CN101433619B

CN101433619B - Tinctura for eliminating tinea and relieving itching

Info

Publication number: CN101433619B
Application number: CN2008101476166A
Authority: CN
Inventors: 王洪斌
Original assignee: Individual
Current assignee: Individual
Priority date: 2008-11-20
Filing date: 2008-11-20
Publication date: 2011-06-15
Anticipated expiration: 2028-11-20
Also published as: CN101433619A

Abstract

The invention discloses a tincture against tinea and itching. More than fifteen kinds of medicaments such as cortex phellodendri, indigo, rhubarb, pericarpium zanthoxyli, clove, peach kernel, pomegranate bark, Chinese gall are reasonably mixed and then subjected to crushing, extraction and separation, preparation, filtering, measuring and product finishing to obtain the tincture against tinea and itching. The tincture against tinea and itching is a transparent external use liquid preparation which has the smell of beetle fart and is brown yellow, and has obvious effects of treating chronic skin diseases such as neurodermitis, psoriasis, chronic eczema, lichen, ringworm of the foot, intractable prurigo, verruca acuminata, skin hyperkeratosis.

Description

Tinctura for eliminating tinea and relieving itching

Technical field

The present invention relates to a kind of topical agent for the treatment of multiple chronic dermatosis.Be specifically related to a kind of tinctura for eliminating tinea and relieving itching.

Background technology

Chronic dermatosis such as neurodermatitis, psoriasis, chronic eczema, tinea manus and pedis (the mashed bifurcation that refers to), lichen, viral condyloma latum, skin and follicular keratosis, ill crowd is more, adopt hormone, antibiotic, antianaphylactic treatment clinically, how based on controlling symptoms, certain curative effect is arranged, but cure rate is not high.Particularly psoriasis, the lichen patient of long, the skin lesion area big (the skin lesion area can reach body surface area more than 80%) of medical history, many doctors feel simply helpless, and studying carefully its main cause and being does not have suitable available, topical agent that good effect is easy to use.

Summary of the invention

The purpose of this invention is to provide the multiple chronic dermatosis of a kind of suitable treatment, and general hair style patient's external tinctura for eliminating tinea and relieving itching easy to use, that the skin absorption affinity can solve the large tracts of land skin lesion by force, especially.The sclerosis that promptly takes place to the outer wiping of condyloma acuminatum reflects cure rate and radical rate height.

Tinctura for eliminating tinea and relieving itching of the present invention is made by following raw materials in weight portion:

Cortex Phellodendri 15～25 Indigo Naturaliss 10～20 Radix Et Rhizoma Rhei 10～20 Fructus Zanthoxylis 5～15 Flos Caryophyllis 5～15

Semen Persicae 5～15 Pericarpium Granatis 5～15 Galla Chinensiss 5～25 Fructus Evodiaes 5～15 Fructus Psoraleaes 5～15

The Radix Paeoniae Alba 5～15 Fructus Kochiae 5～15 Radixs Polygoni Multiflori 5～15 Borneolum Syntheticums 5～15 Alumens 5～10

75% ethanol: 1000～2000.

Tinctura for eliminating tinea and relieving itching of the present invention is made by following optimum weight part proportion raw material:

Cortex Phellodendri 15 Indigo Naturaliss 15 Radix Et Rhizoma Rhei 15 Fructus Zanthoxylis 10 Flos Caryophyllis 10

Semen Persicae 10 Pericarpium Granatis 10 Galla Chinensiss 15 Fructus Evodiaes 10 Fructus Psoraleaes 10

The Radix Paeoniae Alba 10 Fructus Kochiae 10 Radixs Polygoni Multiflori 10 Borneolum Syntheticums 5 Alumens 5

75% ethanol: 1500.

The making step of tinctura for eliminating tinea and relieving itching of the present invention is as follows:

(1) pulverizes: get Cortex Phellodendri, Indigo Naturalis, Radix Et Rhizoma Rhei, Fructus Zanthoxyli, Flos Caryophylli, Semen Persicae, Pericarpium Granati, Galla Chinensis, Fructus Evodiae, Fructus Psoraleae, the Radix Paeoniae Alba, Fructus Kochiae fleece-flower root by the described prescription proportioning of claim 1 and pulverize;

(2) extraction separation: the Chinese drugs powder after will pulverizing adds 75% alcohol solvent by the prescription proportioning, after fully stirring, leaves standstill more than 72 hours, and stir 2-3 every day, uses four layers of filtered through gauze then.Get its filtrate for later use;

(3) measure: mother-in-law Mei Shi specific density table is measured proportion (check on the quality, survey drug level);

(4) allotment: Borneolum Syntheticum, the allotment of Alumen powder;

(5) filter: analytical paper filters, and produces in batches and filters with filter cloth;

(6) measure: mother-in-law Mei Shi specific density table is measured proportion (check on the quality and measure drug level) 5-6 degree, 1.04.

(7) finished product: getting and measuring the standard compliant filling liquid in back is the 30ml/ bottle, adds a cover the back and is finished product; Be illustrated as commodity after labelled.

