CN110711233A - Traditional Chinese medicine composition, medicinal liquor and decoction for conditioning sub-health - Google Patents

Traditional Chinese medicine composition, medicinal liquor and decoction for conditioning sub-health Download PDF

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CN110711233A
CN110711233A CN201911067324.6A CN201911067324A CN110711233A CN 110711233 A CN110711233 A CN 110711233A CN 201911067324 A CN201911067324 A CN 201911067324A CN 110711233 A CN110711233 A CN 110711233A
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樊国欣
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Diguo Biotechnology Co Ltd
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234Cnidium (snowparsley)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/746Morinda
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
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    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention provides a traditional Chinese medicine composition, a medicinal liquor and a decoction for conditioning sub-health, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition for conditioning sub-health comprises the following components: 30-60 parts of Chinese yam, 30-60 parts of kudzu root, 30-60 parts of rhizoma polygonati, 30-60 parts of medlar, 30-60 parts of epimedium, 30-60 parts of astragalus membranaceus, 30-60 parts of raspberry, 30-60 parts of morinda officinalis, 30-60 parts of fructus cnidii, 30-60 parts of cinnamon, 30-60 parts of oyster and 30-60 parts of clove. The invention adopts the compatibility of medicinal and edible traditional Chinese medicinal materials according to the monarch, minister, assistant and guide principle, and the interaction between monarch, minister, assistant and guide medicines can nourish yin and suppress yang, clear up in vivo waste toxin, discharge in vivo wind, cold, dampness and summer heat toxin, tonify yang qi, dredge channels and collaterals, invigorate qi and generate blood, balance yin and yang, nourish and coordinate five viscera and six fu organs, thereby effectively absorbing nutrition, balancing yin and yang of human body, storing vital qi in the human body, recovering the young state of human body, improving the sub-health state, recovering the health of sub-health people, and improving the quality of life and health.

Description

Traditional Chinese medicine composition, medicinal liquor and decoction for conditioning sub-health
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition, a medicinal liquor and a decoction for conditioning sub-health.
Background
Sub-health of the human body is an unhealthy state, called sub-state for short. The etiology of the disease is related to long-term mental stress, excessive psychological stress and unbalanced emotion. According to authoritative survey of the world health organization, 75% of people in modern life have different degrees of sub-health status. It was investigated that 85% of these sub-healthy populations are due to poor social and psychological stress, and the heart is the leading cause. The investigation shows that the incidence of sub-health of middle-aged people after the age of 40 is steeply increased because the middle-aged people are under the dual social and family pressure. It is estimated that 2/3 people will have a chance of developing cardiovascular disease after several years, and 10% of people will develop coronary heart disease after several years in a hurry personality type a behavior population. Researches find that the phenomenon of psychological disorder is formed with the acceleration of social rhythm, the gradual complexity of interpersonal relationship and poor social adaptability for a long time. As a result of fine research, the more the social elite level, the more serious the sub-health problem, and the rapidly rising trend.
Sub-health is a new general idea, and comprises a plurality of stages connected in series, wherein, the stages closely adjacent to health can be called as mild physical and mental disorder, which is often characterized by fatigue, insomnia, headache, dizziness, poor appetite and emotional instability, the stages often do not attract people's attention, and the continuous physical and mental imbalance develops in succession, and the people enter the subclinical stage of sub-health, and can show three types of decline: the vitality decline, the reaction ability decline, the adaptability decline, it is found that the patients in the affluent level of the city can have the tendency of three highs and one low, the hyperlipemia, the hyperglycemia, the high blood viscosity and the immunologic function which are close to the critical level are low, and most women patients show the menstrual disorder phenomenon. Sub-health these populations have 10% of their pre-clinical states ranging between subclinical and disease, which strictly speaking are not sub-health.
