CN110711215A - A Chinese medicinal plaster for treating fracture, and its preparation method - Google Patents
A Chinese medicinal plaster for treating fracture, and its preparation method Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/254—Acanthopanax or Eleutherococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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Abstract
The invention discloses a traditional Chinese medicine plaster for treating fracture and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. The traditional Chinese medicine plaster for treating fracture is prepared from the following raw materials in parts by weight: 4-6g of rhizoma coptidis, 4-6g of cortex acanthopanacis, 2-4g of raw rhubarb, 0.5-1.5g of eucommia ulmoides and 40-45g of yellow wine. The invention also discloses a preparation method of the traditional Chinese medicine plaster for treating fracture. The traditional Chinese medicine plaster for treating the fracture is prepared from a plurality of traditional Chinese medicines, has reasonable composition and proper compatibility, fully releases the active ingredients of each component, has the effects of relaxing tendons and activating collaterals, promoting qi and blood circulation, improving blood circulation and promoting fracture healing, and can effectively treat diseases such as fracture, traumatic injury and the like.
Description
Technical Field
The invention relates to a traditional Chinese medicine plaster for treating fracture and a preparation method thereof, belonging to the technical field of traditional Chinese medicines.
Background
Fracture refers to a disease of partial or complete fracture of bone due to trauma or pathology, and the main clinical symptoms are: local pain and tenderness of fracture, local swelling and ecchymosis, complete loss of functional parts of limbs, and deformity and abnormal movement of limbs due to complete bone.
At present, fracture is mainly treated by operation, but soft tissues can be injured again no matter the fracture is cut in the operation or is reset and fixed by the operation, and the risk of complications such as skin infection necrosis, fracture nonunion, joint dysfunction and the like exists.
The Chinese medicine plaster is one of five kinds of Chinese medicine preparation, including bolus, powder, ointment, pellet and decoction, and has unique curative effect on diseases and centralized treatment of affected part. However, the prior art plaster has the defect of insignificant curative effect. In view of the above, there is an urgent need for a Chinese medicinal plaster for treating bone fracture and a preparation method thereof, so as to solve the defects of the prior art.
Disclosure of Invention
The invention aims at providing a Chinese medicinal plaster for treating fracture. The traditional Chinese medicine plaster for treating the fracture is prepared from a plurality of traditional Chinese medicines, has reasonable composition and proper compatibility, fully releases the active ingredients of each component, has the effects of relaxing tendons and activating collaterals, promoting qi and blood circulation, improving blood circulation and promoting fracture healing, and can effectively treat diseases such as fracture, traumatic injury and the like.
The technical scheme for solving the technical problems is as follows: a traditional Chinese medicine plaster for treating fracture is prepared from the following raw materials by weight: 4-6g of rhizoma coptidis, 4-6g of cortex acanthopanacis, 2-4g of raw rhubarb, 0.5-1.5g of eucommia ulmoides and 40-45g of yellow wine.
The rhizoma Ardisiae Gigantifoliae selected by the invention is pungent in taste and warm in nature, enters liver and spleen channels, and has the effects of dispelling wind-damp, strengthening bones and muscles, promoting blood circulation and removing blood stasis; cortex Acanthopanacis, pungent and bitter in flavor and warm in nature, enters liver and kidney meridians, and has effects of dispelling pathogenic wind and dampness, nourishing liver and kidney, strengthening tendons and bones, and inducing diuresis; raw rhubarb, bitter in taste and cold in nature, enters stomach, large intestine, liver and spleen channels, and has the effects of removing food retention, clearing damp-heat, purging fire, cooling blood, removing blood stasis and detoxifying; the eucommia bark vine is bitter in taste, slightly pungent and slightly warm in nature, enters liver and kidney channels, and has the effects of expelling wind-damp and strengthening muscles and bones; yellow wine, Bencao class wood, says that "all kinds of wine are different in alcohol, only rice wine is used as medicine", and rice wine, namely yellow wine, has the efficacies of dredging channels, nourishing intestines and stomach, moistening skin, dissipating moisture, strengthening liver, and dispelling wind and descending qi. The raw materials play a single role, simultaneously play the effects of relaxing tendons and activating collaterals, promoting qi and blood circulation, improving blood circulation and promoting fracture healing, and can effectively treat diseases such as fracture, traumatic injury and the like.
