CN110754593A - Spleen-tonifying and stomach-nourishing rice-containing dilute beverage and preparation method thereof - Google Patents

Spleen-tonifying and stomach-nourishing rice-containing dilute beverage and preparation method thereof Download PDF

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Publication number
CN110754593A
CN110754593A CN201911212833.3A CN201911212833A CN110754593A CN 110754593 A CN110754593 A CN 110754593A CN 201911212833 A CN201911212833 A CN 201911212833A CN 110754593 A CN110754593 A CN 110754593A
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parts
rice
spleen
stomach
tonifying
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Inventor
钟虹光
尧梅香
黄红卫
周明
朱晓娟
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Jiangxi Gongqing Jiangzhong Dietotherapy Technology Co Ltd
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Jiangxi Gongqing Jiangzhong Dietotherapy Technology Co Ltd
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Priority to CN201911212833.3A priority Critical patent/CN110754593A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/02Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
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    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
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    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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Abstract

The invention discloses a spleen-tonifying and stomach-nourishing rice dilute beverage which comprises, by weight, 2-5 parts of ginseng, 8-20 parts of poria cocos, 5-10 parts of Chinese yam, 5-10 parts of lotus seeds, 1-5 parts of fructus amomi, 9-20 parts of white hyacinth beans, 9-20 parts of semen coicis, 2-5 parts of orange peel, 2-5 parts of platycodon grandiflorum and 2-5 parts of liquorice, and further comprises 80-150 parts of rice, 20-30 parts of wheat, 1-4 parts of a grain stabilizer, 0-10 parts of a sweetening agent and 0-10 parts of a seasoning substance. The invention has the beneficial effects that: the rice milk beverage has the advantages of definite curative effect on spleen and stomach weakness, safe use and positive and obvious treatment effect on patients with the spleen and stomach weakness symptoms of clinical manifestations such as chronic gastritis, gastric and duodenal ulcers, gastroptosis, chronic diarrhea, functional dyspepsia, ulcerative colitis and the like, abdominal pain, abdominal distending pain, inappetence, anorexia, loose stool, nausea, vomiting, tiredness, hypodynamia, tiredness, laziness, speaking and the like.

Description

Spleen-tonifying and stomach-nourishing rice-containing dilute beverage and preparation method thereof
Technical Field
The invention relates to the field of food processing, and particularly relates to a spleen-tonifying and stomach-nourishing rice milk beverage and a preparation method thereof.
Background
The rice beverage is a semi-solid substance with certain viscosity and consistency, and is prepared from various grains by mechanically pulverizing, decocting in water, and gelatinizing. The grains used for making the rice-flour gruel include rice, black rice and purple rice, and the coarse cereals include millet, corn, sorghum, wheat, barley, oat, etc. The rice paste can be digested and absorbed by human body rapidly, the fragrance of grains is fully released, the sensory enjoyment is enhanced, the appetite is promoted, and meanwhile, energy can be provided for the body rapidly.
Patent literature discloses a preparation method of compound health-care rice paste (CN201510164536.1), which comprises the following steps: the rice paste is prepared from germinated Oryza Glutinosa, germinated brown rice, germinated semen glycines, fructus Lycii, and sugar. Through the implementation of the invention, the glutinous rice, the brown rice and the soybeans are induced to germinate, and the germinated glutinous rice, the brown rice and the soybeans not only retain the original nutrition, but also have significant changes in the nutritional components. The germinated glutinous rice, the germinated brown rice, the germinated soybean and the medlar are combined to prepare the rice paste, the formed rice paste has richer nutrition and more obvious health care effect on the premise of not increasing the cost, the common rice paste is greatly increased in value, and the rice paste becomes a rice paste product with characteristics and high quality. In addition, the prepared rice paste has low cost and good taste, is widely suitable for various crowds to eat, can be used as a leisure food, and also can be used as a staple food, so that people can be kept healthy in the conventional diet process. The product of the invention has very special characteristics and very good market prospect. Although the rice paste product of the invention is wide in audience and has the health care function, the rice paste product does not have the functions of tonifying spleen and nourishing stomach.
