CN109125213A - It is a kind of to have Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect - Google Patents

It is a kind of to have Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect Download PDF

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Publication number
CN109125213A
CN109125213A CN201811210152.9A CN201811210152A CN109125213A CN 109125213 A CN109125213 A CN 109125213A CN 201811210152 A CN201811210152 A CN 201811210152A CN 109125213 A CN109125213 A CN 109125213A
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parts
extract
cream
inflammatory
agent
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刘海平
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Shenzhen Haiyue Biotechnology Co Ltd
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Shenzhen Haiyue Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
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    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
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    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
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    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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    • A61K8/86Polyethers
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    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
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    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
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    • A61K8/892Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a hydroxy group, e.g. dimethiconol
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    • A61K8/9761Cupressaceae [Cypress family], e.g. juniper or cypress
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    • A61K8/9794Liliopsida [monocotyledons]
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    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/002Preparations for repairing the hair, e.g. hair cure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/006Antidandruff preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61Q5/02Preparations for cleaning the hair

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Abstract

The invention discloses one kind Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect, it include the component of following mass fraction: 100-200 parts of water, 25-46 parts of surfactant, assign 3.5-10 parts of rouge agent, hair renovation agent and 1.05-2.5 parts of gloss agent, 2-4 parts of softener, 0.02-0.05 parts of PH regulator, 0.05-0.1 parts of chelating agent, 0.1-0.5 parts of freshener, 0.5-1.5 parts of preservative, 1-2 parts of odorant, 10-35 parts of the Chinese medicine factor, 0.5-1.5 parts of anti-dandruff and itching-relieving agent, skin condition, anti-aging with renovation agent 6-16 parts, clean hair-cream is set to play Sage Extract by said components, antibacterial anti-inflammatory and the effect for repairing scalp, to reach mild, safety, efficiently, lasting goes Consider effect to be worth doing.

Description

It is a kind of to have Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect
Technical field
The present invention relates to washing product technical fields, more particularly to one kind to have Sage Extract, antibacterial anti-inflammatory and reparation The clean hair-cream of scalp effect.
Background technique
Dandruff is that the metabolism that the skin epidermis epithelial cells of not vital activity constantly fall off from skin surface produces The epithelial cells of object, cuticula are linked together by intercellular structural, and the outermost epithelial cells of cuticula loosen, take off It falls, forms dandruff.It the regeneration of dandruff and falls off and is always to maintain certain stable state, if this balance is due to some Reason is broken, then may cause the relevant issues of dandruff.Although the relationship of dandruff and microorganism is not now also complete It is complete clear, it has been found that most important microorganism related to dandruff generation is chlosma (chaff Pi pityrosporion ovale).Health Scalp depends on the balance of finance, credits and materials, i.e. grease balance, colony balance, metabolic balance, and the generation of dandruff is destroyed with the balance of finance, credits and materials There is close connection.Chlosma is survived dependent on grease, therefore its growth scope is mostly the more flourishing region of grease body of gland, Such as the positions such as scalp, facial T-type area.When scalp grease balance be destroyed after, grease can a large amount of abnormal secretions, this is just horse It draws the breeding of color bacterium to provide environmental basis, will affect the metabolism of cell again when its mass propagation, that is, flora is unbalance Journey, and then break metabolic balance, lose intercellular connectivity, while the epithelial cells of a large amount of hyperplasias are accumulated and fallen off Form abnormal dandruff.The arch-criminal that the not all type dandruff of chlosma occurs, research find dandruff also and cuticula Free fatty acid, that cholesterol, ceramide levels such as are decreased obviously at the hormonal problems is related.In addition, such as solar exposure, no Suitable clean hair product, the pollutant component in air, the excessively environmental problems such as cleaning may all aggravate dandruff abnormal increase Occur.
To sum up, being good for whether grease balance, colony balance, metabolic balance this balance of finance, credits and materials are the key that scalp healths The scalp of health have maintain balance of finance, credits and materials state ability, once in the balance of finance, credits and materials it is one or more in vivo, it is bad in vitro It is broken under the influence of factor, various scalp health problems certainly will be will lead to.It is asked by the scalp health of representative of dandruff problem The problem of topic seriously affects health and personal image and appearance, while also bringing itch, mental health etc. etc..Solve head Scurf problem will surround and how assist scalp tissue to restore and maintain the balance of finance, credits and materials --- and grease balance, colony balance, metabolism are flat Weighing apparatus.Currently, it is most of it is anti-dandruff wash shield product in can all be added such as salicylic acid, zinc pyrithione, pyrroles gram ketone ethanolamine salt, Climbazole, selenium sulfide etc. commonly synthesize one of anti-dandruff agent or a variety of, these anti-dandruff agents, although can take in a short time Obvious effect is obtained, but also brings along some problems simultaneously, for example Antifungal resistance enhancing, human body generate dependence etc.. In order to overcome these disadvantages, Chinese medicine class washes shield product and starts more and more to appear in face of people.
It is found after retrieval, such as Chinese herbal medicine extract involved in the patent formulation of Publication No. CN103816092B.The power It is protected in sharp claim including Radix Angelicae Sinensis, kuh-seng, frutus cnidii, the tuber of stemona, cortex dictamni, yellow Kashiwa, the coptis, Radix Astragali, fructus viticis, Sang Bai The formula of the feedstock composition of the Chinese medical extracts such as skin, rhizome of chuanxiong.The invention is mainly for antibacterial and anti-dandruff two aspects.And this hair It is bright to be not merely directed to removal dandruff, also without being bound by antibacterial problem, but from the angle of scalp health, with the balance of finance, credits and materials For impetus, using the traditional Chinese medicine medication theory of " monarch " as foundation, choose it is various be applicable in, effective medicinal herb components or its Its plant component is to cooperate " monarch drug in a prescription " --- and stem cell releasing factor gives full play to the compatibility effect of each ingredient, makes scalp It is restored to the state of balance, health.Therefore, although the patent is with this patent have on medicinal herb components it is some be overlapped, still There is the difference of essence.
Such as patent of Publication No. CN103622862A again, although cacumen biotae which is related to, the fleece-flower root, Radix Angelicae Sinensis, The medicinal herb components relevant to this patent such as ginseng, but the active constituent that the invention mainly applies in light-coloured vinegar facilitates Chinese herbal medicine Pharmacological property, thus the effects of reaching anti-dandruff, dark hair, health care scalp, this is same as the principle of the invention to be essentially different.
Such as invention of Publication No. CN107213097A and publication number CN105496881A again, although being wherein respectively mentioned to The balance of finance, credits and materials and grease balance, but the invention of Publication No. CN107213097A does not illustrate its action principle, not to invention Effect carries out test or it is demonstrated experimentally that simply shows formula and simple technique.The hair of Publication No. CN105496881A Bright primary efficacy is exactly antibacterial action and promotion scalp blood circulation, the fleece-flower root being directed to, Radix Angelicae Sinensis, cortex dictamni, ginseng etc. Although four taste Chinese herbal medicines are also embodied in the present invention, these types of traditional Chinese medicine ingredients be not in the present invention mainly at Point, but the submember of booster action is played, and the present invention is the reparation and regeneration with stem cell factor to scalp cells Effect is core, and the invention with Publication No. CN105496881A is all not quite similar in principle and effect, similar There are also the patents of invention of Publication No. CN104414936A.
As stated above, it really is not able to solve the problems, such as therefore the technical solution of the balance of finance, credits and materials needs in the prior art It is a kind of it is effective, without dependence, have no toxic side effect with Sage Extract, antibacterial anti-inflammatory and repair scalp effect It is capable of the clean hair-cream of systemic the problems such as solving dandruff.
Summary of the invention
Shortcoming present in view of the above technology, the purpose of the present invention is to provide one kind Sage Extract, antibacterial Anti-inflammatory and the clean hair-cream for repairing scalp effect play Sage Extract, antibacterial anti-inflammatory by related effective component and repair head The effect of skin, to reach mild, safe and efficient, lasting anti-dandruff effect.
To achieve the above object, technical scheme is as follows.
It is a kind of to have Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect, it include following mass fraction Component:
100-200 parts of water, assigns 3.5-10 parts of rouge agent, hair renovation agent and gloss agent 1.05- at 25-46 parts of surfactant 2.5 parts, 2-4 parts of softener, 0.02-0.05 parts of PH regulator, 0.05-0.1 parts of chelating agent, 0.1-0.5 parts of freshener, preservative 0.5-1.5 parts, 1-2 parts of odorant, 10-35 parts of the Chinese medicine factor, 0.5-1.5 parts of anti-dandruff and itching-relieving agent, skin condition, anti-aging with repair It is agent 6-16 parts multiple.In the present invention, so that clean hair-cream is played Sage Extract, antibacterial anti-inflammatory by said components and repair scalp Effect, to reach mild, safe and efficient, lasting anti-dandruff effect.
