CN110859893A

CN110859893A - External prescription for treating pig sarcoptidosis and preparation method thereof

Info

Publication number: CN110859893A
Application number: CN201911313808.4A
Authority: CN
Inventors: 邓红玉; 黄静; 梁世仁; 陈凌锋; 吴有林
Original assignee: Jiangxi Aoxin Biotechnology Co Ltd; Fujian Aonong Biological Technology Group Co Ltd
Current assignee: Jiangxi Aoxin Biotechnology Co Ltd; Fujian Aonong Biological Technology Group Co Ltd
Priority date: 2019-12-18
Filing date: 2019-12-18
Publication date: 2020-03-06

Abstract

The embodiment of the application provides an external prescription for treating pig sarcoptidosis and a preparation method thereof, and relates to the field of Chinese herbal medicine preparations. The external prescription for treating the pig sarcoptidosis comprises the following raw materials in parts by weight: 18-30 parts of walnut leaves, 10-20 parts of patrinia, 10-25 parts of herba hyperici japonici and 5-15 parts of mint. A topical preparation for treating pig sarcoptidosis is prepared by decocting raw materials in water to obtain decoction, filtering, and concentrating to obtain liquid medicine. The external prescription for treating the pig sarcoptidosis has good treatment effect on the pig sarcoptidosis, is non-toxic, harmless and residue-free to human and livestock, cannot generate drug resistance, and is low in cost.

Description

External prescription for treating pig sarcoptidosis and preparation method thereof

Technical Field

The application relates to the field of Chinese herbal medicine preparations, in particular to an external prescription for treating pig sarcoptidosis and a preparation method thereof.

Background

The pig sarcoptidosis is a chronic contact skin disease caused by parasitic sarcoptidosis in pig skin, the clinical manifestations of the pig sarcoptidosis are red spots, severe itching, pustules and the like on the skin of a sick pig, and if the disease condition of the sick pig is serious, the sick pig can die. In recent years, with the continuous development and progress of the pig breeding industry, the incidence rate of the pig sarcoptidosis shows a rising trend, and the economic benefit of farmers is seriously influenced.

A plurality of medicinal preparations for treating the pig sarcoptidosis appear on the market, the treatment methods are different, the existing treatment medicines comprise trichlorfon, amitraz, ivermectin and the like, and although the treatment effects of the medicines are good, the medicines have large dosage, high cost, toxic and side effects and low safety and are limited in application.

Therefore, the research and development of the treatment medicine which is nontoxic, harmless and residue-free to human and livestock, does not generate drug resistance and has low cost has wide application prospect.

Disclosure of Invention

The purpose of the embodiment of the application is to provide an external prescription for treating the pig sarcoptidosis and a preparation method thereof, the external prescription has good treatment effect on the pig sarcoptidosis, is nontoxic, harmless and residue-free to human and livestock, cannot generate drug resistance, and is low in cost.

In a first aspect, the embodiment of the application provides an external prescription for treating pig sarcoptidosis, which comprises the following raw materials in parts by weight: 18-30 parts of walnut leaves, 10-20 parts of patrinia, 10-25 parts of herba hyperici japonici and 5-15 parts of mint.

According to the technical scheme, the walnut leaves, the patrinia, the herba hyperici japonici, the mint and the like are used as raw materials, and the external prescription for treating the pig sarcoptidosis can be prepared according to a certain dosage, contains a plurality of Chinese herbal medicine components, is mainly used for preventing and treating the pig sarcoptidosis, and is suitable for treating the pig sarcoptidosis in various stages. Wherein, the walnut leaves are leaves of plant juglans mandshurica maxim, have certain insecticidal activity, can treat psoriasis and tinea capitis, and have certain curative effect on the treatment of sarcoptidosis; herba Patriniae is whole plant or root of Ixeris denticulata of Compositae, and has antiinflammatory and antipruritic effects. The herba Sambuci Adnatae is whole plant or root bark of herba Sambuci Adnatae of Caprifoliaceae, and has antifungal effect; mentholum, also known as "YINDANGCAO", is a dry whole herb of Labiatae plant, and can be used for treating skin rubella and pruritus, and carbuncle, cellulitis, scabies, tinea, and dermatitis. The walnut leaves, the patrinia and the tetrandra leucocephala are used as main effective components, the walnut leaves, the patrinia and the tetrandra leucocephala have a main effect on treating the pig scabies, and have no effect of radically treating the pig scabies, although the walnut leaves have a treatment effect on the scabies, the patrinia and the tetrandra leucocephala do not have the assistance of anti-inflammation and antibacterial effects, so that the effect of radically treating the pig scabies is difficult to achieve; the mint is added, the cool and refreshing itching relieving effect can be achieved after the mint is used by the sick livestock, the mint does not irritate the skin when the mint is used by the sick livestock, the stress response is reduced, the mint can be applied to the affected part to comprehensively treat the pig sarcoptidosis, and the operation is simple. The walnut leaves, the patrinia, the herba hyperici japonici and the mint are combined together to play a synergistic role, and the deficiency is not enough. In addition, the external prescription has cooling and itching relieving effects on various pruritus skin diseases of the pigs, and has wide effects. The product of this application adopts the chinese herbal medicine to make, and the raw materials are easily obtained, can save the cost, and economical and practical can avoid remaining the harm to environment and people because of using the animal remedy, and the product does not have toxic and side effect, can not produce drug resistance, and sick pig licks and stings the affected part and also can not cause the poisoning.

