CN110753845B - 用于实体瘤诊断的生物标志物绝对定量的方法和装置 - Google Patents
用于实体瘤诊断的生物标志物绝对定量的方法和装置 Download PDFInfo
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- CN110753845B CN110753845B CN201880039041.8A CN201880039041A CN110753845B CN 110753845 B CN110753845 B CN 110753845B CN 201880039041 A CN201880039041 A CN 201880039041A CN 110753845 B CN110753845 B CN 110753845B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Data Mining & Analysis (AREA)
- Databases & Information Systems (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762526425P | 2017-06-29 | 2017-06-29 | |
| US62/526,425 | 2017-06-29 | ||
| PCT/US2018/040075 WO2019006156A1 (en) | 2017-06-29 | 2018-06-28 | APPARATUS AND METHOD FOR ABSOLUTE QUANTIFICATION OF BIOMARKERS FOR SOLID TUMOR DIAGNOSIS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110753845A CN110753845A (zh) | 2020-02-04 |
| CN110753845B true CN110753845B (zh) | 2023-08-22 |
Family
ID=64734814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880039041.8A Active CN110753845B (zh) | 2017-06-29 | 2018-06-28 | 用于实体瘤诊断的生物标志物绝对定量的方法和装置 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10788484B2 (https=) |
| EP (1) | EP3646328A4 (https=) |
| JP (1) | JP7194128B2 (https=) |
| KR (1) | KR102502745B1 (https=) |
| CN (1) | CN110753845B (https=) |
| CA (1) | CA3101968A1 (https=) |
| SG (1) | SG11201908865WA (https=) |
| WO (1) | WO2019006156A1 (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201602882VA (en) | 2013-10-18 | 2016-05-30 | Univ Health Network | Treatment for pancreatic cancer |
| KR20180135481A (ko) * | 2016-04-21 | 2018-12-20 | 이매틱스 바이오테크놀로지스 게엠베하 | 흑색종 및 기타 암에 대한 면역요법 |
| DE102016209871A1 (de) | 2016-06-06 | 2017-12-07 | Robert Bosch Gmbh | Stanzvorrichtung und Verfahren zum Stanzen eines Lumens und Implantieren einer Implantateinrichtung |
| DE102018201030B4 (de) * | 2018-01-24 | 2025-10-16 | Kardion Gmbh | Magnetkuppelelement mit magnetischer Lagerungsfunktion |
| DE102018206731A1 (de) | 2018-05-02 | 2019-11-07 | Kardion Gmbh | Vorrichtung zur induktiven Energieübertragung in einen menschlichen Körper und Verwendung der Vorrichtung |
| DE102018206724A1 (de) | 2018-05-02 | 2019-11-07 | Kardion Gmbh | Energieübertragungssystem und Verfahren zur drahtlosen Energieübertragung |
| DE102018206727A1 (de) | 2018-05-02 | 2019-11-07 | Kardion Gmbh | Energieübertragungssystem und Empfangseinheit zur drahtlosen transkutanen Energieübertragung |
| DE102018206754A1 (de) | 2018-05-02 | 2019-11-07 | Kardion Gmbh | Verfahren und Vorrichtung zur Bestimmung der Temperatur an einer Oberfläche sowie Verwendung des Verfahrens |
| DE102018206750A1 (de) | 2018-05-02 | 2019-11-07 | Kardion Gmbh | Vorrichtung zur induktiven Energieübertragung in einen menschlichen Körper und deren Verwendung |
| DE102018206725A1 (de) | 2018-05-02 | 2019-11-07 | Kardion Gmbh | Empfangseinheit, Sendeeinheit, Energieübertragungssystem und Verfahren zur drahtlosen Energieübertragung |
| DE102018207575A1 (de) | 2018-05-16 | 2019-11-21 | Kardion Gmbh | Magnetische Stirndreh-Kupplung zur Übertragung von Drehmomenten |
| DE102018207611A1 (de) | 2018-05-16 | 2019-11-21 | Kardion Gmbh | Rotorlagerungssystem |
| DE102018207594A1 (de) | 2018-05-16 | 2019-11-21 | Kardion Gmbh | Rotor, Magnetkupplungsvorrichtung, Elektromotor für ein Herzunterstützungssystem, Pumpeneinheit für ein Herzunterstützungssystem sowie Verfahren zum Herstellen eines Rotors |
| DE102018208541A1 (de) | 2018-05-30 | 2019-12-05 | Kardion Gmbh | Axialpumpe für ein Herzunterstützungssystem und Verfahren zum Herstellen einer Axialpumpe für ein Herzunterstützungssystem |
| DE102018208538A1 (de) | 2018-05-30 | 2019-12-05 | Kardion Gmbh | Intravasale Blutpumpe und Verfahren zur Herstellung von elektrischen Leiterbahnen |