The invention has the beneficial effects that:
(1) the traditional Chinese medicine plaster for treating the fracture is prepared from a plurality of traditional Chinese medicines, has reasonable composition and proper compatibility, fully releases the active ingredients of each component, has the effects of relaxing tendons and activating collaterals, promoting qi and blood circulation, improving blood circulation and promoting fracture healing, and can effectively treat diseases such as fracture, traumatic injury and the like.
(2) The traditional Chinese medicine plaster for treating fracture has the advantages of no toxicity, no side effect, quick and lasting effect and safe and reliable use.
On the basis of the technical scheme, the invention can be further improved as follows.
Further, the feed is prepared from the following raw materials in parts by weight: 4g of rhizoma Ardisiae Gigantifoliae, 6g of cortex Acanthopanacis, 2g of raw rhubarb, 1.5g of eucommia bark vine and 40g of yellow wine.
The adoption of the further beneficial effects is as follows: the traditional Chinese medicine plaster for treating fracture has more obvious drug effect by adopting the mixture ratio of the raw materials.
Further, the feed is prepared from the following raw materials in parts by weight: 5g of rhizoma Ardisiae Gigantifoliae, 5g of cortex Acanthopanacis, 3g of raw rhubarb, 1g of eucommia bark vine and 42g of yellow wine.
The adoption of the further beneficial effects is as follows: the traditional Chinese medicine plaster for treating fracture has more obvious drug effect by adopting the mixture ratio of the raw materials.
Further, the feed is prepared from the following raw materials in parts by weight: 6g of rhizoma Ardisiae Gigantifoliae, 4g of cortex Acanthopanacis, 4g of radix et rhizoma Rhei, 0.5g of caulis Eucommiae and 45g of yellow wine.
The adoption of the further beneficial effects is as follows: the traditional Chinese medicine plaster for treating fracture has more obvious drug effect by adopting the mixture ratio of the raw materials.
The second purpose of the invention is to provide a preparation method of a Chinese medicinal plaster for treating fracture. The preparation method of the traditional Chinese medicine plaster for treating fracture is simple, easy to operate, wide in medicine source, low in cost, wide in market prospect and suitable for popularization and application.
The technical scheme for solving the technical problems is as follows: a preparation method of a Chinese medicinal plaster for treating fracture comprises the following steps: taking 4-6g of rhizoma Ardisiae Gigantifoliae, 4-6g of cortex Acanthopanacis, 2-4g of radix et rhizoma Rhei, and 0.5-1.5g of Eucommiae cortex vine, pulverizing respectively, sieving, adding 40-45g of yellow wine, and concocting into paste to obtain the Chinese medicinal plaster for treating fracture.
The invention has the beneficial effects that:
the preparation method of the traditional Chinese medicine plaster for treating fracture is simple, easy to operate, wide in medicine source, low in cost, wide in market prospect and suitable for popularization and application.
The application method of the traditional Chinese medicine plaster for treating fracture comprises the following steps:
the Chinese medicinal plaster for treating fracture is 2-3g in dosage per plaster. The Chinese medicinal plaster for treating the fracture is applied to the fracture part one time, twice a day, 1 treatment course for 7 days and 1-5 treatment courses.
On the basis of the technical scheme, the invention can be further improved as follows.
Further, the aperture of the sieve is 120 meshes.
The adoption of the further beneficial effects is as follows: the screened aperture is 120 meshes, so that the beneficial components of the raw materials in the traditional Chinese medicine plaster for treating fracture are easier to dissolve out, and the medicine effect is better.
