CN110882338A

CN110882338A - Preparation process of heat-clearing and detoxifying traditional Chinese medicine for livestock

Info

Publication number: CN110882338A
Application number: CN201911411230.6A
Authority: CN
Inventors: 李生龙; 颜秀梅; 刘文文; 王君; 王丽霞
Original assignee: ANHUI HUAAO BIOTECHNOLOGY Pty Ltd
Current assignee: ANHUI HUAAO BIOTECHNOLOGY Pty Ltd
Priority date: 2019-12-31
Filing date: 2019-12-31
Publication date: 2020-03-17

Abstract

The invention discloses a preparation process of a heat-clearing and detoxifying traditional Chinese medicine for animals, which comprises the following components in parts by weight: 3-6 parts of folium isatidis, 5-7 parts of radix isatidis, 5-7 parts of gypsum, 5-6 parts of rheum officinale, 4-5 parts of glauber salt, 4-6 parts of dried orange peel, 4-6 parts of astragalus membranaceus, 5-7 parts of scutellaria baicalensis, 3-5 parts of cinnamon, 3-6 parts of fried Chinese yam, 1-3 parts of codonopsis pilosula, 3-5 parts of desmodium and 3-5 parts of schizonepeta; by using the freeze dryer provided by the invention, the problems that the traditional vacuum heating drying method can inactivate the medicinal active substances with poor heat resistance and volatilize and lose the volatile medicinal active substances in the heating drying process can be solved.

Description

Preparation process of heat-clearing and detoxifying traditional Chinese medicine for livestock

Technical Field

The invention relates to the field of veterinary traditional Chinese medicines, and in particular relates to a preparation process of a veterinary traditional Chinese medicine for clearing away heat and toxic materials.

Background

Poultry are important economic animals, and poultry plague diseases uniformly restrict the development of poultry farming industry, and common diseases of poultry comprise: avian colibacillosis, chronic respiratory disease, avian influenza, avian infectious bursal disease, avian infectious bronchitis, avian infectious laryngotracheitis, etc. At present, poultry diseases are more and more complicated in morbidity, single diseases are few, the single diseases mostly appear in a mixed infection form, western medicines mostly directly act on a pathogen, and traditional Chinese medicines mostly have broad-spectrum antibacterial and antiviral effects, can recover the body function, and are better for treating mixed susceptibility diseases.

The existing drying method of veterinary traditional Chinese medicines mainly adopts the principle of vacuum heating and drying, the heating method adopts a high-temperature and low-pressure environment to dry the medicines, so that the medicine active substances with poor heat resistance are easy to lose activity, and the heating and drying process also easily volatilizes and loses volatile medicine effect substances, so that the medicine effect of the medicines is greatly weakened.

Disclosure of Invention

The invention aims to provide a preparation process of a heat-clearing and detoxifying traditional Chinese medicine for animals, and the technical problems to be solved by the invention are as follows:

1. the traditional Chinese medicine for livestock only contains components for clearing away heat and toxic materials, and although the poultry can treat diseases after taking the traditional Chinese medicine, the time for recovering the body function is longer;

2. in the existing traditional Chinese medicine preparation process, the drying of the traditional Chinese medicine is mainly based on the principle of vacuum heating and drying, the drying method easily leads the medicinal active substances with poor heat resistance to lose activity, and the heating and drying process also easily leads the volatile medicinal active substances to be volatilized and lost;

3. the existing freeze dryer has a complex structure, and the pre-cooling of the medicine needs to be carried out outside the cold hydrazine, so that the freeze-drying operation is complicated.

