CN110747121A - Chinese herbal medicine extraction element - Google Patents

Chinese herbal medicine extraction element Download PDF

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CN110747121A
CN110747121A CN201911036847.4A CN201911036847A CN110747121A CN 110747121 A CN110747121 A CN 110747121A CN 201911036847 A CN201911036847 A CN 201911036847A CN 110747121 A CN110747121 A CN 110747121A
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fermentation tank
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刘本德
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    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • C12M27/06—Stirrer or mobile mixing elements with horizontal or inclined stirrer shaft or axis
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    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/20—Degassing; Venting; Bubble traps
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    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
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    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00—Means for pre-treatment of biological substances
    • C12M45/02—Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting

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Abstract

The invention discloses a Chinese herbal medicine extraction device, which comprises a fermentation tank, a stirring device, an ultrasonic device and a pipeline system; the fermentation tank comprises a fermentation tank body, a fermentation tank jacket layer and a fermentation tank body cover, wherein the fermentation tank jacket layer is positioned in the fermentation tank body; the cover of the fermentation tank body is provided with an exhaust port and a sampling port; a connecting port is arranged in the middle of the cover of the fermentation tank body; the stirring device comprises a stirring motor and a stirring shaft; the ultrasonic device is arranged on the side of the cover of the fermentation tank body, and the ultrasonic end of the ultrasonic device is connected with the connecting port; the pipeline system comprises an air inlet pipeline, a water outlet pipeline and a sewage discharge pipeline, wherein the air inlet pipeline comprises a steam pipeline and a gas pipeline which are arranged in parallel, and the steam pipeline and the gas pipeline are communicated with an air inlet through an air inlet pipe at a junction. The extraction rate of the Chinese herbal medicine extraction device is as high as 98.6%.

Description

Chinese herbal medicine extraction element
Technical Field
The invention relates to the technical field of separation devices, in particular to a Chinese herbal medicine extraction device.
Background
The chemical components contained in the traditional Chinese medicine are very complex, and not only contain various effective components, but also have ineffective components and also contain toxic components. Extracting the effective components of the effective monomers, and further separating and purifying the effective components to obtain the effective monomers is an important content in the research field of traditional Chinese medicines. The extraction of the traditional Chinese medicine is to extract the effective components in the traditional Chinese medicine to the maximum extent by utilizing certain technologies, so that the internal quality and the clinical treatment effect of the traditional Chinese medicine preparation are improved, and the effect of the traditional Chinese medicine is exerted to the maximum extent.
The extraction of the whole components of the plants is another new direction of the technical development. The traditional Chinese medicine always takes all Chinese herbal medicines as medicaments to be decocted. Modern medicine has extracted a component of Chinese herbal medicine which is effective for some symptoms or bacteria for the first few years, but after a while, the therapeutic effect of the component on symptoms is reduced and the bacteria also produce antibodies. This does not occur when the whole ingredients of the Chinese herbal medicine are pulverized for treatment. On the other hand, some diseases can be treated by using certain extracted components in the Chinese herbal medicines, and the components are toxic and have harmful effect on human bodies when being eaten. However, if all the components of the plant are taken together as the medicine, the curative effect is not changed, and other components contained in the plant can relieve the toxicity of the therapeutic components. In the aspect of food and health care products, when certain effective components in the plants are extracted, other components left in the plants are wasted, and the wasted components also contain a plurality of substances beneficial to human bodies. Therefore, the extraction of the whole components of the plant has important significance. However, the extraction rate of all the components of the existing Chinese herbal medicine extraction device is not high, so that the development of a Chinese herbal medicine extraction device with high extraction rate becomes a technical problem to be solved urgently.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a Chinese herbal medicine extraction device which integrates a gas pipeline and an ultrasonic device; therefore, the wall breaking rate of the cell wall can reach 98.6% by the combination of the introduced inert gas and the ultrasonic wave.