The present invention is a brown yellow transparent liquid, has beetle wind stink, contains compositions such as biological glycoside, alkali, ketone, steroid, phenol, gallic acid, tannic acid.Its function is: sterilizing and itch-relieving, dissolve cutin, peel off pathological tissues; Remove squama keratinization, pimple, erythema, make pathological tissues lose activity, incrustation comes off.Mechanism is: 1.. the local oxidation reaction that takes place.Changes such as pathological changes pimple speckle generation peony, brownish red, brownish black, effects such as sterilizing and itch-relieving, antiinflammatory (normal skin does not react).2.. peel off pathological tissues.Sick cell is lost vigor, and downright bad gradually, dry, local incrustation is squama, bulk, large stretch of sample and comes off.Reach squama, keratinization, pimple, the speckle effect of removing.3.. ooze Pi Xingqiang.Under carrier function, the penetration power that medicine infiltrates Intradermal is stronger, gives full play to the focus effect of removing.4.. the paralysis teleneuron reaches itching-relieving action.Be applied to outward (repeatedly several times) on strange prurigo papule, the speckle, a few minutes can be antipruritic.As auxiliary with infrared lamp, TDP lamp, electric heater or hair dryer, make telangiectasis, strengthen drug osmotic, antipruritic effect is better, and the antipruritic time is longer.5.. peel off the diseased region pigment, promote skin repair.

Therapeutic Method: among a small circle or being dispersed in property skin lesion pathological changes,, dip in swab and to get medicament of the present invention and put the part outward on the skin as pimple, pruritus.The more person of extent of disease puts it outward on the skin with instruments such as mosquito forceps men cotton ball, and is fully moistening, is good with slime flux not.Put on the skin 3-4 time every day outward.The person of having ready conditions can use infrared lamp, TDP lamp, electric heater or hair dryer at local heat 50-60 ℃, and curative effect is better.Extent of disease less (pimple, speckle are the distribution of being dispersed in property, the skin lesion gross area is little) person needs continuous use＞7 day, treat that the pathological changes cutin comes off after, consolidated again 2-3 days.Extent of disease accounts for body surface area, continuous use＞15 day.General sexually transmitted disease (STD) people, the skin lesion area reaches more than 1/2 or 2/3, should burst under the physician guidance at times outside liniment for treatment, continuous use＞25 day.Red and swollen obviously person, particularly Folium Styracis Suberifoliae type patient should control inflammation combined treatments such as endo-medicine.The high person of blood glucose answers blood sugar control.The condyloma acuminatum patient dips in medicine with toothpick or cotton swab and is applied to the wart body, and repeatedly several times, diameter falls being coated with the limit less than 0.2cm with bottom; The sclerosis reflection takes place in big person immediately, comes off in 5-7 days; The prolonged illness patient, the local organization hypertrophy has the piece sense, and medication is coated with 1-2 days outward, and every day 1-2 time, differential hardening comes off.Do not hinder normal structure, preventing from scar, the skin rehabilitation is normally as before.

Case is as follows:

(1) neurodermatitis

Relax certain, the man, 25 years old, went to a doctor in February, 2007.Collare has obviously and scratches surplus the red speckle pimple ten in both sides.Readme is itched night, grabs and his like yellow fluid when itching very, and ill 5 years surplus, has been several institutes large hospital and has all cured, and sx is gone to a doctor in the recent period.Take voluntarily outer putting on the skin home with topical agent of the present invention, utilize local clinic TDP lamp heating every day 1 time every day 3 times, continuous 25 days, cure.Follow up a case by regular visits to not recurrence in January, 2008.

(2) general property psoriasis

Lee, the man, 40 years old, on July 7th, 2007 went to a doctor.From the both feet back ofs the body begin to go up before shin, knee joint is to thigh, extremely big midleg behind the both legs, buttocks, waist both sides are to back median line both sides, umbilicus edge and upper abdomen, near place such as the upper limb both hands wrist, red mound speckle, silvery white squama, especially with both legs, lower back for very, surplus the medical history ten year, readme is gone to a doctor not have to several large hospitals and is taken a turn for the better.Adopt topical agent of the present invention, dip in cotton ball and look into the part, heat piecewise with the TDP lamp simultaneously, the disappearance of itching is thereafter itched in local play during heating.Heat every day 1 time, the band medicine is gone home, outer voluntarily the putting on the skin 2 times of being in, and continuous use is after 3 days, and squama begins to come off, and pathological tissues is the brownish black reaction.To the 10th day, a large amount of squamas, pimple, speckle partly disappeared, and pathological tissues comes off, very end flushing.Continuous external treatment to 25 day, erythema, pimple, squama disappear, and the skin major part often is become a full member, and the patient is with the medicine after treatment 30 days of going home, healing.It is normal that skin recovers, and the diseased region pigment disappears.