Chinese patent library discloses a coarse grain rice paste and a preparation method 0201410526754.0 thereof, wherein the coarse grain rice paste is prepared from the following components in parts by weight: 60-80 parts of polished round-grained rice, 30-50 parts of oat, 30-50 parts of corn, 20-30 parts of black rice, 20-30 parts of purple rice, 15-20 parts of red bean, 15-20 parts of sweet potato, 5-10 parts of apple, 5-10 parts of Chinese date, 5-10 parts of lotus seed and 5-10 parts of peanut kernel. The coarse grain rice paste and the preparation method thereof are rich in nutrition, contain more dietary fibers, can effectively reduce cholesterol in a human body, and have the effects of reducing blood sugar, reducing blood fat, relieving fatigue and the like; in addition, different soaking processes are adopted according to different coarse grains, so that the hardness of the coarse grains is improved, and the mouthfeel of the coarse grains is improved. However, the rice paste product is completely made of coarse grains, and does not have the health-care function of tonifying spleen and nourishing stomach.
The patent application with the publication number of CN104825962A discloses a Chinese patent medicine preparation for treating the dysfunction of transportation and transformation of the spleen and the stomach and a preparation method thereof, and the Chinese patent medicine preparation for treating the dysfunction of transportation and transformation of the spleen and the stomach comprises the following raw materials in percentage by weight: 12 to 15 percent of ginseng, 12 to 15 percent of tuckahoe, 10 to 15 percent of fried hawthorn, 10 to 15 percent of yam, 7 to 10 percent of fried white hyacinth bean, 3 to 6 percent of lotus seed, 5 to 8 percent of fried coix seed, 3 to 6 percent of fructus amomi, 4 to 7 percent of seville orange flower and 12 to 15 percent of honey-fried licorice root, aiming at solving the technical problem of providing a Chinese patent medicine preparation tablet and paste for treating the dysfunction of transportation and transformation of the spleen and the stomach, which have the functions of tonifying the spleen and the stomach and benefiting the lung qi, and are used for treating weakness of the spleen and the stomach, anorexia and defecation peaceful, short breath, cough, acratia, serious illness and physical strength. The product of the invention is composed of medicinal materials, and prepared into Chinese patent medicine preparation tablets and paste, has poor taste and less audiences, and is difficult to adapt to popular consumer groups.
As can be seen from the above, no rice beverage with the functions of tonifying spleen and nourishing stomach exists in the existing market.
Disclosure of Invention
In order to overcome the defect that the rice dilute beverage product in the prior art does not have the functions of strengthening the spleen and nourishing the stomach, the invention provides the rice dilute beverage for strengthening the spleen and nourishing the stomach and the preparation method thereof, and the rice dilute beverage is realized by the following technical scheme.
The spleen-tonifying and stomach-nourishing rice drink comprises, by weight, 2-5 parts of ginseng, 8-20 parts of poria cocos, 5-10 parts of Chinese yam, 5-10 parts of lotus seeds, 1-5 parts of fructus amomi, 9-20 parts of white hyacinth beans, 9-20 parts of semen coicis, 2-5 parts of orange peel, 2-5 parts of platycodon grandiflorum and 2-5 parts of liquorice, and further comprises 80-150 parts of rice, 20-30 parts of wheat, 1-4 parts of a grain stabilizer, 0-10 parts of a sweetening agent and 0-10 parts of a seasoning substance.
Further, the grain stabilizer comprises 1-2 parts of monoglyceride, 0-1 part of cellulose and 0-1 part of sodium carboxymethyl cellulose.
Further, the rice is one of polished round-grained rice, long-grained rice, glutinous rice, millet and black rice; the wheat is one of wheat, barley, oat, quinoa and highland barley.
Further, the seasoning composition also comprises 0.1-2 parts of a sweetening agent and 0.1-10 parts of a seasoning substance.
Further, the sweetener is one or more of white granulated sugar, brown sugar, sucralose and stevioside.
Further, the flavoring substance is milk powder and/or essence.