The invention is realized by the following steps:
the invention aims to provide a Chinese herbal medicine extraction device, which comprises a fermentation tank, a stirring device, an ultrasonic device and a pipeline system;
the fermentation tank comprises a fermentation tank body, a fermentation tank jacket layer and a fermentation tank body cover, wherein the fermentation tank jacket layer is positioned in the fermentation tank body; the fermentation tank body cover is detachably connected with the fermentation tank body, and an exhaust port and a sampling port are formed in the fermentation tank body cover; a connecting port is arranged in the middle of the cover of the fermentation tank body;
the stirring device comprises a stirring motor and a stirring shaft; one end of the stirring shaft is positioned in the fermentation tank body, and the other end of the stirring shaft is connected with the power output end of the stirring motor;
the ultrasonic device is arranged on the side of the cover of the fermentation tank body, and the ultrasonic end of the ultrasonic device is connected with a connecting port of the cover of the fermentation tank body;
the pipeline system comprises an air inlet pipeline, a water outlet pipeline and a sewage discharge pipeline, wherein the water inlet pipeline is communicated with the water inlet, the water outlet pipeline is communicated with the water outlet, and the sewage discharge pipeline is communicated with a sewage discharge outlet; the air inlet pipeline comprises a steam pipeline and an air pipeline which are arranged in parallel, and the steam pipeline and the air pipeline are communicated with the air inlet at the junction through an air inlet pipe;
in the Chinese herbal medicine extraction process, introducing inert gas through the gas inlet pipeline, and turning on the ultrasonic device to carry out ultrasonic treatment until the added inert gas is completely subjected to ultrasonic treatment, wherein the ultrasonic frequency is 18-22 KHz, and the ultrasonic time is 3-5 min; and after the ultrasonic treatment is finished, the pressure in the fermentation tank is 0.3-0.7 MPa.
Compared with the prior art, the invention has the following advantages and effects:
the invention provides a Chinese herbal medicine extraction device, wherein an air inlet pipeline comprises a steam pipeline and a gas pipeline which are arranged in parallel, when the device works, a Chinese herbal medicine feed port is added (and some wall-breaking reaction liquid is added), inert gas is firstly introduced through the gas pipeline, an ultrasonic device is started to carry out ultrasonic treatment until the added inert gas is volatilized, and the ultrasonic treatment is finished; the traditional Chinese herbal medicine extraction device adopts steam with higher temperature for heating and sterilizing; and only steam heated to 50-60 ℃ is needed, and the ultrasonic wave plays a role in inactivation, so that steam with higher temperature is not needed. The wall breaking rate of the cell wall can reach 98.6% by adopting the combination of the introduced inert gas and the ultrasonic wave.
Drawings
FIG. 1 is a schematic structural diagram of an apparatus for extracting Chinese herbal medicines according to an embodiment of the present invention;
FIG. 2 is a schematic diagram of a part of a Chinese herbal medicine extracting apparatus according to an embodiment of the present invention;
1. a fermentation tank; 11. a fermentation tank body; 12. a fermentation tank jacket layer; 13. a cover of the fermentation tank body; 14. an air inlet; 15. a water inlet; 16. a feed inlet; 17. a sewage draining outlet; 18. a water outlet; 13-1, an exhaust port; 13-2, a sampling port; 13-3, connecting ports; 19. a temperature sensor interface; 2. a stirring device; 21. a stirring motor; 22. a stirring shaft; 3. an ultrasonic device; 4. a piping system; 41. an air inlet pipe; 42. a vapor filter; 43. a pressure reducing valve; 44. a sterilizing filter; q1, intake valve; q2, a second steam switch valve; q3, third gas switching valve; q4, exhaust valve; q5, connecting pipe switch valve; q6, a second gas switching valve; q7, degerming filter switch valve; q8, a first steam switch valve; q9, first gas switching valve; q10, a steam valve I is communicated with a sampling port; q11, a steam valve II is communicated with a sampling port; q12, a sampling port exhaust valve; q13, a blowdown valve; q14, water inlet valve; q15, water outlet valve; q16, exhaust valve.