Sub-health is a new research field of the 21 st century and world medicine, and draws wide attention to medicine as a new medical difficulty. Foreign and foreign medicine have been discussed as a century-onset, and western medicine is called "gray state" or "stress response syndrome". Modern medicine in China is called as 'third state' and 'intermediate state'. That is, sub-health has a tendency to metastasize on both sides under certain internal and external conditions, and it can restore health and cause diseases. Thus, preventive medicine reminds the nation of people to adjust sub-health status in time. The health is recovered as early as possible, and the quality of life health is improved.
Sub-health is regarded as a medical difficulty in the new century, and one of the important meanings of sub-health is that sub-health has a large latent life crisis, and it is estimated that 80% of sub-health people usually suffer from cardiovascular and cerebrovascular diseases in about 8-12 years once they enter a latent clinical state. The second difficulty is the problem of difficult diagnosis, and when the sub-health is not considered by western medicine, and no positive result is found in instrument examination, the problem of difficult diagnosis is generated. The third difficulty is that the treatment is difficult, and the treatment is ineligible because the diagnosis cannot be made clearly.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for conditioning sub-health, which can improve the sub-health state, recover the health of sub-health people, improve the quality of life and health and prolong the life.
The second purpose of the invention is to provide a medicinal liquor prepared by adopting the traditional Chinese medicine composition.
The third purpose of the invention is to provide a decoction prepared from the traditional Chinese medicine composition.
In order to achieve the above purpose, the technical scheme adopted by the composition for conditioning sub-health of the invention is as follows: the traditional Chinese medicine composition for conditioning sub-health comprises the following components in parts by weight: 30-60 parts of Chinese yam, 30-60 parts of kudzu root, 30-60 parts of rhizoma polygonati, 30-60 parts of medlar, 30-60 parts of epimedium, 30-60 parts of astragalus membranaceus, 30-60 parts of raspberry, 30-60 parts of morinda officinalis, 30-60 parts of fructus cnidii, 30-60 parts of cinnamon, 30-60 parts of oyster and 30-60 parts of clove.
Preferably, the traditional Chinese medicine composition for conditioning sub-health is characterized by comprising the following components in parts by weight: 55 parts of Chinese yam, 50 parts of kudzu root, 52 parts of rhizoma polygonati, 45 parts of medlar, 40 parts of epimedium herb, 42 parts of astragalus, 34 parts of raspberry, 38 parts of morinda officinalis, 30 parts of fructus cnidii, 32 parts of cinnamon, 30 parts of oyster and 30 parts of clove.
The traditional Chinese medicine composition for conditioning sub-health can be prepared into conventional dosage forms in the field of traditional Chinese medicines, such as decoction, wine and other medically acceptable dosage forms for administration.
A medicinal liquor prepared from the traditional Chinese medicine composition is prepared by the following steps:
(1) weighing the components in parts by weight, mixing, and mixing according to the weight ratio of 1: adding water into the mixed components in a material-water ratio of 10-15, decocting for 2-3 times, each time for 1-1.5 hours, combining water decoctions obtained each time, and freeze-drying to obtain traditional Chinese medicine freeze-dried powder;
(2) inoculating the traditional Chinese medicine freeze-dried powder prepared in the step (1) into a mixed bacterial liquid, wherein the weight ratio of the traditional Chinese medicine freeze-dried powder to the mixed liquid is 1: 10-20, and the mixed bacterial liquid comprises: 2 multiplied by 108cfu/ml of bacillus subtilis, 3 multiplied by 108cfu/ml of lactobacillus casei, 2 multiplied by 108cfu/ml of lactobacillus plantarum, 1 multiplied by 108cfu/ml of bifidobacterium breve and 1 multiplied by 108cfu/ml of microzyme, and carrying out closed fermentation for 30-50 h to prepare a fermentation liquid;
(3) and (2) filtering and filling the fermentation liquor prepared in the step (1) to obtain the wine.
A decoction prepared from the traditional Chinese medicine composition is prepared by the following steps: weighing the components in parts by weight, mixing, and mixing according to the weight ratio of 1: adding water into the mixed components in a material-water ratio of 10-15, decocting for 2-3 times, each time for 1-1.5 hours, and combining water decoction obtained each time to obtain decoction.