Further, the water is deionized water, and the surfactant includes laureth sodium sulfovinate 15-25 Part, 3-8 parts of laurel alcohol sulfuric ester ammonium, 3-5 parts of Cocoamidopropyl betaine, MEA1-2 parts of coconut oleoyl amine, sodium xylene sulfonate 1-2 parts, -23 0.5-1.0 parts of laureth, -3 0.5-1.0 parts of C12-15 Pareth, C12-14 Pareth -3 0.5-1.0 parts, -9 0.5-1.0 parts of C12-14 Pareth.
Further, the tax rouge agent include 1-2 parts of glycol distearate, 0.5-1.0 parts of cetostearyl alcohol, 0.3-0.8 parts of C12-13 alcohol lactate;The softener includes 1-2 parts of dimethyl silicone polymer, dimethiconol 1-2 parts, 0.1-0.3 parts of guar hydroxypropyltrimonium chloride.
Further, the hair renovation agent and gloss agent include 0.3-1.0 parts of panthenol, 0.05-0.1 parts of lysine, 0.05-0.1 parts of histidine, 0.05-0.1 parts of arginine, 0.05-0.1 parts of aspartic acid, 0.05-0.1 parts of threonine, serine 0.05-0.1 parts, 0.05-0.1 parts of glutamic acid, 0.05-0.1 parts of proline, 0.05-0.1 parts of glycine, alanine 0.05-0.1 Part, 0.05-0.1 parts of valine, 0.05-0.1 parts of isoleucine, 0.05-0.1 parts of leucine, 0.05-0.1 parts of tyrosine, phenylpropyl alcohol 0.05-0.1 parts of propylhomoserin.
Further, the PH regulator includes 0.02-0.05 parts of citric acid;The chelating agent includes EDETATE SODIUM 0.05-0.1 parts;The freshener includes 0.1-0.5 parts of menthol;The preservative includes 0.5-1.5 parts of sodium salicylate; The odorant includes 1-2 parts of essence;
Further, the Chinese medicine factor includes that shrubby sophora extract, Radix Stemonae extract, Cortex Dictamni extract, yellow Kashiwa mention Take object, common cnidium fruit P.E, dandelion extract, Salvia root P.E, Cacumen Platycladi extract, Herba speranskiae tuberculatae extract, ramulus mori or mulberry Leaf extract, Fructus Gleditsiae Abnormalis extract, ginseng extract, radix-polygoni multiflori extract, angelica extract, apple extract, camellia seed extract One of object, oat extract are a variety of.
Further, the anti-dandruff and itching-relieving agent includes 0.5-1.5 parts of zinc pyrithione;The skin condition, anti-aging with Renovation agent includes 0.01-0.05 parts of stem cell composite factor, 0.01-0.03 parts of allantoin, 5-15 parts of bamboo leaching.
Further, the clean hair-cream further includes having 0.005-0.01 parts of cytolipin plastid, 0.5-0.8 parts of sodium chloride.
Further, it is described it is a kind of have Sage Extract, antibacterial anti-inflammatory and repair scalp effect clean hair-cream, include with The component of lower mass fraction:
100-200 parts of water, 15-25 parts of laureth sodium sulfovinate, 3-8 parts of laurel alcohol sulfuric ester ammonium, coconut oleoyl amine third 3-5 parts of base glycine betaine, 1-2 parts of glycol distearate, 1-2 parts of dimethyl silicone polymer, 1-2 parts of coconut oleoyl amine MEA, pyrrole 0.5-1.5 parts of sulphur zinc, 1-2 parts of sodium xylene sulfonate, 1-2 parts of dimethiconol, -23 0.5-1.0 of laureth Part, -30.5-1.0 parts of C12-15 Pareth, -3 0.5-1.0 parts of C12-14 Pareth, C12-14 Pareth - 90.5-1.0 parts, 0.5-1.0 parts of cetostearyl alcohol, 0.3-1.0 parts of panthenol, 0.3-0.8 parts of C12-13 alcohol lactate, lysine 0.05-0.1 parts, 0.05-0.1 parts of histidine, 0.05-0.1 parts of arginine, 0.05-0.1 parts of aspartic acid, threonine 0.05- 0.1 part, 0.05-0.1 parts of serine, 0.05-0.1 parts of glutamic acid, 0.05-0.1 parts of proline, 0.05-0.1 parts of glycine, third 0.05-0.1 parts of propylhomoserin, 0.05-0.1 parts of valine, 0.05-0.1 parts of isoleucine, 0.05-0.1 parts of leucine, tyrosine 0.05-0.1 parts, 0.05-0.1 parts of phenylalanine, 0.1-0.3 parts of guar hydroxypropyltrimonium chloride, sodium salicylate 0.5- 1.5 parts, 0.02-0.05 parts of citric acid, 0.1-0.5 parts of menthol, 0.5-0.8 parts of sodium chloride, 0.05-0.1 parts of EDETATE SODIUM, perfume 1-2 parts smart, 0.01-0.05 parts of stem cell composite factor, 0.005-0.01 parts of cytolipin plastid, 0.01-0.03 parts of allantoin, in 10-35 parts of the medicine factor, 5-10 parts of bamboo leaching, the Chinese medicine factor include shrubby sophora extract, Radix Stemonae extract, cortex dictamni extraction Object, yellow Kashiwa extract, common cnidium fruit P.E, dandelion extract, Salvia root P.E, Cacumen Platycladi extract, Herba speranskiae tuberculatae extract, Ramulus mori or mulberry-leaf extract, Fructus Gleditsiae Abnormalis extract, ginseng extract, radix-polygoni multiflori extract, angelica extract, apple extract, mountain One of tea seed extract, oat extract are a variety of.
The present invention also provides a kind of preparation sides for having Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect Method, comprising the following steps:
Step 1: it according to the various raw materials of formula ratio precise, is held with vessel that are clean and disinfecting;
Step 2: by water, laureth sodium sulfovinate, laurel alcohol sulfuric ester ammonium, Cocoamidopropyl betaine, second two Alcohol distearate, coconut oleoyl amine MEA, sodium xylene sulfonate, cetostearyl alcohol, panthenol, C12-13 alcohol lactate, melon rubber hydroxyl Hydroxypropyltrimonium chloride, EDETATE SODIUM are added in agitated kettle, and stirring is warming up to 85~90 DEG C, and stirring is opened cold to after being completely dissolved But water cools down;
Step 3: when being cooled to 40-45 DEG C, be added dimethyl silicone polymer, zinc pyrithione, dimethiconol, Laureth -23, C12-14 Pareth -3, C12-14 Pareth -9, relies ammonia at C12-15 Pareth -3 It is acid, histidine, arginine, aspartic acid, threonine, serine, glutamic acid, proline, glycine, alanine, valine, different Leucine, leucine, tyrosine, phenylalanine, guar hydroxypropyltrimonium chloride, sodium salicylate, the Chinese medicine factor, lemon Acid, menthol, sodium chloride, EDETATE SODIUM, bamboo leaching, stem cell composite factor, cytolipin plastid, allantoin, essence sufficiently stir Discharging, standing after mixing uniformly, filling finished product, the Chinese medicine factor include shrubby sophora extract, Radix Stemonae extract, cortex dictamni extraction Object, yellow Kashiwa extract, common cnidium fruit P.E, dandelion extract, Salvia root P.E, Cacumen Platycladi extract, Herba speranskiae tuberculatae extract, Ramulus mori or mulberry-leaf extract, Fructus Gleditsiae Abnormalis extract, ginseng extract, radix-polygoni multiflori extract, angelica extract, apple extract, mountain One of tea seed extract, oat extract are a variety of.
In the present invention, laureth sodium sulfovinate: it is soluble easily in water, have excellent decontamination, emulsification, foam performance and Hard water resistance performance, biological degradability are good.
Laurel alcohol sulfuric ester ammonium: belong to anionic surfactant.It is soluble easily in water, tool good with anion, nonionic compatibility There are good emulsification, foaming, infiltration, decontamination and dispersion performance.
