CN1047079C - Process for preparing tinea medicine - Google Patents
Process for preparing tinea medicine Download PDFInfo
- Publication number
- CN1047079C CN1047079C CN 89103248 CN89103248A CN1047079C CN 1047079 C CN1047079 C CN 1047079C CN 89103248 CN89103248 CN 89103248 CN 89103248 A CN89103248 A CN 89103248A CN 1047079 C CN1047079 C CN 1047079C
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- Prior art keywords
- gram
- tincture
- tinea
- cortex
- radix
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to a preparation combining Chinese medicine and western medicine for treating skin diseases, such as tinea corporis, tinea imbricata, etc., which belongs to a tincture. The present invention is prepared from alcohol, water and chemical substances, and ingredients contain active carbonyl groups. In general, the product of the present invention can achieve cure by only being applied once. The present invention can kill fungi, viruses and spores and has the effects of convergence, tickle removal, heat removal and detoxification.
Description
Medicine of the present invention is a kind of dermopathic combination of Chinese and Western medicine preparations such as ulcer for the treatment of tinea corporis, tinea imbricata, tinea cruris, insect dermatitis and unknown cause; Belong to tincture.It all is the medicine that Chinese Pharmacopoeia is put down in writing that prescription constitutes.This product does not contain female, plumbous.Hydrargyrum and deleterious material.Identify the sanitary index conformance with standard by the toxicity curative effect.This product and will putting on market in large quantity.
Dermopathic pharmaceutical dosage forms such as treatment tinea corporis, tinea imbricata have tincture, powder, unguentum both at home and abroad at present.Fundamental component can be divided into several classes:
Organic acid: salicylic acid (comprising methyl salicylate, N-phenylsalicylamide), benzoic acid, undecylenic acid, glacial acetic acid etc.Salicylic mechanism has antifungic action, and skin, mucosa are had stimulation; 3-6% treats dermatomycosis, the 10-25% concentrated solution horny layer of loosening.
Phenols: phenol (carbolic acid), cresol, resorcinol (resorcin).Phenols causes protein denaturization, precipitation and endochylema permeability changes, has antibacterial and bactericidal action.
Antibiotics class: gram azoles mycin etc.
Chinese herbal medicine class: Borneolum Syntheticum, Camphora, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Pseudolaricis, Cortex Dictamni etc.
Minerals: sulfur, Lithargyrum, Calomelas, arsenicum sablimatum, hydrargyrum etc.
Hormones: prednisone, andrographolide, triamcinolone, fludrocortisone acetate etc.
Other class: dimethyl sulfoxide, iodine etc.
The medicine of being made by top composition kills strong tinea water (Guangzhou), black and white ringworm medicine (Changzhou, Wuxi), skin ringworm medicine (Guangdong), medicine for treating tinea (Jiangxi), econazole (Tianjin), kills strong tinea cream (Hubei), tinea ointment (Tianjin), fluocinonide (Tianjin), triamcinolone ointment (Hubei) etc.
Dermopathic medicines such as the treatment tinea corporis that countries in the world produce, tinea imbricata have some weak point.
1, the patient needs to put on the skin every day three times, and several days is a course of treatment.The course of disease is long, weak effect, easily recurrence.
2, dermatophytes only there is inhibitory action.
3, tincture is big to skin irritation, and the unguentum greasy feeling is strong, dirty linen; Powder uses trouble.
This invention has added formaldehyde in the mill, make to contain active carbonyl in the solution, formaldehyde can with proteinic amino the combination, changed the function of peptide chain, make protein denaturation, precipitation, can kill fungi, virus, brood cell etc.Simultaneously, compare, reduced salicylic acid, benzoic acid consumption, increased by one group of heat clearing and damp drying in the prescription again with medicine of the same race, the antipruritic tinea of going out, the parasite killing granulation promoting, the Chinese medicine of skin ulcer is treated in detoxifcation.
The medicine of manufacturing of the present invention has three advantages:
1, these product are only put on the skin once, just can fully recover, and short treating period, usage is simple, has changed traditional medicine for external use and has put on the skin three times every day, and several days is the method for a course of treatment.
2, these product can not only be antibacterial, and the energy kill fungi, virus, brood cell, and it is antipruritic to have the Chinese medicine convergence again concurrently, the effect of heat-clearing and toxic substances removing.