Detailed Description
The principles and features of this invention are described below in conjunction with specific embodiments, which are set forth merely to illustrate the invention and are not intended to limit the scope of the invention.
Example 1:
the traditional Chinese medicine plaster for treating fracture is prepared from the following raw materials in parts by weight: 4g of rhizoma Ardisiae Gigantifoliae, 6g of cortex Acanthopanacis, 2g of raw rhubarb, 1.5g of eucommia bark vine and 40g of yellow wine.
The preparation method of the traditional Chinese medicine plaster for treating fracture comprises the following steps: taking 4g of rhizoma Ardisiae Gigantifoliae, 6g of cortex Acanthopanacis, 2g of raw rhubarb and 1.5g of eucommia bark vine, respectively crushing, sieving with a 120-mesh sieve, adding 40g of yellow wine, and blending into paste to obtain the traditional Chinese medicine plaster for treating fracture.
Example 2:
the traditional Chinese medicine plaster for treating fracture is prepared from the following raw materials in parts by weight: 5g of rhizoma Ardisiae Gigantifoliae, 5g of cortex Acanthopanacis, 3g of raw rhubarb, 1g of eucommia bark vine and 42g of yellow wine.
The preparation method of the traditional Chinese medicine plaster for treating fracture comprises the following steps: respectively pulverizing rhizoma Ardisiae Gigantifoliae 5g, cortex Acanthopanacis 5g, radix et rhizoma Rhei 3g, and Eucommiae cortex vine 1g, sieving with 120 mesh sieve, adding yellow wine 42g, and concocting into paste to obtain the Chinese medicinal plaster for treating fracture.
Example 3:
the traditional Chinese medicine plaster for treating fracture is prepared from the following raw materials in parts by weight: 6g of rhizoma Ardisiae Gigantifoliae, 4g of cortex Acanthopanacis, 4g of radix et rhizoma Rhei, 0.5g of caulis Eucommiae and 45g of yellow wine.
The preparation method of the traditional Chinese medicine plaster for treating fracture comprises the following steps: respectively pulverizing herba Ainsliaeae Rubrinervis 6g, cortex Acanthopanacis Radicis 4g, radix et rhizoma Rhei 4g, and Eucommiae cortex vine 0.5g, sieving with 120 mesh sieve, adding yellow wine 45g, and concocting into paste to obtain the Chinese medicinal plaster for treating fracture.
And (3) clinical observation:
the inventor carries out clinical observation treatment on 28 patients with fracture in 2015 to date, wherein the age is 16-58 years.
1. Method of treatment
The Chinese medicinal plaster for treating the fracture prepared in the embodiment 1, the embodiment 2 or the embodiment 3 is applied to the fracture part once, twice a day, 1 treatment course for 7 days and 1-5 treatment courses. The treatment time is calculated according to the severity of the illness state of the patient, the patient with mild disease takes 1 course of treatment, and the patient with severe disease can be cured after taking 5 courses of treatment.
2. Standard of care
(1) And (3) healing: based on the X-ray image, the fracture line is fuzzy, continuous callus passes through the fracture line, the swelling and pain are eliminated, and the patient can move freely;
(2) the method has the following advantages: the callus is obviously formed, the callus surrounds the fracture broken end, the swelling and pain are eliminated, and the patient can move locally;
(3) and (4) invalidation: no callus or little callus, and obvious swelling and pain.
3. Clinical results
22 cases (78.57%) are cured clinically, 4 cases (14.29%) are effective, 2 cases (7.14%) are ineffective, and the total effective rate is 92.86%.