The purpose of the invention can be realized by the following technical scheme:

a preparation process of a veterinary traditional Chinese medicine for clearing heat and removing toxicity comprises the following steps:

the method comprises the following steps: adding cortex Cinnamomi, herba Schizonepetae, and distilled water into volatile oil extractor, and extracting by steam distillation for 4-6 hr to obtain volatile oil and residue;

step two: decocting the residues prepared in the step one, folium isatidis, radix isatidis, pericarpium citri reticulatae, radix scutellariae and fried Chinese yam with distilled water of which the mass is 10 times of the total mass of the medicaments, decocting for 2-3 hours, filtering to obtain a first filtrate, decocting the filter residues with distilled water of which the mass is 8 times of the total mass of the medicaments for 2-3 hours, filtering to obtain a second filtrate, and mixing the first filtrate and the second filtrate uniformly to obtain a water decoction liquid medicine;

step three: reflux-extracting radix Codonopsis, radix astragali, herba Lysimachiae Christinae, and radix et rhizoma Rhei with 5 times of ethanol, wherein the reflux process comprises refluxing with 75% ethanol for 2 times, each time for 1-2 hr, to obtain ethanol extractive solution;

step four: mixing the water decoction obtained in the second step with the ethanol extract obtained in the third step, concentrating the mixed solution into clear paste with the relative density of 1.3-1.4, adding gypsum, mirabilite and auxiliary materials, uniformly mixing, granulating by using a granulator, drying the obtained granules by using a freeze dryer, and spraying the volatile oil obtained in the first step to obtain the veterinary traditional Chinese medicine for clearing heat and removing toxicity.

The folium isatidis has the effects of clearing away heat and toxic materials, cooling blood and removing ecchymoses; the main treatment is as follows: can be used for treating fever with polydipsia; unconsciousness; macula; hematemesis; bleeding; jaundice; diarrhea and dysentery; erysipelas; pharyngitis; aphtha; mumps.

The radix isatidis has the following effects: clearing away heat and toxic materials, cooling blood, and relieving sore throat; the main treatment is as follows: epidemic febrile disease, fever, pharyngalgia, epidemic macula, mumps, throat rot, erysipelas, fever with swollen head, erysipelas, and carbuncle.

The gypsum is used for treating excess heat syndrome of qi system of warm diseases. It is often combined with Zhi mu in mutual reinforcement, such as Bai Hu Tang. For high fever with high heat and macula, it is often combined with blood-cooling and toxicity-removing herbs such as xi jiao and Xuan Shen, etc. to clear heat and remove macula, such as Hua ban Tang.

The rhubarb has the effects of purging heat and relaxing bowel, cooling blood and removing toxicity, and removing blood stasis and stimulating the menstrual flow, and is used for excess heat constipation, abdominal pain due to stagnation, diarrhea and dysentery and jaundice due to damp-heat.

The compound Chinese medicine has the effects of purging heat, relaxing bowels, softening hardness, dissipating stagnation, clearing away heat and toxic materials, clearing away lung-heat, relieving summer-heat, removing food retention and harmonizing stomach, and is mainly used for treating the following diseases: excessive heat, constipation, conjunctival congestion, swelling and pain, sore throat, aphtha, carbuncle, cellulitis, and toxic swelling.

The herba schizonepetae has the following effects: phlegm-eliminating, wind-dispelling and blood-cooling; it can be used for treating influenza, headache, cold, fever, sweating, and emesis.

Through using freeze dryer to dry veterinary traditional chinese medicine granule, can keep traditional chinese medicine extract's pharmacological activity, avoid the medicine in high temperature drying process, the rotten inactivation of pharmacodynamic component, freeze drying freezes into ice earlier with the moisture in the medicine granule simultaneously, makes moisture directly sublimate out from the medicine granule through vacuum condition, and the medicine granule keeps original granule dress, becomes the great granule of specific surface area, makes the absorption effect of medicine granule better.

The heat-clearing and detoxifying veterinary traditional Chinese medicine comprises the following components in parts by weight: 3-6 parts of folium isatidis, 5-7 parts of radix isatidis, 5-7 parts of gypsum, 5-6 parts of rheum officinale, 4-5 parts of glauber salt, 4-6 parts of dried orange peel, 4-6 parts of astragalus membranaceus, 5-7 parts of scutellaria baicalensis, 3-5 parts of cinnamon, 3-6 parts of fried Chinese yam, 1-3 parts of codonopsis pilosula, 3-5 parts of desmodium and 3-5 parts of schizonepeta.

Preferably, the auxiliary materials comprise 5-9 parts of cane sugar and 2-5 parts of dextrin by weight.

Preferably, the freeze dryer in the fourth step comprises a case shell, a compression refrigerator is fixedly connected to the bottom end face inside the case shell, a cold trap is mounted above the compression refrigerator, the top end face of the cold trap is fixedly connected to the inner wall of the top end face of the case shell, a spiral condenser pipe is mounted in the cold trap and is arranged close to the inner side wall of the cold trap, the spiral condenser pipe is communicated with the compression refrigerator, a fixing frame is fixedly connected to the bottom end face inside the cold trap, a groove is formed in the top end face of the fixing frame, a material tank is arranged above the fixing frame, the bottom end face of the material tank is located in the groove, the upper end of the material tank penetrates through the cold trap and the top end face of the case shell and extends to the upper side of the case shell, a first air suction opening and an air discharge valve are formed in the top end face of the material tank, the material tank can be cooled by the arrangement of, meanwhile, when the drug particles are freeze-dried, water can be desublimated on the spiral condenser pipe, so that water is locked, and the situation that the vacuum pump is damaged when the water enters the vacuum pump is avoided;

the lower end of the cold hydrazine is provided with a water outlet pipe and an air inlet, the upper end of the cold hydrazine is provided with a second extraction opening, the water outlet pipe, the air inlet and the second extraction opening are all positioned on the side wall of the cold hydrazine and are communicated with the inside of the cold hydrazine, the water outlet pipe is flush with the inner wall of the bottom end face of the cold hydrazine and extends to the outside of the chassis shell after penetrating through the chassis shell, the water outlet pipe is provided with a water outlet valve which is positioned on the water outlet pipe outside the chassis shell, the air inlet is positioned above the water outlet pipe and is communicated with the first extraction opening through a first vacuum pipe, the first vacuum pipe is provided with a vacuum valve, the second extraction opening is communicated with a drying tower through a second vacuum pipe, one end of the second vacuum pipe is communicated with the bottom end of the drying tower, the top end of the drying tower is communicated with a vacuum pipe of a vacuum pump, can be when the spiral condenser pipe defrosting, the convenience will melt the water discharge, avoids influencing the freeze drying effect because of ponding is too much, through setting up the outlet valve, can close the vacuum in guaranteeing the cold hydrazine when freeze drier uses, through setting up the drying tower, can absorb the aqueous vapor that gets into the second vacuum tube, prevents that moisture from getting into the vacuum pump, causes the damage to the vacuum pump.

Preferably, the material tank comprises a tank body and a tank cover, the tank cover is in threaded connection with the tank body, a limiting ring is fixedly connected to the side wall of the tank cover, a sealing ring is fixedly connected below the limiting ring, a supporting block is fixedly connected to the top end face inside the tank cover, a supporting frame is fixedly connected to the lower end of the supporting block, a filter plate is fixedly connected to the lower end of the supporting frame through a bolt, the side wall of the filter plate is attached to the inner side wall of the tank cover, a heat conducting wire is arranged in the side wall of the tank body, the limiting ring tightly presses the sealing ring to the top end face of the cold trap when the tank cover is screwed down with the tank body through the limiting ring and the sealing ring, the cold trap is ensured not to leak, the vacuum degree of the freeze dryer during operation is maintained, the filter plate is arranged to prevent medicine powder, the filter plate is fixed, and the filter plate is prevented from being broken due to the pressure difference of two sides when vacuum pumping is performed.

Preferably, the air discharge valve comprises a threaded opening, the threaded opening is fixedly connected to the top end face of the tank cover, an air inlet pipe is fixedly connected to the upper end of the threaded opening, a through hole is formed in the side wall of the air inlet pipe, a sealing gasket is fixedly connected to the top end face of the air inlet pipe, a threaded cover is connected to the threaded opening in a threaded manner, an air inlet hole is formed in the top end face of the threaded cover, the air discharge valve is arranged, when medicine particles are dried, air pressure in the material tank and the cold trap can be recovered to be normal through the air discharge valve, the threaded opening and the threaded cover are arranged, air can be more gradually sucked in the air discharge starting stage through the rotation of the.

