CN110876695A - Probiotic dandruff-removing shampoo - Google Patents

Probiotic dandruff-removing shampoo Download PDF

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CN110876695A
CN110876695A CN201911146786.7A CN201911146786A CN110876695A CN 110876695 A CN110876695 A CN 110876695A CN 201911146786 A CN201911146786 A CN 201911146786A CN 110876695 A CN110876695 A CN 110876695A
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probiotic
sodium
dandruff
shampoo
extract
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殷传江
杜养标
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Guangzhou Rui Yu Chemical Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9755Gymnosperms [Coniferophyta]
    • A61K8/9761Cupressaceae [Cypress family], e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/006Antidandruff preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair

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Abstract

The invention discloses probiotic dandruff-removing shampoo, which comprises inactivated lactobacillus paracasei, maltotetraose and soybean oil. The inactivated lactobacillus paracasei is added into the hair washing milk, and is used together with the soybean oil and the maltotetraose, so that the hair washing milk is beneficial to restoring the microecological balance of scalp flora and radically solves the problem of dandruff.

Description

Probiotic dandruff-removing shampoo
Technical Field
The invention relates to a shampoo, in particular to a probiotic dandruff-removing shampoo.
Background
The root cause of dandruff production, scalp ecological balance, is disrupted.
Dandruff results from the breakdown of the ecological balance of the scalp. In fact, a healthy scalp ecosystem is maintained by three major balances: oil, flora and metabolic balance. When the secretion of oil and fat of scalp is unbalanced, the oil of scalp is greasy; when the scalp flora is unbalanced in environment and a large amount of harmful bacteria are bred, the phenomenon of itching can occur; the stratum corneum of the scalp is metabolized too quickly and falls off to form dandruff.
The scalp is the most important command control center of human body, namely the natural barrier of the head, the fragility and the sensitivity of the scalp are second to the eyelid, and the scalp can be pulled to move the whole body. Scalp problems cannot be looked at, health management is required, and only comprehensive, systematic and scientific conditioning and maintenance are carried out on the scalp, so that the scalp problems such as the scalp oil can be fundamentally eliminated, and the healthy normality of the scalp is kept.
Specifically, scalp health management mainly includes three parts: firstly, scalp nursing consciousness is improved, good work and rest habits are developed secondly, and daily scalp nursing is well done thirdly; thus, prevention and symptomatic solution of scalp health problems can be achieved.
The shampoo has effects of cleaning hair and scalp, and is used for keeping hair and scalp clean. The existing shampoo products are generally divided into common cleaning type shampoo and special functional type shampoo according to functional classification; the common cleaning shampoo has only the efficacy of cleaning hair and scalp, but has no specific health care function; the shampoo with specific functions has the effects of treating dandruff and head itch, sterilizing, controlling oil and the like, but the shampoo with specific functions has the effects because chemical additives such as medicines, hormones and the like are added, and is not suitable for common people to use for a long time.
Disclosure of Invention
The invention aims to overcome the defects in the prior art and provide the probiotic dandruff-removing shampoo.
In order to achieve the purpose, the invention adopts the technical scheme that: a probiotic anti-dandruff shampoo comprising inactivated Lactobacillus paracasei, maltotetraose, and soybean oil.
The most abundant bacterial species on the scalp are lactobacilli and staphylococci, which exhibit a state of mutual inhibition with each other, while affecting the severity of dandruff. In the presence of dandruff, the number of lactobacilli in the nearby scalp decreases and the number of staphylococci increases compared to normal scalp. According to the invention, the inactivated lactobacillus paracasei is added into the shampoo, the lactobacillus paracasei is subjected to heat-killing inactivation, the addition of the inactivated lactobacillus paracasei into the shampoo can adjust the bacterial balance on the scalp, and particularly, the lactobacillus is enhanced while the staphylococcus is inhibited, so that the dandruff severity can be reduced. The maltotetraose is an itching-relieving and moisture-keeping component derived from plants. Can be used as antipruritic for scalp and skin, and humectant, and can be used in washing and washing-free products. Dry, sensitive skin, itchy nerve (C-fibers) can stretch, making the skin sensitive. The itch is easy to occur, and the maltotetraose has a good shielding effect on itch nerves, so that the sensitivity of the skin is reduced. The soybean oil can promote the growth of fibroblasts, and has the functions of activating skin and resisting aging; meanwhile, the skin moisture can be kept, and the moisturizing effect is achieved.
The maltotetraose and soybean oil can maintain the moisture content on the scalp, and the high moisture content on the scalp can provide a more suitable environment for the growth of lactobacillus, thereby reducing dandruff. Therefore, the maltultraose and the soybean oil are matched to inactivate the lactobacillus paracasei, which can help to restore the microecological balance of scalp flora and radically solve the dandruff problem.