(3) general property mixed type lichen

Thank certain, the man, 26 years old, JIUYUE was gone to a doctor on the 17th in 2008.Back of the body right side scapula is to shoulder, clavicle upper limb, armpit skin; Back of the body middle part to buttocks, again to both legs to ankle joint skin; The front upper abdomen is to perineal position, and again to instep skin, popularity lichen sample changes thigh to the shin.The take on a red color inflammation performance of upper abdomen, the back of the body, scapula affected skin edge, surplus skin purple; Pudendum, femoribus internus speckle are intensive, and the reorganization of skin generation atrophy sample exceeds normal skin, and affected skin is covered with pimple, very itches, and is coated with white squama, and inflammation is obvious, and netted stricture of vagina is arranged.Do not become the skin generation popularity dyskeratosis follicularis of purple.This patient except that cervical region face and skin of head normally, reorganization has all taken place in all the other skins, affected skin accounts for more than 90% of body surface area.Patient's readme morbidity summer in 2003, many all the more more, used many medicines invalid.There are 4 medical practitioners also to feel simply helpless in the family.All answer and to treat to the various big hospital prescription on individual diagnosis.In this year JIUYUE see a doctor.Adopt medicament of the present invention, the operational approach psoriasis of ruling together.Because skin lesion is extensive, divides three three period external treatment.Control earlier more than the waist, inferior to below knee, be the outside in buttocks, pudendum, the thigh at last.A few minutes behind the medicine for external application, the brownish black reaction takes place, the heavy more position of pathological changes, reaction color is dark more, dense more.During the medication, affected skin repeatedly is block sheet and comes off behind medial leg, the thigh, and abdominal part, back pimple, buttocks squama are peeled off gradually.After the medication 24 days, slit atropurpureus skin, pimple, speckle of former purple disappears 2/3, and it is smooth that skin shows, and back, abdominal part pigment disappear comparatively fast, the patient is with the medicine outer voluntarily liniment for treatment of going home, check after 15 days, back, epigastrium 2/3 skin are often become a full member, and skin recovers normal below knee, outside skin is brownish black in shank, pudendum, the thigh, also have a small amount of speckle, the existing after treatment of being in is voluntarily estimated to cure about first quarter moon.During the treatment, no New Development inflammation, pimple and speckle.

(4) chronic eczema

Chen, the woman, 31 years old, went to a doctor in June, 2006, and two upper limb and the back of the hand, finger are dispersed in pimple, and the right hand is carried on the back erythema in the form of sheets, exceeds skin, and readme is very itched, and does not have improvement to other hospital treatments, medical history 5 years.Put on the skin outward with pharmaceutical dosage form of the present invention, antipruritic fast, medication to 3 day, red macule is dwindled, complexion changed is light, accompanies a little squama to come off, and continues the medication first quarter moon, and skin lesion disappears 2/3rds, continuous use recovery from illness in 26 days.

(5) amyloid pathological changes

Zhang, the man, 63 years old, the retired worker, JIUYUE was gone to a doctor on the 23rd in 2006.Two lower limb cover with intensive pimple, are excipuliform, loam cake white powder sample thing, and skin is pale brown color, unplugs the powder that is white in color in the pimple with pin.Readme medical history 25 years was sought medical advice many hospitals to no effect, and long gradually many, itch.Adopt pharmaceutical dosage form of the present invention to put on the skin outward, itching promptly disappears, and begins desquamation next day, medication to the 7 days, and the pathological changes macule comes off in the form of sheets, and is normal to skin rehabilitation in 20 days.

The specific embodiment

The present invention is made by following raw materials in weight portion:

The Radix Paeoniae Alba 10 Fructus Kochiae 10 Radixs Polygoni Multiflori 10 Borneolum Syntheticums 10 Alumens 5

75% ethanol 1500.

The present invention makes by following making step:

(2) extraction separation: the Chinese drugs powder after will pulverizing adds 75% alcohol solvent by the prescription proportioning, after fully stirring, leaves standstill more than 72 hours, and stir 2-3 every day, uses four layers of filtered through gauze then, gets its filtrate for later use;

(3) measure: mother-in-law Mei Shi specific density table is measured proportion and is checked on the quality, and surveys drug level;

(4) allotment: Borneolum Syntheticum, the allotment of Alumen powder;

(6) measure: mother-in-law Mei Shi specific density table is measured proportion (check on the quality and measure drug level) 5-6 degree, 1.04;

(7) finished product: getting and measuring the standard compliant filling liquid in back is the 30ml/ bottle, adds a cover the back and is finished product; Be illustrated as commodity behind the last label.

Claims

1. tinctura for eliminating tinea and relieving itching is characterized in that being made by following raw materials in weight portion:

The Radix Paeoniae Alba 5～15 Fructus Kochiae 5～15 Radixs Polygoni Multiflori 5～15 Borneolum Syntheticums 5～10 Alumens 5～10

75% ethanol 1000～2000.

2. according to claim 1 tinctura for eliminating tinea and relieving itching, it is characterized in that making by following optimum weight part proportion raw material:

75% ethanol: 1500.

3. the method for preparing tinctura for eliminating tinea and relieving itching as claimed in claim 1 is characterized in that preparation process is as follows:

(3) measure: mother-in-law Mei Shi specific density table is measured proportion;

(4) allotment: Borneolum Syntheticum, the allotment of Alumen powder;

(6) measure: mother-in-law Mei Shi specific density table is measured proportion, 5-6 degree, 1.04;