CN1107717A

CN1107717A - Medicine for tinea

Info

Publication number: CN1107717A
Application number: CN 94102120
Authority: CN
Inventors: 刘海峰; 王克林
Original assignee: Individual
Current assignee: Individual
Priority date: 1994-03-01
Filing date: 1994-03-01
Publication date: 1995-09-06
Anticipated expiration: 2014-03-01
Also published as: CN1057449C

Abstract

The Chinese-medicinal tincture for curing 7 dermatosises including mycotic, coccus, bacillary, allergic, and nervous and cutaneous dysfunctional ones and scabies with a cure rate up to 95% and short treating course of 12 days is prepared with 11 non-toxic plant materials such as ephedra, capejasmine fruit, forsythia fruit, honeylocust thorn, siberian solomonseal rhizome, etc.

Description

Medicine for tinea

The present invention relates to a kind of dermopathic tincture that contains natural medicinal plants that is used for the treatment of.

" tinea " is a kind of dermatomycosis, because its infectiousness is strong, propagating quite extensively, thereby is a kind of common skin disease, with kind and the gradient of infection difference of fungus, can cause different clinical symptoms: as gently then pruritus, play are itched, persistent infection, then pustule appears in the part, redness, the rotten to the corn water of growing, severe patient also may concurrent lymphsystem disease.Treat the medicine of " tinea " at present, general zest is bigger, and is antipruritic slow, easily repeatedly, is difficult to cure and eradicate.Some treats dermopathic external Chinese medicine, though better therapeutic effect is arranged, because of often selecting drug toxicity for use in its prescription, as Mylabris, Semen Hydnocarpi, Fructus Crotonis, hydrargyrum etc.Because of the toxicity of face medicine is bigger, every kind of medicine all is marked with taboo or anaphylaxis, in therapeutic process, all is subjected to certain limitation, and one is careless slightly, give the patient or on every side human and environment bring new adverse consequences.

For overcoming the antipruritic slow of existing treatment skin " tinea " medicine, easily repeatedly, the shortcoming that toxicity is big.Purpose of the present invention provides a kind of antipruritic fast, and therapeutic effect is remarkable, and is nontoxic, the Chinese medicine medicine for external use of the treatment skin " tinea " that safe ready uses.

The selected prescription medicine of treatment tinea of the present invention, it has therapeutic efficiency and avirulence first-selected affirmation, puts down in writing the pharmacology and the effect of selected medicine according to relevant documents and materials:

Herba Ephedrae, warm in nature, mildly bitter flavor.Function: reach whole body internal organs meridians thoroughly.It is the day after tomorrow to stem like the meridians joint, and justice is by the heart and taste, and by the kidney and the heart, the distribution heart-yang reaches joint muscle fur outward, and the naivete that stagnates therebetween inclines to invariably, thus the hard blood stasis dispelling that can disappear, by sending out sun wind and cold, the red speckle poison of dispelling.Tinea is born in the skin table, with all medicine compatibilities, can better bring into play eliminating evil function, so tinea there is the effect of removing.Pass on from one to another, tinea is due to the pinworm, and interior YANG hyperactivity suppressing is bright, sends out fur outward, and all medicines are borrowed leading of Herba Ephedrae, to obtain interior clearly merit.

Fructus Gardeniae, flavor cold in nature if.Eight conscience, spleen (stomach), lung meridian.Function: clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Pathogenic fungus there is inhibitory action.

Fructus Forsythiae, property is flat nontoxic.Few cloudy heart channel, the medicine of fainting Yinpao (Liv 9) network gas part.All sufferings skin infection all belong to heart-fire, thus be persons particularly liable to develop skin infection 12 through panacea, double again hands, the few sun of foot, positive bright three heat through gas part of hands controlled can the bright flesh of expelling pathogenic factors from the exterior, delivers the rash addiction, and are cool in nature and rise floating.Reason soothing liver-QI gas strongly fragrant, Sheng that again can suppressing the hyperactive liver.Diuresis and antiinflammatory.The tinea scabies is controlled in sterilization.In clinical, control the tinea scabies produce effects is arranged.

Spina Gleditsiae, property is flat nontoxic, can draw all medicines and reach in the affected part, works the effect of leading the way.

Rhizoma Polygonati, sweet in the mouth is flat, nontoxic.Deceive into kidney, purple is gone into liver.Mend the solid vital qi of void of the day after tomorrow and Running water never becomes putrid, and the strong liver pathogenic factor in the exterior pinworm extremely of dispelling.For the tinea key medicine of controlling among the people, promptly be used for the treatment of ringworm, but the purple black colour of skin that easily increases the weight of of color.Especially to chickenpox type and erosive type curative effect the best of tinea pedis.