Preferably, the shampoo comprises the following components in percentage by weight: 0.5-2% of inactivated lactobacillus paracasei, 0.5-2% of maltotetraose and 6-10% of soybean oil. The anti-dandruff effect of the components is better at the addition amount. More preferably, the hair washing cream comprises the following components in percentage by weight: 1% of inactivated lactobacillus paracasei, 1% of maltotetraose and 8% of soybean oil.
Preferably, the shampoo further comprises 0.5-2% of camellia extract and 0.4-0.6% of a mixture of magnolia rugosa bark extract, tea extract, pomelo fruit extract and thujoram twig extract. The extract has antibacterial, antiinflammatory and antioxidant effects, and can be used for improving dandruff removing effect of shampoo. In the mixture of butanediol, magnolia winkle bark extract, tea extract, pomelo fruit extract and Thujopsis dolabrata branch extract, the magnolia winkle bark extract, the tea extract, the pomelo fruit extract and the Thujopsis dolabrata branch extract are respectively in parts by weight: 4.5-5.5 parts of magnolia winkle bark extract, 2-3 parts of tea extract, 1-2 parts of pomelo fruit extract and 0.5-1.5 parts of Thujopsis dolabrata branch extract.
Preferably, the hair wash further comprises at least one of sodium levolactate, dihydroxypropyl arginine HCl, saccharide isomers, and sodium PCA.
Dihydroxypropyl arginine HCl is a novel low-molecular moisturizing active ingredient obtained by fusing widely used glycerin and natural amino acid, can greatly improve the adsorption effect of a moisturizing agent, improves the problem of water loss of skin and hair, and has strong adsorption feeling in a washing-off formula. PCA Na is one of the important components of the natural human body moisturizing factor and is the main component in the stratum corneum of the skin; the hygroscopicity is high, and under the same environmental conditions, the water absorption capacity of the PCA sodium is 1.5 times that of glycerin, 2 times that of propylene glycol and 6 times that of sorbitol; it has no toxicity, no irritation, good stability, and can make skin and hair have wettability, softness, elasticity, glossiness and antistatic property. PCA Na is an excellent skin whitening agent, has an inhibitory effect on the activity of tyrosine oxidase, and can prevent the deposition of "melanoid" in the skin, thereby whitening the skin. PCA Na can be used as cutin softening agent, and has good therapeutic effect on skin psoriasis. The sodium levorotatory lactate can form a hydration film with other chemical components to prevent the volatilization of skin moisture, so that the skin is in a high-quality and light moist state, wrinkles are prevented, and the sodium levorotatory lactate is widely used as a moisturizer of skin care products.
Preferably, the hair washing cream further comprises the following components in percentage by weight: 0.5-2% of camellia extract, 0.5-2% of sodium levorotatory lactate, 25-35% of dihydroxypropyl arginine HCl, 0.25-1% of saccharide isomer and 0.5-2% of sodium PCA. The sodium levorotatory lactate, the dihydroxypropyl arginine HCl, the saccharide isomer and the PCA sodium are added according to the proportion and can be matched with each other to form a moisture-preserving film layer on the surfaces of the scalp and the hair, so that the scalp acne bacteria can be reduced, the dandruff bacteria can be reduced, the oil can be reduced, the scalp pox can be reduced, and the scalp acne-preventing cream is helpful for fundamentally inhibiting the production of dandruff. More preferably, the hair washing cream further comprises the following components in percentage by weight: camellia extract 1%, sodium levorotatory lactate 1%, dihydroxypropyl arginine HCl 30%, saccharide isomer 0.5% and sodium PCA 1%.
Preferably, the hair washing cream further comprises the following components in percentage by weight: 40% of a mixture of sodium lauroyl lactylate, sodium laureth sulfate, sodium lauroyl glutamate and sodium lauroyl amphoacetate. Each surfactant component has good cleaning effect and low irritation.
Preferably, the hair washing cream further comprises the following components in percentage by weight: 0.2-0.6% of hydroxypropyl guar hydroxypropyl trimethyl ammonium chloride, 0.05-0.2% of allantoin, 0.01-0.1% of polyethylene glycol-14M, 1-5% of cetearyl alcohol, 0.1-0.5% of rosemary leaf oil and 0.01-0.2% of EDTA disodium.
Hydroxypropyl guar hydroxypropyltrimonium chloride provides improved wet combing performance and a particularly refreshing experience, with mild conditioning. It is recommended to use in light shampoos without losing hair bundle volume. The polyethylene glycol-14M can leave silky smooth and elegant hand feeling for hair or skin; the product wet combing performance is improved remarkably, and the hair is smooth and easy to comb; the foam density, fullness, stability and durability of the surfactant system are improved; improve the lubricity and low-temperature fluidity of the liquid product, and contribute to the improvement of the consistency of the product. The additives are beneficial to improving the use experience of the shampoo, and the formed shampoo cream is uniform and good in stability.
Preferably, the shampoo further comprises 0.5-2% of linoleamidopropyl PG-dimethyl ammonium chloride phosphate. The linoleamidopropyl PG-dimethyl ammonium chloride phosphate can be used as an antistatic agent to be added into shampoo.
In addition to the above explicitly specified ingredients, the hair lotion of the present invention may further comprise a perfume and a preservative.
The invention has the beneficial effects that: the invention provides a probiotic dandruff-removing shampoo. The inactivated lactobacillus paracasei is added to be used together with the soybean oil and the maltotetraose, which is beneficial to restoring the microecological balance of scalp flora and radically solving the dandruff problem.
