CN110709704B - 利用心肌肌钙蛋白i辅助诊断和评估人类受试者的轻度创伤性脑损伤的方法 - Google Patents

利用心肌肌钙蛋白i辅助诊断和评估人类受试者的轻度创伤性脑损伤的方法 Download PDF

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CN110709704B
CN110709704B CN201880036645.7A CN201880036645A CN110709704B CN 110709704 B CN110709704 B CN 110709704B CN 201880036645 A CN201880036645 A CN 201880036645A CN 110709704 B CN110709704 B CN 110709704B
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head injury
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CN110709704A (zh
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B·麦奎斯顿
F·科利
A·贝希里
J·马力诺
S·德特维勒
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    • A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064—Evaluating the brain
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    • G—PHYSICS
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • G01N2800/00—Detection or diagnosis of diseases
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    • G01N2800/00—Detection or diagnosis of diseases
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    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
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    • G01—MEASURING; TESTING
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere

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CN201880036645.7A 2017-05-30 2018-05-30 利用心肌肌钙蛋白i辅助诊断和评估人类受试者的轻度创伤性脑损伤的方法 Active CN110709704B (zh)

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Application Number Priority Date Filing Date Title
US201762512710P 2017-05-30 2017-05-30
US201762512688P 2017-05-30 2017-05-30
US62/512,710 2017-05-30
US62/512,688 2017-05-30
US201762528214P 2017-07-03 2017-07-03
US62/528,214 2017-07-03
PCT/US2018/035232 WO2018222784A1 (en) 2017-05-30 2018-05-30 Methods for aiding in diagnosing and evaluating a mild traumatic brain injury in a human subject using cardiac troponin i

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CN110709704A CN110709704A (zh) 2020-01-17
CN110709704B true CN110709704B (zh) 2024-06-21

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CN201880036454.0A Active CN110720041B (zh) 2017-05-30 2018-05-30 用心肌肌钙蛋白i和早期生物标记物帮助诊断和评价人受试者中轻度创伤性脑损伤的方法

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EP (2) EP3631467A1 (enExample)
JP (2) JP7269183B2 (enExample)
CN (2) CN110709704B (enExample)
AU (2) AU2018275236B2 (enExample)
BR (2) BR112019025313A2 (enExample)
WO (2) WO2018222783A1 (enExample)

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