In the traditional Chinese medicine composition for conditioning sub-health, the effects and the functions of the components are as follows:
wolfberry (wolfberry): sweet in flavor, neutral in nature, entering liver and kidney meridians. Nourishing liver and kidney, replenishing vital essence and improving eyesight. Can be used for treating asthenia, soreness of waist and knees, vertigo, tinnitus, internal heat, diabetes, blood deficiency, sallow complexion, and blurred vision. Wolfberry fruit contains rich carotene, betaine, vitamins, Ca, Fe and other essential nutrients, and thus has the function of improving eyesight, and is also called eyesight. Modern pharmacological research finds that: the white blood cell count of the mouse can be increased by drenching 0.5 ml of 10% medlar decoction every day for 10 consecutive days; also has protective effect on the leucopoiesis inhibition effect caused by the cyclophosphamide. Wolfberry fruit is often used by physicians of all generations to treat blurred vision and night blindness caused by liver-blood deficiency and kidney-yin deficiency. The famous prescription, Qijudihuang Wan, uses Goji Qi Zi as the main medicine.
Astragalus root: huang Qi is sweet in flavor and slightly warm in nature. It enters lung, spleen, liver and kidney meridians. Tonify qi, strengthen superficies, induce diuresis, expel pus, heal wound and promote tissue regeneration. Can be used for treating qi deficiency, asthenia, anorexia, loose stool, collapse of middle-warmer energy, chronic diarrhea, rectocele, hematochezia, metrorrhagia, superficial deficiency, spontaneous perspiration, carbuncle, cellulitis, ulcer, blood deficiency, sallow complexion, internal heat, and diabetes.
Raspberry: warm in nature, sweet in flavor and sour. It enters kidney and bladder meridians. Tonifying kidney, arresting spontaneous emission, and reducing urination.
Chinese yam: is tuber of Dioscorea opposita Thunb of Dioscorea of Dioscoreaceae; contains effective components such as diosgenin, dopamine, dioscin hydrochloride, allantoin, various amino acids, and microelements; sweet and neutral in nature, they enter spleen, lung and kidney meridians. Has effects in invigorating spleen, nourishing lung, reinforcing kidney, and replenishing vital essence; it can be used for treating diarrhea due to spleen deficiency, anorexia, edema, cough and asthma due to lung deficiency, diabetes, spermatorrhea, leukorrhagia, and frequent micturition due to kidney deficiency; it is externally used for abscess and scrofula. Modern pharmacological studies show that the Chinese yam has the effects of reducing blood sugar, promoting the functions of the digestive system, improving the immune function, resisting oxidation activity, reducing fat and the like.
Kudzu root: sweet in flavor, pungent and cool in nature, and entering spleen, stomach and lung meridians. Has the functions of expelling pathogenic factors from muscles, allaying fever, promoting the production of body fluid, quenching thirst, invigorating yang, relieving diarrhea, clearing and activating the channels and collaterals, and the like. It can be used for treating fever due to exogenous pathogens, thirst due to fever, and alcoholic intoxication. Modern researches show that the kudzuvine root contains 12 percent of flavonoid compounds, such as puerarin, soybean flavonoid glycoside, peanut essence and other nutrient components, and also contains protein, amino acid, sugar and minerals such as iron, calcium, copper, selenium and the like which are necessary for human bodies, and has the reputation of Asian ginseng. As early as in Shang Han Lun of Zhang Zhongjing, a famous prescription of Kudzuvine root decoction is still an important exterior syndrome relieving prescription. In Ben Cao Zheng Yi (Chinese materia medica remedy), Ku Gen is the best to develop the qi of spleen and stomach clearing yang. Has effects in regulating human body function, improving body condition, promoting metabolism, and enhancing liver function.
Radix morindae officinalis: pungent and sweet in flavor and slightly warm in nature. It enters kidney meridian. Tonify kidney yang, strengthen tendons and bones, dispel wind-damp. Can be used for treating sexual impotence, spermatorrhea, infertility due to cold womb, menoxenia, cold pain of lower abdomen, rheumatic arthralgia, and flaccidity of tendons and bones.