Detailed Description
In the examples, all raw materials are purchased from the market, wherein the mixture of sodium lauroyl lactylate, sodium laureth sulfate, sodium lauroyl glutamate and sodium lauroyl amphoacetate is purchased from Qin Ying refining chemical company, Inc. in Guangzhou, and the product model is HR 60;
dihydroxypropyl arginine HCl was purchased from Nippon chemical and Chemicals, Inc. under the product designation Aminose R;
the inactivated lactobacillus paracasei is purchased from incubator GmbH of Shandong Zhongyi enterprises, and the product model is SCP-2;
a mixture of Magnolia rugosa (MAGNOLIA KOBUS) bark extract, Camellia sinensis (CAMELLIA SINENSIS) leaf extract, Citrus GRANDIS (Citrus GRANDIS) fruit extract, and Thujopsis dolabra (Thujopsis dolabra) branch extract was purchased from Korean BioSpectrum company under the model of Multi Ex magnetiticsTMIn the product, the weight percentage of the mixture of the magnolia winkle bark extract, the tea extract, the pomelo fruit extract and the Thujopsis dolabrata extract is 8-12%
The mixture of bis (hydroxymethyl) imidazolidinyl urea and iodopropynyl butylcarbamate was purchased from jjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjj.
To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.
Examples 1 to 6
The formula of the hair washing cream preparation raw materials of the embodiments 1-6 is shown in the table 1. The preparation method of the hair washing cream disclosed in the embodiment 1-6 comprises the following steps:
1. sequentially adding the raw materials A into a water phase pot, stirring and heating to 80-85 ℃, and then adding and stirring the raw materials A1 for 5 minutes until the raw materials are uniformly dispersed;
2. adding the mixed raw materials B into a water phase pot, stirring for 3 minutes, adding the raw materials C, stirring for 5 minutes until the raw materials are uniformly dispersed, and preserving heat for 10 minutes;
3. stirring in a water phase pot, cooling to about 40 deg.C, adding the D raw materials, and stirring for dispersing;
sampling at 4.38 ℃, detecting each physical and chemical index to be qualified, filtering and discharging to obtain the shampoo.
Table 1 preparation of hair lotions according to examples 1 to 6 raw material formulation (%)
Figure BDA0002281431120000051
Figure BDA0002281431120000061
Comparative examples 1 to 6
The formula of the raw materials for preparing the shampoo in comparative examples 1 to 6 is shown in Table 2. The preparation method of the hair washing cream described in comparative examples 1 to 6 is the same as that of examples 1 to 6.
Table 2 raw material formulation for hair washing cream preparation in comparative examples 1 to 6 (%)
Figure BDA0002281431120000062
Figure BDA0002281431120000071
Example 7
Clinical effect verification
Study subjects: has seborrheic dermatitis, dandruff, and scalp pruritus. 600 cases (300 men and 300 women) were divided into an example group (300 cases) and a comparative example group (300 cases) by a random number table method, each of which was 50 cases and was aged at an average age (35. + -. 0.5). The using method comprises the following steps: the probiotic anti-dandruff shampoo of the present example was used every three days, and the hair was washed using a conventional shampooing method for 8 weeks. The effect of use is shown in table 3.
And (3) judging standard:
obviously improve the following steps: after 8 weeks of use, the dandruff is obviously reduced, and the scalp is not itchy any more; and (3) relieving: after 8 weeks of use, the dandruff is reduced, and the interval time of scalp pruritus is prolonged; and (4) invalidation: neither dandruff nor itching was improved.
The 50 cases were recorded and reviewed and the results are shown in Table 3.
TABLE 3 use Effect of the hair lotions described in examples 1 to 6 and comparative examples 1 to 6
Group of Obviously improve Mitigation Invalidation Total effective rate
Example 1 19(38%) 29(58%) 2(4%) 96%
Example 2 11(22%) 32(64%) 7(14%) 86%
Example 3 14(28%) 31(62%) 5(10%) 90%
Example 4 15(30%) 29(58%) 6(12%) 88%
Example 5 13(26%) 31(62%) 6(12%) 88%
Example 6 15(30%) 30(60%) 3(6%) 90%
Comparative example 1 6(12%) 32(64%) 12(24%) 76%
Comparative example 2 9(18%) 31(62%) 10(20%) 80%
Comparative example 3 7(14%) 33(66%) 10(20%) 80%
Comparative example 4 10(20%) 32(64%) 8(16%) 84%
Comparative example 5 16(32%) 26(52%) 8(16%) 84%
Comparative example 6 12(24%) 30(60%) 8(16%) 84%
As can be seen from Table 3, the hair lotions of examples 1 to 6 can effectively improve the problems of scalp itching and dandruff, the effective rate is as high as over 85%, and the feedback of the use effect of example 1 is optimal. Compared with the example 1, the comparative examples 1 to 3 lack one or more of inactivated lactobacillus paracasei, maltotetraose and soybean oil, and the feedback of the using effect in the aspects of removing dandruff and relieving itching is far inferior to that in the example 1, which shows that the inactivated lactobacillus paracasei, maltotetraose and soybean oil can be cooperatively matched in the shampoo to play the effects of removing dandruff and relieving itching. Compared with the example 1, the comparative examples 4 to 6 lack several of levorotatory sodium lactate, dihydroxypropyl arginine HCl, saccharide isomer and PCA sodium, and the effects of removing dandruff and relieving itching are not as good as the example 1, probably because the components can be used together to better form a moisturizing film layer, inhibit acne bacteria on scalp and reduce the incidence rate of dandruff.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims (10)