Cocoamidopropyl betaine: amphoteric surfactant, have it is good cleaning, blistering, opsonic action, with yin from Son, cation and nonionic surfactant compatibility are good;And irritation is small, performance is mild, and foam is fine and smooth and stablizes, and is applicable in In configuration shampoo, shower cream, facial cleanser etc., the flexibility to hair, skin can be enhanced.Match with appropriate anionic surfactant Wu Shi has apparent thickening effect, also acts as conditioner, wetting agent, fungicide, antistatic agent etc..
Coconut oleoyl amine MEA: degradable.With excellent decontamination, emulsification, foaming, foam stabilizing, dispersion, solubilising power.With excellent Good calcium and magnesium dispersibility.
Sodium xylene sulfonate: for making solubilizer in detergent, the component of dry cleaning agent, fungicide, intermetallic composite coating are also served as Cleaning agent etc..Sodium xylene sulfonate is used in liquid detergent, can be used as coupling agent, hydrotropic agent, levelling agent, dispersing agent, And make cloud point, viscosity decline.
Laureth -23: surfactant, remover, emulsifier, toner class product can be more smooth after being added, There is certain foaming characteristic.
C12-15 Pareth -3: has the function of emulsifier.
C12-14 Pareth -3: has the function of emulsifier.
C12-14 Pareth -9: has the function of emulsifier.
Glycol distearate: using can produce apparent pearl effect in liquid washing products, and it can increase production The viscosity of product also has skin care, hair care hair care and antistatic property.
Cetostearyl alcohol: surfactant, emulsifier, hydrophily thickening agent, from palm, the fatty alcohol of coco, It is commonly used for the products such as face cream, leaves shampoo.
C12-13 alcohol lactate: skin emollient.
Panthenol: moisturizer, skin conditioner, antistatic agent, oxidizable, water-soluble, alcohol and propylene glycol are inhaled through skin It after receipts, works with vitamin B6 one, skin sodium hyaluronate content can be increased, have the function of making skin gloss and moisturizing, can pierce Swash cell division regeneration and repair tissue, is especially suitable for ripe age skin and uses.
Stem cell composite factor: being mixed more than 200 kinds of polypeptides from the vesica of human umbilical cord mesenchymal stem cells secretion Object is closed, has the function of that skin is activated to be sunk into sleep aging stem cell, promotes skin progenitor cell self-renewing and differentiation, supplement skin histology Required cell and extracellular matrix.
Lysine, histidine, arginine, aspartic acid, threonine, serine, glutamic acid, proline, glycine, the third ammonia The amino acid such as acid, valine, isoleucine, leucine, tyrosine, phenylalanine provide various necessary ammonia to repair scalp Base acid.
Dimethiconol: silication polymer is usually used in hair washing, profit hair product, can increase compliance, and will not produce Oil generation soapy feeling.
Dimethyl silicone polymer: having greasy property, anti-ultraviolet effect, and good permeability has apparent dust-proof function Can, also it is used to replace traditional glyceride stock in cosmetics, this is that have preferable flexibility according to dimethyl silicone polymer Characteristic usually can be all used in moisture retention product in skin care item.
Citric acid: for adjusting pH value.
Weak organic acid mainly obtains (especially lemon) from citrus fruit, is the tart flavour source of part food or beverage, And it can be used as natural antiseptic agent.
EDETATE SODIUM: mineral sequestration agent can cooperate with antisepsis.
Sodium salicylate: preservative has the function of certain removal cutin and relieves the pain, and has anti-inflammatory efficacy.
Traditional Chinese medicine ingredients: kuh-seng, antioxidant, skin conditioner;The tuber of stemona inhibits odorant agent, skin protective agent;Cortex dictamni, It is clearing heat and detoxicating, there is antibacterial action;Yellow Kashiwa, antibacterial, anti-eczema and cutitis are anti-oxidant;Frutus cnidii, antiallergy are antimycotic;Dandelion, With sterilization and bacteriostasis effect, antioxidant, prevention scytitis and other effects.As allergy inhibitor, anatrophic and hair restorer;It is red Ginseng improves microcirculation, and wound healing is anti-oxidant, anti-fibrosis;Cacumen biotae, cool blood, growing and blacking hair;Lopseed, anti-inflammatory, Sterilization, the convergence surface of a wound;Ramulus mori (leaf) extract, anti-inflammatory, antibacterial is antiviral, improves immunity, removes free radical anti-aging;Gleditsia sinensis, Decontamination and antibacterial action are cleaned in emulsification;Ginseng, emollients, skin and hair conditioner, nourishing effect;The fleece-flower root, skin condition Agent has and moistens hair, plays a role in hair root, prevents epilation and effect that is anti-oxidant and delaying senescence;When Return, promote blood circulation, improves skin;Apple extract, inhibit elastomer ferment destroy elastomer, reduce skin by The injury of free radical and anti-aging;Camellia (seed) extract, lubrication, sterilization and it is antipruritic;Oat extract, it is grinding agent, anti-oxidant Agent, emollients, skin conditioner.
Zinc pyrithione (zinc pyrithione): the compound of this zinc is used as topical antifungal agents or antibacterial agent.It can inhibit leather Lan Shi feminine gender, positive bacteria and fungus growth, there is stronger sterilizing ability, can kill the fungi for generating dandruff.Zinc pyrithione It can with bamboo leaching, frutus cnidii, yellow Kashiwa, lopseed, ramulus mori (leaf) extract, gleditsia sinensis, camellia (seed) extract etc. in traditional Chinese medicine ingredients With play Sage Extract, antibacterial anti-inflammatory, moderately removing dandruff effect ingredient collective effect, as anti-dandruff and itching-relieving agent.
Stem cell composite factor includes following component: BFGF (Basic Fibroblast Growth Factor): fibroblast being promoted to close At the extracellular mechanism molecule such as collagen;EGF (epidermal growth factor): active cell repairs epidermis;KGF (cutin growth factor): Promote the growth of Eponychium cell, repairs impaired skin;I GF (insulin-like growth factor): promote cytothesis reparation;VEGF (vascular endothelial growth factor): improving blood circulation, and endothelial cell is promoted to be converted to skin cell;ANG (angiogenesis Element): the integrality and normal update of blood vessel are maintained, microcirculation, ruddy skin are improved;L IF9 (LIF ELISA): promote Into stem cells self-renewal;EPO (hematopoietin): promote Regeneration and Repair;SDF-1 (stroma cell derivative factor): it inhales Draw the stem cell in blood to skin, promotes the update and Regeneration and Repair of skin;PDGF (platelet derived growth factor): stimulation Fibroblast, vascular endothelial cell and smooth muscle cell division growth, promote the reparation of skin;FGF4.6.7.9 is (at fibre Tie up growth factor 4 .6.7.9): promote vascular repair, fibroblast proliferation and generates the extracellular matrix molecules such as collagen.Increase The elasticity of skin accelerates tissue repair;BNDF (brain-derived nerve growth factor): neurotrophic effect;Promote vascularization and Regeneration and restoration;GDNF (glial cell line-derived neurotrophic factor);Other ingredients (more than 200 kinds of related activities growths because Son);Essence is natural perfume material.
Allantoin: being a kind of amphoteric compound, can in conjunction with other substances formed double salt, have sun-proof, sterilization, anti-corrosion, analgesic, The effects of anti-oxidant, also has effects that water lock moisturizing.
Bamboo leaching: containing there are many active skull cap components, such as flavone compound, de lta- oxylysine, super oxygen Object mutase etc. has free radical in outstanding removing skin, free radical resisting, anti-aging, moisturizing convergence, anti-corrosion, antibacterial, beautiful White, anti-inflammatory and other effects.
Cytolipin plastid: as the delivery vehicle of other effective components of stem cell factor, i.e., by drug encapsulation in lipoids The miniature vesicle formed in bilayer, effect are to carry effective component to enter cell interior.
The beneficial effects of the present invention are: compared with prior art, one kind provided by the invention has Sage Extract, antibacterial anti-inflammatory And the clean hair-cream of scalp effect is repaired, Sage Extract, antibacterial anti-inflammatory are played by related effective component and repairs scalp Effect, to reach mild, safe and efficient, lasting anti-dandruff effect;Wherein, it is effectively gone out by the bactericidal effect of zinc pyrithione Kill and inhibit the fungal microbes such as the chlosma for leading to seborrheic dermatitis;In addition, Cocoamidopropyl betaine and diformazan Benzene sulfonic acid sodium salt has certain bactericidal effect;For grease, using a variety of high-efficiency cleanings, degreasing and performance it is mild surface it is living Property agent, achievees the effect that efficient degreasing, salubrious scalp;For head caused by some other reasons such as dust and ultraviolet light etc. Scurf, dimethiconol and dimethyl silicone polymer in formula can act as lubrication, dust-proof and anti-purple well Outside line function;Solving the problems, such as will also be by the effect of some nutritional ingredients and stem cell factor after the grease of scalp and flora Make scalp cells activity recovery and function and interior environment and stable state is made to reach relative ideal and stable health status, to balance Scalp flora simultaneously repairs damaged cell, is inherently eliminated the inducement of dandruff generation.