Radix Rumicis Japonici, hardship, cold nontoxic.The Radix Rumicis Crispi tincture has certain inhibitory action to multiple pathomycete.Control a bald scabies scabies, the erosion of the vulva, tinea, purple piece, tinea versicolor on the face, seborrheic dermatitis of the scalp; Control tinea, kill all worms, toxic swelling.

Radix Sophorae Flavescentis, hardship, cold nontoxic.Has disease-resistant body effect.Some common skin fungus there is in various degree inhibitory action.Heat clearing away, dampness, parasite killing.Control anal fistula, proctoptosis, skin pruritus, the mange malignant boil, erosion of vulva pruritus due to damp pathogen, scrofula is scalded.

Flos Magnoliae, property is flat nontoxic, goes into the diffusing wind heat of lung, and the sun of dispelling divides the volt fire.Lung governing skin and hair can strengthen gas and consolidating superficial resistance is eliminating evil, but Herba Ephedrae is had restrictive function.

Flos Caryophylli, acrid in the mouth, temperature, nontoxic.The sharp key of fragrance has stronger inhibitory action to fungus.Control hernia, ringworm.Little stir-fry ethanol soaks.

Fire is fragrant, fragrant sharp key, and fungus had stronger inhibitory action.

The Radix Angelicae Dahuricae, warm in nature, acrid in the mouth is little sweet.The sharp key of fragrance is gone into lung, relieving exterior syndrome, and to skin pruritus, erysipelas skin infection and fungus have significant curative effect.Clinical proof has sensible flesh effect, is the reinforcing agent of Herba Ephedrae and Spina Gleditsiae, and Herba Ephedrae is had restrictive function.

The medicine of treatment tinea of the present invention is that to select nontoxic medicinal plants prescription for use be primary raw material, through ethanol, and the tincture that the water extraction processing and fabricating forms, the composition of its primary raw material (weight) is:

Herba Ephedrae 8-14% Fructus Gardeniae 8-14%

Fructus Forsythiae 13-18% Spina Gleditsiae 3-8%

Rhizoma Polygonati 8-14% Radix Rumicis Japonici 13-18%

Radix Sophorae Flavescentis 8-14% Flos Magnoliae 8-14%

The fragrant 3-8% of Flos Caryophylli 3-8% fire

Radix Angelicae Dahuricae 3-8%

The concrete processing step of its processing and fabricating is as follows:

(1) all crude drug of above-mentioned prescription are identified and concocted, after all medicines are chosen in evaluation, concoct: Herba Ephedrae 80 parts (weight) is added 20 parts of (weight) acetic acid, and little stir-fry is to there not being steam.The Flos Magnoliae Flos Caryophylli carries out little stir-fry, and Radix Sophorae Flavescentis is mixed thoroughly with acetic acid 100ml by every Kg, in container vexed 24 hours;

(2) add 300ml ethanol by every 100g prescription raw material, soaked 10 days, then, soak with ethanol liquid is told;

(3) in the raw material after telling soak with ethanol liquid, add 300ml water, fully stir, aqueous solution is told by the former prescription raw material of every 100g;

(4) soak with ethanol liquid and the aqueous solution that (2), (3) are told respectively, and stirring placed 48 hours, made wherein that solids fully precipitates, and pressed the former prescription raw material of 100g and added 0.5g Borneolum Syntheticum, 0.5g Mentholum;

(5) filter with medicinal filter, obtain brown tincture medicinal liquid.

(6) under aseptic condition, bottle sealing.

The rapid described acetic acid of this technology is meant general tablet vinegar, wine alcohol be meant in medicinal yellow wine, used water is distilled water, also available deionized water or mineral water.

For the dark tincture medicinal liquid color that makes treatment tinea of the present invention shoals, can rise the active carbon that adds 15-20% at the dark tincture medicinal liquid of operating procedure (5).With medicinal liquid be heated to 68 °-72 ° 1 hour, decolour, be cooled to room temperature after, the elimination active carbon can obtain the transparent tincture of light brown again.

Treatment tinea tincture medicine of the present invention, the best of its primary raw material are formed (weight) and are: Herba Ephedrae 10%, Fructus Gardeniae 10%, Fructus Forsythiae 15%, Spina Gleditsiae 5%, Rhizoma Polygonati 10%, sheep tellurium 15%, Radix Sophorae Flavescentis 10%, Flos Magnoliae 10%, Flos Caryophylli 5%, fire perfume 5%, the Radix Angelicae Dahuricae 5%.