In one possible implementation mode, the raw materials comprise the following components in parts by weight: 22-27 parts of walnut leaves, 14-17 parts of patrinia, 16-20 parts of herba hyperici japonici and 8-12 parts of mint.

In the technical scheme, the walnut leaves, the patrinia, the sambucus chinensis and the mint are used according to the dosage proportion, and have good synergistic effect, so that the pig sarcoptidosis is effectively treated.

In a possible implementation mode, the raw materials also comprise 10-20 parts of camphor by weight.

In the technical scheme, the raw materials can also be added with camphor, the camphor is granular crystals obtained by distilling roots, branches, leaves and waste materials of Lauraceae Lauraria, and can treat pruritus, scabies and stubborn dermatitis, and the camphor can be cooperated with other raw materials, thereby more effectively treating the pig scabies.

In a possible implementation mode, the raw materials further comprise 15-18 parts by weight of camphor.

In the technical scheme, the camphor with a certain dosage proportion is added into the raw materials, so that the mutual inhibition of the effect of the camphor and other raw materials can be avoided, if the dosage of the camphor is too large, the effect of other raw materials is not obvious, and if the dosage of the camphor is too small, the effect of the camphor is not obvious.

In a possible implementation mode, the raw materials further comprise 10-20 parts of radix angelicae by weight.

In the technical scheme, the raw materials can also be added with dahurian angelica root which is the dry root of dahurian angelica root or dahurian angelica root of hangzhou angelica of umbelliferae, the dahurian angelica root has the effects of reducing swelling and expelling pus, and the dahurian angelica root can act with other raw materials in a synergistic manner, so that the pig sarcoptidosis can be treated more quickly and effectively.

In a possible implementation mode, the raw materials further comprise 13-15 parts of radix angelicae by weight.

In the technical scheme, the camphor is added into the raw materials in a certain dosage proportion, so that the synergistic effect of the raw materials can be exerted.

In a second aspect, the present application provides a preparation method of the external prescription for treating pig sarcoptidosis provided in the first aspect, the raw materials are decocted with water, filtered and concentrated to obtain a liquid medicine.

In the technical scheme, the effective components in the Chinese herbal medicines can be extracted by adopting the simple process, and the Chinese herbal medicines are smeared on an affected part, are convenient to use and can effectively treat the pig sarcoptidosis.

In one possible implementation, the mass ratio of the raw material to the water is 1: 5-10, decocting for 1-3 hours.

In the technical scheme, the raw materials are decocted for a certain time by adding water according to the dosage ratio, so that effective components for treating the pig sarcoptidosis in the raw materials can be extracted.

In one possible implementation, the filtering is performed by using 3-5 layers of gauze.

In the technical scheme, the medicine residues can be filtered by adopting a plurality of layers of gauze for filtration, and the effective components are kept in the liquid medicine.

In one possible implementation, the volume ratio before and after concentration is 100-: 2; optionally, the medicinal liquid is dried to obtain medicinal powder.

In the technical scheme, the concentration of the effective components in the liquid medicine obtained by concentration according to the proportion is moderate, and the liquid medicine can be directly smeared for use; the medicinal liquid can also be dried into medicinal powder for easy storage.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions of the embodiments of the present application will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.

The external preparation for treating sarcoptidosis and the preparation method thereof according to the embodiment of the present application will be specifically described below.

