CN1106856C - Hepatosis treating medicine and its preparation - Google Patents
Hepatosis treating medicine and its preparation Download PDFInfo
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- CN1106856C CN1106856C CN98120453A CN98120453A CN1106856C CN 1106856 C CN1106856 C CN 1106856C CN 98120453 A CN98120453 A CN 98120453A CN 98120453 A CN98120453 A CN 98120453A CN 1106856 C CN1106856 C CN 1106856C
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Abstract
The present invention discloses a new medicine for treating liver diseases, which is mainly used for treating hepatitis B, hepatocirrhosis, etc. The medicine is prepared from notoginseng, leech, chicken's gizzard membrane, red sage root, raw white peony, corydalis tuber, oldenlandia diffusa and herba abri cantoniensisis as raw materials according to certain proportions. Various preparations, such as watered pills, etc., can be prepared after the medicines are respectively processed according to the different characteristics of the medicines. The present invention has the advantage of unique formula and preparation method, and the new medicine can treat both the manifestation and the root cause of a disease with obvious curative effects.
Description
The present invention relates to a kind of medicine for the treatment of hepatopathy, specifically a kind of is the Chinese patent medicine of the treatment hepatopathy made of raw material with the Chinese herbal medicine, the invention still further relates to the preparation method of this medicine.
Hepatopathy is that a kind of sickness rate is high, the common disease of serious harm human health.Wherein hepatitis generally is that infection owing to hepatitis virus causes.Have now found that 7 types hepatitis virus, and wherein especially the sickness rate with hepatitis B is the highest.Hepatitis B virus is a kind of spheroidal crystal granule, shell is surface antigen (HBSAg), include e antigen (HBeAg) and cAg (HBCAg), surface antigen (HBSAg), e antigen (HBeAg) and the equal positive person of core antibody (HBCAg) are great three positive, duplicate with infection ability strong.Surface antigen (HBSAg), core antibody (anti--HBC) positive person be a small three positive, be in a little less than the infection convalescent period infectiousness, but carry easy development hepatocarcinoma for a long time.At present the acute hepatitis b patient is not still had ideal Therapeutic Method, generally adopt the method treatment of the liver protecting and ALT lowering.More do not have effective measures for the chronic viral hepatitis B patient, generally adopt antiviral therapy, but the negative conversion rate difference is big, also easily recurrence.
Liver cirrhosis also is a kind of common chronic progressive external hepatopathy in addition, and is very harmful to human body, and at present for the treatment of liver cirrhosis for just eliminating its symptom, as the abdominal distention digestant, edema, ascites is then with diuretic or benefit albumen medicine, all takes stopgap measures and do not effect a permanent cure.
The object of the present invention is to provide a kind of medicine for the treatment of hepatopathys such as hepatitis B and liver cirrhosis, have heat-clearing and toxic substances removing, activating blood circulation to dissipate blood stasis, dampness removing and moisturize digestant function, have the anti-liver injury effect, strengthen liver metabolism, promote liver function recovery, can prevent that the hepatocyte fibrosis from taking place.When taking stopgap measures, can effect a permanent cure.
Another object of the present invention provides the preparation method of this remedies for liver diseases.
Solution of the present invention is based on the understanding of motherland's medical science to the mechanism of hepatopathy, the i.e. theory of " 4 o'clock one, six gas one, all things on earth one, day human rights should ", adopted the theory " four guiding principle eight therapeutic methods " of the Chinese traditional treatment hepatopathy of taking the course of its own, four guiding principles are promptly dredged stomach, tonifying the spleen, the kidney invigorating, are invigorated blood circulation, and eight therapeutic methods refer to distinguish deficiency and excess, cold, heat, bright specimen, negative and positive.From motherland medicine treasure-house, filter out heat-clearing and toxic substances removing, soothing liver-QI silt, kidney and spleen invigorating, dampness removing and moisturize that digestant natural drug prescription forms.