4. Typical cases
Case 1: some in the land, male, 65 years old, falls down on a rainy road, falls down to injure the left wrist, is painful to press, and has limited activity. The traditional Chinese medicine plaster for treating fracture prepared in the embodiment 1 of the invention is pasted on the left wrist once, twice a day and 7 days for 1 treatment course. After 1 treatment course, the local swelling is obviously relieved, and the pain is obviously relieved. After continuously using for 2 courses of treatment, the fracture is completely healed and the disease is cured through the reexamination of X-ray films.
No recurrence occurred in 6 months of follow-up.
Case 2: if a woman is in 19 years old, the wrong stairs are inadvertently stepped on when the woman goes downstairs, which causes fracture of the right foot and intolerable pain. The traditional Chinese medicine plaster for treating fracture prepared in the embodiment 2 of the invention is pasted on the ankle of the right foot one time, twice a day and 7 days for 1 treatment course. After 1 treatment course, the pain is obviously relieved. The disease is cured after continuously using for 2 courses of treatment. No recurrence occurred in 6 months of follow-up.
Case 3: guo in some women, 18 years old, suffered from bleeding and pain in the left lower limb accompanied by swelling of the left thigh after falling from stairs, and limited mobility. The left femoral shaft fracture is confirmed by X-ray examination. After reduction and fixation by a manipulation, the Chinese medicinal plaster for treating fracture prepared in the embodiment 3 of the invention is stuck to the femoral shaft on the left side, one plaster is applied once, twice a day, and 7 days are 1 course of treatment. After 1 course of treatment, the symptoms are relieved, and the disease is cured after continuously using for 4 courses of treatment. No recurrence occurred in 6 months of follow-up.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (6)
1. A traditional Chinese medicine plaster for treating fracture is characterized by being prepared from the following raw materials in parts by weight: 4-6g of rhizoma coptidis, 4-6g of cortex acanthopanacis, 2-4g of raw rhubarb, 0.5-1.5g of eucommia ulmoides and 40-45g of yellow wine.
2. The Chinese medicinal plaster for treating bone fracture according to claim 1, which is prepared from the following raw materials by weight: 4g of rhizoma Ardisiae Gigantifoliae, 6g of cortex Acanthopanacis, 2g of raw rhubarb, 1.5g of eucommia bark vine and 40g of yellow wine.
3. The Chinese medicinal plaster for treating bone fracture according to claim 1, which is prepared from the following raw materials by weight: 5g of rhizoma Ardisiae Gigantifoliae, 5g of cortex Acanthopanacis, 3g of raw rhubarb, 1g of eucommia bark vine and 42g of yellow wine.
4. The Chinese medicinal plaster for treating bone fracture according to claim 1, which is prepared from the following raw materials by weight: 6g of rhizoma Ardisiae Gigantifoliae, 4g of cortex Acanthopanacis, 4g of radix et rhizoma Rhei, 0.5g of caulis Eucommiae and 45g of yellow wine.
5. A preparation method of a traditional Chinese medicine plaster for treating fracture is characterized by comprising the following steps: taking 4-6g of rhizoma Ardisiae Gigantifoliae, 4-6g of cortex Acanthopanacis, 2-4g of radix et rhizoma Rhei, and 0.5-1.5g of Eucommiae cortex vine, pulverizing respectively, sieving, adding 40-45g of yellow wine, and concocting into paste to obtain the Chinese medicinal plaster for treating fracture.
6. The method for preparing a Chinese medicinal patch for treating bone fracture as claimed in claim 5, wherein the mesh size of the screen is 120 meshes.
Priority Applications (1)
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CN201911065705.0A CN110711215A (en) | 2019-11-04 | 2019-11-04 | A Chinese medicinal plaster for treating fracture, and its preparation method |
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CN201911065705.0A CN110711215A (en) | 2019-11-04 | 2019-11-04 | A Chinese medicinal plaster for treating fracture, and its preparation method |
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CN201911065705.0A Withdrawn CN110711215A (en) | 2019-11-04 | 2019-11-04 | A Chinese medicinal plaster for treating fracture, and its preparation method |
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Application publication date: 20200121 |