A preparation method of a spleen-tonifying and stomach-nourishing rice porridge beverage comprises the following steps: s1, weighing 2-5 parts of ginseng, 8-20 parts of poria cocos, 5-10 parts of Chinese yam, 5-10 parts of lotus seed, 1-5 parts of fructus amomi, 9-20 parts of white hyacinth bean, 9-20 parts of semen coicis, 2-5 parts of orange peel, 2-5 parts of platycodon grandiflorum, 2-5 parts of liquorice, 80-150 parts of rice and 20-30 parts of wheat, respectively performing immersion washing to remove impurities; s2, respectively crushing ginseng, Chinese yam, lotus seeds, fructus amomi, white hyacinth beans and coix seeds, sieving the crushed materials with a 80-mesh sieve, and respectively extracting and concentrating the sieved materials to obtain the ginseng, Chinese yam, lotus seeds, fructus amomi, white hyacinth beans and coix seeds with the concentration ratio of 1: 1, a concentrated solution; respectively crushing poria cocos, platycodon grandiflorum, liquorice and orange peel, extracting twice, combining extracting solutions obtained after twice extraction, and concentrating to obtain a concentrate with a concentration ratio of 1: 1, a concentrated solution; s3, mixing 80-150 parts of rice, 20-30 parts of wheat and 1-4 parts of a grain stabilizer, finely grinding, mixing 2-5 parts of a ginseng concentrated solution, 8-20 parts of a poria cocos concentrated solution, 5-10 parts of a Chinese yam concentrated solution, 5-10 parts of a lotus seed concentrated solution, 1-5 parts of a fructus amomi concentrated solution, 9-20 parts of a white hyacinth bean concentrated solution, 9-20 parts of a semen coicis concentrated solution, 2-5 parts of an orange peel concentrated solution, 2-5 parts of a platycodon grandiflorum concentrated solution and 2-5 parts of a liquorice concentrated solution, adding water, uniformly mixing, and finely grinding to obtain a mixed solution; s4, emulsifying and homogenizing the mixed solution by using a homogenizer, and then pre-gelatinizing by using a gelatinizing device to obtain a cured mixture; s5, crushing the cooled cured mixture by using a high-pressure homogenizer to obtain a gelatinized and crushed mixture; and S6, carrying out ultrahigh-temperature instantaneous sterilization on the gelatinized and crushed mixture, and carrying out low-temperature aseptic filling to obtain the spleen-tonifying and stomach-nourishing rice dilute beverage.
Further, in S2, extracting the raw materials of tuckahoe, platycodon grandiflorum, liquorice and orange peel twice, wherein the first extraction time is 120min, and the extraction temperature is 100 ℃; the second extraction time is 90min, and the extraction temperature is 100 deg.C.
Further, in S3, the slurry Baume degree of the mixed liquid is 6 to 23.
Further, in S6, the temperature adopted for ultrahigh temperature instantaneous sterilization is 135-180 ℃ and the time is 5-10S.
The invention has the beneficial effects that: the rice milk beverage has the advantages of definite curative effect on spleen and stomach weakness, safe use and positive and obvious treatment effect on patients with the spleen and stomach weakness symptoms of clinical manifestations such as chronic gastritis, gastric and duodenal ulcers, gastroptosis, chronic diarrhea, functional dyspepsia, ulcerative colitis and the like, abdominal pain, abdominal distending pain, inappetence, anorexia, loose stool, nausea, vomiting, tiredness, hypodynamia, tiredness, laziness, speaking and the like.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
First embodiment
(1) Weighing the following components in parts by weight: 3 parts of ginseng, 20 parts of poria cocos, 10 parts of Chinese yam, 10 parts of lotus seed, 1 part of fructus amomi, 20 parts of white hyacinth bean, 20 parts of semen coicis, 3 parts of orange peel, 3 parts of platycodon grandiflorum, 2 parts of liquorice, 150 parts of polished round-grained rice, 25 parts of oat, 2 parts of monoglyceride, 1 part of cellulose and 1 part of sodium carboxymethylcellulose, and the raw materials are respectively soaked and washed to remove impurities;
(2) in the raw materials, ginseng, tuckahoe, yam, lotus seed, amomum fruit, white hyacinth bean, coix seed, orange peel, platycodon root and liquorice belong to the traditional Chinese medicine composition, the raw materials of the traditional Chinese medicines are respectively crushed, pass through a 80-mesh screen, and then are extracted by normal pressure water, the extraction concentration ratio is 1: 1, a concentrated solution; extracting Poria, radix Platycodi, Glycyrrhrizae radix, and pericarpium Citri Tangerinae respectively twice, the first extraction time is 120min, the extraction temperature is 100 deg.C, the second extraction time is 90min, the extraction temperature is 100 deg.C, and the two extractive solutions are combined and concentrated to obtain a Chinese medicinal composition with a concentration ratio of 1: 1 in the form of a concentrate.