Medicine of the present invention is owing to following component is made: (consumption is a weight portion)
Radix Ginseng Rubra 50-60 Radix Notoginseng 20-30 Radix Paeoniae Alba 50-60
Hirudo 20-30 Endothelium Corneum Gigeriae Galli 20-30 Rhizoma Corydalis 20-30
Herba Hedyotidis Diffusae 50-60 Herba Chrysopogonis Aciculati 50-60
Formula optimization weight (part) ratio range of preparation medicine of the present invention is:
Radix Ginseng Rubra 50 Radix Notoginseng 20 Radix Paeoniae Alba 50
Hirudo 20 Endothelium Corneum Gigeriae Galli 20 Rhizoma Corydalis 20
Herba Hedyotidis Diffusae 50 Herba Chrysopogonis Aciculatis 50
Herba Hedyotidis Diffusae in the medicine of the present invention, Herba Chrysopogonis Aciculati heat-clearing and toxic substances removing, the strong spleen of soothing liver-QI is a monarch drug; Radix Ginseng Rubra, Radix Paeoniae Alba kidney and spleen invigorating, blood-supplementing blood-nourishing are ministerial drug; Radix Notoginseng, Hirudo blood circulation promoting and blood stasis dispelling are adjuvant drug; Endothelium Corneum Gigeriae Galli, the Rhizoma Corydalis soothing liver-QI is pleasant is messenger drug.All medicine synergism and reach kidney and spleen invigorating, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, the effectiveness of liver-smoothing, qi-regulating.
Medicine of the present invention can be made various dosage forms according to a conventional method.Preferred water pill-type wherein.
Watered pill preparation method:
1. Radix Notoginseng, Hirudo, Endothelium Corneum Gigeriae Galli are ground into fine powder;
2. Radix Ginseng Rubra, Radix Paeoniae Alba, Rhizoma Corydalis, Herba Hedyotidis Diffusae, Herba Chrysopogonis Aciculati are decocted with water three times, be condensed into thick paste after three decocting liquids are merged;
3. above-mentioned fine powder is added mixing in the thick paste, oven dry is pulverized, and sterilization adds an amount of Cera Flava and water, makes the watered pill, packing.
For showing the therapeutic effect of medicine of the present invention to hepatopathy, the hepatopathy case that reaches all ages and classes, sex of types such as hepatitis B, liver cirrhosis has been selected by system, uses medicine of the present invention to treat, and be 20 days a course of treatment.
Instructions of taking: every day secondary, each 6 the gram.Its therapeutic effect can be added up referring to table 1 clinical data.Treatment cycle is 4-5 the course of treatment.
Produce effects: transference cure, great three positive, small three positive are turned out cloudy, and albumen is normal;
Effectively: symptom is most of to disappear, and great three positive, small three positive are partly turned out cloudy;
Invalid: symptom does not have significant change, great three positive, small three positive no change.
Table 1 clinical data statistics
| The course of disease | Age group (year) | Produce effects | Effectively | Invalid |
| Below 3 months | 110 | 150 | 0 | |
| In 20 years | 20-30 30-40 40-50 | 50 35 20 | 60 25 10 | 0 0 40 |
| Effective percentage 46% 53% 8% | ||||
By above-mentioned clinical data as seen, medicine treating both the principal and secondary aspects of a disease of the present invention not only can be eliminated the symptom of hepatopathys such as hepatitis B and liver cirrhosis quickly, and can make leading indicator such as great three positive, small three positive, albumen etc. that tangible improvement is arranged.Taking convenience, patient easily accepts, and side effect is little, and expense is low, instant effect, most of being difficult for recurs.
Embodiment takes by weighing raw material (kilogram) by following proportioning: Radix Ginseng Rubra 50 Radix Notoginseng 20 Radix Paeoniae Alba 50 Hirudos 20 Endothelium Corneum Gigeriae Galli 20 Rhizoma Corydalis 20 Herba Hedyotidis Diffusaes 50 Herba Chrysopogonis Aciculatis 50 watered pill preparation methoies:
1. Radix Notoginseng, Hirudo, Endothelium Corneum Gigeriae Galli are ground into fine powder and cross 1000 mesh sieves;
2. Radix Ginseng Rubra, Radix Paeoniae Alba, Rhizoma Corydalis, Herba Hedyotidis Diffusae, Herba Chrysopogonis Aciculati are decocted with water three times, each water open the back decoct 40 minutes (first takes 150 liters of decocting liquids, second fry in shallow oil and the 3rd fry in shallow oil all get 100 liters of decocting liquids), be condensed into thick paste after will three decocting liquids merging;
3. above-mentioned fine powder is added mixing in the thick paste, oven dry, pulverized 1000 mesh sieves after, sterilization adds an amount of Cera Flava and water, makes the watered pill, every ball weighs 0.03 gram, packing.Model case:
1. Man Yuhua, the woman, 68 years old, Zhengzhou rail man family members, suffering from liver cirrhosis ascites lived for several times that hospital has all only alleviated partial symptoms, and expense is high not to reach a cure yet.Bad, the weak dizziness of appetite, abdominal distention during prescription on individual diagnosis, B ultrasonic prompting cirrhotic ascites, 68 millimeters of splenomegalies, 90 millimeters of ascites, 15 millimeters of portal veins, liver dwindles.Take medicine of the present invention after five courses of treatment, chemical examination albumen is normal, 40 millimeters of spleens, and 13 millimeters of portal veins, transference cure now can cook one's own food.