Specific embodiment
In order to which the purpose of the present invention, technical solution and beneficial effect is more clearly understood, the present invention is carried out further It is described in detail.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to limit this hair It is bright.
It is a kind of to have Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect, it include following mass fraction Component:
100-200 parts of water, assigns 3.5-10 parts of rouge agent, hair renovation agent and gloss agent 1.05- at 25-46 parts of surfactant 2.5 parts, 2-4 parts of softener, 0.02-0.05 parts of PH regulator, 0.05-0.1 parts of chelating agent, 0.1-0.5 parts of freshener, preservative 0.5-1.5 parts, 1-2 parts of odorant, 10-35 parts of the Chinese medicine factor, 0.5-1.5 parts of anti-dandruff and itching-relieving agent, skin condition, anti-aging with repair It is agent 6-16 parts multiple.In the present invention, so that clean hair-cream is played Sage Extract, antibacterial anti-inflammatory by said components and repair scalp Effect, to reach mild, safe and efficient, lasting anti-dandruff effect.
In the present embodiment, water is deionized water, surfactant include 15-25 parts of laureth sodium sulfovinate, 3-8 parts of laurel alcohol sulfuric ester ammonium, 3-5 parts of Cocoamidopropyl betaine, MEA1-2 parts of coconut oleoyl amine, sodium xylene sulfonate 1-2 Part, -23 0.5-1.0 parts of laureth, -3 0.5-1.0 parts of C12-15 Pareth, C12-14 Pareth -3 0.5-1.0 parts, -9 0.5-1.0 parts of C12-14 Pareth.
In the present embodiment, assign rouge agent include 1-2 parts of glycol distearate, 0.5-1.0 parts of cetostearyl alcohol, 0.3-0.8 parts of C12-13 alcohol lactate;Softener includes 1-2 parts of dimethyl silicone polymer, dimethiconol 1-2 Part, 0.1-0.3 parts of guar hydroxypropyltrimonium chloride.
In the present embodiment, hair renovation agent and gloss agent include 0.3-1.0 parts of panthenol, 0.05-0.1 parts of lysine, 0.05-0.1 parts of histidine, 0.05-0.1 parts of arginine, 0.05-0.1 parts of aspartic acid, 0.05-0.1 parts of threonine, serine 0.05-0.1 parts, 0.05-0.1 parts of glutamic acid, 0.05-0.1 parts of proline, 0.05-0.1 parts of glycine, alanine 0.05-0.1 Part, 0.05-0.1 parts of valine, 0.05-0.1 parts of isoleucine, 0.05-0.1 parts of leucine, 0.05-0.1 parts of tyrosine, phenylpropyl alcohol 0.05-0.1 parts of propylhomoserin.
In the present embodiment, PH regulator includes 0.02-0.05 parts of citric acid;Chelating agent includes EDETATE SODIUM 0.05-0.1 parts;Freshener includes 0.1-0.5 parts of menthol;Preservative includes 0.5-1.5 parts of sodium salicylate;Odorant packet 1-2 parts of essence are included.
In the present embodiment, the Chinese medicine factor includes that shrubby sophora extract, Radix Stemonae extract, Cortex Dictamni extract, yellow Kashiwa mention Take object, common cnidium fruit P.E, dandelion extract, Salvia root P.E, Cacumen Platycladi extract, Herba speranskiae tuberculatae extract, ramulus mori or mulberry Leaf extract, Fructus Gleditsiae Abnormalis extract, ginseng extract, radix-polygoni multiflori extract, angelica extract, apple extract, camellia seed extract One of object, oat extract are a variety of.
In the present embodiment, anti-dandruff and itching-relieving agent includes 0.5-1.5 parts of zinc pyrithione;Skin condition, anti-aging and reparation Agent includes 0.01-0.05 parts of stem cell composite factor, 0.01-0.03 parts of allantoin, 5-15 parts of bamboo leaching.
In the present embodiment, clean hair-cream further includes having 0.005-0.01 parts of cytolipin plastid, 0.5-0.8 parts of sodium chloride.
In the present embodiment, it is a kind of have Sage Extract, antibacterial anti-inflammatory and repair scalp effect clean hair-cream, include with The component of lower mass fraction:
100-200 parts of water, 15-25 parts of laureth sodium sulfovinate, 3-8 parts of laurel alcohol sulfuric ester ammonium, coconut oleoyl amine third 3-5 parts of base glycine betaine, 1-2 parts of glycol distearate, 1-2 parts of dimethyl silicone polymer, 1-2 parts of coconut oleoyl amine MEA, pyrrole 0.5-1.5 parts of sulphur zinc, 1-2 parts of sodium xylene sulfonate, 1-2 parts of dimethiconol, -23 0.5-1.0 of laureth Part, -30.5-1.0 parts of C12-15 Pareth, -3 0.5-1.0 parts of C12-14 Pareth, C12-14 Pareth - 90.5-1.0 parts, 0.5-1.0 parts of cetostearyl alcohol, 0.3-1.0 parts of panthenol, 0.3-0.8 parts of C12-13 alcohol lactate, lysine 0.05-0.1 parts, 0.05-0.1 parts of histidine, 0.05-0.1 parts of arginine, 0.05-0.1 parts of aspartic acid, threonine 0.05- 0.1 part, 0.05-0.1 parts of serine, 0.05-0.1 parts of glutamic acid, 0.05-0.1 parts of proline, 0.05-0.1 parts of glycine, third 0.05-0.1 parts of propylhomoserin, 0.05-0.1 parts of valine, 0.05-0.1 parts of isoleucine, 0.05-0.1 parts of leucine, tyrosine 0.05-0.1 parts, 0.05-0.1 parts of phenylalanine, 0.1-0.3 parts of guar hydroxypropyltrimonium chloride, sodium salicylate 0.5- 1.5 parts, 0.02-0.05 parts of citric acid, 0.1-0.5 parts of menthol, 0.5-0.8 parts of sodium chloride, 0.05-0.1 parts of EDETATE SODIUM, perfume 1-2 parts smart, 0.01-0.05 parts of stem cell composite factor, 0.005-0.01 parts of cytolipin plastid, 0.01-0.03 parts of allantoin, in 10-35 parts of the medicine factor, 5-15 parts of bamboo leaching, the Chinese medicine factor include shrubby sophora extract, Radix Stemonae extract, Cortex Dictamni extract, Yellow Kashiwa extract, common cnidium fruit P.E, dandelion extract, Salvia root P.E, Cacumen Platycladi extract, Herba speranskiae tuberculatae extract, mulberry Branch or mulberry-leaf extract, Fructus Gleditsiae Abnormalis extract, ginseng extract, radix-polygoni multiflori extract, angelica extract, apple extract, camellia One of seed extract, oat extract are a variety of.
The present invention also provides a kind of preparation sides for having Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect Method, comprising the following steps:
Step 1: it according to the various raw materials of formula ratio precise, is held with vessel that are clean and disinfecting;
Step 2: by water, laureth sodium sulfovinate, the laurel alcohol sulfuric ester ammonium, cocamidopropyl propyl amide sweet tea in raw material Dish alkali, glycol distearate, coconut oleoyl amine MEA, sodium xylene sulfonate, cetostearyl alcohol, panthenol, C12-13 alcohol lactic acid Ester, guar hydroxypropyltrimonium chloride, EDETATE SODIUM are added in agitated kettle, and stirring is warming up to 85~90 DEG C, stir to complete Cooling water temperature is opened after fully dissolved;
Step 3: when being cooled to 40-45 DEG C, be added dimethyl silicone polymer, zinc pyrithione, dimethiconol, Laureth -23, C12-14 Pareth -3, C12-14 Pareth -9, relies ammonia at C12-15 Pareth -3 It is acid, histidine, arginine, aspartic acid, threonine, serine, glutamic acid, proline, glycine, alanine, valine, different Leucine, leucine, tyrosine, phenylalanine, guar hydroxypropyltrimonium chloride, sodium salicylate, the Chinese medicine factor, lemon Acid, menthol, sodium chloride, EDETATE SODIUM, bamboo leaching, stem cell composite factor, cytolipin plastid, allantoin, essence sufficiently stir Mix uniformly after discharging, stand, filling finished product, the Chinese medicine factor include shrubby sophora extract, Radix Stemonae extract, Cortex Dictamni extract, Yellow Kashiwa extract, common cnidium fruit P.E, dandelion extract, Salvia root P.E, Cacumen Platycladi extract, Herba speranskiae tuberculatae extract, mulberry Branch or mulberry-leaf extract, Fructus Gleditsiae Abnormalis extract, ginseng extract, radix-polygoni multiflori extract, angelica extract, apple extract, camellia One of seed extract, oat extract are a variety of.