| DE102018208549A1 (de) | 2018-05-30 | 2019-12-05 | Kardion Gmbh | Elektronikmodul für ein Herzunterstützungssystem und Verfahren zum Herstellen eines Elektronikmoduls für ein Herzunterstützungssystem |
| DE102018208550A1 (de) | 2018-05-30 | 2019-12-05 | Kardion Gmbh | Leitungsvorrichtung zum Leiten eines Blutstroms für ein Herzunterstützungssystem, Herzunterstützungssystem und Verfahren zum Herstellen einer Leitungsvorrichtung |
| DE102018208539A1 (de) | 2018-05-30 | 2019-12-05 | Kardion Gmbh | Motorgehäusemodul zum Abdichten eines Motorraums eines Motors eines Herzunterstützungssystems und Herzunterstützungssystem und Verfahren zum Montieren eines Herzunterstützungssystems |
| DE102018208555A1 (de) | 2018-05-30 | 2019-12-05 | Kardion Gmbh | Vorrichtung zum Verankern eines Herzunterstützungssystems in einem Blutgefäß, Verfahren zum Betreiben und Herstellverfahren zum Herstellen einer Vorrichtung und Herzunterstützungssystem |
| DE102018210058A1 (de) | 2018-06-21 | 2019-12-24 | Kardion Gmbh | Statorschaufelvorrichtung zur Strömungsführung eines aus einer Austrittsöffnung eines Herzunterstützungssystems ausströmenden Fluids, Herzunterstützungssystem mit Statorschaufelvorrichtung, Verfahren zum Betreiben einer Statorschaufelvorrichtung und Herstellverfahren |
| DE102018210076A1 (de) | 2018-06-21 | 2019-12-24 | Kardion Gmbh | Verfahren und Vorrichtung zum Erkennen eines Verschleißzustands eines Herzunterstützungssystems, Verfahren und Vorrichtung zum Betreiben eines Herzunterstützungssystems und Herzunterstützungssystem |
| WO2020010163A1 (en) * | 2018-07-02 | 2020-01-09 | Tempus Labs, Inc. | 3d radiomic platform for imaging biomarker development |
| DE102018211297A1 (de) | 2018-07-09 | 2020-01-09 | Kardion Gmbh | Herzunterstützungssystem und Verfahren zur Überwachung der Integrität einer Haltestruktur eines Herzunterstützungssystems |
| DE102018211328A1 (de) | 2018-07-10 | 2020-01-16 | Kardion Gmbh | Laufradgehäuse für ein implantierbares, vaskuläres Unterstützungssystem |
| DE102018211327A1 (de) | 2018-07-10 | 2020-01-16 | Kardion Gmbh | Laufrad für ein implantierbares, vaskuläres Unterstützungssystem |
| DE102018212153A1 (de) | 2018-07-20 | 2020-01-23 | Kardion Gmbh | Zulaufleitung für eine Pumpeneinheit eines Herzunterstützungssystems, Herzunterstützungssystem und Verfahren zum Herstellen einer Zulaufleitung für eine Pumpeneinheit eines Herzunterstützungssystems |
| EP3833410B1 (de) | 2018-08-07 | 2025-10-08 | Kardion GmbH | Lagervorrichtung für ein herzunterstützungssystem und verfahren zum spülen eines zwischenraums in einer lagervorrichtung für ein herzunterstützungssystem |
| WO2021087477A1 (en) | 2019-11-01 | 2021-05-06 | Quanticision Diagnostics Inc. | Method for diagnosis of cancer based on quantitative biomarkers and a database thereof |
| AU2021207312A1 (en) * | 2020-01-17 | 2022-06-30 | Universität Zürich | Single cell pathology analysis of tumour samples |
| DE102020102474A1 (de) | 2020-01-31 | 2021-08-05 | Kardion Gmbh | Pumpe zum Fördern eines Fluids und Verfahren zum Herstellen einer Pumpe |
| AU2021340802A1 (en) | 2020-09-14 | 2023-05-18 | Kardion Gmbh | Cardiovascular support pump having an impeller with a variable flow area |
| US11699551B2 (en) | 2020-11-05 | 2023-07-11 | Kardion Gmbh | Device for inductive energy transmission in a human body and use of the device |
| AU2021383931A1 (en) | 2020-11-20 | 2023-07-06 | Kardion Gmbh | Mechanical circulatory support system with guidewire aid |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1675550A (zh) * | 2002-08-01 | 2005-09-28 | Mtm实验室公司 | 基于溶液的检测方法 |
| CN103562409A (zh) * | 2011-05-25 | 2014-02-05 | 诺华股份有限公司 | 肺癌的生物标志物 |
| WO2016172216A1 (en) * | 2015-04-20 | 2016-10-27 | The Methodist Hospital | Use of soluble crkl compositions as breast cancer biomarkers and predictors of cancer metastasis |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1544618B1 (en) * | 2002-07-25 | 2009-03-18 | Ajinomoto Co., Inc. | Method of analyzing protein |
