CN110742909A - Method for carrying out biological fermentation by utilizing fresh traditional Chinese medicinal materials - Google Patents
Method for carrying out biological fermentation by utilizing fresh traditional Chinese medicinal materials Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8984—Dendrobium
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/225—Lactobacillus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/46—Streptococcus ; Enterococcus; Lactococcus
Abstract
The invention discloses a method for carrying out biological fermentation by utilizing fresh Chinese medicinal materials, which comprises the following steps: cleaning the fresh traditional Chinese medicinal materials by using purified water, and then airing the cleaned fresh traditional Chinese medicinal materials; feeding the dried fresh Chinese medicinal materials into a crusher for crushing to obtain bulk medicinal materials; sending the bulk medicinal materials into a container, adding ingredients and strains, and placing on a shelf for fermentation. According to the method for carrying out biological fermentation by using the fresh traditional Chinese medicinal materials, firstly, the drug effect of the traditional Chinese medicinal materials is improved, the toxic and side effects of the traditional Chinese medicinal materials are eliminated, the drug property of the traditional Chinese medicinal materials is improved, the dosage of the traditional Chinese medicinal materials is reduced, the utilization rate of the traditional Chinese medicinal materials is improved, the taste of the traditional Chinese medicinal materials is improved, secondly, macromolecular substances in the traditional Chinese medicinal materials can be converted into micromolecular substances, the absorption speed of a human body to the medicines is accelerated, the macromolecular substances can be directly absorbed by intestinal mucosa, the burden of the stomach, the liver and the kidney is.
Description
Technical Field
The invention relates to the field of medicinal materials, in particular to a method for carrying out biological fermentation by utilizing fresh Chinese medicinal materials.
Background
The quantity of a lot of rare wild traditional Chinese medicinal materials is very little, the demand of people for the traditional Chinese medicinal materials is not met, the drug effect of the traditional Chinese medicinal materials cannot be fully utilized when the traditional Chinese medicinal materials are used, a lot of precious resources are lost, the traditional Chinese medicinal materials are wasted, the traditional Chinese medicinal materials can destroy the optimal active ingredients of some fresh traditional Chinese medicinal materials in the links of production, processing, soaking and the like, the curative effect of the traditional Chinese medicinal materials is reduced, in addition, in the storage process, some chemical agents can be added for better corrosion prevention, moisture prevention and mildew prevention, the drug effect of the traditional Chinese medicinal materials can be reduced, and therefore, a method for carrying out biological fermentation by utilizing the fresh traditional Chinese medicinal materials is.
Disclosure of Invention
The invention mainly aims to provide a method for carrying out biological fermentation by utilizing fresh traditional Chinese medicinal materials, which can effectively solve the problems in the background technology.
In order to achieve the purpose, the invention adopts the technical scheme that:
a method for carrying out biological fermentation by using fresh Chinese medicinal materials comprises the following steps:
(1) cleaning the fresh traditional Chinese medicinal materials by using purified water, and then airing the cleaned fresh traditional Chinese medicinal materials;
(2) feeding the dried fresh Chinese medicinal materials into a crusher for crushing to obtain bulk medicinal materials;
(3) and sending the bulk medicinal materials into a container, adding ingredients and strains, and placing on a shelf for fermentation.
Preferably, in the step (1), the fresh Chinese medicinal materials refer to the Chinese medicinal materials with no mildew on the surface, no discoloration, no odor and no decay.
Preferably, in the step (1), the water temperature of purified water is 20-40 ℃ when fresh Chinese medicinal materials are cleaned, and the water content in the cleaned and dried Chinese medicinal materials is 8-12%.
Preferably, in the step (2), the size of the crushed bulk medicinal material is 0.1-5 cm.
Preferably, in the step (3), the ingredients are purified water, honey and propolis, and the strains are probiotics including but not limited to bifidobacterium, lactobacillus and streptococcus thermophilus.
Preferably, the ratio of the purified water to the honey to the fresh traditional Chinese medicinal materials to the propolis to the strain is 90:10:36:2: 1.
Preferably, in the step (3), the fermentation temperature of the fresh Chinese medicinal materials is 35-40 ℃, and the humidity during fermentation is 70-80%.