The beneficial effects of the present invention are: compared with prior art, one kind provided by the invention has Sage Extract, antibacterial anti-inflammatory And the clean hair-cream of scalp effect is repaired, Sage Extract, antibacterial anti-inflammatory are played by related effective component and repairs scalp Effect, to reach mild, safe and efficient, lasting anti-dandruff effect;Wherein, it is effectively gone out by the bactericidal effect of zinc pyrithione It kills and inhibits to lead to the chlosma of seborrheic dermatitis and psoriasis etc. fungal microbe;In addition, cocamidopropyl propyl amide sweet tea Dish alkali and sodium xylene sulfonate have certain bactericidal effect;For grease, using a variety of high-efficiency cleanings, degreasing and performance temperature The surfactant of sum achievees the effect that efficient degreasing, salubrious scalp;For some other reasons such as dust and ultraviolet light The dandruff Deng caused by, dimethiconol and dimethyl silicone polymer in formula can act as well lubrication, Dust-proof and anti-ultraviolet function;Solving the problems, such as will also be by some nutritional ingredients and stem cell after the grease of scalp and flora The effect of the factor makes scalp cells activity recovery and function and interior environment and stable state is made to reach relative ideal and stable healthy shape State is inherently eliminated the inducement of dandruff generation to balance scalp flora and repair damaged cell.
The clean hair-cream for having Sage Extract, antibacterial anti-inflammatory and reparation scalp effect is carried out below in conjunction with specific embodiment It illustrates.
The present invention, which provides, a kind of effective does not have dependence and what is had no toxic side effect has Sage Extract, balance bacterium Group and the clean hair-cream for repairing scalp effect.Clean hair product on the market is largely from physics cleaning even deep physical at present Clean angle targetedly removes grease, then be aided with salicylic acid, zinc pyrithione, pyrroles gram ketone ethanolamine salt, Climbazole, One or more synthesis anti-dandruff agents being widely used such as selenium sulfide are killed by its stronger instant bactericidal effect and cause dandruff Microorganism to reach more apparent anti-dandruff effect in a short time.But inevitably, it is this kind of wash shield product can be to scalp The balance of finance, credits and materials causes different degrees of influence or injury even scalp to be made to generate dependence to it.Opposite, Chinese herbal medicine extract Or although other plant effective component has many advantages, such as that pharmacological property is mild, toxic side effect is small, conditioning scalp, maintenance hair, if single It is pure to have the shortcomings that slow effect, short run effect are undesirable again to symptoms such as dandruff, itching of the scalps using Chinese herbal medicine extract.So being Overcoming this disadvantage, we take and synthesize anti-dandruff agent using zinc pyrithione etc. in right amount and other plant extract is mutually matched Method, to cooperate with repair cell, promote the stem cell factor of cell division effect, so that product be made to reach short-term, long The all quite apparent effect of phase effect, while also avoiding largely being likely to result in adverse effect and generation using synthesis anti-dandruff agent The defect of dependence.In severe dandruff patient, Excessive seborrhea goes out and seborrhea is very common illness, these diseases In disease, the keratoderma of patient is frequently subjected to excessively to clean or the influence of inflammation secondary, erythema and microlesion occurs Phenomenon.We targetedly develop this product in view of the above problems.Its major function is exactly to balance flora, Sage Extract With reparation scalp.These three aspects are not independent, play the role of it is mutually coordinated, each other in table, with stem cell factor Reparation and palingenesis to scalp cells are core, some with mild bactericidal antiphlogistic effect and the mild Chinese medicine of pharmacological property mentions It takes object and naturally goes under the booster action of oil component fundamentally to solve or improve various scalp problems.Specifically, in dandruff In problem, by studying the mechanism of action of chlosma, a set of effective theoretical method is targetedly proposed, i.e., first benefit With the natural surfactant and synthetic surfactant collective effect of suitable dosage, controls seborrhea and reduce chlosma Quantity, then cooperate with medicinal herb components mildly to sterilize by the zinc pyrithione of suitable dosage, anti-inflammatory, finally in stem cell factor Effect is lower to repair damaged scalp tissue, restores metabolic balance.It works on the three areas simultaneously, scalp is made to get well, reach health three are big flat Weighing apparatus state.By to specific crowd study for a long period of time and experimental data is concluded, we have concluded that four kinds of implementable cases, are being protected It emphasizes particularly on different fields again under the premise of the basic role of card Sage Extract, antibacterial anti-inflammatory and reparation scalp, takes into account long-term and go in short term Consider effect to be worth doing.This systematic solution is different from most similar products currently on the market.
Embodiment 1
Step 1: it according to the various raw materials of formula ratio precise, is held with vessel that are clean and disinfecting;
Step 2: by water, laureth sodium sulfovinate, the laurel alcohol sulfuric ester ammonium, cocamidopropyl propyl amide sweet tea in raw material Dish alkali, glycol distearate, coconut oleoyl amine MEA, sodium xylene sulfonate, cetostearyl alcohol, panthenol, C12-13 alcohol lactic acid Ester, guar hydroxypropyltrimonium chloride, EDETATE SODIUM are added in agitated kettle, and stirring is warming up to 85~90 DEG C, stir to complete Cooling water temperature is opened after fully dissolved;
Step 3: when being cooled to 40-45 DEG C, be added dimethyl silicone polymer, zinc pyrithione, dimethiconol, Laureth -23, C12-14 Pareth -3, C12-14 Pareth -9, relies ammonia at C12-15 Pareth -3 It is acid, histidine, arginine, aspartic acid, threonine, serine, glutamic acid, proline, glycine, alanine, valine, different Leucine, leucine, tyrosine, phenylalanine, guar hydroxypropyltrimonium chloride, sodium salicylate, the Chinese medicine factor, lemon Acid, menthol, sodium chloride, EDETATE SODIUM, bamboo leaching, stem cell composite factor, cytolipin plastid, allantoin, essence sufficiently stir It is spare after discharging, standing after mixing uniformly.
Wherein, the Chinese medicine factor include 1 part of Cacumen Platycladi extract, 2 parts of shrubby sophora extracts, 2 parts of Salvia root P.Es, 3 parts what Tuber of multiflower knotweed extract, 6 parts of apple extracts, 2 parts of yellow Kashiwa extracts, 4 parts of angelica extracts, 3 parts of oat extracts, 1 part of frutus cnidii Extract, 2 parts of dandelion extracts, 1 part of Herba speranskiae tuberculatae extract, 4 parts of mulberry leaf (branch) extracts, 2 parts of Fructus Gleditsiae Abnormalis extracts, 1 part of mountain Tea (seed) extract, 3 parts of Cortex Dictamni extracts, 4 parts of ginseng extracts;
Wherein, bamboo leaching is 10 parts, and stem cell factor is 0.01 part, and zinc pyrithione is 0.8 part, lysine, histidine, essence Propylhomoserin, aspartic acid, threonine, serine, glutamic acid, proline, glycine, alanine, valine, isoleucine, bright ammonia It is 1.5 parts that acid, tyrosine, phenylalanine, which have altogether,.
Embodiment 2
Preparation method is same as Example 1.
Wherein, the Chinese medicine factor includes 1 part of shrubby sophora extract, 1 part of Salvia root P.E, 2 parts of radix-polygoni multiflori extracts, 2 parts of apples Berry extract, 1 part of yellow Kashiwa extract, 2 parts of oat extracts, 1 part of dandelion extract, 1 part of Herba speranskiae tuberculatae extract, 3 parts of mulberry leaf (branch) extract, 2 parts of Fructus Gleditsiae Abnormalis extracts, 2 parts of camellia (seed) extracts, 2 parts of ginseng extracts;
Wherein, stem cell factor is 0.04 part, and zinc pyrithione is 0.6 part, lysine, histidine, arginine, asparagus fern ammonia Acid, threonine, serine, glutamic acid, proline, glycine, alanine, valine, isoleucine, leucine, tyrosine, benzene It is 1.5 parts that alanine, which has altogether,.