Rhizoma polygonati: is prepared from rhizome of Polygonatum sibiricum Red, Polygonatum cyrtonema Hua and Polygonatum kingianum of Polygonatum of Liliaceae; contains multiple active ingredients such as furostanol type saponin, spirostanol type saponin, and rhizoma Polygonati polysaccharide; rhizoma Polygonati is sweet in nature and flavor, and flat, and enters spleen, lung and kidney meridians; has effects in nourishing yin, moistening lung, invigorating spleen, invigorating qi, replenishing kidney essence, and replenishing essence; mainly treats yin deficiency cough, lung dryness cough, spleen deficiency and hypodynamia, poor appetite and dry mouth, diabetes, kidney deficiency, soreness and weakness of waist and knees, tinnitus and dark eyes, early white beard and hair, body deficiency and emaciation, leprosy tinea and the like; modern pharmacology proves that rhizoma polygonati has influence on cardiovascular system, blood sugar, immunologic function and cyclic nucleotide content, and also has the functions of reducing blood fat, delaying senility, improving learning ability and realizing memory reproduction.
Clove: pungent in flavor and warm in nature, and enter spleen, stomach and kidney meridians; can warm the middle warmer, lower adverse qi, and warm the kidney; can be used for treating singultus, emesis, regurgitation, dysentery, abdominal psychroalgia, hernia, and tinea; modern pharmacology proves that the clove has the effects of resisting inflammation, easing pain, inhibiting microorganisms, relieving fever, resisting blood coagulation, resisting oxidation, resisting anoxia, resisting mutagenesis and the like.
Herba epimedii: warm in nature, pungent and sweet in flavor; entering liver and kidney meridians; has effects in invigorating kidney, supporting yang, expelling pathogenic wind, removing dampness, and relieving cough and asthma. Modern pharmacological research shows that the main active ingredients of the compound are icariin, demethylicariin and the like, and the compound has the following main effects: lowering blood pressure, improving microcirculation and lowering blood sugar; can promote and bidirectionally regulate immune function; the compound has the functions of bacteriostasis, anti-inflammation, interferon induction and obvious inhibition on poliovirus; promoting bone growth, preventing calcium loss, and preventing osteoporosis; has the prospect of anti-aging, anti-oxidation and anti-tumor.
Fructus cnidii: pungent, bitter and warm in nature; it enters liver and kidney meridians. Has effects in promoting cardiovascular system, regulating endocrine and reproductive system, resisting microorganism, relieving itching, resisting allergy, preventing and treating osteoporosis, resisting mutagenesis, and resisting tumor; warming kidney and strengthening yang, killing parasites due to dryness-heat, dispelling wind and relieving itching; can be used for treating sexual impotence, infertility due to cold womb, arthralgia due to dampness, lumbago, leukorrhagia due to cold-dampness, pudendal pruritus, rheumatalgia, eczema, and scabies.
Cinnamon: is dry bark and branch bark of cortex Cinnamomi of Lauraceae and Lauraceae; it contains volatile oils such as cinnamaldehyde, cinnamaldehyde acetate, ethyl cinnamate, benzyl benzoate, benzaldehyde, coumarin, calamene, protocatechuic acid, catechin derivatives such as L-epicatechin, cinnamyl tannin A2-A4, flavonoids and diterpenes, and optionally canescentin, dehydrated canceryl alcohol, racemic-eugenol, cinnamyl glycoside, and GUIPI polysaccharide AX; pungent, sweet and hot in nature, entering kidney, spleen, heart and liver meridians; has effects in tonifying fire, supporting yang, dispelling cold, relieving pain, warming channels, and dredging collaterals; mainly treats kidney yang deficiency, intolerance of cold and cold limbs due to decline of the fire of the gate of life, soreness and weakness of waist and knees, dysuria or frequent micturition, shortness of breath, dyspnea, edema and oliguria, decline of the fire of the gate of life, failure of fire to return to the source, wearing yang, yang deficiency, upper heat and lower cold, flushed face and cold feet, dizziness and tinnitus, aphthous stomatitis and tongue erosion, deficiency cold of spleen and kidney, abdominal cold pain, loose stool due to eating and diarrhea, lumbago due to kidney deficiency, cold-damp arthralgia, cold hernia pain, infertility due to cold in uterus, dysmenorrhea and amenorrhea, postpartum stasis and abdominal pain, dorsal furuncle and multiple abscess and abscess, or no ulcer due to deficiency cold and pus, or no astringency after ulcer; modern pharmacology proves that cinnamon has the effects of resisting ulcer, resisting platelet aggregation, resisting inflammation, resisting bacteria, resisting tumors, delaying senescence and the like.