The embodiment of the application provides an external prescription for treating pig sarcoptidosis, which comprises the following raw materials in parts by weight: 18-30 parts of walnut leaves, 10-20 parts of patrinia, 10-25 parts of herba hyperici japonici and 5-15 parts of mint; optionally, the raw materials comprise, by weight: 22-27 parts of walnut leaves, 14-17 parts of patrinia, 16-20 parts of herba hyperici japonici and 8-12 parts of mint. Illustratively, the raw materials comprise 18 parts of walnut leaves, 10 parts of herba patriniae, 25 parts of herba hyperici japonici and 15 parts of mint in parts by weight; or the raw materials comprise 30 parts of walnut leaves, 20 parts of herba patriniae, 10 parts of herba hyperici japonici and 8 parts of mint according to the parts by weight; or the raw materials comprise 22 parts of walnut leaves, 17 parts of herba patriniae, 16 parts of herba hyperici japonici and 12 parts of mint according to the parts by weight; or the raw materials comprise 27 parts of walnut leaves, 14 parts of herba patriniae, 20 parts of herba hyperici japonici and 8 parts of mint according to the parts by weight; or the raw materials comprise 25 parts of walnut leaves, 16 parts of herba patriniae, 18 parts of herba hyperici japonici and 10 parts of mint according to parts by weight.

In some embodiments of the present application, the raw material further comprises 10-20 parts of camphor or 10-20 parts of angelica dahurica.

In other embodiments of the present application, the raw materials further include 10-20 parts of camphor and 10-20 parts of angelica dahurica, that is, the raw materials include, by weight: 18-30 parts of walnut leaves, 10-20 parts of patrinia, 10-25 parts of sambucus chinensis, 5-15 parts of mint, 10-20 parts of camphor and 10-20 parts of angelica dahurica. Optionally, the raw materials comprise, by weight: 22-27 parts of walnut leaves, 14-17 parts of patrinia, 16-20 parts of herba hyperici japonici, 8-12 parts of mint, 15-18 parts of camphor and 13-15 parts of radix angelicae. Illustratively, the raw materials comprise 18 parts of walnut leaves, 10 parts of patrinia, 25 parts of sambucus chinensis, 15 parts of mint, 17 parts of camphor and 15 parts of angelica dahurica in parts by weight; or the raw materials comprise 30 parts of walnut leaves, 20 parts of patrinia, 10 parts of herba hyperici japonici, 8 parts of mint, 16 parts of camphor and 16 parts of angelica dahurica according to the parts by weight; or the raw materials comprise 22 parts of walnut leaves, 15 parts of herba patriniae, 18 parts of herba hyperici japonici, 12 parts of mint, 18 parts of camphor and 15 parts of radix angelicae; or the raw materials comprise 27 parts of walnut leaves, 16 parts of patrinia, 20 parts of herba hyperici japonici, 8 parts of mint, 16 parts of camphor and 13 parts of radix angelicae; or the raw materials comprise, by weight, 25 parts of walnut leaves, 16 parts of patrinia, 18 parts of herba hyperici japonici, 10 parts of mint, 17 parts of camphor and 14 parts of radix angelicae.

In a second aspect, the present application provides a preparation method of the external preparation for treating pig sarcoptidosis provided in the first aspect, the raw materials are decocted in water, the decoction is obtained by filtering, and then the decoction is concentrated to obtain a liquid medicine, the liquid medicine can be used as the external preparation of a liquid agent and directly applied to an affected part for use, and the liquid medicine can also be dried to form a medicinal powder, namely the external preparation of powder, and the medicinal powder is added with water and uniformly stirred and then applied to the affected part for use. In order to realize industrial production, the mass ratio of the raw materials to the water is 1: 5-10, such as 1: 5. 1: 8 or 1: decocting (boiling) for 1-3 hours, such as 1 hour, 2 hours, or 3 hours; the filtering mode is to adopt 3-5 layers of gauze for filtering, and the filtering aperture is generally 5-15 μm, such as 10 μm; the volume ratio of the filtered decoction to the liquid medicine is 100-500: 2, such as 100: 2. 150: 2. 300, and (2) 300: 2. 400: 2 or 500: 2.

the features and properties of the present application are described in further detail below with reference to examples.

Walnut leaves, patrinia, sambucus chinensis, mint, camphor and angelica dahurica used in the examples are all purchased from drugstores.