Treatment tinea tincture medicine of the present invention is used to treat dermatosis clinical observation on the therapeutic effect results such as superficial mycosis and shows: be used for the treatment of all kinds of dermatosis patients.Dermatomycosis (comprise tinea manus and pedis, tinea manuum, tinea capitis, psoriasis is stopped tinea, the glans penis god ulcer of fainting, pruritus due to damp pathogen rash) 49 examples; Coccogenous dermatopathy (flushing pimple, face blister type pimple) 7 examples; Bacilus dermatosis (lichen tuberculosis of skin) 7 examples; Allergic dermatosis (upper body urticaria, extremity urticaria, whole body urticaria) 10 examples; Dysneuria dermatoses (god's ulcer of fainting is grown water for neurodermatitis, whole body pruritus) 16 examples; Skin gland secretion obstacle dermatoses (face pimple) 9 examples, seven kinds of dermatosiss such as scabies (general) 3 examples.Administrated method: according to traditional Chinese medical science traditional therapy, in conjunction with modern medicine practice, affected part of exterior coating, be when itching and be coated with every day 2-3 time, one repeatedly.Cure back reuse medicine and consolidate a week.7-12 days time can be cured (skin lesion and subjective symptoms complete obiteration) cure rate and be reached more than 99.5%.Avirulence stimulation, no anaphylactic reaction, antibiotic wide spectrum, stronger, antipruritic rapid, safe in utilization, other hidden danger of not hiding of antibacterial power.Be used for pudendum, anus, ulcer of navel taste water, find irritated or the deterioration case, above-mentioned dermatosis is all cured in the phase of giving.Not only the curative effect at the treatment dermatomycosis is better than similar medicine, and enlarges the treatment that is used for other skin, has all obtained satisfied curative effect, welcome by the patient.

Example

Take by weighing Chinese medicine: Herba Ephedrae 10g, Fructus Gardeniae 10g, Fructus Forsythiae 15g, Spina Gleditsiae 5g, Rhizoma Polygonati 10g, sheep tellurium 15g, Radix Sophorae Flavescentis 10g, Flos Magnoliae 10g, Flos Caryophylli 5g, fiery fragrant 5g, Radix Angelicae Dahuricae 5g through accreditation.Earlier Herba Ephedrae is added 2.5g vinegar, little stir-fry is to there not being steam, Radix Sophorae Flavescentis is added 1ml vinegar in container vexed 24 hours, with Flos Magnoliae, the little stir-fry of Flos Caryophylli, then above-mentioned 11 flavor Chinese medicines being added yellow wine 300ml soaked 10 days, yellow wine solution after soaking is poured out, adding distil water 200ml again in medicine is fried stirs, and medicine is fried gone up remaining wine and wash in the distilled water, with the distilled water solution after washing with soak medicine after yellow wine mix, add 0.5g Borneolum Syntheticum and 0.5g Mentholum and stir, places 48 hours precipitations complete after, filter with filter, in brown filtrate, add the 100g active carbon, with filtrate be heated to 70 ℃ one hour, cool to room temperature filters, be filled in the bottle of 20ml and 50ml in sterilizing room, get the 250ml tincture.Sealing promptly makes the tincture that can be used for treating tinea.

Claims

1, a kind of Chinese medicine tincture is characterized in that with the non-toxic herb medicament composing prescription be primary raw material, and through ethanol, the water extraction processing and fabricating forms, and the composition of its primary raw material (weight) is:

Herba Ephedrae 8-14% Fructus Gardeniae 8-14%

Fructus Forsythiae 13-18% Spina Gleditsiae 3-8%

Rhizoma Polygonati 8-14% Radix Rumicis Japonici 13-18%

Radix Sophorae Flavescentis 8-14% Flos Magnoliae 8-14%

The fragrant 3-8% of Flos Caryophylli 3-8% fire

Radix Angelicae Dahuricae 3-8%

Medicinal yellow wine during described ethanol refers to, water refers to deionized water.

2, Chinese medicine tincture as claimed in claim 1 is characterized in that the concrete processing step of described extraction processing and fabricating is as follows:

(1) to the prescription raw material identification and the process of preparing Chinese medicine;

(2) added the 300ml soak with ethanol 10 days by every 100g prescription raw material, then, soak with ethanol liquid is told;

(3) add 200ml water by the former prescription raw material of every 100g, stir, aqueous solution is told;

(4) soak with ethanol liquid and the aqueous solution that (2), (3) are told respectively stirs evenly, and places 48 hours, and the former prescription of every 100g adds 0.5g Borneolum Syntheticum, 0.5g Mentholum;

(5) filter;

(6) under aseptic condition, bottling, sealing.

3, as claim 1,2 described Chinese medicine tinctures, it is characterized in that described processing step (4) after, can add the active carbon of 15-20%, with medicinal liquid be heated to 68 ℃-72 ℃ 1 hour, be chilled to room temperature, filter.

4, Chinese medicine tincture as claimed in claim 1 is characterized in that the best composition (weight) of described primary raw material is: Herba Ephedrae 10%, Fructus Gardeniae 10%, Fructus Forsythiae 15%, Spina Gleditsiae 5%, Rhizoma Polygonati 10%, sheep tellurium 15%, Radix Sophorae Flavescentis 10%, Flos Magnoliae 10%, Flos Caryophylli 5%, fire perfume 5%, the Radix Angelicae Dahuricae 5%.