of steel cylinder2Converge to repeat the above steps.
The mint extract of the present invention is obtained by: squeezing fresh folium Menthae physically, collecting fresh juice, centrifuging with high speed filter (4000 rpm/S), discarding precipitate to obtain herba Menthae solution, freezing the herba Menthae solution in-80 deg.C refrigerator until the liquid is completely solid, and freeze drying the solid in freeze dryer for 48 hr to obtain herba Menthae extract powder.
Other production materials are commercially available and will not be described in detail herein.
The production method of the bath foam comprises the following steps:
adding DEA, TEA sodium dodecyl sulfate, herba Menthae extract, flos Mori extract, CP-920 nacre slurry, glycerol and essence into purified water, stirring to dissolve completely;
and finally, adding the atractylodes rhizome oil and the cassia twig oil, stirring uniformly and filling.
The stirring is carried out mechanically at normal temperature for 15-20 minutes at a speed of about 200 rpm.
The following examples respectively show bath lotions of different compositions (parts by weight).
Example 1
1.0% of mint extract, 2.0% of grifola frondosa extract, 1.0% of rhizoma atractylodis volatile oil, 1.0% of cassia twig volatile oil, 0.5% of cocamide DEA, 2.0% of TEA lauryl sodium sulfate, 1.0% of CP-920 pearly luster slurry, 0.5% of glycerol, 0.1% of essence and the balance of purified water.
Example 2
1.0% of mint extract, 2.5% of grifola frondosa extract, 1.0% of rhizoma atractylodis volatile oil, 1.0% of cassia twig volatile oil, 0.5% of cocamide DEA, 2.0% of TEA lauryl sodium sulfate, 1.0% of CP-920 pearly luster slurry, 0.5% of glycerol, 0.1% of essence and the balance of purified water.
Example 3
1.0% of mint extract, 3.0% of grifola frondosa extract, 1.0% of rhizoma atractylodis volatile oil, 1.0% of cassia twig volatile oil, 0.5% of cocamide DEA, 2.0% of TEA lauryl sodium sulfate, 1.0% of CP-920 pearly luster slurry, 0.5% of glycerol, 0.1% of essence and the balance of purified water.
Example 4
1.5 percent of mint extract, 2.5 percent of grifola frondosa extract, 1.0 percent of rhizoma atractylodis volatile oil, 1.0 percent of cassia twig volatile oil, 0.5 percent of cocamide DEA, 2.0 percent of TEA lauryl sodium sulfate, 1.0 percent of CP-920 pearly luster slurry, 0.5 percent of glycerol, 0.1 percent of essence and the balance of purified water.
Example 5
1.5 percent of mint extract, 3.0 percent of grifola frondosa extract, 1.0 percent of rhizoma atractylodis volatile oil, 1.0 percent of cassia twig volatile oil, 0.5 percent of cocamide DEA, 2.0 percent of TEA lauryl sodium sulfate, 1.0 percent of CP-920 pearly luster slurry, 0.5 percent of glycerol, 0.1 percent of essence and the balance of purified water.
Test 1 mite removal test
60 volunteers are selected, male and female are not limited, and the age is 18-65 years. The test pieces were randomly divided into 5 groups, the bath liquids obtained in examples 1 to 5 were used in groups 1 to 5, respectively, and the bath liquid containing no mint extract or grifola frondosa extract was used as a control in group 6 (conventional amount, 1 to 3 times per week, follow-up evaluation after continuous use for 2 months, and the results are shown in table 1.
The evaluation standard is as follows: full effect: no acarid is detected in a conventional way, the skin is smooth, and no side effect is caused;
the method has the following advantages: a small amount of mites can be seen in the conventional detection, the skin is smooth, and no side effect is caused;
and (4) invalidation: a large amount of mites can be seen in the conventional detection, the skin is rough, and no side effect is caused.
TABLE 1 evaluation results of different baths
Figure BDA0001805140670000051
Figure BDA0001805140670000061
As can be seen from Table 1, the effective rates of the 1 st group and the 5 th group using the bath foam of the invention are all more than 90%, and are improved by more than 20% compared with the 6 th group used as a contrast, which proves that the natural bath foam has good mite-removing and cleaning effects, and can clean, soften and moisten skin.
Test 2 quantitative Sterilization test of suspension
(1) Three strains of staphylococcus aureus, escherichia coli and candida albicans are selected to respectively prepare the bacterial suspension for experiments according to the disinfection technical specification, and the concentration is 1 multiplied by 108cfu/ml to 5 multiplied by 108 cfu/ml.
(2) Taking a large sterile test tube for a disinfection test, firstly adding 0.5ml of test bacterial suspension, then adding 0.5ml of organic interfering substance, uniformly mixing, placing in a water bath at 20 +/-1 ℃ for 5min, sucking 4.0ml of sample of the natural plant bath foam prepared in each example by using a sterile pipette, injecting into the sample, rapidly mixing uniformly and immediately timing.
(3) When the test bacteria and the bath foam interact for each preset time, 0.5ml of the mixed liquid of the test bacteria and the bath foam is respectively sucked and added into 4.5ml of sterilized neutralizing agent, and the mixture is evenly mixed.
(4) Adding neutralizing agent into each tube of test bacteria and bath lotion, reacting for 10min, respectively sucking 1.0ml sample liquid, determining viable bacteria number by viable bacteria culture counting method, and inoculating 2 plates to each tube of sample liquid. If the number of colonies growing on the plate is large, serial 10-fold dilution can be performed, and viable bacteria culture counting can be performed.
(5) The bath foam was replaced by the diluent, and a parallel test was performed as a positive control.
(6) Culturing all test samples in an incubator at 37 ℃, and culturing the bacterial propagules for 48 hours to observe the final result; the bacterial spores were cultured for 72h to observe the final result.
(7) The test was repeated 3 times, and the viable bacteria concentration (cfu/ml) of each group was calculated and converted to a logarithmic value (N), and then the killing logarithmic value was calculated as follows:
the log Kill (KL) is the log of the average viable bacteria concentration of the control group (No) -log of the viable bacteria concentration of the test group (Nx) the results of the test are shown in table 1.
TABLE 2 results of the bactericidal test of the bath foam according to the different examples (action time <10min)
Figure BDA0001805140670000071
From the above, the natural plant essential oil bath foam has good cleaning effect, can clean, soften and moisten skin and kill and hide skin, has multiple effects, and is simple in product configuration and low in cost. The traditional Chinese medicine components in the formula have the effects of expelling wind-damp, relaxing muscles and bones and moistening skin, also have the effects of resisting bacteria, relieving skin keratinization and softening skin, and have remarkable mite removing effect.