Example 1

This example provides a drug solution, which is prepared by the following preparation method:

preparing raw materials: 22g of walnut leaves, 14g of herba patriniae, 16g of herba hyperici japonici, 8g of mint, 15g of camphor and 13g of radix angelicae, and the total weight is 88 g; mixing the raw materials in a mass ratio of 1: 5 decocting in water for 2 hours to obtain decoction, filtering with 4 layers of gauze, and concentrating to obtain 2.0ml liquid medicine for later use.

Example 2

preparing raw materials: 25g of walnut leaves, 16g of patrinia, 18g of herba hyperici japonici, 10g of mint, 17g of camphor and 14g of angelica dahurica, and the total amount is 100 g; mixing the raw materials in a mass ratio of 1: 5 decocting in water for 2 hours to obtain decoction, filtering with 4 layers of gauze, and concentrating to obtain 2.0ml liquid medicine for later use.

Example 3

preparing raw materials: 23g of walnut leaves, 14g of herba patriniae, 19g of herba hyperici japonici, 9g of mint, 16g of camphor and 14g of radix angelicae, and the total weight is 95 g; mixing the raw materials in a mass ratio of 1: 5 decocting in water for 2 hours to obtain decoction, filtering with 4 layers of gauze, and concentrating to obtain 2.0ml liquid medicine for later use.

Example 4

preparing raw materials: 27g of walnut leaves, 17g of patrinia, 20g of herba hyperici japonici, 12g of mint, 18g of camphor and 15g of angelica dahurica, and the total amount is 109 g; mixing the raw materials in a mass ratio of 1: 5 decocting in water for 2 hours to obtain decoction, filtering with 4 layers of gauze, and concentrating to obtain 2.0ml liquid medicine for later use.

Example 5

This example provides a chemical solution, which is prepared in substantially the same manner as in example 2, except that the following raw materials are used in this example: 18g of walnut leaves, 10g of herba patriniae, 25g of herba hyperici japonici, 15g of mint, 17g of camphor and 15g of radix angelicae, and totally 100g, and finally obtaining 2.0ml of liquid medicine for later use.

Example 6

This example provides a chemical solution, which is prepared in substantially the same manner as in example 2, except that the following raw materials are used in this example: 30g of walnut leaves, 20g of patrinia, 10g of herba hyperici japonici, 8g of mint, 16g of camphor and 16g of angelica dahurica, and the total amount is 100g, and finally 2.0ml of liquid medicine is obtained for later use.

Example 7

This example provides a chemical solution, which is prepared in substantially the same manner as in example 2, except that the following raw materials are used in this example: 22g of walnut leaves, 15g of patrinia, 18g of herba hyperici japonici, 12g of mint, 18g of camphor and 15g of angelica dahurica, and the total amount is 100g, and finally 2.0ml of liquid medicine is obtained for later use.

Example 8

This example provides a chemical solution, which is prepared in substantially the same manner as in example 2, except that the following raw materials are used in this example: 27g of walnut leaves, 16g of patrinia, 20g of herba hyperici japonici, 8g of mint, 16g of camphor and 13g of angelica dahurica, and the total amount is 100g, and finally 2.0ml of liquid medicine is obtained for later use.

Example 9

This example provides a chemical solution, which is prepared in substantially the same manner as in example 2, except that the following raw materials are used in this example: 25g of walnut leaves, 20g of herba patriniae, 21g of herba hyperici japonici, 15g of mint and 19g of radix angelicae, and the total amount is 100g, and finally 2.0ml of liquid medicine is obtained for later use.

Example 10

This example provides a chemical solution, which is prepared in substantially the same manner as in example 2, except that the following raw materials are used in this example: 25g of walnut leaves, 18g of herba patriniae, 22g of herba hyperici japonici, 15g of mint and 20g of camphor, and the total amount is 100g, and finally 2.0ml of liquid medicine is obtained for later use.

Example 11

This example provides a chemical solution, which was prepared in substantially the same manner as in example 1, except that the following raw materials were used: 30g of walnut leaves, 19g of herba patriniae, 25g of herba hyperici japonici and 14g of mint, and totally 88g, and finally obtaining 2.0ml of liquid medicine for later use.

Comparative example 1

The comparative example provides a medicinal solution of 2% dipterex solution prepared from commercially available dipterex.

Comparative example 2

This comparative example provides a chemical solution, which was prepared in substantially the same manner as example 2, except that the raw materials used in this example were: herba Patriniae 26g, herba Sambuci Adnatae 20g, herba Menthae 14g, Camphora 20g, and radix Angelicae Dahuricae 20g, totally 100g, to obtain 2.0ml medicinal liquid for use.