Detailed Description
Examples
The embodiment provides a Chinese herbal medicine extraction device, which comprises a fermentation tank 1, a stirring device 2, an ultrasonic device 3 and a pipeline system 4;
the fermentation tank 1 comprises a fermentation tank body 11, a fermentation tank jacket layer 12 and a fermentation tank body cover 13, wherein the fermentation tank body is positioned in the fermentation tank body, and the fermentation tank is provided with an air inlet 14, a water inlet 15, a feed inlet 16, a sewage outlet 17 and a water outlet 18; the fermentation tank body cover 13 is detachably connected with the fermentation tank body 11, and an exhaust port 13-1 and a sampling port 13-2 are arranged on the fermentation tank body cover 13; a connecting port 13-3 is arranged in the middle of the cover of the fermentation tank body;
the stirring device 2 comprises a stirring motor 21 and a stirring shaft 22; one end of the stirring shaft 22 is positioned in the fermentation tank body 11, and the other end of the stirring shaft is connected with the power output end of the stirring motor 21;
the ultrasonic device 3 is arranged on the side of the fermentation tank body cover 13, and the ultrasonic end of the ultrasonic device 3 is connected with a connecting port 13-3 of the fermentation tank body cover 13 (when the ultrasonic device 3 is not connected with the connecting port 13-3, a connecting cover which can be detachably connected is arranged at the connecting port 13-3);
the pipeline system 4 comprises an air inlet pipeline, a water outlet pipeline and a sewage discharge pipeline, wherein the water inlet pipeline is communicated with the water inlet, the water outlet pipeline is communicated with the water outlet, and the sewage discharge pipeline is communicated with a sewage discharge outlet; the air inlet pipeline comprises a steam pipeline and a gas pipeline which are arranged in parallel, and the steam pipeline and the gas pipeline are communicated with the air inlet 14 at a junction through an air inlet pipe 41.
The Chinese herbal medicine extraction device provided by the invention is characterized in that the air inlet pipeline comprises a steam pipeline and an air pipeline which are arranged in parallel, and when a fermentation tank is empty, the steam pipeline is opened to introduce steam for sterilization; during working, the Chinese herbal medicine feed inlet is added (and some wall-breaking reaction liquid is added) and the stirring device 2 is started to stir, inert gas is introduced through a gas pipeline, meanwhile, the ultrasonic device 3 is started to carry out ultrasonic treatment until the added inert gas is volatilized, and the ultrasonic treatment is finished;
when the traditional Chinese herbal medicine extraction device is used for extracting Chinese herbal medicines, steam with higher temperature is needed for heating and sterilizing by adopting steam; and steam heated to 50-60 ℃ is only needed, inert gas (such as argon) is introduced through a gas pipeline, an ultrasonic device is started to perform ultrasonic treatment at the same time until the added inert gas is volatilized, the ultrasonic treatment is finished, the ultrasonic wave plays a role in inactivation, so that steam with higher temperature is not needed (the high-temperature steam sterilization is adopted only when a fermentation tank is empty), and the combination of the introduced inert gas (argon gas) + the ultrasonic wave is favorable for extracting Chinese herbal medicines: argon is added into the fermentation tank, and pressure is increased to ensure that the wall-breaking reaction liquid added firstly is fully contacted with cell walls; secondly, the argon gas has stable property, and almost no heating effect is generated by pressurization, which is beneficial to protecting effective pharmacological components in cells from being damaged; thirdly, micro-cavitation is formed under the action of ultrasonic waves, cell walls can be damaged, the temperature rise effect caused by the action of the ultrasonic waves is reduced due to the fact that argon is inert gas, the cell walls can be deformed, intracellular components can be analyzed, and effective pharmacological components can be guaranteed not to be damaged due to the low temperature; fourthly, after the ultrasonic action is finished, the added argon gas is basically volatilized, and the next extraction and separation are not influenced; fifthly, inert gas and ultrasonic waves are adopted, and bubbles formed by the gas are broken like a small bomb under the action of the ultrasonic waves, so that the breakage of cell walls is facilitated. Thereby obtaining the Chinese herbal medicine extract.
Preferably, the steam pipeline and the gas pipeline are communicated through a connecting pipe, and a connecting pipe switch valve Q5 is arranged on the connecting pipe.
Preferably, the air inlet pipe is provided with an air inlet valve Q1 at the junction, and the steam pipeline is provided with a first steam switch valve Q8, a steam filter and a second steam switch valve Q2 in sequence; and the gas pipeline is sequentially provided with a first gas switch valve Q9, a pressure reducing valve, a second gas switch valve Q6, a sterilizing filter and a third gas switch valve Q3.
Preferably, the outlet end of the sterilizing filter is provided with a sterilizing filter switch valve Q7, and the outlet end of the sterilizing filter is connected with the sewage pipeline through the sterilizing filter switch valve Q7.
Preferably, the stirring paddle is arranged on the stirring shaft and is arranged in the fermentation tank body; the stirring paddles are arranged in a plurality of and are arranged on the stirring shaft in a cross manner. The stirring paddle is in a cross-shaped arrangement, so that the stirring area is increased, the working time is reduced, the working efficiency is improved, and the stirring quality is ensured.