Preferably, the corners of the bottom end face of the chassis shell are fixedly connected with universal wheels and parking rods, and the top end face of the material tank is also fixedly connected with a handle.

Preferably, the using method of the freeze dryer is as follows:

s1, opening a tank cover of the material tank, adding veterinary traditional Chinese medicine particles to be dried into the tank body, screwing the tank cover, enabling a sealing ring to be tightly attached to the top end face of the cold hydrazine, opening a compression refrigerator, reducing the temperature in the cold hydrazine to-DEG C, keeping-mi n, pre-freezing the veterinary traditional Chinese medicine particles, and freezing the veterinary traditional Chinese medicine particles into ice;

s2, opening a vacuum pump, checking that a vacuum valve is in an open state, checking that a water outlet valve is in a closed state, vacuumizing a cold hydrazine and a material tank, and continuously subliming ice in the veterinary Chinese medicinal granules under a critical vacuum freezing condition to achieve a drying effect;

s3, after drying, opening an air discharge valve to increase the air pressure in the cold hydrazine and material tank to atmospheric pressure, closing a vacuum pump and a compression refrigerator, electrifying a heat conducting wire in the tank body, heating the cold hydrazine and the tank body to-DEG C, screwing a handle and opening a tank cover to obtain the dried veterinary traditional Chinese medicine particles.

The invention has the beneficial effects that:

1. the poultry feed is prepared from folium isatidis, radix isatidis, gypsum, rheum officinale, exsiccated sodium sulfate, dried orange peel, astragalus membranaceus, scutellaria baicalensis, cinnamon, fried Chinese yam, codonopsis pilosula, desmodium and herba schizonepetae serving as main raw materials, wherein the folium isatidis, the radix isatidis, the gypsum, the rheum officinale, the exsiccated sodium sulfate and the herba schizonepetae have the effects of clearing away heat and toxic materials and treating poultry diseases, the astragalus membranaceus, the scutellaria baicalensis, the cinnamon, the fried Chinese yam, the codonopsis pilosula and the lysimachia christinae hance are beneficial to;

2. the veterinary traditional Chinese medicine granules are dried by using a freeze dryer, so that the medicinal activity of a traditional Chinese medicine extract can be maintained, the deterioration and inactivation of medicinal components of the medicine in a high-temperature drying process are avoided, meanwhile, the water in the medicine granules is firstly frozen into ice by freeze drying, the water is directly sublimated from the medicine granules under a vacuum condition, the medicine granules are kept in the original granule package and become granules with larger specific surface area, and the absorption effect of the medicine granules is better;

3. the material tank can be cooled by arranging the cold hydrazine, so that the medicine particles can be conveniently pre-frozen, the heat exchange area in the cold hydrazine is maximized by arranging the spiral condensing tube, and meanwhile, when the medicine particles are freeze-dried, moisture can be desublimated on the spiral condensing tube, so that the moisture is favorably locked, and the moisture is prevented from entering the vacuum pump to damage the vacuum pump; the water outlet pipe is arranged, so that melted water can be conveniently discharged when the spiral condensation pipe is defrosted, the freeze drying effect is prevented from being influenced by excessive accumulated water, the water outlet valve is arranged, the freeze dryer can be closed when in use to ensure the vacuum degree in the cold trap, and the drying tower is arranged to absorb water vapor entering the second vacuum pipe and prevent the water from entering the vacuum pump and damaging the vacuum pump; by arranging the limiting ring and the sealing ring, when the tank cover is screwed with the tank body, the limiting ring presses the sealing ring on the top end face of the cold trap to ensure that the cold trap is airtight, the vacuum degree of the freeze dryer during working is maintained, and by arranging the filter plate, the medicine powder generated after drying is prevented from being sprayed into the first air inlet and the first vacuum pipe during air discharge to cause pipeline blockage and influence the use of the machine; through setting up the air relief valve, accessible air relief valve resumes normally with the atmospheric pressure in material jar and the cold hydrazine when medicine granule is dry when finishing, and through setting up screw thread mouth and screw thread lid, rotatory screw thread lid makes the beginning stage of unloading admit air more milder, prevents that the air from hurry inhaling in the material jar, causes the machine to damage.