Comparative example 3

This comparative example provides a chemical solution, which was prepared in substantially the same manner as example 2, except that the raw materials used in this example were: 30g of walnut leaves, 20g of herba patriniae, 15g of mint, 20g of camphor and 15g of angelica dahurica, and the total amount is 100g, and finally 2.0ml of liquid medicine is obtained for standby.

The effect of the drug solution of the present example was examined by a feeding test.

(1) Test method

Test pigs: 1 pig 1286 with scabies infection in pig farm is selected.

Sick pigs were randomly divided into 15 groups: group 1, 90 in total, the affected part skin was rubbed with the liquid medicine of example 1; group 2, 90 in total, the affected part skin was rubbed with the liquid medicine of example 2; group 3, 90 in total, the affected part skin was rubbed with the liquid medicine of example 3; group 4, 90 in total, the affected part skin was rubbed with the liquid medicine of example 4; the medicine liquids of application examples 5-11 are respectively smeared on the skin of the affected part, wherein the number of the groups of 5-11 is 90; each of the groups 1-11 was rubbed once more every other day after the first application, for two times; group 12, 90 heads, the medicine liquid of comparative example 1 is sprayed on the affected part skin, and only used once; the 13 th group and the 14 th group are respectively applied with 90 heads and 90 heads respectively by the liquid medicine of the comparative example 2 and the liquid medicine of the comparative example 3, and the 13 th group and the 14 th group are respectively applied with two times every other day after the first application; group 15 (placebo) consisted of 26 subjects, which were rinsed with clear water only and no drug.

All the pigs in the experiment are cleaned with clear water before taking the medicine, the scab part is slightly scraped, and the medicine is taken after the hair shaft is treated. The clinical curative effect is observed in 7 days after the administration, the curative effect is judged mainly by the parasitology examination in the test, and specifically, the number of live and dead mites of the sick pigs is randomly selected and inspected by 10 percent in the 4 th, 5 th, 6 th and 7 th tests after the administration, and the average number is taken. The counting method of the number of live and dead mites comprises the following steps: scraping skin fragments at the junction of diseased pig with a surgical scalpel, placing the fragments on a glass slide if blood is slightly seen, dripping 50% glycerol water solution, observing under a low power microscope, and counting.

(2) Criteria for determination

1. Criteria for determining sensitivity of sarcoptidosis to drugs

Each group takes 24 mites as assessment parameters, and the results are as follows:

the effect is shown: more than 80% of mites die in 7 days after the drug is applied;

the method has the following advantages: more than 60% of mites die in 7 days after the drug is applied;

and (4) invalidation: less than 60% of the mites died within 7 days after the application.

2. Criteria for therapeutic effect

And (3) healing: the scabbing and herpes of the affected part are completely disappeared, the skin recovers elasticity, fine hairs grow out initially, no itching feeling is caused, no live mites exist in microscopic examination, and the appetite is normal.

The effect is shown: the scabbing of the skin of the affected part is eliminated, no herpes is produced, the skin becomes soft, the itching shape disappears, more than 80% of mites die in microscopic examination, and the appetite is normal.

And (4) invalidation: lesions were not eliminated and less than 60% of the mites died under microscopic examination.

(3) Results

1. Examination result of mites

Table 1 shows the results of the tests of the acaricidal effect of different chemicals, from the results, the acarids have higher sensitivity to the chemicals of examples 1-11 and the chemicals of comparative example 1, the chemicals of groups 1, 2, 3 and 4, … …, 11, 13 and 14 all adopt Chinese herbal medicines, and the chemical of group 12 adopts trichlorfon, wherein the chemical of group 2 has the best effect. After the treatment of the group 2 (Chinese herbal medicine), the acarid killing rates of 4 th, 5 th, 6 th and 7 th days after the treatment are respectively 50%, 70.8%, 87.5% and 91.7%, which are respectively 16.7%, 4.1%, 8.3% and 8.4% higher than those of the group 12 (trichlorfon).