Preferably, a temperature sensor interface 19 is also arranged on the fermentation tank. The temperature detection is convenient.
Preferably, the fermentation tank is also provided with a pressure gauge. The pressure in the fermentation tank can be conveniently detected.
Preferably, a lamp sight glass is further arranged on the fermentation tank. The fermentation state in the fermentation tank can be observed conveniently.
The use method of the Chinese herbal medicine extraction device provided by the invention comprises the following steps:
1. sterilization of pipelines
The Q8 valve, Q5 valve, and Q7 valve are opened and the vapor on the gas line passes through the vapor filter 42 and then into the sterilizing filter 44. In the air-sterilizing process, the Q3 valve and the exhaust valve Q4 at the lower end of the sterilizing filter 44 are slightly opened to drain condensed water. The air-slaking time lasts for about 30 minutes, and when the equipment is started after being used for the first time or not used for a long time, intermittent air-slaking is preferably adopted, namely air-slaking is carried out once every 3 to 5 hours after the first air-slaking so as to eliminate spores. And (3) ventilating and drying the steam filter 42 and the sterilizing filter 44 after air sterilization for about 20-30 minutes, and then closing the valve. Since the pressure reducing valve 43 cannot be steam-sterilized, the Q9 and Q6 valves are not opened.
2. Fermentation tank air eliminator
Before the fermentation tank is empty, opening a drain valve Q13 (so that the pressure in the jacket is not overpressure), closing Q3, slightly opening Q4, opening a steam valve Q2, opening Q1 and introducing steam into the tank; and opening the Q10 and the Q11 to introduce steam into the tank through the sampling port.
The feed inlet 16, the exhaust valve Q16 and the valve Q13 on the sewage discharge pipeline on the tank are slightly opened, so that steam is discharged through the valves, timing is started after the humidity reaches 122 ℃, the opening degrees of the valves Q16, Q1 and Q10 are adjusted, the temperature in the tank is kept between 122 ℃ and 128 ℃ (the pressure is generally between 0.11 and 0.15MPa), and the temperature and the pressure of air digestion can be adjusted according to the process.
And when the time reaches 30-40 minutes, closing Q1, Q4 and Q10, then closing Q2 and Q11, opening valves Q3 and Q1 on the air inlet pipeline to introduce air into the tank for cooling, and keeping the positive pressure in the tank between 0.03MPa and 0.05 MPa.
When the rapid cooling is needed, the sewage discharge valve Q13 is closed, the water inlet valve Q14 is opened to lead cooling water to the jacket for cooling, and the cooling water is closed after the temperature reaches the normal temperature. In special cases, intermittent air-blowing (air-blowing once every 3-5 hours to eliminate spores) can be adopted.
3. Adding culture medium and inoculating
(1) After the air digestion is finished, the air inlet valve Q1 is closed, the Q16 is opened to remove the pressure in the fermentation tank, and Chinese herbal medicines and the wall breaking reaction liquid are added into the fermentation tank, so that the Chinese herbal medicines are immersed in the wall breaking reaction liquid.
Preferably, the wall-breaking reaction solution comprises a cell wall-dissolving enzyme and a microbial agent; the cell wall lytic enzyme comprises at least one of cellulase, hemicellulase, pectinase protease and lipase; the microbial agent comprises at least one of fungi and bacillus subtilis.
Preferably, the weight volume ratio of the Chinese herbal medicines to the wall breaking reaction liquid is 1 kg: 2-5L.
(2) Starting the mechanical stirring device, rotating at low speed to uniformly mix the materials in the tank.
(3) Opening a jacket blowdown valve Q13 and a steam valve Q10, and preheating the culture medium in the tank (preheating by jacket steam introduction) to 50-60 ℃; or injecting hot water into a jacket of the fermentation tank through the water inlet pipe to keep the temperature at 50-60 ℃;
(4) then, the combination of the introduced inert gas (argon gas) and ultrasonic waves is adopted for inactivation and the extraction of the Chinese herbal medicines. The method specifically comprises the following steps:
opening valves Q9, Q6, Q3 and Q1, introducing inert gas (such as argon) through a gas pipeline, simultaneously starting the ultrasonic device 3 to carry out ultrasonic treatment until the added inert gas is volatilized, and finishing the ultrasonic treatment, wherein the ultrasonic frequency is 18-22 KHz, and the ultrasonic time is 3-5 min; after the ultrasonic treatment is finished, the pressure in the closed container is 0.3-0.7 MPa; the invention adopts high-temperature steam for sterilization only when the fermentation tank is empty, and the combination of the introduced inert gas (argon gas) and the ultrasonic wave is favorable for extracting the Chinese herbal medicine, thereby obtaining the Chinese herbal medicine extracting solution:
extracting the obtained traditional Chinese medicine extracting solution as required: after the ultrasonic treatment is finished, the pressure in the fermentation tank is removed, the cover 13 of the fermentation tank body is opened, all the materials (namely the Chinese herbal medicine extracting solution) after the wall breaking is finished are removed, and the materials are transferred to a microwave extraction instrument for microwave extraction; the heating time of the microwave extraction instrument is 1-2 min; the frequency of the microwave extraction is 300-500 MHz; filtering and separating to obtain the desired extract.