Embodiment 3
Preparation method is same as Example 1.
Wherein, the Chinese medicine factor includes 1 part of Salvia root P.E, 2 parts of radix-polygoni multiflori extracts, 3 parts of apple extracts, 1 portion of swallow Wheat extract, 2 parts of mulberry leaf (branch) extracts, 1 part of Fructus Gleditsiae Abnormalis extract, 1 part of camellia (seed) extract, 1 part of ginseng extract;
Wherein, bamboo leaching is 5 parts, and stem cell factor is 0.05 part, and zinc pyrithione is 0.5 part, lysine, histidine, essence Propylhomoserin, aspartic acid, threonine, serine, glutamic acid, proline, glycine, alanine, valine, isoleucine, bright ammonia It is 1.5 parts that acid, tyrosine, phenylalanine, which have altogether,.
Embodiment 4
Preparation method is same as Example 1.
Wherein, the Chinese medicine factor includes 2 parts of Cacumen Platycladi extracts, 2 parts of Salvia root P.Es, 4 parts of radix-polygoni multiflori extracts, 2 parts Apple extract, 2 parts of angelica extracts, 2 parts of Radix Stemonae extracts, 3 parts of dandelion extracts, 3 parts of camellia (seed) extracts, 2 parts Cortex Dictamni extract, 3 parts of ginseng extracts;
Wherein, bamboo leaching is 6 parts, and stem cell factor is 0.02 part, and zinc pyrithione is 0.7 part, lysine, histidine, essence Propylhomoserin, aspartic acid, threonine, serine, glutamic acid, proline, glycine, alanine, valine, isoleucine, bright ammonia It is 1.5 parts that acid, tyrosine, phenylalanine, which have altogether,.
Reference examples 5
Reference examples 5 are not add the check experiment case of stem cell factor, and other compositions are referring to embodiment 1-4.
Wherein, the Chinese medicine factor include 1 part of Cacumen Platycladi extract, 2 parts of shrubby sophora extracts, 2 parts of Salvia root P.Es, 3 parts what Tuber of multiflower knotweed extract, 5 parts of apple extracts, 2 parts of yellow Kashiwa extracts, 1 part of angelica extract, 3 parts of oat extracts, 1 part of frutus cnidii Extract, 2 parts of dandelion extracts, 1 part of Herba speranskiae tuberculatae extract, 4 parts of mulberry leaf (branch) extracts, 2 parts of Fructus Gleditsiae Abnormalis extracts, 1 part of mountain Tea (seed) extract, 3 parts of Cortex Dictamni extracts, 4 parts of ginseng extracts;
Wherein, bamboo leaching is 7 parts, and zinc pyrithione is 0.8 part, lysine, histidine, arginine, aspartic acid, Soviet Union's ammonia Acid, serine, glutamic acid, proline, glycine, alanine, valine, isoleucine, leucine, tyrosine, phenylalanine It is 1.5 parts altogether.
Reference examples 6
Reference examples 6 are not add the check experiment case of stem cell factor, and other compositions are referring to embodiment 1-4.
Wherein, the Chinese medicine factor includes 1 part of shrubby sophora extract, 1 part of Salvia root P.E, 2 parts of radix-polygoni multiflori extracts, 2 parts of apples Berry extract, 1 part of yellow Kashiwa extract, 2 parts of oat extracts, 1 part of dandelion extract, 1 part of Herba speranskiae tuberculatae extract, 3 parts of mulberry leaf (branch) extract, 2 parts of Fructus Gleditsiae Abnormalis extracts, 2 parts of camellia (seed) extracts, 2 parts of ginseng extracts;
Wherein, zinc pyrithione is 0.6 part, lysine, histidine, arginine, aspartic acid, threonine, serine, paddy ammonia It is 1.5 parts that acid, proline, glycine, alanine, valine, isoleucine, leucine, tyrosine, phenylalanine, which have altogether,.
Reference examples 7
Reference examples 7 are not add the check experiment case of stem cell factor, and other compositions are referring to embodiment 1-4.
Wherein, the Chinese medicine factor includes 1 part of Salvia root P.E, 2 parts of radix-polygoni multiflori extracts, 3 parts of apple extracts, 1 portion of swallow Wheat extract, 2 parts of mulberry leaf (branch) extracts, 1 part of Fructus Gleditsiae Abnormalis extract, 1 part of camellia (seed) extract, 1 part of ginseng extract;
Wherein, bamboo leaching is 5 parts, and zinc pyrithione is 0.5 part, lysine, histidine, arginine, aspartic acid, Soviet Union's ammonia Acid, serine, glutamic acid, proline, glycine, alanine, valine, isoleucine, leucine, tyrosine, phenylalanine It is 1.5 parts altogether.
Reference examples 8
Reference examples 8 are not add the check experiment case of stem cell factor, and other compositions are referring to embodiment 1-4.
Wherein, the Chinese medicine factor includes 2 parts of Cacumen Platycladi extracts, 2 parts of Salvia root P.Es, 4 parts of radix-polygoni multiflori extracts, 2 parts Apple extract, 2 parts of angelica extracts, 2 parts of Radix Stemonae extracts, 3 parts of dandelion extracts, 3 parts of camellia (seed) extracts, 2 parts Cortex Dictamni extract, 3 parts of ginseng extracts;
Wherein, bamboo leaching is 6 parts, and zinc pyrithione is 0.7 part, lysine, histidine, arginine, aspartic acid, Soviet Union's ammonia Acid, serine, glutamic acid, proline, glycine, alanine, valine, isoleucine, leucine, tyrosine, phenylalanine It is 1.5 parts altogether.
Reference examples 9
Reference examples 9 are to be added without bamboo leaching, stem cell factor, zinc pyrithione, lysine, histidine, arginine, asparagus fern ammonia Acid, threonine, serine, glutamic acid, proline, glycine, alanine, valine, isoleucine, leucine, tyrosine, benzene The preparation of alanine and any Chinese medicine factor, other compositions are referring to embodiment 1-4.
Reference examples 10
Reference examples 10 are the clean hair product of Chinese medicine class in the prior art.
Table 1 is the effective component contrast table of embodiment 1-4 and reference examples 1-6
It is A-D by product number prepared by above-described embodiment 1-4;Product number prepared by reference examples 5-10 is E-J. Principle active component is only shown in the above case.Embodiment 1-4 is obtained by long-felt and experience accumulation for balance The several embodiments that grease, antibacterial anti-inflammatory and reparation scalp etc. are most effective, resultant effect is best.
The practical effect of experimental verification experimental group and control group will be passed through below
Experimental principle: contain the practical effect of the clean hair-cream of different formulations by experimental verification.Control mode: blank Control, mutually control, matched control.
Test independent variable:
The case study on implementation 1-4 that number is A-D is experimental group;The comparison case 5-10 that number is E-J is control group
Test dependent variable:
α, be not used product on the day before, using after product 45 days and stop using this product and change commercially available routine it is non-in The clean hair product of medicine class dandruff severity scale after 45 days.Due to being directed to the ununified judgement mark of dandruff in the world at present Standard, therefore we are more common " ten grades of point systems of adherence dandruff " using foreign study, remarks are shown in criterion;
The subjective use feeling of β, experimental subjects.Reference factor includes: dandruff, itching of the scalp, scalp is fuel-displaced, scalp is red Spot, dry scalp, color development etc. six.
Every group of physical record number is 5 people, totally 10 groups.Experiment is made to exclude the gap of experimental subjects individual age as far as possible At other influences, while in order to more highlight experiment effect, the experimental subjects that this experimental group is chosen is de- with obvious dandruff Fall phenomenon.In order to facilitate the combination of observation heterogeneity to the effect of patient, according to the statistics of " ten grades of point systems of adherence dandruff " The scoring of the every potential head bits patient of canonical statistics, and it is divided into 5 grades (specific grouping situation is shown in remarks) according to statistical result, it calculates Out the patient of each grade each experimental group average and to carry out appropriate adjustment to experimental subjects flat to meet experimental subjects The reasonability and intuitive of equal quantity, while recording the subjective use feeling of each phase experiments participant.To meet control as far as possible The requirement of variable, experimental subjects chose age distribution at 25-30 years old, and men and women is fifty-fifty, exhorts that experimental subjects is kept away as far as possible during test To exempt to eat greasy pungent irritable food, clean hair-cream usage amount, frequency of use, use condition are controlled in the same terms as far as possible, and Physical fitness is close between experimental subjects, and experiment starts first three days and forbids experimental subjects using any clean hair product, before experiment starts Daystart observation.