Oyster shell: it is salty in nature and slightly cold in nature. It enters liver, gallbladder and kidney meridians. The efficacy of oyster is mainly: astringe yin, subdue yang, check sweating, astringe essence, resolve phlegm and soften hard masses. Belongs to the liver-calming and wind-extinguishing herbs, has the effects of tranquilizing the mind, suppressing yang hyperactivity, tonifying yin, softening hardness and dissipating stagnation. It can be used for treating uneasiness, palpitation, insomnia, hyperactivity of liver-yang, dizziness, and blurred vision. For yin deficiency and yang hyperactivity, dizziness, vertigo, restlessness and tinnitus, it is often combined with Long Gu, Gui Jia and Bai Shao, for instance, Zheng gan Xi Feng Tang (Zhong Can xi Lu in medicine). The oyster has the functions of strengthening liver and detoxifying, and the liver glycogen of the oyster exists in the liver and muscle storing energy, is closely related to the division and regeneration of cells and the activation of red blood cells, and can improve liver function, recover fatigue and enhance physical strength. The taurine contained in Concha Ostreae can promote bile secretion, eliminate neutral fat accumulated in liver, and improve liver detoxification effect. The oyster also contains calcium carbonate, calcium phosphate and calcium sulfate, and contains microelements such as copper, iron, zinc, manganese, strontium and chromium, and various amino acids.
The invention has the beneficial effects that: the invention adopts 12 Chinese medicinal materials of medlar, astragalus, raspberry, yam, kudzu root, morinda officinalis, sealwort, clove, epimedium herb, common cnidium fruit, cassia bark and oyster which are homologous in medicine and food, and adopts the compatibility formula according to the principle of monarch, minister, assistant and guide, the yam, kudzu root and sealwort are used as monarch drugs, the medlar, epimedium herb and astragalus are used as minister drugs, the raspberry and morinda officinalis are used as assistant drugs, the common cnidium fruit, cinnamon, oyster and clove are used as conductant drugs, the interaction among the monarch, assistant and guide drugs is realized, the effects of nourishing yin and suppressing yang are realized, the in-vivo rubbish toxin is cleared, the in-vivo wind cold and damp summer-heat toxin is discharged, the yang qi is supplemented, the channels and collaterals are dredged, the qi and the blood are replenished, the yin and yang are balanced, the young state of the human body is restored, the sub-health state is improved, the sub-health people are restored, The sub-health population with premature senility, insufficient essence, energy and spirit and the like caused by irregular diet, excessive couple life, excessive pressure of work and life and the like has important practical significance.
Detailed Description
The present invention will be further described with reference to the following examples.
Example 1
The traditional Chinese medicine composition for improving sub-health of the embodiment comprises the following components in parts by weight: 55 parts of Chinese yam, 50 parts of kudzu root, 52 parts of rhizoma polygonati, 45 parts of medlar, 40 parts of epimedium herb, 42 parts of astragalus, 34 parts of raspberry, 38 parts of morinda officinalis, 30 parts of fructus cnidii, 32 parts of cinnamon, 30 parts of oyster and 30 parts of clove.