Claims (5)

1. A body wash comprising: 1 to 1.5 percent of mint extract, 2.0 to 3.0 percent of grifola frondosa extract, 1.0 to 1.5 percent of atractylodes rhizome oil, 1.0 to 1.2 percent of cassia twig oil, 0.5 to 1.0 percent of cocamide DEA, 2.0 to 3.0 percent of TEA lauryl sodium sulfate, 1.0 to 2.0 percent of CP-920 pearly luster slurry, 0.5 to 0.8 percent of glycerol, 0.1 to 0.3 percent of essence and the balance of purified water.
2. The method of producing a body wash according to claim 1, comprising:
adding DEA, TEA sodium dodecyl sulfate, herba Menthae extract, flos Mori extract, CP-920 nacre slurry, glycerol and essence into purified water, stirring to dissolve completely;
and finally, adding the atractylodes rhizome oil and the cassia twig oil, stirring uniformly and filling.
3. The production method according to claim 2, wherein the extract of Grifola frondosa is obtained by:
pulverizing the grifola frondosa into medicinal powder, and then filling the medicinal powder into an extraction kettle;
will be derived from CO2CO flowing out of steel cylinder2Cooling the gas into liquid, and then inputting the liquid into a pressurizing pump for compression;
CO flowing from the pressure pump2Preheating by a preheater, and then entering an extraction kettle to reach a supercritical fluid state;
make CO2The supercritical fluid directly contacts with the medicinal powder for mass transfer;
CO flowing out of the extraction vessel2The supercritical fluid is decompressed and then sequentially enters a separation kettle I and a separation kettle II, wherein: keeping the temperature at 60 ℃ and the pressure at 6MPa in a separation kettle I; the temperature in the separation kettle II is kept at 55 ℃ and the pressure is 5 MPa; and
CO flowing out of the separation vessel II2And from CO2CO flowing out of steel cylinder2Converge to repeat the above steps.
4. The production method according to claim 2, wherein the mint extract is obtained by: physically squeezing fresh mint leaves, taking fresh juice, centrifuging by using a high-speed filter, removing precipitates to obtain mint liquid, freezing the mint liquid in a refrigerator at the temperature of-80 ℃ until the liquid is completely solid, and freeze-drying the solid in a freeze dryer for 48 hours to obtain the mint extract.
5. The production method according to claim 2, wherein the atractylodes rhizome oil and/or the cassia twig oil is obtained by steam distillation.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021022562A1 (en) * 2019-08-08 2021-02-11 中国医学科学院药用植物研究所 Pure natural compound essential oil having broad-spectrum bactericidal activity and preparation and application thereof

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CN104606106A (en) * 2015-02-13 2015-05-13 南通蛇类治疗研究所 Natural plant nano-emulsion bath lotion
CN106309199A (en) * 2015-06-18 2017-01-11 歌灵株式会社 Natural wipes for skin care and pest control and preparation method thereof
CN107519113A (en) * 2017-10-09 2017-12-29 广西三椿生物科技有限公司 A kind of moisturizing except mite shower cream and preparation method

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Publication number Priority date Publication date Assignee Title
US20100197544A1 (en) * 2009-02-03 2010-08-05 Edwin De La Cruz Rinseless body wash composition
WO2014023145A1 (en) * 2012-08-07 2014-02-13 Sun Yaru Mite killing bactericide and method for preparing same
CN104606106A (en) * 2015-02-13 2015-05-13 南通蛇类治疗研究所 Natural plant nano-emulsion bath lotion
CN106309199A (en) * 2015-06-18 2017-01-11 歌灵株式会社 Natural wipes for skin care and pest control and preparation method thereof
CN107519113A (en) * 2017-10-09 2017-12-29 广西三椿生物科技有限公司 A kind of moisturizing except mite shower cream and preparation method

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021022562A1 (en) * 2019-08-08 2021-02-11 中国医学科学院药用植物研究所 Pure natural compound essential oil having broad-spectrum bactericidal activity and preparation and application thereof

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