Experiment one
Verify case study on implementation, comparison case and certain market fast sale brand similar product practical effect.
Remarks: in following table 2-table 4,
[0] " 0 " grade is indicated;[1] " 1-2 " grade is indicated;[2] " 3-4 " grade is indicated;[3] " 5-6 " grade is indicated;[4] indicate "≤ 7 " grades
0 grade indicates no dandruff, and 1-2 grades are the greyish white rough scales of small flakes, and 3-4 grades are as low as median size chip, 5-6 Grade for the loose big and thin chip being connected of scalp, 7-8 grade be big tackness chip, 9-10 grades be and scalp close attachment The white thicker scales of skin that peel off to yellow.
Participating in experiment total number of persons is 80 people, 72 people of actual acquisition information content, 50 people of real application data amount, every group of 5 people. Data are initiated direction experiment participant by experiment and are collected, and record experiment starts the statistical data of the previous day.It is above after data-optimized The total quantity of 5 grades is respectively as follows: 0 people, 10 people, 30 people, 10 people, 0 people;Averagely arrive the experiment pair of each grade of each experimental group As number are as follows: 0 people, 1 people, 3 people, 1 people, 0 people.
Table 2 is the scalp situation comparison of the experimenter on the day before using A-J respectively number product
Table 3 is to be compared using the scalp situation of the experimenter after A-J respectively number product 45 days
Table 4 is to be compared using the scalp situation after using instead after the 46th day other a certain common commercially available clean hairs product 45 days
Test each stage subjectivity use feeling of two experimental subjects
Experiment two participation total number of persons be 80 people, 69 people of actual acquisition information content, 50 people of real application data amount, every group 5 people.Data participate in this ballot by experiment and obtain, and experiment the previous day record voting results simultaneously carry out data-optimized and grouping.
Statistical result is as shown in following table 5- table 7:
Table 5 is the number percentage of the scalp sense organ of the experimenter on the day before using A-J respectively number product
Table 6 is the number percentage using the scalp sense organ of the experimenter after A-J respectively number product 45 days
Dandruff Itching of the scalp Scalp is fuel-displaced Scalp erythema Dry scalp Hair quality is short-tempered
A1 0% 0% 0% 20% 0% 20%
B1 0% 0% 0% 0% 0% 20%
C1 0% 0% 0% 0% 0% 0%
D1 0% 0% 0% 20% 0% 0%
E1 0% 20% 20% 20% 0% 20%
F1 0% 20% 0% 20% 20% 0%
G1 20% 20% 0% 0% 20% 0%
H1 0% 0% 20% 0% 40% 0%
I1 80% 40% 40% 40% 80% 100%
J1 0% 0% 20% 0% 20% 0%
Table 7 is the number percentage of the scalp sense organ after being used instead other a certain common commercially available clean hairs product 45 days using the 46th day Than
Dandruff Itching of the scalp Scalp is fuel-displaced Scalp erythema Dry scalp Hair quality is short-tempered
A1 0% 0% 20% 0% 20% 0%
B1 0% 0% 0% 0% 0% 0%
C1 0% 0% 0% 0% 0% 0%
D1 0% 0% 20% 0% 0% 0%
E1 20% 60% 40% 20% 20% 20%
F1 40% 40% 20% 0% 0% 20%
G1 40% 40% 20% 0% 40% 40%
H1 20% 0% 0% 0% 40% 20%
I1 80% 60% 40% 60% 60% 80%
J1 40% 40% 60% 20% 40% 40%
Data analysis:
1. by table 2 in experiment one, in table 3 six groups of experimental results such as A, B, C, D, I, J it is found that the present invention compared with certain popular brand The short run effect of the commercially available clean hair product of Chinese medicine class has some superiority, but gap is not obvious.But it is any effective compared to being added without The I group of ingredient, the present invention and condition control group J have more apparent effect.It is found that by long-term practice, exploration, improving The case study on implementation 1~4 arrived has preferable short run effect.
2. by table 3 in experiment one, in table 4 six groups of experimental results such as A, B, C, D, I, J it is found that stopping using production of the present invention Product use another mainstream instead routinely after clean hair product after 45 days, and there is no obvious rebounds for the dandruff phenomenon of A~D group;Correspondingly , certain popular brand product is stopped using, uses another mainstream instead routinely after the clean hair product of non-Chinese medicine class after 45 days, it can be observed that More apparent rebound phenomena;Additionally by self-controlled group E~H group of stem cell factor, (A and E are one group, and B and F are one Group, and so on) data it is found that the product of stem cell factor is not added also have rebound phenomena for the long-term effect of dandruff, It follows that case study on implementation 1~4 also has preferable long-term effect, illustrate that it promotes scalp to restore normally to adjust with certain The effect of section header skin stable state, and then it could be assumed that --- stem cell factor for repair scalp tissue, restore cell and activity, It assists scalp to restore stable state to be of great significance.
3. for experiment participant about in the experiment for using subjective feeling in experiment two, by table 5, table 6 in experiment two Six groups of experimental results such as middle A, B, C, D, I, J it is found that the present invention compared with certain popular clean hair product of the commercially available Chinese medicine class of brand short-term effect Fruit has slight advantages, but gap is not obvious.But compared to the I group for being added without any effective component, the present invention is compareed with condition Group J has more apparent effect.The statistical result with it is objective experiment one in data first coincide.
4. by table 6 in experiment two, in table 7 six groups of experimental results such as A, B, C, D, I, J it is found that stopping using production of the present invention Product use another mainstream instead routinely after clean hair product after 45 days, and there is no obvious rebounds for the dandruff phenomenon of A~D group;Correspondingly , certain popular brand product is stopped using, another mainstream is used instead routinely after clean hair product after 45 days, it can be observed that more obviously Rebound phenomena, especially fuel-displaced three indexs of dandruff, itching of the scalp, scalp are the most obvious;Additionally by stem cell factor Control group E~H group data also have rebound phenomena for the long-term effect of dandruff it is found that the product of stem cell factor is not added. Wherein, dandruff, itching of the scalp dry scalp, three it is more obvious, it follows that the formula of case study on implementation 1~4 have it is certain Promote scalp restore normal regulating scalp stable state effect, and then it could be assumed that --- stem cell factor for repair scalp group It knits, restores cell and activity, scalp recovery stable state is assisted to be of great significance.
The above is only several preferred embodiments of the invention, are not intended to limit the invention, it is all in spirit of the invention and Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within principle.

Claims (10)

  1. It include the group of following mass fraction 1. a kind of have Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect Point:
    100-200 parts of water, assigns 3.5-10 parts of rouge agent, hair renovation agent and gloss agent 1.05-2.5 at 25-46 parts of surfactant Part, 2-4 parts of softener, 0.02-0.05 parts of PH regulator, 0.05-0.1 parts of chelating agent, 0.1-0.5 parts of freshener, preservative 0.5-1.5 parts, 1-2 parts of odorant, 10-35 parts of the Chinese medicine factor, 0.5-1.5 parts of anti-dandruff and itching-relieving agent, skin condition, anti-aging with repair It is agent 6-16 parts multiple.
  2. 2. according to claim 1 have Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect, feature exists It is deionized water in the water, the surfactant includes 15-25 parts of laureth sodium sulfovinate, laurel alcohol sulfuric ester 3-8 parts of ammonium, 3-5 parts of Cocoamidopropyl betaine, MEA1-2 parts of coconut oleoyl amine, 1-2 parts of sodium xylene sulfonate, laruyl alcohol are poly- - 230.5-1.0 parts of ether, -30.5-1.0 parts of C12-15 Pareth, -30.5-1.0 parts of C12-14 Pareth, C12-14 - 90.5-1.0 parts of Pareth.
  3. 3. according to claim 1 have Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect, feature exists In the tax rouge agent include 1-2 parts of glycol distearate, 0.5-1.0 parts of cetostearyl alcohol, C12-13 alcohol lactate 0.3-0.8 parts;The softener includes 1-2 parts of dimethyl silicone polymer, 1-2 parts of dimethiconol, melon rubber hydroxyl 0.1-0.3 parts of hydroxypropyltrimonium chloride.