Compared with the prior art, the method for carrying out biological fermentation by utilizing fresh Chinese medicinal materials has the following beneficial effects:
1. the method has the advantages that the fresh traditional Chinese medicinal materials are fermented by adopting various microorganisms, so that the drug effect of the traditional Chinese medicinal materials is improved, the toxic and side effects in the traditional Chinese medicinal materials are eliminated, the drug property of the traditional Chinese medicines is improved, the dosage of the traditional Chinese medicinal materials is reduced, the utilization rate of the traditional Chinese medicines is improved, and the taste of the traditional Chinese medicines is improved;
2. the traditional Chinese medicine is predigested by adopting various probiotics, the medicinal materials are decomposed and converted, macromolecular substances in the medicinal materials are converted into small molecular substances which can be directly absorbed by a human body, the absorption speed of the human body to the medicine can be accelerated, and active ingredients in the medicinal materials can be directly absorbed by intestinal mucosa without being absorbed and transmitted by stomach, liver and kidney, so that the burden of the stomach, the liver and the kidney is reduced, the curative effect is shorter, the medicine effect display speed is higher, and the content of the medicine taken is 20 times less than that of the medicine normally used;
3. the method for biological fermentation by using the fresh Chinese medicinal materials is simple, convenient to operate and better in use effect compared with the traditional method.
Drawings
FIG. 1 is an overall flow chart of a method for carrying out biological fermentation by using fresh Chinese medicinal materials according to the present invention.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
Example 1
(1) Cleaning fresh Chinese medicinal materials by using purified water, and then drying the cleaned fresh Chinese medicinal materials, wherein the fresh Chinese medicinal materials refer to the Chinese medicinal materials without mildew, discoloration, peculiar smell and decay on the surfaces of the Chinese medicinal materials, the water temperature of the purified water is 25 ℃ when the fresh Chinese medicinal materials are cleaned, and the water content of the dried Chinese medicinal materials is 10%;
(2) feeding the dried fresh traditional Chinese medicinal materials into a crusher for crushing to obtain a bulk medicinal material, wherein the size of the crushed bulk medicinal material is 0.5 cm;
(3) the bulk medicinal materials are fed into a container, ingredients and strains are added, the container is placed on a shelf for fermentation, the ingredients adopt purified water, honey and propolis, the strains adopt probiotics, the probiotics include but are not limited to bifidobacteria, lactobacillus and streptococcus thermophilus, the ratio of the purified water, the honey, the fresh traditional Chinese medicinal materials, the propolis and the strains is 90:10:36:2:1, the fermentation temperature of the fresh traditional Chinese medicinal materials is 37 ℃, the humidity during fermentation is 72%, the container adopts a food-grade plastic tank with the capacity of 2L/73.9g, the specification of the shelf is 2000CM x 60CM x 40CM, and the shelf is divided into 5 layers with equal space.
Example 2
(1) Firstly, cleaning the dendrobium huoshanense by using purified water, and then drying the cleaned dendrobium huoshanense, wherein the fresh dendrobium huoshanense refers to the dendrobium huoshanense with no mildew on the surface of the medicinal material, no color change, no peculiar smell and no rot, the water temperature of the purified water is 25 ℃ when the dendrobium huoshanense is cleaned, and the water content in the dendrobium huoshanense after the cleaned medicinal material is dried is 10%;
(2) feeding the dried dendrobium huoshanense into a crusher to be crushed to obtain blocky dendrobium huoshanense, wherein the size of the crushed blocky medicinal material is 0.5 cm;
(3) the method comprises the steps of feeding the massive dendrobium huoshanense into a container, adding ingredients and strains, placing the container on a shelf for fermentation, wherein the ingredients adopt purified water, honey and propolis, the strains adopt probiotics, the probiotics include but are not limited to bifidobacteria, lactobacillus and streptococcus thermophilus, the proportion of the purified water, the honey, the dendrobium huoshanense, the propolis and the strains is 90:10:36:2:1, the fermentation temperature of fresh Chinese medicinal materials is 37 ℃, the humidity during fermentation is 72%, the container adopts a food-grade plastic tank with the capacity of 2L/73.9g, the specification of the shelf is 2000CM multiplied by 60 multiplied by 40CM, and the shelf is divided into 5 layers with equal space.
The prepared dendrobium candidum fermentation liquor is filled into a spray dropping bottle to directly spray and drop nasal cavities or oral cavities, 1ML is performed each time, and 3-5 times are sprayed in one day, so that rhinitis and pharyngitis can be quickly treated.