The wine prepared by the traditional Chinese medicine composition is prepared by the following steps:
(1) weighing the components in parts by weight, mixing, and mixing according to the weight ratio of 1: 12, adding water into the mixed components in the ratio of material to water, decocting for 2 times, each time for 1.2h, combining the water decoctions obtained each time, and freeze-drying to obtain Chinese medicinal lyophilized powder;
(2) inoculating the traditional Chinese medicine freeze-dried powder prepared in the step (1) into a mixed bacterial liquid, wherein the weight ratio of the traditional Chinese medicine freeze-dried powder to the mixed liquid is 1:15, and the mixed bacterial liquid comprises: bacillus subtilis 2 x 108cfu/ml, lactobacillus casei 3 x 108cfu/ml, lactobacillus plantarum 2 x 108cfu/ml, bifidobacterium breve 1 x 108cfu/ml, microzyme 1 x 108cfu/ml, and fermenting in a sealed environment for 40h to prepare a fermentation liquid;
(3) and (2) filtering and filling the fermentation liquor prepared in the step (1) to obtain the wine.
The decoction prepared from the traditional Chinese medicine composition in the embodiment is prepared by the following steps: weighing the components in parts by weight according to the parts by weight, mixing, and mixing according to the weight ratio of 1: 12, adding water into the mixed components, decocting for 2 times (each time for 1.2 h), and mixing the water decoctions to obtain decoction.
Example 2
The traditional Chinese medicine composition for improving sub-health of the embodiment comprises the following components in parts by weight: 60 parts of Chinese yam, 30 parts of kudzu root, 60 parts of rhizoma polygonati, 30 parts of medlar, 60 parts of epimedium herb, 30 parts of astragalus, 60 parts of raspberry, 30 parts of morinda officinalis, 60 parts of common cnidium fruit, 30 parts of cinnamon, 60 parts of oyster and 30 parts of clove.
The wine prepared by the traditional Chinese medicine composition is prepared by the following steps:
(1) weighing the components in parts by weight, mixing, and mixing according to the weight ratio of 1:10, adding water into the mixed components in a material-water ratio, decocting for 3 times, each time for 1.5 hours, combining water decoctions obtained each time, and freeze-drying to obtain Chinese medicinal freeze-dried powder;
(2) inoculating the traditional Chinese medicine freeze-dried powder prepared in the step (1) into a mixed bacterial liquid, wherein the weight ratio of the traditional Chinese medicine freeze-dried powder to the mixed liquid is 1:10, and the mixed bacterial liquid comprises: 2 multiplied by 108cfu/ml of bacillus subtilis, 3 multiplied by 108cfu/ml of lactobacillus casei, 2 multiplied by 108cfu/ml of lactobacillus plantarum, 1 multiplied by 108cfu/ml of bifidobacterium breve and 1 multiplied by 108cfu/ml of microzyme, and carrying out closed fermentation for 30h to prepare a fermentation liquid;
(3) and (2) filtering and filling the fermentation liquor prepared in the step (1) to obtain the wine.
The decoction prepared from the traditional Chinese medicine composition in the embodiment is prepared by the following steps: weighing the components in parts by weight according to the parts by weight, mixing, and mixing according to the weight ratio of 1:10, adding water into the mixed components, decocting for 3 times (each time for 1.5 h), and mixing the water decoctions to obtain decoction.
Example 3
The traditional Chinese medicine composition for improving sub-health of the embodiment comprises the following components in parts by weight: 30 parts of Chinese yam, 60 parts of kudzu root, 30 parts of rhizoma polygonati, 60 parts of medlar, 30 parts of epimedium herb, 60 parts of astragalus, 30 parts of raspberry, 60 parts of morinda officinalis, 30 parts of common cnidium fruit, 60 parts of cinnamon, 30 parts of oyster and 60 parts of clove.