Drawings

In order to facilitate understanding for those skilled in the art, the present invention will be further described with reference to the accompanying drawings.

Fig. 1 is a schematic view of the overall structure of a freeze dryer;

FIG. 2 is a schematic view of the structure of a material tank in a freeze dryer;

FIG. 3 is a schematic view of a base mechanism in the freeze dryer;

FIG. 4 is a schematic view of the filter plate in the present freeze dryer;

FIG. 5 is a top view of the filter plate of the freeze dryer;

FIG. 6 is a schematic view of the structure of the air release valve in the freeze dryer;

in the figure: 1. a chassis housing; 2. a compression refrigerator; 3. cooling hydrazine; 4. a spiral condenser tube; 5. a fixed mount; 6. a groove; 7. a material tank; 8. a first air extraction opening; 9. an air relief valve; 10. a water outlet pipe; 11. an air inlet; 12. a second air extraction opening; 13. a water outlet valve; 14. a first vacuum tube; 15. a vacuum valve; 16. a second vacuum tube; 17. a drying tower; 18. a vacuum pump; 19. calcium chloride particles; 20. a tank body; 21. a can lid; 22. a limiting ring; 23. a seal ring; 24. a support block; 25. a support frame; 26. a filter plate; 27. heat conducting wires; 28. a threaded opening; 29. an air inlet pipe; 30. a through hole; 31. a gasket; 32. a threaded cap; 33. an air inlet; 34. a universal wheel; 35. a parking lever; 36. a handle.

Detailed Description

The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Please refer to FIGS. 1-6

step two: decocting the residues prepared in the step one, folium isatidis, radix isatidis, pericarpium citri reticulatae, radix scutellariae and fried Chinese yam with distilled water of which the mass is 10 times of the total mass of the medicaments, decocting for 2 hours, filtering to obtain a first filtrate, decocting the residues with distilled water of which the mass is 8 times of the total mass of the medicaments for 2 hours, filtering to obtain a second filtrate, and mixing the first filtrate and the second filtrate uniformly to obtain a water decoction liquid;

step three: reflux-extracting radix Codonopsis, radix astragali, herba Lysimachiae Christinae, and radix et rhizoma Rhei with 5 times of ethanol, wherein the reflux process comprises refluxing with 75% ethanol for 2 times, each time for 2 hr, to obtain ethanol extractive solution;

The veterinary traditional Chinese medicine for clearing away heat and toxic materials comprises the following components in parts by weight: 5 parts of folium isatidis, 6 parts of radix isatidis, 6 parts of gypsum, 6 parts of rheum officinale, 5 parts of glauber salt, 5 parts of pericarpium citri reticulatae, 5 parts of astragalus membranaceus, 6 parts of scutellaria baicalensis, 4 parts of cinnamon, 4 parts of fried Chinese yam, 3 parts of codonopsis pilosula, 5 parts of lysimachia christinae hance and 5 parts of schizonepeta.

The auxiliary materials comprise 6 parts of cane sugar and 2 parts of dextrin by mass.