Example 3
(1) Firstly, cleaning the dendrobium huoshanense by using purified water, and then drying the cleaned dendrobium huoshanense, wherein the fresh dendrobium huoshanense refers to the dendrobium huoshanense with no mildew on the surface of the medicinal material, no color change, no peculiar smell and no rot, the water temperature of the purified water is 25 ℃ when the dendrobium huoshanense is cleaned, and the water content in the dendrobium huoshanense after the cleaned medicinal material is dried is 10%;
(2) feeding the dried dendrobium huoshanense into a crusher to be crushed to obtain blocky dendrobium huoshanense, wherein the size of the crushed blocky medicinal material is 0.5 cm;
(3) the method comprises the steps of feeding the massive dendrobium huoshanense into a container, adding ingredients and strains, placing the container on a shelf for fermentation, wherein the ingredients adopt purified water, honey and propolis, the strains adopt probiotics, the probiotics include but are not limited to bifidobacteria, lactobacillus and streptococcus thermophilus, the proportion of the purified water, the honey, the dendrobium huoshanense, the propolis and the strains is 90:10:36:2:1, the fermentation temperature of fresh Chinese medicinal materials is 37 ℃, the humidity during fermentation is 72%, the container adopts a food-grade plastic tank with the capacity of 2L/73.9g, the specification of the shelf is 2000CM multiplied by 60 multiplied by 40CM, and the shelf is divided into 5 layers with equal space.
The prepared dendrobium huoshanense fermentation liquor is filled into a spray bottle and directly permeates 1ML of the fermented dendrobium huoshanense fermentation liquor into ear cavities in a dripping mode, the dendrobium huoshanense fermentation liquor is poured out after 5-10 minutes of ear middle ear bath, and the tinnitus can be quickly treated by spraying for 3-5 times a day.
The method for performing biological fermentation by using the fresh traditional Chinese medicinal materials has the advantages that when the method is used, the fresh traditional Chinese medicinal materials are fermented by adopting multiple probiotics, so that the drug effect of the traditional Chinese medicinal materials is improved, the toxic and side effects in the traditional Chinese medicinal materials are eliminated, the drug property of the traditional Chinese medicines is improved, the dosage of the traditional Chinese medicinal materials is reduced, the utilization rate of the traditional Chinese medicines is improved, and the taste of the traditional Chinese medicines is improved;
the traditional Chinese medicine is predigested by adopting various probiotics, the medicinal materials are decomposed and converted, macromolecular substances in the medicinal materials are converted into small molecular substances which can be directly absorbed by a human body, the absorption speed of the human body to the medicine can be accelerated, and active ingredients in the medicinal materials can be directly absorbed by intestinal mucosa without being absorbed and transmitted by stomach, liver and kidney, so that the burden of the stomach, the liver and the kidney is reduced, the curative effect is shorter, the medicine effect display speed is higher, and the content of the medicine taken is 20 times less than that of the medicine normally used;
the method for biological fermentation by using the fresh Chinese medicinal materials is simple, convenient to operate and better in use effect compared with the traditional method.
The foregoing shows and describes the general principles and broad features of the present invention and advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (8)
1. A method for carrying out biological fermentation by using fresh Chinese medicinal materials comprises the following steps:
(1) cleaning the fresh traditional Chinese medicinal materials by using purified water, and then airing the cleaned fresh traditional Chinese medicinal materials;
(2) feeding the dried fresh Chinese medicinal materials into a crusher for crushing to obtain bulk medicinal materials;
(3) and sending the bulk medicinal materials into a container, adding ingredients and strains, and placing on a shelf for fermentation.
2. The method for biological fermentation by using fresh Chinese medicinal materials as claimed in claim 1, wherein the method comprises the following steps: in the step (1), the fresh Chinese medicinal materials refer to the medicinal materials without mildew, discoloration, odor and decay on the surface.
3. The method for biological fermentation by using fresh Chinese medicinal materials as claimed in claim 1, wherein the method comprises the following steps: in the step (1), the water temperature of purified water is 20-40 ℃ when fresh Chinese medicinal materials are cleaned, and the water content in the cleaned Chinese medicinal materials is 8-12% after the Chinese medicinal materials are dried.
4. The method for biological fermentation by using fresh traditional Chinese medicinal materials as claimed in claim 1, wherein in the step (2), the size of the crushed bulk medicinal materials is 0.1-5 cm.