The invention is not to be considered as limited to the particular embodiments shown, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (8)

1. A Chinese herbal medicine extraction device is characterized by comprising a fermentation tank, a stirring device, an ultrasonic device and a pipeline system;
the fermentation tank comprises a fermentation tank body, a fermentation tank jacket layer and a fermentation tank body cover, wherein the fermentation tank jacket layer is positioned in the fermentation tank body; the fermentation tank body cover is detachably connected with the fermentation tank body, and an exhaust port and a sampling port are formed in the fermentation tank body cover; a connecting port is arranged in the middle of the cover of the fermentation tank body;
the stirring device comprises a stirring motor and a stirring shaft; one end of the stirring shaft is positioned in the fermentation tank body, and the other end of the stirring shaft is connected with the power output end of the stirring motor;
the ultrasonic device is arranged on the side of the cover of the fermentation tank body, and the ultrasonic end of the ultrasonic device is connected with a connecting port of the cover of the fermentation tank body;
the pipeline system comprises an air inlet pipeline, a water outlet pipeline and a sewage discharge pipeline, wherein the water inlet pipeline is communicated with the water inlet, the water outlet pipeline is communicated with the water outlet, and the sewage discharge pipeline is communicated with a sewage discharge outlet; the air inlet pipeline comprises a steam pipeline and an air pipeline which are arranged in parallel, and the steam pipeline and the air pipeline are communicated with the air inlet at the junction through an air inlet pipe;
in the Chinese herbal medicine extraction process, introducing inert gas through the gas inlet pipeline, and turning on the ultrasonic device to carry out ultrasonic treatment until the added inert gas is completely subjected to ultrasonic treatment, wherein the ultrasonic frequency is 18-22 KHz, and the ultrasonic time is 3-5 min; and after the ultrasonic treatment is finished, the pressure in the fermentation tank is 0.3-0.7 MPa.
2. The chinese herbal medicine extracting apparatus as set forth in claim 1, wherein the steam line and the gas line are communicated through a connection pipe, and a connection pipe switching valve Q5 is provided on the connection pipe.
3. The device for extracting Chinese herbal medicine according to claim 1, wherein said air intake pipe is provided with an air intake valve Q1 at said junction, and said steam pipe is provided with a first steam switch valve Q8, a steam filter and a second steam switch valve Q2 in sequence; and the gas pipeline is sequentially provided with a first gas switch valve Q9, a pressure reducing valve, a second gas switch valve Q6, a sterilizing filter and a third gas switch valve Q3.
4. The herb extraction apparatus as set forth in claim 3, wherein said sterilizing filter has an outlet end provided with a sterilizing filter switch valve Q7, said outlet end being connected to said sewage line through said sterilizing filter switch valve Q7.
5. The device for extracting Chinese herbal medicine according to claim 1, wherein the stirring paddle is installed on the stirring shaft and is arranged in the tank body of the fermentation tank; the stirring paddles are arranged in a plurality of and are arranged on the stirring shaft in a cross manner.
6. The device for extracting chinese herbal medicine of claim 1, wherein said fermenter further comprises a temperature sensor port.
7. The device for extracting chinese herbal medicine of claim 1, wherein said fermenter is further provided with a pressure gauge.
8. The herb extraction device of claim 1, wherein said fermenter further comprises a light viewing mirror.
CN201911036847.4A 2019-10-29 2019-10-29 Chinese herbal medicine extraction element Pending CN110747121A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115806744A (en) * 2022-11-16 2023-03-17 浙江农林大学 Method for preparing blue dye by extracting tannin from dogwood and device used by method

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