(3) 150 parts of polished round-grained rice, 25 parts of oat, 2 parts of monoglyceride, 1 part of cellulose and 1 part of sodium carboxymethylcellulose are mixed and finely ground, then an important composition in a corresponding weight ratio is added, water is added for uniformly mixing, the baume degree of the slurry is 6-23, and then the mixed slurry is finely ground to obtain a mixed solution.
(4) Emulsifying and homogenizing the mixed solution by using a homogenizer, and then pre-gelatinizing for 30min by using a gelatinizing device to obtain a cured mixture;
(5) crushing the cooled cured mixture by using a high-pressure homogenizer to obtain a gelatinized and crushed mixture;
(6) and carrying out ultrahigh-temperature instantaneous sterilization on the gelatinized and crushed mixture and carrying out low-temperature aseptic filling to obtain the spleen-tonifying and stomach-nourishing rice-containing diluted beverage.
Second embodiment
Weighing the following components in parts by weight: 2 parts of ginseng, 20 parts of tuckahoe, 8 parts of yam, 8 parts of lotus seed, 5 parts of fructus amomi, 10 parts of white hyacinth bean, 20 parts of semen coicis, 3 parts of orange peel, 3 parts of platycodon grandiflorum, 2 parts of liquorice, 5 parts of white granulated sugar, 80 parts of japonica rice, 30 parts of oat, 2 parts of monoglyceride, 0 part of cellulose, 1 part of sodium carboxymethylcellulose and 5 parts of white granulated sugar. The remaining steps are different from the first embodiment in that the grain stabilizer of the second embodiment mainly contains no cellulose and the composition of other main raw materials, as compared with the first embodiment.
Third embodiment
Weighing the following components in parts by weight: 3 parts of ginseng, 20 parts of tuckahoe, 10 parts of yam, 10 parts of lotus seed, 1 part of fructus amomi, 20 parts of white hyacinth bean, 20 parts of semen coicis, 3 parts of orange peel, 3 parts of platycodon grandiflorum, 2 parts of liquorice, 1 part of sucralose, 150 parts of japonica rice, 25 parts of oat, 1 part of monoglyceride, 1 part of cellulose, 1 part of sodium carboxymethylcellulose, 5 parts of white granulated sugar and 1 part of sucralose, and the raw materials are respectively soaked and washed to remove impurities. The remaining steps are the same as in the first embodiment.
The third embodiment differs from the first embodiment mainly in that the parts of monoglyceride are one part, and a sweetener is added.
The spleen-tonifying and stomach-nourishing rice milk beverage disclosed by the invention has the effects of nourishing the stomach, simultaneously regulating the spleen and related viscera, more mainly taking the principal and secondary aspects into consideration, enhancing the disease resistance of an organism by enhancing the immunity of a gastrointestinal digestive system, and having positive and obvious treatment effects on the symptoms of weakness of the spleen and the stomach, such as abdominal pain, abdominal distending pain, inappetence, loose stool, nausea and vomiting, warming qi, fatigue and weakness and the like caused by chronic gastritis, gastric and duodenal ulcer, gastroptosis, chronic diarrhea, functional dyspepsia, ulcerative colitis and the like.
Experimental data
First, case selection
(I) diagnostic criteria
1. And (3) Western diagnosis: chronic gastritis, gastric and duodenal ulcers, gastroptosis, chronic diarrhea, functional dyspepsia,
The ulcerative colitis meets the recognized Western medical diagnosis standard at home and abroad for diagnosis.
2. Chinese medicine symptom diagnosis standard:
(1) syndrome and marquis
Spleen Qi deficiency syndrome
1) And the main symptoms are as follows: inappetence, poor appetite, lassitude, abdominal distension or abdominal pain after eating, abnormal stool (loose, rotten, first hard then loose, then hard when loose), or diarrhea.
The secondary symptoms are as follows: lassitude, laziness in speaking, pale mouth, lingering abdominal pain, nausea, vomiting, nausea, borborygmus, sallow complexion, edema, weakness in defecation, pale tongue, swollen tongue with teeth marks, thin and white coating, and thready and weak pulse. Has 2 main symptoms; or 1 item of the main symptoms and 2 items of the secondary symptoms.