5. The method for biological fermentation by using fresh Chinese medicinal materials as claimed in claim 1, wherein the method comprises the following steps: in the step (3), the ingredients are purified water, honey and propolis, and the strains are probiotics including but not limited to bifidobacteria, lactobacilli and streptococcus thermophilus.
6. The method for biological fermentation by using fresh Chinese medicinal materials as claimed in claim 5, wherein the method comprises the following steps: the ratio of the purified water to the honey to the fresh traditional Chinese medicinal materials to the propolis to the strain is 90:10:36:2: 1.
7. The method for biological fermentation by using fresh Chinese medicinal materials as claimed in claim 1, wherein the method comprises the following steps: in the step (3), the fermentation temperature of the fresh Chinese medicinal materials is 35-40 ℃, and the humidity during fermentation is 70-80%.
8. The method for biological fermentation by using fresh Chinese medicinal materials as claimed in claim 1, wherein the method comprises the following steps: in the step (3), the container is made of food-grade plastic cans with the capacity of 2L/73.9g, the specification of the goods shelf is 2000CM multiplied by 60CM multiplied by 40CM, and the goods shelf is divided into 5 layers with equal space.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911039405.5A CN110742909A (en) | 2019-10-29 | 2019-10-29 | Method for carrying out biological fermentation by utilizing fresh traditional Chinese medicinal materials |
| AU2020103099A AU2020103099A4 (en) | 2019-10-29 | 2020-10-29 | Method for biological fermentation using fresh chinese medicinal material |
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| CN201911039405.5A CN110742909A (en) | 2019-10-29 | 2019-10-29 | Method for carrying out biological fermentation by utilizing fresh traditional Chinese medicinal materials |
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103908475A (en) * | 2014-03-26 | 2014-07-09 | 深圳市新华南方生物科技股份有限公司 | Traditional Chinese medicine preparation method |
| CN104940644A (en) * | 2015-06-30 | 2015-09-30 | 广东罗特制药有限公司 | Method for fermenting dendrobium officinale employing lactic acid bacteria, as well as fermented product and application of dendrobium officinale |
| CN104957623A (en) * | 2015-07-09 | 2015-10-07 | 丁政然 | Preparation method of ginseng composite fruit-vegetable enzyme and a product |
| CN106074640A (en) * | 2016-06-20 | 2016-11-09 | 陈云海 | A kind of fermented tcm |
| CN106360683A (en) * | 2016-08-29 | 2017-02-01 | 广西壮族自治区农业科学院农产品加工研究所 | Dendrobium officinale and banana compound probiotic fermentation products and method thereof |
| CN107258976A (en) * | 2017-06-24 | 2017-10-20 | 赵龙富 | Probiotics black tea and preparation method thereof |
| CN107647392A (en) * | 2017-09-27 | 2018-02-02 | 霍山县长冲中药材开发有限公司 | A kind of fermentation noble dendrobium stem distillate of fast purification cholesterol |
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2019
- 2019-10-29 CN CN201911039405.5A patent/CN110742909A/en active Pending
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2020
- 2020-10-29 AU AU2020103099A patent/AU2020103099A4/en not_active Ceased
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103908475A (en) * | 2014-03-26 | 2014-07-09 | 深圳市新华南方生物科技股份有限公司 | Traditional Chinese medicine preparation method |
| CN104940644A (en) * | 2015-06-30 | 2015-09-30 | 广东罗特制药有限公司 | Method for fermenting dendrobium officinale employing lactic acid bacteria, as well as fermented product and application of dendrobium officinale |
| CN104957623A (en) * | 2015-07-09 | 2015-10-07 | 丁政然 | Preparation method of ginseng composite fruit-vegetable enzyme and a product |
| CN106074640A (en) * | 2016-06-20 | 2016-11-09 | 陈云海 | A kind of fermented tcm |
| CN106360683A (en) * | 2016-08-29 | 2017-02-01 | 广西壮族自治区农业科学院农产品加工研究所 | Dendrobium officinale and banana compound probiotic fermentation products and method thereof |
| CN107258976A (en) * | 2017-06-24 | 2017-10-20 | 赵龙富 | Probiotics black tea and preparation method thereof |
| CN107647392A (en) * | 2017-09-27 | 2018-02-02 | 霍山县长冲中药材开发有限公司 | A kind of fermentation noble dendrobium stem distillate of fast purification cholesterol |
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