1. The probiotic anti-dandruff shampoo is characterized by comprising inactivated lactobacillus paracasei, maltotetraose and soybean oil.
2. The probiotic antidandruff shampoo according to claim 1, characterized in that it comprises the following components in percentage by weight: 0.5-2% of inactivated lactobacillus paracasei, 0.5-2% of maltotetraose and 6-10% of soybean oil.
3. The probiotic antidandruff shampoo according to claim 1, characterized in that it comprises the following components in percentage by weight: 1% of inactivated lactobacillus paracasei, 1% of maltotetraose and 8% of soybean oil.
4. The probiotic anti-dandruff shampoo as claimed in claim 1, wherein the shampoo comprises 0.5-2% camellia extract and 0.4-0.6% of a mixture of magnolia rugosa bark extract, tea leaf extract, pomelo fruit extract and thujoram twig extract.
5. The probiotic anti-dandruff shampoo of any one of claims 1 to 4, further comprising at least one of sodium levolactate, dihydroxypropyl arginine HCl, saccharide isomers, and sodium PCA.
6. The probiotic antidandruff shampoo according to claim 5, further comprising the following components in percentage by weight: 0.5-2% of sodium levorotatory lactate, 0.25-35% of dihydroxypropyl arginine HCl25, 0.25-1% of saccharide isomer and 0.5-2% of sodium PCA.
7. The probiotic antidandruff shampoo according to claim 5, further comprising the following components in percentage by weight: sodium levorotatory lactate 1%, dihydroxypropyl arginine HCl 30%, saccharide isomer 0.5% and sodium PCA 1%.
8. The probiotic antidandruff shampoo according to claim 5, further comprising the following components in percentage by weight: 40% of a mixture of sodium lauroyl lactylate, sodium laureth sulfate, sodium lauroyl glutamate and sodium lauroyl amphoacetate.
9. The probiotic antidandruff shampoo according to claim 8, further comprising the following components in weight percent: 0.2-0.6% of hydroxypropyl guar hydroxypropyl trimethyl ammonium chloride, 0.05-0.2% of allantoin, 0.01-0.1% of polyethylene glycol-14M, 1-5% of cetearyl alcohol, 0.1-0.5% of rosemary leaf oil and 0.01-0.2% of EDTA disodium.
10. The probiotic antidandruff shampoo according to claim 9, further comprising 0.5-2% of linoleamidopropyl PG-dimethylammonium chloride phosphate.
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CN115300420A (en) * 2021-09-15 2022-11-08 上海兴博隆精细化工有限公司 Permanently-molded hair care composition and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN115300420A (en) * 2021-09-15 2022-11-08 上海兴博隆精细化工有限公司 Permanently-molded hair care composition and preparation method thereof
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CN114469842A (en) * 2021-12-31 2022-05-13 广州禾力生物科技有限公司 Composition for repairing scalp and application thereof in hair care comb

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