2) Hierarchical quantification of symptoms
Grading and quantifying standard for spleen and stomach weakness symptoms
(1) The quantitative criteria for abdominal fullness and distention are shown in table 1,
Figure BDA0002298604450000071
TABLE 1
(2) The quantitative criteria for anorexia are shown in Table 2
Is normal 0 point (min)
Mild: 2 is divided into There was no appetite, but the food consumption was significantly reduced.
Medium: 4 is divided into The appetite is not whetted, and the food consumption is reduced by below 1/3.
And (3) severe degree: 6 minutes The appetite is not whetted, and the food consumption is reduced by more than 2/3.
TABLE 2
(3) Table 3 shows the quantitative criteria for tiredness and lack of strength
Figure BDA0002298604450000072
Figure BDA0002298604450000081
TABLE 3
(4) Stool abnormality quantification criteria are shown in Table 4
And (3) normal: 0 point (min)
Mild: 1 minute (1) The stool is soft, the shape of the piles is not formed, and the stool is used 2-3 times per day.
Medium: 2 is divided into Rotten stool and stool, 4-5 times a day, or loose stool, twice a day.
And (3) severe degree: 3 points of Bian Xie peaceful, 3 times daily.
TABLE 4
(5) The quantification criteria for abdominal pain are shown in Table 5
And (3) normal: 0 point (min)
Mild: 1 minute (1) Sometimes there is dull abdominal pain, and the operation is stopped when the patient is working, and the work and rest are not affected.
Medium: 2 is divided into Sometimes dull abdominal pain, lasting no more than 2 hours.
And (3) severe degree: 3 points of The abdominal pain is obvious, the duration time does not exceed 2 hours, or the abdominal pain is continuous.
TABLE 5
(6) The mental fatigue laziness quantification standard is shown in Table 6
Is normal 0 point (min)
Mild: 1 minute (1) The spirit is not vibrating, the words are not happy and the answer is not asked.
Medium: 2 is divided into Mental fatigue, thought to sleep, laziness in speech, more questions and less answers.
And (3) severe degree: 3 points of Extreme mental fatigue and even speech.
TABLE 6
Grading the severity of the disease: the total score is mild under 5 points, moderate under 6-10 points, and severe under 11 points.
Second, inclusion criteria
1. Diseases involving western medicine: such as chronic gastritis, gastric and duodenal ulcers, gastroptosis, chronic diarrhea, functional dyspepsia, and ulcerative colitis, should meet the prescribed Chinese and Western diagnostic standards.
2. The medicine accords with the traditional Chinese medicine symptom diagnosis standard of spleen-qi deficiency.
3. The age is 18-65 years.
4. The volunteers are tested and can receive verified medicines, thereby ensuring that the patients finish the treatment course.
Third, rule of eliminating cases
1. Patients who do not meet the traditional Chinese medicine symptom diagnosis standard of spleen-qi deficiency syndrome.
2. The age is 18 or less, and 65 or more years old.
3. The cases do not belong to the range of drug action.
4. There are obvious cases accompanied with syndrome involving or merging.
5. A woman in lactating pregnancy or preparing for pregnancy.
6. Allergic constitution and people allergic to various drugs.
7. Patients with serious primary diseases such as cardiovascular diseases, liver diseases, kidney diseases, hemopoietic system diseases, endocrine system diseases, and senile dementia.
8. The critical condition of the disease makes it difficult to evaluate the effectiveness and safety of the tested drugs exactly.
Fourthly, observing items
Safety detection
1: general physical examination item examination: body temperature, respiration, heart rate, blood pressure.
2: routine examination of blood, urine and feces.
3: and (5) checking the functions of the heart, the liver and the kidney.
4: adverse reactions may occur.
(II) observation of therapeutic efficacy
1: the main symptoms of abdominal distension, stomachache, inappetence, abnormal stool, listlessness, disinclination to talk and the like after the end of the month and the improvement conditions of the related symptoms.
2: tongue pulse condition
Fifth, evaluation criteria of curative effect and safety
(I) evaluation criteria of therapeutic effects
1: the clinical recovery is that the clinical symptoms and physical signs of the spleen-qi deficiency syndrome disappear or basically disappear, and the symptom score is reduced by more than or equal to 95 percent
2: the effect is shown: the clinical symptoms and physical signs of the spleen-qi deficiency syndrome are obviously improved, and the symptom score is reduced by more than or equal to 70 percent
3: has the advantages of improved clinical symptoms and physical signs of spleen-qi deficiency syndrome, and reduced symptom integral more than or equal to 30 percent
4: and (4) invalidation: the clinical symptoms and physical signs of the spleen-qi deficiency syndrome are not obviously improved or even aggravated, and the symptom score is reduced by less than 30 percent.