  4. 4. according to claim 1 have Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect, feature exists In the hair renovation agent and gloss agent include 0.3-1.0 parts of panthenol, 0.05-0.1 parts of lysine, histidine 0.05-0.1 Part, 0.05-0.1 parts of arginine, 0.05-0.1 parts of aspartic acid, 0.05-0.1 parts of threonine, 0.05-0.1 parts of serine, paddy ammonia 0.05-0.1 parts sour, 0.05-0.1 parts of proline, 0.05-0.1 parts of glycine, 0.05-0.1 parts of alanine, valine 0.05- 0.1 part, 0.05-0.1 parts of isoleucine, 0.05-0.1 parts of leucine, 0.05-0.1 parts of tyrosine, phenylalanine 0.05-0.1 Part.
  5. 5. according to claim 1 have Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect, feature exists In the PH regulator include 0.02-0.05 parts of citric acid;The chelating agent includes 0.05-0.1 parts of EDETATE SODIUM;It is described Freshener includes 0.1-0.5 parts of menthol;The preservative includes 0.5-1.5 parts of sodium salicylate;The odorant includes There are 1-2 parts of essence.
  6. 6. according to claim 1 have Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect, feature exists It include that shrubby sophora extract, Radix Stemonae extract, Cortex Dictamni extract, yellow Kashiwa extract, frutus cnidii extract in the Chinese medicine factor Object, dandelion extract, Salvia root P.E, Cacumen Platycladi extract, Herba speranskiae tuberculatae extract, ramulus mori or mulberry-leaf extract, gleditsia sinensis mention Take object, ginseng extract, radix-polygoni multiflori extract, angelica extract, apple extract, camellia seed extract, in oat extract It is one or more.
  7. 7. according to claim 1 have Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect, feature exists In the anti-dandruff and itching-relieving agent include 0.5-1.5 parts of zinc pyrithione;The skin condition, anti-aging and renovation agent include dry thin 0.01-0.05 parts of born of the same parents' composite factor, 0.01-0.03 parts of allantoin, 5-15 parts of bamboo leaching.
  8. 8. according to claim 1 have Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect, feature exists It further include having 0.005-0.01 parts of cytolipin plastid, 0.5-0.8 parts of sodium chloride in the clean hair-cream.
  9. 9. according to claim 1 have Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect, feature exists In the component for including following mass fraction:
    100-200 parts of water, 15-25 parts of laureth sodium sulfovinate, 3-8 parts of laurel alcohol sulfuric ester ammonium, cocamidopropyl propyl amide sweet tea 3-5 parts of dish alkali, 1-2 parts of glycol distearate, 1-2 parts of dimethyl silicone polymer, 1-2 parts of coconut oleoyl amine MEA, pyrrole sulphur 0.5-1.5 parts of zinc, 1-2 parts of sodium xylene sulfonate, 1-2 parts of dimethiconol, -230.5-1.0 parts of laureth, - 30.5-1.0 parts of C12-15 Pareth, -3 0.5-1.0 parts of C12-14 Pareth, C12-14 Pareth - 90.5-1.0 parts, 0.5-1.0 parts of cetostearyl alcohol, 0.3-1.0 parts of panthenol, 0.3-0.8 parts of C12-13 alcohol lactate, lysine 0.05-0.1 parts, 0.05-0.1 parts of histidine, 0.05-0.1 parts of arginine, 0.05-0.1 parts of aspartic acid, threonine 0.05- 0.1 part, 0.05-0.1 parts of serine, 0.05-0.1 parts of glutamic acid, 0.05-0.1 parts of proline, 0.05-0.1 parts of glycine, third 0.05-0.1 parts of propylhomoserin, 0.05-0.1 parts of valine, 0.05-0.1 parts of isoleucine, 0.05-0.1 parts of leucine, tyrosine 0.05-0.1 parts, 0.05-0.1 parts of phenylalanine, 0.1-0.3 parts of guar hydroxypropyltrimonium chloride, DMDM hydantoin 0.3-0.5 parts, 0.02-0.05 parts of citric acid, 0.1-0.5 parts of menthol, 0.5-0.8 parts of sodium chloride, EDETATE SODIUM 0.05-0.1 Part, 1-2 parts of essence, 0.01-0.05 parts of stem cell composite factor, 0.005-0.01 parts of cytolipin plastid, allantoin 0.01-0.03 Part, 10-35 parts of the Chinese medicine factor, 5-15 parts of bamboo leaching, the Chinese medicine factor includes shrubby sophora extract, Radix Stemonae extract, shaggy-fruited dittany Bark extract, yellow Kashiwa extract, common cnidium fruit P.E, dandelion extract, Salvia root P.E, Cacumen Platycladi extract, lopseed Extract, ramulus mori or mulberry-leaf extract, Fructus Gleditsiae Abnormalis extract, ginseng extract, radix-polygoni multiflori extract, angelica extract, apple mention Take one of object, camellia seed extract, oat extract or a variety of.
  10. 10. a kind of preparation for having Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect according to claim 9 Method, comprising the following steps:
    Step 1: various raw materials are weighed according to formula ratio, are held with vessel;
    Step 2: by water, laureth sodium sulfovinate, laurel alcohol sulfuric ester ammonium, Cocoamidopropyl betaine, ethylene glycol two Stearate, coconut oleoyl amine MEA, sodium xylene sulfonate, cetostearyl alcohol, panthenol, C12-13 alcohol lactate, melon rubber hydroxypropyl Trimethyl ammonium chloride, EDETATE SODIUM are added in agitated kettle, and stirring is warming up to 85~90 DEG C, and stirring opens cooling water to after being completely dissolved Cooling;
    Step 3: when being cooled to 40-45 DEG C, dimethyl silicone polymer, zinc pyrithione, dimethiconol, laurel is added Alcohol polyethers -23, C12-15 Pareth -3, C12-14 Pareth -3, C12-14 Pareth -9, lysine, group Propylhomoserin, arginine, aspartic acid, threonine, serine, glutamic acid, proline, glycine, alanine, valine, different bright ammonia Acid, leucine, tyrosine, phenylalanine, guar hydroxypropyltrimonium chloride, sodium salicylate, the Chinese medicine factor, citric acid, Menthol, sodium chloride, EDETATE SODIUM, bamboo leaching, stem cell composite factor, cytolipin plastid, allantoin, essence are sufficiently stirred It is even after discharging, stand, filling finished product, the Chinese medicine factor include shrubby sophora extract, Radix Stemonae extract, Cortex Dictamni extract, Yellow Kashiwa extract, common cnidium fruit P.E, dandelion extract, Salvia root P.E, Cacumen Platycladi extract, Herba speranskiae tuberculatae extract, mulberry Branch or mulberry-leaf extract, Fructus Gleditsiae Abnormalis extract, ginseng extract, radix-polygoni multiflori extract, angelica extract, apple extract, camellia One of seed extract, oat extract are a variety of.
CN201811210152.9A 2018-10-17 2018-10-17 It is a kind of to have Sage Extract, antibacterial anti-inflammatory and the clean hair-cream for repairing scalp effect Pending CN109125213A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110652484A (en) * 2019-11-04 2020-01-07 武汉赛锐希斯科技有限公司 Shampoo formula for daily maintenance of psoriasis skin
CN110876695A (en) * 2019-11-20 2020-03-13 广州瑞誉化工科技有限公司 Probiotic dandruff-removing shampoo
CN112057371A (en) * 2020-09-27 2020-12-11 新疆大德恒生物股份有限公司 Apricot kernel hair-growing cream, composition and preparation method thereof
CN112516043A (en) * 2020-12-11 2021-03-19 贵州理工学院 A Chinese medicinal shampoo with effects of blackening hair, promoting hair growth, relieving itching and removing dandruff
CN115607463A (en) * 2022-10-27 2023-01-17 广州羿丞生物科技有限公司 Composition for preventing or treating scalp seborrheic dermatitis and application thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110652484A (en) * 2019-11-04 2020-01-07 武汉赛锐希斯科技有限公司 Shampoo formula for daily maintenance of psoriasis skin
CN110876695A (en) * 2019-11-20 2020-03-13 广州瑞誉化工科技有限公司 Probiotic dandruff-removing shampoo
CN112057371A (en) * 2020-09-27 2020-12-11 新疆大德恒生物股份有限公司 Apricot kernel hair-growing cream, composition and preparation method thereof
CN112516043A (en) * 2020-12-11 2021-03-19 贵州理工学院 A Chinese medicinal shampoo with effects of blackening hair, promoting hair growth, relieving itching and removing dandruff
CN115607463A (en) * 2022-10-27 2023-01-17 广州羿丞生物科技有限公司 Composition for preventing or treating scalp seborrheic dermatitis and application thereof

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