TABLE 1 results of the acaricidal effect of different chemicals

2. Results of clinical efficacy test

Clinical effects of each group were observed after 7 days of treatment, and table 2 shows the results of the treatment effects of different drug solutions on the sarcoptidosis of piglets. As can be seen from Table 2, the 1 st group to the 11 th group all show good treatment effects on the pig sarcoptidosis, the cure rate of the 2 nd group is 92.2 percent at most, which is 1.1 percent higher than that of the 12 th group which adopts trichlorfon, and no adverse reaction occurs after the 1 st group to the 11 th group are taken, so that the sick pig has a tendency of increasing appetite; although the cure rate of the trichlorfon adopted in the 12 th group is 91.1 percent, 7 sick pigs have adverse reactions such as vomit, diarrhea and the like after the trichlorfon is taken, and partial sick pigs have phenomena such as listlessness, inappetence and the like.

TABLE 2 therapeutic results of different medicinal solutions for treating sarcoptidosis

Combining the results of tables 1 and 2: the trichlorfon serving as a traditional miticide is easy to generate drug resistance after being used for a long time, so that the acaricidal rate of the Chinese herbal medicines adopted in groups 1 to 11 is slightly higher than that of the trichlorfon adopted in group 12, particularly the acaricidal rate of the group 2 is obviously higher than that of the group 12, namely the acaricidal rate of the Chinese herbal medicine in group 4d is as high as 50%, and the acaricidal rate of the trichlorfon is still 33.3%; the acaricidal rate of the Chinese herbal medicine in the 7 th day is still 8.4 percent higher than that of the trichlorfon.

Meanwhile, the cure rate of the group 1-the group 11 for treating the pig scabies by adopting the Chinese herbal medicines is not different from the cure rate of the group 12 for treating the pig scabies by adopting the trichlorfon remarkably, and the difference of the treatment effects of the Chinese herbal medicines and the trichlorfon is not remarkable according to the analysis result of variance, namely the Chinese herbal medicines can show the curative effect equivalent to that of the traditional miticide, namely the trichlorfon. Particularly, the cure rate of the group 2 adopting the Chinese herbal medicines to treat the pig sarcoptic mite is 92.2 percent, and the cure rate of the group 12 adopting the trichlorfon is 91.1 percent.

The Chinese herbal medicines are adopted for clinical medication, so that the Chinese herbal medicines are safe, low in toxic and side effects, wide in raw material source, low in cost, simple in preparation operation and wide in application prospect.

Therefore, the liquid medicine prepared from the Chinese herbal medicines in the embodiment of the application has a treatment effect on the pig sarcoptidosis, has no toxic or side effect, high safety and low cost, and is an ideal acaricidal medicine.

In summary, the external prescription for treating the pig sarcoptidosis and the preparation method thereof provided by the embodiment of the application have the advantages of good treatment effect on the pig sarcoptidosis, no toxicity, no harm, no residue, no drug resistance and low cost, and are suitable for human and livestock.

The above description is only an example of the present application and is not intended to limit the scope of the present application, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. An external prescription for treating pig sarcoptidosis is characterized by comprising the following raw materials in parts by weight: 18-30 parts of walnut leaves, 10-20 parts of patrinia, 10-25 parts of herba hyperici japonici and 5-15 parts of mint.

2. The external prescription for treating pig sarcoptidosis according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 22-27 parts of walnut leaves, 14-17 parts of patrinia, 16-20 parts of herba hyperici japonici and 8-12 parts of mint.

3. The external prescription for treating the pig sarcoptidosis as claimed in claim 1, wherein the raw materials further comprise 10-20 parts by weight of camphor.

4. The external prescription for treating pig sarcoptidosis as claimed in claim 3, wherein the raw materials further comprise 15-18 parts by weight of camphor.

5. The external prescription for treating pig sarcoptidosis according to claim 1 or 3, wherein the raw materials further comprise 10-20 parts by weight of radix angelicae.

6. The external prescription for treating pig sarcoptidosis as claimed in claim 5, wherein the raw materials further comprise 13-15 parts by weight of radix angelicae.

7. A process for the preparation of a topical formulation according to claim 1 for the treatment of pig sarcoptidosis, wherein the raw materials are decocted in water, filtered and concentrated to obtain a liquid medicine.

8. The preparation method of the external prescription for treating pig sarcoptidosis as claimed in claim 7, wherein the mass ratio of the raw materials to the water is 1: 5-10, decocting for 1-3 hours.

9. The process for the preparation of a formulation for external use according to claim 7, wherein the filtration is carried out by means of 3-5 layers of gauze.

10. The process for the preparation of a formulation for external use according to claim 7, wherein the volume ratio between before and after concentration is 100-500: 2; optionally, the liquid medicine is dried to obtain a powder.