Efficacy index is (pre-treatment integral of symptoms-post-treatment integral)/pre-treatment integral x 100%.
(II) Chinese medicine symptoms and sign indexes Each symptom and sign is evaluated separately.
The single clinical symptom curative effect standard is as follows:
the recovery is that the single symptom or sign disappears after the treatment.
Has obvious effect that the single symptom or sign is reduced by 2 grades after being treated.
Effective, a reduction of 1 grade after single symptom or sign treatment.
No effect, no improvement after single symptom or sign treatment.
(III) safety evaluation criteria
Level 1: safe and has no adverse reaction.
And 2, stage: is safe, and can continue to administer the drug without any treatment if adverse reaction exists.
And 3, level: has the problems of safety and moderate adverse reaction, and can be continuously administrated after being treated.
4, level: the test was discontinued due to adverse reactions.
Sixth, treatment scheme
1. Verification sample-a rice drink made according to the method of example 1.
2. The taking method comprises the following steps: it is administered orally 1 bottle each time 1 time a day.
3. The course of treatment is as follows: 4 weeks is 1 course of treatment.
4. Combining the medicines: in all cases, except the above treatments, no other drugs relevant to the treatment of the disease were used during the observation period.
Seventhly, verification results
1. General data
Selecting 120 patients meeting the traditional Chinese medicine symptom diagnosis standard of spleen-qi deficiency syndrome, wherein the observation group 1 takes the sample prepared according to the first embodiment; the observation group 2 was administered with the sample prepared in the third example.
(1) The age is shown in Table 7
Figure BDA0002298604450000111
Table 7: two age distribution charts
(2) The sex is shown in Table 8
Figure BDA0002298604450000122
Table 8: two sets of sex distribution tables
(3) Symptoms of traditional Chinese medicine
Table 9: two groups of clinical symptom distribution charts
Table 9: two groups of clinical symptom distribution charts
2. Therapeutic results
(1) The comprehensive curative effects are shown in Table 10
Table 10: comprehensive efficacy analysis
(2) The relationship between age and therapeutic effect is shown in Table 11
Figure BDA0002298604450000132
Table 11: observation of age and therapeutic Effect relationship in group 1
Table 12: the relationship between age and therapeutic effect in observation group 2 is shown in Table 12
Figure BDA0002298604450000141
Table 12: observation of age and therapeutic relationship in group 2
Eighth, safety analysis
During the verification period, no obvious adverse reaction is found, and no cases with normal before treatment and abnormal after treatment exist in the safety inspection. The rice milk beverage of the invention has no side effects such as leucocyte, lymphocyte decrease, stimulation to gastric mucosa, easy nausea, even vomiting, being not suitable for patients with gastric and duodenal ulcer, etc. after being taken for a long time.
The experimental data show that the rice milk beverage has definite curative effect on the spleen and stomach weakness, is safe to use, and has positive and obvious treatment effect on patients with the spleen and stomach weakness caused by the clinical symptoms of abdominal pain, abdominal distending pain, inappetence, anorexia, loose stool, nausea, vomiting, tiredness, hypodynamia, tiredness, disinclination to talk and the like caused by chronic gastritis, gastric and duodenal ulcer, gastroptosis, chronic diarrhea, functional dyspepsia, ulcerative colitis and the like.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (9)

1. The spleen-tonifying and stomach-nourishing rice drink is characterized by comprising, by weight, 2-5 parts of ginseng, 8-20 parts of poria cocos, 5-10 parts of Chinese yam, 5-10 parts of lotus seeds, 1-5 parts of fructus amomi, 9-20 parts of white hyacinth beans, 9-20 parts of semen coicis, 2-5 parts of orange peel, 2-5 parts of platycodon grandiflorum and 2-5 parts of liquorice, and further comprising 80-150 parts of rice, 20-30 parts of wheat, 1-4 parts of a grain stabilizer, 0-10 parts of a sweetening agent and 0-10 parts of a seasoning substance.