The freeze dryer comprises a case shell 1, a compression refrigerator 2 is fixedly connected with the inner bottom end surface of the case shell 1, a cold trap 3 is arranged above the compression refrigerator 2, the top end surface of the cold trap 3 is fixedly connected to the inner wall of the top end surface of the case shell 1, a spiral condensing pipe 4 is arranged in the cold trap 3, the spiral condensing pipe 4 is arranged close to the inner side wall of the cold trap 3, the spiral condensing pipe 4 is communicated with the compression refrigerator 2, a fixing frame 5 is fixedly connected with the inner bottom end surface of the cold trap 3, a groove 6 is arranged on the top end surface of the fixing frame 5, a material tank 7 is arranged above the fixing frame 5, the bottom end surface of the material tank 7 is positioned in the groove 6, the upper end of the material tank 7 penetrates through the cold trap 3 and the top end surface of the case shell 1 and extends to the upper side of the case shell 1, a first air suction opening 8 and an air discharge, the medicine particles are conveniently pre-frozen, the heat exchange area in the cold trap 3 is maximized by arranging the spiral condensation pipe 4, and meanwhile, when the medicine particles are freeze-dried, moisture can be desublimated on the spiral condensation pipe 4, so that the moisture is favorably locked, and the moisture is prevented from entering the vacuum pump 18 and damaging the vacuum pump 18;

the lower end of the cold trap 3 is provided with a water outlet pipe 10 and a gas inlet 11, the upper end is provided with a second pumping port 12, the water outlet pipe 10, the gas inlet 11 and the second pumping port 12 are all positioned on the side wall of the cold trap 3 and are communicated with the inside of the cold trap 3, the water outlet pipe 10 is flush with the inner wall of the bottom end face of the cold trap 3 and extends to the outside of the chassis shell 1 after penetrating through the chassis shell 1, the water outlet pipe 10 is provided with a water outlet valve 13, the water outlet valve 13 is positioned on the water outlet pipe 10 outside the chassis shell 1, the gas inlet 11 is positioned above the water outlet pipe 10, the gas inlet 11 is communicated with the first pumping port 8 through a first vacuum pipe 14, the first vacuum pipe 14 is provided with a vacuum valve 15, the second pumping port 12 is communicated with a drying tower 17 through a second vacuum pipe 16, one end of the second vacuum pipe 16 is communicated with the bottom end of the drying, vacuum pump 18 and the equal fixed connection of drying tower 17 are on the inside bottom face of chassis exterior 1, through setting up outlet pipe 10, can be when the frost is changed to spiral condenser pipe 4, and the convenience is discharged the water that will melt, avoids influencing the freeze-drying effect because of ponding is too much, through setting up outlet valve 13, can close when freeze drier uses and guarantee the vacuum in the hydrazine hydrate 3.

The material tank 7 comprises a tank body 20 and a tank cover 21, the tank cover 21 is in threaded connection with the tank body 20, a limit ring 22 is fixedly connected to the side wall of the tank cover 21, a seal ring 23 is fixedly connected below the limit ring 22, a support block 24 is fixedly connected to the top end face inside the tank cover 21, a support frame 25 is fixedly connected to the lower end of the support block 24, a filter plate 26 is fixedly connected to the lower end of the support frame 25 through a bolt, the side wall of the filter plate 26 is attached to the inner side wall of the tank cover 21, a heat conducting wire 27 is arranged inside the side wall of the tank body 20, through the arrangement of the limit ring 22 and the seal ring 23, when the tank cover 21 is screwed with the tank body 20, the seal ring 23 is tightly pressed on the top end face of the cold trap 3 by the limit ring 22, the cold trap 3 is ensured to be airtight, the vacuum degree of the, influence the machine and use, through setting up supporting shoe 24 and support frame 25, fix filter 26, when preventing the evacuation, filter 26 causes the fracture because of the both sides atmospheric pressure difference.

Air relief valve 9 includes screw thread mouth 28, screw thread mouth 28 fixed connection is on cover 21 top terminal surface, screw thread mouth 28 upper end fixedly connected with intake pipe 29, through-hole 30 has been seted up on the intake pipe 29 lateral wall, intake pipe 29 top terminal surface fixedly connected with seals up the pad 31, screw thread connection has screw thread lid 32 on the screw thread mouth 28, screw thread lid 32 top terminal surface has seted up inlet port 33, through setting up air relief valve 9, accessible air relief valve 9 resumes normal with the atmospheric pressure in material jar 7 and the cold hydrazine 3 when the dry end of medicine granule, through setting up screw thread mouth 28 and screw thread lid 32, rotatory screw thread lid 32 makes the stage of beginning to unload gas intake more mild, prevent in the violent inspiration material jar 7 of air, cause the machine to damage.

