CN110741081B - 肿瘤选择性tata盒和caat盒突变体 - Google Patents

肿瘤选择性tata盒和caat盒突变体 Download PDF

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CN110741081B
CN110741081B CN201880021788.0A CN201880021788A CN110741081B CN 110741081 B CN110741081 B CN 110741081B CN 201880021788 A CN201880021788 A CN 201880021788A CN 110741081 B CN110741081 B CN 110741081B
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cancer
nucleotides
recombinant adenovirus
cells
deletion
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CN110741081A (zh
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托尼·R·雷德
布莱恩·T·奥兰斯基
法拉·海德兰
克里斯托弗·拉森
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Epicentrx Inc
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CN201880021788.0A 2017-01-30 2018-01-30 肿瘤选择性tata盒和caat盒突变体 Active CN110741081B (zh)

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US201762452075P 2017-01-30 2017-01-30
US62/452,075 2017-01-30
PCT/US2018/016025 WO2018140970A1 (en) 2017-01-30 2018-01-30 Tumor selective tata-box and caat-box mutants

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KR (2) KR102880548B1 (enExample)
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SG11201507393TA (en) 2013-03-14 2015-10-29 Salk Inst For Biological Studi Oncolytic adenovirus compositions
PL3198009T3 (pl) 2014-09-24 2022-01-24 Salk Institute For Biological Studies Onkolityczne wirusy nowotworowe i sposoby zastosowania
JP7054527B2 (ja) 2016-02-23 2022-04-14 ソーク インスティテュート フォー バイオロジカル スタディーズ アデノウイルスの複製動態を測定するための高スループットアッセイ
JP7015551B2 (ja) 2016-02-23 2022-02-15 ソーク インスティテュート フォー バイオロジカル スタディーズ ウイルス動態への影響を最小限にするための治療用アデノウイルスにおける外因性遺伝子発現
WO2018111767A1 (en) 2016-12-12 2018-06-21 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
CA3059605A1 (en) 2017-04-10 2018-10-18 Epicentrx, Inc. Method for producing recombinant virus
JP7430395B2 (ja) 2018-04-09 2024-02-13 ソーク インスティテュート フォー バイオロジカル スタディーズ 複製特質が増強された腫瘍溶解性アデノウイルス組成物
WO2024015876A1 (en) 2022-07-13 2024-01-18 Epicentrx, Inc. Adenoviral vectors encapsulated in cationic liposomes, and preparation and use thereof

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CN110741081A (zh) 2020-01-31
JP7242534B2 (ja) 2023-03-20
KR20230164231A (ko) 2023-12-01
AU2018212017B2 (en) 2024-11-28
BR112019015514A2 (pt) 2020-04-07
KR20190128633A (ko) 2019-11-18
EP3573632B1 (en) 2024-08-07
MX2019008922A (es) 2020-01-20
US20190352669A1 (en) 2019-11-21
IL268289A (en) 2019-09-26
AU2018212017A1 (en) 2019-08-15
EP3573632A1 (en) 2019-12-04
US20250388930A1 (en) 2025-12-25
KR102607220B1 (ko) 2023-12-01
KR102880548B1 (ko) 2025-11-05
JP2020505046A (ja) 2020-02-20
IL268289B2 (en) 2025-09-01
EP3573632C0 (en) 2024-08-07
EP3573632A4 (en) 2020-09-23
IL268289B1 (en) 2025-05-01
SG11201906976YA (en) 2019-08-27
CA3052086A1 (en) 2018-08-02
EA201991806A1 (ru) 2020-02-13
WO2018140970A1 (en) 2018-08-02

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