2. The spleen-tonifying and stomach-nourishing rice milk beverage as claimed in claim 1, wherein the grain stabilizer comprises 1-2 parts of monoglyceride, 0-1 part of cellulose and 0-1 part of sodium carboxymethylcellulose.
3. The spleen-tonifying and stomach-nourishing rice beverage as claimed in claim 1, wherein the rice is one of japonica rice, indica rice, glutinous rice, millet and black rice; the wheat is one of wheat, barley, oat, quinoa and highland barley.
4. The spleen-tonifying and stomach-nourishing rice wine beverage as claimed in claim 1, wherein the sweetener is one or more of white granulated sugar, brown sugar, sucralose and stevioside.
5. The spleen-tonifying and stomach-nourishing rice milk beverage as claimed in claim 4, wherein the flavoring substance is milk powder and/or essence.
6. The preparation method of the spleen-tonifying and stomach-nourishing rice porridge is characterized by comprising the following steps of:
s1, weighing 2-5 parts of ginseng, 8-20 parts of poria cocos, 5-10 parts of Chinese yam, 5-10 parts of lotus seed, 1-5 parts of fructus amomi, 9-20 parts of white hyacinth bean, 9-20 parts of semen coicis, 2-5 parts of orange peel, 2-5 parts of platycodon grandiflorum, 2-5 parts of liquorice, 80-150 parts of rice and 20-30 parts of wheat, respectively performing immersion washing to remove impurities;
s2, respectively crushing ginseng, Chinese yam, lotus seeds, fructus amomi, white hyacinth beans and coix seeds, sieving the crushed materials with a 80-mesh sieve, and respectively extracting and concentrating the sieved materials to obtain the ginseng, Chinese yam, lotus seeds, fructus amomi, white hyacinth beans and coix seeds with the concentration ratio of 1: 1, a concentrated solution; respectively crushing poria cocos, platycodon grandiflorum, liquorice and orange peel, extracting twice, combining extracting solutions obtained after twice extraction, and concentrating to obtain a concentrate with a concentration ratio of 1: 1, a concentrated solution;
s3, mixing 80-150 parts of rice, 20-30 parts of wheat and 1-4 parts of a grain stabilizer or a sweetening agent, finely grinding, then mixing 2-5 parts of a ginseng concentrated solution, 8-20 parts of a poria cocos concentrated solution, 5-10 parts of a Chinese yam concentrated solution, 5-10 parts of a lotus seed concentrated solution, 1-5 parts of a fructus amomi concentrated solution, 9-20 parts of a white hyacinth bean concentrated solution, 9-20 parts of a semen coicis concentrated solution, 2-5 parts of an orange peel concentrated solution, 2-5 parts of a platycodon grandiflorum concentrated solution and 2-5 parts of a liquorice concentrated solution, adding water, uniformly mixing, and finely grinding to obtain a mixed solution;
s4, emulsifying and homogenizing the mixed solution by using a homogenizer, and then pre-gelatinizing by using a gelatinizing device to obtain a cured mixture;
s5, crushing the cooled cured mixture by using a high-pressure homogenizer to obtain a gelatinized and crushed mixture;
and S6, carrying out ultrahigh-temperature instantaneous sterilization on the gelatinized and crushed mixture, and carrying out low-temperature aseptic filling to obtain the spleen-tonifying and stomach-nourishing rice dilute beverage.
7. The method for preparing the spleen-invigorating and stomach-nourishing rice porridge beverage as claimed in claim 7, wherein in S2, the raw materials of Poria cocos, Platycodon grandiflorum, Glycyrrhiza uralensis and orange peel are extracted twice, the first extraction time is 120min, and the extraction temperature is 100 ℃; the second extraction time is 90min, and the extraction temperature is 100 deg.C.
8. The preparation method of the spleen-tonifying and stomach-nourishing rice porridge as claimed in claim 7, wherein in S3, the Baume degree of the slurry of the mixed solution is 6-23.
9. The preparation method of the spleen-tonifying and stomach-nourishing rice porridge beverage as claimed in claim 7, wherein in S6, the temperature for ultra-high temperature instant sterilization is 135-180 ℃ for 5-10S.
CN201911212833.3A 2019-12-02 2019-12-02 Spleen-tonifying and stomach-nourishing rice-containing dilute beverage and preparation method thereof Pending CN110754593A (en)

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