The corners of the bottom end face of the case shell 1 are fixedly connected with universal wheels 34 and parking rods 35, and the top end face of the material tank 7 is also fixedly connected with a handle 36.

The using method of the freeze dryer comprises the following steps:

s1, opening a tank cover 21 of the material tank 7, adding veterinary traditional Chinese medicine particles to be dried into a tank body 20, screwing the tank cover 21, enabling a limiting ring 22 to tightly press a sealing ring 23 on the top end surface of the cold hydrazine 3, opening the compression refrigerator 2, reducing the temperature in the cold hydrazine 3 to-40 ℃, keeping the temperature at 10 min, pre-freezing the veterinary traditional Chinese medicine particles, and freezing the veterinary traditional Chinese medicine particles into ice;

s2, opening the vacuum pump 18, checking that the vacuum valve 15 is in an open state and the water outlet valve 13 is in a closed state, vacuumizing the cold hydrazine 3 and the material tank 7, and continuously subliming ice in the veterinary traditional Chinese medicine particles under a vacuum freezing condition to achieve a drying effect;

s3, after drying, opening the gas discharge valve 9 to increase the pressure of the cold hydrazine 3 and the material tank 7 to atmospheric pressure, closing the vacuum pump 18 and the compression refrigerator 2, electrifying the heat conducting wire 27 in the tank body 20, heating the cold hydrazine 3 and the tank body 20 to room temperature, screwing the handle 36 and opening the tank cover 21 to obtain dried veterinary traditional Chinese medicine particles, and opening the water outlet valve 13 to discharge the water melted in the cold hydrazine 3.

The preferred embodiments of the invention disclosed above are intended to be illustrative only. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise forms disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best utilize the invention. The invention is limited only by the claims and their full scope and equivalents.

Claims

1. A preparation process of a veterinary traditional Chinese medicine for clearing heat and removing toxicity is characterized by comprising the following steps:

2. The preparation process of the heat-clearing and detoxifying traditional Chinese medicine for veterinary use according to claim 1, wherein the heat-clearing and detoxifying traditional Chinese medicine for veterinary use comprises the following components in parts by weight: 3-6 parts of folium isatidis, 5-7 parts of radix isatidis, 5-7 parts of gypsum, 5-6 parts of rheum officinale, 4-5 parts of glauber salt, 4-6 parts of dried orange peel, 4-6 parts of astragalus membranaceus, 5-7 parts of scutellaria baicalensis, 3-5 parts of cinnamon, 3-6 parts of fried Chinese yam, 1-3 parts of codonopsis pilosula, 3-5 parts of desmodium and 3-5 parts of schizonepeta.

3. The preparation process of the heat-clearing and detoxifying veterinary traditional Chinese medicine as claimed in claim 1, wherein the auxiliary material is a mixture of 5-9 parts by weight of sucrose and 2-5 parts by weight of dextrin.

4. The preparation process of the heat-clearing and detoxifying traditional Chinese medicine for veterinary use according to claim 1, wherein the using method of the freeze dryer is as follows:

s1, adding the veterinary traditional Chinese medicine particles to be dried into a material tank (7), opening a compression refrigerator (2), reducing the temperature in the cold hydrazine (3) to-40 ℃, keeping the temperature for 5-15min, and pre-freezing the veterinary traditional Chinese medicine particles;

s2, opening a vacuum pump (18), vacuumizing the cold hydrazine (3) and the material tank (7), and drying the veterinary traditional Chinese medicine particles;

s3, after drying, opening the air discharge valve (9), closing the vacuum pump (18) and the compression refrigerator (2), electrifying the heat conducting wires (27) in the tank body (20), heating the cold hydrazine (3) and the tank body (20) to 10-20 ℃, and opening the tank cover (21) to obtain the dried veterinary traditional Chinese medicine particles.