The wine prepared by the traditional Chinese medicine composition is prepared by the following steps:
(1) weighing the components in parts by weight, mixing, and mixing according to the weight ratio of 1: 5, adding water into the mixed components in a material-water ratio, decocting for 3 times, each time for 1.0h, combining water decoctions obtained each time, and freeze-drying to obtain Chinese medicinal freeze-dried powder;
(2) inoculating the traditional Chinese medicine freeze-dried powder prepared in the step (1) into a mixed bacterial liquid, wherein the weight ratio of the traditional Chinese medicine freeze-dried powder to the mixed liquid is 1:20, and the mixed bacterial liquid comprises: 2 multiplied by 108cfu/ml of bacillus subtilis, 3 multiplied by 108cfu/ml of lactobacillus casei, 2 multiplied by 108cfu/ml of lactobacillus plantarum, 1 multiplied by 108cfu/ml of bifidobacterium breve and 1 multiplied by 108cfu/ml of microzyme, and carrying out closed fermentation for 30h to prepare a fermentation liquid;
(3) and (2) filtering and filling the fermentation liquor prepared in the step (1) to obtain the wine.
The decoction prepared from the traditional Chinese medicine composition in the embodiment is prepared by the following steps: weighing the components in parts by weight according to the parts by weight, mixing, and mixing according to the weight ratio of 1:15, adding water into the mixed components, decocting for 3 times, each time for 1.0h, and mixing the water decoctions obtained each time to obtain decoction.
Clinical trial
Clinical data: 600 cases of male and female patients with sub-health are provided, the age of the male and female patients is 16-60 years, the male and female patients are randomly divided into six groups, namely a first group, a second group, a third group, a fourth group, a fifth group and a sixth group.
The treatment method comprises the following steps: the first group is drunk by taking the wine prepared in the example 1, the second group is drunk by taking the wine prepared in the example 2, the third group is drunk by taking the wine prepared in the example 3, the fourth group is drunk by taking the decoction prepared in the example 1, the fifth group is drunk by taking the decoction prepared in the example 2, and the sixth group is drunk by taking the decoction prepared in the example 6, wherein the drinking is performed by 50 g every day, and 4 weeks are taken as a treatment course for treating two treatment courses.
The basis of diagnosis is as follows: fatigue, hypodynamia, insomnia, headache, dizziness, poor appetite and other sub-health symptoms.
The evaluation standard of the curative effect is as follows:
and (3) curing: the symptom disappears, and the experiment checks that the symptom is normal;
improvement: the symptoms are obviously improved, and laboratory examination is improved;
the disease is not cured: the primary symptoms are not improved or worsened.
The results of the treatment are shown in Table 1
TABLE 1
Figure 357307DEST_PATH_IMAGE001
As can be seen from the table 1, the invention can improve the sub-health symptoms of fatigue, hypodynamia, insomnia, headache, dizziness, poor appetite and the like, and has obvious curative effect.
Typical cases are:
case 1: in certain plum, male, age 31, the symptoms are marked by easy limb fatigue, hypoqi and hypodynamia; after the medicine is taken, the effect is not achieved, and the wine of the invention is used for treating two courses of treatment, all symptoms are obviously improved.
Case 2: wangzhi, female, age 40, with symptoms of easy sweating, easy dizziness, etc.; after the medicine is taken, the effect is not achieved, and the wine of the invention is used for treating two courses of treatment, all symptoms are obviously improved.
Case 3: zhangzhi, male, age 45, with symptoms such as easy dizziness; after the medicine is taken, the effect is not achieved, and the wine of the invention is used for treating two courses of treatment, all symptoms are obviously improved.

Claims (4)

1. A traditional Chinese medicine composition for conditioning sub-health is characterized by comprising the following components in parts by weight: 30-60 parts of Chinese yam, 30-60 parts of kudzu root, 30-60 parts of rhizoma polygonati, 30-60 parts of medlar, 30-60 parts of epimedium, 30-60 parts of astragalus membranaceus, 30-60 parts of raspberry, 30-60 parts of morinda officinalis, 30-60 parts of fructus cnidii, 30-60 parts of cinnamon, 30-60 parts of oyster and 30-60 parts of clove.