| DE102005023011A1 (de) * | 2005-05-19 | 2006-11-23 | Qiagen Gmbh | Quantitative Proteinbestimmung von Formalin fixiertem Gewebe |
| CA2653398A1 (en) * | 2006-05-26 | 2007-12-06 | Board Of Regents, The University Of Texas System | Reverse phase protein array, protein activation and expression signatures, and associated methods |
| GB0611669D0 (en) * | 2006-06-13 | 2006-07-19 | Astrazeneca Uk Ltd | Mass spectrometry biomarker assay |
| WO2008075664A1 (ja) * | 2006-12-21 | 2008-06-26 | Ajinomoto Co., Inc. | 癌の評価方法、ならびに癌評価装置、癌評価方法、癌評価システム、癌評価プログラムおよび記録媒体 |
| EP2660596B1 (en) * | 2008-10-02 | 2018-06-13 | Gaia Medical Institute | Health test for a broad spectrum of health problems |
| EP2239675A1 (en) | 2009-04-07 | 2010-10-13 | BIOCRATES Life Sciences AG | Method for in vitro diagnosing a complex disease |
| JP2013099253A (ja) * | 2010-03-11 | 2013-05-23 | Intec Systems Institute Inc | 肺癌または子宮頸癌の診断マーカー |
| US8293487B1 (en) | 2012-01-06 | 2012-10-23 | Jiandi Zhang | Zestern, a simple, fast, specific and quantifiable improvement of immunodetection process |
| US9933418B2 (en) * | 2015-05-26 | 2018-04-03 | Quanticision Diagnostics Inc. | Multi-unit plate for electroblotting and immunoblot analysis |
| JP7144935B2 (ja) * | 2015-05-29 | 2022-09-30 | ジェネンテック， インコーポレイテッド | 癌のための治療方法及び診断方法 |
| AU2017278261A1 (en) | 2016-06-05 | 2019-01-31 | Berg Llc | Systems and methods for patient stratification and identification of potential biomarkers |
-
2018
- 2018-06-28 JP JP2019571981A patent/JP7194128B2/ja active Active
- 2018-06-28 CA CA3101968A patent/CA3101968A1/en active Pending
- 2018-06-28 US US16/022,259 patent/US10788484B2/en active Active
- 2018-06-28 SG SG11201908865W patent/SG11201908865WA/en unknown
- 2018-06-28 KR KR1020207002341A patent/KR102502745B1/ko active Active
- 2018-06-28 EP EP18824958.5A patent/EP3646328A4/en active Pending
- 2018-06-28 WO PCT/US2018/040075 patent/WO2019006156A1/en not_active Ceased
- 2018-06-28 CN CN201880039041.8A patent/CN110753845B/zh active Active
-
2020
- 2020-09-28 US US17/035,607 patent/US20210011010A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1675550A (zh) * | 2002-08-01 | 2005-09-28 | Mtm实验室公司 | 基于溶液的检测方法 |
| CN103562409A (zh) * | 2011-05-25 | 2014-02-05 | 诺华股份有限公司 | 肺癌的生物标志物 |
| WO2016172216A1 (en) * | 2015-04-20 | 2016-10-27 | The Methodist Hospital | Use of soluble crkl compositions as breast cancer biomarkers and predictors of cancer metastasis |
Non-Patent Citations (1)
| Title |
|---|
| Molecular Analysis of HER2 Signaling in Human Breast Cancer by Functional Protein Pathway Activation Mapping;Julia D. Wulfkuhle1 等;《CLINICAL CANCER RESEARCH》;20121201;第18卷(第23期);第1-21页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP7194128B2 (ja) | 2022-12-21 |
| US20210011010A1 (en) | 2021-01-14 |
| CN110753845A (zh) | 2020-02-04 |
| CA3101968A1 (en) | 2019-01-03 |
| US20190004037A1 (en) | 2019-01-03 |
| US10788484B2 (en) | 2020-09-29 |
| KR102502745B1 (ko) | 2023-02-23 |
| JP2020526747A (ja) | 2020-08-31 |
| WO2019006156A1 (en) | 2019-01-03 |
| EP3646328A1 (en) | 2020-05-06 |
| SG11201908865WA (en) | 2019-10-30 |
| KR20200020906A (ko) | 2020-02-26 |
| EP3646328A4 (en) | 2021-04-21 |
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Effective date of registration: 20230609 Address after: 264670 No. 39 Science and Technology Avenue, Yantai High-tech Zone, Shandong Province Applicant after: YANTAI ZESTERN BIOTECHNIQUE CO.,LTD. Address before: 264003 Baiwei international building, No. 1295, Gangcheng East Street, Laishan District, Yantai City, Shandong Province Applicant before: QUANTICISION DIAGNOSTICS Inc. |
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