5. The preparation process of the heat-clearing and detoxifying traditional Chinese medicine for veterinary use according to claim 4, wherein the freeze dryer comprises a chassis housing (1), a compression refrigerator (2) is fixedly connected to the bottom end surface inside the chassis housing (1), a cold trap (3) is installed above the compression refrigerator (2), the top end surface of the cold trap (3) is fixedly connected to the inner wall of the top end surface of the chassis housing (1), a spiral condenser tube (4) is installed inside the cold trap (3), the spiral condenser tube (4) is arranged close to the inner wall of the cold trap (3), the spiral condenser tube (4) is communicated with the compression refrigerator (2), the bottom end surface inside the cold trap (3) is fixedly connected with a fixing frame (5), a groove (6) is formed in the top end surface of the fixing frame (5), a material tank (7) is arranged above the fixing frame (5), and the bottom end surface of the material tank (7) is located in, the upper end of the material tank (7) penetrates through the cold trap (3) and the top end face of the case shell (1) and extends to the upper part of the case shell (1), and a first air suction opening (8) and an air discharge valve (9) are arranged on the top end face of the material tank (7);

the lower end of the cold trap (3) is provided with a water outlet pipe (10) and an air inlet (11), the upper end of the cold trap is provided with a second air extraction opening (12), the water outlet pipe (10), the air inlet (11) and the second air extraction opening (12) are all positioned on the side wall of the cold trap (3) and are communicated with the interior of the cold trap (3), the water outlet pipe (10) is flush with the inner wall of the bottom end face of the cold trap (3) and penetrates through the case shell (1) to extend to the exterior of the case shell (1), the water outlet pipe (10) is provided with a water outlet valve (13), the water outlet valve (13) is positioned on the water outlet pipe (10) outside the case shell (1), the air inlet (11) is positioned above the water outlet pipe (10), the air inlet (11) is communicated with the first air extraction opening (8) through a first vacuum pipe (14), the first vacuum pipe (14) is provided with a vacuum valve (15), the second, one end of the second vacuum tube (16) is communicated with the bottom end of the drying tower (17), the top end of the drying tower (17) is communicated with the vacuumizing tube of the vacuum pump (18) through a pipeline, calcium chloride particles (19) are filled in the drying tower (17), and the vacuum pump (18) and the drying tower (17) are fixedly connected to the bottom end face in the case shell (1).

6. The preparation process of the heat-clearing and detoxifying traditional Chinese medicine for livestock according to claim 5, characterized in that the material tank (7) comprises a tank body (20) and a tank cover (21), the tank cover (21) is in threaded connection with the tank body (20), a limit ring (22) is fixedly connected to the side wall of the tank cover (21), a seal ring (23) is fixedly connected to the lower portion of the limit ring (22), a support block (24) is fixedly connected to the top end face inside the tank cover (21), a support frame (25) is fixedly connected to the lower end of the support block (24), a filter plate (26) is fixedly connected to the lower end of the support frame (25) through a bolt, the side wall of the filter plate (26) is attached to the inner side wall of the tank cover.

7. The preparation process of the heat-clearing and detoxifying traditional Chinese medicine for veterinary use as claimed in claim 5, wherein the air relief valve (9) comprises a threaded port (28), the threaded port (28) is fixedly connected to the top end face of the tank cover (21), the upper end of the threaded port (28) is fixedly connected with an air inlet pipe (29), the side wall of the air inlet pipe (29) is provided with a through hole (30), the top end face of the air inlet pipe (29) is fixedly connected with a sealing gasket (31), the threaded port (28) is in threaded connection with a threaded cover (32), and the top end face of the threaded cover (32) is provided with an air inlet hole (33.

8. The preparation process of the heat-clearing and detoxifying traditional Chinese medicine for veterinary use as claimed in claim 5, wherein the corners of the bottom end surface of the chassis housing (1) are fixedly connected with universal wheels (34) and parking rods (35), and the top end surface of the material tank (7) is also fixedly connected with a handle (36).