2. Li Zhi is big, the man, and 12 years old, people from Minquan County suffered from hepatitis B.Take three courses of treatment of medicine of the present invention, great three positive is turned out cloudy and is produced antibody.
3. Yan is full adopted, the man, and 18 years old, people from Wen County suffered from hepatitis B.Take medicine of the present invention after two courses of treatment, small three positive is turned out cloudy.
Claims (6)
1. medicine for the treatment of hepatopathy is characterized in that it is the medicament of being made by the following weight proportion raw material:
Radix Ginseng Rubra 50-60 Radix Notoginseng 20-30 Radix Paeoniae Alba 50-60
Hirudo 20-30 Endothelium Corneum Gigeriae Galli 20-30 Rhizoma Corydalis 20-30
Herba Hedyotidis Diffusae 50-60 Herba Chrysopogonis Aciculati 50-60.
2. the medicine of treatment pneumonopathy according to claim 1, wherein the weight proportion of each raw material is:
Radix Ginseng Rubra 50 Radix Notoginseng 20 Radix Paeoniae Alba 50
Hirudo 20 Endothelium Corneum Gigeriae Galli 20 Rhizoma Corydalis 20
Herba Hedyotidis Diffusae 50 Herba Chrysopogonis Aciculatis 50.
3. the medicine of treatment hepatopathy according to claim 1 and 2 is characterized in that said medicament is a said dosage form on any pharmaceutics.
4. the medicine of treatment hepatopathy according to claim 3 is characterized in that said medicament is a watered pill.
5. according to the preparation method of the said treatment liver disease drug of claim 4, it is characterized in that: Radix Notoginseng, Hirudo, Endothelium Corneum Gigeriae Galli are ground into fine powder; In addition Radix Ginseng Rubra, Radix Paeoniae Alba, Rhizoma Corydalis, Herba Hedyotidis Diffusae, Herba Chrysopogonis Aciculati are decocted with water three times, be condensed into thick paste after three decocting liquids are merged; Again above-mentioned fine powder is added mixing in the thick paste, oven dry is pulverized, and sterilization adds an amount of Cera Flava and water, makes the watered pill, packing.
6. the preparation method of the medicine of treatment hepatopathy according to claim 5, the weight that it is characterized in that the said watered pill are 0.03 gram.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98120453A CN1106856C (en) | 1998-10-22 | 1998-10-22 | Hepatosis treating medicine and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98120453A CN1106856C (en) | 1998-10-22 | 1998-10-22 | Hepatosis treating medicine and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1252287A CN1252287A (en) | 2000-05-10 |
| CN1106856C true CN1106856C (en) | 2003-04-30 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98120453A Expired - Fee Related CN1106856C (en) | 1998-10-22 | 1998-10-22 | Hepatosis treating medicine and its preparation |
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| Country | Link |
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| CN (1) | CN1106856C (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103520560B (en) * | 2013-10-31 | 2015-01-07 | 李凯 | Traditional Chinese medicine for treating obesity |
| CN105213975A (en) * | 2015-10-19 | 2016-01-06 | 青岛市中心医院 | A kind of pharmaceutical composition and application thereof for the treatment of liver cirrhosis |
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1998
- 1998-10-22 CN CN98120453A patent/CN1106856C/en not_active Expired - Fee Related
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| Publication number | Publication date |
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| CN1252287A (en) | 2000-05-10 |
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