2. The traditional Chinese medicine composition for conditioning sub-health, according to claim 1, is characterized by comprising the following components in parts by weight: 55 parts of Chinese yam, 50 parts of kudzu root, 52 parts of rhizoma polygonati, 45 parts of medlar, 40 parts of epimedium herb, 42 parts of astragalus, 34 parts of raspberry, 38 parts of morinda officinalis, 30 parts of fructus cnidii, 32 parts of cinnamon, 30 parts of oyster and 30 parts of clove.
3. A medicated wine prepared from the Chinese medicinal composition of claim 1 or 2, wherein the medicated wine is prepared by the following steps:
(1) weighing the components in parts by weight, mixing, and mixing according to the weight ratio of 1: adding water into the mixed components in a material-water ratio of 10-15, decocting for 2-3 times, each time for 1-1.5 hours, combining water decoctions obtained each time, and freeze-drying to obtain traditional Chinese medicine freeze-dried powder;
(2) inoculating the traditional Chinese medicine freeze-dried powder prepared in the step (1) into a mixed bacterial liquid, wherein the weight ratio of the traditional Chinese medicine freeze-dried powder to the mixed liquid is 1: 10-20, and the mixed bacterial liquid comprises: 2 multiplied by 108cfu/ml of bacillus subtilis, 3 multiplied by 108cfu/ml of lactobacillus casei, 2 multiplied by 108cfu/ml of lactobacillus plantarum, 1 multiplied by 108cfu/ml of bifidobacterium breve and 1 multiplied by 108cfu/ml of microzyme, and carrying out closed fermentation for 30-50 h to prepare a fermentation liquid;
(3) and (2) filtering and filling the fermentation liquor prepared in the step (1) to obtain the wine.
4. A decoction prepared from the traditional Chinese medicine composition of claim 1 or 2, which is prepared by the following steps: weighing the components in parts by weight, mixing, and mixing according to the weight ratio of 1: adding water into the mixed components in a material-water ratio of 10-15, decocting for 2-3 times, each time for 1-1.5 hours, and combining water decoction obtained each time to obtain decoction.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112006279A (en) * 2020-09-04 2020-12-01 永清县新创科技有限公司 Medicine and food homologous preparation for nourishing bone marrow

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102021106A (en) * 2009-09-18 2011-04-20 劲牌有限公司 Traditional Chinese medicine health wine and production technology thereof
CN106883972A (en) * 2017-03-14 2017-06-23 贵州省仁怀市茅台镇金刚酒业有限公司 A kind of herbaceous plant wine with tonifying kidney and strengthening yang effect
CN108410669A (en) * 2018-05-17 2018-08-17 广州景福精准健康科技有限公司 A kind of health preserving wine and preparation method thereof improving inferior health Qi deficiency physique
CN108567856A (en) * 2018-07-19 2018-09-25 河南迪国科技发展有限公司 A kind of composition and preparation method thereof with benefiting qi and nourishing blood and moistening face
CN110301636A (en) * 2018-11-05 2019-10-08 解中胜 Dual-purpose of drug and food powder with health care function, preparation method and applications

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102021106A (en) * 2009-09-18 2011-04-20 劲牌有限公司 Traditional Chinese medicine health wine and production technology thereof
CN106883972A (en) * 2017-03-14 2017-06-23 贵州省仁怀市茅台镇金刚酒业有限公司 A kind of herbaceous plant wine with tonifying kidney and strengthening yang effect
CN108410669A (en) * 2018-05-17 2018-08-17 广州景福精准健康科技有限公司 A kind of health preserving wine and preparation method thereof improving inferior health Qi deficiency physique
CN108567856A (en) * 2018-07-19 2018-09-25 河南迪国科技发展有限公司 A kind of composition and preparation method thereof with benefiting qi and nourishing blood and moistening face
CN110301636A (en) * 2018-11-05 2019-10-08 解中胜 Dual-purpose of drug and food powder with health care function, preparation method and applications

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112006279A (en) * 2020-09-04 2020-12-01 永清县新创科技有限公司 Medicine and food homologous preparation for nourishing bone marrow

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