3, this product zest is little, and clean hygiene is nontoxic to human body, does not contain harmful substances such as female, plumbous, hydrargyrum.
Embodiment:
The raw material of getting all the ready before the manufacturing with the cubage of every 10000ML medicinal liquid is:
Cortex Phellodendri 100-500 gram Rhizoma Paridis 100-500 gram
Radix Sophorae Flavescentis 100-500 gram Radix Trichosanthis 50-300 gram
Cortex Pseudolaricis 100-500 gram salicylic acid 50-500 gram
Fructus Cnidii 50-300 gram benzoic acid 100-1000 gram
Cortex Dictamni 60-300 gram Camphora 50-300 gram
Rhizoma Atractylodis 50-300 gram formaldehyde 50ml-800ml
Radix Angelicae Dahuricae 100-600 gram 50-85% ethanol 10000-16000ml
Fructus Kochiae 50-200 gram essence is an amount of
Operating process:
1, the ethanol of preparation dilute concentration;
2, Chinese medicine is packed in certain container, soak ten flavor Chinese medicines 3-30 days or longer time, extract active ingredient with infusion process with Diluted Alcohol.Make tincture, also can divide secondary or extract wherein composition three times, reach the consumption of regulation after the mixing.
3, salicylic acid, benzoic acid, Camphora are added and contains in the tincture of Chinese medicinal ingredients, make dissolving.
4, add formaldehyde, stirring again.
5, add essence to correct abnormal smells from the patient promptly.
Claims (1)
1, the tincture preparation method of a kind of treatment tinea corporis that contains active carbonyl, tinea imbricata, tinea cruris is characterized in that it comprises the following steps:
(1) get the raw materials ready by following consumption:
Cortex Phellodendri 100-500 gram, flea woods 100-500 gram, Radix Sophorae Flavescentis 100-500 gram, Radix Trichosanthis 50-300 gram, Cortex Pseudolaricis 100-500 gram, Fructus Cnidii 50-300 gram, Cortex Dictamni 50-300 gram, Rhizoma Atractylodis 50-300 gram, Radix Angelicae Dahuricae 100-600 gram, Fructus Kochiae 50-200 gram, salicylic acid 50-500 gram, benzoic acid 100-1000 gram, Camphora 50-300 gram, formaldehyde 50-800ml;
(2) Diluted Alcohol of preparation 50-85%;
(3) use the Diluted Alcohol of the 50-85% of 10000-16000ml that above-mentioned Cortex Phellodendri, Rhizoma Paridis, Radix Sophorae Flavescentis, Radix Trichosanthis, Cortex Pseudolaricis, Fructus Cnidii, Cortex Dictamni, Rhizoma Atractylodis, the Radix Angelicae Dahuricae, the Fructus Kochiae ten flavor Chinese crude drugs were soaked 3-30 days, make the tincture that contains middle pharmaceutically active ingredient with infusion process;
(4) salicylic acid, benzoic acid and Camphora are added the prepared tincture of step (3), make dissolving;
(5) add formaldehyde again, stir;
(6) add the described tincture that an amount of essence promptly gets 10000ml.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 89103248 CN1047079C (en) | 1989-05-13 | 1989-05-13 | Process for preparing tinea medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 89103248 CN1047079C (en) | 1989-05-13 | 1989-05-13 | Process for preparing tinea medicine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1047205A CN1047205A (en) | 1990-11-28 |
| CN1047079C true CN1047079C (en) | 1999-12-08 |
Family
ID=4855046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 89103248 Expired - Fee Related CN1047079C (en) | 1989-05-13 | 1989-05-13 | Process for preparing tinea medicine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1047079C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1057449C (en) * | 1994-03-01 | 2000-10-18 | 刘海峰 | Medicine for tinea |
| CN102688429B (en) * | 2012-06-08 | 2013-11-27 | 王建国 | Medicinal tincture for treating fungal diseases |
| CN103070960B (en) * | 2013-02-01 | 2014-07-09 | 吉林农业大学 | External medicine linimentum for treating equus mange and preparation method of external medicine linimentum |
-
1989
- 1989-05-13 CN CN 89103248 patent/CN1047079C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1047205A (en) | 1990-11-28 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C15 | Extension of patent right duration from 15 to 20 years for appl. with date before 31.12.1992 and still valid on 11.12.2001 (patent law change 1993) | ||
| OR01 | Other related matters | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |